CN107137530A - One kind is used for pet composition antianxity - Google Patents
One kind is used for pet composition antianxity Download PDFInfo
- Publication number
- CN107137530A CN107137530A CN201710566860.5A CN201710566860A CN107137530A CN 107137530 A CN107137530 A CN 107137530A CN 201710566860 A CN201710566860 A CN 201710566860A CN 107137530 A CN107137530 A CN 107137530A
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- mass parts
- composition
- pet
- extract
- tablet
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000203 mixture Substances 0.000 title claims abstract description 32
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims abstract description 20
- 229940038779 valerian root extract Drugs 0.000 claims abstract description 13
- 239000001192 valeriana officinalis l. rhizome/root Substances 0.000 claims abstract description 13
- OGNSCSPNOLGXSM-UHFFFAOYSA-N (+/-)-DABA Natural products NCCC(N)C(O)=O OGNSCSPNOLGXSM-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229960003692 gamma aminobutyric acid Drugs 0.000 claims abstract description 10
- 238000002360 preparation method Methods 0.000 claims abstract description 10
- 239000003826 tablet Substances 0.000 claims abstract description 9
- 239000000843 powder Substances 0.000 claims abstract description 5
- 239000008187 granular material Substances 0.000 claims abstract description 4
- 239000007938 effervescent tablet Substances 0.000 claims abstract description 3
- 239000007887 hard shell capsule Substances 0.000 claims abstract description 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims abstract description 3
- 239000000243 solution Substances 0.000 claims abstract description 3
- 235000007866 Chamaemelum nobile Nutrition 0.000 claims description 5
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 235000003599 food sweetener Nutrition 0.000 claims description 4
- 239000003765 sweetening agent Substances 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 244000126014 Valeriana officinalis Species 0.000 claims description 3
- 235000013832 Valeriana officinalis Nutrition 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 235000016788 valerian Nutrition 0.000 claims description 3
- 239000000853 adhesive Substances 0.000 claims description 2
- 230000001070 adhesive effect Effects 0.000 claims description 2
- KZNIFHPLKGYRTM-UHFFFAOYSA-N apigenin Chemical compound C1=CC(O)=CC=C1C1=CC(=O)C2=C(O)C=C(O)C=C2O1 KZNIFHPLKGYRTM-UHFFFAOYSA-N 0.000 claims description 2
- 229940117893 apigenin Drugs 0.000 claims description 2
- XADJWCRESPGUTB-UHFFFAOYSA-N apigenin Natural products C1=CC(O)=CC=C1C1=CC(=O)C2=CC(O)=C(O)C=C2O1 XADJWCRESPGUTB-UHFFFAOYSA-N 0.000 claims description 2
- 235000008714 apigenin Nutrition 0.000 claims description 2
- 239000007884 disintegrant Substances 0.000 claims description 2
- 239000000945 filler Substances 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 239000003755 preservative agent Substances 0.000 claims description 2
- 230000002335 preservative effect Effects 0.000 claims description 2
- 239000008213 purified water Substances 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims description 2
- 241000723353 Chrysanthemum Species 0.000 claims 2
- 235000007516 Chrysanthemum Nutrition 0.000 claims 2
- 235000009508 confectionery Nutrition 0.000 claims 2
- 240000003538 Chamaemelum nobile Species 0.000 claims 1
- 239000000470 constituent Substances 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 239000007919 dispersible tablet Substances 0.000 abstract description 3
- 244000042664 Matricaria chamomilla Species 0.000 description 4
- 230000000049 anti-anxiety effect Effects 0.000 description 3
- 239000002249 anxiolytic agent Substances 0.000 description 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical class [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 235000019359 magnesium stearate Nutrition 0.000 description 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 2
- 239000008108 microcrystalline cellulose Substances 0.000 description 2
- 229940016286 microcrystalline cellulose Drugs 0.000 description 2
- 230000036651 mood Effects 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 206010054196 Affect lability Diseases 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010026749 Mania Diseases 0.000 description 1
- 240000000111 Saccharum officinarum Species 0.000 description 1
- 235000007201 Saccharum officinarum Nutrition 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 230000002547 anomalous effect Effects 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229940100688 oral solution Drugs 0.000 description 1
- 239000007935 oral tablet Substances 0.000 description 1
- 229940096978 oral tablet Drugs 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011122 softwood Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 235000020985 whole grains Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/84—Valerianaceae (Valerian family), e.g. valerian
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to pet supplies product scope, it is related to a kind of for pet composition antianxity.Of the present invention to be used for pet composition antianxity, contained composition includes gamma aminobutyric acid, valerian root extract and camomile extract.A kind of composition calm for pet of the present invention can add common pharmaceutic adjuvant, it is prepared into hard shell capsules, tablet, granule, powder, solution, wherein described tablet includes conventional tablet, dispersible tablet and effervescent tablet, and preparation technology is simple and easy to do, with good industrial prospect.Present invention also offers the preparation technology of the composition product calm for pet.
Description
Technical field
The invention belongs to pet supplies areas, it is related to a kind of for pet composition antianxity.
Background technology
In fast pace, the modern society of high pressure, pet is raised into extensive hobby, is doted in many families
Thing is into critically important member.But, in face of certain situation such as thunder and lightning weather, move into the new home, entrust one's child to the care of sb. in others' family,
Remove hospital admission, by bus or when travelling on a plane etc., much usually show good pet and occur than large anomalous behavior, bag
Include repeatedly bark, grab sting furniture, run chaotically everywhere, the manic anxiety of mood etc., the trouble of keeper can be caused, and pet is in itself
Can be because the lasting appearance of emotional instability, the easily symptom such as insomnia, loss of appetite, jeopardizes the health of body.
Therefore, in these cases, its mood can be made gentle, normally with special antianxiety product to pet clothes
Feed and sleep, adapt to new environment faster.Current such product commercially more lacks, many families for raising pet
It is deep disturbed and at one's wit's end, therefore work well and pet easy to use with antianxiety product is to compare to be badly in need of and with good
Good prospect.
The content of the invention
It is used for pet composition antianxity it is an object of the invention to provide one kind, this product can antianxiety, pet of releiving
Intense strain effect is obvious, and preparation method is simple.
The present invention provides a kind of for pet composition antianxity, it is characterized in that the composition includes gamma-amino fourth
γ-aminobutyric acid, valerian root extract and chamomile are extracted in acid, valerian root extract and camomile extract, said composition
The mass ratio of thing is 1 ~ 3：5：5 ~ 10, preferably 1：5：5.
The present invention provide it is a kind of be used for pet composition antianxity, it is characterized in that valerian root extract refer to by radix valerianae by
The valerian root extract that recorded according to Chinese Pharmacopoeia or other extracting methods well known in the art are obtained, wherein valerian total acid content
0.8% must not be less than；Described camomile extract refers to recording chamomile according to Chinese Pharmacopoeia or other are well known in the art
The camomile extract that extracting method is obtained, wherein Quantitative Determination of Apigenin must not be less than 1.0%.
The present invention provides a kind of for pet composition antianxity, it is characterized in that the composition can add common
Pharmaceutic adjuvant, is prepared into hard shell capsules, tablet, granule, powder, solution, wherein the tablet includes conventional tablet, dispersible tablet
And effervescent tablet.
The present invention provides a kind of for pet composition antianxity, it is characterized in that the composition is prepared into solid pharmaceutical preparation
γ-aminobutyric acid, the valerian root extract of 5 mass parts and the chamomile of 5 ~ 10 mass parts of prescription including 1 ~ 3 mass parts carry
Take thing, the filler of 5 ~ 15 mass parts, the adhesive of 0 ~ 5 mass parts, the disintegrant of 0 ~ 10 mass parts, the lubrication of 0 ~ 5 mass parts
Agent and the sweetener of 0 ~ 1.5 mass parts.
The present invention provides a kind of for pet composition antianxity, it is characterized in that the composition is prepared into liquid preparation
γ-aminobutyric acid, the valerian root extract of 5 mass parts and the chamomile of 5 ~ 10 mass parts of prescription including 1 ~ 3 mass parts carry
Take thing, the acidity regulator of 1 ~ 10 mass parts, the sweetener of 0 ~ 5 mass parts, the preservative of 0 ~ 1.5 mass parts and appropriate purifying
Water.
Embodiment
The present invention is further elaborated by following examples, but the scope of the present invention is not limited to these embodiments.Institute
So that the simple modifications to the present invention under the premise of the method for the present invention belong to the scope of protection of present invention.
Embodiment 1
A kind of prescription that normal oral tablet is made for pet composition antianxity of the present invention：
Preparation technology：Supplementary material used is crossed to 100 mesh sieves respectively standby, weigh the γ-aminobutyric acid of recipe quantity, radix valerianae and extract
Thing and camomile extract and microcrystalline cellulose are well mixed, by the starch of recipe quantity, Ac-Di-Sol with it is above-mentioned
Powder is well mixed, and adds 4g magnesium stearates, is mixed, is pressed into 1000.
Embodiment 2
A kind of prescription that normal oral solution is made for pet composition antianxity of the present invention：
Preparation technology：The raw material of recipe quantity is weighed, is added in 60 DEG C of purified waters, stirring dissolves it.After after solution cooling
Other auxiliary materials are added, addition purified water is produced to full dose after filtering.
Embodiment 3
A kind of prescription that dispersible tablet is made for pet composition antianxity of the present invention：
Preparation technology：Supplementary material used is crossed to 100 mesh sieves respectively standby, weigh the γ-aminobutyric acid of recipe quantity, radix valerianae and extract
Thing and camomile extract and fine particle silica are well mixed, by the microcrystalline cellulose of recipe quantity, carboxyrnethyl starch sodium, trichlorine sugarcane
It is sugared to be well mixed with above-mentioned powder, 4g magnesium stearates are added, mixes, is pressed into 1000.
Embodiment 4
A kind of prescription that granule is made for pet composition antianxity of the present invention：
Preparation technology：By supplementary material used, 100 mesh sieves excessively are standby respectively, and the supplementary material for weighing recipe quantity is well mixed, with purifying
Suitable softwood is made in water, is pelletized with 18 eye mesh screens, is dried in less than 50 DEG C, dried particle 12 eye mesh screen whole grains, bag
Dress is produced.
Claims (5)
1. one kind is used for pet composition antianxity, it is characterized in that constituent includes γ-aminobutyric acid, valerian root extract
And camomile extract, the mass ratio of γ-aminobutyric acid, valerian root extract and camomile extract is 1 ~ 3 in said composition：
5：5 ~ 10, preferably 1：5：5.
2. one kind described in claim 1 is used for pet composition antianxity, it is characterized in that valerian root extract refers to valerian
The valerian root extract that root is recorded according to Chinese Pharmacopoeia or other extracting methods well known in the art are obtained, wherein valerian total acid
Content must not be less than 0.8%；It is public that described camomile extract refers to record chamomile according to Chinese Pharmacopoeia or other this areas
The camomile extract that the extracting method known is obtained, wherein Quantitative Determination of Apigenin must not be less than 1.0%.
3. one kind described in claim 1 is used for pet composition antianxity, it is characterized in that the composition can be added often
The pharmaceutic adjuvant seen, is prepared into hard shell capsules, tablet, granule, powder, solution, wherein the tablet includes conventional tablet, divided
Discrete piece and effervescent tablet.
4. one kind described in claim 1 is used for pet composition antianxity, it is characterized in that the composition is prepared into solid
The prescription of preparation includes the foreign sweet of γ-aminobutyric acid, the valerian root extract of 5 mass parts and 5 ~ 10 mass parts of 1 ~ 3 mass parts
Chrysanthemum extract, the filler of 5 ~ 15 mass parts, the adhesive of 0 ~ 5 mass parts, the disintegrant of 0 ~ 10 mass parts, 0 ~ 5 mass parts
The sweetener of lubricant and 0 ~ 1.5 mass parts.
5. one kind described in claim 1 is used for pet composition antianxity, it is characterized in that the composition is prepared into liquid
The prescription of preparation includes the foreign sweet of γ-aminobutyric acid, the valerian root extract of 5 mass parts and 5 ~ 10 mass parts of 1 ~ 3 mass parts
Chrysanthemum extract, the acidity regulator of 1 ~ 10 mass parts, the sweetener of 0 ~ 5 mass parts, the preservative of 0 ~ 1.5 mass parts and appropriate
Purified water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710566860.5A CN107137530A (en) | 2017-07-12 | 2017-07-12 | One kind is used for pet composition antianxity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710566860.5A CN107137530A (en) | 2017-07-12 | 2017-07-12 | One kind is used for pet composition antianxity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107137530A true CN107137530A (en) | 2017-09-08 |
Family
ID=59776375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710566860.5A Pending CN107137530A (en) | 2017-07-12 | 2017-07-12 | One kind is used for pet composition antianxity |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107137530A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108338277A (en) * | 2018-01-31 | 2018-07-31 | 上海普缇康生物技术有限公司 | A kind of pet stomach is good for the preparation method of additive for microbe feedstuff |
| CN115282101A (en) * | 2022-06-30 | 2022-11-04 | 媞颂日化用品(广州)有限公司 | Pet bath lotion capable of reducing stress response of cats and preparation method of pet bath lotion |
-
2017
- 2017-07-12 CN CN201710566860.5A patent/CN107137530A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108338277A (en) * | 2018-01-31 | 2018-07-31 | 上海普缇康生物技术有限公司 | A kind of pet stomach is good for the preparation method of additive for microbe feedstuff |
| CN115282101A (en) * | 2022-06-30 | 2022-11-04 | 媞颂日化用品(广州)有限公司 | Pet bath lotion capable of reducing stress response of cats and preparation method of pet bath lotion |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170908 |
|
| WD01 | Invention patent application deemed withdrawn after publication |