CN107184753A - A kind of Camellia nitidissima antiallergy bagged instant preparation and preparation method thereof - Google Patents

A kind of Camellia nitidissima antiallergy bagged instant preparation and preparation method thereof Download PDF

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CN107184753A
CN107184753A CN201710332828.0A CN201710332828A CN107184753A CN 107184753 A CN107184753 A CN 107184753A CN 201710332828 A CN201710332828 A CN 201710332828A CN 107184753 A CN107184753 A CN 107184753A
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parts
preparation
camellia nitidissima
bagged instant
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于大永
宋昱
史丽颖
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Dalian University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to tcm field, more particularly to a kind of Camellia nitidissima antiallergy bagged instant preparation and preparation method thereof.The Camellia nitidissima antiallergy bagged instant preparation includes following traditional Chinese medicinal components:20~25 parts of golden flower tea peels, 10~15 parts of Asian puccoon, 10~15 parts of madder, 10~15 parts of eclipta, 5~10 parts of calamus, 5~10 parts of the dried rhizome of rehmannia, 5~10 parts of the flower bud of lily magnolia;Present invention also offers the preparation method of the Camellia nitidissima antiallergy bagged instant preparation; raw material components are obtained into coarse granule by baking, crushing, sieving; then various medicinal material coarse granules are well mixed, dry sterilization, last quantitative separating is in being made Camellia nitidissima antiallergy bagged instant preparation in filter paper bag.The present invention has effectively played the antianaphylactic medicinal effects of golden flower tea peels by the reasonable compatibility of plurality of Chinese, and Camellia nitidissima antiallergy bagged instant preparation is made, and safety non-toxic is made bagged instant preparation form, carried and easy to use.

Description

A kind of Camellia nitidissima antiallergy bagged instant preparation and preparation method thereof
Technical field
The present invention relates to tcm field, more particularly to a kind of Camellia nitidissima antiallergy bagged instant preparation and preparation method thereof.
Background technology
Anaphylactia mainly includes:Eczema, allergic dermatitis, allergic conjunctivitis, enteritis anaphylactica, allergia nose Inflammation, allergic asthma (abbreviation asthma) etc..These anaphylactias can individualism, also mutually and can deposit and cause multisystem mistake It is quick.Many epidemiological investigations confirm that in recent years, the incidence of disease of anaphylactia constantly rises in the world, As very noticeable social concern, wherein climbing highest is allergic asthma and allergic rhinitis.Not only give day Often life brings inconvenience, causes mental suffering, reduction quality of life, and the duration is long, and what is had turns into obstinate disease, Also having causes died.
Camellia nitidissima, is all Theaceae Camellia Plants with tea, South Mountain tea, camellia, oil tea etc., Camellia nitidissima is using its petal as Huang Color and it is famous, vegetable formal name is Camellia chrysantha (Hu) Tuyama, is Theaceae, Camellia, and evergreen shrubs is to small Arbor.The nontoxic level of golden flower Camellias, containing more than 400 kinds of nutriments, have no toxic side effect.Rich in tea polysaccharide, Tea Polyphenols, Total saponin, General flavone, Tea Pigment, caffeine, protein, vitamin B1, B2, vitamin C, vitamin E, folic acid, aliphatic acid, B- carrotene Etc. a variety of natural nutrition compositions;Camellia nitidissima contains tens kinds of amino acid such as theanine, threonine, and a variety of to human body rich in having The trace elements such as natural organic germanium (Ge), selenium (Se), molybdenum (Mo), zinc (Zn), vanadium (V) with important health-care effect, and potassium (K), the macroelement such as calcium (Ca), magnesium (Mg).Clinical research shows that Camellia nitidissima, which has, suppresses tumour, strengthens immunity of organism, anti-ageing Always, the various physiological functions of balanced human, hypotensive, enhancing blood vessel elasticity and myocardial contractive power, enhancing liver metabolism, with And the effect such as various enzymes in human activin.Wang Yong very wait experiments prove that golden flower tea peels have antianaphylaxis (Wang Yongqi, The anti-anaphylactoid screening active ingredients of IgE mediating type Is of Camellia Section Chrysanthas, [J], Central-South pharmacy, 7 (10) are waited before Peng Xiao, Tang: 721-724.).At present, on Camellia nitidissima, especially its plant pericarp is less for the document for treating antiallergy disease, to golden flower The antiallergy research of tea peel is deep not enough.
Asian puccoon, cold in nature, sweet, salty, the thoughts of returning home, Liver Channel.Cure mainly trusted subordinate's perverse trend, five subcutaneous ulcers, tonifying middle-Jiao and Qi, sharp nine orifices, waterway.
Madder, it is cold in nature enter blood system, can cooling blood and hemostasis, and can stagnation resolvation.
Eclipta, property is sweet, acid, trembles with fear.Return kidney, Liver Channel.Have nourishing liver and kidney, the effect of cooling blood and hemostasis.
Calamus, property is bitter, pungent, temperature.There is resolving sputum, have one's ideas straightened out, invigorating the spleen, the effect of dampness removing.
The dried rhizome of rehmannia, alias glutinous rehmannia, marrow, positive essence, benzyl root etc., have heat-clearing, promote the production of body fluid, moisturize, laxation, broken stasis of blood, it is raw it is new, relieve pain, The effect of menstruation regulating, the metal-inflicted wound stasis of blood, cool blood, hemostasis.
The flower bud of lily magnolia, also known as lily magnolia, purple yu-lan (Magnolia liliflora), property are pungent, temperature, attach to the lung and stomach meridians.There is the effect of expelling cold, eliminating, clearing the nasal passage.
At present, the product using Camellia nitidissima as raw material is mostly common with drink, it is impossible to meets the demand of people, wastes golden flower The medicine resource of tea especially golden flower tea peels.
The content of the invention
It is an object of the invention to overcome the defect of problem above there is provided a kind of to be used to treating contact dermatitis, eczema Camellia nitidissima antiallergy bagged instant preparation.
The purpose of the present invention can be achieved through the following technical solutions:
A kind of Camellia nitidissima antiallergy bagged instant preparation, includes the raw material components of following parts by weight:
20~25 parts of golden flower tea peels, 10~15 parts of Asian puccoon, 10~15 parts of madder, 10~15 parts of eclipta, calamus 5~10 Part, 5~10 parts of the dried rhizome of rehmannia, 5~10 parts of the flower bud of lily magnolia.
A kind of above-mentioned Camellia nitidissima antiallergy bagged instant preparation, includes the raw material components of following parts by weight:20 parts of golden flower tea peels, 12 parts of Asian puccoon, 12 parts of madder, 12 parts of eclipta, 5 parts of calamus, 5 parts of the dried rhizome of rehmannia, 5 parts of the flower bud of lily magnolia.
A kind of preparation method of above-mentioned Camellia nitidissima antiallergy bagged instant preparation, comprises the following steps:
(1) golden flower tea peels, Asian puccoon, madder, eclipta, calamus, the dried rhizome of rehmannia and the flower bud of lily magnolia are rinsed respectively, dedusting, dry after Baking, crosses 10~40 mesh sieves after crushing respectively, obtains coarse granule;
(2) coarse granule obtained in step (1) is well mixed by proportioning, quantitative separating is in filter paper bag after dry sterilization It is interior, produce Camellia nitidissima antiallergy bagged instant preparation.
The temperature of baking is 60 DEG C in a kind of preparation method of above-mentioned Camellia nitidissima antiallergy bagged instant preparation, step (1), baking Time is 1h.
A kind of preparation method of above-mentioned Camellia nitidissima antiallergy bagged instant preparation, the quality of every bag of Camellia nitidissima bagged instant preparation for 65~ 100g。
Application method:Camellia nitidissima antiallergy bagged instant preparation is put into 2~3L water and soaked 15~20 minutes, heating is boiled hereinafter Fried 25~the 40min of fire, then removes dregs of a decoction bag, treats that water temperature is down to 35~40 DEG C, smoked to wash 15~20min of affected part, smoked daily to wash 1 ~3 times.
The method have the advantages that:
1. the present invention has effectively played the antianaphylactic medicinal effect of golden flower tea peels by the reasonable compatibility of plurality of Chinese Really, Camellia nitidissima antiallergy bagged instant preparation is made, contact dermatitis, eczema can be treated, and have no toxic side effect.
2. bagged instant preparation form is made in the present invention, technique is simple, applied widely, and Chinese medicine, which is decocted, to be carried fully, dregs of a decoction convenient separation, Carry and easy to use.
Embodiment
Below in conjunction with specific embodiment, the present invention will be further described.
Embodiment 1
A kind of Camellia nitidissima antiallergy bagged instant preparation, includes the raw material components of following parts by weight:Golden flower tea peels 20g, Asian puccoon 15g, madder 10g, eclipta 10g, calamus 10g, dried rhizome of rehmannia 5g, flower bud of lily magnolia 5g.
A kind of preparation method of above-mentioned Camellia nitidissima antiallergy bagged instant preparation, comprises the following steps:
(1) by golden flower tea peels, Asian puccoon, madder, eclipta, calamus, the dried rhizome of rehmannia, flower bud of lily magnolia rinsing, dedusting, dry after at 60 DEG C 1h is toasted, 20 mesh sieves were crushed respectively and obtain coarse granule;
(2) golden flower tea peels 20g, Asian puccoon 15g, madder 10g, eclipta 10g, calamus 10g, dried rhizome of rehmannia 5g, the flower bud of lily magnolia are weighed again 5g, is well mixed, dry sterilization is sub-packed in filter paper bag, produces bagged instant preparation.
Above-mentioned Camellia nitidissima antiallergy bagged instant preparation is put into 2L water and soaked 15 minutes, the fried 30min of rear slow fire is boiled in heating, Then dregs of a decoction bag is removed, treats that water temperature is down to 40 DEG C, smoked to wash affected part 20min, daily smoke is washed 2 times.
Embodiment 2
A kind of Camellia nitidissima antiallergy bagged instant preparation, includes the raw material components of following parts by weight:Golden flower tea peels 20g, Asian puccoon 10g, madder 15g, eclipta 10g, calamus 5g, dried rhizome of rehmannia 5g, flower bud of lily magnolia 10g.
A kind of preparation method of above-mentioned Camellia nitidissima antiallergy bagged instant preparation, comprises the following steps:
(1) by golden flower tea peels, Asian puccoon, madder, eclipta, calamus, the dried rhizome of rehmannia, flower bud of lily magnolia rinsing, dedusting, dry after at 60 DEG C 1h is toasted, 30 mesh sieves were crushed respectively and obtain coarse granule,
(2) golden flower tea peels 20g, Asian puccoon 10g, madder 15g, eclipta 10g, calamus 5g, dried rhizome of rehmannia 5g, flower bud of lily magnolia 10g are weighed, Well mixed, dry sterilization is sub-packed in filter paper bag, produces Camellia nitidissima antiallergy bagged instant preparation.
Above-mentioned Camellia nitidissima antiallergy bagged instant preparation is put into 2L water and soaked 20 minutes, the fried 25min of rear slow fire is boiled in heating, Then dregs of a decoction bag is removed, treats that water temperature is down to 35 DEG C, smoked to wash affected part 15min, daily smoke is washed 3 times.
Embodiment 3
A kind of Camellia nitidissima antiallergy bagged instant preparation, includes the raw material components of following parts by weight:Golden flower tea peels 25g, Asian puccoon 10g, madder 10g, eclipta 15g, calamus 10g, dried rhizome of rehmannia 10g, flower bud of lily magnolia 5g.
A kind of preparation method of above-mentioned Camellia nitidissima antiallergy bagged instant preparation, comprises the following steps:
(1) by golden flower tea peels, Asian puccoon, madder, eclipta, calamus, the dried rhizome of rehmannia, the rinsing of flower bud of lily magnolia composition, dedusting, dry after 1h is toasted at 60 DEG C, 10 mesh sieves were crushed respectively and obtain coarse granule;
(2) golden flower tea peels 25g, Asian puccoon 10g, madder 10g, eclipta 15g, calamus 10g, dried rhizome of rehmannia 10g, the flower bud of lily magnolia are weighed 5g, is well mixed, dry sterilization is sub-packed in filter paper bag, produces bagged instant preparation.
Above-mentioned Camellia nitidissima antiallergy bagged instant preparation is put into 2L water and soaked 15 minutes, the fried 30min of rear slow fire is boiled in heating, Then dregs of a decoction bag is removed, treats that water temperature is down to 35 DEG C, smoked to wash affected part 20min, daily smoke is washed 2 times.
Embodiment 4
A kind of Camellia nitidissima antiallergy bagged instant preparation, includes the raw material components of following parts by weight:Golden flower tea peels 25g, Asian puccoon 15g, madder 15g, eclipta 10g, calamus 5g, dried rhizome of rehmannia 10g, flower bud of lily magnolia 10g.
A kind of preparation method of above-mentioned Camellia nitidissima antiallergy bagged instant preparation, comprises the following steps:
(1) by golden flower tea peels, Asian puccoon, madder, eclipta, calamus, the dried rhizome of rehmannia, flower bud of lily magnolia rinsing, dedusting, dry after at 60 DEG C 1h is toasted, 40 mesh sieves were crushed respectively and obtain coarse granule;
(2) golden flower tea peels 25g, Asian puccoon 15g, madder 15g, eclipta 10g, calamus 5g, dried rhizome of rehmannia 10g, the flower bud of lily magnolia are weighed 10g, is well mixed, dry sterilization is sub-packed in filter paper bag, produces bagged instant preparation.
Above-mentioned Camellia nitidissima antiallergy bagged instant preparation is put into 3L water and soaked 20 minutes, the fried 40min of rear slow fire is boiled in heating, Then dregs of a decoction bag is removed, treats that water temperature is down to 40 DEG C, smoked to wash affected part 20min, daily smoke is washed 1 time.
Conditioning for anaphylactia state improves clinical observation statistics:
1st, case is chosen:Clinically choose the anaphylactia patient 100 made a definite diagnosis, 20~50 years old age, male 60, Women 40, is divided into four groups of experimental groups 1~4, every group 25.
2nd, experimental method:Give experimental group 1~4 respectively using the embodiment of the present invention 1~4 prepare bagged instant preparation, respectively according to The embodiment of embodiment 1~4 is implemented, continuous to use one month, observes and record the recovery situation of patient.
3rd, curative effect determinate standard:Effectively:Anaphylactia clinical symptom disappearance, every sign recovers normal, in half a year not See recurrence;It is effective:Anaphylactia clinical symptoms improve, and the performance of each sign is clearly better before patient compares medication;It is invalid:Disease Feelings are without any improvement or aggravate.
4th, experimental data is counted:
Classification Case load Effectively It is effective It is invalid Adverse reaction It is efficient
Embodiment 1 25 15 9 1 0 96.0
Embodiment 2 25 18 7 0 0 100.0
Embodiment 3 25 14 11 0 0 100.0
Embodiment 4 25 10 13 2 0 92.0
5th, experimental result:As can be seen from the above experimental data, the Camellia nitidissima antiallergy bagged instant preparation for preparing of the present invention for The total effective rate of the treatment of anaphylactia is 97%, and 100 patients have no any adverse reaction, therefore explanation, the present invention Camellia nitidissima antiallergy bagged instant preparation be treat anaphylactia safe and effective medicine, with good clinical expansion meaning.

Claims (5)

1. a kind of Camellia nitidissima antiallergy bagged instant preparation, it is characterised in that include the raw material components of following parts by weight:
20~25 parts of golden flower tea peels, 10~15 parts of Asian puccoon, 10~15 parts of madder, 10~15 parts of eclipta, 5~10 parts of calamus, 5~10 parts of the dried rhizome of rehmannia, 5~10 parts of the flower bud of lily magnolia.
2. a kind of Camellia nitidissima antiallergy bagged instant preparation as claimed in claim 1, it is characterised in that include the raw material of following parts by weight Component:20 parts of golden flower tea peels, 12 parts of Asian puccoon, 12 parts of madder, 12 parts of eclipta, 5 parts of calamus, 5 parts of the dried rhizome of rehmannia, 5 parts of the flower bud of lily magnolia.
3. a kind of preparation method of Camellia nitidissima antiallergy bagged instant preparation as claimed in claim 1, it is characterised in that including following step Suddenly:
(1) golden flower tea peels, Asian puccoon, madder, eclipta, calamus, the dried rhizome of rehmannia and the flower bud of lily magnolia are rinsed respectively, dedusting, dry after toast, 10~40 mesh sieves are crossed after crushing respectively, coarse granule is obtained;
(2) coarse granule that be obtained in step (1) is well mixed by proportioning, quantitative separating is in filter paper bag after dry sterilization, i.e., Obtain Camellia nitidissima antiallergy bagged instant preparation.
4. the preparation method of Camellia nitidissima antiallergy bagged instant preparation as claimed in claim 3, it is characterised in that baking temperature is 60 DEG C, baking time is 1h.
5. the preparation method of Camellia nitidissima antiallergy bagged instant preparation as claimed in claim 3, it is characterised in that the matter of every bag of bagged instant preparation Measure as 65~100g.
CN201710332828.0A 2017-05-12 2017-05-12 A kind of Camellia nitidissima antiallergy bagged instant preparation and preparation method thereof Pending CN107184753A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102106420A (en) * 2009-12-24 2011-06-29 防城港市百喜金花茶科技开发有限公司 Method for processing camellia nitidissima granules

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102106420A (en) * 2009-12-24 2011-06-29 防城港市百喜金花茶科技开发有限公司 Method for processing camellia nitidissima granules

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
周爱珍: ""三草汤与强的松治疗单纯性过敏性紫癜41例效果观察", 《南通医学院学报》 *
王永奇等: "金花茶组植物抗lgE介导1型过敏反应的活性筛选", 《中南药学》 *

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Application publication date: 20170922