CN108201549A - A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma and preparation method thereof - Google Patents

A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma and preparation method thereof Download PDF

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Publication number
CN108201549A
CN108201549A CN201810204262.8A CN201810204262A CN108201549A CN 108201549 A CN108201549 A CN 108201549A CN 201810204262 A CN201810204262 A CN 201810204262A CN 108201549 A CN108201549 A CN 108201549A
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parts
preparation
bagged instant
desmodium triquetrum
allergic asthma
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史丽颖
靳京妹
于大永
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Dalian University
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Dalian University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The present invention relates to tcm field, desmodium triquetrum bagged instant preparation of specifically a kind for the treatment of allergic asthma and preparation method thereof.The desmodium triquetrum bagged instant preparation is obtained by following Chinese medicine composition by weight:Cucurbit tealeaves 10 ~ 25, perilla leaf 5 ~ 15, ternip 5 ~ 15, windproof 5 ~ 15, cicada slough 10 ~ 20, chrysanthemum 3 ~ 8, peppermint 4 ~ 14.Raw material is is rinsed, dedusting, dried by the preparation method of the bagged instant preparation, after drying, by cucurbit tealeaves, perilla leaf, chrysanthemum, peppermint co-grinding into fine powder, it is allowed to be absorbed in fine powder after remaining medicinal material extract concoction, it is uniformly mixed, last quantitative separating is in the desmodium triquetrum bagged instant preparation that treatment allergic asthma is made in filter paper bag.The present invention has effectively played the antianaphylactic medicinal effects of cucurbit tealeaves, desmodium triquetrum antiallergy bagged instant preparation is made by the reasonable compatibility of plurality of Chinese, safe and non-toxic, and bagged instant preparation form is made, facilitates the carrying and use.

Description

A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma and preparation method thereof
Technical field
The present invention relates to tcm field, the desmodium triquetrum bagged instant preparation of specifically a kind for the treatment of allergic asthma and its preparation side Method.
Background technology
Asthma is a kind of common disease, frequently-occurring disease, and many adverse effects are caused to human health.Whole world asthmatic patient at present About 300,000,000 people, China's asthmatic patient about 30,000,000 have nearly 200,000 people to die of asthma every year.Current treating asthma is generally using sugared skin Matter hormone controls the chronic inflammation of air flue.However, hormone medicine can only mitigate symptom, the basic reason of asthma can not be directed to It is treated, and it is larger that side effect is used for a long time.The pathogenesis of allergic asthma is complicated, is a kind of thin by acidophil granules The air flue chronic allergic reaction diseases associated with inflammation that the inflammatory cells such as born of the same parents, T lymphocytes, mast cell, human airway epithelial cells participate in. Life style that modern society brings and variation environmentally so that allelgic asthma disease has increased trend year by year.This is not Only inconvenience being brought to daily life, causing mental suffering, reduction quality of life, and the duration is long, some becomes hardly possible The disease controlled, also having leads to died.
Desmodium triquetrum main product is in Guangxi, Jiangxi, Guangdong, Fujian and other places.With clearing heat and detoxicating, disperse accumulation dampness removing, desinsection anti-corrosion etc. Effect is clinically used for treatment cold, fever, abscess of throat, acute nephritis, icterepatitis, enteritis, bacillary dysentery, gestation and vomits It spits.Modern pharmacology research shows that desmodium triquetrum has a variety of pharmacological activity such as anti-inflammatory, antibacterial, anti-oxidant.Chemical research shows Cucurbit tealeaves mainly contains the ingredients such as flavones, isoflavones, cumarin, polyphenol.Experimental studies have found that desmodium triquetrum has stronger resist Allergic asthma acts on.
At present, the drug of allergic asthma is treated based on Western medicine, western medicine treatment effect is clear and definite but toxic side effect is big, and in Medical instrument has the advantage not available for Western medicine, and the Chinese medicine compound prescription that treatment allergic asthma is prepared using desmodium triquetrum as main ingredient has not been reported, The medical value of desmodium triquetrum is not not fully exerted.
Invention content
The object of the present invention is to provide a kind of desmodium triquetrum bagged instant preparations for treating allergic asthma and preparation method thereof.
For achieving the above object, the present invention uses following technical scheme:
A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma, in parts by weight, by 30 ~ 50 parts of suction juice medicinal material and 30 ~ 50 parts Decoction liquor medicinal material be formulated;Wherein, the raw material components that juice medicinal material includes following parts by weight are inhaled:10 ~ 25 parts of cucurbit tealeaves, purple 5 ~ 15 parts of perilla leaf, 3 ~ 8 parts of chrysanthemum, 4 ~ 14 parts of peppermint;Decoction liquor medicinal material includes the raw material components of following parts by weight:Ternip 5 ~ 15 Part, 5 ~ 15 parts windproof, 10 ~ 20 parts of cicada slough.
A kind of above-mentioned desmodium triquetrum bagged instant preparation for treating allergic asthma, the suction juice medicinal material, in parts by weight, including calabash 15 parts of reed tealeaves, 10 parts of perilla leaf, 6 parts of chrysanthemum, 8 parts of peppermint.
A kind of above-mentioned desmodium triquetrum bagged instant preparation for treating allergic asthma, the decoction liquor medicinal material, in parts by weight, including 12 parts of ternip, 9 parts windproof, 12 parts of cicada slough.
A kind of above-mentioned preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma, includes the following steps:
(1)Each component raw material is weighed by proportioning, is dried after rinsing, for use;
(2)Inhale the crushing of juice medicinal material:By after drying cucurbit tealeaves, perilla leaf, chrysanthemum, peppermint mix after be ground into fine powder, mistake 15 ~ 35 mesh sieve, and obtain inhaling juice fine powder;
(3)The extraction of decoction liquor:By after drying ternip, windproof, cicada slough mix after be ground into coarse powder, add 10 ~ 20 times of water, 15 ~ 20min is impregnated, decocts extraction 1 ~ 3 time, decocting time is 1 ~ 3h, merges decoction liquor, final decoction liquor is obtained after filtering;
(4)Concentration:By step(3)The decoction liquor of middle gained be concentrated by evaporation into the relative density relative to water be 1.2 ~ 1.4 it is thick Cream;
(5)Mixing:By step(4)Gained thick paste and step(2)Gained is inhaled juice fine powder and is uniformly mixed, and treats that thick paste is inhaled to inhaling juice fine powder It is attached completely after, be dried, obtain dried powder;
(6)Prepare particle:In step(5)50% ~ 60% ethyl alcohol is added in the dried powder of gained, wet granulation is carried out, will make Particle cross 10 ~ 20 mesh sieve, after dry sterilization, quantitative separating in filter paper bag to get desmodium triquetrum bagged instant preparation.
A kind of above-mentioned preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma, step(1)The temperature of middle drying It is 100 DEG C, drying time 2h.
A kind of above-mentioned preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma, step(3)In filtering be with 8 Layer gauze is filtered, and gauze used is 20 mesh gauzes.
A kind of upper preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma, step(5)The temperature of middle drying Spend is 65 DEG C.
A kind of above-mentioned preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma, the quality of every bag of bagged instant preparation is 70 ~100g。
Application method:The desmodium triquetrum bagged instant preparation for treating allergic asthma is put into 1 ~ 3L water and is impregnated 20 ~ 30 minutes, is heated Fried 25 ~ the 35min of rear slow boiling is boiled, dregs of a decoction bag is then removed, treats that water temperature is down to 35 ~ 40 DEG C, it is smoked to wash 10 ~ 20min of affected part, daily It is smoked to wash 1 ~ 2 time.
In the present invention, the effect of each Chinese medicine material medicinal material, is as follows:
Perilla leaf:Pungent, tepor, it is nontoxic.It delivers, cold dispelling, qi-regulating and battalion.Cure cold chill, fever with aversion to cold, cough, nothing of having a headache Sweat, asthma, fullness and oppression of chest and abdomen, evil of vomitting diarrhea are blocked, pernicious vomiting, fetal irritability in pharynx.
Ternip:Lower gas helps digestion, eliminating phlegm moistening lung, and removing toxic substances is promoted the production of body fluid and middle cough-relieving, sharp stool and urine.
It is windproof:Taste acrid, sweet, warm.Return wing flesh, liver, the spleen channel.Inducing diaphoresis to dispel wind is cured mainly, wins wet, relieving convulsion.With analgesia, antibacterial, The effects that antipyretic.
Cicada slough:It is sweet, it trembles with fear.Enter lung, Liver Channel.Dissipate wind-heat moves back mesh screen, breathes freely, the functions such as spasmolysis.Flu point heat, hoarse voice are cured mainly, Measles without adequate eruption, rubella are had an itch, pediatric epilepsy scared.
Chrysanthemum:Property it is sweet, be slightly cold, have effects that dissipate wind-heat, flat liver improving eyesight, the cough that disappears analgesic.
Peppermint:Acrid flavour, it is cool in nature;Return lung, Liver Channel;Faint scent, which rises, to be dissipated;With wind-dispelling heat-dissipating, refresh oneself, throat, promoting eruption, solution The effect of strongly fragrant;Cure mainly wind-heat table disease, dizziness of having a headache, red eye, swell pain, sore throat sound dumb, nasosinusitis, toothache, measles without adequate eruption, urticaria itch, Liver-depressed hypochondrium pain gastral cavity is swollen, scrofula tuberculosis.
The traditional Chinese medical science thinks that allergy, which is searched to the bottom, is " because of empty sensitization ", the not empty then allergy self-healing of lung spleen kidney, so treatment anaphylaxis Asthma should be based on beneficial lung strengthening spleen, tonifying kidney.After the raw materials used in the present invention pharmaceutical composition, drug effect has synergistic effect, plays out facilitaing lung Gas, eliminating the phlegm apocenosis, the effect of warming spleen and stomach for dispelling cold, strengthening spleen, tonifying kidney while clinical symptoms are eliminated, correct the anaphylaxis of asthma patient Constitution reaches treating both manifestation and root cause of disease, and without obvious toxic-side effects.
Compared with prior art, beneficial effects of the present invention are:The present invention passes through plurality of Chinese using desmodium triquetrum as main ingredient Reasonable compatibility has effectively played the antianaphylactic medicinal effects of desmodium triquetrum, and desmodium triquetrum antiallergy bagged instant preparation is made, and treats anaphylaxis It asthma and has no toxic side effect.Bagged instant preparation form is made in the present invention, simple for process, applied widely, and Chinese medicine, which is decocted, to be carried fully, the dregs of a decoction point From conveniently, facilitate the carrying and use.
Specific embodiment
Below in conjunction with specific embodiment, the present invention will be further described.
Embodiment 1
A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma includes the raw material of following parts by weight:10 parts of cucurbit tealeaves, perilla leaf 5 parts, 3 parts of chrysanthemum, 4 parts of peppermint, 5 parts of ternip, 5 parts windproof, 10 parts of cicada slough.
A kind of above-mentioned preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma, includes the following steps:
(1)Each component raw material is weighed by weight ratio, dries 2h at 100 DEG C after rinsing, for use;
(2)Inhale the crushing of juice medicinal material:By powder after 4 parts of 3 parts of 5 parts of 10 parts of cucurbit tealeaves, perilla leaf, chrysanthemum weighing up, peppermint mixing Fine powder is broken into, crosses 25 mesh sieve, obtains inhaling juice fine powder;
(3)The extraction of decoction liquor:Coarse powder will be ground into after 5 parts of the ternip weighed up, 5 parts windproof, 10 parts of mixing of cicada slough, adds 15 times Water, impregnate 18min, decoct extraction 3 times, decocting time 3h+2h+1h, merge decoction liquor, carried out with the gauze of 8 layer of 20 mesh Filtering, obtains final decoction liquor after filtering;
(4)Concentration:By step(3)The decoction liquor of middle gained is concentrated by evaporation into the thick paste that the relative density relative to water is 1.3;
(5)Mixing:By step(4)Gained thick paste and step(2)Gained is inhaled juice fine powder and is uniformly mixed, and treats that thick paste is inhaled to inhaling juice fine powder It is attached completely after, 65 DEG C are dried, and obtain dried powder,;
(6)Prepare particle:In step(5)55% ethyl alcohol is added in gained dried powder, wet granulation is carried out, by obtained particle 15 mesh sieve is crossed, after dry sterilization, is sub-packed in filter paper bag to get 80g/ bags of desmodium triquetrum bagged instant preparation.
In use, one bag of bagged instant preparation is taken, which to be put into 2L water, impregnates 30min, the fried 30min of rear slow boiling is boiled in heating, then goes Except dregs of a decoction bag, treat that water temperature is down to 35 DEG C, smoked to wash affected part 15min, daily smoke is washed 2 times.
Embodiment 2
A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma includes the raw material of following parts by weight:15 parts of cucurbit tealeaves, perilla leaf 8 parts, 5 parts of chrysanthemum, 8 parts of peppermint, 9 parts of ternip, 9 parts windproof, 12 parts of cicada slough.
A kind of above-mentioned preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma, includes the following steps:
(1)Each component raw material is weighed by weight ratio, dries 2h at 100 DEG C after rinsing, for use;
(2)Inhale the crushing of juice medicinal material:By powder after 8 parts of 5 parts of 8 parts of 15 parts of cucurbit tealeaves, perilla leaf, chrysanthemum weighing up, peppermint mixing Fine powder is broken into, crosses 25 mesh sieve, obtains inhaling juice fine powder;
(3)The extraction of decoction liquor:Coarse powder will be ground into after 9 parts of the ternip weighed up, 9 parts windproof, 12 parts of mixing of cicada slough, adds 15 times Water, impregnate 18min, decoct extraction 3 times, decocting time 3h+2h+1h, merge decoction liquor, carried out with the gauze of 8 layer of 20 mesh Filtering, obtains final decoction liquor after filtering;
(4)Concentration:By step(3)The decoction liquor of middle gained is concentrated by evaporation into the thick paste that the relative density relative to water is 1.3;
(5)Mixing:By step(4)Gained thick paste and step(2)Gained is inhaled juice fine powder and is uniformly mixed, and treats that thick paste is inhaled to inhaling juice fine powder It is attached completely after, 65 DEG C are dried, and obtain dried powder;
(6)Prepare particle:In step(5)55% ethyl alcohol is added in gained dried powder, wet granulation is carried out, by obtained particle 15 mesh sieve is crossed, after dry sterilization, is sub-packed in filter paper bag to get 80g/ bags of desmodium triquetrum bagged instant preparation.
In use, one bag of bagged instant preparation is taken, which to be put into 2L water, impregnates 30min, the fried 30min of rear slow boiling is boiled in heating, then goes Except dregs of a decoction bag, treat that water temperature is down to 35 DEG C, smoked to wash affected part 15min, daily smoke is washed 2 times.
Embodiment 3
A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma includes the raw material of following parts by weight:20 parts of cucurbit tealeaves, perilla leaf 12 parts, 6 parts of chrysanthemum, 12 parts of peppermint, 12 parts of ternip, 12 parts windproof, 16 parts of cicada slough.
A kind of above-mentioned preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma, includes the following steps:
(1)Each component raw material is weighed by weight ratio, dries 2h at 100 DEG C after rinsing, for use;
(2)Inhale the crushing of juice medicinal material:After 12 parts of 6 parts of 12 parts of 20 parts of cucurbit tealeaves, perilla leaf, chrysanthemum weighing up, peppermint mixing Fine powder is ground into, crosses 25 mesh sieve, obtains inhaling juice fine powder;
(3)The extraction of decoction liquor:Coarse powder will be ground into after 12 parts of the ternip weighed up, 12 parts windproof, 16 parts of mixing of cicada slough, adds 15 Times water, impregnate 18min, decoct extraction 3 times, decocting time 3h+2h+1h, merge decoction liquor, with the gauze of 8 layer of 20 mesh into Row filtering, obtains final decoction liquor after filtering;
(4)Concentration:By step(3)The decoction liquor of middle gained is concentrated by evaporation into the thick paste that the relative density relative to water is 1.3;
(5)Mixing:By step(4)Gained thick paste and step(2)Gained is inhaled juice fine powder and is uniformly mixed, and treats that thick paste is inhaled to inhaling juice fine powder It is attached completely after, 65 DEG C are dried, and obtain dried powder,;
(6)Prepare particle:In step(5)55% ethyl alcohol is added in gained dried powder, wet granulation is carried out, by obtained particle 15 mesh sieve is crossed, after dry sterilization, is sub-packed in filter paper bag to get 80g/ bags of desmodium triquetrum bagged instant preparation.
In use, one bag of bagged instant preparation is taken, which to be put into 2L water, impregnates 30min, the fried 30min of rear slow boiling is boiled in heating, then goes Except dregs of a decoction bag, treat that water temperature is down to 35 DEG C, smoked to wash affected part 15min, daily smoke is washed 2 times.
Embodiment 4
A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma includes the raw material of following parts by weight:25 parts of cucurbit tealeaves, perilla leaf 15 parts, 8 parts of chrysanthemum, 14 parts of peppermint, 15 parts of ternip, 15 parts windproof, 20 parts of cicada slough.
A kind of above-mentioned preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma, includes the following steps:
(1)Each component raw material is weighed by weight ratio, dries 2h at 100 DEG C after rinsing, for use;
(2)Inhale the crushing of juice medicinal material:After 14 parts of 8 parts of 15 parts of 25 parts of cucurbit tealeaves, perilla leaf, chrysanthemum weighing up, peppermint mixing Fine powder is ground into, crosses 25 mesh sieve, obtains inhaling juice fine powder;
(3)The extraction of decoction liquor:Coarse powder will be ground into after 15 parts of the ternip weighed up, 15 parts windproof, 20 parts of mixing of cicada slough, adds 15 Times water, impregnate 18min, decoct extraction 3 times, decocting time 3h+2h+1h, merge decoction liquor, with the gauze of 8 layer of 20 mesh into Row filtering, obtains final decoction liquor after filtering;
(4)Concentration:By step(3)The decoction liquor of middle gained is concentrated by evaporation into the thick paste that the relative density relative to water is 1.3;
(5)Mixing:By step(4)Gained thick paste and step(2)Gained is inhaled juice fine powder and is uniformly mixed, and treats that thick paste is inhaled to inhaling juice fine powder It is attached completely after, 65 DEG C are dried, and obtain dried powder,;
(6)Prepare particle:In step(5)55% ethyl alcohol is added in gained dried powder, wet granulation is carried out, by obtained particle 15 mesh sieve is crossed, after dry sterilization, is sub-packed in filter paper bag to get 80g/ bags of desmodium triquetrum bagged instant preparation.
In use, one bag of bagged instant preparation is taken, which to be put into 2L water, impregnates 30min, the fried 30min of rear slow boiling is boiled in heating, then goes Except dregs of a decoction bag, treat that water temperature is down to 35 DEG C, smoked to wash affected part 15min, daily smoke is washed 2 times.
Embodiment 5
A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma includes the raw material of following parts by weight:15 parts of cucurbit tealeaves, perilla leaf 10 parts, 6 parts of chrysanthemum, 8 parts of peppermint, 12 parts of ternip, 9 parts windproof, 12 parts of cicada slough.
A kind of above-mentioned preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma, includes the following steps:
(1)Each component raw material is weighed by weight ratio, dries 2h at 100 DEG C after rinsing, for use;
(2)Inhale the crushing of juice medicinal material:By powder after 8 parts of 6 parts of 10 parts of 15 parts of cucurbit tealeaves, perilla leaf, chrysanthemum weighing up, peppermint mixing Fine powder is broken into, crosses 25 mesh sieve, obtains inhaling juice fine powder;
(3)The extraction of decoction liquor:Coarse powder will be ground into after 12 parts of the ternip weighed up, 9 parts windproof, 12 parts of mixing of cicada slough, adds 15 times Water, impregnate 18min, decoct extraction 3 times, decocting time 3h+2h+1h, merge decoction liquor, carried out with the gauze of 8 layer of 20 mesh Filtering, obtains final decoction liquor after filtering;
(4)Concentration:By step(3)The decoction liquor of middle gained is concentrated by evaporation into the thick paste that the relative density relative to water is 1.3;
(5)Mixing:By step(4)Gained thick paste and step(2)Gained is inhaled juice fine powder and is uniformly mixed, and treats that thick paste is inhaled to inhaling juice fine powder It is attached completely after, 65 DEG C are dried, and obtain dried powder,;
(6)Prepare particle:In step(5)55% ethyl alcohol is added in gained dried powder, wet granulation is carried out, by obtained particle 15 mesh sieve is crossed, after dry sterilization, is sub-packed in filter paper bag to get 80g/ bags of desmodium triquetrum bagged instant preparation.
In use, one bag of bagged instant preparation is taken, which to be put into 2L water, impregnates 30min, the fried 30min of rear slow boiling is boiled in heating, then goes Except dregs of a decoction bag, treat that water temperature is down to 35 DEG C, smoked to wash affected part 15min, daily smoke is washed 2 times.
Clinical observation statistics is improved for the conditioning of allergic asthma state:
1. case is chosen:The isolated from allergic asthmatic patients 60 made a definite diagnosis clinically is chosen, at 20 ~ 70 years old age, male 20, women 40 Example.
2. experimental method:60 patients use the desmodium triquetrum bagged instant preparation of embodiment 5, are used continuously one month, observe and remember Record the recovery situation of patient.
3. curative effect determinate standard:
It is effective:Allergic asthma clinical symptoms disappear, and every sign restores normal, no relapse in half a year;
Effectively:Allergic asthma clinical symptoms improve, before patient compares medication the performance of each sign be clearly better;
In vain:The state of an illness is without any improvement or aggravates.
4. clinical data:After one month, in 60 patients, effective 20, effective 35, invalid 5, adverse reaction 0, total effective rate is:91.7%.
5. result:As can be seen from the above data, the desmodium triquetrum antiallergy bagged instant preparation of the present invention is for allergic asthma The total effective rate for the treatment of is 91.7%, and 60 patients have no any adverse reaction, therefore the desmodium triquetrum antiallergy bag bubble of the present invention Agent is to treat the safe and effective drug of allergic asthma, has good clinical expansion meaning.

Claims (8)

1. a kind of desmodium triquetrum bagged instant preparation for treating allergic asthma, which is characterized in that in parts by weight, by 30 ~ 50 parts of suction juice Medicinal material and 30 ~ 50 parts of decoction liquor medicinal material are formulated;
Wherein, the suction juice medicinal material includes the raw material components of following parts by weight:10 ~ 25 parts of cucurbit tealeaves, 5 ~ 15 parts of perilla leaf, 3 ~ 8 parts of chrysanthemum, 4 ~ 14 parts of peppermint;
The decoction liquor medicinal material includes the raw material components of following parts by weight:5 ~ 15 parts of ternip, 5 ~ 15 parts windproof, cicada slough 10 ~ 20 Part.
A kind of 2. desmodium triquetrum bagged instant preparation for treating allergic asthma as described in claim 1, which is characterized in that the suction juice medicine Material includes the raw material components of following parts by weight:8 parts of 15 parts of cucurbit tealeaves, 10 parts of perilla leaf, 6 parts of chrysanthemum and peppermint.
A kind of 3. desmodium triquetrum bagged instant preparation for treating allergic asthma as described in claim 1, which is characterized in that the decoction liquor Medicinal material includes the raw material components of following parts by weight:12 parts of ternip, windproof 9 parts and 12 parts of cicada slough.
A kind of 4. preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma described in claim 1, which is characterized in that packet Include following steps:
(1)Each component raw material is weighed by proportioning, is dried after rinsing, for use;
(2)Inhale the crushing of juice medicinal material:By after drying cucurbit tealeaves, perilla leaf, chrysanthemum, peppermint mix after be ground into fine powder, mistake 15 ~ 35 mesh sieve, and obtain inhaling juice fine powder;
(3)The extraction of decoction liquor:By after drying ternip, windproof, cicada slough mix after be ground into coarse powder, add 10 ~ 20 times of water, 15 ~ 20min is impregnated, decocts extraction 1 ~ 3 time, decocting time is 1 ~ 3h, merges decoction liquor, final decoction liquor is obtained after filtering;
(4)Concentration:By step(3)The decoction liquor of middle gained be concentrated by evaporation into the relative density relative to water be 1.2 ~ 1.4 it is thick Cream;
(5)Mixing:By step(4)Gained thick paste and step(2)Gained is inhaled juice fine powder and is uniformly mixed, and treats that thick paste is inhaled to inhaling juice fine powder It is attached completely after, be dried, obtain dried powder;
(6)Prepare particle:In step(5)50% ~ 60% ethyl alcohol is added in the dried powder of gained, wet granulation is carried out, will make Particle cross 10 ~ 20 mesh sieve, after dry sterilization, quantitative separating in filter paper bag to get desmodium triquetrum bagged instant preparation.
5. a kind of preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma as claimed in claim 4, which is characterized in that Step(1)The temperature of middle drying is 100 DEG C, drying time 2h.
6. a kind of preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma as claimed in claim 4, which is characterized in that Step(3)Middle filtering is filtered with 8 layers of gauze, and gauze used is 20 mesh gauzes.
7. a kind of preparation method of desmodium triquetrum bagged instant preparation for treating allergic asthma as claimed in claim 4, which is characterized in that Step(5)The temperature of middle drying is 65 DEG C.
8. the preparation method of the desmodium triquetrum bagged instant preparation for the treatment of allergic asthma as claimed in claim 4, which is characterized in that every bag The quality of bagged instant preparation is 70 ~ 100g.
CN201810204262.8A 2018-03-13 2018-03-13 A kind of desmodium triquetrum bagged instant preparation for treating allergic asthma and preparation method thereof Pending CN108201549A (en)

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Application publication date: 20180626