CN106955294A - It is a kind of that there is active mycelium group compound for the treatment of breast cancer and preparation method thereof - Google Patents
It is a kind of that there is active mycelium group compound for the treatment of breast cancer and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
- A61K36/068—Cordyceps
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
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- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
Abstract
The present invention relates to a kind of active mycelium group compound for having and treating breast cancer, the preparation method of the active mycelium group compound is further related to.By weight percentage by Poria mycelium 25~30%, armillaria mycelium 20~24%, shiitake mushroom hypha 5~7%, the, of shaggy mane mycelium body 5~7% Auricularia mycelium 4~6%, high-quality green tea mushroom mycelium 4~6%, Wild Ganoderma mycelium 4~6%, maitake mushroom mycelia 4~6%, aweto mycelium 3~5%, tricholoma matsutake mycelium 3~5%, prepared from coriolus versicolor mycelium 3~5%, hericium mycelium 3~5% constitute.Product Green of the present invention, safe and healthy, the effect with treatment breast cancer, available for patient with breast cancer.
Description
Technical field
The present invention relates to a kind of active mycelium group compound for having and treating breast cancer, active mycelium group conjunction is further related to
The preparation method of thing.
Background technology
Women is due to reasons such as the physilogical characteristics of itself, the demand with some special health cares.Female patient is unique
And diversified pharmaceutical requirements determine the latency development prospect of the pharmaceutical market related to women.
In recent years, the incidence of disease sharp increase of breast cancer.In western countries, it is No.1 dead former that breast cancer has turned into women
Cause.And China was in recent years, breast cancer incidence is also in continuous rise.In the large size city of China, breast cancer incidence
Also first or No. second tumor disease of women is turned into, and in vast rural area, breast cancer still comes the 9th of tumor disease
Position.Breast cancer is " beautiful killer ", because it is not only destroyed, women is most beautiful, " secondary sex characters " that also most deserves pride,
More importantly, the women after mastectomy no matter physiology or psychology overwhelm greatly, many women often therefore lose
Lose life confidence.
The positive one kind that lacks can treat breast cancer, have no toxic side effect at present, and without any steroids additive, it is pure green
The natural bioactivity mycelia polyose of color.The natural bioactivity mycelia polyose of these new pure greens is expected into
For the growth bright spot for the treatment of breast cancer in the market newly.Because breast cancer is still a kind of primary tumor of serious threat WomanHealth
Disease, it is contemplated that there is great demand amount in its market for the natural bioactivity mycelia polyose of this kind of pure green.
The content of the invention
The purpose of the present invention is to overcome the deficiencies in the prior art to be had no toxic side effect there is provided one kind, and one kind has treatment mammary gland
The active mycelium group compound of cancer.It is a further object of the present invention to provide a kind of preparation method of the active mycelium group compound.
The present invention is a kind of to have the active mycelium group compound for treating breast cancer, by weight percentage by Poria mycelium 25
~30%, armillaria mycelium 20~24%, shiitake mushroom hypha 5~7%, the, of shaggy mane mycelium body 5~7% Auricularia mycelium 4~
6%th, high-quality green tea mushroom mycelium 4~6%, Wild Ganoderma mycelium 4~6%, maitake mushroom mycelia 4~6%, aweto mycelium 3~5%,
Tricholoma matsutake mycelium 3~5%, prepared from coriolus versicolor mycelium 3~5%, hericium mycelium 3~5% are constituted.
By weight percentage, preferred scheme of the invention, by Poria mycelium 26~31%, armillaria mycelium 20~
24%th, shiitake mushroom hypha 6~8%, the, of shaggy mane mycelium body 6~8% Auricularia mycelium 4~6%, high-quality green tea mushroom mycelium 4~6%, wild
Ganoderma lucidum mycelium 4~6%, maitake mushroom mycelia 4~6%, aweto mycelium 3~5%, tricholoma matsutake mycelium 3~5%, manyzoned polypore bacteria
Filament 3~5%, hericium mycelium 3~5% are constituted.
By weight percentage, most preferably scheme of the invention, by Poria mycelium 30%, armillaria mycelium 20%, mushroom
Mycelium 7%, the, of shaggy mane mycelium body 7% Auricularia mycelium 5%, high-quality green tea mushroom mycelium 5%, Wild Ganoderma mycelium 5%, Grifolas frondosa germ
Filament 5%, aweto mycelium 4%, tricholoma matsutake mycelium 4%, prepared from coriolus versicolor mycelium 4%, hericium mycelium 4% are constituted.
A kind of above-described active mycelium group compound with treatment breast cancer, can be made into any pharmacy
Described formulation.
A kind of above-described active mycelium group compound with treatment breast cancer, formulation preferably is pill, capsule
Or vina.
A kind of preparation method with the active mycelium group compound for treating breast cancer is as follows：
1st, the preparation method of Poria mycelium：Wild Poria cocos passes through tissue and separates, cultivates, extracts, concentrates, freezes, is dried in vacuo,
Obtain Poria mycelium；
2nd, the preparation method of armillaria mycelium：Halimasch passes through tissue and separates, cultivates, extracts, concentrates, freezes, is dried in vacuo,
Obtain armillaria mycelium；
3rd, the preparation method of shiitake mushroom hypha：Wild-type champignon passes through tissue and separates, cultivates, extracts, concentrates, freezes, is dried in vacuo,
Obtain shiitake mushroom hypha；
4th, the preparation method of shaggy mane mycelium body：Wild coprinus comatus is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain shaggy mane mycelium body；
5th, the preparation method of agaric mycelium：Wild black fungus is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain agaric mycelium；
6th, the mycelial preparation method of high-quality green tea mushroom：Wild high-quality green tea mushroom bacterium passes through tissue and separates, cultivates, extracting, concentrating, freezing, very
Sky is dried, and obtains high-quality green tea mushroom mycelium；
7th, the mycelial preparation method of Wild Ganoderma：Wild Ganoderma passes through tissue and separates, cultivates, extracts, concentrates, freezes, is dried in vacuo,
Obtain Wild Ganoderma mycelium；
8th, the preparation method of maitake mushroom mycelia：Wild Grifola frondosa is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain maitake mushroom mycelia；
9th, the preparation method of aweto mycelium：Wild cordyceps by tissue separation, culture, extract, concentration, it is lyophilized,
Vacuum drying, obtains aweto mycelium；
10th, the preparation method of tricholoma matsutake mycelium：Wild matsutake is done by tissue separation, culture, extraction, concentration, lyophilized, vacuum
It is dry, obtain tricholoma matsutake mycelium；
11st, the preparation method of prepared from coriolus versicolor mycelium：Wild rainbow conk is done by tissue separation, culture, extraction, concentration, lyophilized, vacuum
It is dry, obtain prepared from coriolus versicolor mycelium；
12nd, the preparation method of hericium mycelium：Wild Hericium erinaceus is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain hericium mycelium；
13rd, by Poria mycelium obtained above, armillaria mycelium, shiitake mushroom hypha, shaggy mane mycelium Ti, fungus mycelium
Body, high-quality green tea mushroom mycelium, Wild Ganoderma mycelium, maitake mushroom mycelia, aweto mycelium, tricholoma matsutake mycelium, rainbow conk mycelia
Body, hericium mycelium are crushed, are milled respectively, mix in proportion, and cross the sieve of 300 mesh, 300 purposes are made thin
The sterilized fine powder handled well, is loaded capsule by powder, and a kind of active mycelium group compound for having and treating breast cancer is just made
Capsule；
The sterilized pulvis handled well is made pellet, dried, whole grain, just be made it is a kind of have treatment breast cancer active bacteria
The granule of silk group compound（Electuary）；
The sterilized pulvis handled well is loaded the screen pack of 300 mesh, then immerse in 60 degree of pure grain daqu fermentation wine and carry out 6
To the secondary fermentation of 12 months, by allotment, filtering, a kind of active mycelium group compound with treatment breast cancer is just made
Vina.
A kind of active mycelium group compound selection Poria mycelium with treatment breast cancer of the present invention, halimasch mycelia
Body, shiitake mushroom hypha, shaggy mane mycelium body, Auricularia myceliums, high-quality green tea mushroom mycelium, Wild Ganoderma mycelium, grifola frondosus mycelia
Body, aweto mycelium, tricholoma matsutake mycelium, prepared from coriolus versicolor mycelium, hericium mycelium are combined so that various mycelium work(
Effect produces synergy, so as to reach the purpose for the treatment of breast cancer.Various mycelium main components and effect：
Poria mycelium contains the materials such as pachyman, pachymic acid, aliphatic acid, lecithin, adenine, protease and triterpenes,
Also containing mineral matters such as potassium, calcium, magnesium, phosphorus, iron, sulphur and silica.Its primary efficacy:
1st, antibacterial action：100% decoction of Poria cocos burrows method with flat board to staphylococcus aureus, Escherichia coli, proteus etc.
There is inhibitory action.
2nd, to the influence of digestive system：Poria cocos has direct relexation to family's rabbits infestines, to rat pylorus ligation institute
The ulcer of formation has preventive effect, and can drop hydrochloric acid in gastric juice.Separately there is significant protective effect to Liver Damage in Rats caused by CCl4, make paddy third
Transaminase activity is substantially reduced, and prevents necrosis of liver cells.
3rd, blood glucose is reduced：Poria cocos can reduce blood glucose, for hyperglycaemia personage, and Poria cocos has certain therapeutic action.
4th, to action of the heart：The traditional Chinese medical science thinks, Poria cocos can be used for palpitaition, the disease such as insomnia.Poria cocos energy mental-tranquilization, thus it is available
In diseases such as confused and worried, palpitaition, insomnias.Experiment also indicates that tincture, preserved material can suppress toad isolated heart, and ether or ethanol are carried
Taking thing can then make the heart shrink reinforcement.
5th, antitumor action：Pachymaran body presents strong antitumor action in animal experiment.Poria cocos has anti-
Atrophy of thymus gland and the increase of anti-spleen and the function of suppressing tumour growth.
6th, to the influence of immunologic function
(1) cytotoxic effect of macrophage is increased.
(2) methylol pachymaran can be remarkably reinforced mouse serum complement number and special antigen-binding cells
Number.
(3) nonspecific acid esterase positive lymphocyte number is increased.
(4) cytotoxicity of T lymphocytes is strengthened.
7th, to the influence of hematological system：Poria cocos enables to Neuroleptic Leukocytopenia to accelerate rise, and in vitro Healthy People can be made red thin
Born of the same parents rise about 25%, and can effectively delay the exhaustion of haemocyte in incubation period.Experiment shows that Poria cocos can make mice plasma skin
Matter ketone is significantly raised.
8th, the influence of Central nervous system：Poria cocos decoction has sedation.The synergy of Poria cocos and yellow Jackets.
Poria cocos decoction (10g/kg) fails to be obviously prolonged the anesthesia duration of yellow Jackets.
9th, anticancer：Poria cocos has certain antitumaous effect.The conventional treatment cancer of the esophagus of clinic, stomach cancer, liver cancer, nasopharyngeal carcinoma, tongue cancer,
Belong in the carcinomas such as breast cancer, carcinoma of urinary bladder, lung cancer, exedens melanoma the insufficiency of the spleen with overabundance of dampness, stop in phlegm and retained fluid, damp and hot heap soil or fertilizer over and around the roots knot person.
10th, air making-up and spleen enlivening：The traditional Chinese medical science thinks that Poria cocos can be used for splenasthenic diarrhea.Poria cocos can invigorating the spleen, and can excreting dampness, for spleen
Diarrhea caused by empty dysfunction of the spleen in transportation and transformation, under band, there is the effect of giving consideration to both the incidental and fundamental using Poria cocos, often with the compatibility such as Radix Codonopsis, the bighead atractylodes rhizome, Chinese yam.Again may be used
With for tonifying lung spleen, the adjuvant of the deficiency of vital energy is controlled.
11st, phlegm is controlled：Poria cocos is used for phlegmatic cough, and phlegm wet enters network, aching pain in shoulder and back.Poria cocos is unable to transmitting and distributing the fluids for insufficiency of the spleen,
Stop the disease that phlegm and retained fluid is given birth in dimerization, with therapeutic action.The tuber of pinellia, dried orange peel can be used with using, also can be with cassia twig, the bighead atractylodes rhizome with use.Phlegm wet is controlled to enter
Network, aching shoulder and back, can be with the tuber of pinellia, Fructus Aurantii with use.
Armillaria mycelium is more up to every milli of hectogram more than 2000 rich in the trace elements such as a large amount of calcium, phosphorus, iron, the content of potassium
Gram.In addition the nutrition such as protein, carrotene, vitamin C, is more than ten times of general vegetables, is classified as by some developed countries
One based food.Its primary efficacy is：
（1）Strengthen body immunity, the effect such as intelligence development is happy, QI invigorating is not hungry, macrobiosis is made light of one's life by commiting suicide.（2）To weak, empty after being ill thin, easy
Hungry people has takes a tonic or nourishing food to build up one's health effect well.
（3）Can effectively anti-aging, treatment of vascular hardening, the effect for skin of moistening.
（4）Oophoroma and breast cancer and some other cancer can be treated, the lifetime of patient can be extended.（5）Have
Effect of appetizing, abundant cellulose also has the aid digestion and anti-effect treated constipation.
（6）Effect with reduction cholesterol, it is to avoid harm of the saturated fatty acid to body in meat, can be effectively
Prevent the generation of cardiovascular and cerebrovascular disease.
Shiitake mushroom hypha contains antineoplastic component --- the lentinan that a kind of molecular weight is 1,000,000, contains reduction blood fat
Composition --- Eritadenine, the derivative of mushroom adenine also contains antiviral ingredients --- the inducing agent of interferon：Double-strand
Ribosomal ribonucleic acid, protein 18.64%, fat 4.8%, carbohydrate 71%, isoleucine, phenylalanine, methionine, threonine, figured silk fabrics
7 kinds of necessary amino acid of human body such as propylhomoserin, also containing the substantial amounts of black alcohol of the ergot for changing vitamin D and the black alcohol of bacterium, B1, B2,
PP and mineral salt and crude fibre, calcium, phosphorus, iron, niacin, solubility are without ammoniacal substance etc..Primary efficacy：
（1）Reducing blood lipid, hypotensive, antithrombotic, it is hypoglycemic, feel at ease to calm the nerves, palpitaition, insomnia, support spirit, peace soul, infantile convulsion,
Trusted subordinate's turgor, cerebrum tonifying nourishing the bone marrow.
（2）Retention of water-damp, difficult urination, oedema, strengthening spleen and middle warmer QI invigorating be not hungry.To venereal disease, syphilis, AIDS, blister sore
Poison, helicobacter pylori, control wind blood-breaking, bladder damp-heat, Escherichia coli.
（3）Antiviral, anti-flu, cough-relieving, resolving sputum, relieving asthma, streptococcus pneumonia, spore coccus have inhibitory action, control knot
The generation of core disease.
（4）Invigorating the spleen is aid digestion：Poor appetite, in poor health, abnormal, constipation of defecating.Appetizing preventing or arresting vomiting, bitter taste tongue are done；By
Hot-water heating spleen, rule QI invigorating, flat fiery antidiarrheal are made, also there is certain benefit to hepatosplenomegaly.
（5）There is good tune due to a lack of rickets caused by serium inorganic phosphorus, blood calcium dysbolism caused by vitamin D to infant
Section is acted on.
（6）To skin disease, leukaemia, endocrinopathy, quickly increase immunologic function, calcium is acted on very well.
（7）There are filling liver kidney, strengthening the spleen and stomach, replenishing qi and blood, intelligence promoting and tranquilization, caring skin.
（8）There is strong inhibitory action to cancer cell：Colon cancer, lung cancer, breast cancer.Advanced cancer long-term taking this product exists
The chemotherapy time improves patient's immunologic function, improves curative effect, extension life cycle.
Shaggy mane mycelium body contains the trace elements such as protein, polysaccharide, fat, crude fibre, ashes, calcium, iron, vitamin
B1, B2,8 kinds of necessary amino acid of human body etc..Primary efficacy：
（1）Hypotensive, hypoglycemic, reducing blood lipid, the content of reduction serum cholesterol, prevention of arterial hardening, heart disease and obesity
Generation.
（2）Blood sugar concentration is reduced, largely takes for a long time and diabetic is had clear improvement.
（3）Clear god's intelligence development, strengthening the spleen and stomach, aid digestion, defaecation, the serial stomach trouble of helicobacter pylori can repair impaired mucous membrane.
（4）Antitumor, anticancer, anti-cancer have auxiliary treatment.
（5）There is certain inhibitory action to Escherichia coli, golden yellow grape bacillus, hay bacillus.
（6）There is good adjustment effect to various chronic diseases and hypoimmunity, be to adjust one of endocrinopathy not
Alternative health products.
（7）To the patient with hemorrhoid after taking a period of time, it can be improved well.
（8）Accelerate the detoxification ability of liver, enteron aisle bone toxic waste can be removed in vitro.
Agaric mycelium contains the black alcohol of polysaccharide, ergot, vitamin B2, adustin, amino acid, protein, lipid, Hu
Other trace elements such as radish element, potassium, sodium, calcium, magnesium, copper, zinc, manganese, phosphorus.Its primary efficacy：
（1）Blood-nourishing is preserved youthful looks, make us skin it is ruddy, radiant, weight reducing beauty.
（2）Hypoferric anemia is prevented, intravascular coagulation is reduced, prevents artery sclerosis and coronary heart disease, cerebral thrombus.
（3）Blood vessel and stomach and intestine rubbish, blood circulation promoting and enriching are removed, strengthening the spleen and stomach, excretion is helped, mitigates stomach and intestine burden, acceleration stomach enteral
The excretion of toxin and discarded object.
（4）There is obvious neutralizing function to the endogenous such as courage, kidney stone foreign matter.
（5）Norcholesterol, blood fat, prevent artery sclerosis.
（6）There is dissolving to make with oxidation to foreign matters such as the hair eaten unintentionally, cereal, husk, wooden slag, sand, metal fillings
With.
（7）Radioresistance and anti-inflammatory, antiulcer, anti-gene mutation.
（8）The functions such as cardiac stimulant, clearing lung-heat moistening lung, regulation endocrine, imbalance.
High-quality green tea mushroom mycelium contains 18 kinds of amino acid of needed by human body, the 8 kinds of ammonia that can not be particularly synthesized containing human body
The nutritional ingredients such as base acid, glucan, mycoprotein, carbohydrate；The ore deposits such as the B family vitamin and iron, potassium, zinc, selenium also enriched
Material element；Its active ingredient is several times or even more than ten times of other mushroom classes.Its primary efficacy is：
（1）Antiulcer and antiinflammatory action.
（2）Antitumor action.
（3）Liver protection function.
（4）Reducing blood lipid and the effect of antiatherosclerosis.
（5）Increase immunity, anti-aging effects.
（6）The influence synthesized to nucleic acid and protein biology.
（7）Body's hypoxia tolerance is improved, increases heart blood output quantity, accelerates body blood circulation.
（8）Reduce the effect of blood glucose.
（9）Radioresistance and antiinflammatory action.
（10）Anticancer, antimutagenic effect.
Wild Ganoderma mycelium contain the black alcohol of polysaccharide, protein, several amino acids, polypeptide, ergot, mannitol, alkaloid,
Coumarin, black body saponin(e, adenine, a variety of enzymes, various trace elements, vitamin B2, vitamin C etc..Primary efficacy：
（1）Strengthen immunologic function, strengthen the body resistance to consolidate the constitution, resist various allergic constitutions, lupus erythematosus, skin disease, benefit internal organ vigour.
（2）Leukopenia, leukaemia, long-term flu, cough and asthma, pulmonary tuberculosis, scrofula.
（3）Coronary heart diseases and angina pectoris, palpitation, arrhythmia cordis, insomnia and dreamful sleep, norcholesterol, triglyceride, prevention are dynamic
The formation of pulse atherosclerosis patch, improves microcirculation.
（4）Good effect is all played to spleen and stomach function decrease, stomach cancer, liver cancer, tumour.
（5）Calm the nerves, it is calm, anticonvulsion, increase wisdom, it is notable to neurasthenia, headache, dizzy effect, to the qi-blood deficiency, moon
It is more suitable to shift to an earlier date through uncomfortable, dysmenorrhoea, amenorrhoea, climacteric metancholia.
（6）Diabetes, progressive muscular dystrophy, the reaction of atrophica high source.Anti-aging, toxin-expelling and face nourishing.
（7）There is auxiliary treatment to cancer, tumour patient, long-term taking can hair care hair care.
Maitake mushroom mycelia has high medical health care function.According to reported in literature, it has the work(for suppressing hypertension and obesity
Effect；Because rich in iron, copper and Vitamin C, it can prevent anaemia, scurvy, leucoderma, prevent the hair of artery sclerosis and cerebral thrombus
It is raw；Its selenium and chromium content is higher, there is protection liver, pancreas, the effect of prevention hepatic sclerosis and diabetes；Se content height makes it also
With preventing and treating Keshan disease, Kaschin-Beck disease and some cardiopathic functions；Its simultaneous calcic and vitamin D, both coordinate, can be effectively
Prevent and treat rickets；The favourable brain development of higher Zn content, holding oxyopia, promote wound healing；The vitamin E of high content
Coordinate with selenium, make it anti-aging, enhancing memory and sensitivity.
Grifola frondosus or noticeable anticancer medicine source, on the one hand, higher Se content resists cancer, especially
It is contained grifolan (Grifolan), based on beta glucan (glucan), wherein active anticancer is most strong, 6 side chains of band
β-(1,3)-glucan account for sizable proportion, it is stated that than appeared on the market lentinan (Lentinan, it is Japanese
PSK), coriolan (PSP in Shanghai) etc. have stronger anti-cancer ability；It is fabulous immunomodulator again simultaneously.As
Chinese medicine, grifola frondosus and umbellate pore furgus are equivalent, can control difficult urination, oedema, tinea pedis, cirrhotic ascites and diabetes etc., are very valuable
Medicinal fungi.
The effect of aweto mycelium has tonifying both YIN and YANG, Conclusion Decreasing controlling nocturnal emission with astringent drugs, benefit the moon tonifying lung.Cordyceps sinensis Main Ingredients and Appearance：Cordyceps sinensis
Acid, cordycepin, amino acid, sterol, mannitol, alkaloid, vitamin B1, B2, polysaccharide and mineral matter etc..Primary efficacy：
（1）Renal function is improved, albuminuria can be removed rapidly to nephrosis, oedema, blood urine, urea chlorine, blood creatinine raises serum egg
In vain, anaemia is improved, row's kidney poison delays the generation of renal failure, kidney tonifying, establishing-Yang, to men and women's sexual desire hypofunction, impotence, morning
Let out, dampness of scrotum, waist soreness, dizzy, tinnitus, muscular atrophy, dermatomyositis has peculiar effect.
（2）Have to chronic bronchitis, cor pulmonale, repeated cold, cough, asthma, in poor health, whole body itch,
Nausea and vomiting, insomnia forgetfulness, night sweat, tubercle bacillus, streptococcus pneumonia has good curative effect.
（3）Delaying cell aging, beauty, weight reducing, chest enlarge prevents testicular senescense, tonifying both YIN and YANG.
（4）Softening blood vessel, reducing blood lipid is hypoglycemic, improves myocardial ischemia, does arrhythmia cordis, calm, anticonvulsion, anti-stop
Arteries and veins is hardened.
（5）Various cancers and various malignant tumours can be improved and suppressed, memory is improved, internal system is adjusted
And nervous system.
Tricholoma matsutake mycelium contains protein, fat and several amino acids, vitamin B1, B2, C and PP cellulose, unsaturated
Aliphatic acid；Gluconic acid, nucleic acid derivative, peptide matters, organic germanium Gel24-239PM, the rare nutrient such as polysaccharide LPB,
It is active with SOD is improved.Primary efficacy：
（1）Immunity is improved, increases anti-virus ability.Tracheitis, Bronchopneumonia, regulating qi-flowing for eliminating phlegm is relieving cough and asthma, the double balls of pneumonia
Bacterium, streptococcus, infected by influenza has inhibitory action.
（2）Accelerate the removing of free radical, delay histoorgan to fail, improve cardiovascular function, enhance metabolism, improve
Body immunity, antiviral, the ability of anti-cell mutation.
（3）To cardiac and cerebral blood supply insufficiency, insomnia, forgetful, antimigraine, vexed, anaemia, hypertension, high fat of blood, diabetes are moved
Arteries and veins hardening has good curative effect.
（4）Fatigue and weak, limbs are sleepy, and full vexed, the nausea and vomiting of chest diaphragm, dysfunction of spleen and stomach, poor appetite, beneficial stomach is mended
Gas, brain tonic and intelligence development.
（5）Anticancer, suppresses tumour, suppresses growth of cancer cells and diffusion.
（6）Psoralen gives birth to marrow, there is good curative effect to bone joint pain.
（7）To waist soreness caused by poor kidney, dampness of scrotum, testicular senescense, prostatitis, frequent micturition, odynuria, urine
Road feel contaminates, the enuresis, increases renal blood flow, and strong essence kidney tonifying regains one's vigor, increases male sex hormone, solves sex dysfunction.
Rainbow conk mushroom mycelium contains a kind of cancer-resisting substance.The bacterium is medicinal, dry, resolving sputum, treat lung disease.Treat chronic bronchial
Scorching, unresolved chronic hepatitis etc. is effective in cure.The medicine that rainbow conk can be treated as liver cancer immunity.Polysaccharide that mycelium is extracted and from hair
It is carcinous that the polysaccharide extracted in zymotic fluid is respectively provided with strong suppression.Inhibiting rate to small white mouse sarcoma 180 and ehrlich carcinoma is respectively 80% He
100%.Rainbow conk mushroom mycelium or a kind of fungi for having a variety of metabolites, there is protease, peroxidase, amylase, laccase
And leather enzyme etc., there is its extensive economic use.Primary efficacy：
1st, body's immunity is improved：Rainbow conk thalline Polysaccharides on Mice peritoneal macrophage can strengthen its phagocytosis, to ring phosphorus
Spleen atrophy has antagonism caused by acid amides.Coriolan peptide (PSP) can substantially increase illuminated mice serum lysozyme
Content and spleen index, it is believed that there is facilitation to the non-specific immune function of macrophage.Interferon inducted and Stimulation effect
Result of the test show that the antitumor and immunoregulation effect of coriolan peptide may have interferon inducted and Stimulation effect with it
Ability is relevant.Rat continuous oral coriolan peptide can promote lymphocyte transformation in 20g/kg/ days, and serum IgG titers substantially rise
Height, can also cancel Rat Septal day and take suppression of the endoxan 400mg/kg to Natural killer activity.Seen with chemoluminescence method
Observe, after coriolan is injected through abdominal cavity, Turnover of Mouse Peritoneal Macrophages respiratory burst function can be strengthened to tert-butyl group hydroperoxidation
The resistance of thing damage.Macrophage glutathione peroxidase (GSHPx) basal viability of coriolan processing is significantly carried
Height, under tert-butyl hydroperoxide effect, the macrophage of coriolan processing still has higher glutathione peroxidase
Enzyme activity.Antioxidase activity can be improved by illustrating that coriolan has as immunostimulant, protection macrophage resistance activity
The effect of oxygen injury.Take the malignant tumor patient of coriolan, its T3, T4 lymphocyte subgroup and white blood cell count(WBC), compared with
Dramatically increased before medicament for the eyes, it is believed that be a kind of preferable BRM.Coriolan is to by OxLDL ELISA (O-
LDL) the fat accumulation that infringement mouse macrophage is caused, there is protective effect, and can suppress the denaturation of macrophage foam cell formation sample, improves
Macrophage response ability.The murine interleukin caused to endoxan, which is reduced, has obvious rise to act on, and can activate in netted
The function of dermal system.The IL-2, lymphotoxin and gamma interferon of splenocyte generation level are remarkably improved, abdomen is significantly increased
The ability of chamber macrophages secrete TNF and IL-1.
2nd, antitumor action：Coriolan (PSK) has suppression to make to euphorbia egg decoctum, Ehrlich tumor and gland cancer 755
With.Coriolus Versicolor P.E. is taken to mouse within 10 days before tumour transplatation, the ascitogenous sarcoma S180 of 12 days has substantially after being transplanted to mouse
Inhibitory action, 22 days tumor-inhibiting actions weaken after transplanting.The wild Coriolus Versicolor P.E. of different regions is compared, no matter Shaanxi cloud
Sesame or Changbai Mountain rainbow conk, there is obvious tumor-inhibiting action to S180.Rainbow conk bacterial strain is in fungi cylinder accumulation polysaccharide, also to nutrient solution
Exocellular polysaccharide is secreted, the former is glucan, can suppress mouse S180, and have activation to macrophage.The latter is a variety of lists
The heteroglycan of sugar composition, has a certain degree of immune activation to act on, but without obvious tumor-inhibiting action.Semifinished product such as rainbow conk mycelia hot water
Extract, is 77.5% to S180 inhibiting rates, highly finished product activity is increased, to S180 inhibiting rates up to 99.3%.Because PSK can substantially press down
Thing kinds of tumors is braked, antitumor spectra is wider, with certain clinical efficacy, therefore has caused extensive attention, and existing many moneys
Material proves what its Synergistic action was to determine.PSK is different due to extracting method, and tumour inhibiting rate difference, experiment shows：Redox
And the polysaccharide that partial hydrolysis method is extracted, tumor-inhibiting action is stronger.The polysaccharide extracted through gasification, reduction can significantly extend survival rate.
PSk may act on the growth course of tumour cell as chemopreventive agent, strengthen T cell and NKT (NK)
The effect of cell, there is anti-distortion, prevention chromosome damage and immunoregulation effect.
3rd, study of anti-atherogenic effect：Experiment proves that coriolan (PSK) can effectively suppress atherosclerotic plaque
The formation and development of block.PSK group aorta atheromatous plaque surface areas are significantly less than big or middle point of coronary artery in control group, heart wall
The stenosis of branch are also lighter than control group.PSK has protective effect to Experimental Atherosclerotic Rabbits lipid peroxidation injury,
It can effectively damage anti-lipid peroxidation, strengthen the gene expression of macrophage selenium glutathione peroxidase.Improve huge
Phagocytic immunity respond and suppress its foam sample denaturation, to suppress artery sclerosis it is beneficial, can mitigate rabbit move
Pulse atherosclerosis are formed, the rabbit to having formed atherosis, also there is therapeutic action.Experiment proves that PSK can improve abdominal cavity macrophage
Combination of the cell to acetyl low-density lipoprotein (ac LDL), interior shifting and degraded are overall to play lipid-loweringing, anti arteriosclerosis effect.
4th, the effect of Central nervous system：Coriolan (PSK) can improve mouse and learning and memory function, to east
Learning and memory in rats obstacle caused by hyoscyamine, improves significantly.PSK can strengthen the syngignoscism of amobarbital, rainbow conk
Peptidoglycan (PSP) also has certain sedation, can suppress the pain reaction of mouse, but it is slow to work, and the duration is long.
5th, other are acted on：
5.1. hypoglycemic effect：Mouse blood sugar is up to 362.4mg/100ml, with can be down to 126.6mg/ after coriolan (PSK)
100ml, on euglycemia without influence.To blood glucose rise 355.6mg/100ml after normal mouse injection alloxan, such as give in advance
PSK is given, then blood glucose only rises to 209mg/100ml, show that there is preventing and treating blood glucose rise effect.
5.2.PSP the experimental stomach such as stress in rats, pyloric ligation ulcers, acetic acid type and Indomethacin (indocin) type is burst
Ulcer, there is obvious inhibitory action.
5.3.PSK containing several amino acids, glycopeptide and various trace elements calcium, germanium, magnesium, iron, zinc etc..Intracellular Polysaccharide of Poly-stictus Versicolor PS-K has
There is certain antihepatitic activity, can improve physically weak weak, the symptom such as poor appetite.PSK has necessarily to hepatitis B replication
Inhibitory action.
5.4.PSk the young fly number of food number of times, number of copulations and the F1 of fruit bat can substantially be increased.And extend female fly
Average life span, maximum life span and half death time.But poor is acted on to male fly, does not extend average life span and half is dead
Time.
5.5. Micronuclei In The Mouse Bone Marrow test shows：The PV-1 that PSK and China extract is to caused by mutagenic agent endoxan
Chromosome damage has antagonism.Also there is antagonism to smoke from cigarette contamination mutagenesis.PSK is to endogenous cytotoxic factor
There is facilitation.
5.6.PSK having prevents oxidative damage and antinociceptic effect.Cause to materials such as croton oil, smog and endotoxins is scorching
There is antagonism, can significantly be extended its time-to-live to barium chloride proarrhythmia, adrenaline induction acute pulmonary edema mouse
And survival rate.
6th, toxicity and adverse reaction：Coriolan peptide (PSP) mouse peritoneal median lethal dose is 300.36mg/kg, orally
Maximal tolerance dose is 20g/kg, there is not yet dead mouse, illustrates its minimum lethal dose MLD>20g/kg.Oral Administration in Rats PSK1.5g/
Kg 130 times of clinical dosage (be), continuous 60 days, none was dead for 20 rats, shows that oral medication reacts without long term toxicity.It is real
Test and show that PSK is a toxicity very low material, also without mutagenesis.
Hericium mycelium contains 7 kinds of amino acid needed by human, fat, vitamin A, vitamin B1, B2 and niacin,
Polysaccharide body, polypeptide and trace element, calcium, phosphorus, food fiber, also contain copper, and copper is the indispensable micronutrient of human body.It is main
Want effect：
（1）To gram-positive bacteria, the microbial gastrointestinal ulceration of helicobacter pylorus can repair impaired mucous membrane Healing, reduce
Drink beyond one's capacity the injury to intestines and stomach.
（2）To acute or chronic gastritis, atrophic gastritis, superficial gastritis, gastric and duodenal ulcer, stomach cold, hydrochloric acid in gastric juice, stomach
Swollen, gastroptosis, gastric mucosa come off, and indigestion, apocleisis, partial eclipse, disorder of function of stomach has good curative effect.
（3）Hypoxia-bearing capability is improved, reducing blood lipid, norcholesterol prevents serial cardiovascular and cerebrovascular disease caused by artery sclerosis.
（4）Long-term taking can eliminate the delicate beauty of senile plaque expelling, skin.
（5）To stomach cancer, intestinal cancer, cardiac cancer, tumor in digestive tract effective percentage 69.3%, digestive tract ulcer 85.6%.
The composition of the treatment breast cancer is made a general survey of, is that an a variety of mycelium are combined, with Poria mycelium, honey
Based on ring bacterium mycelium, supplemented by other mycelium, the compound of composition, because prescription is rigorous, bring out the best in each other, effect it is notable.
Embodiment
The present invention is further described below with reference to specific embodiment：
Embodiment 1：
A kind of active mycelium group with treatment breast cancer of the present invention closes, by weight percentage by Poria mycelium 30%, sweet ring
Bacterium mycelium 20%, shiitake mushroom hypha 7%, the, of shaggy mane mycelium body 7% Auricularia mycelium 5%, high-quality green tea mushroom mycelium 5%, Wild Ganoderma
Mycelium 5%, maitake mushroom mycelia 5%, aweto mycelium 4%, tricholoma matsutake mycelium 4%, prepared from coriolus versicolor mycelium 4%, hericium mycelium
Body 4% is constituted.
Embodiment 2：
A kind of active mycelium group with treatment breast cancer of the present invention closes, by weight percentage by Poria mycelium 26%, honey
Ring bacterium mycelium 24%, shiitake mushroom hypha 7%, the, of shaggy mane mycelium body 7% Auricularia mycelium 6%, high-quality green tea mushroom mycelium 6%, wild spirit
Camphorata mycelium 4%, maitake mushroom mycelia 4%, aweto mycelium 5%, tricholoma matsutake mycelium 5%, prepared from coriolus versicolor mycelium 3%, hericium erinaceus
Filament 3% is constituted.
Embodiment 3：
A kind of active mycelium group with treatment breast cancer of the present invention closes, by weight percentage by Poria mycelium 25%, honey
Ring bacterium mycelium 20%, shiitake mushroom hypha 6%, the, of shaggy mane mycelium body 6% Auricularia mycelium 7%, high-quality green tea mushroom mycelium 7%, wild spirit
Camphorata mycelium 7%, maitake mushroom mycelia 7%, aweto mycelium 5%, tricholoma matsutake mycelium 5%, prepared from coriolus versicolor mycelium 3%, hericium erinaceus
Filament 2% is constituted.
Embodiment 4：
A kind of active mycelium group with treatment breast cancer of the present invention closes, by weight percentage by Poria mycelium 24%, honey
Ring bacterium mycelium 22%, shiitake mushroom hypha 7%, the, of shaggy mane mycelium body 6% Auricularia mycelium 6%, high-quality green tea mushroom mycelium 6%, wild spirit
Camphorata mycelium 6%, maitake mushroom mycelia 6%, aweto mycelium 4%, tricholoma matsutake mycelium 4%, prepared from coriolus versicolor mycelium 5%, hericium erinaceus
Filament 4% is constituted.
Embodiment 5：
A kind of preparation method that there is the active mycelium group for treating breast cancer to close is as follows：
1st, the preparation method of Poria mycelium：Wild Poria cocos passes through tissue and separates, cultivates, extracts, concentrates, freezes, is dried in vacuo,
Obtain Poria mycelium；
2nd, the preparation method of armillaria mycelium：Wild halimasch is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain armillaria mycelium；
3rd, the preparation method of shiitake mushroom hypha：Wild-type champignon passes through tissue and separates, cultivates, extracts, concentrates, freezes, is dried in vacuo,
Obtain shiitake mushroom hypha；
4th, the preparation method of shaggy mane mycelium body：Wild coprinus comatus is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain shaggy mane mycelium body；
5th, the preparation method of agaric mycelium：Wild black fungus bacterial passes through tissue and separates, cultivates, extracting, concentrating, freezing, very
Sky is dried, and obtains agaric mycelium；
6th, the mycelial preparation method of high-quality green tea mushroom：Wild high-quality green tea mushroom is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain high-quality green tea mushroom mycelium；
7th, the mycelial preparation method of Wild Ganoderma：Wild Ganoderma passes through tissue and separates, cultivates, extracts, concentrates, freezes, is dried in vacuo,
Obtain Wild Ganoderma mycelium；
8th, the preparation method of maitake mushroom mycelia：Wild Grifola frondosa is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain maitake mushroom mycelia；
9th, the preparation method of aweto mycelium：Wild cordyceps by tissue separation, culture, extract, concentration, it is lyophilized,
Vacuum drying, obtains aweto mycelium；
10th, the preparation method of tricholoma matsutake mycelium：Wild matsutake is done by tissue separation, culture, extraction, concentration, lyophilized, vacuum
It is dry, obtain tricholoma matsutake mycelium；
11st, the preparation method of prepared from coriolus versicolor mycelium：Wild rainbow conk is done by tissue separation, culture, extraction, concentration, lyophilized, vacuum
It is dry, obtain prepared from coriolus versicolor mycelium；
12nd, the preparation method of hericium mycelium：Wild Hericium erinaceus is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain hericium mycelium；
13rd, by Poria mycelium obtained above, armillaria mycelium, shiitake mushroom hypha, shaggy mane mycelium Ti, fungus mycelium
Body, high-quality green tea mushroom mycelium, Wild Ganoderma mycelium, maitake mushroom mycelia, aweto mycelium, tricholoma matsutake mycelium, rainbow conk mycelia
Body, hericium mycelium are crushed, are milled respectively, mix in proportion, and cross the sieve of 300 mesh, 300 purposes are made thin
The sterilized fine powder handled well, is loaded capsule by powder, and a kind of active mycelium group compound for having and treating breast cancer is just made
Capsule；
The sterilized pulvis handled well is made pellet, dried, whole grain, just be made it is a kind of have treatment breast cancer active bacteria
The granule of silk group compound（Electuary）；
The sterilized pulvis handled well is loaded the screen pack of 300 mesh, then immerse in 60 degree of pure grain daqu fermentation wine and carry out 6
To the secondary fermentation of 12 months, by allotment, filtering, a kind of active mycelium group compound with treatment breast cancer is just made
Vina.
The present invention is a kind of to have the active mycelium group compound therapeutic effect for treating breast cancer：
In the case where patient agrees to, there is the active mycelium group compound for the treatment of breast cancer using this, to 20 breast cancer diseases
Patient is treated.On the premise of patient is voluntary, the active mycelium group compound of present invention treatment breast cancer is taken, daily
Secondary, early to take before meals, before evening sleep, warm water takes, and even served 15 days, is 1 course for the treatment of, continuously takes 6 courses for the treatment of.
Therapeutic effect：In terms of general health quality, wherein：10 patient pain's symptoms are substantially eliminated, and sleep is changed
Kind, symptoms of breast cancer is eased, and 2 patient outcomes are not obvious.
In terms of tumor of breast is suppressed, the active mycelium group with treatment breast cancer that 8 patients take the present invention closes
After thing treatment, on inspection, 7 patient tumors lumps substantially diminish, lump substantially softens, and 1 patient outcome is not obvious.
Claims (6)
1. a kind of have the active mycelium group compound for treating breast cancer, it is characterised in that：Poria mycelium 26~31%, sweet ring
Bacterium mycelium 20~24%, shiitake mushroom hypha 6~8%, the, of shaggy mane mycelium body 6~8% Auricularia mycelium 4~6%, high-quality green tea mushroom bacterium
Filament 4~6%, Wild Ganoderma mycelium 4~6%, maitake mushroom mycelia 4~6%, aweto mycelium 3~5%, tricholoma matsutake mycelium 3
~5%, the formulation that prepared from coriolus versicolor mycelium 3~5%, monkey head mushroom filament 3~5% are constituted is pill, capsule or vina.
2. a kind of active mycelium group compound with treatment breast cancer according to claim 1, it is characterised in that：By weight
Percentage is measured by Poria mycelium 26~31%, armillaria mycelium 20~24%, shiitake mushroom hypha 6~8%, shaggy mane mycelium body 6
~8%, Auricularia mycelium 4~6%, high-quality green tea mushroom mycelium 4~6%, Wild Ganoderma mycelium 4~6%, maitake mushroom mycelia 4~6%,
The agent that aweto mycelium 3~5%, tricholoma matsutake mycelium 3~5%, prepared from coriolus versicolor mycelium 3~5%, hericium mycelium 3~5% are constituted
Type is pill, capsule or vina.
3. a kind of active mycelium group compound with treatment breast cancer according to claim 2, it is characterised in that：By weight
Percentage is measured by Poria mycelium 26~31%, armillaria mycelium 20~24%, shiitake mushroom hypha 6~8%, shaggy mane mycelium body 6
~8%, Auricularia mycelium 4~6%, high-quality green tea mushroom mycelium 4~6%, Wild Ganoderma mycelium 4~6%, maitake mushroom mycelia 4~6%,
The agent that aweto mycelium 3~5%, tricholoma matsutake mycelium 3~5%, prepared from coriolus versicolor mycelium 3~5%, hericium mycelium 3~5% are constituted
Type is pill, capsule or vina.
4. according to a kind of any described active mycelium group compound with treatment breast cancer of claims 1 to 3, its feature exists
In：Described formulation is formulation described in any pharmacy.
5. a kind of active mycelium group compound with treatment breast cancer according to claim 4, it is characterised in that：It is described
Formulation be pill, capsule or vina.
6. according to a kind of preparation side of any described active mycelium group compound with treatment breast cancer of Claims 1 to 5
Method, it is characterised in that comprise the steps of：
1）The preparation method of Poria mycelium：Wild Poria cocos passes through tissue and separates, cultivates, extracts, concentrates, freezes, is dried in vacuo,
Obtain Poria mycelium；
2）The preparation method of armillaria mycelium：Halimasch passes through tissue and separates, cultivates, extracts, concentrates, freezes, is dried in vacuo,
Obtain armillaria mycelium；
3）The preparation method of shiitake mushroom hypha：Wild-type champignon passes through tissue and separates, cultivates, extracts, concentrates, freezes, is dried in vacuo,
Obtain shiitake mushroom hypha；
4）The preparation method of shaggy mane mycelium body：Wild coprinus comatus is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain shaggy mane mycelium body；
5）The preparation method of agaric mycelium：Wild black fungus is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain agaric mycelium；
6）The mycelial preparation method of high-quality green tea mushroom：Wild high-quality green tea mushroom bacterium passes through tissue and separates, cultivates, extracting, concentrating, freezing, very
Sky is dried, and obtains high-quality green tea mushroom mycelium；
7）The mycelial preparation method of Wild Ganoderma：Wild Ganoderma passes through tissue and separates, cultivates, extracts, concentrates, freezes, is dried in vacuo,
Obtain Wild Ganoderma mycelium；
8）The preparation method of maitake mushroom mycelia：Wild Grifola frondosa is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain maitake mushroom mycelia；
9）The preparation method of aweto mycelium：Wild cordyceps by tissue separation, culture, extract, concentration, it is lyophilized,
Vacuum drying, obtains aweto mycelium；
10）The preparation method of tricholoma matsutake mycelium：Wild matsutake is done by tissue separation, culture, extraction, concentration, lyophilized, vacuum
It is dry, obtain tricholoma matsutake mycelium；
11）The preparation method of prepared from coriolus versicolor mycelium：Wild rainbow conk is done by tissue separation, culture, extraction, concentration, lyophilized, vacuum
It is dry, obtain prepared from coriolus versicolor mycelium；
12）The preparation method of hericium mycelium：Wild Hericium erinaceus is by tissue separation, culture, extraction, concentration, lyophilized, vacuum
Dry, obtain hericium mycelium；
13）, by Poria mycelium obtained above, armillaria mycelium, shiitake mushroom hypha, shaggy mane mycelium Ti, agaric fungus
Filament, high-quality green tea mushroom mycelium, Wild Ganoderma mycelium, maitake mushroom mycelia, aweto mycelium, tricholoma matsutake mycelium, manyzoned polypore bacteria
Filament, hericium mycelium are crushed, are milled respectively, mix in proportion, and cross the sieve of 300 mesh, 300 purposes are made thin
The sterilized fine powder handled well, is loaded capsule by powder, and a kind of active mycelium group compound for having and treating breast cancer is just made
Capsule；Or the sterilized pulvis handled well made pellet, dried, whole grain, being just made a kind of has treatment breast cancer
The granule of active mycelium group compound（Electuary）；Or the sterilized pulvis handled well is loaded the screen pack of 300 mesh, then
The secondary fermentation of progress 6 to 12 months in the pure grain daqu fermentation wine of 60 degree of immersion, by allotment, filtering, is just made a kind of
The vina of active mycelium group compound with treatment breast cancer.
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