CN107002094A - 用于治疗潜伏病毒感染的组合物和方法 - Google Patents
用于治疗潜伏病毒感染的组合物和方法 Download PDFInfo
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- CN107002094A CN107002094A CN201580028992.1A CN201580028992A CN107002094A CN 107002094 A CN107002094 A CN 107002094A CN 201580028992 A CN201580028992 A CN 201580028992A CN 107002094 A CN107002094 A CN 107002094A
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462005395P | 2014-05-30 | 2014-05-30 | |
| US62/005,395 | 2014-05-30 | ||
| US201462029072P | 2014-07-25 | 2014-07-25 | |
| US62/029,072 | 2014-07-25 | ||
| PCT/US2015/033180 WO2015184259A1 (en) | 2014-05-30 | 2015-05-29 | Compositions and methods to treat latent viral infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107002094A true CN107002094A (zh) | 2017-08-01 |
Family
ID=53366336
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580028992.1A Pending CN107002094A (zh) | 2014-05-30 | 2015-05-29 | 用于治疗潜伏病毒感染的组合物和方法 |
| CN201580029041.6A Pending CN106574256A (zh) | 2014-05-30 | 2015-05-29 | 用于潜伏病毒感染的递送治疗的组合物和方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580029041.6A Pending CN106574256A (zh) | 2014-05-30 | 2015-05-29 | 用于潜伏病毒感染的递送治疗的组合物和方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (7) | US20160060655A1 (enExample) |
| EP (3) | EP3149169A1 (enExample) |
| JP (3) | JP2017518075A (enExample) |
| KR (1) | KR20170005494A (enExample) |
| CN (2) | CN107002094A (enExample) |
| AU (3) | AU2015266776A1 (enExample) |
| BR (1) | BR112016028023A2 (enExample) |
| CA (2) | CA2949713A1 (enExample) |
| SG (1) | SG11201610028TA (enExample) |
| WO (3) | WO2015184262A1 (enExample) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3613852A3 (en) | 2011-07-22 | 2020-04-22 | President and Fellows of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| CN113005148A (zh) | 2013-01-16 | 2021-06-22 | 爱默蕾大学 | Cas9-核酸复合物及其相关用途 |
| MX369747B (es) | 2013-04-16 | 2019-11-20 | Regeneron Pharma | Modificación dirigida del genoma de rata. |
| US20150044192A1 (en) | 2013-08-09 | 2015-02-12 | President And Fellows Of Harvard College | Methods for identifying a target site of a cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9925248B2 (en) | 2013-08-29 | 2018-03-27 | Temple University Of The Commonwealth System Of Higher Education | Methods and compositions for RNA-guided treatment of HIV infection |
| US9737604B2 (en) | 2013-09-06 | 2017-08-22 | President And Fellows Of Harvard College | Use of cationic lipids to deliver CAS9 |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| RU2685914C1 (ru) | 2013-12-11 | 2019-04-23 | Регенерон Фармасьютикалс, Инк. | Способы и композиции для направленной модификации генома |
| US11053481B2 (en) | 2013-12-12 | 2021-07-06 | President And Fellows Of Harvard College | Fusions of Cas9 domains and nucleic acid-editing domains |
| AU2015266776A1 (en) | 2014-05-30 | 2016-12-08 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods of delivering treatments for latent viral infections |
| AU2015298571B2 (en) | 2014-07-30 | 2020-09-03 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| RU2734770C2 (ru) | 2014-11-21 | 2020-10-23 | Регенерон Фармасьютикалз, Инк. | Способы и композиции для нацеленной генетической модификации с использованием парных гидовых рнк |
| AU2015355546B2 (en) | 2014-12-03 | 2021-10-14 | Agilent Technologies, Inc. | Guide RNA with chemical modifications |
| US10059940B2 (en) * | 2015-01-27 | 2018-08-28 | Minghong Zhong | Chemically ligated RNAs for CRISPR/Cas9-lgRNA complexes as antiviral therapeutic agents |
| WO2016164356A1 (en) | 2015-04-06 | 2016-10-13 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically modified guide rnas for crispr/cas-mediated gene regulation |
| US20160346362A1 (en) * | 2015-05-29 | 2016-12-01 | Agenovir Corporation | Methods and compositions for treating cytomegalovirus infections |
| WO2016196282A1 (en) * | 2015-05-29 | 2016-12-08 | Agenovir Corporation | Compositions and methods for cell targeted hpv treatment |
| WO2016196308A1 (en) * | 2015-05-29 | 2016-12-08 | Agenovir Corporation | Methods and compositions for treating cells for transplant |
| US10117911B2 (en) | 2015-05-29 | 2018-11-06 | Agenovir Corporation | Compositions and methods to treat herpes simplex virus infections |
| WO2017058793A1 (en) * | 2015-09-29 | 2017-04-06 | Agenovir Corporation | Delivery methods and compositions |
| WO2017068077A1 (en) | 2015-10-20 | 2017-04-27 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methods and products for genetic engineering |
| US12043852B2 (en) | 2015-10-23 | 2024-07-23 | President And Fellows Of Harvard College | Evolved Cas9 proteins for gene editing |
| JP2019508364A (ja) | 2015-12-09 | 2019-03-28 | エクシジョン バイオセラピューティクス インコーポレイテッド | 免疫抑制療法中のjcウイルス活性化およびpml(進行性多巣性白質脳症)のリスクを除去するための遺伝子編集方法および組成物 |
| JP2019512458A (ja) * | 2016-01-25 | 2019-05-16 | エクシジョン バイオセラピューティクス インコーポレイテッド | Rnaによって誘導された、ヒトjcウイルス及び他のポリオーマウイルスの根絶 |
| US20190032057A1 (en) * | 2016-01-25 | 2019-01-31 | Excision Biotherapeutics, Inc. | Methods and compositions for rna-guided treatment of hiv infection |
| US20170246260A1 (en) * | 2016-02-25 | 2017-08-31 | Agenovir Corporation | Modified antiviral nuclease |
| CA3015353A1 (en) * | 2016-02-25 | 2017-08-31 | Agenovir Corporation | Viral and oncoviral nuclease treatment |
| WO2017189964A2 (en) | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| WO2017189959A1 (en) | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| WO2017192172A1 (en) * | 2016-05-05 | 2017-11-09 | Temple University - Of The Commonwealth System Of Higher Education | Rna guided eradication of varicella zoster virus |
| US20190225956A1 (en) * | 2016-05-10 | 2019-07-25 | United States Government As Represented By The Department Of Veterans Affairs | Lentiviral delivery of crispr/cas constructs that cleave genes essential for hiv-1 infection and replication |
| EP4368637A3 (en) | 2016-05-20 | 2024-07-10 | Regeneron Pharmaceuticals, Inc. | Methods for breaking immunological tolerance using multiple guide rnas |
| WO2017210380A1 (en) * | 2016-06-01 | 2017-12-07 | Excision Biotherapeutics, Inc. | Compositions and methods of treatment for lytic and lysogenic viruses |
| US10767175B2 (en) | 2016-06-08 | 2020-09-08 | Agilent Technologies, Inc. | High specificity genome editing using chemically modified guide RNAs |
| EP3468356A4 (en) * | 2016-06-14 | 2020-02-26 | Regents Of The University Of Minnesota | GENETICALLY MODIFIED CELLS, TISSUES AND ORGANS FOR THE TREATMENT OF A DISEASE |
| GB2568182A (en) | 2016-08-03 | 2019-05-08 | Harvard College | Adenosine nucleobase editors and uses thereof |
| WO2018031683A1 (en) | 2016-08-09 | 2018-02-15 | President And Fellows Of Harvard College | Programmable cas9-recombinase fusion proteins and uses thereof |
| US11542509B2 (en) | 2016-08-24 | 2023-01-03 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| US11801374B2 (en) * | 2016-09-02 | 2023-10-31 | The General Hospital Corporation | Methods and systems for non-contact construction of an internal structure |
| GB2573062A (en) | 2016-10-14 | 2019-10-23 | Harvard College | AAV delivery of nucleobase editors |
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Application publication date: 20170801 |