CN107320527A - A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of mulberry leaf - Google Patents
A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of mulberry leaf Download PDFInfo
- Publication number
- CN107320527A CN107320527A CN201710738952.7A CN201710738952A CN107320527A CN 107320527 A CN107320527 A CN 107320527A CN 201710738952 A CN201710738952 A CN 201710738952A CN 107320527 A CN107320527 A CN 107320527A
- Authority
- CN
- China
- Prior art keywords
- mulberry leaf
- squeezing
- concoction
- fresh
- preparation technology
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of mulberry leaf.The technique is cleaned, eluted, and take advantage of fresh squeezing, leaching concoction after the harvesting of mulberry leaf medicinal material.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is dried in vacuo, and is vacuum-packed after crushing.Mulberry Leaf medicine materical crude slice prepared by this method, remains the polarity and nonpolar active ingredient in medicinal material to greatest extent.Medicine materical crude slice is beneficial to accumulating, convenient to adjust, quality controllable, and curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there is significant social effect and economic benefit.
Description
Technical field
The invention belongs to the processing technology of Chinese medicine manufacture field, more particularly to Chinese medicine mulberry leaf medicine materical crude slice.
Background technology
Chinese medicine mulberry leaf are moraceae plants mulberryMorus alba L. dried leaf.This product has wind and heat dispersing, clears liver and improve vision,
The effects such as removing heat from the lung to relieve cough, it is mainly used in the treatment of the diseases such as anemopyretic cold, cough with lung heat, liver-yang hyperactivity, deficiecny of liver-YIN.
The processing mode of conventional mulberry leaf medicine materical crude slice is：Mulberry leaf are harvested after first frost, impurity is removed, dries, then accumulating of packing.This
Class medicine materical crude slice, bulky, Hygienic Index is poor, easily pollutes and goes mouldy, quality it is difficult to ensure that, be unfavorable for formula adjust and ensure
Its clinical efficacy, in addition to patient bring recessiveness harm.
At present, in the market also has the granule pieces sale that mulberry leaf medicinal material is made after extraction.The preparation of granule pieces
Journey, extracts not only time consumption and energy consumption, and is difficult to be extracted because commonly using substantial amounts of water to do the nonpolar active ingredient in solvent, medicinal material
Out.Further, since the mulberry leaf medicinal material of extraction is also to dry and by storage for a long time, therefore, the loss of active ingredient
It is also very big.In order to ensure the clinic of mulberry leaf medicinal material is effective, steady quality, a kind of new mulberry leaf medicine materical crude slice is urgently developed.
The content of the invention
The invention discloses " a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of mulberry leaf ".This technique can be maximum
Retain the polarity and nonpolar active ingredient in mulberry leaf medicinal material while limit, it is to avoid medicinal material is processed and accumulating in existing medicine materical crude slice
During caused by active ingredient loss and the decline of medical material quanlity, reduce medicinal material by mould etc. pollution, to ensuring mulberry leaf
The steady quality and clinical safety of medicine materical crude slice effectively have great importance.
To achieve these goals, the technical scheme is that：
After mulberry leaf harvesting, clean, be cut into the wide pieces of 1 ~ 2cm, add the water of 0.5 ~ 1 times of amount of medicinal material weight, stir 15 ~ 30 points
Clock, takes advantage of fresh squeezing, collects and just squeezes concoction, and the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice, the remaining dregs of a decoction are again
Add 1 ~ 5 times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 100 ~ 200 mesh screens obtain mulberry leaf
Concoction.Obtained mulberry leaf concoction is concentrated under reduced pressure into the medicinal extract that relative density is 1.05 ~ 1.30 under the conditions of 40 ~ 75 DEG C, and will
It crushed 60 ~ 120 mesh sieves after being dried in vacuo 4 ~ 8 hours in 40 ~ 70 DEG C, was vacuum-packed, and produces fresh squeeze of mulberry leaf and is dried in vacuo powder
Last medicine materical crude slice.
On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, medicine materical crude slice manufacturer, the date of manufacture,
The information such as Contents of Main Components, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.Mulberry leaf are enclosed in bag
Thin layer differentiates collection of illustrative plates and/or efficient liquid phase characteristic spectrum, is used as " identity card " of product.In addition, in the packaging bag of product, print
There is Quick Response Code, former plant photo, medicinal material photo, medicine materical crude slice photo, character and the micro- mirror for obtaining product can be linked by scanning
The information such as other feature.
The present invention is advantageous in that：
The mulberry leaf medicinal material of fresh collection, cleans and is directly squeezed after washing, filter, be concentrated under reduced pressure, being dried in vacuo, resulting powder
Medicine materical crude slice, the active ingredient in medicinal material can be retained to greatest extent.This medicine materical crude slice volume compared to traditional medicine materical crude slice volume greatly
Reduce, vacuum packaging so that prepared slice quality is more stablized, adjusted beneficial to accumulating and clinic, with very significant social effect
And economic implications.
Embodiment
Embodiment 1
By the mulberry leaf medicinal material of fresh collection, clean, be cut into the wide pieces of 1cm, add the water of 0.5 times of amount of medicinal material weight, stir 15 points
Clock, takes advantage of fresh squeezing, collects and just squeezes concoction, and the dregs of a decoction add the water of 5 times of amounts, stir 5min, press extracting juice, and the remaining dregs of a decoction add 5
Times amount water, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 100 mesh screens obtain mulberry leaf concoction.It will obtain
Mulberry leaf concoction be concentrated under reduced pressure, temperature is set as 65 DEG C.When medicinal extract relative density obtained by concentration is 1.15, it is transferred to vacuum and does
In dry case, dried 8 hours in 60 DEG C, 60 mesh sieves are crossed after crushing, pack, adds packed antioxidant and drier, very by 1kg/ bags
Sky encapsulation.
Embodiment 2
By the mulberry leaf medicinal material of fresh collection, clean, be cut into the wide pieces of 2cm, add the water of 1 times of amount of medicinal material weight, stir 30 minutes,
Fresh squeezing is taken advantage of, collects and just squeezes concoction, the dregs of a decoction add the water of 5 times of amounts, stir 10min, press extracting juice, and the remaining dregs of a decoction add 3 times
The water of amount, press extracting juice, merge just squeeze concoction and after squeeze concoction twice, 200 mesh screens obtain mulberry leaf concoction.By what is obtained
Mulberry leaf concoction is concentrated under reduced pressure, and temperature is set as 70 DEG C.When medicinal extract relative density obtained by concentration is 1.10, vacuum drying is transferred to
In case, dried 6 hours in 65 DEG C, 60 mesh sieves are crossed after crushing, pack, adds packed antioxidant and drier, vacuum by 1kg/ bags
Encapsulation.
Above example, only illustrates the technological thought of this invention, it is impossible to whereby limit protection scope of the present invention all
It is any change done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention was protected
Within the scope of.
Claims (2)
1. a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of mulberry leaf, it is characterised in that：After mulberry leaf harvesting, clean, cut
Into the wide pieces of 1 ~ 2cm, the water of 0.5 ~ 1 times of amount of medicinal material weight is added, is stirred 15 ~ 30 minutes, fresh squeezing is taken advantage of, collects and just squeezes concoction,
The dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, press extracting juice, and the remaining dregs of a decoction add the water of 1 ~ 5 times of amount, press extracting juice,
Merge just squeeze concoction and after squeeze concoction twice, 100 ~ 200 mesh screens obtain mulberry leaf concoction.
2. a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of mulberry leaf according to claim 1, it is characterised in that：Will
The mulberry leaf concoction obtained in claim 1 is concentrated under reduced pressure into the medicinal extract that relative density is 1.05 ~ 1.30 under the conditions of 40 ~ 75 DEG C,
And 60 ~ 120 mesh sieves were crushed after it is dried in vacuo 4 ~ 8 hours in 40 ~ 70 DEG C, it is vacuum-packed, produces the fresh vacuum of squeezing of mulberry leaf and do
Dry powder decoction pieces.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710738952.7A CN107320527A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of mulberry leaf |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710738952.7A CN107320527A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of mulberry leaf |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107320527A true CN107320527A (en) | 2017-11-07 |
Family
ID=60224895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710738952.7A Pending CN107320527A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of mulberry leaf |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107320527A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105193920A (en) * | 2015-11-14 | 2015-12-30 | 芜湖天成普阳中药科技有限公司 | Freshly squeezed vacuum drying peppermint powdery decoction pieces and preparation process thereof |
| CN105194009A (en) * | 2015-11-14 | 2015-12-30 | 芜湖天成普阳中药科技有限公司 | Freshly squeezed vacuum drying spreading hedyotis herb powdery decoction pieces and preparation process thereof |
| CN105193894A (en) * | 2015-11-14 | 2015-12-30 | 芜湖天成普阳中药科技有限公司 | Freshly squeezed vacuum drying cholla stem powdery decoction pieces and preparation process thereof |
| CN105213473A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Menthae fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
| CN105213740A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Aloe fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105213551A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Hedyotidis Diffusae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
-
2017
- 2017-08-25 CN CN201710738952.7A patent/CN107320527A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105193920A (en) * | 2015-11-14 | 2015-12-30 | 芜湖天成普阳中药科技有限公司 | Freshly squeezed vacuum drying peppermint powdery decoction pieces and preparation process thereof |
| CN105194009A (en) * | 2015-11-14 | 2015-12-30 | 芜湖天成普阳中药科技有限公司 | Freshly squeezed vacuum drying spreading hedyotis herb powdery decoction pieces and preparation process thereof |
| CN105193894A (en) * | 2015-11-14 | 2015-12-30 | 芜湖天成普阳中药科技有限公司 | Freshly squeezed vacuum drying cholla stem powdery decoction pieces and preparation process thereof |
| CN105213473A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Menthae fresh squeezing spray-dried powders decoction pieces and preparation technology thereof |
| CN105213740A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Aloe fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
| CN105213551A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Hedyotidis Diffusae fresh squeezing spray-dried granules decoction pieces and preparation technology thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20171107 |
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| WD01 | Invention patent application deemed withdrawn after publication |