CN107125533A - A kind of preparation method of Xuancheng's pawpaw effervescent tablet - Google Patents

A kind of preparation method of Xuancheng's pawpaw effervescent tablet Download PDF

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Publication number
CN107125533A
CN107125533A CN201710434264.1A CN201710434264A CN107125533A CN 107125533 A CN107125533 A CN 107125533A CN 201710434264 A CN201710434264 A CN 201710434264A CN 107125533 A CN107125533 A CN 107125533A
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xuancheng
pawpaw
effervescent tablet
extract
preparation
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CN201710434264.1A
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Chinese (zh)
Inventor
商亚芳
马意龙
张博亚
冯国栋
张雨涵
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Hefei University of Technology
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Hefei University of Technology
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Priority to CN201710434264.1A priority Critical patent/CN107125533A/en
Publication of CN107125533A publication Critical patent/CN107125533A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/40Effervescence-generating compositions
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • A23L2/60Sweeteners
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a kind of preparation method of Xuancheng's pawpaw effervescent tablet.Operating procedure is as follows:In mass ratio by Xuancheng's pawpaw extract medicinal extract and beta cyclodextrin, add distilled water and be well mixed, Xuancheng's pawpaw extract powder is obtained after vacuum freeze drying;Xuancheng's pawpaw extract powder is mixed with sodium acid carbonate, sweetener etc. by a certain percentage, tabletting produces Xuancheng's pawpaw effervescent tablet.The characteristics of present invention is using Xuancheng's pawpaw fruit chemical composition organic acid and abundant polyoses content, reduces the use of additive in effervescent tablet, and the security and acceptable degree of effervescent tablet are improved while reducing production cost.

Description

A kind of preparation method of Xuancheng's pawpaw effervescent tablet
Technical field
The present invention relates to field of food, the few effervescent tablet of more particularly to a kind of additive level.
Background technology
Xuancheng's pawpaw, is the peculiar Chaenomeles Cultivars of Xuancheng City of Anhui Province, is the food and medicament dual-purpose Chinese medicine for having higher-value, with tribute Chrysanthemum, Bo Chinese herbaceous peony, root bark of tree peony nominal are the big authentic medicinal herbs in Anhui four, the title for having " hundred benefits fruit ".Xuancheng's pawpaw is because containing having compared with horn of plenty Machine acid, tannin, make its sour-puckery flavor and are used for medicinal purpose more.However, Xuancheng's pawpaw extract is by appropriate regulation, can be by sour and astringent mouth Sensing control system is in the acceptable scope of consumer.The polysaccharide and organic acid isoreactivity composition enriched in Xuancheng's pawpaw extract, is adapted to The exploitation of effervescent tablet.At present, the effervescent tablet of in the market circulation is containing lubricant, adhesive, effervescent agent acid source and alkali source, sweet taste The substantial amounts of food additives such as agent.Therefore, easily there are security concerns in consumer before purchase.
The content of the invention
The present invention combines the characteristics of Xuancheng's pawpaw organic acid, polysaccharide isoreactivity component content are abundant, and food is carried out to Xuancheng's pawpaw Exploitation, the use of food additive in manufacturing process is reduced using Xuancheng's pawpaw active component feature.The present invention provide it is a kind of with Xuancheng's pawpaw is the preparation method of the effervescent tablet of main body.
The operating procedure of effervescent tablet of the preparation based on Xuancheng's pawpaw is as follows:
(1)Take Xuancheng's pawpaw extract medicinal extract and beta-schardinger dextrin in mass ratio 1:0.5-1:11, it is mixed with water;Vacuum refrigeration is done It is dry, pulverize, obtain Xuancheng's pawpaw extract powder;Xuancheng's pawpaw extract medicinal extract is what Xuancheng's pawpaw was obtained through 70% alcohol steep Xuancheng's pawpaw extract medicinal extract, pH value is 2.0~2.7, includes organic acid, polysaccharide, polyphenol active component;
(2)By Xuancheng's pawpaw extract powder and sodium acid carbonate in mass ratio 1:0.2-1:1.2 ground and mixeds are uniform, obtain effervesce Agent;
(3)Sweetener was pulverized 80 mesh sieves, by effervescent agent and sweetener in mass ratio by 1:0.5-1:1.5 mixing are equal Even, Xuancheng's pawpaw effervescent tablet is made in tabletting;The Xuancheng's pawpaw effervescent tablet content is only containing Xuancheng's pawpaw extract medicinal extract, β-ring paste Essence, sweetener and sodium acid carbonate.
The monolithic quality of the Xuancheng's pawpaw effervescent tablet is 0.2 g, and polyphenol content is equivalent to catechin 3.81-22.9 mg, profit The antioxidation activity of effervescent tablet is surveyed with ABTS methods, when free radical scavenging activity is 50%, the polyphenoils phase that inside is contained Added when in Vc 0.13-0.75 mg, not containing the food such as adhesive, effervescent agent acid source and lubricant compared with other effervescent tablets Agent.
The technical scheme further limited is as follows:
Step(1)In, take Xuancheng's pawpaw extract medicinal extract and beta-schardinger dextrin in mass ratio 1:0.5-1:11, it is mixed with water, obtains To Xuancheng's pawpaw extract powder.
Step(1)In, Xuancheng's pawpaw extract powder crosses 80 mesh sieves.
Step(2)In, by Xuancheng's pawpaw extract powder and sodium acid carbonate in mass ratio 1:0.2-1:1.2 ground and mixeds are equal It is even, obtain effervescent agent.
Step(2)In, by ground 80 mesh sieve of sodium acid carbonate.
Step(3)In, the sweetener is sucrose or white granulated sugar or xylan or xylitol.
Step(3)In, it is 1 in mass ratio by effervescent agent and sweetener:0.5-1:1.5.
The advantageous effects of the present invention embody in the following areas:
1. make papaya extractives that there is good moisture-absorption characteristics and larger viscosity rich in there is abundant polysaccharide in Xuancheng's pawpaw.Cause This, step of the present invention(1)Middle use beta-schardinger dextrin is prepared after being mixed with Xuancheng's pawpaw extract, can effectively be reduced pawpaw and be carried The moisture-absorption characteristics of thing is taken, Xuancheng's pawpaw is kept pulverulence, it is prevented from caking and dry rapid, while also retains appropriate suction Wet, adhesive power, makes effervescent tablet to complete nothing in tableting processes, and tableting processes without addition adhesive and lubricant in addition Sticking phenomenon, tabletting shows that smooth and hardness is good, and the disintegration time of tabletting meets national standard.
2. step of the present invention(2)Rich in abundant organic acid, including citric acid, malic acid, winestone in middle utilization Xuancheng's pawpaw The active ingredient such as acid and ascorbic acid, acidity reaches as high as pH 2.5 or so.Using this characteristic, effervescent agent acid source can be removed from Addition, only add effervescent agent alkali source can complete the making of effervescent agent, reduce the addition of additive acid source.
3. the obtained effervescent tablet monolithic quality of the present invention is 0.2 g, polyphenol content is equivalent to catechin 3.81-22.90 Mg, the antioxidation activity of effervescent tablet is surveyed using ABTS methods, when free radical scavenging activity is 50%, the polyphenoils that inside is contained Matter is equivalent to Vc 0.13-0.75 mg.Effervescent tablet made from the inventive method compared with other effervescent tablets, do not contain lubricant, Adhesive, it is not necessary to use effervescent agent acid source.The reduction of additive, improves foodsafety, while reducing food production The production cost of enterprise.
Embodiment
With reference to embodiment, the present invention is further described.
Embodiment 1
(1)Take 10 g Xuancheng's pawpaw extract medicinal extract and 20 g beta-schardinger dextrins(The mass ratio of the two is 1:2), add 300 mL and steam Distilled water is well mixed;- 20 DEG C of h of pre-freeze 12, are less than 100 Pa in vacuum, and condenser temperature is less than under the conditions of -50 DEG C, and vacuum is cold Freeze dry 36 h;Pulverized 80 mesh sieves, and obtained Xuancheng's pawpaw extract powder;
(2)By ground 80 mesh sieve of sodium acid carbonate, take 12 g sodium acid carbonates and 10 g Xuancheng's pawpaws extract powders well mixed(Two The mass ratio 1 of person:0.8), effervescent agent is made;
(3)80 mesh sieves are crossed after sucrose is ground, 12.5 g sucrose are added in 10 g effervescent agents and are well mixed(The mass ratio of the two For 1:1.25), tabletting produces Xuancheng's pawpaw effervescent tablet.The quality of monolithic be 0.2g, through Forint phenol method determine total phenol content equivalent to The mg of catechin 22.9, when to ABTS free radical scavenging activities are 50% when, the polyphenoils that contains of inside is equivalent to Vc 0.75 mg。
Embodiment 2
(1)Take 10 g Xuancheng's pawpaw extract medicinal extract and 20 g beta-schardinger dextrins(The mass ratio of the two is 1:2), add 300 mL and steam Distilled water is well mixed;- 20 DEG C of h of pre-freeze 12, are less than 100 Pa in vacuum, and condenser temperature is less than under the conditions of -50 DEG C, and vacuum is cold Freeze dry 36 h;Pulverized 80 mesh sieves, and obtained Xuancheng's pawpaw extract powder;
(2)By ground 80 mesh sieve of sodium acid carbonate, take 25 g sodium acid carbonates and 10 g Xuancheng's pawpaws extract powders well mixed(Two The mass ratio 1 of person:0.4), effervescent agent is made;
(3)80 mesh sieves are crossed after glucan is ground, 5 g glucans are added in 10 g effervescent agents and are well mixed(The quality of the two Than for 1:0.5), tabletting produces Xuancheng's pawpaw effervescent tablet.
The quality of monolithic is 0.2 g, total phenol content is determined equivalent to the mg of catechin 15.26 through Forint phenol method, when to ABTS When free radical scavenging activity is 50%, the polyphenoils that inside is contained is equivalent to the mg of Vc 0.5.
Embodiment 3
(1)Taking 10 g Xuancheng's pawpaw extract medicinal extract and 20 g beta-schardinger dextrins, (mass ratio of the two is 1:2), 300 mL are added to steam Distilled water is well mixed;- 20 DEG C of h of pre-freeze 12, are less than 100 Pa in vacuum, and condenser temperature is less than under the conditions of -50 DEG C, and vacuum is cold Freeze dry 36 h;Pulverized 80 mesh sieves, and obtained Xuancheng's pawpaw extract powder;
(2)By ground 80 mesh sieve of sodium acid carbonate, take 16.6 g and 10 g Xuancheng's pawpaws extract powders well mixed(The two Mass ratio is 1:0.6), effervescent agent is made;
(3)80 mesh sieves are crossed after white granulated sugar is ground, 7.5g white granulated sugars are added in 10 g effervescent agents and are well mixed(The quality of the two Than for 1:0.75), tabletting produces Xuancheng's pawpaw effervescent tablet.
The quality of monolithic is 0.2 g, total phenol content is determined equivalent to the mg of catechin 10.94 through Forint phenol method, when right When ABTS free radical scavenging activities are 50%, the polyphenoils that inside is contained is equivalent to the mg of Vc 0.35.
Embodiment 4
(1)Take 10 g Xuancheng's pawpaw extract medicinal extract and 20 g beta-schardinger dextrin(The mass ratio of the two is 1:2), add 300 mL and steam Distilled water is well mixed;- 20 DEG C of h of pre-freeze 12, are less than 100 Pa in vacuum, and condenser temperature is less than under the conditions of -50 DEG C, and vacuum is cold Freeze dry 36 h;Pulverized 80 mesh sieves, and obtained Xuancheng's pawpaw extract powder;
(2)By ground 80 mesh sieve of sodium acid carbonate, take 10 g and 10 g Xuancheng's pawpaws extract powders well mixed(The quality of the two Than for 1:1), effervescent agent is made;
(3)80 mesh sieves are crossed after xylitol is ground, 12.5 g xylitols are added in 10 g effervescent agents and are well mixed(The matter of the two Amount is than being 1:1.25)Tabletting, produces Xuancheng's pawpaw effervescent tablet.
The quality of monolithic is 0.2 g, total phenol content is determined equivalent to the mg of catechin 22.6 through Forint phenol method, when to ABTS When free radical scavenging activity is 50%, the polyphenoils that inside is contained is equivalent to the mg of Vc 0.70.
Embodiment 5
(1)Take 10 g Xuancheng's pawpaw extract medicinal extract and 110 g beta-schardinger dextrins(The mass ratio of the two is 1:11), add 1000 mL Distilled water is well mixed;- 20 DEG C of h of pre-freeze 12, are less than 100 Pa in vacuum, and condenser temperature is less than under the conditions of -50 DEG C, vacuum It is freeze-dried 36 h;Pulverized 80 mesh sieves, and obtained Xuancheng's pawpaw extract powder;
(2)By ground 80 mesh sieve of sodium acid carbonate, take 12 g with and 10 g Xuancheng's pawpaw extract powders be well mixed(The matter of the two Amount is than being 1:0.8), effervescent agent is made;
(3)80 mesh sieves are crossed after sucrose is ground, 15 g sucrose are added in 10 g effervescent agents and are well mixed(The mass ratio of the two is 1:1.5), tabletting produces Xuancheng's pawpaw effervescent tablet.
The quality of monolithic is 0.2 g, total phenol content is determined equivalent to the mg of catechin 3.81 through Forint phenol method, when to ABTS When free radical scavenging activity is 50%, the polyphenoils that inside is contained is equivalent to the mg of Vc 0.13.

Claims (7)

1. a kind of preparation method of Xuancheng's pawpaw effervescent tablet, it is characterised in that operating procedure is as follows:
(1)Take Xuancheng's pawpaw extract medicinal extract and beta-schardinger dextrin in mass ratio 1:0.5-1:20, it is mixed with water;Vacuum refrigeration is done It is dry, pulverize, obtain Xuancheng's pawpaw extract powder;Xuancheng's pawpaw extract medicinal extract is what Xuancheng's pawpaw was obtained through 70% alcohol steep Xuancheng's pawpaw extract medicinal extract, pH value is 2.0~2.7, includes organic acid, polysaccharide, polyphenol active component;
(2)By Xuancheng's pawpaw extract powder and sodium acid carbonate in mass ratio 1:0.1-1:1.5 ground and mixeds are uniform, obtain effervesce Agent;
(3)Sweetener is pulverized, by effervescent agent and sweetener in mass ratio by 1:0.2-1:2.0 are well mixed, tabletting, system Obtain Xuancheng's pawpaw effervescent tablet;The Xuancheng's pawpaw effervescent tablet content only containing Xuancheng's pawpaw extract medicinal extract, beta-schardinger dextrin, sweetener and Sodium acid carbonate;
The monolithic quality of the Xuancheng's pawpaw effervescent tablet is 0.2 g, and polyphenol content is utilized equivalent to catechin 3.81-22.9 mg ABTS methods survey the antioxidation activity of effervescent tablet, and when free radical scavenging activity is 50%, the polyphenoils that inside is contained is suitable In Vc 0.13-0.75 mg.
2. a kind of preparation method of Xuancheng's pawpaw effervescent tablet according to claim 1, it is characterised in that:Step(1)In, take a surname Papaya extractives medicinal extract and beta-schardinger dextrin in mass ratio 1:0.5-1:11, it is mixed with water.
3. a kind of preparation method of Xuancheng's pawpaw effervescent tablet according to claim 1, it is characterised in that:Step(2)In, it will declare Papaya extractives pulvis and sodium acid carbonate in mass ratio 1:0.2-1:1.2 ground and mixeds are uniform, obtain effervescent agent.
4. a kind of preparation method of Xuancheng's pawpaw effervescent tablet according to claim 1, it is characterised in that:Step(2)In, effervesce 80 mesh sieves are crossed in agent.
5. a kind of preparation method of Xuancheng's pawpaw effervescent tablet according to claim 1, it is characterised in that:Step(2)In, by carbon Sour ground 80 mesh sieve of hydrogen sodium.
6. a kind of preparation method of Xuancheng's pawpaw effervescent tablet according to claim 1, it is characterised in that:Step(3)In, it is described Sweetener is sucrose or white granulated sugar or xylan or xylitol.
7. a kind of preparation method of Xuancheng's pawpaw effervescent tablet according to claim 1, it is characterised in that:Step(3)In, it will steep It is 1 in mass ratio with sweetener to rise agent:0.5-1:1.5.
CN201710434264.1A 2017-06-09 2017-06-09 A kind of preparation method of Xuancheng's pawpaw effervescent tablet Pending CN107125533A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108902929A (en) * 2018-08-22 2018-11-30 合肥工业大学 Xuancheng's pawpaw lucidum spore powder tablet and its preparation method and application
CN112056531A (en) * 2020-09-21 2020-12-11 广东食品药品职业学院 Aloe, pawpaw and honey effervescent granule and preparation method thereof

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CN101028321A (en) * 2006-09-27 2007-09-05 张干元 Zizhuiju effervescent tablets and preparing process thereof
CN101401798A (en) * 2008-11-14 2009-04-08 江苏大学 Proanthocyanidin effervescent tablet and preparation method thereof
CN101612221A (en) * 2009-07-31 2009-12-30 中国人民解放军第三军医大学 Pawpaw nutritional effervescence tablet and preparation method thereof
CN101711811A (en) * 2009-08-14 2010-05-26 曹芬 Method for preparing Chaenomeles speciosa Nakai buccal tablet
CN102229638A (en) * 2011-04-26 2011-11-02 安徽农业大学 Method for extracting oleanolic acid from chaenomeles fruit and preparing oleanolic acid standard
CN102423045A (en) * 2011-12-15 2012-04-25 宁蒗女儿珍生物工程有限公司 Preparation method of wrinkled papaya buccal tablets
CN103584012A (en) * 2013-11-15 2014-02-19 河南农业大学 Production process of chaenomeles speciosa slices
CN104824783A (en) * 2015-03-24 2015-08-12 辽宁双增生物工程有限公司 A preparing method of a sea cucumber protein effervescent tablet
CN106177020A (en) * 2016-08-19 2016-12-07 中南民族大学 The extraction of total phenolics and purifying process in a kind of wrinkled papaya

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101028321A (en) * 2006-09-27 2007-09-05 张干元 Zizhuiju effervescent tablets and preparing process thereof
CN101401798A (en) * 2008-11-14 2009-04-08 江苏大学 Proanthocyanidin effervescent tablet and preparation method thereof
CN101612221A (en) * 2009-07-31 2009-12-30 中国人民解放军第三军医大学 Pawpaw nutritional effervescence tablet and preparation method thereof
CN101711811A (en) * 2009-08-14 2010-05-26 曹芬 Method for preparing Chaenomeles speciosa Nakai buccal tablet
CN102229638A (en) * 2011-04-26 2011-11-02 安徽农业大学 Method for extracting oleanolic acid from chaenomeles fruit and preparing oleanolic acid standard
CN102423045A (en) * 2011-12-15 2012-04-25 宁蒗女儿珍生物工程有限公司 Preparation method of wrinkled papaya buccal tablets
CN103584012A (en) * 2013-11-15 2014-02-19 河南农业大学 Production process of chaenomeles speciosa slices
CN104824783A (en) * 2015-03-24 2015-08-12 辽宁双增生物工程有限公司 A preparing method of a sea cucumber protein effervescent tablet
CN106177020A (en) * 2016-08-19 2016-12-07 中南民族大学 The extraction of total phenolics and purifying process in a kind of wrinkled papaya

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108902929A (en) * 2018-08-22 2018-11-30 合肥工业大学 Xuancheng's pawpaw lucidum spore powder tablet and its preparation method and application
CN112056531A (en) * 2020-09-21 2020-12-11 广东食品药品职业学院 Aloe, pawpaw and honey effervescent granule and preparation method thereof

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Application publication date: 20170905