CN104382007B - Functional capsule and preparation method thereof - Google Patents

Functional capsule and preparation method thereof Download PDF

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Publication number
CN104382007B
CN104382007B CN201410572517.8A CN201410572517A CN104382007B CN 104382007 B CN104382007 B CN 104382007B CN 201410572517 A CN201410572517 A CN 201410572517A CN 104382007 B CN104382007 B CN 104382007B
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capsule
mycelium
functional capsule
abelmoschus esculentus
blood
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CN104382007A (en
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庄济诚
李祥麟
周锦明
钱玉华
王岚
石玉洁
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SUZHOU YUANMENG NEW ENERGY ENVIRONMENTAL PROTECTION TECHNOLOGY Co Ltd
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SUZHOU YUANMENG NEW ENERGY ENVIRONMENTAL PROTECTION TECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L31/00Edible extracts or preparations of fungi; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01GHORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
    • A01G18/00Cultivation of mushrooms

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  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a functional capsule and a preparation method thereof. The functional capsule is composed of the following raw materials: 70-90 nutritional feed extracted from Abelmoschus esculentus, mushrooms, algaes and mulberry leaves, and 10-30 myceliums; Biological engineering technology is applied in the present invention, medicinal and edible plants with a certain function are chosen, hot water is used to extract active ingredients from various plants, effective and beneficial substances have a high content and a good effect. Daily administration of the functional capsule can improve the sub-healthy condition, prevent or auxiliarily treat some diseases.

Description

A kind of Functional capsule and preparation method thereof
Technical field
The invention belongs to a kind of containing Abelmoschus esculentus, bacterium, the Functional capsule of algae vegetable composition, particularly relate to a kind of functional Capsule and preparation method thereof.
Background technology
Air, pollution of waterhead in recent years is day by day serious, gas (as) wait abnormality;The change of the temperature difference, sleet is rapid greatly, promotes source of disease bacterium Strengthen Deng variation, burst disease (SARS, bird flu etc.), make human body that the adaptation ability of environment to be declined;The illegallest, without good business People makes and sell of poor quality, adds poisonous/pest matter (water-injected meat, waste oil, tripolycyanamide etc.), promotes people's resist the disease ability (immunity) declines, and is in sub-health state, accelerates disease (cancer) and development and old and feeble process occur.
To this end, we are while the air striving for cleaning and water source, it is necessary to strengthen the protection of self, except suitably taking exercise Motion, food is requisite, and the food with food therapy function is one of kind of people's prioritizing selection.
The application of functional food is the problem paid much attention to both at home and abroad at present, and its development trend is the hugest and far-reaching, along with External culture extensively exchange, " dietetic therapy " of China is the most incoming all over the world, and even some product becomes external patent, " rhubarb wine " as famous in Italy, this wine has appetizing ante cibum, helps digestion after meal, and the effect of relieving constipation next day has often been drunk Bowel relieving stomach, the effect of life lengthening, the character of this wine is many masses and occidentals to NORTHWEST CHINA area with cattle and sheep meat Group shot enters the crowd of the living habit such as higher fatty acid, high protein and plays good dietary function." gin " of the U.S., France " bucket nurse wine " is all relevant with " dietetic therapy " medicine of China with " breathing out nurse wine " etc., it can be seen that " dietetic therapy " is also by the people all over the world Attention commonly used.According to incompletely statistics, Singaporean (2006) reaches 65,000,000 dollars for the expense of dietetic therapy.
Brainstrust is foretold: the important breakthrough in terms of health care from now on is primarily not the new invention from medicine, but from more Add rational dietary structure and life style, it is believed that " dietary structure " described in brainstrust contains in fact has dietetic therapy work " functional food ".
" integration of edible and medicinal herbs " and " medicine food with " is exactly known to us, the Fructus Jujubae often eaten such as us, Semen Sesami Nigrum, Tremella, lotus Son etc., is ticbit, is again the medicine cured the disease.They component contents have the effect of regulation Human Physiology balance.When Human Physiology changes (unbalance) or suffers just to lose regulating power when infecting (pathogenic bacteria invasion) and ill.The most such as give phase The functional food answered, just can promote it to recover regulating power, reach diseases prevention and the purpose cured the disease, as suffered from anemofrigid cold, endure a life Rhizoma Zingiberis Recens Herba Alii fistulosi plain soup is drunk;Aphtha of the mouth and tongue drinks sweet mung bean soup ... like this, too numerous to enumerate.
" dietetic therapy " and " dietetic therapy (sick) " is the medical legacy that China is precious, found that as far back as B.C. 579 years and controls with distillers yeast Gastroenteropathy, just has the literature record that diet is cured the disease, epoch the brightest from business, clear, the monograph that special record diet is cured the disease before the Warring states There are kind more than 600, thus effect of sequitur dietetic therapy.
Summary of the invention
In order to obtain nutrient health that there is food therapy function, that be convenient for carrying, it is an object of the invention to provide a kind of merit Can property capsule and preparation method thereof, demand that is that solve integration of edible and medicinal herbs and tonic and that be convenient for carrying.Institute in this formula Plant, all contain the particular matter of needed by human body, prevention of disease, the raising of body constitution have obvious effect, scalable Human body yin-yang balancing, nourishes comprehensively and improves resistance, and slow down aging, is tonic non-defective unit.
Each compositions selection gist used by the present invention and composition, function description:
1, Abelmoschus esculentus
Formal name used at school Hibiacus esculengtus belongs to Malvaceae, annual herb plant.Abelmoschus esculentus has another name called Flos abelmoschi manihot, Cornu Caprae seu Ovis Bean, plant viagra etc., originate in Africa, before more than 2000 years, Egypt has cultivated, the most gradually expanding species (introducing) U.S., day The ground such as basis, Southeast Asia, the plantation of the existing Abelmoschus esculentus of Ancient Times in China, ground expands plantation from China in last century Jiangsu, Shandong, Beijing etc. And moral education into native breed, such as: Beijing Abelmoschus esculentus, Beijing Rodococcus sp J-5 etc. nearly more than 20 is planted in various places, as komatsuna-cutter (overlapping) kind between bean-Abelmoschus esculentus, yield is a lot, and between Shandong Jiang Yuan Herba Alii fistulosi and Abelmoschus esculentus, (overlapping) plants.
The fruit pod of Abelmoschus esculentus, seed, tender leaf all can eat as vegetable;Containing water-soluble fibre fruit in the tenderest fruit pod The stick-slip liquid of the compositions such as glue, galactan, Radix Acaciae senegalis, has special fragrance.Possibly together with abundant vitamin A, Vb, Vc And the element such as Fe, K, P, Zn, Cu, its protein content reaches 15%~26%, carbohydrate is 6.4%, fat 2%, fine The every 100 grams of heats that 150 kilojoules can be provided of dimension element 1%, concrete composition such as table 1 below
Tender okra pod nutrient component meter (every 100 grams of content) table 1
Components Name Content Components Name Content Components Name Content
Edible portion 88 Moisture (gram) 86.2 Energy (kilocalorie) 37
Energy (kilojoule) 155 Protein (gram) 2 Fat (gram) 0.1
Carbohydrate (gram) 11 Dietary fiber (gram) 3.9 Cholesterol (milligram) 0
Ash (gram) 0.7 Vitamin A (milligram) 52 Carotene (milligram) 310
Retinol (milligram) 0 Thiamine (microgram) 0.05 Riboflavin (milligram) 0.09
Nicotinic acid (milligram) 1 Vitamin C (milligram) 4 Vitamin (T) (milligram) 1.03
a-E 0.92 (β-γ)-E 0.11 δ-E 0
Calcium (milligram) 45 Phosphorus (milligram) 65 Potassium (milligram) 95
Sodium (milligram) 3.9 Magnesium (milligram) 29 Ferrum (milligram) 0.1
Zinc (milligram) 0.23 Selenium (milligram) 0.51 Copper (milligram) 0.07
Manganese (milligram) 0.28 Iodine (milligram) 0
Wherein the liquid of special (very) stick-slip can substantially strengthen the energy of human body, disperses fatigue, more can effectively stimulate man Sexual centre is neural, accelerates blood circulation, enhances metabolism, make systemic organs's microcirculatory vascular activate, especially with penis sponge Body ... the mucus being additionally mixed with other composition can also help digest, treatment gastritis, gastric ulcer, heart disease, apoplexy, sclerotin are dredged Pine and senile dementia (Alzheimer) disease.Skin (especially with face) also had wrinkle removal, the effect of smooth exquisiteness.
2, fungi plant
2.1, Cordyceps militaris (L.) Link.
The composition function of Cordyceps militaris (L.) Link., the national patent being approved according to us:
A, Li Xianglin etc. " antisenescence medicinal composition and preparation method thereof ", patent No. ZL02121396.8 International Classification of Patents Number: A61K 35/78;
B, Li Xianglin etc. " improve phycomycete food of athlete's physique and preparation method thereof ", patent No. ZL03153155.5 state Border Patent classificating number: A23L 1/28;
C, Yang Jie, Li Xianglin etc. " utilizing the method that Cordyceps militaris (L.) Link. cocoon prepares health-care edible capsule ", the patent No. 201210394933.4;
D, Yang Jie, Li Xianglin etc. " method preparing the business alcoholic drink mixed with fruit juice of health food (treatment) with Cordyceps militaris (L.) Link. cocoon extract ", specially Profit 201210394729.X;
E, Yang Jie, Li Xianglin etc. " prepares fuel beverage and the side of electuary of health food with Cordyceps militaris (L.) Link. cocoon extract Method ", patent No. 201210393512.X;
Its composition function in above-listed patent all it is stated that, repeat no more herein.
2.2, Hericium erinaceus (Bull. Ex Fr.) Pers.
Hericium erinaceus (Bull. Ex Fr.) Pers. protein content is higher, and every hectogram contains 26.3 grams of protein, containing more much higher sugar, mineral and Wei Sheng Element, 18 kinds of aminoacid (wherein having 8 kinds is that human body is necessary) bran histidine contents the highest (0.64mg/g), Hericium erinaceus (Bull. Ex Fr.) Pers. is containing unsaturation Fatty acid, can reduce cholesterolemia and content of triglyceride, regulates blood fat, beneficially blood circulation, is the ideal of cardiovascular patient Food;Polysaccharose substance isoreactivity material suppression helicobacter pylori (gastric cancer), has raising body immunity, slow down aging; Every fatty 4.2 grams of hectogram hedgehog hydnum, is genuine high protein, low-fat food, the most also rich in various vitamin and nothing Machine salt.Hericium erinaceus (Bull. Ex Fr.) Pers. has appetite stimulator, strengthens gastric mucosal barrier function, improves lymhocyte transformation rate, promotes the effects such as leukocyte. Therefore human body can be made to improve the immunocompetence to disease;Containing several amino acids and abundant polysaccharide body in Hericium erinaceus (Bull. Ex Fr.) Pers., can help and disappear Change, to digestive tract disease such as gastritis, gastric cancer, esophageal carcinoma, gastric ulcer, duodenal ulcer, superficial gastritis, neurasthenia, dizzy The diseases such as dizzy, sexual impotence have curative effect, and treatment intestinal cancer is had assosting effect;Elderly and infirm eats Hericium erinaceus (Bull. Ex Fr.) Pers., has nourishing and fit keeping function Effect;The polysaccharide body that it contains, many peptides and fatty material, the synthesis of hereditary material in energy anticancer, thus prevent With treatment alimentary tract cancer and other malignant tumor;Hedgehog hydnum or good nourishing food, have neurasthenia, digestive tract ulcer Good efficacy.In screening anticancer medicine, find that it has obvious anticancer function to skin, muscle cancerous protuberance.So often eating Hericium erinaceus (Bull. Ex Fr.) Pers., The anosis resistance against diseases that can strengthen, the ill effect that can treat disease;Carry, Hericium erinaceus (Bull. Ex Fr.) Pers. sweet in the mouth, property according to " China's medicinal fungi " Flat, can profit the five internal organs, aid digestion, nourishing, to digestive tract disease-gastric and duodenal ulcers, neurasthenia has good curative effect. Numerous food and medicine it are made at present.The traditional Chinese medical science is thought, the flat sweet in the mouth of Hericium erinaceus (Bull. Ex Fr.) Pers. property, favourable the five internal organs, aid digestion, nourish the body Etc. effect.Since 20 century 70s, modern medicine proves that Hericium erinaceus (Bull. Ex Fr.) Pers. has good medical value successively, and clinical practice shows, Hericium erinaceus (Bull. Ex Fr.) Pers. can treat the diseases such as dyspepsia, gastric ulcer, antral gastritis, stomachache, flatulence and neurasthenia.And slightly neurasthenia suffers from Person, edible Hericium erinaceus (Bull. Ex Fr.) Pers. be can yet be regarded as and preferably assists treatment.On clinical practice, Hericium erinaceus (Bull. Ex Fr.) Pers. is used to treat, for slightly Or severe neurological is weak all can obtain more notable preferably curative effect.
2.3, Poria
Containing pachymic acid, β-pachyman, triterpenoid compound ethylene pachymic acid and natural gum, chitin, protein, fat Fat, lecithin, glucose, adenine, histidine, choline, β-pachyman catabolic enzyme, lipase, protease etc., contained Poria Acid has the effect of enhancing immunity, antitumor and calmness, blood sugar lowering etc.;Poria is mainly composed of pachyman, contains Measure the highest.Various bacteria there is inhibitory action;Gastric acid can be dropped, digestive tract ulcer is had preventive effect;Hepatic injury is had significantly Protective effect;There is antineoplastic action;Many-sided immunologic function can be adjusted;Leukopenia caused by chemotherapy can be made to accelerate Go up;And have the effect of calmness;Cure mainly eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming, control urine and pay no attention to, edema is swollen (expiring), phlegm retention The functions such as vomiting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful, blood sugar lowering;Anticancer, the clinical conventional treatment esophageal carcinoma, gastric cancer, hepatocarcinoma, The carcinoma such as nasopharyngeal carcinoma, carcinoma of tongue, breast carcinoma, bladder cancer, pulmonary carcinoma, exedens melanoma belong in insufficiency of the spleen leading to overabundance of dampness, phlegm retention stop, damp and hot Stop up knot person etc..
2.4, Ganoderma
Ganoderma includes K, P, Mg, Ca, Na, Fe, Cu, Mn and the multiple element such as germanium, selenium and Ganoderma triterpenoids nucleotide.Amino Acid polypeptide, enzyme, polysaccharide etc., isolated ganoderan kind more than 200 the most from Ganoderma, wherein most be β-dextran, Research confirms that this polysaccharide can suppress the generation of free radical, strengthens the phagocytic activity of macrophage, improves body hypoxia-bearing, strengthens The activity of SOD Superoxide dismutase, suppression oxygen-derived free radicals produces and erythrocyte lipid peroxidation reacts, and improves liver, bone marrow, blood synthesis DNA (DNA (deoxyribonucleic acid)) and the ability of RNA (ribonucleic acid) protein;Ganoderan be Ganoderma principle active component it One, there is antitumor, immunomodulating, blood sugar lowering, antioxidation, blood fat reducing and anti-aging effects.Triterpenes contained by Ganoderma does not descend hundred Remaining kind, wherein based on tetracyclic triterpenes, the bitterness of Ganoderma is relevant with contained triterpenes, and triterpenes is also the effective ingredient of Ganoderma One of, human liver cancer cell is had cytotoxicity, also can suppress the release of histamine, there is hepatoprotective effect and there is antiallergic Effect etc.;Belonging to tradition valuable ingredient of Chinese medicine, possess the highest medical value, the modern pharmacology through scientific research institution's many decades is studied Confirming, Ganoderma, for strengthening body immunity, regulates blood glucose, controls blood pressure, adjuvant therapy chemicotherapy, hepatoprotective, promotes to sleep The aspects such as dormancy are respectively provided with significant curative effect.
3 algae
3.1, the composition function of spirulina (arthrospira), according to the national patent that we are the most granted:
A, Zeng Zhaoqi, Li Xianglin etc. " joint (spiral shell) rotation algae health-care food composition and preparation method thereof ", the patent No. CN94112205.0;
B, Zeng Zhaoqi, Li Xianglin etc. " blunt epimerite (spiral shell) rotation algae albumen and the application thereof " patent No.: CN94109295.X;
C, Li Xianglin etc. " fuel that relieves the effect of alcohol (beverage), the manufacture method of relieving alcoholic intoxication capsule, the patent No.: ZL200410090707.2, its composition function illustrates in above-listed patent, the most no longer repeats.
3.2, Thallus Porphyrae
Its protein, ferrum, phosphorus, calcium, riboflavin, carotene equal size occupy the hat of various vegetable, therefore Thallus Porphyrae has again " nutrition Treasure-house " laudatory title.Every 100 grams of inner proteins 28.2 grams, fat 0.2 gram, carbohydrate 48.5 grams, Ca343mg, P457mg, Fe33.2mg, carotene 1.23mg, vitamin B1 1.8mg, VB2 2.07mg, nicotinic acid 5.1mg, vitamin C 1.0mg, iodine 1.8mg, in research confirms Thallus Porphyrae now, the content of VA is 67 times of milk, and particularly content of iodine is higher, and this is the most pre- Anti-endemicity thyromegaly can remove again the cholesterol on blood in human body in tube wall, prevention heart and brain nephro angiosclerosis prevention poliosis and Alopecia;Effect that Thallus Porphyrae also has resolving phlegm and softening hard masses, clearing away heat and promoting diuresis, the kidney invigorating are nourished heart;Nutritious, amount of iodine is the highest, can be used for controlling Treating " thyromegaly " caused because of iodine deficiency, Thallus Porphyrae has hard masses softening and resolving function, and other pent-up is amassed block also purposes;Rich in choline With calcium, ferrum, energy hypermnesis, treatment woman anemia, promotion skeleton, the growth of tooth and health care;Containing a certain amount of mannitol, Can be as the accesary foods for the treatment of edema;Polysaccharide contained by Thallus Porphyrae has and is remarkably reinforced cellular immunization and humoral immune function, can Promote lymphocyte transformation, improve the immunity of body;The total content into serum cholesterol can be significantly reduced;Effective one-tenth of Thallus Porphyrae Divide the suppression ratio 53.2% to ehrlich carcinoma, contribute to the preventing and treating of the tumors such as the cerebral tumor, breast carcinoma, thyroid carcinoma, malignant lymphoma.
Trophic analysis: (1) protein and the life active compound of aminoacid Thallus Porphyrae, the heaviest for plant vital activity Want.Edible laver general protein content 24%-28%, the most general vegetable, and necessary to human body, aminoacid contains Amount is many.Neutrality, the acidity such as the composition aminoacid of purple laver protein such as alanine, aspartic acid, glutamic acid, glycine, proline Aminoacid is more, and this is all unexistent features of terrestrial vegetable plant.
(2) fat is compared with terrestrial plant, and the fat content of Thallus Porphyrae is low, how below 1%, in the fat of Thallus Porphyrae, saturated The palmitic acid of fatty acid accounts for the overwhelming majority, and about 20%;The acid of lima bean Herba Alii fistulosi, stearic acid content is less, accounts for 2% respectively;Human body is had Very well unsaturated fatty acids linoleic acid, linolenic acid or the stearidonic acid content of health-care effect are more, are 10% 30%, And the highly unsaturated fatty acid of more than C20 also has certain content.More optimizedly Thallus Porphyrae is likened to " NAOHUANGJIN " by people Content of Eicosapentaenoic Acid be up to 30%.
(3) vitamin Thallus Porphyrae contains multivitamin, and the content of vitamin B group is not a halfpenny the worse compared with vegetable.B in Thallus Porphyrae The content of the vitamin B12 that vitamin particularly there's almost no in terrestrial plant is the highest, in terms of dry, and vitamin B12 Content with the flesh of fish close, ascorbic content is the highest.Vitamin B12 enlivens cranial nerve, and pre-anti-aging and memory declines Move back, improve effect of melancholia.
(4) inorganic composition that inanimate matter is extremely abundant owing to sea water contains, and Thallus Porphyrae has in absorption and savings sea water The function of inanimate matter, because the inanimate matter content in a little Thallus Porphyraes is the abundantest.
3.3, Thallus Laminariae (Thallus Eckloniae)
Thallus Laminariae (Thallus Eckloniae) contains the dimensions such as the multiple necessary protein of human body, aminoacid, proline, isoleucine, alanine, glycine Raw element B12 0.7ug%, B2 810mg% carotene 0.77%, water solublity potassium chloride, iodine, calcium, bromine, algin acid, laminaran, Mannitol, inorganic salt, organic acid, linolenic acid methanol, pohytol, Palmic acid, 24-ethylidenecholest-5-en-3.beta.-ol., sky bridle terpene, inner wheat straw lactone, polysaccharide Deng, pharmacology: thyroid function 1, can be corrected not enough;2, the absorption of pathological product (inflammation) exudate can be promoted;3, blood pressure lowering: sea The human body absorption to cholesterol can be reduced with propylhomoserin and potassium salt, calcium constituent, reduce blood pressure;4, antiasthmatic effect;5, replenish the calcium: Thallus Laminariae (Thallus Eckloniae) contains There is abundant calcium, human body calcium deficiency can be prevented and treated;6, beauty treatment: kelp juice can be with looks improving and the skin nourishing, and the decoction being boiled into Thallus Laminariae (Thallus Eckloniae) is bathed, permissible Moist skin, makes skin refreshing fine and smooth, bright and clean beauty;7, fat-reducing: Thallus Laminariae (Thallus Eckloniae) contains substantial amounts of dietary fiber, can increase overweight people Satiety, and Thallus Laminariae (Thallus Eckloniae) fat content is the lowest, and heat is little, is the food lost weight of overweight people;8, slow down aging: kelp Rich contains There is selenium, can effectively remove free radical, and the arch-criminal of free radical human senility just, so Thallus Laminariae (Thallus Eckloniae) can be with the work of slow down aging With.9, anticancer;Sodium alginate contained by Thallus Laminariae (Thallus Eckloniae) has the strongest binding ability with the tool strontium of carcinogenesis, cadmium, and by it Excrete;Thallus Laminariae (Thallus Eckloniae) alternative can produce carcinogenic antibacterial in killing or suppressing intestinal, and contained fiber can also promote Enter the discharge of bile acid and cholesterol;Thallus Laminariae (Thallus Eckloniae) extract has direct repression to various cancerous cell;10, radioprotective: Thallus Laminariae (Thallus Eckloniae) Extract laminarin has radiation resistance because of suppression immunocyte apoptosis;Modern medicine study confirms its extract algin Acid sodium has anastalsis, and pre-preventing leukemia, Itai-itai diseases, minimizing putting property element are by intestinal absorption.
4. Folium Mori
Folium Mori include one and are called 1-deoxidation open country mycin (DNJ), and this is a kind of a kind of alkaloid existed only in Folium Mori, Content about 100mg/100g, this alkaloid is the inhibitor of a kind of alpha-glucosidase.Folium Mori do not contain only DNJ, and contains Abundant gamma aminobutyric acid and plant are pure, and its content is 3-4 times of green tea.There is fat-reducing, beauty treatment, hypoglycemic effect.
It is nutritious, containing multivitamin and mineral, aminoacid, carbohydrate and Plant fiber.1993 Health ministry confirms: Folium Mori " integration of edible and medicinal herbs ".Folium Mori are first-class functional food, and its energy blood pressure lowering, blood fat reducing, defying age increase resistance to Power, reduction cholesterol, suppression Fat Accumulation, suppression thrombosis generate, and suppress intestinal toxic bacterial reproduction, suppress harmful oxide Generating, the most prominent function is to prevent and treat diabetes.There is cough-relieving, reduce phlegm and internal heat, treatment dizziness and blurred vision, eliminate eye strain, detumescence, clear Blood, treats dysentery, edema, tonifying liver, speckle dispelling, skin care, anti-ageing function of waiting for a long time.
There is reduction blood glucose effect: containing N-sugar compounds (N-containing-sugars) in Folium Mori, there is suppression blood The pharmacological action that sugar rises, can be used for preventing and treating and treating diabetes.[3] the Folium Mori original has the function that suppression blood glucose rises, its Major function composition is " alkaloid " in Folium Mori, and this is a kind of composition with specific function, and it is that other animal and plant are not had Have.Japan medical science circle claims this specific group to become " DNJ " material.Its Main Function is suppression saccharase, maltase, a-Portugal Grape sugar sweet sugar, the diastatic decomposition of a-, can stimulate insulin secretion, reduce insulin decomposition rate.[4]
There is the skin ulcer effect of dispelling spots that disappears: research proves, Folium Mori also have good beautifying skin effect, the particularly Cuo to face Skin ulcer, brown macules have reasonable curative effect.Folium Mori are rich in chromocor compound, phenols, aminoacid, organic acid, carotene, vitamin And the trace element of multiple needed by human, this is to improving and the metabolism of regulation of skin tissue, though suppressing pigmentation especially Generation and development all have positive role.Lipofuscin in skin or internal organs (i.e. senile plaque) also it is reduced it addition, adhere to often drinking Stagnant.
There is fat-reducing fat eliminating effect: Folium Mori tea can be lost weight, it is simply that " subside a swelling " with Folium Mori, the effect of " purifying the blood " relevant.Mulberry Why leaf tea can subside a swelling, and being because Folium Mori has the effect of diuretic.Diuretic effect is different from diuresis, not only can promote Urinate, it is also possible to make the excessive moisture amassing in cell drain.So Folium Mori tea can improve so-called edema phenomenon.Purify the blood and be Neutral fat superfluous in blood and cholesterol are cleared.Neutral fat or cholesterol increase in blood are exactly too much hyperlipidemia Disease.So fat people mostly is hyperlipidemia patient.Folium Mori have the effect improving this hyperlipidemia.
Have and reduce the viscous effect of blood: the blood viscosity of hyperlipemia patient is high, and the flowing in blood capillary is the most smooth Logical.Blood capillary only has the 1/100 so thick, so easily blocking of our hair.Myocardial infarction and cerebral hemorrhage are all blood capillarys The result of blockage.Containing strengthening blood capillary, the flavones ingredient of reduction blood viscosity in Folium Mori, so in fat-reducing, improving While hyperlipemia, there are again prevention myocardial infarction and the effect of cerebral hemorrhage.
Particularly Folium Mori after frost, its effect is more preferable, is found by hyperlipemia animal experiment, and Folium Mori have suppression serum lipid Matter increases and the effect of suppression atherogenesis.
Antiinflammatory, book on Chinese herbal medicine record Folium Mori have clearing away heat and expelling pathogen in the exterior effect, and modern study shows that Folium Mori have stronger antiinflammatory action, With dispel the wind, heat clearing away effect is consistent.
Defying age, the effect that Folium Mori have the tonification of similar Radix Ginseng and defying age, stablize nervous function, can alleviate and give birth to It is excited that reason change causes, and improves the activity of internal superoxide dismutase, stops the generation of internal harmful substance, minimizing Or eliminate the internal lipofuscin that produced and stagnated.Folium Mori can regulate the body respond to stress stimulation, enhancing body Tolerance and delaying senility function.
Antitumor, antiviral, filaricide etc. act on, and additionally Folium Mori are containing abundant cellulose, therefore have catharsis relieving constipation, guarantor Protect the effect of intestinal mucosa and fat-reducing.
The technical solution used in the present invention is as follows:
A kind of formula of Functional capsule, in terms of parts by weight, its component is:
Fuel 70-90 part that Abelmoschus esculentus, bacterium, algae, Folium Mori extract, mycelium 10-30 part;
The invention also discloses above-mentioned fuel formula: Abelmoschus esculentus 20-40 part, bacterium 15-35 part, algae 25-35 part, Folium Mori 10-20 part;Abelmoschus esculentus use green organic plantation Abelmoschus esculentus, bacterium use Cordyceps militaris (L.) Link., Hericium erinaceus (Bull. Ex Fr.) Pers., Poria, Ganoderma any one Or combination, algae uses any one or the combination of spirulina (spirulina maxim or spirulina plalensis), Thallus Porphyrae, Thallus Laminariae (Thallus Eckloniae);
Described mycelium is any one or the combination of Cordyceps militaris (L.) Link., Hericium erinaceus (Bull. Ex Fr.) Pers., Poria, Ganoderma.
The invention also discloses the preparation method of a kind of Functional capsule, comprise the steps:
A. prepared by fuel:
1) weighing Abelmoschus esculentus 20-40 part, bacterium 15-35 part, algae 15-30 part, Folium Mori 10-20 part, folder is put in the mixing of each raw material In layer pot, add the water of 50 times of weight, heated and boiled 4-6 hour, extract the stock solution after boiling;
2) residue after the extracted stock solution of step 1, hot water (hot water of the 80-95 DEG C) heating adding 3 times of residue weight is boiled Boiling liquid is extracted after boiling 4-6 hour;
3) being merged by above-mentioned secondary raffinate, 100 mesh filter, and filtrate is centrifuged (3500r/min/15 minute);
4) take the centrifugal supernatant of step 3, concentrated (being concentrated in vacuo) vacuum 8.38*10-4 handkerchief and concentrate, charging Concentrated solution concentration is 4-5%, is concentrated into 8%;
5) in the concentrated solution of the 8% of step 4, add adjuvant: 50% white sugar of concentrated solution weight and the dextrine powder of 1%, fill Point stirring even obtains compound;
6) compound of step 5 is spray-dried, feeding temperature 50-60 DEG C, high-pressure pump operating pressure 1.764*107 Handkerchief;Inlet temperature 120 degree, leaving air temp 75-78 DEG C, obtain fuel (standby) after cooling;
B. prepared by mycelium:
1) take Cordyceps militaris (L.) Link., Hericium erinaceus (Bull. Ex Fr.) Pers., Poria, Ganoderma any one, by after activated for the inclined-plane of strain at 25 DEG C ± 2 DEG C Under the conditions of carry out 1 grade, 2 grades of shake-flask culture (shaking speed 180 revs/min) are cultivated 4~6 days respectively;
2) being seeded in jar fermenter by above-listed expansion strain, (cylinder presses 0.05 MPa, ventilation ratio 1:0.8) is at 25 DEG C ± 2 DEG C Lower cultivation took out fermented product i.e. mycelium in cylinder after 3-4 days;
3) (standby) is dried by above-listed mycelium lyophilizing or below 60 DEG C;
C. prepared by capsule:
1) above-mentioned fuel 70-90 part is taken, the powder of mycelium 10-30 part co-grinding to 100 mesh fineness;
2) packaging, either manually or mechanically loads the material after above-mentioned pulverizing in capsule, every weight 0.3g, then by quantitative requirement Dress bottle/bag in/box in, i.e. obtain the finished product with functional capsule after sterilizing.
The invention have the advantage that 1. selections have plant certain function, medicine-food two-purpose;2. with water hot extraction/extraction These effective ingredient are formed by the effective ingredient in various article according to the theoretical basis of Chinese medicine and pharmacy and modern medicine;3. exist On the basis of having applied for a patent drink/food, further processed, make Functional capsule, be so easy to carry, more convenient Drink-service, and can take according to quantity according to its effect;4. improve sub-health state by daily taking, prevent or treat or assist treatment Some disease;5. the formula of the present invention the most easily takes, preparation technology science, advanced person, can be mass, manufactured goods effective ingredient Height, can take as the ancillary drug of some disease or health-care tonic official ceremonial dress use, has treatment and prevention disease and reinforcement The function of matter.
Below in conjunction with embodiment, the present invention is further described.
Detailed description of the invention
Embodiment: the formula of a kind of Functional capsule, in terms of parts by weight, its component is: Abelmoschus esculentus, bacterium, algae, Folium Mori carry The fuel 70-90 part taken, mycelium 10-30 part;
The present embodiment also discloses above-mentioned fuel formula: Abelmoschus esculentus 20-40 part, bacterium 15-35 part, algae 25-35 part, Mulberry Leaf 10-20 part;Abelmoschus esculentus uses the Abelmoschus esculentus of green organic plantation, and the bacterium that the present embodiment is selected uses Hericium erinaceus (Bull. Ex Fr.) Pers., it is possible to select Cordyceps militaris (L.) Link., Poria, any one or the combination of Ganoderma, the algae that the present embodiment is selected is Thallus Laminariae (Thallus Eckloniae), it is possible to use spirulina (very big spiral Algae or spirulina plalensis), any one or the combination of Thallus Porphyrae;
The mycelium that the present embodiment is selected is Cordyceps militaris (L.) Link., it is also possible to select any one or the group of Hericium erinaceus (Bull. Ex Fr.) Pers., Poria, Ganoderma Close.
The present embodiment also discloses the preparation method of a kind of Functional capsule, comprises the steps:
A. prepared by fuel:
1) weighing Abelmoschus esculentus 20-40 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 15-35 part, Thallus Laminariae (Thallus Eckloniae) 15-30 part, Folium Mori 10-20 part, each raw material mixes Put into jacketed pan, add the water of 50 times of weight, heated and boiled 4-6 hour, extract the stock solution after boiling;
2) residue after the extracted stock solution of step 1, hot water (hot water of the 80-95 DEG C) heating adding 3 times of residue weight is boiled Boiling liquid is extracted after boiling 4-6 hour;
3) being merged by above-mentioned secondary raffinate, 100 mesh filter, and filtrate is centrifuged (3500r/min/15 minute);
4) take the centrifugal supernatant of step 3, concentrated (being concentrated in vacuo) vacuum 8.38*10-4 handkerchief and concentrate, charging Concentrated solution concentration is 4-5%, is concentrated into 8%;
5) in the concentrated solution of the 8% of step 4, add adjuvant: 50% white sugar of concentrated solution weight and the dextrine powder of 1%, fill Point stirring even obtains compound;
6) compound of step 5 is spray-dried, feeding temperature 50-60 DEG C, high-pressure pump operating pressure 1.764*107 Handkerchief;Inlet temperature 120 degree, leaving air temp 75-78 DEG C, obtain fuel (standby) after cooling;
B. prepared by mycelium:
1) take Cordyceps militaris (L.) Link. 100g, it is possible to select Hericium erinaceus (Bull. Ex Fr.) Pers., Poria, Ganoderma any one, by the strain of Cordyceps militaris (L.) Link. through inclined-plane Activation, the key points for operation of inclined-plane preparation and actication of culture are as follows: 1. press glucose 0.1%, Carnis Bovis seu Bubali cream 1%, peptone 1%, chlorine Change sodium 0.5%, agar 2%, water proportioning, bevel culture medium (agar is with temperature height increase and decrease);2. pass on every, inclined-plane 18 × 180 test tubes, about loading amount 10ml, every, production inclined-plane 25 × 200 test tubes, about loading amount 25ml, it is cooled to after sterilizing 55~65 DEG C, spread out into inclined-plane, under conditions of 25 DEG C ± 2 DEG C, carry out 1 grade, 2 grades of shake-flask culture (shaking speed 180 revs/min) point Pei Yang 4~6 days;
2) being seeded in jar fermenter by above-listed expansion strain, (cylinder presses 0.05 MPa, ventilation ratio 1:0.8) is at 25 DEG C ± 2 DEG C Lower cultivation took out fermented product i.e. mycelium in cylinder after 3-4 days;
3) (standby) is dried by above-listed mycelium lyophilizing or below 60 DEG C;
C. prepared by capsule:
1) above-mentioned fuel 70-90 part is taken, the powder of mycelium 10-30 part co-grinding to 100 mesh fineness;
2) packaging, either manually or mechanically loads the material after above-mentioned pulverizing in capsule, every weight 0.3g, then by quantitative requirement Dress bottle/bag in/box in, i.e. obtain the finished product with functional capsule after sterilizing.
Configure according to food therapy function according to the overview of digesting and assimilating of human body;Its consumption is accurate, and effect is obvious, it is simple to take, The function having: improve immunity, stamina intensifying, muscle power, blood pressure lowering, blood fat reducing, antiinflammatory, analgesia etc..
The traditional Chinese medical science, when dialectical treating, pays much attention to consumption.To different diseases, the most same disease of different patients not Same patient, though using same medicine, but its quantity is different, even has a long way to go;Quantity is crucial, this be also us The result obtained explored by the research functional food of tens of loads.
The relevant research of the beverage that the present invention obtains and experiment: complete acute toxicity testing " 50LD " and Ames experiment The clinical observation of zoopery and volunteer is carried out on the premise of having no side effect.Every test result is as follows:
1. method
The functional capsule of the present invention, the quantity grasped by practice, proportioning example, technique etc., mixing is made various forms of And there is the food of function.
Zoopery
(1) resisting fatigue experiment
A: swimming test: take the white mice 30 of body weight 20-25 gram, be randomly divided into 2 groups, first group feeds general food and (makees Comparison): second group feeds (food, the water) containing 5% functional capsule, and twice daily, every Mus feeding product 2 grams every time, water 3ML is continuous After 20 days, being put into the most respectively in water vat by 2 groups of white mice, their swimming time of observed and recorded, result is as shown in the table:
White mice resisting fatigue contrast test table 2
Feed natural law First group (average minute) Second group (average minute)
1 8.2 8.1
3 8.3 8.4
5 8.4 8.6
7 8.0 8.8
9 8.3 8.7
15 8.2 9.4
20 8.2 10.6
As seen from Table 2, feeding in 1-3 days, the swimming time of 2 groups of mices is close, without much differences, during by the 7th day, feeds The swimming time of the second group mice of functional capsule (food, water) than matched group many 0.5 minute, extends (increasing) to when 20 days 2.4 minute.Their long trend of prolonging is gradually increased, the most simultaneously.This show functional capsule have delay tired The effect of labor.
B: pole-climbing (ability) is tested: the first and second 2 groups of mices are placed in rotary speed 16 revs/min, the wooden circle of diameter 2.5CM On bar, observing the time that they are creeped on bar, result is as follows:
White mice ability contrast test table 3
Feed natural law First group (average minute) Second group (average minute)
1 28 25
3 29 28
5 30 31
7 32 35
9 33 38
11 44 54
15 43 58
20 44 65
As seen from Table 3, feeding at the beginning of the beginning, 2 groups of Endurances are close, and from the 7th day, the pole-climbing ability of second group mice gradually added By force, extending 21 minutes to according to group to when the 20th day, this shows that solid drinks can make the endurance of mice strengthen.Meanwhile, Zoopery is also pointed out, and solid drinks needs continuous longer-term to take, and short-term drinks DeGrain.
C: high-low temperature resistant is tested: takes male 6 weeks healthy mices 30, every body weight 21 ± 2g, is randomly divided into 2 groups, often Organizing 15 is one group, feeds every day and is respectively as follows:
1 group: feed 5ml/22g (drinking water) body weight+feedstuff 2g (matched group) every day;
2 groups: feed the food 2g (functional capsule containing 10% functional capsule 5ml/22g body weight+containing 10% functional capsule every day Group);
Functional capsule affects table 4 to white mice high/low temperature swimming time
* P < 0.05, P < 0.01
Experimental result: functional capsule group is in 43 degree of water went swimming prolonged survival period 199.22% (P < 0.01), at 8 degree Water went swimming time lengthening 73.50% (P < 0.01).This shows that functional capsule can significantly improve mice at 43 degree, quilt in 8 degree of water Moving the time-to-live of swimming and in dose-effect relationship, prompting has obvious emergency capability and dynamic endurance.
D, improve the effect of body gastrointestinal function: take male and healthy white mice 30, be randomly divided into 2 groups, often group 15, often It feeds and is respectively as follows:
1 group: feed normal saline 0.5ML/21g+ normal diet (matched group) every day
2 groups: feed the commensurability food containing functional capsule 15% every day;Feed continuously 8 days, fasting 24 hours in the 9th day, the Within 10 days, feed after above-listed various beverage/food 25 minutes, then gavage black carbon meal (5% activated carbon, 1.2% agar) 0.5ML/21g Body weight, after 15 minutes, cervical dislocation puts to death mice, and careful taking-up Mouse Stomach cardia, to one section of digestive tract of rectum end, without leading Drawing on Horizon flooring, measure the distance (A) of this section of digestive tract total length and the cardia distance (B) to carbon dust end, statistics is every Percentage rate=B/A*100% that group mice carbon dust moves at digestive tract, result is as shown in the table:
Functional capsule affects table 5 to enterogastric peristalsis
Group Carbon meal mobility (%) Increase percentage rate (%)
Normal saline group 35.39±3.87 -------
Functional capsule group 59.85±4.48 69.12
Test result indicate that: functional capsule is obviously promoted enterogastric peristalsis, the mobile increment rate of carbon meal is up to 69.12%, P < 0.05, significant difference, and have obvious dose-effect relationship.
E, immunization experiment: burn mice lower limb abdominal part, the gross area about 35% with alcohol burner, the degree of depth is 5% II+wound, feeds every day Food containing 20% functional capsule 4, every 0.25g and containing 20% functional capsule 6ml, and with this beverage by functional food furnishing Pasty state, is coated with abrasion, observes wound healing situation and detects the items such as hemolysin, lymphocyte transformation.Result: feeding function and drink The mice wound healing of material is fast, and hemolysin, lymphocyte etc. all have improvement.
SOD value in F, detection blood: taking (14 months) of the same age, body weight, the mice totally 20 of 25-28 gram, is randomly divided into 2 Group, A group feeds normal food, water, and B group feeds the food containing functional capsule 25% and water, takes their blood after continuous 90 days, inspection Surveying wherein SOD activity, in result B group blood, SOD specific activity A group averagely increases by 8.4 active units.
G, memory reinforcing are tested: passed through by A group (feeding normal food) B group (feeding the above-mentioned food containing functional capsule) mice The overhead lost experiment of cross, the experiment of shuttle box behavior carries out systematic observation rear surface, and the memory of B group Mus has substantially than A group Raising.
It is demonstrated experimentally that the functional capsule made with Abelmoschus esculentus, algae, bacterium, Folium Mori, have significantly suppression malonaldehyde generation and The effect of monoamine oxidase A, can increase the activity of SOD, improves immunity and increases erythrocyte number;Promote gastrointestinal peristalsis;Improve Anoxia enduring power, muscle strength reinforcing and endurance;Added body (power) energy and body fluid, strengthen the repair of wound.
2. human body practice/application test
On the basis of animal experiment obtains significantly, after elder generation, the interruption through 50 volunteers in ground such as Jiangsu, Shanghai, Anhui takes Food is on probation, and their body constitution has improvement in various degree, raising.Especially with athlete in fierce (training) match, Under the state of fever, metabolism accelerator produces the gene free radical of a kind of great strong Oxidation.? When intracellular free radicals exceedes some, human body is produced impact and damage.It makes cell membrane degeneration, rotten, makes heredity letter Breath makes a mistake, and makes protein lose due biological function (tired) etc. and destroy rule (the internal lactic acid of substance metabolism Assemble).
A, tired aching pain of muscles recover (disappearance) experiment: each for men and women 10 athletes are randomly divided into experimental group and add 10g functional capsule, matched group is refused to obey functional capsule, is observed, compares tired (aching pain of muscles) recovery (disappearance) after their training Degree and athletic feel, use accumulation scoring method.The standard that accumulation is scored:
A, after 24 hours, fatigue is wholly absent, and muscle does not has obvious ache 5 points
B, after 24 hours, tired basic recovering, ache alleviates a lot of 4 points
C, after 24 hours, still some tired and ache, but the most serious 3 points
D, after 24 hours, still feeling tired, aching pain of muscles slightly extenuates 2 points
E, after 24 hours, tired, aching pain of muscles does not disappear, and maintains the original state 1 point
It is observed that, compare 14 days after result such as following table: table 6
Improvement rate 30% 50% 60%
Beverage group (%) 37 22 89
Matched group (%) 32 13 52
As seen from Table 6, disappearance tired after einnehmen function capsule and aching pain of muscles extenuate degree, the most relatively refuse to obey function drink The rate that is clearly better of material is higher.
The change of SOD content in B, blood: try clothes through 16 volunteers, three times a day, each take functional capsule 10g, After continuous 3 months, detect their SOD content, 18.84 units before taking product increase to 34.68 units;The formal name used at school of SOD Being superoxide dismutase, it is a kind of active substance coming from life entity and defying age enzyme, can protect cell not by internal " oneself By base " infringement.When it meets with free radical, free radical is promoted to be decomposed into harmless hydrone and oxygen molecule.Root According to Long-Term Scientific Study, find that the physiological function of SOD mainly has: improve body immunity, slow down aging;It is effectively reduced blood Diabetes are had obvious restitution, have expert to claim: the content of the SOD in human body and the life-span of its people by glutinous, blood pressure and blood glucose Being directly proportional, SOD has become the health care gold of 21 century.
C, erythrocytic change: erythrocyte is one of main visible component of blood, is made up of hemoglobin and water, it is put down All life-spans are 90-120 days.Erythrocyte is dead or after destroying, and hemoglobin is by the phagocytosis of liver, spleen, bone marrow etc. and is decomposed into Globulin and iron content haemachrome.Ferrum is separated out by iron content haemachrome, becomes bilirubin, and making blood plasma is yellow.
Erythrocyte number: normal male is 400 500 ten thousand/MM
Normal female is 350--500 ten thousand/MM
Be engaged in intense physical activity or excited time, internal RBC number there will be the raising of transience.Blood red egg Being to constitute erythrocytic main component in vain, erythrocytic main Physiological Function is completed by hemoglobin.Through 14 volunteers (8 male 6 female) einnehmen function capsule 20 grams continuously is after 45 days, and their erythrocyte number occurs to change as follows:
Erythrocytic number change contrast table 7
Hemoglobin is fully combined with oxygen, forms oxygenated haemoglobin.This kind of hemoglobin is mainly in arterial blood.When Arterial blood circulation is in histoorgan, and hemoglobin and oxygen separating, histoorgan cell obtains oxygen and carries out metabolism.The most blood red egg Leucismus is reduced hemoglobin, carries CO2 external with breathing eliminating.
Blood pH can also be played cushioning effect by hemoglobin, keeps stablizing of human internal environment.Therefore, prompting merit Can have the erythrocytic effect of enhancement for beverage, internal gas exchange acid-base balance etc. is all had positive meaning.
Athlete's physical demands when training (containing match) has certain boundary, and this boundary is again by two kinds of factors Restriction: one is the reduction of blood sugar concentration;Two are because perspiring, the loss of body fluid and cause the unbalance of electrolyte.This certainly the most again with Muscle power (training) intensity of consumption is relevant with environment temperature.But blood sugar concentration can be made during carbohydrate supplementation to raise, islets of langerhans Element level improves, and makes the storage direction of glycogen adjust again, but the liquid supplemented is unabsorbable in stomach, can only pass through Pylorus could be absorbed in intestinal.Stomach (pylorus) is normally closed, and its opening and closing is by the domination of gastric food (instinct).Typically In the case of gastric food osmotic pressure the lowest, the fastest to the speed of bowel movement, water and the carbohydrate speed from stomach to intestinal be limit The principal element of supplemental amount processed.
The most nutritious equilibrium of functional capsule, but also contain Abelmoschus esculentus, algae, bacterium and Folium Mori class polysaccharide etc. uniquely (this kind of material is better than monosaccharide-glucose, fructose etc.) and appropriate inorganic salt and trace element, vitamin etc. can be supplemented because of big Measuring the inorganic salt and other material of antiperspirant loss, its osmotic pressure is the lowest simultaneously, can enter intestinal quickly through stomach, be absorbed as soon as possible, from And supplement physical consumption.
Experiment shows, athlete be in " during geo-stationary (not training and competition) state, i.e. motion before blood glucose (averagely contain Amount is 4.2 ± 3mg/L, and from the beginning of (movable) is trained, blood glucose is just gradually increasing, and rises to 22 ± 2mg/L to blood glucose when 45 minutes, Reach peak, the most gradually decline, until at the end of (movable) training, blood glucose remains between 9--11mg/L, the highest Level before (movable) is trained.Original (not having activity, during training) can be returned to after 2 hours again through (geo-stationary) Level, its result is as shown in the table:
The change of blood sugar contrast table 8 of the motion person of seesawing
The present invention is application heating abstraction technique, and the various effective ingredient in formula are organically combined the merit obtained Energy capsule, effective benefit materials content is high and makes good use of, and can improve sub-health state by daily taking, prevents or pass through Take and treat or assist some disease for the treatment of.Inventive formulation the most easily takes, preparation technology science, advanced person, can be mass, Manufactured goods effective ingredient is high, can be used as dietetic therapy product and also can take as tonic, can treat and prevent the function of disease.

Claims (1)

1. a preparation method for Functional capsule, raw material its component in terms of parts by weight is:
Fuel 70-90 part that Abelmoschus esculentus, bacterium, algae, Folium Mori extract, mycelium 10-30 part;
Described fuel formula is: Abelmoschus esculentus 20-40 part, bacterium 15-35 part, algae 25-35 part, Folium Mori 10-20 part;Abelmoschus esculentus is adopted With the Abelmoschus esculentus of green organic plantation, described bacterium uses Cordyceps militaris (L.) Link., described algae to use spirulina maxim;
Described mycelium uses Cordyceps militaris (L.) Link. to cultivate;
Realize the preparation method of this Functional capsule, comprise the steps:
A. prepared by fuel:
1) weighing the Abelmoschus esculentus of formula ratio, bacterium, algae, Folium Mori, the mixing of each raw material is put into jacketed pan, is added the water of 50 times of weight, add Heat is boiled 4-6 hour, extracts the stock solution after boiling;
2) residue after the extracted stock solution of step 1, adds the hot water of 80-95 DEG C of 3 times of residue weight, heated and boiled 4-6 hour Rear extraction boiling liquid;
3) being merged by above-mentioned secondary raffinate, 100 mesh filter, and filtrate is centrifuged, and are centrifuged and are set to 3500r/min, 15 minutes;
4) take the centrifugal supernatant of step 3, be concentrated in vacuo, vacuum 8.38 × 10-4Handkerchief concentrates, and feeds concentrated solution concentration For 4-5%, it is concentrated into 8%;
5) in the concentrated solution of the 8% of step 4, add adjuvant: 50% white sugar of concentrated solution weight and the dextrine powder of 1%, fully stir Mix thoroughly and obtain compound;
6) compound of step 5 is spray-dried, feeding temperature 50-60 DEG C, high-pressure pump operating pressure 1.764 × 107Handkerchief; Inlet temperature 120 DEG C, leaving air temp 75-78 DEG C, obtain fuel after cooling;
B. prepared by mycelium:
1) take Cordyceps militaris (L.) Link. appropriate, after activated for the inclined-plane of strain, under conditions of 25 DEG C ± 2 DEG C, carry out 1 grade, 2 grades of shaking flask trainings Support, shaking speed 180 revs/min, cultivate 4~6 days respectively;
2) being seeded in jar fermenter by above-listed expansion strain, cylinder presses 0.05 MPa, ventilation ratio 1:0.8, cultivates at 25 DEG C ± 2 DEG C Fermented product i.e. mycelium in cylinder is taken out after 3-4 days;
3) dry by above-listed mycelium lyophilizing or below 60 DEG C;
C. prepared by capsule:
1) above-mentioned fuel 70-90 part is taken, the powder of mycelium 10-30 part co-grinding to 100 mesh fineness;
2) packaging, either manually or mechanically loads the material after above-mentioned pulverizing in capsule, every weight 0.3g, then fills by quantitative requirement In bottle/bag/box in, i.e. obtain the finished product with functional capsule after sterilizing.
CN201410572517.8A 2014-10-23 2014-10-23 Functional capsule and preparation method thereof Expired - Fee Related CN104382007B (en)

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