CN1069737A - 胰岛素类似物 - Google Patents

胰岛素类似物 Download PDF

Info

Publication number
CN1069737A
CN1069737A CN92105888A CN92105888A CN1069737A CN 1069737 A CN1069737 A CN 1069737A CN 92105888 A CN92105888 A CN 92105888A CN 92105888 A CN92105888 A CN 92105888A CN 1069737 A CN1069737 A CN 1069737A
Authority
CN
China
Prior art keywords
asp
seq
des
insulin
xaa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN92105888A
Other languages
English (en)
Chinese (zh)
Inventor
D·N·布雷姆斯
R·E·钱斯
B·H·弗兰克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of CN1069737A publication Critical patent/CN1069737A/zh
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN92105888A 1991-06-21 1992-06-19 胰岛素类似物 Pending CN1069737A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US718,574 1985-04-01
US71857491A 1991-06-21 1991-06-21

Publications (1)

Publication Number Publication Date
CN1069737A true CN1069737A (zh) 1993-03-10

Family

ID=24886590

Family Applications (1)

Application Number Title Priority Date Filing Date
CN92105888A Pending CN1069737A (zh) 1991-06-21 1992-06-19 胰岛素类似物

Country Status (17)

Country Link
EP (1) EP0519750A3 (cg-RX-API-DMAC10.html)
JP (1) JPH05271283A (cg-RX-API-DMAC10.html)
CN (1) CN1069737A (cg-RX-API-DMAC10.html)
AU (1) AU1837792A (cg-RX-API-DMAC10.html)
BR (1) BR9202322A (cg-RX-API-DMAC10.html)
CA (1) CA2071382A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ186492A3 (cg-RX-API-DMAC10.html)
FI (1) FI922882L (cg-RX-API-DMAC10.html)
HU (1) HUT61581A (cg-RX-API-DMAC10.html)
IE (1) IE921997A1 (cg-RX-API-DMAC10.html)
IL (1) IL102240A0 (cg-RX-API-DMAC10.html)
MX (1) MX9202987A (cg-RX-API-DMAC10.html)
NO (1) NO922376L (cg-RX-API-DMAC10.html)
NZ (1) NZ243229A (cg-RX-API-DMAC10.html)
TW (1) TW222643B (cg-RX-API-DMAC10.html)
YU (1) YU64192A (cg-RX-API-DMAC10.html)
ZA (1) ZA924448B (cg-RX-API-DMAC10.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ158895A3 (en) * 1992-12-18 1995-12-13 Lilly Co Eli Insulin analog, process of its preparation and pharmaceutical composition containing thereof
US20020111461A1 (en) 1999-05-21 2002-08-15 Todd C. Somers Low molecular weight peptidomimetic growth hormone secretagogues
DK1265630T3 (da) 2000-03-24 2006-10-09 Genentech Inc Anvendelse af insulin til behandling af brusksygdomme
JPWO2006093222A1 (ja) * 2005-03-02 2008-08-07 味の素株式会社 インスリンの多量体形成阻害剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
AU612141B2 (en) * 1987-02-25 1991-07-04 Novo Nordisk A/S Novel insulin derivatives
US4992418A (en) * 1987-07-17 1991-02-12 Mount Sinai School Of Medicine Superactive human insulin analogue-[10-Aspartic Acid-B]Human Insulin
IL93282A (en) * 1989-02-09 1995-08-31 Lilly Co Eli Insulin analogues

Also Published As

Publication number Publication date
AU1837792A (en) 1992-12-24
HUT61581A (en) 1993-01-28
JPH05271283A (ja) 1993-10-19
IE921997A1 (en) 1992-12-30
YU64192A (sh) 1994-06-10
MX9202987A (es) 1993-01-01
HU9202048D0 (en) 1992-09-28
NO922376L (no) 1992-12-22
FI922882A0 (fi) 1992-06-18
IL102240A0 (en) 1993-01-14
FI922882A7 (fi) 1992-12-22
TW222643B (cg-RX-API-DMAC10.html) 1994-04-21
EP0519750A2 (en) 1992-12-23
ZA924448B (en) 1993-12-17
EP0519750A3 (en) 1993-06-23
CZ186492A3 (en) 1993-01-13
FI922882L (fi) 1992-12-22
CA2071382A1 (en) 1992-12-22
BR9202322A (pt) 1993-01-19
NO922376D0 (no) 1992-06-17
NZ243229A (en) 1994-09-27

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication