CN1071586A - 作药物用的突变生长因子受体及其治疗癌的应用 - Google Patents

作药物用的突变生长因子受体及其治疗癌的应用 Download PDF

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Publication number
CN1071586A
CN1071586A CN 92111396 CN92111396A CN1071586A CN 1071586 A CN1071586 A CN 1071586A CN 92111396 CN92111396 CN 92111396 CN 92111396 A CN92111396 A CN 92111396A CN 1071586 A CN1071586 A CN 1071586A
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CN
China
Prior art keywords
receptor
cell
mutation
egf
growth factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 92111396
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English (en)
Chinese (zh)
Inventor
A·乌尔里克
N·H·雷德曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
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Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Max Planck Gesellschaft zur Foerderung der Wissenschaften eV filed Critical Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Publication of CN1071586A publication Critical patent/CN1071586A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN 92111396 1991-09-05 1992-09-05 作药物用的突变生长因子受体及其治疗癌的应用 Pending CN1071586A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4129533.1 1991-09-05
DE19914129533 DE4129533A1 (de) 1991-09-05 1991-09-05 Mutierter wachstumsfaktorrezeptor als arzneimittel und seine verwendung zur behandlung von krebs

Publications (1)

Publication Number Publication Date
CN1071586A true CN1071586A (zh) 1993-05-05

Family

ID=6439926

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 92111396 Pending CN1071586A (zh) 1991-09-05 1992-09-05 作药物用的突变生长因子受体及其治疗癌的应用

Country Status (12)

Country Link
EP (1) EP0667899A1 (ja)
JP (1) JPH07502884A (ja)
CN (1) CN1071586A (ja)
AU (1) AU669857B2 (ja)
CA (1) CA2117073A1 (ja)
DE (1) DE4129533A1 (ja)
FI (1) FI941053A (ja)
MX (1) MX9205084A (ja)
NO (1) NO940778L (ja)
NZ (1) NZ244239A (ja)
PT (1) PT100844A (ja)
WO (1) WO1993005148A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465623B2 (en) 1995-05-02 2002-10-15 Garvan Institute Of Medical Research GDU, a novel signalling protein
AUPN274295A0 (en) * 1995-05-02 1995-05-25 Garvan Institute Of Medical Research GDU, a novel signalling protein
US6790614B1 (en) 1999-11-19 2004-09-14 Novartis Ag Selectable cell surface marker genes
BRPI0508286B8 (pt) 2004-03-31 2021-05-25 Dana Farber Cancer Inst Inc método para determinar a probabilidade de eficácia de um inibidor da tirosina quinase egfr para tratar câncer, uso de um inibidor da tirosina quinase de egfr, sonda, kit, e, par de iniciadores

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68926888T2 (de) * 1988-01-22 1997-01-09 Zymogenetics Inc Verfahren zur Herstellung von sekretierten Rezeptoranalogen
WO1990008160A1 (en) * 1989-01-20 1990-07-26 Imperial Cancer Research Technology Ltd. Growth factor receptor-like peptides without tyrosine-kinase activity
GB9001466D0 (en) * 1990-01-23 1990-03-21 Erba Carlo Spa Extracellular form of the human fibroblast growth factor receptor
DE69031120T2 (de) * 1989-05-19 1998-01-15 Genentech Inc Her2 extrazellulare domäne
WO1991003489A1 (en) * 1989-09-08 1991-03-21 The Johns Hopkins University Structural alterations of the egf receptor gene in human gliomas

Also Published As

Publication number Publication date
WO1993005148A1 (de) 1993-03-18
AU2518592A (en) 1993-04-05
FI941053A (fi) 1994-04-08
EP0667899A1 (de) 1995-08-23
MX9205084A (es) 1993-05-01
DE4129533A1 (de) 1993-03-11
AU669857B2 (en) 1996-06-27
NO940778D0 (no) 1994-03-04
FI941053A0 (fi) 1994-03-04
JPH07502884A (ja) 1995-03-30
CA2117073A1 (en) 1993-03-18
PT100844A (pt) 1994-05-31
NO940778L (no) 1994-05-04
NZ244239A (en) 1995-07-26

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C01 Deemed withdrawal of patent application (patent law 1993)