CN107137645A - 一种男性用补肾阳滋肾阴的中药膏服剂及其制备方法 - Google Patents

一种男性用补肾阳滋肾阴的中药膏服剂及其制备方法 Download PDF

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CN107137645A
CN107137645A CN201710381115.3A CN201710381115A CN107137645A CN 107137645 A CN107137645 A CN 107137645A CN 201710381115 A CN201710381115 A CN 201710381115A CN 107137645 A CN107137645 A CN 107137645A
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kidney
yin
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璧甸福
赵一鸣
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Chengdu Six Tang Institute Of Probiotics
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Abstract

本发明公开了一种男性用补肾阳滋肾阴的中药膏服剂，包括菟丝子，山茱萸，人参，鹿角胶，女贞子，熟地黄，枸杞子，黄精，仙灵脾，炒白术，当归，仙茅，山药，炒杜仲，益智仁，锁阳，天冬，白芨，炙黄芪，巴戟天，川断，丹参和怀牛膝；本发明通过以川断、丹参、怀牛膝、炙黄芪、熟地黄、菟丝子和天冬为主药，配以黄精、仙灵脾、仙茅、炒杜仲、益智仁和锁阳为辅药，使男性食用后，能够滋肾养阴，大补肾气，充精填髓；治疗肾水不足，真阴亏损，腰膝酸软，形体羸弱，自汗盗汗，精液虚少，少精弱精，不孕不育，性欲低下，阳萎早泄，精液清冷、阳举不坚、射精乏力、晨勃稀少，夜尿痰多，头晕耳鸣，精神不振；乌须发悦颜色，生发润发。

Description

一种男性用补肾阳滋肾阴的中药膏服剂及其制备方法
技术领域
本发明属于含有抗原或抗体的医药配制品的技术领域，具体是涉及一种男性用补肾阳滋肾阴的中药膏服剂及其制备方法。
背景技术
肾虚指肾脏精气阴阳不足,肾虚的种类有很多，其中最常见的是肾阴虚、肾阳虚：肾阳虚表现为腰膝酸痛、筋骨萎软、神疲乏力、身体沉重、性欲减退、性功能低下、手足冰冷、畏寒怕风、易受凉腹泻、身体浮肿等等；此外女子肾阳虚会出现遗尿等症状。补肾阳虚的药物多是温热性药物，如附子、肉桂、鹿茸、巴戟天、金樱子等。肾阴虚的主要症状是腰膝酸软、两腿无力、心烦易怒，还会有以下症状：眩晕耳鸣、形体消瘦、失眠多梦、颧红潮热、盗汗、咽干、男子阳痿或阳强不倒、性欲亢进、遗精早泄、妇女经少、经闭等等。补肾阴虚的药物有制首乌、桑椹、熟地黄、龟甲胶、女贞子、黄精、墨旱莲、枸杞子、石斛、玉竹、山茱萸、西洋参等，中成药的代表是六味地黄丸、左归丸、七宝美髯丹等等。
现代科学证明，当人发生肾虚时，无论肾阴虚还是肾阳虚，都会导致人的免疫能力的降低；有更多证据表明，肾虚发生时，肾脏的免疫能力降低，肾脏的微循环系统亦会发生阻塞，肾络不通；因此对于肾虚的治疗应防治结合。
在现有技术中，已经公开了多种强调补肾的中药方剂、药物、保健食品，但大多仅针对肾阳虚，极少关注肾阴虚，导致组方阴阳失衡。专利申请号为CN96115423中国专利文献公开了一种治疗男科病的补肾壮阳散，由一定重量比的下述原料制成：淫洋火(羊油炙)、海马、甘草、山芋肉、巴吉天、寸云、麦冬、熟地、枸杞子、当归、白芍、补骨脂、杜仲、海狗肾、石菖卜、远志、朱砂、金樱子、覆盆子、车前子、阳起石、蜈蚣、附子、肉桂、鹿茸。虽然该专利宣称对治疗男科阳痿、早泄少精、无精等病症具有疗效快、疗效高等优点，但其所用原料药大多为补肾阳的温热性药物，长期服用可能导致阳气亢盛、阴津受损、热火内生，出现口干舌燥、鼻血、便秘等症状。专利申请号为的CN200410043608中国专利文献公开了一种补肾壮阳胶囊，由山萸肉30克、人参15克、淫洋藿20克、巴戟15克、锁阳25克、鹿茸5克、仙茅15克、肉苁蓉20克、蛇床子20克、肉桂5克、枸杞子25克、覆盆子20克、菟丝子15克、熟地20克研成粉末制备而成，也可制备成其它常用内服剂型。该发明宣称具有温补肾阳、填精补血、兴阳起痿的功能，用于补肾壮阳功效显著，但其组方同样阴阳失衡，久服对身体必有损伤；专利申请号为CN02144696.2的中国专利文献公开了一种滋阴补肾、益气健脾药物及制备方法，是以枸杞子、熟地黄、龟甲、人参、白术、山楂、鹿茸、淫羊藿、巴戟天、牛膝为原料，根据药材质地和药物有效成分不同，分别采取不同溶剂提取后，再经纯化、浓缩等工艺制成药物；虽然该发明组方较合理、严谨，但所采用的制备工艺相对复杂，导致成本难以控制。
发明内容
有鉴于此，本发明的目的在于提供一种男性用补肾阳滋肾阴的中药膏服剂及其制备方法，该一种男性用补肾阳滋肾阴的中药膏服剂通过以川断、丹参、怀牛膝、炙黄芪、熟地黄、菟丝子和天冬为主药，配以黄精、仙灵脾、仙茅、炒杜仲、益智仁和锁阳为辅药，再以人参、鹿角胶、女贞子枸杞子和当归为调和药性，使男性食用后，能够滋肾养阴，大补肾气，充精填髓；并且治疗肾水不足，真阴亏损，腰膝酸软，形体羸弱，自汗盗汗，精液虚少，少精弱精，不孕不育，性欲低下，阳萎早泄，精液清冷、阳举不坚、射精乏力、晨勃稀少，夜尿痰多，头晕耳鸣，精神不振；乌须发悦颜色，生发润发。
为了达到上述目的，本发明一种男性用补肾阳滋肾阴的中药膏服剂，包括主药、辅药和调和药，其中主药由以下重量份的原料药制成：菟丝子18～22份，熟地黄25～35份，炙黄芪20～30份，巴戟天12～16份，川断25～35份，丹参20～30份，天冬25～35份和怀牛膝18～22份；
辅药由以下重量份的原料药制成：黄精20～30份，山茱萸7～10份，仙灵脾12～16份，炒白术25～35份，炒杜仲12～16份，益智仁12～16份，锁阳10～14份，白芨20～30份；
调和药以下重量份的原料药制成：人参18～22份，鹿角胶18～22份，女贞子18～22份，当归18～22份，仙茅10～14份，山药18～22份，枸杞子25～35份。
进一步，各原料药的重量份分别是：菟丝子20份，山茱萸8份，人参20份，鹿角胶20份，女贞子20份，熟地黄30份，枸杞子30份，黄精25份，仙灵脾15份，炒白术30份，当归20份，仙茅12份，山药20份，炒杜仲15份，益智仁15份，锁阳12份，天冬30份，白芨25份，炙黄芪25份，巴戟天15份，川断30份，丹参25份，怀牛膝20份。
进一步，还添加有炼蜜冰糖、麦芽糖或者红糖。
本发明还公开了一种男性用补肾阳滋肾阴的中药膏服剂的制备方法，其步骤在于：
1)按照比例取主药成分菟丝子，熟地黄，炙黄芪，巴戟天，川断，丹参，天冬和怀牛膝混合后分三次以上煎成，经过滤去渣，再将各次所获药液混合于一处，慢火熬炼，熬至药液浓度黏稠，药液在匀内倒下时成线条状；
2)按照比例取调和药成分人参，鹿角胶，当归，仙茅，山药，女贞子和枸杞子，混水后进行高温熬煮，熬制稀烂后等温度降低至60±5℃加入主药药液进行搅拌混合；
3)按照比例取辅药成分黄精，山茱萸，仙灵脾，炒白术，炒杜仲，益智仁，锁阳和白芨，研磨成粉，将药粉混合后分二次以上煎成，经过滤去渣，再将各次所获药液混合于一处，慢火熬炼，熬至药液浓度黏稠，药液在匀内倒下时成线条状，然后让其自然冷却，等药液温度冷却至60±5℃后,倒入主药药液中进行搅拌混合。
进一步，第2)和第3)步骤之间间隔时间不超过10分钟。
进一步，在第3)步骤中，主药、辅药和调和药混合后，将温度加热到80～90℃后添加炼蜜冰糖、麦芽糖或者红糖中任一一种或两种，在80～90℃混合搅拌10～15分钟，直至药液成膏状。
川断：补肝肾，续筋骨，调血脉；治腰背酸痛，足膝无力，胎漏，崩漏，带下，遗精；
丹参：活血祛瘀，通经止痛，清心除烦，凉血消痈；
怀牛膝：活血散瘀，祛湿利尿，清热解毒；
炙黄芪：益气补中，用于气虚乏力；
熟地黄：补血滋阴，益精填髓；主治肝肾阴虚，腰膝酸软，骨蒸潮热，盗汗遗精，内热消渴；
菟丝子：补肾、肝、脾之良药，主治肾虚腰痛、阳痿遗精、尿频；
天冬：养阴生津，白喉；败毒抗癌，清势化痰、滋阴润燥。
本发明的有益效果在于：
1、本发明一种男性用补肾阳滋肾阴的中药膏服剂通过以川断、丹参、怀牛膝、炙黄芪、熟地黄、菟丝子和天冬为主药，配以黄精、仙灵脾、仙茅、炒杜仲、益智仁和锁阳为辅药，再以人参、鹿角胶、女贞子枸杞子和当归为调和药性，使男性食用后，能够滋肾养阴，大补肾气，充精填髓；并且治疗肾水不足，真阴亏损，腰膝酸软，形体羸弱，自汗盗汗，精液虚少，少精弱精，不孕不育，性欲低下，阳萎早泄，精液清冷、阳举不坚、射精乏力、晨勃稀少，夜尿痰多，头晕耳鸣，精神不振；乌须发悦颜色，生发润发；
2、本发明一种男性用补肾阳滋肾阴的中药膏服剂中人参、女贞子、熟地黄、枸杞子、黄精、炒白术、当归、山药、天冬、白芨、炙黄芪、巴戟天、丹参、怀牛膝均可以作为药品，又可以作为食品，不仅材料来源方便，通过服食后，药效吸收快，效果好，副作用少，价格相对比较便宜。
具体实施方式
实施例1
称取主药成分菟丝子18g，熟地黄25g，炙黄芪20g，巴戟天12g，川断25g，丹参20g份，天冬25g和怀牛膝18g混合后分三次以上煎成，经过滤去渣，再将各次所获药液混合于一处，慢火熬炼，熬至药液浓度黏稠，药液在匀内倒下时成线条状；称取调和药成分人参18g，鹿角胶18g，女贞子18g，当归18g，仙茅10g，山药18g，枸杞子25g，混水后进行高温熬煮，熬制稀烂后等温度降低至55℃加入主药药液进行搅拌混合；称取辅药成分黄精20g，山茱萸7g份，仙灵脾12g，炒白术25g，炒杜仲12g，益智仁12g，锁阳10g，白芨20g，研磨成粉，将药粉混合后分二次以上煎成，经过滤去渣，再将各次所获药液混合于一处，慢火熬炼，熬至药液浓度黏稠，药液在匀内倒下时成线条状，然后让其自然冷却，等药液温度冷却至60±5℃后,倒入主药混合药液中进行搅拌混合，主药、辅药和调和药混合后，将温度加热到80℃后添加炼蜜冰糖和麦芽糖，在80℃混合搅拌10分钟，直至药液成膏状。
实施例2
称取主药成分菟丝子20g，熟地黄30g，炙黄芪25g，巴戟天15g，川断30g，丹参25g，天冬30g和怀牛膝20g混合后分三次以上煎成，经过滤去渣，再将各次所获药液混合于一处，慢火熬炼，熬至药液浓度黏稠，药液在匀内倒下时成线条状；称取调和药成分人参20g，鹿角胶20g，女贞子20g，当归20g，仙茅12g，山药20g，枸杞子30g，混水后进行高温熬煮，熬制稀烂后等温度降低至60℃加入主药药液进行搅拌混合；称取辅药成分黄精25g，山茱萸8g，仙灵脾15g，炒白术30g，炒杜仲14g，益智仁14g，锁阳12g，白芨25g，研磨成粉，将药粉混合后分二次以上煎成，经过滤去渣，再将各次所获药液混合于一处，慢火熬炼，熬至药液浓度黏稠，药液在匀内倒下时成线条状，然后让其自然冷却，等药液温度冷却至60℃后,倒入主药药液中进行搅拌混合，主药、辅药和调和药混合后，在85℃混合搅拌13分钟，直至药液成膏状。
实施例3
称取主药成分菟丝子22g，熟地黄35g，炙黄芪30g，巴戟天16g，川断35g，丹参30g，天冬35g和怀牛膝22g混合后分三次以上煎成，经过滤去渣，再将各次所获药液混合于一处，慢火熬炼，熬至药液浓度黏稠，药液在匀内倒下时成线条状；称取调和药成分人参22g，鹿角胶22g，女贞子22g，当归22g，仙茅14g，山药22g，枸杞子35g，混水后进行高温熬煮，熬制稀烂后等温度降低至65℃加入主药药液进行搅拌混合；称取辅药成分黄精30g，山茱萸10g，仙灵脾16g，炒白术35g，炒杜仲16g，益智仁16g，锁阳14g，白芨30g，研磨成粉，将药粉混合后分二次以上煎成，经过滤去渣，再将各次所获药液混合于一处，慢火熬炼，熬至药液浓度黏稠，药液在匀内倒下时成线条状，然后让其自然冷却，等药液温度冷却至65℃后,倒入主药药液中进行搅拌混合，主药、辅药和调和药混合后，将温度加热到80～90℃后添加红糖，在90℃混合搅拌15分钟，直至药液成膏状。
为了证明本发明具有很好的疗效，列举典型病例如下：
案例一
吴某某，男，60岁，四川省成都市人，农民，常感精神倦怠、腰酸背沉，小便无力，夜尿多，偶有身体浮肿症状；2016年12月开始食用实施例2配置制备的中药膏，每天2次，每次250g，连续吃7天为1个疗程，间隔3天；2个月后上述症状全部消失，自觉身体状况大有好转，至今依然经常服用。
案例二
高某，男，25岁，四川省成都市某高校硕士研究生，面色苍白，经常感觉全身乏力，并有频繁遗精症状；2016年3月开始食用实施例3配置制备的中药膏，每天1次，每次250g，连续吃7天为1个疗程，间隔3天；1个月后上述症状全部消失，面色转红润，乏力、遗精等症状基本消失。
案例三
王某某，男，44岁，四川省成都市人，公务员，39岁后即有腰膝酸软、神疲乏力、性欲减退、性功能低下症状；2016年6月开始食用实施例1配置制备的中药膏，每天2次，每次200g，连续吃7天为1个疗程，间隔3天；3个月后上述症状全部消失，腰膝酸软、神疲乏力症状消失，性欲、性能力大有改善。
案例四
罗某，男，45岁，四川省成都市人，私企业主，近年常感腰酸、头晕、耳鸣，伴有夜尿多、轻微阳痿症状。2016年12月开始食用实施例1配置制备的中药膏，每天2次，每次300g，连续吃7天为1个疗程，间隔3天；3个月后腰酸、头晕、耳鸣、夜尿多上述症状全部消失，腰膝酸软、神疲乏力症状消失，性欲、性能力大有改善，现仍继续服用。
案例五：
刘某某，男，32岁，四川省成都市人，国企员工，羸瘦，面色青白，畏寒，易出虚汗，有早泄症状，为典型的肾阳虚。2016年3月开始服用食用实施例1配置制备的中药膏，每天2次，每次200g，连续吃7天为1个疗程，间隔3天；3个月后腰酸、头面色青白，畏寒，易出虚汗，有早泄症状消失，性欲、性能力大有改善，现仍继续服用。
最后说明的是，以上优选实施例仅用以说明本发明的技术方案而非限制，尽管通过上述优选实施例已经对本发明进行了详细的描述，但本领域技术人员应当理解，可以在形式上和细节上对其作出各种各样的改变，而不偏离本发明权利要求书所限定的范围。

Claims (6)

1.一种男性用补肾阳滋肾阴的中药膏服剂，其特征在于：包括主药、辅药和调和药，其中主药由以下重量份的原料药制成：菟丝子18～22份，熟地黄25～35份，炙黄芪20～30份，巴戟天12～16份，川断25～35份，丹参20～30份，天冬25～35份和怀牛膝18～22份；
辅药由以下重量份的原料药制成：黄精20～30份，山茱萸7～10份，仙灵脾12～16份，炒白术25～35份，炒杜仲12～16份，益智仁12～16份，锁阳10～14份，白芨20～30份，
调和药以下重量份的原料药制成：人参18～22份，鹿角胶18～22份，女贞子18～22份，当归18～22份，仙茅10～14份，山药18～22份，枸杞子25～35份。
2.根据权利要求1所述的一种男性用补肾阳滋肾阴的中药膏服剂，其特征在于：各原料药的重量份分别是：菟丝子20份，山茱萸8份，人参20份，鹿角胶20份，女贞子20份，熟地黄30份，枸杞子30份，黄精25份，仙灵脾15份，炒白术30份，当归20份，仙茅12份，山药20份，炒杜仲15份，益智仁15份，锁阳12份，天冬30份，白芨25份，炙黄芪25份，巴戟天15份，川断30份，丹参25份，怀牛膝20份。
3.根据权利要求1所述的一种男性用补肾阳滋肾阴的中药膏服剂，其特征在于：还添加有炼蜜冰糖、麦芽糖或者红糖。
4.一种制备权利要求1～3任一项所述的一种男性用补肾阳滋肾阴的中药膏服剂的方法，其特征在于，其步骤如下：
1)按照比例取主药成分菟丝子，熟地黄，炙黄芪，巴戟天，川断，丹参，天冬和怀牛膝混合后分三次以上煎成，经过滤去渣，再将各次所获药液混合于一处，慢火熬炼，熬至药液浓度黏稠，药液在匀内倒下时成线条状；
2)按照比例取调和药成分人参，鹿角胶，当归，仙茅，山药，女贞子和枸杞子，混水后进行高温熬煮，熬制稀烂后等温度降低至60±5℃加入主药药液进行搅拌混合；
3)按照比例取辅药成分黄精，山茱萸，仙灵脾，炒白术，炒杜仲，益智仁，锁阳和白芨，研磨成粉，将药粉混合后分二次以上煎成，经过滤去渣，再将各次所获药液混合于一处，慢火熬炼，熬至药液浓度黏稠，药液在匀内倒下时成线条状，然后让其自然冷却，等药液温度冷却至60±5℃后,倒入主药药液中进行搅拌混合。
5.根据权利要求4所述的一种男性用补肾阳滋肾阴的中药膏服剂的方法，其特征在于：第2)和第3)步骤之间间隔时间不超过10分钟。
6.根据权利要求4所述的一种男性用补肾阳滋肾阴的中药膏服剂的方法，其特征在于：在第3)步骤中，主药、辅药和调和药混合后，将温度加热到80～90℃后添加炼蜜冰糖、麦芽糖或者红糖中任一一种或两种，在80～90℃混合搅拌10～15分钟，直至药液成膏状。
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