CN107048008A - A kind of feed addictive and preparation method for preventing and treating swine plague - Google Patents

A kind of feed addictive and preparation method for preventing and treating swine plague Download PDF

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Publication number
CN107048008A
CN107048008A CN201710148021.1A CN201710148021A CN107048008A CN 107048008 A CN107048008 A CN 107048008A CN 201710148021 A CN201710148021 A CN 201710148021A CN 107048008 A CN107048008 A CN 107048008A
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parts
feed addictive
added
preventing
preparation
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王炳付
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Chuzhou Flyon Agricultural Science And Technology Co Ltd
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Chuzhou Flyon Agricultural Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
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    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
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    • A61K36/904Stemonaceae (Stemona family), e.g. croomia
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention provides a kind of feed addictive and preparation method for preventing and treating swine plague, the additive includes following component:STEVIA REBAUDIANA, garlic, the root bark of tree peony, Asian puccoon, rheum officinale, radix scutellariae, the tuber of dwarf lilyturf, Snakegourd Seed, the tuber of stemona, subprostrate sophora, very little east, the capsule of weeping forsythia, radix scutellariae, balloonflower root, rheum officinale, radix glycyrrhizae;The preparation method includes:Each component is weighed to crush and be well mixed;Mixed powder is added in apparatus,Soxhlet's, ethanol is added and is heated to reflux, take out mixed powder, obtain extract solution;Mixed powder is added in flask, water is added, is flowed back, filtered while hot by ultrasonic wave added heat, washed, repeat 2 times, merging filtrate and washing lotion;Extract solution and amalgamation liquid are mixed, rotary evaporation obtains the feed addictive powder.Feed addictive of the present invention, can either play effective preventive and therapeutic effect, it is to avoid the serious financial consequences caused due to dealing with improperly to swine plague, will not allow pork chop reprimand edible again, with preferable application value and economic implications.

Description

A kind of feed addictive and preparation method for preventing and treating swine plague
Technical field
The present invention relates to agricultural breeding field of feed, in particular it relates to a kind of feed addictive for preventing and treating swine plague And preparation method.
Background technology
In recent years, developing rapidly with pig aquaculture, each boar food is also developed rapidly therewith, the pig that market occurs Hay varieties is varied, but all contains in pig feed mostly and urge long hormone so that the pig grown up is mostly in sub- strong Health state, pork quality is soft, and nutritive value is substantially reduced, in addition, some antibiotic medicines added in feed, can be in pork In remained, it is healthy to people to there is certain hidden danger.
With the raising increased with people's quality of life of population, the demand of pork constantly expands.Want to obtain meat Delicious pork, it is necessary to take care of yourself the healthy growth of pig, it is to avoid the puzzlement of various diseases, wherein swine plague can not be ignored, is passed Dye dynamics is strong, and the growth of pig can be caused to have a strong impact on, and can not only increase aquaculture cost and be also possible to produce sternly due to dealing with improperly Weight economic loss, therefore, research and development one kind can either play effective preventive and therapeutic effect to swine plague, and pork chop reprimand will not be allowed to eat again Feed addictive is significant.
The content of the invention
For defect of the prior art, it is an object of the invention to provide a kind of feed addictive and system for preventing and treating swine plague Preparation Method, can either play effective preventive and therapeutic effect, it is to avoid the serious financial consequences caused due to dealing with improperly, again to swine plague With preferable mouthfeel, pork chop reprimand will not be allowed edible, with preferable application value and economic implications.
The present invention solves technical problem and adopted the following technical scheme that:
The present invention relates to a kind of feed addictive for preventing and treating swine plague, include each component of following parts by weight:STEVIA REBAUDIANA 20 ~ 30 Part, 10 ~ 30 parts of garlic, 10 ~ 30 parts of the root bark of tree peony, 10 ~ 20 parts of Asian puccoon, 10 ~ 15 parts of rheum officinale, 10 ~ 15 parts of radix scutellariae, 10 ~ 20 parts of the tuber of dwarf lilyturf, melon 10 ~ 20 parts of beach wormwood benevolence, 5 ~ 10 parts of the tuber of stemona, 10 ~ 20 parts of subprostrate sophora, very little eastern 10 ~ 20 parts, 10 ~ 30 parts of the capsule of weeping forsythia, 5 ~ 10 parts of radix scutellariae, balloonflower root 10 ~ 20 parts, 5 ~ 15 parts of rheum officinale, 10 ~ 20 parts of radix glycyrrhizae.
Preferably, each component of following parts by weight is included:25 parts of STEVIA REBAUDIANA, 20 parts of garlic, 20 parts of the root bark of tree peony, Asian puccoon 15 Part, 12 parts of rheum officinale, 12 parts of radix scutellariae, 15 parts of the tuber of dwarf lilyturf, 15 parts of Snakegourd Seed, 8 parts of the tuber of stemona, 15 parts of subprostrate sophora, very little eastern 15 parts, the capsule of weeping forsythia 20 Part, 8 parts of radix scutellariae, 15 parts of balloonflower root, 10 parts of rheum officinale, 15 parts of radix glycyrrhizae.
The invention further relates to a kind of preparation method for the feed addictive for preventing and treating swine plague, comprise the following steps:
(1)Each traditional Chinese medicinal components are weighed respectively according to proportioning, are crushed and are well mixed, it is standby;
(2)Mixed powder filter paper parcel is added in apparatus,Soxhlet's, second is added in the flask being connected with surname extraction agent Alcohol, is heated to reflux 4 ~ 5h, takes out mixed powder, obtains extract solution;
(3)Above-mentioned mixed powder is added in flask, water is added, by ultrasonic wave added 30 ~ 60min of circumfluence distillation, mistake while hot Filter, washing;
(4)Repeat step(3)Operation 2 times, merging filtrate and washing lotion;
(5)Extract solution and amalgamation liquid are mixed, by rotary evaporation, target product feed addictive powder is obtained.
Preferably, the step(1)Particle diameter after middle crushing is 100 ~ 120 mesh.
Preferably, the step(2)The mixed powder of addition:The amount of ethanol is 10 ~ 20g:120~150mL.
Preferably, the step(2)The temperature being heated to reflux is 75 ~ 78 DEG C.
Preferably, the step(3)The quality of middle addition water is 10 ~ 20 times of mixed powder quality.
Preferably, the step(3)Middle ultrasonic wave added backflow stream temperature is 95 ~ 100 DEG C, and ultrasonic radiation is 90 ~ 100W.
Compared with prior art, the present invention has following beneficial effect:
The feed addictive and preparation method of the present invention for preventing and treating swine plague, can either play effective preventing and treating to swine plague Effect, it is to avoid the serious financial consequences caused due to dealing with improperly, and due to containing STEVIA REBAUDIANA in component so that the additive There is no the taste of the bitterness of conventional dose, with preferable mouthfeel, pork chop reprimand will not be allowed edible, with preferable application value and warp Ji meaning.
Embodiment
With reference to specific embodiment, the present invention is expanded on further.These embodiments be merely to illustrate the present invention and without In limitation the scope of the present invention.
Embodiment 1:
The present embodiment is related to a kind of feed addictive and preparation method for preventing and treating swine plague;
The additive is made up of following component:25 parts of STEVIA REBAUDIANA, 20 parts of garlic, 20 parts of the root bark of tree peony, 15 parts of Asian puccoon, 12 parts of rheum officinale, 12 parts of radix scutellariae, 15 parts of the tuber of dwarf lilyturf, 15 parts of Snakegourd Seed, 8 parts of the tuber of stemona, 15 parts of subprostrate sophora, very little eastern 15 parts, 20 parts of the capsule of weeping forsythia, 8 parts of radix scutellariae, tangerine 15 parts of stalk, 10 parts of rheum officinale, 15 parts of radix glycyrrhizae.
The preparation process of the additive is as follows:
(1)Each traditional Chinese medicinal components are weighed respectively according to proportioning, and powder particle diameter is 100 ~ 120 mesh, and is well mixed, standby;
(2)Mixed powder filter paper parcel is added in apparatus,Soxhlet's, second is added in the flask being connected with surname extraction agent Alcohol, mixed powder:The amount of ethanol is 10g:120mL, 4h is heated to reflux in 78 DEG C, is taken out mixed powder, is obtained extract solution;
(3)Above-mentioned mixed powder is added in flask, 15 times of water of mixture quality is added, in 95 DEG C, ultrasonic radiation is 90W Under the conditions of by ultrasonic wave added circumfluence distillation 50min, filter while hot, wash;
(4)Repeat step(3)Operation 2 times, merging filtrate and washing lotion;
(5)Extract solution and amalgamation liquid are mixed, by rotary evaporation, target product feed addictive powder is obtained.
The additive that the present embodiment is prepared is added among pig feed, and wherein additive is with quality of the fodder ratio 1:100 ~ 150, preferable preventive and therapeutic effect is played to swine plague, guarantee, swine plague preventing and treating are provided for the healthy growth of pig Rate reaches 92.9%.
Embodiment 2:
The present embodiment is related to a kind of feed addictive and preparation method for preventing and treating swine plague;
The additive is made up of following component:20 parts of STEVIA REBAUDIANA, 10 parts of garlic, 10 parts of the root bark of tree peony, 10 parts of Asian puccoon, 10 parts of rheum officinale, 10 parts of radix scutellariae, 10 parts of the tuber of dwarf lilyturf, 10 parts of Snakegourd Seed, 5 parts of the tuber of stemona, 10 parts of subprostrate sophora, very little eastern 10 parts, 10 parts of the capsule of weeping forsythia, 5 parts of radix scutellariae, tangerine 10 parts of stalk, 5 parts of rheum officinale, 10 parts of radix glycyrrhizae.
The preparation process of the additive is as follows:
(1)Each traditional Chinese medicinal components are weighed respectively according to proportioning, and powder particle diameter is 100 ~ 120 mesh, and is well mixed, standby;
(2)Mixed powder filter paper parcel is added in apparatus,Soxhlet's, second is added in the flask being connected with surname extraction agent Alcohol, mixed powder:The amount of ethanol is 10g:120mL, 4h is heated to reflux in 78 DEG C, is taken out mixed powder, is obtained extract solution;
(3)Above-mentioned mixed powder is added in flask, 10 times of water of mixture quality is added, in 95 DEG C, ultrasonic radiation is 90W Under the conditions of by ultrasonic wave added circumfluence distillation 30min, filter while hot, wash;
(4)Repeat step(3)Operation 2 times, merging filtrate and washing lotion;
(5)Extract solution and amalgamation liquid are mixed, by rotary evaporation, target product feed addictive powder is obtained.
The additive that the present embodiment is prepared is added among pig feed, and wherein additive is with quality of the fodder ratio 1:100 ~ 150, preferable preventive and therapeutic effect is played to swine plague, guarantee, swine plague preventing and treating are provided for the healthy growth of pig Rate reaches 91.6%.
Embodiment 3:
The present embodiment is related to a kind of feed addictive and preparation method for preventing and treating swine plague;
The additive is made up of following component:30 parts of STEVIA REBAUDIANA, 30 parts of garlic, 30 parts of the root bark of tree peony, 20 parts of Asian puccoon, 15 parts of rheum officinale, 15 parts of radix scutellariae, 20 parts of the tuber of dwarf lilyturf, 20 parts of Snakegourd Seed, 10 parts of the tuber of stemona, 20 parts of subprostrate sophora, very little eastern 20 parts, 30 parts of the capsule of weeping forsythia, 10 parts of radix scutellariae, 20 parts of balloonflower root, 15 parts of rheum officinale, 20 parts of radix glycyrrhizae.
The preparation process of the additive is as follows:
(1)Each traditional Chinese medicinal components are weighed respectively according to proportioning, and powder particle diameter is 100 ~ 120 mesh, and is well mixed, standby;
(2)Mixed powder filter paper parcel is added in apparatus,Soxhlet's, second is added in the flask being connected with surname extraction agent Alcohol, mixed powder:The amount of ethanol is 20g:150mL, 5h is heated to reflux in 75 DEG C, is taken out mixed powder, is obtained extract solution;
(3)Above-mentioned mixed powder is added in flask, 20 times of water of mixture quality is added, in 100 DEG C, ultrasonic radiation is By ultrasonic wave added circumfluence distillation 60min under the conditions of 100W, filter, wash while hot;
(4)Repeat step(3)Operation 2 times, merging filtrate and washing lotion;
(5)Extract solution and amalgamation liquid are mixed, by rotary evaporation, target product feed addictive powder is obtained.
The additive that the present embodiment is prepared is added among pig feed, and wherein additive is with quality of the fodder ratio 1:100 ~ 150, preferable preventive and therapeutic effect is played to swine plague, guarantee, swine plague preventing and treating are provided for the healthy growth of pig Rate reaches 92.6%.
The feed addictive and preparation method of the present invention for preventing and treating swine plague, can either be played effectively to swine plague Preventive and therapeutic effect, it is to avoid the serious financial consequences caused due to dealing with improperly, and due to containing STEVIA REBAUDIANA in component so that it is described to add Plus agent does not have the taste of the bitterness of conventional dose, with preferable mouthfeel, pork chop reprimand will not be allowed edible, with preferable application value And economic implications.
The specific embodiment of the present invention is described above.It is to be appreciated that the invention is not limited in above-mentioned Particular implementation, those skilled in the art can make various deformations or amendments within the scope of the claims, this not shadow Ring the substantive content of the present invention.

Claims (8)

1. a kind of feed addictive for preventing and treating swine plague, it is characterised in that:Include each component of following parts by weight:STEVIA REBAUDIANA 20 ~ 30 parts, 10 ~ 30 parts of garlic, 10 ~ 30 parts of the root bark of tree peony, 10 ~ 20 parts of Asian puccoon, 10 ~ 15 parts of rheum officinale, 10 ~ 15 parts of radix scutellariae, the tuber of dwarf lilyturf 10 ~ 20 Part, 10 ~ 20 parts of Snakegourd Seed, 5 ~ 10 parts of the tuber of stemona, 10 ~ 20 parts of subprostrate sophora, very little eastern 10 ~ 20 parts, 10 ~ 30 parts of the capsule of weeping forsythia, 5 ~ 10 parts of radix scutellariae, 10 ~ 20 parts of balloonflower root, 5 ~ 15 parts of rheum officinale, 10 ~ 20 parts of radix glycyrrhizae.
2. the feed addictive according to claim 1 for preventing and treating swine plague, it is characterised in that:Including following parts by weight Each component:25 parts of STEVIA REBAUDIANA, 20 parts of garlic, 20 parts of the root bark of tree peony, 15 parts of Asian puccoon, 12 parts of rheum officinale, 12 parts of radix scutellariae, 15 parts of the tuber of dwarf lilyturf, Snakegourd Fruit 15 parts of benevolence, 8 parts of the tuber of stemona, 15 parts of subprostrate sophora, very little eastern 15 parts, 20 parts of the capsule of weeping forsythia, 8 parts of radix scutellariae, 15 parts of balloonflower root, 10 parts of rheum officinale, radix glycyrrhizae 15 Part.
3. a kind of preparation method of the feed addictive according to claim 1 or 2 for preventing and treating swine plague, it is characterised in that: Comprise the following steps:
(1)Each traditional Chinese medicinal components are weighed respectively according to proportioning, are crushed and are well mixed, it is standby;
(2)Mixed powder filter paper parcel is added in apparatus,Soxhlet's, second is added in the flask being connected with surname extraction agent Alcohol, is heated to reflux 4 ~ 5h, takes out mixed powder, obtains extract solution;
(3)Above-mentioned mixed powder is added in flask, water is added, by ultrasonic wave added 30 ~ 60min of circumfluence distillation, mistake while hot Filter, washing;
(4)Repeat step(3)Operation 2 times, merging filtrate and washing lotion;
(5)Extract solution and amalgamation liquid are mixed, by rotary evaporation, target product feed addictive powder is obtained.
4. the preparation method of the feed addictive according to claim 3 for preventing and treating swine plague, it is characterised in that:The step (1)Particle diameter after middle crushing is 100 ~ 120 mesh.
5. the preparation method of the feed addictive according to claim 3 for preventing and treating swine plague, it is characterised in that:The step (2)The mixed powder of addition:The amount of ethanol is 10 ~ 20g:120~150mL.
6. the preparation method of the feed addictive according to claim 3 for preventing and treating swine plague, it is characterised in that:The step (2)The temperature being heated to reflux is 75 ~ 78 DEG C.
7. the preparation method of the feed addictive according to claim 3 for preventing and treating swine plague, it is characterised in that:The step (3)The quality of middle addition water is 10 ~ 20 times of mixed powder quality.
8. the preparation method of the feed addictive according to claim 3 for preventing and treating swine plague, it is characterised in that:The step (3)Middle ultrasonic wave added backflow stream temperature is 95 ~ 100 DEG C, and ultrasonic radiation is 90 ~ 100W.
CN201710148021.1A 2017-03-14 2017-03-14 A kind of feed addictive and preparation method for preventing and treating swine plague Withdrawn CN107048008A (en)

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Application publication date: 20170818