CN106947791B - 一种利用生物酶催化合成阿扎那韦中间体氯醇的方法 - Google Patents
一种利用生物酶催化合成阿扎那韦中间体氯醇的方法 Download PDFInfo
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- CN106947791B CN106947791B CN201710149643.6A CN201710149643A CN106947791B CN 106947791 B CN106947791 B CN 106947791B CN 201710149643 A CN201710149643 A CN 201710149643A CN 106947791 B CN106947791 B CN 106947791B
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- chloroketone
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
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CN201710149643.6A CN106947791B (zh) | 2017-03-14 | 2017-03-14 | 一种利用生物酶催化合成阿扎那韦中间体氯醇的方法 |
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CN201710149643.6A CN106947791B (zh) | 2017-03-14 | 2017-03-14 | 一种利用生物酶催化合成阿扎那韦中间体氯醇的方法 |
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CN106947791A CN106947791A (zh) | 2017-07-14 |
CN106947791B true CN106947791B (zh) | 2021-05-04 |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102482648A (zh) * | 2009-06-22 | 2012-05-30 | 科德克希思公司 | 酮还原酶介导的产生α氯代醇的立体选择性途径 |
CN102876733A (zh) * | 2012-10-23 | 2013-01-16 | 凯莱英医药集团(天津)股份有限公司 | 一种制备高光学纯度的醇类化合物的方法 |
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2017
- 2017-03-14 CN CN201710149643.6A patent/CN106947791B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102482648A (zh) * | 2009-06-22 | 2012-05-30 | 科德克希思公司 | 酮还原酶介导的产生α氯代醇的立体选择性途径 |
CN102876733A (zh) * | 2012-10-23 | 2013-01-16 | 凯莱英医药集团(天津)股份有限公司 | 一种制备高光学纯度的醇类化合物的方法 |
Non-Patent Citations (1)
Title |
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生物酶催化不对称合成阿扎那韦中间体;刘念;《2013年中国化学会产学研合作研讨会会议论文集》;20131026;第65页第1段 * |
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Effective date of registration: 20200331 Address after: 646121 Lingang Economic Park, Luxian Economic Development Zone, Luzhou City, Sichuan Province Applicant after: SICHUAN QIGEMAN PHARMACEUTICAL Co.,Ltd. Address before: 646102 hundred towns, Luzhou, Sichuan, Luxian County Applicant before: LUZHOU RUIXING BIOENGINEERING Co.,Ltd. |
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Denomination of invention: A method for the synthesis of chlorohydrin, an intermediate of Atazanavir, catalyzed by biological enzyme Effective date of registration: 20230705 Granted publication date: 20210504 Pledgee: Luxian County Agriculture and Small and Medium sized Enterprise Financing Guarantee Co.,Ltd. Pledgor: SICHUAN QIGEMAN PHARMACEUTICAL Co.,Ltd. Registration number: Y2023980047484 |