CN107287239A - 一种用于视网膜色素变性的基因治疗载体及药物 - Google Patents
一种用于视网膜色素变性的基因治疗载体及药物 Download PDFInfo
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- CN107287239A CN107287239A CN201710231239.3A CN201710231239A CN107287239A CN 107287239 A CN107287239 A CN 107287239A CN 201710231239 A CN201710231239 A CN 201710231239A CN 107287239 A CN107287239 A CN 107287239A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/04—Phosphoric diester hydrolases (3.1.4)
- C12Y301/04001—Phosphodiesterase I (3.1.4.1)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Abstract
Description
Claims (15)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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CN201610221259 | 2016-04-11 | ||
CN2016102212598 | 2016-04-11 |
Publications (2)
Publication Number | Publication Date |
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CN107287239A true CN107287239A (zh) | 2017-10-24 |
CN107287239B CN107287239B (zh) | 2020-09-22 |
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Application Number | Title | Priority Date | Filing Date |
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CN201710231239.3A Active CN107287239B (zh) | 2016-04-11 | 2017-04-11 | 一种用于视网膜色素变性的基因治疗载体及药物 |
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CN (1) | CN107287239B (zh) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008065430A2 (en) * | 2006-12-01 | 2008-06-05 | Oxford Biomedica (Uk) Limited | Promoter construct |
WO2008127675A1 (en) * | 2007-04-13 | 2008-10-23 | Tufts University | Compositions and methods for retinal transduction and photoreceptor specific transgene expression |
WO2008137066A1 (en) * | 2007-05-02 | 2008-11-13 | The Board Of Regents Of The University Of Oklahoma | Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases |
WO2015142941A1 (en) * | 2014-03-17 | 2015-09-24 | Avalanche Biotechnologies, Inc. | Compositions and methods for enhanced gene expression in cone cells |
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2017
- 2017-04-11 CN CN201710231239.3A patent/CN107287239B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008065430A2 (en) * | 2006-12-01 | 2008-06-05 | Oxford Biomedica (Uk) Limited | Promoter construct |
WO2008127675A1 (en) * | 2007-04-13 | 2008-10-23 | Tufts University | Compositions and methods for retinal transduction and photoreceptor specific transgene expression |
WO2008137066A1 (en) * | 2007-05-02 | 2008-11-13 | The Board Of Regents Of The University Of Oklahoma | Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases |
WO2015142941A1 (en) * | 2014-03-17 | 2015-09-24 | Avalanche Biotechnologies, Inc. | Compositions and methods for enhanced gene expression in cone cells |
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Publication number | Publication date |
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CN107287239B (zh) | 2020-09-22 |
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Effective date of registration: 20210803 Address after: 110003 1-18-3, No. 18-1, Sanhao Street, Heping District, Shenyang City, Liaoning Province Patentee after: Pang Jijing Address before: 350200 unit 1001, 10th floor, Haicang international logistics building, No. 29, Jiangang Road, Xiamen area, China (Fujian) pilot Free Trade Zone, Xiamen, Fujian d0630 Patentee before: Xiamen Zi Jing Biological Technology Co.,Ltd. |
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Effective date of registration: 20211222 Address after: 110000 Room 101, No. 66-23, Sishui street, Hunnan District, Shenyang City, Liaoning Province Patentee after: Shenyang Weijing Biotechnology Co.,Ltd. Address before: 110003 1-18-3, No. 18-1, Sanhao Street, Heping District, Shenyang City, Liaoning Province Patentee before: Pang Jijing |
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