CN107519473A - One kind moistens the lung and relieve the cough composition and preparation method thereof - Google Patents
One kind moistens the lung and relieve the cough composition and preparation method thereof Download PDFInfo
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- CN107519473A CN107519473A CN201710951962.9A CN201710951962A CN107519473A CN 107519473 A CN107519473 A CN 107519473A CN 201710951962 A CN201710951962 A CN 201710951962A CN 107519473 A CN107519473 A CN 107519473A
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Abstract
Moistened the lung and relieve the cough composition the invention discloses one kind, the composition that moistens the lung and relieve the cough is prepared by the traditional Chinese medicinal components of following parts by weight:8 20 parts of dried orange peel, 3 10 parts of ginger, 8 20 parts of the bighead atractylodes rhizome, 10 20 parts of Radix Codonopsis, 10 40 parts of cordate houttuynia, 2 15 parts of perilla leaf, 8 25 parts of cassia twig, 10 30 parts of radix pseudostellariae, 5 20 parts of honeysuckle, 5 15 parts of schizonepeta, 5 15 parts of bulb of thunberg fritillary.The preparation medication that moistens the lung and relieve the cough of the present invention is few, evident in efficacy, has no side effect, its preparation method is simple;Good drug efficacy, it can alleviate in the short period of time and cure patient cough symptom, there are the good effects to moisten the lung and relieve the cough;Traditional Chinese medicine ingredients, therapeutic process have no side effect, non-stimulated, uneasy to recur;Various auxiliary materials can be added, various formulations are made, so as to meet the needs of different crowd.
Description
Technical field
The present invention relates to the bechic technical field of Chinese medicine, and in particular to one kind moistens the lung and relieve the cough composition and its preparation side
Method.
Background technology
Cough is a kind of common breathing problem, and it is by trachea-bronchial epithelial cell mucous membrane or pleura by inflammation, foreign matter, physics
Or chemical irritation causes.Tracheopathy can be diffused into bronchus by cough, and violent cough can cause hemorrhage from respiratory tract, shadow
Rest is rung, and causes the broken ring of alveolar wall elastic fibrous tissue, so as to induce various tuberculosis.
At present, the medicine of common treatment cough is Western medicine, and Western medicine is a kind of chemicals, has certain side effect,
And the shortcomings of easily recurring, abuse of antibiotics clinically also be present, this has certain infringement to human body.Also have in some
The medicine of medicine cough-relieving, but due to reasons such as prescriptions, dosage is larger, but offer limited effectiveness.
Therefore, it is necessary to research and develop a kind of medication it is few, it is evident in efficacy, have no side effect and the non-stimulated composition that moistens the lung and relieve the cough.
The content of the invention
It is an object of the invention to provide a kind of medication it is few, it is evident in efficacy, have no side effect and the non-stimulated group that moistens the lung and relieve the cough
Compound, the preparation method of composition that moistens the lung and relieve the cough is simple, and various formulations can be made as needed, so as to meet different crowd not
Same demand.The technical solution adopted by the present invention is:One kind moistens the lung and relieve the cough composition, and the composition that moistens the lung and relieve the cough is by following weight
The traditional Chinese medicinal components of number are prepared:Dried orange peel 8-20 parts, ginger 3-10 parts, bighead atractylodes rhizome 8-20 parts, Radix Codonopsis 10-20 parts, cordate houttuynia 10-
40 parts, perilla leaf 2-15 parts, cassia twig 8-25 parts, radix pseudostellariae 10-30 parts, honeysuckle 5-20 parts, schizonepeta 5-15 parts, bulb of thunberg fritillary 5-15
Part.
Preferably, the composition that moistens the lung and relieve the cough is prepared by the traditional Chinese medicinal components of following parts by weight:Dried orange peel 12-18
Part, ginger 5-8 parts, bighead atractylodes rhizome 10-18 parts, Radix Codonopsis 12-16 parts, cordate houttuynia 18-32 parts, perilla leaf 5-12 parts, cassia twig 10-25 parts,
Radix pseudostellariae 12-20 parts, honeysuckle 10-18 parts, schizonepeta 8-12 parts, bulb of thunberg fritillary 8-12 parts.
Preferably, the composition that moistens the lung and relieve the cough is prepared by the traditional Chinese medicinal components of following parts by weight:12 parts of dried orange peel, it is raw
6 parts of ginger, 10 parts of the bighead atractylodes rhizome, 15 parts of Radix Codonopsis, 20 parts of cordate houttuynia, 5 parts of perilla leaf, 15 parts of cassia twig, 15 parts of radix pseudostellariae, 12 parts of honeysuckle,
10 parts of schizonepeta, 8 parts of bulb of thunberg fritillary.
Preferably, the composition that moistens the lung and relieve the cough is prepared by the traditional Chinese medicinal components of following parts by weight:15 parts of dried orange peel, it is raw
8 parts of ginger, 15 parts of the bighead atractylodes rhizome, 16 parts of Radix Codonopsis, 28 parts of cordate houttuynia, 10 parts of perilla leaf, 20 parts of cassia twig, 18 parts of radix pseudostellariae, 15 parts of honeysuckle,
8 parts of schizonepeta, 10 parts of bulb of thunberg fritillary.
It is dried orange peel bitter, pungent, it is warm-natured, there is the effect of regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm, can be used for treating abdominal fullness and distention, food
The illnesss such as few vomiting and diarrhoea, coughing with a lot of sputum.
There is ginger Energy benefit taste, kind middle benefit gas stopping nausea and vomiting by lowering the adverse flow of QI, dehumidifying to disappear ruffian, cough-relieving apophlegmatic, Energy benefit taste, the effect of dispersing wind and cold,
Cure mainly cold headache, nasal obstruction, cough with dyspnea, etc. illness.
The bighead atractylodes rhizome is sweet, slight bitter, has bowl spares eliminating dampness, slakes thirst and help produce saliva, beneficial spleen essence, nourishing the stomach gas and other effects.
Radix Codonopsis is sweet, flat, has tonifying middle-Jiao and Qi, clearing heat and detoxicating, expelling phlegm and arresting coughing and other effects, available for treatment spleen eating less just
The illnesss such as half congealed, weakness of limbs, palpitaition, shortness of breath, dry, spontaneous perspiration, prolapse of the anus and the prolapse of uterus.
Cordate houttuynia acrid flavour, it is cold, return lung warp, there is clearing heat and detoxicating, detumescence to treat sore, promoting urination and removing dampness, clearing away heat to cure dysentery, stomach invigorating
Help digestion and other effects, can be used for treating real heat, heat toxin, damp evil, disease heat is lung carbuncle, sore swollen toxin, hemorrhoidal hemorrhage, the taste product suffered from
The illnesss such as heat, also with the effect such as antibacterial, antiviral, raising immunity of organisms, diuresis.
Perilla leaf acrid flavour, tepor, it can be used for treating cold, fever with aversion to cold, cough, asthma, fullness and oppression of chest and abdomen.
Cassia twig nature and flavor acrid, sweet, warm, can cold-dispelling, cold, fever with chilliness can be treated, have complement sun, promoting blood circulation,
The effect of warming spleen and stomach, sweating expelling pathogenic factors from muscles and skin, warming meridians and promoting circulation of qi, helps yang transforming qi, eliminating cold to stop pain, available for treatment anemofrigid cold, coldness and pain in the epigastrium,
Blood trembles with fear Amenorrhea, joint pain, phlegm and retained fluid, oedema and palpitaition etc..
Radix pseudostellariae is sweet, slight bitter, mild-natured, has and replenishes qi to invigorate the spleen, be promoting production of body fluid and nourishing the lung and other effects, available for treat insufficiency of the spleen body it is tired,
Poor appetite, eak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration are thirsty, dryness of the lung dry cough etc..
Honeysuckle property sweet cold air fragrance, clear heat with drugs of sweet flavour and cold nature without injuring one's stomach, fragrance thoroughly up to again can eliminating evil, can dispelling wind-heat, also
Can be with removing summer-heat blood poison, for various febrile diseases, such as body heat, dermexanthesis, hair spot, heat toxin sore carbuncle, abscess of throat disease, significant effect.
Schizonepeta taste is put down, warm-natured, nontoxic, and faint scent is dense, energy town phlegm, wind-dispelling, cool blood, can effectively treat influenza, headache
Fever and chills sweating, there is improving eyesight, solution lung, liver, throat heat pain, detumescence and other effects.
It is bulb of thunberg fritillary bitter, cold in nature, there is clearing heat and eliminating phlegm, open the effect of strongly fragrant dissipating bind, antibechic, spasmolysis, can be used for treating wind-heat,
The illnesss such as scorching, phlegm-heat cough, scrofula, goiter and tumor, sore and toxic, lung carbuncle.
Present invention also offers the preparation method for the composition that moistens the lung and relieve the cough, comprise the following steps:
1) various traditional Chinese medicinal components are respectively crushed into various corresponding medicinal powder;
2) medicinal powder of step 1) is stirred, adds the 6-10 times of ethanol measured, soaked 8-12 days, heating extraction, obtain
Mixed liquor containing effective component of chinese medicine;
3) mixed liquor is centrifuged, filtered, removed the dregs of a decoction, obtain filtrate;
4) filtrate is concentrated in vacuo, obtains concentrate;
5) concentrate is dried in vacuo, obtains the composition that moistens the lung and relieve the cough.
Preferably, the particle diameter of the medicinal powder in step 1) is 20-80 mesh.
Crushing typically use medicinal herb grinder, for humidity it is higher or have viscosity traditional Chinese medicine ingredients, can be by Chinese medicine
It is put into pot, small fire heating, and stirs, so that Chinese medicine homogeneous heating, until pharmaceutical drying, is then crushed again.
Preferably, in step 2), heating extraction concrete operations are:Heating extraction 2-3 times, each 1-2h, obtain extract solution and
The dregs of a decoction, merge extract solution;Add 10-12 times of decocting to boil twice the dregs of a decoction again, each 1.5-3h, filtering, merge decoction liquor, will merge
Extract solution afterwards is well mixed with the decoction liquor merged, obtains mixed liquor.
Preferably, in step 3), the condition control of centrifugation is:Centrifugation time 8-15min, centrifuge speed 3000-
6000r/min;In step 4), the vacuum degree control of vacuum concentration is -0.02~-0.08MPa, and the density of concentrate is 1.2-
1.6Kg/m3;In step 5), vacuum drying vacuum degree control is -0.03~-0.1MPa, and temperature is 50-80 DEG C, drying time
For 10-18h.
Moistened the lung and relieve the cough preparation present invention also offers one kind, the preparation that moistens the lung and relieve the cough includes moisten the lung and relieve the cough composition and medicine
Acceptable carrier on.
Preferably, the preparation that moistens the lung and relieve the cough is pill, powder, tablet, granule or capsule.
The beneficial effects of the invention are as follows:The preparation medication that moistens the lung and relieve the cough of the present invention is few, evident in efficacy, has no side effect, and it is made
Preparation Method is simple;Good drug efficacy, it can alleviate in the short period of time and cure patient cough symptom, have what is moistened the lung and relieve the cough
Good effects;Traditional Chinese medicine ingredients, therapeutic process have no side effect, non-stimulated, uneasy to recur;Various auxiliary materials can be added, are made various
Formulation, so as to meet the needs of different crowd.
Embodiment
Embodiment 1
One kind moistens the lung and relieve the cough composition, is prepared by the traditional Chinese medicinal components of following parts by weight:8 parts of dried orange peel, 3 parts of ginger,
8 parts of the bighead atractylodes rhizome, 10 parts of Radix Codonopsis, 10 parts of cordate houttuynia, 2 parts of perilla leaf, 8 parts of cassia twig, 10 parts of radix pseudostellariae, 5 parts of honeysuckle, 5 parts of schizonepeta, Zhejiang
5 parts of shellfish.
Moisten the lung and relieve the cough the preparation method of composition, comprises the following steps:
1) various traditional Chinese medicinal components are respectively crushed into the medicinal powder that various corresponding particle diameters are 20 mesh;
2) medicinal powder of step 1) is stirred, adds the ethanol of 6 times of amounts, soaked 8 days, heating extraction 2 times, each 1h,
Extract solution and the dregs of a decoction are obtained, merge extract solution;Add 10 times of decoctings to boil twice the dregs of a decoction again, each 1.5h, filtering, merge decoction liquor,
Extract solution after merging is well mixed with the decoction liquor merged, obtains mixed liquor;
3) by mixed liquor, under rotating speed 3000r/min, 15min is centrifuged, filtering, the dregs of a decoction is removed, obtains filtrate;
4) filtrate is concentrated in vacuo in the case where vacuum is -0.02MPa, it is 1.2Kg/m to obtain density3Concentrate;
5) it is -0.03MPa in vacuum by concentrate, temperature is at 80 DEG C, carries out vacuum drying 10h, obtains moistening lung and stop
Cough composition.
Embodiment 2
One kind moistens the lung and relieve the cough composition, is prepared by the traditional Chinese medicinal components of following parts by weight:12 parts of dried orange peel, 5 parts of ginger,
10 parts of the bighead atractylodes rhizome, 12 parts of Radix Codonopsis, 18 parts of cordate houttuynia, 5 parts of perilla leaf, 10 parts of cassia twig, 12 parts of radix pseudostellariae, 10 parts of honeysuckle, schizonepeta 8
Part, 8 parts of bulb of thunberg fritillary.
Moisten the lung and relieve the cough the preparation method of composition, comprises the following steps:
1) various traditional Chinese medicinal components are respectively crushed into the medicinal powder that various corresponding particle diameters are 50 mesh;
2) medicinal powder of step 1) is stirred, adds the ethanol of 8 times of amounts, soaked 10 days, heating extraction 3 times, every time
1.5h, extract solution and the dregs of a decoction are obtained, merge extract solution;Add 12 times of decoctings to boil twice the dregs of a decoction again, each 2h, filtering, merge and decoct
Liquid, the extract solution after merging is well mixed with the decoction liquor merged, obtains mixed liquor;
3) by mixed liquor, under rotating speed 5000r/min, 12min is centrifuged, filtering, the dregs of a decoction is removed, obtains filtrate;
4) filtrate is concentrated in vacuo in the case where vacuum is -0.06MPa, it is 1.2-1.6Kg/m to obtain density3Concentration
Liquid;
5) it is -0.06MPa in vacuum by concentrate, temperature is at 60 DEG C, carries out vacuum drying 16h, obtains moistening lung and stop
Cough composition.
Embodiment 3
One kind moistens the lung and relieve the cough composition, is prepared by the traditional Chinese medicinal components of following parts by weight:12 parts of dried orange peel, 6 parts of ginger,
10 parts of the bighead atractylodes rhizome, 15 parts of Radix Codonopsis, 20 parts of cordate houttuynia, 5 parts of perilla leaf, 15 parts of cassia twig, 15 parts of radix pseudostellariae, 12 parts of honeysuckle, schizonepeta 10
Part, 8 parts of bulb of thunberg fritillary.
Moisten the lung and relieve the cough the preparation method of composition, comprises the following steps:
1) various traditional Chinese medicinal components are respectively crushed into the medicinal powder that various corresponding particle diameters are 80 mesh;
2) medicinal powder of step 1) is stirred, adds the ethanol of 10 times of amounts, soaked 8 days, heating extraction 2 times, each 2h,
Extract solution and the dregs of a decoction are obtained, merge extract solution;Add 12 times of decoctings to boil twice the dregs of a decoction again, each 1.5h, filtering, merge decoction liquor,
Extract solution after merging is well mixed with the decoction liquor merged, obtains mixed liquor;
3) by mixed liquor, under rotating speed 6000r/min, 8min is centrifuged, filtering, the dregs of a decoction is removed, obtains filtrate;
4) filtrate is concentrated in vacuo in the case where vacuum is -0.08MPa, it is 1.6Kg/m to obtain density3Concentrate;
5) it is -0.1MPa in vacuum by concentrate, temperature is at 80 DEG C, carries out vacuum drying 10h, is moistened the lung and relieve the cough
Composition.
Embodiment 4
One kind moistens the lung and relieve the cough composition, is prepared by the traditional Chinese medicinal components of following parts by weight:15 parts of dried orange peel, 8 parts of ginger,
15 parts of the bighead atractylodes rhizome, 16 parts of Radix Codonopsis, 28 parts of cordate houttuynia, 10 parts of perilla leaf, 20 parts of cassia twig, 18 parts of radix pseudostellariae, 15 parts of honeysuckle, schizonepeta 8
Part, 10 parts of bulb of thunberg fritillary.
The preparation method of composition that moistens the lung and relieve the cough and the preparation method of the composition that moistens the lung and relieve the cough of embodiment 2 are identical.
Embodiment 5
One kind moistens the lung and relieve the cough composition, is prepared by the traditional Chinese medicinal components of following parts by weight:18 parts of dried orange peel, 8 parts of ginger,
18 parts of the bighead atractylodes rhizome, 16 parts of Radix Codonopsis, 32 parts of cordate houttuynia, 12 parts of perilla leaf, 25 parts of cassia twig, 20 parts of radix pseudostellariae, 18 parts of honeysuckle, schizonepeta 12
Part, 12 parts of bulb of thunberg fritillary.
The preparation method of composition that moistens the lung and relieve the cough and the preparation method of the composition that moistens the lung and relieve the cough of embodiment 2 are identical.
Embodiment 6
One kind moistens the lung and relieve the cough composition, is prepared by the traditional Chinese medicinal components of following parts by weight:20 parts of dried orange peel, ginger 10
Part, 20 parts of the bighead atractylodes rhizome, 20 parts of Radix Codonopsis, 40 parts of cordate houttuynia, 15 parts of perilla leaf, 25 parts of cassia twig, 30 parts of radix pseudostellariae, 20 parts of honeysuckle, chaste tree
15 parts of mustard, 15 parts of bulb of thunberg fritillary.
The preparation method of composition that moistens the lung and relieve the cough and the preparation method of the composition that moistens the lung and relieve the cough of embodiment 2 are identical.
Embodiment 7
Using the composition treatment patient of moistening the lung and relieve the cough of the present invention, case quantity 200 (2000 people), application method are collected
To be oral, a 1-2g, children are cut down according to the circumstance.Oral medication 20 days, gained efficacy result Data Collection is as shown in table 1 below.
The efficacy result data of table 1
Case | Cure | It is effective | Effectively | It is invalid | It is efficient | Cure rate |
200 | 148 | 24 | 10 | 18 | 91% | 74% |
Claims (10)
- The composition 1. one kind moistens the lung and relieve the cough, it is characterised in that the Chinese medicine group of the composition by following parts by weight that moisten the lung and relieve the cough Divide and be prepared:Dried orange peel 8-20 parts, ginger 3-10 parts, bighead atractylodes rhizome 8-20 parts, Radix Codonopsis 10-20 parts, cordate houttuynia 10-40 parts, perilla leaf 2-15 parts, cassia twig 8-25 parts, radix pseudostellariae 10-30 parts, honeysuckle 5-20 parts, schizonepeta 5-15 parts, bulb of thunberg fritillary 5-15 parts.
- 2. the composition according to claim 1 that moistens the lung and relieve the cough, it is characterised in that the composition that moistens the lung and relieve the cough is by following heavy The traditional Chinese medicinal components of amount number are prepared:Dried orange peel 12-18 parts, ginger 5-8 parts, bighead atractylodes rhizome 10-18 parts, Radix Codonopsis 12-16 parts, cordate houttuynia 18-32 parts, perilla leaf 5-12 parts, cassia twig 10-25 parts, radix pseudostellariae 12-20 parts, honeysuckle 10-18 parts, schizonepeta 8-12 parts, bulb of thunberg fritillary 8-12 parts.
- 3. the composition according to claim 2 that moistens the lung and relieve the cough, it is characterised in that the composition that moistens the lung and relieve the cough is by following heavy The traditional Chinese medicinal components of amount number are prepared:12 parts of dried orange peel, 6 parts of ginger, 10 parts of the bighead atractylodes rhizome, 15 parts of Radix Codonopsis, 20 parts of cordate houttuynia, perilla leaf 5 parts, 15 parts of cassia twig, 15 parts of radix pseudostellariae, 12 parts of honeysuckle, 10 parts of schizonepeta, 8 parts of bulb of thunberg fritillary.
- 4. the composition according to claim 2 that moistens the lung and relieve the cough, it is characterised in that the composition that moistens the lung and relieve the cough is by following heavy The traditional Chinese medicinal components of amount number are prepared:15 parts of dried orange peel, 8 parts of ginger, 15 parts of the bighead atractylodes rhizome, 16 parts of Radix Codonopsis, 28 parts of cordate houttuynia, perilla leaf 10 parts, 20 parts of cassia twig, 18 parts of radix pseudostellariae, 15 parts of honeysuckle, 8 parts of schizonepeta, 10 parts of bulb of thunberg fritillary.
- 5. the preparation method of the composition that moistens the lung and relieve the cough any one of claim 1-4, it is characterised in that including following step Suddenly:1) various traditional Chinese medicinal components are respectively crushed into various corresponding medicinal powder;2) medicinal powder of step 1) is stirred, adds the 6-10 times of ethanol measured, soaked 8-12 days, heating extraction, contained The mixed liquor of effective component of chinese medicine;3) mixed liquor is centrifuged, filtered, removed the dregs of a decoction, obtain filtrate;4) filtrate is concentrated in vacuo, obtains concentrate;5) concentrate is dried in vacuo, obtains the composition that moistens the lung and relieve the cough.
- 6. preparation method according to claim 5, it is characterised in that the particle diameter of the medicinal powder in step 1) is 20-80 mesh.
- 7. preparation method according to claim 5, it is characterised in that in step 2), heating extraction concrete operations are:Heating Extraction 2-3 times, each 1-2h, extract solution and the dregs of a decoction are obtained, merge extract solution;10-12 times of decocting is added to boil twice the dregs of a decoction again, every time 1.5-3h, filtering, merge decoction liquor, the extract solution after merging is well mixed with the decoction liquor merged, obtains mixed liquor.
- 8. preparation method according to claim 5, it is characterised in that in step 3), the condition control of centrifugation is:From Heart time 8-15min, centrifuge speed 3000-6000r/min;In step 4), the vacuum degree control of vacuum concentration is -0.02 ~-0.08MPa, the density of concentrate is 1.2-1.6Kg/m3;In step 5), vacuum drying vacuum degree control be -0.03~- 0.1MPa, temperature are 50-80 DEG C, drying time 10-18h.
- The preparation 9. one kind moistens the lung and relieve the cough, it is characterised in that the preparation that moistens the lung and relieve the cough is included any one of claim 1-4 Moisten the lung and relieve the cough composition and pharmaceutically acceptable carrier.
- 10. the preparation according to claim 9 that moistens the lung and relieve the cough, it is characterised in that the preparation that moistens the lung and relieve the cough is pill, dissipated Agent, tablet, granule or capsule.
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