CN107109403A - 在噬菌体颗粒上展示环肽的新方法 - Google Patents
在噬菌体颗粒上展示环肽的新方法 Download PDFInfo
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
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Landscapes
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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| EP14199588 | 2014-12-22 | ||
| EP14199588.6 | 2014-12-22 | ||
| PCT/EP2015/080738 WO2016102434A1 (en) | 2014-12-22 | 2015-12-21 | Novel methods for displaying cyclic peptides on bacteriophage particles |
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| CN107109403A true CN107109403A (zh) | 2017-08-29 |
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| JP (1) | JP6810041B2 (enExample) |
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| WO (1) | WO2016102434A1 (enExample) |
| ZA (1) | ZA201704674B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109432399A (zh) * | 2018-12-27 | 2019-03-08 | 重庆市科学技术研究院 | 用于乙型肝炎的环肽药物及其应用 |
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| WO2012019928A1 (en) | 2010-08-13 | 2012-02-16 | Guntram Christiansen | Modified peptide display |
| CN106366168B (zh) * | 2016-08-26 | 2020-09-15 | 上海交通大学 | 羊毛硫肽类抗菌肽及其脱氢衍生物的制备方法 |
| CN113727725A (zh) * | 2019-05-20 | 2021-11-30 | 得克萨斯A&M大学系统 | 遗传编码的噬菌体展示的环状肽文库及其制备方法 |
| US20230304025A1 (en) * | 2020-07-20 | 2023-09-28 | Massachusetts Institute Of Technology | M13 bacteriophage with a high cysteine content and genetically engineerable hydrogels |
| CN112851788B (zh) * | 2021-02-03 | 2022-11-01 | 河北省科学院生物研究所 | 一种羊毛硫肽LichencinA3及其制备方法和应用 |
| PL443378A1 (pl) * | 2022-12-31 | 2024-07-01 | Instytut Biotechnologii I Medycyny Molekularnej | 7 aminokwasowe sekwencje oraz klony fagowe wiążące selektywnie jony niklu |
| CN116790698B (zh) * | 2023-06-21 | 2024-06-18 | 南京大学 | 基于氧化脱羧酶的硫醛合成方法及其应用 |
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| KR20170090509A (ko) | 2017-08-07 |
| RU2017122176A (ru) | 2019-01-24 |
| EP3237614B1 (en) | 2019-06-26 |
| EP3237614A1 (en) | 2017-11-01 |
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| AU2015371172A1 (en) | 2017-07-13 |
| CA2971672A1 (en) | 2016-06-30 |
| RU2017122176A3 (enExample) | 2019-04-03 |
| ZA201704674B (en) | 2019-09-25 |
| US20180051276A1 (en) | 2018-02-22 |
| JP2018500352A (ja) | 2018-01-11 |
| JP6810041B2 (ja) | 2021-01-06 |
| RU2702087C2 (ru) | 2019-10-03 |
| MX2017008286A (es) | 2018-02-19 |
| US20200385705A1 (en) | 2020-12-10 |
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