CN104352776A - 一种治疗月经过少致不孕的中药制剂及其制备方法 - Google Patents

一种治疗月经过少致不孕的中药制剂及其制备方法 Download PDF

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CN104352776A
CN104352776A CN201410742775.6A CN201410742775A CN104352776A CN 104352776 A CN104352776 A CN 104352776A CN 201410742775 A CN201410742775 A CN 201410742775A CN 104352776 A CN104352776 A CN 104352776A
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徐姝一
刘敏
汤玮
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Abstract

本发明公开了一种治疗月经过少致不孕的中药制剂,它是由枸杞子、沙苑子、菟丝子、女贞子、覆盆子、补骨脂、炙黄芪、续断、杜仲、骨碎补、巴戟天、淫羊藿、仙茅、当归、熟地黄、炒山药、党参、红景天、黄精、延胡索、丹参、茺蔚子、肉苁蓉、制何首乌按照一定的重量配比制成,具有补肾助阳,活血调经,散寒止痛,调理身体的功效,对于月经量少的具有显著提高受孕率的治疗效果。

Description

一种治疗月经过少致不孕的中药制剂及其制备方法
技术领域
[0001] 本发明涉及一种中药制剂,具体涉及一种治疗月经过少致不孕的中药制剂,本发 明还涉及该中药制剂的制备方法。
背景技术
[0002] 如今女性月经生活压力大大增加,月经不调也变成了常事,很多女性朋友非常担 心月经量少是不是疾病,会不会影响到生育问题,月经量少是指月经周期基本正常,月经血 量较常量明显减少,甚至点滴即净;或经期缩短不足两天,经量亦少的月经病。一般认为月 经血量每次不超过20ml,为月经过少。月经量少并不能说明女性缺乏生育能力,但是会对生 育造成一定的影响,如果不能及时治理调理,久而久之会直接导致不孕。
[0003] -般来说,月经量少是因为雌激素水平低所引起的。女性体内的雌激素会刺激子 宫内膜增生变厚,保证了胎儿的成长环境,为女性的受孕做准备。如果子宫受孕不成功,增 生的子宫内膜便会脱落随经血一同排出体外,形成月经。所以当体内雌激素水平达不到一 定程度的时候就会导致子宫内膜增生不足,月经时出血少。子宫内膜长期出现这种增生不 足,会导致子宫内膜变薄,这种情况日后会影响到受孕,情况严重的会导致不孕。
[0004] 中医学认为本病多因血虚、气滞、血瘀、寒凝血脉、痰阻等原因所致。中医采用补肾 活血法治疗本病具有独特的优势和丰富的经验,从根本上进行身体的调理,且临床疗效显 著,副作用较小。
发明内容
[0005] 本发明的目的在于提供一种治疗月经过少致不孕的中药制剂,该中药制剂对于月 经过少致不孕具有疗效确切,副作用小,服用方便,价格低廉,调理身体的特点。
[0006] 本发明的另一目的是提供该治疗月经过少致不孕的中药制剂的制备方法。
[0007] 发明人在多年的临床医疗实践中,观察到月经过少致不孕给患者带来的身体和心 里上的压力,根据该病症的发展规律,以及中药的配伍原则,并通过大量的临床验证,反复 探索总结出一种治疗月经过少致不孕的中药制剂的新配方,本发明选择枸杞子、沙苑子、菟 丝子、女贞子、覆盆子、补骨脂、炙黄芪、续断、杜仲、骨碎补、巴戟天、淫羊藿、仙茅、当归、熟 地黄、炒山药、党参、红景天、黄精、延胡索、丹参、茺蔚子、肉苁蓉、制何首乌进行组合,将这 些药物组合使得各药物功效产生协同作用,使之具有补肾助阳,活血调经,散寒止痛,调理 身体的功效,从而能够有效治疗月经过少致不孕。
[0008] 本发明中药物的作用: 其中: 枸杞子:为爺科植物宁夏枸杞Lycium barbarum L.的干燥成熟果实。性味甘;平。归 肝、肾、肺经。功效:养肝;滋肾;润肺。主治:肝肾亏虚;头晕目眩;目视不清;腰膝酸软;阳 痿遗精;虚劳咳嗽;消渴引饮。枸杞提取液具有延缓衰老作用和补肾功能。
[0009] 沙苑子:为豆科植物扁莖黄苗Astragalus complanatus R. Brown.的干燥成熟种 子。性味温,甘。归肝、肾经。功效:功效:温补肝肾,固精,缩尿,明目。用于肾虚腰痛,遗精 早泄,白浊带下,小便余浙,眩晕目昏。《顾氏医镜》云:本品"强阴固精、功专补肾。"沙苑子 益精而不乱阳,补阳而不乱身。
[0010] 宽丝子:为双子叶植物药旋花科植物宽丝子Cuscuta chinensis Lam.的干燥成 熟种子。性味辛、甘、平。归肝、肾经。功效:补肝肾,益精髓,安胎,明目,止泻。适用于肝 肾不足的腰膝筋骨酸痛,腿脚软弱无力、阳痿遗精、呓语、小便频数、尿有余浙、头晕眼花、视 物不清、耳鸣耳聋以及妇女带下、习惯性流产等症。菟丝子即可补阳,又可益阴,具有温而不 燥,补而不滞的特点,为平补肝肾之良药。常配枸杞子,五味子等。对内分泌的作用:菟丝子 可以增加下丘脑-垂体-卵巢促黄体功能。
[0011] 女贞子:为双子叶植物药木犀科植物女贞的果实。性味:苦、甘、平、无毒。归肝, 肾,肺经。功效:补肝肾,强腰膝。主治:阴虚内热,头晕,目花,耳鸣,腰膝酸软,须发早白。
[0012] 覆盆子:为蔷薇科悬钩子属植物华东覆盆子Rubus chingii Hu的干燥果实。性 味:甘、酸、温。归经:入肝、肾经。功效:补肾固精,助阳明目。主治:阳痿、遗精遗尿,小便 频数,眼目昏花。《本草述》中记载:覆盆子,方书用之治劳倦虚劳等证,或补肾元阳,或益肾 阴气,或专滋精血,随其所宜之主,皆能相助为理也。
[0013] 补骨脂:为豆科植物补骨脂Psoralea corylifolia L.的干燥成熟果实。性味 辛、苦;温。归肾、心包、脾、胃、肺经。功效:补肾助阳;纳气平喘;温脾止泻。本品能补肾阳、 暖脾阳,止泄泻,为治脾肾阳虚之要药。本品辛苦温燥,能温补命门,补肾强腰,壮阳、固精、 缩尿,为治肾阳不足、下元不固之要药。
[0014] 炎黄苗:为豆科植物蒙古黄苗 Astragalus membranaceus (Fisch. ) Bge. var. mongholicus (Bge. ) Hsiao 或膜荚黄苗 Astragalus membranaceus (Fisch. ) Bge.的干 燥根。性味:甘,微温。归肺、脾、肝、肾经。功效:补气升阳、固表敛汗、利水消肿、托疮排脓、 通调水道。黄芪擅长补中益气,为补气升阳的要药,并且温阳补肾。
[0015] 续断:为川续断科植物川续断 Dipsacus asperoides C. Y. Cheng et T. M. Ai 的干燥根。性味苦、辛,微温。归肝、肾经。功效:补肝肾;强筋骨;调血脉;续折伤;止崩漏。 续断有排脓、止血、镇痛、促进组织再生的作用。本品甘温助阳,辛温散寒,用治肾阳不足,下 元虚冷,阳痿不举,遗精滑泄,遗尿尿频等症,兼有补益肝肾,强健壮骨,通利血脉之功。常与 肉苁蓉,菟丝子等壮阳药同用。
[0016] 杜仲:为杜仲科植物杜仲(Eucommia ulmoides Oliver)的干燥树皮。性味甘、微 辛,温。归肝、肾经。功效:补肝肾、强筋骨、降血压、安胎。
[0017] 骨碎补:为水龙骨科植物槲蕨Drynaria fortunei (Kunze) J. Sm.的干燥根莖。 性味苦,温。归肾、肝经。功效:补肾强骨,续伤止痛。用于肾虚腰痛,耳鸣耳聋,牙齿松动, 跌扑闪挫,筋骨折伤。
[0018] 巴戟天:为双子叶植物药茜草科植物巴戟天Morinda officinalis How的干燥根。 性味:辛,甘;微温。归肾经、肝经。功效:补肾助阳,祛风除湿,强筋健骨。巴戟天甘辛性温, 甘温能补,辛温能润,能温肾壮阳益精,常配淫羊藿、仙茅。
[0019] 淫羊藿:为小檗科植物淫羊藿(Epimedium brevicornum Maxim.)、箭叶淫羊藿 (Epimedium sagittatumMaxim.)、柔毛淫羊藿(Epimedium pubescens Maxim.)、或卓月鲜淫 羊藿(Epimediumkoreanum Nakai)的干燥叶。性味辛、甘,温。归肝、肾经。功效:补肾阳, 强筋骨,祛风湿。淫羊藿提取液能提高机体免疫功能,特别是对肾虚病人免疫功能低下有改 善作用。
[0020] 仙茅:为石蒜科植物仙茅Curculigo orchioides Gaertn.的干燥根莖。性味辛, 温,有毒。归肾、肝经。功效:补肾助阳、益精血、强筋骨、行血消肿。仙茅根茎乙醇提取物 具有雌激素样活性。仙茅水提取液有兴奋性机能的作用。仙茅有增强免疫功能的作用。仙 茅辛热,能补肾阳,兴阳道,止遗尿,常与淫羊藿、菟丝子同用。淫羊藿辛甘性温,温燥之性较 强,补名门之火,祛风湿疏通络作用突出,长于治疗风湿痹痛,四肢麻木等,仙茅辛热有毒, 暖腰膝、祛寒湿作用突出。仙茅与淫羊藿相须为用温阳补肾,用于肾阳不足、命门火衰的阳 痿精冷,以及肾虚腰膝痿软,筋骨冷痛。
[0021] 当归:为伞形科植物当归Angelica sinensis (Oliv. ) Diels的干燥根。性味 甘、辛、苦,温。归肝、心、脾经。功效:补血;活血;调经止痛;润燥滑肠。"黄芪与当归,有相 须之理。"黄芪大补肺脾之气,有固外之能;当归益血和营,是血家气药,以辛升运行为用,以 温和辛润为功。二味合之,便能阳生阴长。
[0022] 熟地黄:为玄参科植物地黄(Rehmannia glutinosa(Gdertn) Iibosch. ex Fisch. et Mey.)的块根经加工炮制而成。性味:甘、微温。归肝、肾经。功效:滋阴补血,益精填 髓。用于肝肾阴虚,腰膝酸软,骨蒸潮热,盗汗遗精,内热消渴,血虚萎黄,心悸怔忡,月经不 调,崩漏下血,眩晕,耳鸣,须发早白。熟地能补血滋阴而养肝益肾,凡血虚阴亏、肝肾不足所 致的眩晕,均可应用。
[0023] 炒山药:为薯截科植物薯截Dioscorea opposita Thunb.的干燥根莖。性味平, 甘。归脾、肺、肾经。功效:补脾养胃,生津益肺,补肾涩精。用于脾虚食少,久泻不止,肺虚 喘咳,肾虚遗精,带下,尿频,虚热消渴。
[0024] 党参:为桔梗科植物党参Codonopsis pilosula (Franch. ) Nannf.、素花党参 Codonopsis pilosula Nannf. var. modesta (Nannf. ) L. T. Shen 或川党参 Codonopsis tangshen Oliv.的干燥根。性味:甘、平。归脾、肺经。功效:补益脾肺,养血生津。用于脾 肺虚弱、气短、心悸、食少便溏、虚喘咳嗽,内热消渴等。《本草从新》记载:补中益气、和脾胃、 除烦渴。中气微弱,用以调补,甚为平妥。
[0025] 红景天:为景天科红景天属植物红景天Rhodiola saera (Prain) Fu,以全草入 药。性味:甘、涩,寒。功效:补气清肺;益智养心;收涩止血;散瘀消肿。主气虚体弱;病后 畏寒;气短乏力;肺热咳嗽;咯血;白带腹泻;跌打损伤;烫火伤;神经症;高原反应。
[0026] 黄精:为百合科植物漠黄精 Polygonatum kingianum Coll, et Hemsl.、黄精 Polygonatum sibiricum Red.或多花黄精 Polygonatum cyrtonema Hua 的干燥根莖。性 味:甘,平。归脾、肺、肾经。功效:补气养阴,健脾,润肺,益肾。用于脾胃虚弱,体倦乏力,口 干食少,肺虚燥咳,精血不足,内热消渴。《本草便读》:黄精,为滋腻之品,久服令人不饥,若 脾虚有湿者,不宜服之,恐其腻膈也。此药味甘如饴,性平质润,为补养脾阴之正品。
[0027] 延胡索:为S粟科植物延胡索Corydalis yanhusuo W. T. Wang的干燥块莖。性 味:辛、苦、温。归肝、脾经。功效:活血,利气,止痛。用于胸胁、脘腹疼痛,经闭痛经,产后瘀 阻,跌扑肿痛。本品辛散温通,能行血中气滞,气中血滞,活血行气止痛,善治血瘀气滞所致 的多种疼痛,其止痛作用优良。《本草求真》中记载:延胡索,不论是血是气,积而不散者,月艮 此力能通达,以其性温,则于气血能行能畅,味辛则于气血能润能散,所以理一身上下诸痛, 往往独行功多。
[0028] 丹参:为双子叶植物唇形科Labiatae鼠尾草属植物丹参Salvia miItiorrhiza Bge.的干燥根及根茎。性味苦,微寒。入心、肝经。功效:活血调经,祛瘀止痛,凉血消痈, 清心除烦,养血安神。用于胸肋胁痛,风湿痹痛,症瘕结块。《日华子本草》:养神定志,通利 关脉。治冷热劳,骨节疼痛,四肢不遂;排脓止痛,生肌长肉;破宿血,补新生血;安生胎,落 死胎;止血崩带下,调妇人经脉不匀,血邪心烦;恶疮疥癣,瘿赘肿毒,丹毒;头痛,赤眼,热 温狂闷。
[0029] 竞蔚子:为唇形科植物益母草Leonurus japonicus Houtt.的干燥成熟果实。性 味:辛、苦,微寒。归心包、肝经。功效:活血调经,清肝明目。用于月经不调,经闭,痛经,目 赤翳障,头晕胀痛。古人记载:茺蔚子,活血行气,有补阴之功,故名益母。凡胎前产后所恃 者,血气也。胎前无滞,产后无虚,以其行中有补也。
[0030] 肉灰蓉:本品为列当科一年生寄生草本植物肉灰蓉Cistanche deserticola Y.C.Ma的干燥带鳞叶的肉质茎。性味:甘、咸、温。归肾、大肠经。功效:补肾阳,益精血,润 肠通便。肉苁蓉能补肾阳,益精血,暖腰膝。用于肾阳不足、精血亏虚所致的筋骨痿软,腰膝 酸冷。《本草经疏》中记载:肉苁蓉,滋肾补精血之要药,气本微温,相传以为热者误也。甘 能除热补中,酸能入肝,咸能滋肾,肾肝为阴,阴气滋长,则五脏之劳热自退,久服则肥健而 轻身,益肾肝补精血之效也。
[0031] 制何首乌:为寥科植物何首乌Polygonum multiflorum Thunb.的干燥块根。性 味:苦、甘、涩、微温。归肝、心、肾经。功效:补血生精,解毒消痈,润肠通便。制何首乌味甘 主补,长于补肝血,益肾精,强筋骨。发为血之余,肾之所荣,精血得充,则善乌须发。制何首 乌,肾主冲任,肝司学海,补肝益肾,扶正固本。《本草纲目》:何首乌,白者入气分,赤者入血 分。肾主闭藏,肝主疏泄,此物气温味苦涩,苦补肾,温补肝,能收敛精气,所以能养血益肝, 固精益肾,健筋骨,乌发,为滋补良药,不寒不燥,功在地黄、天门冬诸药之上。气血太和,则 风虚、痈肿、瘰疬诸疾可知(除)矣。药理学研究表明:何首乌提取物对小鼠皮肤脂质过氧 化物的生成具有非常明显的抑制作用,说明何首乌具有延缓皮肤衰老的作用。肝肾不足,精 血亏虚,腰膝酸软,头晕耳鸣,须发早白,遗精滑精者,可与当归、枸杞子、菟丝子等配伍。
[0032] 本发明的方解是:方中枸杞子养肝滋肾,沙苑子温补肝肾,菟丝子、女贞子补肝肾、 益精髓,覆盆子补肾固精,补骨脂补肾助阳,以上六味共为君药,从身体的根本上进行养肝 滋肾,调理身体,补火助阳,安抚五脏。炙黄芪补气升阳,续断、杜仲补肝强肾,骨碎补、巴戟 天补肾助阳、强筋健骨,淫羊藿、仙茅补肾助阳、活血行血,以上七味共为臣药,一方面辅佐 君药补肾助阳,散寒止痛,另一方面对女性的身体进行活血调经,散寒止痛,调理经期血量, 促进女性身体雌性激素的生成,治疗患者病症。当归补血活血,熟地黄滋阴补血,炒山药补 脾养胃、补肾涩精,党参补益脾肺,红景天益智养心,黄精补气养阴,延胡索活血理气,丹参 活血调经、祛瘀止痛,茺蔚子活血调经,肉苁蓉补肾益精,制何首乌补血生精,以上几味共为 佐药,补脾和胃,是患者身体得到全部得到全面的调理,促进患者的恢复,是患者易于受孕, 另外使药物作用和缓,避免药物作用力过强对患者身体造成伤害。此方诸药合用,君臣协 力,佐使共辅,具有补肾助阳,活血调经,散寒止痛,调理身体的功效,能够有效治疗月经过 少致不孕。
[0033] 本发明药物原料用量是经发明人进行大量摸索总结得出的,各原料用量为在下述 重量份范围都具有较好的疗效:枸杞子15-25份、沙苑子15-25份、菟丝子15-25份、女贞 子13-23份、覆盆子10-20份、补骨脂10-20份、炙黄芪25-35份、续断15-25份、杜仲10-20 份、骨碎补13-23份、巴戟天7-17份、淫羊藿10-20份、仙茅7-17份、当归13-23份、熟地黄 13-23份、炒山药10-20份、党参10-20份、红景天13-23份、黄精15-25份、延胡索7-17份、 丹参13-23份、茺蔚子7-17份、肉苁蓉10-20份、制何首乌10-20份。
[0034] 其中优选为:枸杞子20份、沙苑子20份、菟丝子20份、女贞子18份、覆盆子15 份、补骨脂15份、炙黄芪30份、续断20份、杜仲15份、骨碎补18份、巴戟天12份、淫羊藿 15份、仙茅12份、当归18份、熟地黄18份、炒山药15份、党参15份、红景天18份、黄精20 份、延胡索12份、丹参18份、茺蔚子12份、肉苁蓉15份、制何首乌15份。
[0035] 本发明药物可以采用中药制剂的常规方法制备成任何常规内服制剂,如丸剂、散 齐U、片剂、口服液等。例如可以将这些原料药研成粉末混合均匀制成散剂冲服;可以用水煎, 经过滤得滤液,加入防腐剂制成口服液;必要时也可以直接服用汤剂。
[0036] 本发明优选的制备方法是汤剂,其制备方法如下: 步骤一:按本发明重量配比,先将枸杞子、沙苑子、菟丝子、女贞子、覆盆子、补骨脂、茺 蔚子用纱布包成药包,放于水中浸泡约45分钟,过滤,备用; 步骤二:按本发明重量配比,将炙黄芪、熟地黄、炒山药、制何首乌风干粉碎,研末至 180目筛,备用; 步骤三:按本发明重量配比,将续断、杜仲、骨碎补、巴戟天、仙茅、当归、党参、黄精、丹 参放入砂锅中,加步骤一中浸泡后剩余冷水,超过药面2〜5厘米,用武火煎沸后,再用文火 煎20〜30分钟,过滤,得滤液,在剩余药渣中加入3厘米左右的水,然后加入淫羊藿、延胡 索、肉苁蓉以及步骤一中的药包煎煮约30分钟,得滤液,合并两次滤液,过滤,弃渣,加入步 骤二中的粉末,混合均匀,既得本发明所述的中药汤剂,早晚各一次,温服。
[0037] 本发明药物具有补肾助阳,活血调经,散寒止痛,调理身体的功效,且疗效确切,副 作用小,服用方便,价格低廉,据对临床120例患者观察统计,使用本发明药物一个疗程总 有效率90%,两个疗程总有效率96. 7%。
具体实施方式
[0038] 实施例一、枸杞子15份、沙苑子15份、菟丝子15份、女贞子13份、覆盆子10份、补 骨脂10份、炎黄芪25份、续断15份、杜仲10份、骨碎补13份、巴戟天7份、淫羊藿10份、 仙茅7份、当归13份、熟地黄13份、炒山药10份、党参10份、红景天13份、黄精15份、延 胡索7份、丹参13份、茺蔚子7份、肉苁蓉10份、制何首乌10份。
[0039] 实施例二、枸杞子20份、沙苑子20份、菟丝子20份、女贞子18份、覆盆子15份、补 骨脂15份、炙黄芪30份、续断20份、杜仲15份、骨碎补18份、巴戟天12份、淫羊藿15份、 仙茅12份、当归18份、熟地黄18份、炒山药15份、党参15份、红景天18份、黄精20份、延 胡索12份、丹参18份、茺蔚子12份、肉苁蓉15份、制何首乌15份。
[0040] 实施例三、枸杞子25份、沙苑子25份、菟丝子25份、女贞子23份、覆盆子20份、补 骨脂20份、炎黄芪35份、续断25份、杜仲20份、骨碎补23份、巴戟天17份、淫羊藿20份、 仙茅17份、当归23份、熟地黄23份、炒山药20份、党参20份、红景天23份、黄精25份、延 胡索17份、丹参23份、茺蔚子17份、肉苁蓉20份、制何首乌20份。
[0041] 下面是患者使用本发明药物的临床统计资料: 一、一般资料 收治门诊患者120例,平均年龄34岁,病程时间不等。
[0042] 二、中医诊断标准 1、月经周期基本正常,经量很少,甚或点滴即净。
[0043] 2、育龄夫妇双方同居一年以上,有正常性生活,没有采用任何避孕措施的情况下, 未能成功怀孕。
[0044] 3、排除男方以及其他疾病因素。
[0045] 三、治疗方法 按照本发明药物重量配比,称取原料药(一日剂量),水煎后过滤去渣,早晚各服一次, 温服。30天为一个疗程。
[0046] 四、疗效评定标准: 1、治愈:经量恢复正常,维持3个月以上,医院检查子宫内膜适合孕育宝宝,并在调理 半年到一年左右顺利怀孕。
[0047] 2、好转:经量明显增多,医院检查子宫内膜逐渐恢复到自身最佳水平,身体状态逐 渐适合怀孕。
[0048] 3、无效:月经周期、经量无变化,其他体征无任何改变,或者是在两年后没有怀孕。
[0049] 五、治疗结果统计
Figure CN104352776AD00081
其中:总有效率=治愈率+好转率 通过治疗结果的统计表明,本发明中药在治疗月经过少致不孕方面具有良好的临床效 果,能有效提高治疗的治愈率,值得在临床应用上推广。
[0050] 典型病例及疗效: 病例一、患者马某,女,25岁,患者自述一直以来月经量少,以前一直没在意,结婚之后 一直没有怀上孩子,患者去医院查体,检查结果是长期月经量少引起子宫内膜增生不足,内 膜壁变薄,导致不易受孕,经朋友介绍,来我处就诊,采用本发明实施例二中所制制剂,以及 所选的制备方法,服用治疗两个个疗程后,患者经量明显增多,定期去医院查体,子宫内膜 逐渐恢复,继续服用两个疗程,患者去医院检查恢复情况,结果发现已经怀孕,欣喜不已,目 前状况良好,没有任何不适现象,痊愈。
[0051] 病例二、患者杨某,女,30岁,患者自述之前共做了两次药物流产,自从做完流产之 后,发现经血越来越少了,患者一直没有当回事,去年患者准备要宝宝,结果持续一年多没 能顺利的怀孕,去医院检查,因长期月经量少加上药流,引起子宫内膜壁非常薄,受孕比较 困难,患者希望采用中医保守治疗方法,希望能有一个健康的宝宝,来我处就诊,采用本发 明实施例二中所制制剂,以及所选的制备方法,服用治疗三个疗程后,患者经量逐渐增加到 之前正常的经量,去医院检查,子宫内膜厚度也有好转的现象,继续服用药物两个疗程后, 感觉有怀孕的症状,去医院检查,果然顺利怀上宝宝,各项检查均属正常,今年顺利产下一 个健康的宝宝,痊愈。

Claims (4)

1. 一种治疗月经过少致不孕的中药制剂,其特征在于,该中药制剂是由以下重量份的 药物制成:枸杞子15-25份、沙苑子15-25份、菟丝子15-25份、女贞子13-23份、覆盆子 10-20份、补骨脂10-20份、炙黄芪25-35份、续断15-25份、杜仲10-20份、骨碎补13-23 份、巴戟天7-17份、淫羊藿10-20份、仙茅7-17份、当归13-23份、熟地黄13-23份、炒山药 10-20份、党参10-20份、红景天13-23份、黄精15-25份、延胡索7-17份、丹参13-23份、茺 蔚子7-17份、肉苁蓉10-20份、制何首乌10-20份。
2. 根据权利要求1所述的治疗月经过少致不孕的中药制剂,其特征在于,由以下重量 份的药物制成:枸杞子20份、沙苑子20份、菟丝子20份、女贞子18份、覆盆子15份、补骨 脂15份、炎黄芪30份、续断20份、杜仲15份、骨碎补18份、巴戟天12份、淫羊藿15份、仙 茅12份、当归18份、熟地黄18份、炒山药15份、党参15份、红景天18份、黄精20份、延胡 索12份、丹参18份、茺蔚子12份、肉苁蓉15份、制何首乌15份。
3. 根据权利要求1或2所述的治疗月经过少致不孕的中药制剂,其特征在于:所述中 药制剂为汤剂。
4. 一种治疗月经过少致不孕的中药制剂的制备方法,其特征在于,制备方法如下:步 骤一:按本发明重量配比,先将枸杞子、沙苑子、菟丝子、女贞子、覆盆子、补骨脂、茺蔚子用 纱布包成药包,放于水中浸泡约45分钟,过滤,备用;步骤二:按本发明重量配比,将炙黄 芪、熟地黄、炒山药、制何首乌风干粉碎,研末至180目筛,备用;步骤三:按本发明重量配 t匕,将续断、杜仲、骨碎补、巴戟天、仙茅、当归、党参、黄精、丹参放入砂锅中,加步骤一中浸 泡后剩余冷水,超过药面2〜5厘米,用武火煎沸后,再用文火煎20〜30分钟,过滤,得滤 液,在剩余药渣中加入3厘米左右的水,然后加入淫羊藿、延胡索、肉苁蓉以及步骤一中的 药包煎煮约30分钟,得滤液,合并两次滤液,过滤,弃渣,加入步骤二中的粉末,混合均匀, 既得本发明所述的中药汤剂,早晚各一次,温服。
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CN106309564A (zh) * 2016-08-31 2017-01-11 田春燕 一种促进和改善女性生殖发育的中药组合物及其制备方法

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