MX2017008286A - Nuevos metodos para el despliegue de peptidos ciclicos en particulas de bacteriofagos. - Google Patents

Nuevos metodos para el despliegue de peptidos ciclicos en particulas de bacteriofagos.

Info

Publication number
MX2017008286A
MX2017008286A MX2017008286A MX2017008286A MX2017008286A MX 2017008286 A MX2017008286 A MX 2017008286A MX 2017008286 A MX2017008286 A MX 2017008286A MX 2017008286 A MX2017008286 A MX 2017008286A MX 2017008286 A MX2017008286 A MX 2017008286A
Authority
MX
Mexico
Prior art keywords
cyclic peptides
novel methods
bacteriophage particles
displaying cyclic
displaying
Prior art date
Application number
MX2017008286A
Other languages
English (en)
Inventor
Prassler Josef
Andreas Moosmeier Markus
Bosma Tjibbe
Herbert URBAN Johannes
Original Assignee
Morphosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag filed Critical Morphosys Ag
Publication of MX2017008286A publication Critical patent/MX2017008286A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/00021—Viruses as such, e.g. new isolates, mutants or their genomic sequences

Abstract

La presente invención se refiere a métodos para presentación de péptidos cíclicos en la superficie de partículas de bacteriófago y colecciones de los mismos.
MX2017008286A 2014-12-22 2015-12-21 Nuevos metodos para el despliegue de peptidos ciclicos en particulas de bacteriofagos. MX2017008286A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14199588 2014-12-22
PCT/EP2015/080738 WO2016102434A1 (en) 2014-12-22 2015-12-21 Novel methods for displaying cyclic peptides on bacteriophage particles

Publications (1)

Publication Number Publication Date
MX2017008286A true MX2017008286A (es) 2018-02-19

Family

ID=52292661

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017008286A MX2017008286A (es) 2014-12-22 2015-12-21 Nuevos metodos para el despliegue de peptidos ciclicos en particulas de bacteriofagos.

Country Status (12)

Country Link
US (2) US10774323B2 (es)
EP (1) EP3237614B1 (es)
JP (1) JP6810041B2 (es)
KR (1) KR20170090509A (es)
CN (1) CN107109403A (es)
AU (1) AU2015371172B2 (es)
CA (1) CA2971672A1 (es)
DK (1) DK3237614T3 (es)
MX (1) MX2017008286A (es)
RU (1) RU2702087C2 (es)
WO (1) WO2016102434A1 (es)
ZA (1) ZA201704674B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106366168B (zh) * 2016-08-26 2020-09-15 上海交通大学 羊毛硫肽类抗菌肽及其脱氢衍生物的制备方法
CN109432399A (zh) * 2018-12-27 2019-03-08 重庆市科学技术研究院 用于乙型肝炎的环肽药物及其应用
EP3972625A4 (en) * 2019-05-20 2023-04-12 The Texas A&M University System GENETICALLY ENCODED PHAGE DISPLAYED CYCLIC PEPTIDE LIBRARY AND METHODS OF PRODUCTION THEREOF
WO2022020380A1 (en) * 2020-07-20 2022-01-27 Massachusetts Institute Of Technology M13 bacteriophage with a high cysteine content and genetically engineerable hydrogels
CN112851788B (zh) * 2021-02-03 2022-11-01 河北省科学院生物研究所 一种羊毛硫肽LichencinA3及其制备方法和应用
CN116790698A (zh) * 2023-06-21 2023-09-22 南京大学 基于氧化脱羧酶的硫醛合成方法及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3852304T3 (de) 1987-03-02 1999-07-01 Enzon Lab Inc Organismus als Träger für "Single Chain Antibody Domain (SCAD)".
DE768377T1 (de) 1988-09-02 1998-01-02 Dyax Corp Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen
US6660843B1 (en) * 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
CA2376232A1 (en) 1999-06-14 2000-12-21 Genentech, Inc. A structured peptide scaffold for displaying turn libraries on phage
WO2006062398A2 (en) 2004-12-07 2006-06-15 Applied Nanosystems B.V. Methods for the production and secretion of modified peptides
JP2009511053A (ja) * 2005-10-12 2009-03-19 ザ スクリップス リサーチ インスティテュート ファージ提示型ポリペプチドの選択的翻訳後修飾
ATE555200T1 (de) 2008-02-05 2012-05-15 Medical Res Council Verfahren und zusammensetzungen
EP2405008A1 (en) 2010-07-06 2012-01-11 LanthioPep B.V. Bacterial surface display of thioether-bridge-containing peptides
WO2012019928A1 (en) * 2010-08-13 2012-02-16 Guntram Christiansen Modified peptide display
EP2578599A1 (en) 2011-10-07 2013-04-10 LanthioPep B.V. Cyclic analogs of GLP-1 and GLP-1 related peptides
WO2016049656A1 (en) * 2014-09-26 2016-03-31 The Board Of Trustees Of The University Of Illinois Biosynthesis and engineering of lanthipeptides

Also Published As

Publication number Publication date
CN107109403A (zh) 2017-08-29
JP6810041B2 (ja) 2021-01-06
CA2971672A1 (en) 2016-06-30
JP2018500352A (ja) 2018-01-11
RU2017122176A (ru) 2019-01-24
DK3237614T3 (da) 2019-09-09
EP3237614B1 (en) 2019-06-26
US10774323B2 (en) 2020-09-15
RU2017122176A3 (es) 2019-04-03
ZA201704674B (en) 2019-09-25
US20200385705A1 (en) 2020-12-10
AU2015371172B2 (en) 2021-05-13
RU2702087C2 (ru) 2019-10-03
EP3237614A1 (en) 2017-11-01
US20180051276A1 (en) 2018-02-22
AU2015371172A1 (en) 2017-07-13
KR20170090509A (ko) 2017-08-07
WO2016102434A1 (en) 2016-06-30

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