CN107050170A - A kind of raising pig, preparation of chicken growth performance and preparation method thereof - Google Patents

A kind of raising pig, preparation of chicken growth performance and preparation method thereof Download PDF

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Publication number
CN107050170A
CN107050170A CN201710122338.8A CN201710122338A CN107050170A CN 107050170 A CN107050170 A CN 107050170A CN 201710122338 A CN201710122338 A CN 201710122338A CN 107050170 A CN107050170 A CN 107050170A
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preparation
parts
pig
auxiliary material
growth performance
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Inventor
黄宏业
胡庭俊
王秋华
杨善忠
唐廷崇
彭健波
何家康
韦英益
李晓平
陶卿
涂丽云
吴文健
韦盈吉
农莹
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GUANGXI BDX ANIMAL DRUGS CO Ltd
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GUANGXI BDX ANIMAL DRUGS CO Ltd
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Priority to CN201710122338.8A priority Critical patent/CN107050170A/en
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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Abstract

The present invention relates to veterinary drug technical field, specifically a kind of raising pig, the preparation of chicken growth performance and preparation method thereof.The present invention includes the raw material of following parts by weight:II 50~90 parts of 150~220 parts of picria fel tarrae, I 100~150 parts of auxiliary material or auxiliary material or III 4~6 parts of auxiliary material, appropriate amount of water, its preparation method include extract solution preparation, extract powder and prepared and preparation 3 steps of preparation.The present invention improves pig, the defect of chicken growth performance for abuse antimicrobial at present, develops herbal medicine picria fel tarrae preparation, safely, effectively, quality controllable, improves pig, chicken growth performance effect significantly, and natural nuisance-free, cultivates and promotes the use of beneficial to non-resistant ecological.

Description

A kind of raising pig, preparation of chicken growth performance and preparation method thereof
Technical field
The present invention relates to veterinary drug technical field, specifically a kind of raising pig, the preparation of chicken growth performance and its preparation Method.
Background technology
Aquaculture is the key industries of increasing peasant income, but livestock and poultry often brings huge loss to raiser, turns into The key factor for hindering aquaculture to develop in a healthy way.The plant of scale is generally largely using antibiotic prophylaxis and treatment livestock and poultry Bacterium infection, although have certain effect to control livestock and poultry, but largely there is larger harm using antibiotic:Its First, abuse of antibiotics can make bacterium produce drug resistance, and directly endanger human health;Secondly, it is a large amount of using antibiotic bring compared with Strong toxic side effect, directly injures animal body;Thirdly, the abuse of antibiotic, can largely kill animal body in normal bacteria, reduction Resistance, allows pathogenic bacteria to take advantage of a weak point, and then causes suprainfection;Antibiotic four, is widely used, causes breast, meat products medicine Thing is remained and cultivation surrounding enviroment pollution, harm human health.Therefore, developing ecology cultivate, using safely, effectively, noresidue, The herbal medicine of drug resistance is not likely to produce to substitute conventional antibiotic, with wide market prospects.
Picria fel tarrae is goatweed picria fel tarrae(Picria fel-tarrae Lour)Drying herb, alias eel grass, Radix Picriae felterrae, tetracycline grass.Picria fel tarrae bitter, it is cold in nature, it is that Guangxi is most characteristic with clearing heat and detoxicating, swelling and pain relieving function One of Chinese herbal medicine.Modern pharmacology shows that the medical instrument has preferable antiinflammatory action and broad-spectrum antibacterial action.Resist in vitro in picria fel tarrae Found in bacterium Experiment on Function, picria fel tarrae decocting liquid there are different journeys to Escherichia coli, salmonella, Pasteurella, streptococcus etc. The inhibitory action of degree, wherein the effect to streptococcus, Pasteurella is stronger.
In the Chinese literature that the current country is published, it there are no with picria fel tarrae to pig, the influence aspect of chicken growth performance Document report.Therefore, a kind of Chinese veterinary drug preparation using picria fel tarrae as raw material is developed, pig, the growth performance of chicken is improved, promoted Livestock birds health is grown up, and has very positive effect to improving cultivation success rate and economic benefit.
The content of the invention
The purpose of the present invention is that the problem for overcoming abuse of antibiotics in existing cultural technique improves pig, chicken life there is provided one kind The preparation of long performance.
The solution of the present invention is by being achieved in that:
A kind of raising pig, the preparation of chicken growth performance, include the raw material of following parts by weight:150~220 parts of picria fel tarrae, auxiliary material I 100~150 parts or II 50~90 parts of auxiliary material or III 4~6 parts of auxiliary material, appropriate amount of water, the picria fel tarrae are picria fel tarrae medicine materical crude slice, are bitter profound Ginseng is dried herb and formed through over cleaning, segment, drying processing, and the auxiliary material I is sucrose and dextrin, and auxiliary material I is mainly as particle The flavor enhancement and excipient of agent, the auxiliary material II are the one or more in starch, DEXTROSE ANHYDROUS, silica, auxiliary Material II is mainly as the excipient of pulvis, and the auxiliary material III is sodium benzoate and polysorbate, and auxiliary material III is mainly as oral liquid Preservative and solubilizer.
2nd, a kind of raising pig, the preparation method of the preparation of chicken growth performance, it is characterised in that comprise the following steps:
(1) prepared by extract solution:Take 150~220 parts of picria fel tarrae medicine materical crude slice to be placed in extractor, add water 150~2200 parts, 90~ Heating extraction 60 minutes at 95 DEG C, 300 mesh filter-cloth filterings take filtrate, repeat said extracted process 2 times, and merging filtrate obtains bitter profound Join extract solution;
(2) prepared by extract powder:Picria fel tarrae extract solution obtained by step (1) is condensed into phase in the case where MPa, 60-65 DEG C of 0.06-0.08 To the concentrate that density is 1.02, by concentrate under 20000 revs/min through 30 μm of filter membrane refined filtrations, be condensed into phase at 70 DEG C To the thick paste that density is 1.15, thick paste is spray-dried under conditions of 120 DEG C of EAT, 70 DEG C of leaving air temp, obtained Extract powder;
(3) prepared by preparation:Extract powder obtained by step (2) and auxiliary material I are prepared into granule, or pulvis is prepared into auxiliary material II, Or oral liquid is prepared into auxiliary material III, it is improved pig, the preparation of chicken growth performance.
3rd, pig, the preparation method of the preparation of chicken growth performance are improved as claimed in claim 2, it is characterised in that described Granule its method of being prepared into be that auxiliary material I is added in extract powder:20 parts of sucrose, 60 parts of dextrin, stir, and add water 8 Part, softwood is made in 5 minutes in stirring, and softwood is crossed into 14 mesh sieves obtains wet granular, and wet granular is put into boiling drier and boiled Drying is risen, EAT≤100 DEG C are controlled, the time is 15 minutes, obtains the dry particl of water content≤5%, dry particl is placed in Whole grain is carried out in the mesh sieve of granulator 12, pig, the granule of chicken growth performance is improved.
4th, pig, the preparation method of the preparation of chicken growth performance are improved as claimed in claim 2, it is characterised in that described Pulvis its method of being prepared into be that auxiliary material II is added in extract powder:Starch or 80 parts of DEXTROSE ANHYDROUS, 5 parts of silica, are stirred Mix uniform, obtain picria fel tarrae pulvis, be improved pig, the pulvis of chicken growth performance.
5th, pig, the preparation method of the preparation of chicken growth performance are improved as claimed in claim 2, it is characterised in that described Oral liquid its method of being prepared into be that 100 parts of deionized waters are added in extract powder, heating, which is boiled to extract powder, to be completely dissolved into Relative density is 1.05~1.07 solution, is cooled to room temperature, and it is 70% to add ethanol to concentration of alcohol, stands 48-60 hours, Filtering, filtrate recycling ethanol obtains the supernatant without ethanol, and auxiliary material III is added in supernatant:1.5~2 parts of sodium benzoate, 3~4 parts of polysorbate, adds 150~200 parts of deionized waters, stirs, through 30~50 μm of filter membrane refined filtrations, take filtrate, fills Envelope, sterilizes, and packaging is improved pig, the oral liquid of chicken growth performance.
The pharmacology that the present invention is realized is:Picria fel tarrae, is goatweed picria fel tarraePicria felterraeLour. Herb is dried, its bitter is cold in nature;Return lung, stomach, Liver Channel;With clearing heat and detoxicating, the effect of swelling and pain relieving;Anemopyretic cold is cured mainly, is swallowed Larynx swells and ache, larynx numbness, mumps, epigastric pain, dysentery etc..
The present invention possesses following good result:
1st, the present invention improves pig, the defect of chicken growth performance for abuse antimicrobial at present, develops herbal medicine picria fel tarrae system Agent, safely, effectively, quality controllable, improves pig, chicken growth performance effect significantly, and natural nuisance-free, is cultivated beneficial to non-resistant ecological Promote the use of.
2nd, picria fel tarrae preparation of the invention can significantly reduce feed-weight ratio, increase economic efficiency.
3rd, picria fel tarrae preparation of the invention is easy to use, can with the mixed drink of drinking water, or with feed mixed feeding.
4th, planted extensively in the raw material sources very abundant that the present invention is used, Guangxi District, cost of material is low.
5th, preparation technology of the present invention is simple, and production cost is relatively low, with the stronger market competitiveness, economic benefit and society Benefit is notable.
Embodiment
With reference to embodiments with a kind of raising pig of the description present invention, the preparation of chicken growth performance and preparation method thereof, this A little descriptions are not that present invention is further limited.
Embodiment 1
A kind of raising pig, the preparation of chicken growth performance, include the raw material of following parts by weight:176 parts of picria fel tarrae, II 85 parts of auxiliary material, Appropriate amount of water, the picria fel tarrae is picria fel tarrae medicine materical crude slice, is that picria fel tarrae drying herb is formed through over cleaning, segment, drying processing, described Auxiliary material II is starch and silica.
Above-mentioned raising pig, the preparation method of the preparation of chicken growth performance, comprise the following steps:
(1) prepared by extract solution:Take 176 parts of picria fel tarrae medicine materical crude slice to be placed in extractor, add water 800 parts, the heating extraction 60 at 90 DEG C Minute, 300 mesh filter-cloth filterings take filtrate, repeat said extracted process 2 times, and merging filtrate obtains picria fel tarrae extract solution;
(2) prepared by extract powder:Picria fel tarrae extract solution obtained by step (1) is condensed into relative density at 0.06 MPa, 60 DEG C is 1.02 concentrate, concentrate is condensed into relative density through 30 μm of filter membrane refined filtrations, at 70 DEG C under 20000 revs/min is 1.15 thick paste, thick paste is spray-dried under conditions of 120 DEG C of EAT, 70 DEG C of leaving air temp, extract powder is obtained;
(3) prepared by preparation:Extract powder obtained by step (2) and auxiliary material II are prepared into pulvis, auxiliary material II is added in extract powder:Form sediment 80 parts of powder, 5 parts of silica, stir, obtain picria fel tarrae pulvis, are improved pig, the pulvis of chicken growth performance.
Embodiment 2
A kind of raising pig, the preparation of chicken growth performance, include the raw material of following parts by weight:195 parts of picria fel tarrae, II 70 parts of auxiliary material, Appropriate amount of water, the picria fel tarrae is picria fel tarrae medicine materical crude slice, is that picria fel tarrae drying herb is formed through over cleaning, segment, drying processing, described Auxiliary material II is DEXTROSE ANHYDROUS and silica.
Above-mentioned raising pig, the preparation method of the preparation of chicken growth performance, comprise the following steps:
(1) prepared by extract solution:Take 195 parts of picria fel tarrae medicine materical crude slice to be placed in extractor, add water 1100 parts, the heating extraction at 95 DEG C 60 minutes, 300 mesh filter-cloth filterings took filtrate, repeat said extracted process 2 times, and merging filtrate obtains picria fel tarrae extract solution;
(2) prepared by extract powder:Picria fel tarrae extract solution obtained by step (1) is condensed into relative density at 0.08 MPa, 65 DEG C is 1.02 concentrate, concentrate is condensed into relative density through 30 μm of filter membrane refined filtrations, at 70 DEG C under 20000 revs/min is 1.15 thick paste, thick paste is spray-dried under conditions of 120 DEG C of EAT, 70 DEG C of leaving air temp, extract powder is obtained;
(3) prepared by preparation:Extract powder obtained by step (2) and auxiliary material II are prepared into pulvis, auxiliary material II is added in extract powder:Nothing 60 parts of water glucose, 0 part of silica 1, stir, obtain picria fel tarrae pulvis, are improved pig, the powder of chicken growth performance Agent.
Embodiment 3
A kind of raising pig, the preparation of chicken growth performance, include the raw material of following parts by weight:150 parts of picria fel tarrae, I 80 parts of auxiliary material, Appropriate amount of water, the picria fel tarrae is picria fel tarrae medicine materical crude slice, is that picria fel tarrae drying herb is formed through over cleaning, segment, drying processing, described Auxiliary material I is sucrose and dextrin.
Above-mentioned raising pig, the preparation method of the preparation of chicken growth performance, comprise the following steps:
(1) prepared by extract solution:Take 150 parts of picria fel tarrae medicine materical crude slice to be placed in extractor, add water 450 parts, the heating extraction 60 at 93 DEG C Minute, 300 mesh filter-cloth filterings take filtrate, repeat said extracted process 2 times, and merging filtrate obtains picria fel tarrae extract solution;
(2) prepared by extract powder:Picria fel tarrae extract solution obtained by step (1) is condensed into relative density at 0.07MPa, 63 DEG C is 1.02 concentrate, concentrate is condensed into relative density through 30 μm of filter membrane refined filtrations, at 70 DEG C under 20000 revs/min is 1.15 thick paste, thick paste is spray-dried under conditions of 120 DEG C of EAT, 70 DEG C of leaving air temp, extract powder is obtained;
(3) prepared by preparation:Extract powder obtained by step (2) and auxiliary material I are prepared into granule, auxiliary material I is added in extract powder:Sugarcane Sugared 20 parts, 60 parts of dextrin, stir, and add 8 parts of water, and softwood is made in 5 minutes in stirring, and softwood is crossed into 14 mesh sieves obtains wet Grain, wet granular is put into boiling drier and carries out fluidized drying, controls EAT≤100 DEG C, and the time is 15 minutes, is obtained The dry particl of water content≤5%, dry particl is placed in the mesh sieve of granulator 12 and carries out whole grain, is improved pig, chicken growth performance Granule.
Embodiment 4
A kind of raising pig, the preparation of chicken growth performance, include the raw material of following parts by weight:220 parts of picria fel tarrae, auxiliary material III 4.5 Part, appropriate amount of water, the picria fel tarrae are picria fel tarrae medicine materical crude slice, are that picria fel tarrae drying herb is formed through over cleaning, segment, drying processing, The auxiliary material III is sodium benzoate and polysorbate.
Above-mentioned raising pig, the preparation method of the preparation of chicken growth performance, comprise the following steps:
(1) prepared by extract solution:Take 220 parts of picria fel tarrae medicine materical crude slice to be placed in extractor, add water 2200 parts, the heating extraction at 92 DEG C 60 minutes, 300 mesh filter-cloth filterings took filtrate, repeat said extracted process 2 times, and merging filtrate obtains picria fel tarrae extract solution;
(2) prepared by extract powder:Picria fel tarrae extract solution obtained by step (1) is condensed into relative density at 0.06 MPa, 65 DEG C is 1.02 concentrate, concentrate is condensed into relative density through 30 μm of filter membrane refined filtrations, at 70 DEG C under 20000 revs/min is 1.15 thick paste, thick paste is spray-dried under conditions of 120 DEG C of EAT, 70 DEG C of leaving air temp, extract powder is obtained;
(3) prepared by preparation:Extract powder obtained by step (2) and auxiliary material III are prepared into oral liquid, adding 100 parts in extract powder goes Ionized water, heating, which is boiled to extract powder, is completely dissolved into the solution that relative density is 1.05, is cooled to room temperature, adds ethanol to second Determining alcohol is 70%, stands 48 hours, filtering, and filtrate recycling ethanol obtains the supernatant without ethanol, is added in supernatant Auxiliary material III:1.5 parts of sodium benzoate, 3 parts of polysorbate, add 180 parts of deionized waters, stir, through 30 μm of filter membrane refined filtrations, Filtrate is taken, embedding sterilizes, and packaging is improved pig, the oral liquid of chicken growth performance.
Experimental clinical test
(One)Influence of the preparation of the present invention to piglet growth performance
1st, trial drug:Prepared by embodiment 1 improves pig, the pulvis of chicken growth performance.
2nd, subjects:The healthy weanling pig 60 of 30 ages in days is selected, healthy, male and female is random, kind:(Du × length × big)Tri-crossbreeding.
3rd, test site:That Ma pig farm of Guangxi
4th, test period:On April 15th, 2016 to May 15.
5th, test method:
(1)Packet:60 piglets are randomly divided into 2 columns, per 30, column, wherein 1 column is trial drug group, 2 columns are blank control Group.
(2)Dosage regimen:Trial drug group adds the raising pig of the preparation of embodiment 1, the powder of chicken growth performance in daily ration Agent 0.1%, is used in conjunction 20.
(3)Experimental condition:Test pig is raised in same pig house, free choice feeding and drinking-water, the feeding management such as epidemic prevention, expelling parasite According to it is conventional it is identical in the case of carry out.Basal diet is the small pig feed of complete diet pellet without any medicine.
(4)Body weight determination:In on-test(1st day)And off-test(31st day)When to each group test pig carry out early morning Weigh on an empty stomach, calculate average daily gain, average daily feed intake and feed-weight ratio.
6th, result and analysis:
Influence of the invention formulation of table 1 to pig production performance
Project Beginning counterpoise (kg) Last counterpoise (kg) Average weight increasing a day (g) Average daily feed intake (g) Feed-weight ratio
Trial drug group 8.12±0.68 20.68±2.41 418.67±87.02* 578.25 1.38*
Blank control group 8.07±0.76 18.74±2.72 355.57±62.76 559.67 1.57
Note:Compared with control group, * represent significant difference (P<0.05), * * represent difference extremely significantly (P<0.01)。
From table 1, picria fel tarrae particle can significantly improve the Average weight increasing a day of child care pig, and reduce the feed-weight ratio of child care piglet, two Person is compared with blank control group, difference significantly (P< 0. 05).
7th, conclusion:Picria fel tarrae, which dissipates, can improve daily gain in pigs, reduction feed-weight ratio, the effect for the pig growth performance that is significantly increased.
(Two)Influence of the invention formulation to chicken growth performance
1st, trial drug:Prepared by embodiment 4 improves pig, the oral liquid of chicken growth performance.
2nd, subjects:The plumage of 1 Japanese instar chickling of Nanning chicken house 150, kind:Sanhuang chicken, body weight 29-32g.
3rd, test site:Guangxi veterinary drug preparation Engineering Technical Research Centre Animal Lab.
4th, test period:On May 20th, 2015 to June 10.
5th, test method:
(1)Packet:The Japanese instar chickling of 150 plumage 1 is randomly divided into 3 groups, respectively trial drug group, control drug group and blank control Group, is raised per the cage of component 2, per the plumage of cage 25.
(2)Dosage regimen:Trial drug group adds the raising pig of the preparation of embodiment 4, the mouth of chicken growth performance in drinking-water 0.025g/ days plumages of liquid are taken, are used in conjunction 20.
(3)Experimental condition:Test chicken is raised for two layers in same environment single cage, heat-insulating lamp insulation(38℃), free choice feeding, from By drinking water.Basal diet is the chicken complete diet pellet without any medicine.
(4)Body weight determination:Early morning empty stomach is carried out to each group test chicken when experiment the initial 1st, 7,14,21 age in days to weigh, Calculate the body weight increase rate in each stage.
6th, result and analysis:
Stage Gain weight (Mean ± SD) of the invention formulation of table 2 to experimental animal(n=50)
Note:* represents that compared with blank control group, difference is extremely notable(P<0.01);## represented compared with drug control group, difference It is extremely notable(P <0.01);
* represent compared with blank control group, significant difference(P<0.05);# represented compared with drug control group, significant difference(P < 0.05).
As shown in Table 2, in 0~7 age in days stage, the body weight increase rate pole of trial drug group is significantly higher than blank control group and medicine Control group(P <0.01);In 8~14 age in days stages, the body weight increase rate of trial drug group is compareed with blank control group and medicine Group is compared, and is decreased, but difference is not notable(P > 0.05);In 15~21 ages in days, the body weight increase rate of trial drug group Pole is significantly higher than blank control group and drug control group(P <0.01).
7th, conclusion:Invention formulation significantly improves the growth performance of test chicken.
Applying clinical is tested
(One)The scattered influence to pig growth performance of picria fel tarrae is added in daily ration
1st, trial drug:Prepared by embodiment 1 improves pig, the pulvis of chicken growth performance.
2nd, subjects:25-30 ages in days piglet 150 is selected, healthy, male and female is random, kind:(Du × length × big) Tri-crossbreeding.
3rd, test site:Guangxi golden light pig farm
4th, test period:On June 18th, 2016 to July 18.
5th, test method:
(1)Packet:150 piglets are randomly divided into 6 columns, per 25, column, wherein 1,2 columns are trial drug group, 3,4 columns are medicine Control group, 5,6 columns are blank control group.
(2)Dosage regimen:Trial drug group adds the raising pig of the preparation of embodiment 1, the powder of chicken growth performance in daily ration Agent 0.1%, is used in conjunction 20.
(3)Experimental condition:Test pig is raised in same pig house, free choice feeding and drinking-water, the feeding management such as epidemic prevention, expelling parasite According to it is conventional it is identical in the case of carry out.Basal diet is the small pig feed of complete diet pellet without any medicine.
(4)Body weight determination:In on-test(1st day)And off-test(31st day)When to each group test pig carry out early morning Weigh on an empty stomach, calculate average daily gain, average daily feed intake and feed-weight ratio.
6th, result and analysis:
The picria fel tarrae of table 3 dissipates the influence to the production performance of pig
Project Beginning counterpoise (kg) Last counterpoise (kg) Average weight increasing a day (g) Average daily feed intake (g) Feed-weight ratio Diarrhea rate(%)
Trial drug group 7.49±0.55 19.02±2.62 384.49±82.72* 551.91 1.43* 6.00**
Drug control group 7.69±0.99 18.90±3.91 373.4±86.86 546.05 1.46 8.00*
Blank control group 7.75±1.26 18.38±2.45 354.3±62.76 547.53 1.55 16.00
Note:Compared with control group, alphabetical * represents significant difference (P<0.05), alphabetical * * represent difference extremely significantly (P<0.01).
From table 3, invention formulation can significantly improve the daily gain of child care pig, be compared with blank control group, significant difference (P < 0.05);Invention formulation can reduce the feed-weight ratio of child care pig, be compared with blank control group, significant difference (P< 0.05);This Invention preparation can reduce the diarrhea rate of child care pig, be compared with blank control group, difference extremely significantly (P< 0.01);
7th, conclusion:Invention formulation can improve child care daily gain in pigs, reduction feed-weight ratio, reduce diarrhoea, the pig that is significantly increased growth The effect of performance.
(Two)Influence of the invention formulation to chicken growth performance
1st, trial drug:Prepared by embodiment 3 improves pig, the granule of chicken growth performance.
2nd, experimental animal:Select the numb chicken in healthy 1 age in days Guangxi of Nanning City's chicken house.
3rd, test site:Guangxi chicken house.
4th, test period:On November 13,9 days to 2015 October in 2015.
5th, test method:
(1)Packet:The age in days healthy chick of 500 plumage 1 is randomly divided into 5 groups, every group of 100 plumages are that trial drug is high, medium and low respectively Dosage group, drug control group and blank control group.
(2)Dosage regimen:The high, medium and low dosage group of trial drug distinguishes raising prepared by embodiment 3 in basal diet Pig, the granule 0.70%, 0.35%, 0.175% of chicken growth performance, are used in conjunction 35.
(3)Experimental condition:Test fowl raising during 1-21 ages in days be equipped with the chicken brooding house of automatic temperature control system, 1 age in days When start to feed experiment daily ration, free choice feeding and drinking-water, the feeding management such as insulation, ventilation, illumination is with producing routine.During experiment It is immunized simultaneously by production is conventional, each group is in addition to daily ration is constituted during whole experiment, other rearing conditions all sames.
(4)Body weight determination:Early morning empty stomach is carried out to each group test chicken when experiment the initial 1st, 21,35 age in days to weigh, and is counted Calculate corresponding average daily gain.
6th, result and analysis:
The picria fel tarrae of table 4 dissipates the influence to test chicken average daily gain(g)
Group First starting weight 1d 21d 35d
Trial drug group 31.21±0.59 7.59±0.19 9.74±0.41*
Drug control group 31.33±0.16 7.06±0.64 9.22±0.84
Blank control group 31.13±0.15 7.01±0.45 8.63±0.56
Note:Compared with control group, alphabetical * represents significant difference (P<0.05), alphabetical * * represent difference extremely significantly (P<0.01).
Table 2 is visible, and average daily gain of the trial drug group chicken in 35 age in days is significantly higher than blank control group(P< 0.05), during 21 age in days, trial drug group chicken also has the trend higher than blank control group, but difference is not notable(P>0.05);Examination Medicine group is tested compared with drug control group, the 21st age in days and the 35th equal difference of age in days is not notable(P>0.05).As a result show, Invention formulation is added in daily ration can significantly improve the average daily gain of test chicken, and effect is slightly better than drug control group.
7th, conclusion:Invention formulation significantly improves the growth performance of test chicken.
Experimental clinical test and applying clinical result of the test show that invention formulation can significantly improve experimental animal above Daily gain, reduce diarrhoea, and reduce feed-weight ratio, significantly improve the growth performance of experimental animal.

Claims (5)

1. a kind of raising pig, the preparation of chicken growth performance, it is characterised in that include the raw material of following parts by weight:Picria fel tarrae 150 II 50~90 parts of~220 parts, I 100~150 parts of auxiliary material or auxiliary material or III 4~6 parts of auxiliary material, appropriate amount of water, the picria fel tarrae are bitter profound Join medicine materical crude slice, be picria fel tarrae dry herb through over cleaning, segment, drying processing form, the auxiliary material I be sucrose and dextrin, it is described Auxiliary material II is the one or more in starch, DEXTROSE ANHYDROUS, silica, and the auxiliary material III is sodium benzoate and poly- mountain Pear ester.
2. a kind of raising pig, the preparation method of the preparation of chicken growth performance, it is characterised in that comprise the following steps:
(1) prepared by extract solution:Take 150~220 parts of picria fel tarrae medicine materical crude slice to be placed in extractor, add water 150~2200 parts, 90~ Heating extraction 60 minutes at 95 DEG C, 300 mesh filter-cloth filterings take filtrate, repeat said extracted process 2 times, and merging filtrate obtains bitter profound Join extract solution;
(2) prepared by extract powder:Picria fel tarrae extract solution obtained by step (1) is condensed into phase in the case where MPa, 60-65 DEG C of 0.06-0.08 To the concentrate that density is 1.02, by concentrate under 20000 revs/min through 30 μm of filter membrane refined filtrations, be condensed into phase at 70 DEG C To the thick paste that density is 1.15, thick paste is spray-dried under conditions of 120 DEG C of EAT, 70 DEG C of leaving air temp, obtained Extract powder;
(3) prepared by preparation:Extract powder obtained by step (2) and auxiliary material I are prepared into granule, or pulvis is prepared into auxiliary material II, Or oral liquid is prepared into auxiliary material III, it is improved pig, the preparation of chicken growth performance.
3. pig, the preparation method of the preparation of chicken growth performance are improved as claimed in claim 2, it is characterised in that described system Standby its method into granule is that auxiliary material I is added in extract powder:20 parts of sucrose, 60 parts of dextrin, stir, and add 8 parts of water, Softwood is made in 5 minutes in stirring, and softwood is crossed into 14 mesh sieves obtains wet granular, and wet granular is put into boiling drier seethe with excitement and done It is dry, EAT≤100 DEG C are controlled, the time is 15 minutes, obtains the dry particl of water content≤5%, dry particl is placed in into particle Whole grain is carried out in the mesh sieve of machine 12, pig, the granule of chicken growth performance is improved.
4. pig, the preparation method of the preparation of chicken growth performance are improved as claimed in claim 2, it is characterised in that described system Standby its method into pulvis is that auxiliary material II is added in extract powder:Starch or 80 parts of DEXTROSE ANHYDROUS, 5 parts of silica, stirring are equal It is even, picria fel tarrae pulvis is obtained, pig, the pulvis of chicken growth performance is improved.
5. pig, the preparation method of the preparation of chicken growth performance are improved as claimed in claim 2, it is characterised in that described system Standby its method into oral liquid is that 100 parts of deionized waters are added in extract powder, and heating, which is boiled to extract powder, to be completely dissolved into relatively Density is 1.05~1.07 solution, is cooled to room temperature, and it is 70% to add ethanol to concentration of alcohol, stands 48-60 hours, mistake Filter, filtrate recycling ethanol obtains the supernatant without ethanol, and auxiliary material III is added in supernatant:It is 1.5~2 parts of sodium benzoate, poly- 3~4 parts of sorb ester, adds 150~200 parts of deionized waters, stirs, through 30~50 μm of filter membrane refined filtrations, take filtrate, fills Envelope, sterilizes, and packaging is improved pig, the oral liquid of chicken growth performance.
CN201710122338.8A 2017-03-03 2017-03-03 A kind of raising pig, preparation of chicken growth performance and preparation method thereof Pending CN107050170A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929533A (en) * 2017-12-14 2018-04-20 四川农业大学 It is a kind of to promote the Chinese herbal granules into growing-finishing pigs performance, feed and preparation method thereof
CN111346218A (en) * 2018-12-24 2020-06-30 四川华德生物工程有限公司 Application of recombinant porcine interleukin 22 in preparation of medicament for improving production performance of pigs
CN112675234A (en) * 2021-02-02 2021-04-20 广西大学 Preparation for treating animal damp-heat diarrhea and dysentery, preparation method and quality detection method

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929533A (en) * 2017-12-14 2018-04-20 四川农业大学 It is a kind of to promote the Chinese herbal granules into growing-finishing pigs performance, feed and preparation method thereof
CN111346218A (en) * 2018-12-24 2020-06-30 四川华德生物工程有限公司 Application of recombinant porcine interleukin 22 in preparation of medicament for improving production performance of pigs
CN112675234A (en) * 2021-02-02 2021-04-20 广西大学 Preparation for treating animal damp-heat diarrhea and dysentery, preparation method and quality detection method

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Application publication date: 20170818