CN107233446A - A kind of medical chitosan oligosaccharide complexing agent dressing and preparation method thereof - Google Patents
A kind of medical chitosan oligosaccharide complexing agent dressing and preparation method thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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Abstract
The invention discloses a kind of medical chitosan oligosaccharide complexing agent dressing and preparation method thereof.The medical chitosan oligosaccharide complexing agent dressing includes the following substances counted by weight：69 parts of phellodendron extract, 35 parts of Pollen Tyjphae extract, 56 parts of licorice, 68 parts of Realgar extract, 26 parts of mint extract, 35 parts of Radix Gentianae extract, 35 parts of Indigo Naturalis extract, 13 parts of borneol, 35 parts of gypsum, 47 parts of pearl powder, 68 parts of calamine, 58 parts of alumen, 10 15 parts of chitosan.The dressing is gentle, non-stimulated, plays the role of to cervical erosion good, and can detoxify analgesic therapy, myogenic sore, rotten promoting blood circulation of dispelling, and removes necrosis and promote granulation, myogenic is put on flesh.
Description
Technical field
The present invention relates to pharmaceutical technology field, more particularly to a kind of medical chitosan oligosaccharide complexing agent dressing and preparation method thereof.
Background technology
At present, Amino-Cerv field typically uses pill, washing lotion and effervescent tablet, and pill is easy to injure vagina inner membrance
Wall, the acid-base balance that washing lotion easily changes vagina environment causes resistance to decline, and effervescent tablet absorbs and drug effect can not all reach
Satisfied result.
In addition, the medicine for the treatment gynecological disease of vagina has very strong excitant, not gently, do not hinder in vagina
In the case of mouthful, the reproductive organs tissues such as injury vagina are also easy to.
Moreover, the main method in the prior art for cervical erosion is oral drugs and operative treatment, oral medicine
Thing is transported to body everywhere after gastrointestinal absorption through blood circulation, is actually reached the quantity of uterine neck and will be greatly decreased, effect does not show
Write, and be also easy to injure digestive system.
The content of the invention
In order to solve the above technical problems, the present invention provides a kind of gentle, non-stimulated, the doctor of cervical erosion can be quickly repaired
With chitosan oligosaccharide complexing agent dressing.
In order to realize the technique effect of the present invention, employ following technical scheme and be achieved：
A kind of medical chitosan oligosaccharide complexing agent dressing, including the following substances counted by weight：6-9 parts of phellodendron extract,
3-5 parts of Pollen Tyjphae extract, 5-6 parts of licorice, 6-8 parts of Realgar extract, 2-6 parts of mint extract, Radix Gentianae extract
3-5 parts, 3-5 parts of Indigo Naturalis extract, 1-3 parts of borneol, 3-5 parts of gypsum, 4-7 parts of pearl powder, 5-8 parts of alumen of 6-8 parts of calamine,
10-15 parts of chitosan.
The phellodendron extract, Pollen Tyjphae extract, licorice, Realgar extract, mint extract, felwort are extracted
Thing and Indigo Naturalis extract selection supercritical carbon dioxide extracting, are the oxidation in order to effectively prevent heat-sensitive substance and ease
Dissipate, whole compositions of medicinal plant are remain in extract, and higher boiling, low volatility, the material being easily pyrolyzed can be existed
Extracted below its boiling temperature.
As a further improvement, each material of medical chitosan oligosaccharide complexing agent dressing does following proportioning according to parts by weight：
7 parts of phellodendron extract, 4 parts of Pollen Tyjphae extract, 6 parts of licorice, 7 parts of Realgar extract, 4 parts of mint extract, felwort
4 parts of extract, 4 parts of Indigo Naturalis extract, 2 parts of borneol, 4 parts of gypsum, 6 parts of pearl powder, 7 parts of calamine, 6 parts of alumen, chitosan
13 parts.
The borneol, gypsum and pearl powder are powder.
The calamine is that the too quickly cannon system of skilled 9 light-coloured vinegars is formed, and the alumen is that boiling water boiling is formed.
The application in cervical erosion is repaired present invention also offers medical chitosan oligosaccharide complexing agent dressing, medical chitosan oligosaccharide is answered
Mixture dressing is used in vagina；Its application process is：Medical chitosan oligosaccharide complexing agent dressing is directly applied into intravaginal；Its is specific
Application process is：Vagina and uterine neck secretions are first cleaned with 0.1% anti-inflammation liquid, medicaments uniformity is then applied to affected part.
Present invention also offers the preparation method of medical chitosan oligosaccharide complexing agent dressing, the preparation of the dressing is according to following work
Skill step：Phellodendron extract, Pollen Tyjphae extract, licorice, Realgar extract, mint extract, rough gentian are weighed in proportion
Careless extract, Indigo Naturalis extract, borneol, gypsum, pearl powder, calamine, alumen, are placed in 8~12min of stirring in agitator,
Chitosan is added after mixing, 5~10min is again stirring for, bottling is well mixed.
Beneficial effects of the present invention are as follows：
1) medical chitosan oligosaccharide complexing agent dressing of the invention, gently, non-stimulated, is difficult to produce infringement to vagina.
2) complexing agent dressing is sent out using chitosan oligosaccharide of the present invention, can quickly repairs cervical erosion, not only application method is simple,
Damage will not be produced to human body, and using effect is good.
3) medical chitosan oligosaccharide complexing agent dressing of the invention is used, can also detoxify analgesic therapy, myogenic sore, rotten promoting blood circulation of dispelling is gone
Necrotic tissue and promoting muscle growing, myogenic is put on flesh.
Embodiment
Embodiment 1
A kind of medical chitosan oligosaccharide complexing agent dressing, including the following substances counted by weight：6 parts of phellodendron extract, Pu
Yellow 3 parts of extract, 5 parts of licorice, 6 parts of Realgar extract, 2 parts of mint extract, 3 parts of Radix Gentianae extract, indigo naturalis are carried
Take 3 parts of thing, 1 part of borneol, 3 parts of gypsum, 4 parts of pearl powder, 6 parts of calamine, 5 parts of alumen, 10 parts of chitosan.
Said composition preparation method is：
First, phellodendron extract, Pollen Tyjphae extract, licorice, Realgar extract, mint extract, felwort carry
Take thing, Indigo Naturalis extract by supercritical carbon dioxide extracting, carried out close under room temperature (35-40 DEG C) and CO2 gas blankets
Extract, effectively prevent the oxidation and loss of heat-sensitive substance, whole compositions of medicinal plant are remain in extract, and
And higher boiling, low volatility, the material being easily pyrolyzed can be extracted below its boiling temperature, meanwhile, CO2 is a kind of not live
Bold and vigorous gas, extraction process does not chemically react, and belongs to non-flammable gases, tasteless, odorless, nontoxic, therefore security is good；When
Right CO2 is cheap, and purity is high, easily obtains, and recycles in process of production, so as to reduce cost.Phellodendron extract,
Pollen Tyjphae extract, licorice, Realgar extract, mint extract, Radix Gentianae extract, Indigo Naturalis extract are purchased by outside
Buy gained.
Secondly：Calamine is that the too quickly cannon system of skilled 9 light-coloured vinegars is formed, and calamine is fired on vigorous fire, works as stove
Sweet stone, which is put into after reddening in light-coloured vinegar, to carry out invading bubble filtering, then takes out to be fired again and invades bubble again, processes and filter by nine times
So that the purity of calamine reaches maximum, then again pure calamine break into it is powdered.
Again：Alumen is that boiling water boiling is formed, and is that alumen is put into boiling water to carry out hotting plate 30~40min, takes out cooling
Alumen is broken into afterwards powdered.
Finally：In a nitrogen environment, by various composition in composition, (such as various composition is extracted for golden cypress in the present embodiment
Thing, Pollen Tyjphae extract, licorice, Realgar extract, mint extract, Radix Gentianae extract, Indigo Naturalis extract, borneol,
Gypsum, pearl powder, calamine alumen, chitosan) measure as required well mixed, is fitted into and is provided with the bottle of conduit, use
Nitrogen, it is to avoid the oxygen in air enters in medical chitosan oligosaccharide complexing agent dressing.
Said composition application process is：Medical chitosan oligosaccharide complexing agent dressing is directly sent using the bottle provided with pipe guide
Enter intravaginal, conduit is connected with the top of bottle, the bottle is in antimicrobial protection box.Specially：
The first step, vagina and uterine neck secretions are first cleaned with 0.1% anti-inflammation liquid, and (substantially, dense sexual secretion is more for inflammation
Person can take the circumstances into consideration to be wiped with sterilized cotton ball to wash).
Second step, opens antimicrobial protection box, takes out bottle.
3rd step, opens conduit, adjustment angle, and bottle is inverted.Vagina is inserted for ease of conduit, bottle must fall
Put and use.
4th step, shake well makes various materials be sufficiently mixed uniformly.
5th step, inserts the catheter into intravaginal, can select suitable position according to environment.
6th step, gently presses pressure valve, and dressing in bottle is discharged, and consumption is defined by feeling full of vaginal canal.
By the complexing agent dressing of embodiment 1 be used for 100 with cervical erosion subjects (cervical erosion be divided into I degree-compared with
Gently；II degree-heavier；III degree-serious).
After complexing agent dressing of the present invention three days：For pudendal pruritus caused by cervical erosion unbearably, leucorrhea increasing, evil
The symptom such as dew is not net, peculiar smell, the soreness of waist stomachache, uterus are touched a tender spot, with obvious inhibitory action, 80% with cervical erosion by
Examination person part is improved.
After complexing agent dressing of the present invention seven days：80% subject with cervical erosion starts to scab.
After complexing agent dressing of the present invention 15 days：80% subject with cervical erosion is initially located in growth shape
State.
After complexing agent dressing of the present invention 30 days：98% subject with I degree of cervical erosion repairs degree and is averaged
Level before illness is reached, 90% subject with II degree of cervical erosion repairs degree and averagely reaches more than 75%, and 90% suffers from
The subject of III degree of cervical erosion repairs degree and averagely reaches more than 60%.
After complexing agent dressing of the present invention 45 days：98% subject with I degree of cervical erosion is also complete
The level before illness is reached, and the immunologic function of vagina is improved, and 80% subject with II degree of cervical erosion repaiies
Multiple degree averagely reaches level before illness.
After complexing agent dressing of the present invention 60 days：98% subject with I degree of II degree of cervical erosion has completed
Rehabilitation, the immunologic function of vagina is significantly improved, and 95% subject with III degree of cervical erosion repairs degree and reaches trouble
Level before sick.
The overall experience of all subjects：Using cervical erosion can be repaired after complexing agent dressing of the present invention, increase vagina
Immunity, remold body, improve skin quality, eliminate dark sore, acne, desalinate color spot, reduce wrinkle etc..
Embodiment 2
A kind of medical chitosan oligosaccharide complexing agent dressing, including the following substances counted by weight：9 parts of phellodendron extract, Pu
Yellow 5 parts of extract, 6 parts of licorice, 8 parts of Realgar extract, 6 parts of mint extract, 5 parts of Radix Gentianae extract, indigo naturalis are carried
Take 5 parts of thing, 3 parts of borneol, 5 parts of gypsum, 7 parts of pearl powder, 8 parts of calamine, 8 parts of alumen, 15 parts of chitosan.
Said composition preparation method and application process are same as Example 1.
By the complexing agent dressing of embodiment 2 be used for 100 with cervical erosion subjects (cervical erosion be divided into I degree-compared with
Gently；II degree-heavier；III degree-serious).
After complexing agent dressing of the present invention three days：For pudendal pruritus caused by cervical erosion unbearably, leucorrhea increasing, evil
The symptom such as dew is not net, peculiar smell, the soreness of waist stomachache, uterus are touched a tender spot, with obvious inhibitory action, 80% with cervical erosion by
Examination person part is improved.
After complexing agent dressing of the present invention seven days：80% subject with cervical erosion starts to scab.
After complexing agent dressing of the present invention 15 days：80% subject with cervical erosion is initially located in growth shape
State.
After complexing agent dressing of the present invention 30 days：98% subject with I degree of cervical erosion repairs degree and is averaged
Level before illness is reached, 90% subject with II degree of cervical erosion repairs degree and averagely reaches more than 75%, and 90% suffers from
The subject of III degree of cervical erosion repairs degree and averagely reaches more than 60%.
After complexing agent dressing of the present invention 45 days：98% subject with I degree of cervical erosion is also complete
The level before illness is reached, and the immunologic function of vagina is improved, and 80% subject with II degree of cervical erosion repaiies
Multiple degree averagely reaches level before illness.
After complexing agent dressing of the present invention 60 days：98% subject with I degree of II degree of cervical erosion has completed
Rehabilitation, the immunologic function of vagina is significantly improved, and 95% subject with III degree of cervical erosion repairs degree and reaches trouble
Level before sick.
The overall experience of all subjects：Using cervical erosion can be repaired after complexing agent dressing of the present invention, increase vagina
Immunity, remold body, improve skin quality, eliminate dark sore, acne, desalinate color spot, reduce wrinkle etc..
Embodiment 3
A kind of medical chitosan oligosaccharide complexing agent dressing, including the following substances counted by weight：7 parts of phellodendron extract, Pu
Yellow 4 parts of extract, 6 parts of licorice, 7 parts of Realgar extract, 4 parts of mint extract, 4 parts of Radix Gentianae extract, indigo naturalis are carried
Take 4 parts of thing, 2 parts of borneol, 4 parts of gypsum, 6 parts of pearl powder, 7 parts of calamine, 6 parts of alumen, 13 parts of chitosan.
The preparation method and application method of said composition is same as Example 1.
By the complexing agent dressing of embodiment 3 be used for 100 with cervical erosion subjects (cervical erosion be divided into I degree-compared with
Gently；II degree-heavier；III degree-serious).
After complexing agent dressing of the present invention three days：For pudendal pruritus caused by cervical erosion unbearably, leucorrhea increasing, evil
The symptom such as dew is not net, peculiar smell, the soreness of waist stomachache, uterus are touched a tender spot, with obvious inhibitory action, 80% with cervical erosion by
Examination person part is improved.
After complexing agent dressing of the present invention seven days：80% subject with cervical erosion starts to scab.
After complexing agent dressing of the present invention 15 days：80% subject with cervical erosion is initially located in growth shape
State.
After complexing agent dressing of the present invention 30 days：98% subject with I degree of cervical erosion repairs degree and is averaged
Level before illness is reached, 90% subject with II degree of cervical erosion repairs degree and averagely reaches more than 75%, and 90% suffers from
The subject of III degree of cervical erosion repairs degree and averagely reaches more than 60%.
After complexing agent dressing of the present invention 45 days：98% subject with I degree of cervical erosion is also complete
The level before illness is reached, and the immunologic function of vagina is improved, and 80% subject with II degree of cervical erosion repaiies
Multiple degree averagely reaches level before illness.
After complexing agent dressing of the present invention 60 days：98% subject with I degree of II degree of cervical erosion has completed
Rehabilitation, the immunologic function of vagina is significantly improved, and 95% subject with III degree of cervical erosion repairs degree and reaches trouble
Level before sick.
Wherein, embodiment 3 is more gently, non-stimulated compared to embodiment 1 and embodiment 2, is optimum implementation.
As described above, only the preferred embodiments of the invention, when the scope of implementation of the invention can not be limited with this,
I.e. generally according to simple equivalent changes and modifications made by the content described in the claims in the present invention and description of the invention, all still
Belong within the claims in the present invention scope.In addition, summary part and title, which are intended merely to auxiliary patent document, searches it
With not for limiting the interest field of the present invention.
Claims (9)
1. a kind of medical chitosan oligosaccharide complexing agent dressing, it is characterised in that the dressing includes the following substances counted by weight：Should
Medical chitosan oligosaccharide complexing agent dressing includes the following substances counted by weight：6-9 parts of phellodendron extract, Pollen Tyjphae extract 3-5
Part, 5-6 parts of licorice, 6-8 parts of Realgar extract, 2-6 parts of mint extract, 3-5 parts of Radix Gentianae extract, indigo naturalis are extracted
3-5 parts of thing, 1-3 parts of borneol, 3-5 parts of gypsum, 4-7 parts of pearl powder, 5-8 parts of alumen of 6-8 parts of calamine, 10-15 parts of chitosan.
2. medical chitosan oligosaccharide complexing agent dressing as claimed in claim 1, it is characterised in that medical chitosan oligosaccharide complexing agent dressing
Each material does following proportioning according to parts by weight：7 parts of phellodendron extract, 4 parts of Pollen Tyjphae extract, 6 parts of licorice, realgar carry
Take 7 parts of thing, 4 parts of mint extract, 4 parts of Radix Gentianae extract, 4 parts of Indigo Naturalis extract, 2 parts of borneol, 4 parts of gypsum, pearl powder 6
Part, 7 parts of calamine, 6 parts of alumen, 13 parts of chitosan.
3. medical chitosan oligosaccharide complexing agent dressing as claimed in claim 1, it is characterised in that the phellodendron extract, cattail pollen carry
It is overcritical titanium dioxide to take thing, licorice, Realgar extract, mint extract, Radix Gentianae extract and Indigo Naturalis extract
Carbon extraction is formed.
4. medical chitosan oligosaccharide complexing agent dressing as claimed in claim 1, it is characterised in that the borneol, gypsum and pearl
Powder is powder.
5. medical chitosan oligosaccharide complexing agent dressing as claimed in claim 1, it is characterised in that the calamine is white skilled 9 times
The too quickly cannon system of vinegar is formed, and the alumen is that boiling water boiling is formed.
6. the application in cervical erosion is repaired in any one of the claim 1-5 medical chitosan oligosaccharide complexing agent dressing, its feature exists
In by the medical chitosan oligosaccharide complexing agent dressing described in claim any one of 1-5 in vagina.
7. the application in cervical erosion, its feature are repaired in medical chitosan oligosaccharide complexing agent dressing as described in claim any one of 1-5
It is, its application process is：Medical chitosan oligosaccharide complexing agent dressing is directly applied into intravaginal.
8. the application in cervical erosion, its feature are repaired in medical chitosan oligosaccharide complexing agent dressing as described in claim any one of 1-5
It is, its concrete application method is：Vagina and uterine neck secretions are first cleaned with 0.1% anti-inflammation liquid, then medicaments uniformity are applied
In affected part.
9. a kind of method of the medical chitosan oligosaccharide complexing agent dressing prepared as described in claim 1-5, it is characterised in that described to apply
The preparation of material is according to following processing step：Phellodendron extract, Pollen Tyjphae extract, licorice, realgar is weighed in proportion to extract
Thing, mint extract, Radix Gentianae extract, Indigo Naturalis extract, borneol, gypsum, pearl powder, calamine, alumen, are placed in stirring
8~12min is stirred in device, chitosan is added after mixing, is again stirring for 5~10min, bottling is well mixed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710318380.7A CN107233446A (en) | 2017-05-08 | 2017-05-08 | A kind of medical chitosan oligosaccharide complexing agent dressing and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710318380.7A CN107233446A (en) | 2017-05-08 | 2017-05-08 | A kind of medical chitosan oligosaccharide complexing agent dressing and preparation method thereof |
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| CN107233446A true CN107233446A (en) | 2017-10-10 |
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| CN201710318380.7A Pending CN107233446A (en) | 2017-05-08 | 2017-05-08 | A kind of medical chitosan oligosaccharide complexing agent dressing and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110448580A (en) * | 2019-06-19 | 2019-11-15 | 郭蓉 | A kind of ointment and preparation method thereof for holding back humidogene flesh |
-
2017
- 2017-05-08 CN CN201710318380.7A patent/CN107233446A/en active Pending
Non-Patent Citations (4)
| Title |
|---|
| 张力群等: "《中国民族民间药物外治大全》", 31 January 1997, 山西科学技术出版社 * |
| 张慧珍: "壳聚糖妇科凝胶对宫颈糜烂的疗效评价", 《实用妇科内分泌杂志》 * |
| 曾宪策: "《临床常用中药400种》", 30 June 2012, 重庆出版社 * |
| 龙世青: "养阴生肌散治疗宫颈糜烂30例疗效观察", 《江西中医药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110448580A (en) * | 2019-06-19 | 2019-11-15 | 郭蓉 | A kind of ointment and preparation method thereof for holding back humidogene flesh |
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