CN107073021A - 合成组合物以及用于治疗肠易激综合症的方法 - Google Patents

合成组合物以及用于治疗肠易激综合症的方法 Download PDF

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Publication number
CN107073021A
CN107073021A CN201580058523.4A CN201580058523A CN107073021A CN 107073021 A CN107073021 A CN 107073021A CN 201580058523 A CN201580058523 A CN 201580058523A CN 107073021 A CN107073021 A CN 107073021A
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ibs
patient
patients
hmo
impaired
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CN201580058523.4A
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Chinese (zh)
Inventor
T·亨内特
B·麦康奈尔
E·萨洛蒙松
L·K·比格斯奈斯
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Glycom AS
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Glycom AS
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Priority to CN202211004557.3A priority Critical patent/CN115364113A/zh
Publication of CN107073021A publication Critical patent/CN107073021A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A23C9/206—Colostrum; Human milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201580058523.4A 2014-10-29 2015-10-29 合成组合物以及用于治疗肠易激综合症的方法 Pending CN107073021A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202211004557.3A CN115364113A (zh) 2014-10-29 2015-10-29 合成组合物以及用于治疗肠易激综合症的方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201470663 2014-10-29
DKPA201470663 2014-10-29
PCT/DK2015/050332 WO2016066175A1 (en) 2014-10-29 2015-10-29 Synthetic composition and method for treating irritable bowel syndrome

Related Child Applications (1)

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CN202211004557.3A Division CN115364113A (zh) 2014-10-29 2015-10-29 合成组合物以及用于治疗肠易激综合症的方法

Publications (1)

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CN107073021A true CN107073021A (zh) 2017-08-18

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CN201580058523.4A Pending CN107073021A (zh) 2014-10-29 2015-10-29 合成组合物以及用于治疗肠易激综合症的方法
CN202211004557.3A Pending CN115364113A (zh) 2014-10-29 2015-10-29 合成组合物以及用于治疗肠易激综合症的方法

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US (3) US20160346303A1 (https=)
EP (1) EP3212197A4 (https=)
JP (2) JP7182872B2 (https=)
CN (2) CN107073021A (https=)
WO (1) WO2016066175A1 (https=)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111432661A (zh) * 2017-12-22 2020-07-17 雀巢产品有限公司 用途是用于减少婴儿和幼儿的伤害感觉的组合物
CN111526879A (zh) * 2017-11-02 2020-08-11 格礼卡姆股份公司 用于减少或预防疲劳和/或改善注意力或专注力的一种或多种hmo
CN111683666A (zh) * 2017-12-22 2020-09-18 格礼卡姆股份公司 预防或减少伤害感受的包含hmo的组合物
CN113194960A (zh) * 2018-12-19 2021-07-30 格礼卡姆股份公司 用于治疗使用低fodmap饮食的人的组合物和方法
CN113939340A (zh) * 2019-06-12 2022-01-14 格礼卡姆股份公司 用于预防、管理或治疗偏头痛相关症状的人乳寡糖及其组合物
CN114401642A (zh) * 2019-09-18 2022-04-26 科汉森母乳低聚糖股份有限公司 含有人乳寡糖的谷物组合物
CN114728015A (zh) * 2019-11-14 2022-07-08 格礼卡姆股份公司 用于平衡肠中胆汁酸谱的合成组合物
CN116528695A (zh) * 2020-12-04 2023-08-01 格礼卡姆股份公司 用于支持睡眠模式的成熟或改善的人乳寡糖
CN120570904A (zh) * 2025-07-14 2025-09-02 苏州一兮生物技术有限公司 一种用于预防和/或治疗腹泻的组合物及其用途

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3209673T5 (pl) * 2014-10-24 2023-10-23 Glycom A/S Mieszaniny hmo
US11040049B2 (en) * 2014-10-29 2021-06-22 Glycom A/S Composition comprising HMSs/HMOs and use thereof
WO2021111422A1 (en) * 2019-12-06 2021-06-10 Glycom A/S Composition comprising 2'-fl and dfl for use in a method for reducing pain
EP3212197A4 (en) 2014-10-29 2018-07-11 Glycom A/S Synthetic composition and method for treating irritable bowel syndrome
US11040050B2 (en) 2014-10-29 2021-06-22 Glycom A/S Composition comprising HMSs/HMOs and use thereof
CN107846957A (zh) * 2015-03-05 2018-03-27 雀巢产品技术援助有限公司 用于改善婴儿或幼儿粪便稠度或频率的组合物
ES2886951T3 (es) 2015-09-14 2021-12-21 Glycom As Composición para su uso en la modulación de la microbiota
US10780103B2 (en) 2015-10-28 2020-09-22 Glycom A/S Synthetic composition and method for modulating emotion and mood disorders
PL3368046T3 (pl) 2015-10-28 2022-11-28 Glycom A/S Syntetyczna kompozycja i sposób modulowania funkcji mózgu i zachowania
WO2017144062A1 (en) * 2016-02-24 2017-08-31 Glycom A/S Synthetic composition for microbiota modulation
ES2924137T3 (es) 2016-05-05 2022-10-04 Glycom As Composición que comprende HMOS para uso en el tratamiento de la hipersensibilidad y/o dolor visceral mediados por mastocitos
DK3452050T3 (da) * 2016-05-05 2023-02-20 Glycom As Composition comprising hmos for the treatment of noninfectious diarrhoea
US11224605B2 (en) 2016-05-19 2022-01-18 Glycom A/S Synthetic composition
MX2018015187A (es) * 2016-08-04 2019-04-24 Nestec Sa Composiciones nutricionales con 2fl y lnnt para su uso en la prevencion y/o tratamiento de la diarrea no causada por rotavirus mediante la accion en la disbiosis de la microbiota intestinal.
BR112019005329A2 (pt) * 2016-09-19 2019-06-18 Prolacta Bioscience, Inc. composições de oligossacarídeos de leite humano purificadas
AU2016101768B4 (en) * 2016-09-28 2017-02-02 Grech, Brian James DR Treatment for Irritable Bowel Syndrome
GB201617519D0 (en) * 2016-10-14 2016-11-30 Genetic Analysis As A companion diagnostic method for use in the treatment of irritable bowel syndrome with dietary interventions or faecal microbiota transplant
CN106668034A (zh) * 2017-01-13 2017-05-17 华中科技大学同济医学院附属协和医院 L‑岩藻糖在治疗消化道病变的药品和保健品中应用
WO2018157900A1 (en) * 2017-03-01 2018-09-07 Glycom A/S Synthetic composition for microbiota modulation
EP3716984B1 (en) * 2017-11-30 2024-03-20 Glycom A/S Mixture of hmos for treating wheat sensitivity
US11602545B2 (en) * 2017-12-05 2023-03-14 Glycom A/S Human milk oligosaccharides for treating migraine
SG11202004659QA (en) * 2017-12-08 2020-06-29 Jennewein Biotechnologie Gmbh Spray-dried sialyllactose
CN112423603A (zh) 2018-07-12 2021-02-26 N·V·努特里奇亚 用于改善肠屏障完整性的营养组合物、组合物的制备以及治疗方法
EP3897663A4 (en) * 2018-12-21 2022-09-07 Glycom A/S COMPOSITION AND METHOD FOR PROMOTING HEALING OF THE INTESTINAL BARRIER
CA3161861A1 (en) * 2019-11-27 2021-06-03 Glycom A/S Mixture of hmos
IT201900023016A1 (it) * 2019-12-04 2021-06-04 Alesco Srl Formulazioni comprendenti un minerale e un polisaccaride, loro composizioni e loro uso nella supplementazione di detto minerale
US12533368B2 (en) 2019-12-06 2026-01-27 Societe Des Produits Nestle S.A. Compositions for use in the reduction of pain and/or perception of pain in infants and young children
AU2020399200A1 (en) * 2019-12-11 2022-06-09 Société des Produits Nestlé S.A. Compositions for use in the reduction of nociception and other health benefits in infants and young children
WO2022124324A1 (ja) * 2020-12-09 2022-06-16 株式会社明治 アシディプロピオニバクテリウム属菌またはその処理物を含んでなる組成物
WO2022155126A1 (en) * 2021-01-12 2022-07-21 Intrinsic Medicine, Inc. Methods and compositions for supporting human health during space travel
US11712445B2 (en) 2021-04-30 2023-08-01 Sourabh Kharait Compositions and methods for improving gastrointestinal function in subjects with renal disease
US20250213600A1 (en) * 2022-03-18 2025-07-03 Meiji Co., Ltd. Composition for controlling growth of bacteria in the intestinal tract and use thereof
CN119584872A (zh) * 2022-07-21 2025-03-07 田中惠 封入有烟酰胺单核苷酸的用于改善肠道菌群的肠溶性胶囊制剂
WO2025196272A1 (en) * 2024-03-22 2025-09-25 Dsm Ip Assets B.V. Combination of mixtures of hmos with mfgm and their use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120172319A1 (en) * 2010-12-31 2012-07-05 Abbott Laboratories Methods for decreasing the incidence of necrotizing enterocolitis in infants, toddlers, or children using human milk oligosaccharides
WO2012106665A2 (en) * 2011-02-04 2012-08-09 The Regents Of The University Of California Disialyllacto-n-tetraose (dslnt) or variants, isomers, analogs and derivatives thereof to prevent or inhibit bowel disease
WO2013154725A1 (en) * 2012-04-13 2013-10-17 Trustees Of Boston College Prebiotic compositions and methods of use

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663321A (en) 1984-06-26 1987-05-05 Merck & Co., Inc. Triazolobenzodiazepines and pharmaceutical use
FR2796082B1 (fr) 1999-07-07 2003-06-27 Centre Nat Rech Scient Procede de production d'oligosaccharides
WO2004026257A2 (en) 2002-09-20 2004-04-01 The Board Of Regents Of The University Of Texas System Treatment of irritable bowel syndrome and related bowel diseases
GB0312365D0 (en) 2003-05-30 2003-07-02 Univ Aston Novel 3-substituted-1, 4-benzodiazepines
AU2005288080B2 (en) * 2004-09-28 2011-10-13 Otsuka Pharmaceutical Co., Ltd. Carbostyril compound
WO2007101862A1 (en) 2006-03-09 2007-09-13 Centre National De La Recherche Scientifique (Cnrs) Method of producing sialylated oligosaccharides
US20110104282A1 (en) 2008-04-25 2011-05-05 Karolinska Institutet Innovations Ab New Therapy of Treatment of the Irritable Bowel Syndrome
CN102459294A (zh) 2009-04-07 2012-05-16 格礼卡姆股份公司 2’-o-岩藻糖基乳糖的合成
ES2651067T3 (es) 2009-07-06 2018-01-24 Children's Hospital Medical Center Inhibición de la inflamación con oligosacáridos de la leche
EP3241836B1 (en) 2010-02-19 2024-10-30 Glycom A/S Polymorph of a tetrasaccharide containing nacetyl-lactosamine
WO2011100979A1 (en) 2010-02-19 2011-08-25 Glycom A/S Production of 6'-o-sialyllactose and intermediates
US9119869B2 (en) * 2010-04-29 2015-09-01 Ronald J. Shebuski Mucin derived polypeptides
US9200091B2 (en) * 2010-07-12 2015-12-01 The Regents Of The University Of California Bovine milk oligosaccharides
AU2011278236A1 (en) 2010-07-16 2013-02-07 Glycom A/S Derivatization of oligosaccharides
EP2454948A1 (en) 2010-11-23 2012-05-23 Nestec S.A. Oligosaccharide mixture and food product comprising this mixture, especially infant formula
MY191538A (en) * 2010-12-31 2022-06-30 Abbott Lab Human milk oligosaccharides to promote growth of beneficial bacteria
US20120171166A1 (en) 2010-12-31 2012-07-05 Abbott Laboratories Synbiotic combination of probiotic and human milk oligosaccharides to promote growth of beneficial microbiota
WO2012113404A1 (en) 2011-02-21 2012-08-30 Glycom A/S Novel glycosyl phosphites
CN103443113A (zh) 2011-03-18 2013-12-11 格力康公司 新型含岩藻糖的糖类衍生物的合成
CN103562214B9 (zh) 2011-05-13 2016-12-14 格力康公司 人乳寡糖(hmo)或其前体的多样化
WO2012155916A1 (en) 2011-05-13 2012-11-22 Glycom A/S Manufacture of lacto-n-tetraose
CN103562401A (zh) 2011-05-13 2014-02-05 格力康公司 产生人乳寡糖(hmo)或其前体的方法
EP2760875A4 (en) 2011-09-30 2015-08-26 Glycom As SYNTHESIS OF HMO NUCLEAR STRUCTURES
WO2013091660A1 (en) 2011-12-23 2013-06-27 Glycom A/S A method for obtaining crystalline lacto-n-tetraose and lacto-n-neotetraose precursors and mixtures thereof
WO2013139344A1 (en) 2012-03-20 2013-09-26 Glycom A/S Synthesis of the trisaccharide 3-o-fucosyllactose and intermediates thereof
MY168661A (en) * 2012-03-27 2018-11-28 Abbott Lab Methods for modulating cell-mediated immunity using human milk oligosaccharides
JPWO2013161693A1 (ja) * 2012-04-27 2015-12-24 トライエックス・バイオメディカル株式会社 腸内細菌異常増殖による過敏性腸症候群の診断剤及び診断法
WO2015077233A1 (en) 2013-11-19 2015-05-28 Abbott Laboratories Methods for preventing or mitigating acute allergic responses using human milk oligosaccharides
HK1231398A1 (zh) * 2014-04-08 2017-12-22 Abbott Laboratories 使用人乳寡糖增强对病原体的粘膜先天免疫反应和/或检测的方法
EP3212197A4 (en) 2014-10-29 2018-07-11 Glycom A/S Synthetic composition and method for treating irritable bowel syndrome
US11040050B2 (en) 2014-10-29 2021-06-22 Glycom A/S Composition comprising HMSs/HMOs and use thereof
US11040049B2 (en) 2014-10-29 2021-06-22 Glycom A/S Composition comprising HMSs/HMOs and use thereof
ES2886951T3 (es) 2015-09-14 2021-12-21 Glycom As Composición para su uso en la modulación de la microbiota
TWI715424B (zh) * 2020-01-22 2021-01-01 長春石油化學股份有限公司 電解銅箔、電極及包含其之鋰離子電池

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120172319A1 (en) * 2010-12-31 2012-07-05 Abbott Laboratories Methods for decreasing the incidence of necrotizing enterocolitis in infants, toddlers, or children using human milk oligosaccharides
WO2012106665A2 (en) * 2011-02-04 2012-08-09 The Regents Of The University Of California Disialyllacto-n-tetraose (dslnt) or variants, isomers, analogs and derivatives thereof to prevent or inhibit bowel disease
WO2013154725A1 (en) * 2012-04-13 2013-10-17 Trustees Of Boston College Prebiotic compositions and methods of use

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111526879A (zh) * 2017-11-02 2020-08-11 格礼卡姆股份公司 用于减少或预防疲劳和/或改善注意力或专注力的一种或多种hmo
CN111432661A (zh) * 2017-12-22 2020-07-17 雀巢产品有限公司 用途是用于减少婴儿和幼儿的伤害感觉的组合物
CN111683666A (zh) * 2017-12-22 2020-09-18 格礼卡姆股份公司 预防或减少伤害感受的包含hmo的组合物
CN113194960A (zh) * 2018-12-19 2021-07-30 格礼卡姆股份公司 用于治疗使用低fodmap饮食的人的组合物和方法
US12233079B2 (en) 2018-12-19 2025-02-25 Glycom A/S Composition and method for treating humans using low-fodmap diets
CN113939340A (zh) * 2019-06-12 2022-01-14 格礼卡姆股份公司 用于预防、管理或治疗偏头痛相关症状的人乳寡糖及其组合物
CN114401642A (zh) * 2019-09-18 2022-04-26 科汉森母乳低聚糖股份有限公司 含有人乳寡糖的谷物组合物
CN114728015A (zh) * 2019-11-14 2022-07-08 格礼卡姆股份公司 用于平衡肠中胆汁酸谱的合成组合物
CN116528695A (zh) * 2020-12-04 2023-08-01 格礼卡姆股份公司 用于支持睡眠模式的成熟或改善的人乳寡糖
CN120570904A (zh) * 2025-07-14 2025-09-02 苏州一兮生物技术有限公司 一种用于预防和/或治疗腹泻的组合物及其用途

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JP7182872B2 (ja) 2022-12-05
WO2016066175A1 (en) 2016-05-06
JP2021152062A (ja) 2021-09-30
EP3212197A1 (en) 2017-09-06
CN115364113A (zh) 2022-11-22
EP3212197A4 (en) 2018-07-11
JP7301093B2 (ja) 2023-06-30
US11833165B2 (en) 2023-12-05
US20160346303A1 (en) 2016-12-01
US20180169122A1 (en) 2018-06-21
JP2017533915A (ja) 2017-11-16
US20210308158A1 (en) 2021-10-07
US11026959B2 (en) 2021-06-08

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