CN107184737A - It is a kind of to treat Camellia nitidissima bagged instant preparation of anaphylactia and preparation method thereof - Google Patents

It is a kind of to treat Camellia nitidissima bagged instant preparation of anaphylactia and preparation method thereof Download PDF

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CN107184737A
CN107184737A CN201710332827.6A CN201710332827A CN107184737A CN 107184737 A CN107184737 A CN 107184737A CN 201710332827 A CN201710332827 A CN 201710332827A CN 107184737 A CN107184737 A CN 107184737A
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parts
preparation
camellia nitidissima
bagged instant
instant preparation
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于大永
宋昱
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Dalian University
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Dalian University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The present invention relates to tcm field, more particularly to a kind of treat Camellia nitidissima bagged instant preparation of anaphylactia and preparation method thereof.The Camellia nitidissima bagged instant preparation is obtained by following Chinese medicine composition by weight:Golden flower tea peels 15~30, Asian puccoon 5~15, madder 5~15, eclipta 5~15, the root of Dahurain angelica 3~8, chrysanthemum 3~8, the root of kudzu vine 4~14.Present invention also offers the preparation method of the bagged instant preparation, above-mentioned raw materials are rinsed, dedusting, dried, after drying, by Asian puccoon, madder, eclipta, chrysanthemum co-grinding into fine powder, it is allowed to be absorbed in fine powder after remaining medicinal material extract concoction, well mixed, last quantitative separating is in the Camellia nitidissima bagged instant preparation that treatment anaphylactia is made in filter paper bag.The present invention has effectively played the antianaphylactic medicinal effects of golden flower tea peels by the reasonable compatibility of plurality of Chinese, and Camellia nitidissima antiallergy bagged instant preparation is made, and safety non-toxic is made bagged instant preparation form, carried and easy to use.

Description

It is a kind of to treat Camellia nitidissima bagged instant preparation of anaphylactia and preparation method thereof
Technical field
The present invention relates to tcm field, more particularly to a kind of Camellia nitidissima bagged instant preparation for treating anaphylactia and its preparation Method.
Background technology
Anaphylactia mainly includes:Eczema, allergic dermatitis, allergic conjunctivitis, enteritis anaphylactica, allergia nose Inflammation, allergic asthma (abbreviation asthma) etc..These anaphylactias can individualism, also mutually and can deposit and cause multisystem mistake It is quick.Many epidemiological investigations confirm that in recent years, the incidence of disease of anaphylactia constantly rises in the world, As very noticeable social concern, wherein climbing highest is allergic asthma and allergic rhinitis.Not only give day Often life brings inconvenience, causes mental suffering, reduction quality of life, and the duration is long, and what is had turns into obstinate disease, Also having causes died.
Camellia nitidissima, is all Theaceae Camellia Plants with tea, South Mountain tea, camellia, oil tea etc., Camellia nitidissima is using its petal as Huang Color and it is famous, vegetable formal name is Camellia chrysantha (Hu) Tuyama, is Theaceae, Camellia, and evergreen shrubs is to small Arbor.The nontoxic level of golden flower Camellias, containing more than 400 kinds of nutriments, have no toxic side effect.Rich in tea polysaccharide, Tea Polyphenols, Total saponin, General flavone, Tea Pigment, caffeine, protein, vitamin B1, B2, vitamin C, vitamin E, folic acid, aliphatic acid, B- carrotene Etc. a variety of natural nutrition compositions;Camellia nitidissima contains tens kinds of amino acid such as theanine, threonine, and a variety of to human body rich in having The trace elements such as natural organic germanium (Ge), selenium (Se), molybdenum (Mo), zinc (Zn), vanadium (V) with important health-care effect, and potassium (K), the macroelement such as calcium (Ca), magnesium (Mg).Clinical research shows that Camellia nitidissima, which has, suppresses tumour, strengthens immunity of organism, anti-ageing Always, the various physiological functions of balanced human, hypotensive, enhancing blood vessel elasticity and myocardial contractive power, enhancing liver metabolism, with And the effect such as various enzymes in human activin.Wang Yong very wait experiments prove that golden flower tea peels have antianaphylaxis (Wang Yongqi, The anti-anaphylactoid screening active ingredients of IgE mediating type Is of Camellia Section Chrysanthas, [J], Central-South pharmacy, 7 (10) are waited before Peng Xiao, Tang: 721-724.).At present, on Camellia nitidissima, especially its plant pericarp is less for the document for treating antiallergy disease, to golden flower The antiallergy research of tea peel is deep not enough.
Asian puccoon, cold in nature, sweet, salty, the thoughts of returning home, Liver Channel.Cure mainly trusted subordinate's perverse trend, five subcutaneous ulcers, tonifying middle-Jiao and Qi, sharp nine orifices, waterway.
Madder, it is cold in nature enter blood system, can cooling blood and hemostasis, and can stagnation resolvation.
Eclipta, property is sweet, acid, trembles with fear.Return kidney, Liver Channel.Have nourishing liver and kidney, the effect of cooling blood and hemostasis.
The root of Dahurain angelica, warm-natured, pungent, gas fragrance, slight bitter.The effect of having wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving.
Chrysanthemum, property is sweet, be slightly cold, and has effects that dissipate wind-heat, flat liver improving eyesight, disappears and cough analgesic.
The root of kudzu vine, it is cool in nature, it is sweet, pungent.There is expelling pathogenic factors from muscles and skin to bring down a fever, promoting eruption promotes the production of body fluid to quench thirst, the work(of Shengyang Zhixie.
At present, the product using Camellia nitidissima as raw material is mostly common with drink, it is impossible to meets the demand of people, wastes golden flower The medicine resource of tea especially golden flower tea peels.
The content of the invention
It is an object of the invention to overcome the defect of problem above there is provided a kind of to be used to treating contact dermatitis, eczema Camellia nitidissima bagged instant preparation.
The purpose of the present invention is achieved through the following technical solutions:
A kind of Camellia nitidissima bagged instant preparation for treating anaphylactia, in parts by weight, by 40~60 parts of suction juice medicinal material and 40 ~60 parts of decoction liquor medicinal material is formulated;Wherein, inhaling juice medicinal material includes the raw material components of following parts by weight:5~15 parts of Asian puccoon, 5~15 parts of madder, 5~15 parts of eclipta, 3~8 parts of chrysanthemum;Decoction liquor medicinal material includes the raw material components of following parts by weight:Golden flower 15~30 parts of tea peel, 3~8 parts of the root of Dahurain angelica, 4~14 parts of the root of kudzu vine.
A kind of above-mentioned Camellia nitidissima bagged instant preparation for treating anaphylactia, the suction juice medicinal material, in parts by weight, including purple 5 parts of 10 parts of grass, 10 parts of madder, 10 parts of eclipta and chrysanthemum.
A kind of above-mentioned Camellia nitidissima bagged instant preparation for treating anaphylactia, the decoction liquor medicinal material, in parts by weight, including 10 parts of 20 parts of golden flower tea peels, 7 parts of the root of Dahurain angelica and the root of kudzu vine.
A kind of preparation method of above-mentioned Camellia nitidissima bagged instant preparation for treating anaphylactia, comprises the following steps:
(1) each component raw material is weighed by proportioning, is dried after rinsing, it is stand-by;
(2) crushing of juice medicinal material is inhaled:Fine powder, mistake are ground into after Asian puccoon after drying, madder, eclipta, chrysanthemum are mixed 10~40 mesh sieves, obtain inhaling juice fine powder;
(3) extraction of decoction liquor:Coarse powder is ground into after golden flower tea peels after drying, the root of Dahurain angelica, the root of kudzu vine are mixed, plus 10~ 20 times of water, soaks 10~20min, decocts and extracts 1~3 time, and decocting time is 1~3h, merges decoction liquor, is obtained most after filtering Whole decoction liquor;
(4) concentrate:The relative density that the decoction liquor of gained in step (3) is concentrated by evaporation into relative to water is 1.2~1.4 Thick paste;
(5) mix:Thick paste obtained by step (4) is well mixed with inhaling juice fine powder obtained by step (2), treats that thick paste is thin to inhaling juice After powder absorption completely, it is dried, obtains dried powder;
(6) particle is prepared:The ethanol of addition 50%~60% in the dried powder obtained by step (5), carries out wet method system Grain, obtained particle is crossed after 10~20 mesh sieves, dry sterilization, and quantitative separating is in filter paper bag, producing Camellia nitidissima bagged instant preparation.
The temperature of drying in a kind of preparation method of above-mentioned Camellia nitidissima bagged instant preparation for treating anaphylactia, step (1) For 100 DEG C, drying time is 2h.
Filtering in a kind of preparation method of above-mentioned Camellia nitidissima bagged instant preparation for treating anaphylactia, step (3) is to use 4 Layer gauze is filtered, and gauze used is 15 mesh gauzes.
The temperature dried in a kind of preparation method of upper described Camellia nitidissima bagged instant preparation for treating anaphylactia, step (5) Spend for 65 DEG C.
A kind of preparation method of above-mentioned Camellia nitidissima bagged instant preparation for treating anaphylactia, the quality of every bag of bagged instant preparation is 65 ~100g.
Application method:The Camellia nitidissima bagged instant preparation for treating anaphylactia is put into 2~3L water and soaked 15~30 minutes, plus Heat boils the fried 25~40min of rear slow fire, then removes dregs of a decoction bag, treats that water temperature is down to 35~40 DEG C, it is smoked wash affected part 10~ 20min, daily smoke is washed 1~3 time.
The method have the advantages that:
1. the present invention has effectively played the antianaphylactic medicinal effect of golden flower tea peels by the reasonable compatibility of plurality of Chinese Really, Camellia nitidissima antiallergy bagged instant preparation is made, contact dermatitis, eczema can be treated, and have no toxic side effect.
2. bagged instant preparation form is made in the present invention, technique is simple, applied widely, and Chinese medicine, which is decocted, to be carried fully, dregs of a decoction convenient separation, Carry and easy to use.
Embodiment
Below in conjunction with specific embodiment, the present invention will be further described.
Embodiment 1
A kind of Camellia nitidissima bagged instant preparation for treating anaphylactia, includes the raw material of following parts by weight:Asian puccoon 5g, madder 5g, Eclipta 10g, chrysanthemum 5g, golden flower tea peel 20g, root of Dahurain angelica 7g, root of kudzu vine 13g.
A kind of preparation method of above-mentioned Camellia nitidissima bagged instant preparation for treating anaphylactia, comprises the following steps:
(1) each component raw material is weighed by weight ratio, and 2h is dried at 100 DEG C after rinsing, it is stand-by;
(2) crushing of juice medicinal material is inhaled:It is ground into after the Asian puccoon 5g weighed up, madder 5g, eclipta 10g, chrysanthemum 5g are mixed Fine powder, crosses 20 mesh sieves, obtains inhaling juice fine powder;
(3) extraction of decoction liquor:Coarse powder is ground into after the golden flower tea peels 20g weighed up, root of Dahurain angelica 7g, root of kudzu vine 13g are mixed, Plus 20 times of water, 10min is soaked, decocts and extracts 3 times, decocting time is 3h+2h+1h, merges decoction liquor, with the yarn of 4 layer of 15 mesh Cloth is filtered, and final decoction liquor is obtained after filtering;
(4) concentrate:By the decoction liquor of gained in step (3) be concentrated by evaporation into the relative density relative to water for 1.2 it is thick Cream;
(5) mix:Thick paste obtained by step (4) is well mixed with inhaling juice fine powder obtained by step (2), treats that thick paste is thin to inhaling juice After powder absorption completely, 65 DEG C are dried, and obtain dried powder,;
(6) particle is prepared:The ethanol of addition 55% in dried powder obtained by step (5), carries out wet granulation, will be made Particle is crossed after 20 mesh sieves, dry sterilization, is sub-packed in filter paper bag, produces Camellia nitidissima bagged instant preparation;
The Camellia nitidissima bagged instant preparation of above-mentioned treatment anaphylactia is put into 2L water and soaks 30min, rear slow fire is boiled in heating Fried 20min, then removes dregs of a decoction bag, treats that water temperature is down to 35 DEG C, smoked to wash affected part 15min, and daily smoke is washed 3 times.
Embodiment 2
A kind of Camellia nitidissima bagged instant preparation for treating anaphylactia, includes the raw material of following parts by weight:Asian puccoon 5g, madder 10g, Eclipta 10g, chrysanthemum 5g, golden flower tea peel 25g, root of Dahurain angelica 5g, root of kudzu vine 8g.
A kind of preparation method of above-mentioned Camellia nitidissima bagged instant preparation for treating anaphylactia, comprises the following steps:
(1) each component raw material is weighed by weight ratio, and 2h is dried at 100 DEG C after rinsing, it is stand-by;
(2) crushing of juice medicinal material is inhaled:It is ground into after the Asian puccoon 5g weighed up, madder 10g, eclipta 10g, chrysanthemum 5g are mixed Fine powder, crosses 20 mesh sieves, obtains inhaling juice fine powder;
(3) extraction of decoction liquor:Coarse powder is ground into after the golden flower tea peels 25g weighed up, root of Dahurain angelica 5g, root of kudzu vine 8g are mixed, Plus 15 times of water, 10min is soaked, decocts and extracts 3 times, decocting time is 3h+2h+1h, merges decoction liquor, with the yarn of 4 layer of 15 mesh Cloth is filtered, and final decoction liquor is obtained after filtering;
(4) concentrate:The decoction liquor of gained in step (3) is concentrated by evaporation into relative to the thick paste that water relative density is 1.3;
(5) mix:Thick paste obtained by step (4) is well mixed with inhaling juice fine powder obtained by step (2), treats that thick paste is thin to inhaling juice After powder absorption completely, 65 DEG C are dried, and obtain dried powder;
(6) particle is prepared:The ethanol of addition 50% in dried powder obtained by step (5), carries out wet granulation, will be made Particle is crossed after 20 mesh sieves, dry sterilization, is sub-packed in filter paper bag, produces Camellia nitidissima bagged instant preparation;
The Camellia nitidissima bagged instant preparation of above-mentioned treatment anaphylactia is put into 2L water and soaked 20 minutes, rear slow fire is boiled in heating Fried 20min, then removes dregs of a decoction bag, treats that water temperature is down to 35 DEG C, smoked to wash affected part 20min, and daily smoke is washed 2 times.
Embodiment 3
A kind of Camellia nitidissima bagged instant preparation for treating anaphylactia, includes the raw material of following parts by weight:Asian puccoon 10g, madder 10g, eclipta 7g, chrysanthemum 8g, golden flower tea peel 20g, root of Dahurain angelica 7g, root of kudzu vine 13g.
A kind of preparation method of above-mentioned Camellia nitidissima bagged instant preparation for treating anaphylactia, comprises the following steps:
(1) each component raw material is weighed by weight ratio, and 2h is dried at 100 DEG C after rinsing, it is stand-by;
(2) crushing of juice medicinal material is inhaled:It is ground into after the Asian puccoon 10g weighed up, madder 10g, eclipta 7g, chrysanthemum 8g are mixed Fine powder, crosses 25 mesh sieves, obtains inhaling juice fine powder;
(3) extraction of decoction liquor:Coarse powder is ground into after the golden flower tea peels 20g weighed up, root of Dahurain angelica 7g, root of kudzu vine 13g are mixed, Plus 15 times of water, 15min is soaked, decocts and extracts 3 times, decocting time is 3h+2h+1h, merges decoction liquor, with the yarn of 4 layer of 15 mesh Cloth is filtered, and final decoction liquor is obtained after filtering;
(4) concentrate:By the decoction liquor of gained in step (3) be concentrated by evaporation into the relative density relative to water for 1.2 it is thick Cream;
(5) mix:Thick paste obtained by step (4) is well mixed with inhaling juice fine powder obtained by step (2), treats that thick paste is thin to inhaling juice After powder absorption completely, 65 DEG C are dried, and obtain dried powder;
(6) particle is prepared:The ethanol of addition 60% in dried powder obtained by step (5), carries out wet granulation, will be made Particle is crossed after 20 mesh sieves, dry sterilization, is sub-packed in filter paper bag, produces Camellia nitidissima bagged instant preparation;
The Camellia nitidissima bagged instant preparation of above-mentioned treatment anaphylactia is put into 2L water and soaked 30 minutes, rear slow fire is boiled in heating Fried 30min, then removes dregs of a decoction bag, treats that water temperature is down to 40 DEG C, smoked to wash affected part 20min, and daily smoke is washed 2 times.
Embodiment 4
A kind of Camellia nitidissima bagged instant preparation for treating anaphylactia, includes the raw material of following parts by weight:Asian puccoon 15g, madder 10g, eclipta 10g, chrysanthemum 8g, golden flower tea peel 30g, root of Dahurain angelica 5g, root of kudzu vine 10g.
A kind of preparation method of above-mentioned Camellia nitidissima bagged instant preparation for treating anaphylactia, comprises the following steps:
(1) each component raw material is weighed by weight ratio, and 2h is dried at 100 DEG C after rinsing, it is stand-by;
(2) crushing of juice medicinal material is inhaled:Crushed after the Asian puccoon 15g weighed up, madder 10g, eclipta 10g, chrysanthemum 8g are mixed Into fine powder, 25 mesh sieves are crossed, obtain inhaling juice fine powder;
(3) extraction of decoction liquor:Coarse powder is ground into after the golden flower tea peels 30g weighed up, root of Dahurain angelica 5g, root of kudzu vine 10g are mixed, Plus 20 times of water, 15min is soaked, decocts and extracts 3 times, decocting time is 3h+2h+1h, merges decoction liquor, with the yarn of 4 layer of 15 mesh Cloth is filtered, and final decoction liquor is obtained after filtering;
(4) concentrate:By the decoction liquor of gained in step (3) be concentrated by evaporation into the relative density relative to water for 1.4 it is thick Cream;
(5) mix:Thick paste obtained by step (4) is well mixed with inhaling juice fine powder obtained by step (2), treats that thick paste is thin to inhaling juice After powder absorption completely, 65 DEG C are dried, and obtain dried powder;
(6) particle is prepared:The ethanol of addition 60% in dried powder obtained by step (5), carries out wet granulation, will be made Particle is crossed after 15 mesh sieves, dry sterilization, is sub-packed in filter paper bag, produces Camellia nitidissima bagged instant preparation;
The Camellia nitidissima bagged instant preparation of above-mentioned treatment anaphylactia is put into 3L water and soaked 20 minutes, rear slow fire is boiled in heating Fried 40min, then removes dregs of a decoction bag, treats that water temperature is down to 40 DEG C, smoked to wash affected part 20min, and daily smoke is washed 1 time.
Conditioning for anaphylactia state improves clinical observation statistics:
1st, case is chosen:The anaphylactia patient 200 made a definite diagnosis is clinically chosen, at 20~70 years old age, male 150 Example, women 50 is divided into four groups of experimental groups 1~4, every group 50.
2nd, experimental method:Give experimental group 1~4 respectively using the embodiment of the present invention 1~4 prepare bagged instant preparation, respectively according to The embodiment of embodiment 1~4 is implemented, continuous to use one month, observes and record the recovery situation of patient.
3rd, curative effect determinate standard:Effectively:Anaphylactia clinical symptom disappearance, every sign recovers normal, in half a year not See recurrence;It is effective:Anaphylactia clinical symptoms improve, and the performance of each sign is clearly better before patient compares medication;It is invalid:Disease Feelings are without any improvement or aggravate.
4th, experimental data is counted:
Classification Case load Effectively It is effective It is invalid Adverse reaction It is efficient
Embodiment 1 50 30 19 1 0 98.0
Embodiment 2 50 24 26 0 0 100.0
Embodiment 3 50 28 20 2 0 96.0
Embodiment 4 50 28 22 0 0 100.0
5th, experimental result:As can be seen from the above experimental data, the Camellia nitidissima antiallergy bagged instant preparation for preparing of the present invention for The total effective rate of the treatment of anaphylactia is 98.5%, and 200 patients have no any adverse reaction, therefore explanation, this hair Bright Camellia nitidissima antiallergy bagged instant preparation is the safe and effective medicine for treating anaphylactia, with good clinical expansion meaning.

Claims (8)

1. a kind of Camellia nitidissima bagged instant preparation for treating anaphylactia, it is characterised in that:In parts by weight, by 40~60 parts of suction juice Medicinal material and 40~60 parts of decoction liquor medicinal material are formulated;
Wherein, the suction juice medicinal material, includes the raw material components of following parts by weight:5~15 parts of Asian puccoon, 5~15 parts of madder, eclipta 5~15 parts, 3~8 parts of chrysanthemum;
The decoction liquor medicinal material, includes the raw material components of following parts by weight:15~30 parts of golden flower tea peels, 3~8 parts of the root of Dahurain angelica, Pueraria lobota 4~14 parts of root.
2. a kind of Camellia nitidissima bagged instant preparation for treating anaphylactia as claimed in claim 1, it is characterised in that the suction juice medicine Material, in parts by weight, including 5 parts of 10 parts of Asian puccoon, 10 parts of madder, 10 parts of eclipta and chrysanthemum.
3. a kind of Camellia nitidissima bagged instant preparation for treating anaphylactia as claimed in claim 1, it is characterised in that the decoction liquor Medicinal material, in parts by weight, including 10 parts of 20 parts of golden flower tea peels, 7 parts of the root of Dahurain angelica and the root of kudzu vine.
4. a kind of preparation method for the Camellia nitidissima bagged instant preparation for treating anaphylactia as claimed in claim 1, it is characterised in that Comprise the following steps:
(1) each component raw material is weighed by proportioning, is dried after rinsing, it is stand-by;
(2) crushing of juice medicinal material is inhaled:Asian puccoon after drying, madder, eclipta, chrysanthemum will be ground into fine powder after mixing, cross 10~ 40 mesh sieves, obtain inhaling juice fine powder;
(3) extraction of decoction liquor:Coarse powder is ground into after golden flower tea peels after drying, the root of Dahurain angelica, the root of kudzu vine are mixed, plus 10~20 times Water, soak 10~20min, decoct extract 1~3 time, decocting time be 1~3h, merge decoction liquor, obtain final after filtering Decoction liquor;
(4) concentrate:By the decoction liquor of gained in step (3) be concentrated by evaporation into the relative density relative to water for 1.2~1.4 it is thick Cream;
(5) mix:Thick paste obtained by step (4) is well mixed with inhaling juice fine powder obtained by step (2), treats that thick paste is inhaled to inhaling juice fine powder It is attached completely after, be dried, obtain dried powder;
(6) particle is prepared:The ethanol of addition 50%~60% in the dried powder obtained by step (5), carries out wet granulation, will Obtained particle is crossed after 10~20 mesh sieves, dry sterilization, and quantitative separating is in filter paper bag, producing Camellia nitidissima bagged instant preparation.
5. a kind of preparation method for the Camellia nitidissima bagged instant preparation for treating anaphylactia as claimed in claim 4, it is characterised in that The temperature of drying is 100 DEG C in step (1), and drying time is 2h.
6. a kind of preparation method for the Camellia nitidissima bagged instant preparation for treating anaphylactia as claimed in claim 4, it is characterised in that Filtering in step (3) is filtered with 4 layers of gauze, and gauze used is 15 mesh gauzes.
7. a kind of preparation method for the Camellia nitidissima bagged instant preparation for treating anaphylactia as claimed in claim 4, it is characterised in that The temperature dried in step (5) is 65 DEG C.
8. the preparation method of the Camellia nitidissima bagged instant preparation of anaphylactia is treated as claimed in claim 4, it is characterised in that every bag The quality of bagged instant preparation is 65~100g.
CN201710332827.6A 2017-05-12 2017-05-12 It is a kind of to treat Camellia nitidissima bagged instant preparation of anaphylactia and preparation method thereof Pending CN107184737A (en)

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Application publication date: 20170922