CN107158233A - A kind of externally applied drug for being used to treat burn wound - Google Patents
A kind of externally applied drug for being used to treat burn wound Download PDFInfo
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- CN107158233A CN107158233A CN201710328942.6A CN201710328942A CN107158233A CN 107158233 A CN107158233 A CN 107158233A CN 201710328942 A CN201710328942 A CN 201710328942A CN 107158233 A CN107158233 A CN 107158233A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/648—Myriapods, e.g. centipedes or millipedes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- Insects & Arthropods (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of externally applied drug for being used to treat burn wound, it is prepared from by following medicinal material：The bletilla striata, Artemisia stelleriana, the root of herbaceous peony, Chinese mugwort, PORIA ALBA, centipede, Chinese juniper, cloves, Asian puccoon in thousand；Rationally, all medicines share plays antipruritic to the drug component compatibility of the present invention altogether, and removing toxic substances is drawn out the pus, blood activating and promoting tissue regeneration, and the effect of restraining wound can effectively facilitate the recovery of burn wound.The present invention is applied to treatment burn wound.
Description
Technical field
The invention belongs to external Chinese medicament field, it is related to a kind of externally applied drug for being used to treat burn wound.
Background technology
Deep burn wound can not heal in a short time, or because burn of the infection without first intention, needs debridement, anti-sense
The surface of a wound of the complex treatments such as dye, skin-grafting, referred to as residual burn wound.Residual burn wound is clinically very common, mostly occurs
It is very fragile in the later stage of various depth of burn or newborn epithelium, not rub resistance, and formed and multiple be dispersed in the surface of a wound, or functional training
The small surface of a wound is formed after producing bubble ulceration, though this surface of a wound is handled through various measures, is not recovered for a long time still, even serious danger when serious
And patient vitals.
At present, the origin cause of formation of residual wound mainly has following several：
1. skin graft is not enough, and autologous skin source is limited after extensive deep burn, and self-skin transplant density is not enough or after skin-grafting because of other
Reason skin graft is not survived, and causes skin graft to fail to spread flap coverage；
2. refractory infection, because the course of disease is long, the application of antibiotic repeatedly causes surface of a wound bacterium severe infections and antibody-resistant bacterium
Occur, the false monospore of the staphylococcus aureus of current methicillin-resistant, Meticillin Coagulase Negative Staphylococcus, verdigris
Bacterium, Acinetobacter bauamnnii, infection have elevated trend.Bacterium and its metabolite hinder and suppress the growth of epithelium；
3. newborn epithelium is not wear-resisting, thin skin in new life, and abrasion-resistant, does not form the small surface of a wound easily；
4. local blood fortune is poor, and long-term bed does not get enough athletic exercise, and muscular atrophy can cause venous return obstacle, or part after cicatrization
Blood fortune is also poor.The position surface of a wound of blood fortune difference does not recover for a long time；
5. at surface of a wound local factor, the secretion inadequate drainage formation abscess ulceration or the surface of a wound of surface of a wound remnants sebaceous glands, sweat gland etc.
Formed a scab after reason, but inadequate drainage causes subinfection again and causes the surface of a wound to fester and do not recover for a long time under scab；
6. the influence of systemic factor, the long-term surface of a wound of patient oozes out and causes malnutrition, immunity degradation, microelement deficiencies
Or when being associated with the deelines such as diabetes, tuberculosis, can cause the surface of a wound not recover for a long time.
The content of the invention
The present invention is intended to provide a kind of be used to treat the externally applied drug of burn wound, by substantial amounts of experimental selection it is suitable in
Medicinal material and its proportioning, can purpose that is quick, effectively facilitating residual burn wound recovery.
In order to achieve the above object, the present invention is as follows using following technical scheme：
A kind of externally applied drug for being used to treat burn wound, in parts by weight, it includes following component：
10 parts of the bletilla striata, 10 parts of Artemisia stelleriana, 5 parts of the root of herbaceous peony, 5 parts of Chinese mugwort, 5 parts of PORIA ALBA, 2 parts of centipede, 5 parts of Chinese juniper, 3 parts of cloves, purple in thousand
5 parts of grass.
Beneficial effects of the present invention are as follows：Rationally, all medicines share plays antipruritic to the drug component compatibility of the present invention altogether,
Removing toxic substances is drawn out the pus, blood activating and promoting tissue regeneration, the effect of restraining wound, can effectively facilitate the recovery of burn wound.
The present invention is applied to treatment burn wound.
Embodiment
The present invention is described in further detail below in conjunction with specific embodiments.
A kind of externally applied drug for being used to treat burn wound of embodiment 1
The present embodiment is a kind of externally applied drug for being used to treat burn wound, and it includes following component：
Bletilla striata 10g, the g of Artemisia stelleriana 10, the g of the root of herbaceous peony 5,5 g of Chinese mugwort, the g of PORIA ALBA 5, the g of centipede 2, the g of Chinese juniper 5, the g of cloves 3, Asian puccoon in thousand
5 g。
Application method：After the Chinese herbal medicine that the present embodiment is provided is mixed, mash, be prepared into pasty state, standby, cleaning wound
Face, washs away dirt and crust, with normal saline flushing it is clean after, in the Chinese herbal medicine of surface of a wound external application the present embodiment.
The typical case of embodiment 2
1st, general information
Applicant collects patient 40 altogether, wherein man 20, female 20.Age reckling 14 years old, it is maximum 56 years old.
Wherein：Electric injury 4, boiling water scalds 2:0, flame burn 10, electric arc burn 6.
Residual wound position：Chest and back 8,7, upper limbs, 17, lower limb, four limbs have 8 entirely.
Maximum area 13cm × 15cm, 1 cm of minimum area × 1cm.
The surface of a wound festers repeatedly before treatment, most long 65d, most short 13 d.
Inclusive criteria：1. age 14 ~ 56 years old；2. this experimental therapy is voluntarily received.
Exclusion standard：1. radiation burn patient；2. the heart, brain, liver, IIR, disease of hematopoietic system and mental disease are merged
Patient；3. pregnant woman, women breast-feeding their children and allergic constitution person.
2nd, test method
All patients are first with 1：1000 bromogeramines clean the surface of a wound, wash away dirt and crust, clean with normal saline flushing
Afterwards, in surface of a wound external application the present embodiment 1 prepare Chinese herbal medicine, then wrapped up using sterile gauze external application, daily dressing once, 2 weeks
For a course for the treatment of.Curative effect is counted after one course for the treatment of.
3rd, criterion of therapeutical effect and treatment results
Curative effect judging standard is as follows：
Invalid, residual wound healing area is less than 40%, or the surface of a wound is unchanged after dressing or even deteriorates；
Effectively, residual wound healing area 40%~90%；
Effective, residual wound healing area is more than 90%.
Treatment statistics are as follows：
It can be seen that, medicine produced by the present invention can safely and effectively be used for the treatment of residual burn wound.
Above-described embodiment, is only presently preferred embodiments of the present invention, is not other forms made for the present invention
Limit, any those skilled in the art are changed or be modified as enlightenment possibly also with above-mentioned technology contents equivalent
The equivalent embodiment of change.In every case it is the technical spirit without departing from the claims in the present invention, the letter to made by above example
Single modification, equivalent variations and remodeling, still fall within the scope of the claims in the present invention protection.
Claims (1)
1. a kind of externally applied drug for being used to treat burn wound, it is characterised in that in parts by weight, it includes following component：
10 parts of the bletilla striata, 10 parts of Artemisia stelleriana, 5 parts of the root of herbaceous peony, 5 parts of Chinese mugwort, 5 parts of PORIA ALBA, 2 parts of centipede, 5 parts of Chinese juniper, 3 parts of cloves, purple in thousand
5 parts of grass.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710328942.6A CN107158233A (en) | 2017-05-11 | 2017-05-11 | A kind of externally applied drug for being used to treat burn wound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710328942.6A CN107158233A (en) | 2017-05-11 | 2017-05-11 | A kind of externally applied drug for being used to treat burn wound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107158233A true CN107158233A (en) | 2017-09-15 |
Family
ID=59815869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710328942.6A Withdrawn CN107158233A (en) | 2017-05-11 | 2017-05-11 | A kind of externally applied drug for being used to treat burn wound |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107158233A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104721564A (en) * | 2015-03-19 | 2015-06-24 | 烟台毓璜顶医院 | Externally applied agent for treating residual burn wounds |
-
2017
- 2017-05-11 CN CN201710328942.6A patent/CN107158233A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104721564A (en) * | 2015-03-19 | 2015-06-24 | 烟台毓璜顶医院 | Externally applied agent for treating residual burn wounds |
Non-Patent Citations (2)
| Title |
|---|
| 郭惠玲，等: "烫伤灵对小鼠抗炎、镇痛作用的实验研究", 《陕西中医学院学报》 * |
| 黄跃生等: "《烧伤关键治疗技术及预防急救指南》", 30 June 2015, 人民军医出版社 * |
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|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170915 |