CN106924628A - For Chinese medicine composition for improving the health care of sleep and preparation method thereof - Google Patents
For Chinese medicine composition for improving the health care of sleep and preparation method thereof Download PDFInfo
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- CN106924628A CN106924628A CN201710234703.4A CN201710234703A CN106924628A CN 106924628 A CN106924628 A CN 106924628A CN 201710234703 A CN201710234703 A CN 201710234703A CN 106924628 A CN106924628 A CN 106924628A
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- chinese medicine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The present invention provides a kind of for Chinese medicine composition for improving the health care of sleep and preparation method thereof, belongs to technical field of traditional Chinese medicine.The medicine long-term taking for solving existing treatment insomnia can produce drug resistance, dependence and insalubrious problem.The Chinese medicine composition in parts by weight, is made up of following bulk drug：29 33 parts of spina date seed, 29 33 parts of oyster, 14 18 parts of lily, 8 12 parts of lotus seeds, 48 parts of fructus alpiniae oxyphyllae, 48 parts of lophatherum gracile.The present invention also provides a kind of preparation method of the Chinese medicine composition for improving the health care of sleep.The Chinese medicine composition all the components are all the traditional Chinese medicine ingredients of integration of drinking and medicinal herbs, all it is usually edible, tonic, the food materials of health, there is positive improvement result to various types of sleep-disorder, can significantly improve due to worrying beyond measure, it is a tax on one's mind caused by wake up after the problem that feels fatigue, the equilibrium between yin and yang of body can be adjusted.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine, and in particular to a kind of Chinese medicine composition for improving the health care of sleep and its
Preparation method.
Background technology
The insomnia traditional Chinese medical science referred to as " is insomnia ", often many factors influence, multiple internal organs comprehensive functions such as the heart, liver,spleen,kidney
As a result, it is desirable to carry out deep, comprehensive diagnosis and treatment based on an overall analysis of the illness and the patient's condition.One is to cut off external drying factor as far as possible, and two is to be truly realized " to cure the disease
Must ask in this ", plurality of Chinese organic compatibility, based on antitoxic heart-soothing and sedative, nourishing and suppressing Yang, and comprehensive function is in the heart, spleen, liver, kidney etc.
Related internal organs, the inherent root for cause insomnia is nursed one's health.The Western medicine for being used to improve the health care of sleep in the prior art mainly has benzene
Diazepine, barbiturates etc., long-term use easily produce drug resistance and dependence, withrawal symptom easily occur.If suddenly
Be discontinued, it may appear that body is weak, appetite is poor, anxious, body weight falls sharply, tachycardia, dizziness, drop in blood pressure, emotional lability,
The diseases such as exciting irritability.Cardiopulmonary have the side effect for suppressing respiratory center in various degree.But the function of many Western medicine is also constantly more
Newly.It is existing also to have many kinds for improving the Chinese patent drug of insomnia, it is most of all containing the red sage root, the fruit of Chinese magnoliavine, vine of multiflower knotweed etc., these
The composition of Chinese patent drug is all not belonging to integration of drinking and medicinal herbs class Chinese medicine, belongs to medicine class, and taking for a long time to body also has certain injury.
The content of the invention
Medicine long-term taking the invention aims to solve existing treatment insomnia can produce drug resistance, dependence
And insalubrious problem, and provide a kind of for Chinese medicine composition for improving the health care of sleep and preparation method thereof.
Present invention firstly provides a kind of Chinese medicine composition for improving the health care of sleep, the Chinese medicine composition is according to parts by weight
Meter, is made up of following bulk drug：
Spina date seed 29-33 parts, oyster 29-33 parts, lily 14-18 parts, lotus seeds 8-12 parts, fructus alpiniae oxyphyllae 4-8 parts, lophatherum gracile 4-
8 parts.
Preferably, the described Chinese medicine composition for improving the health care of sleep, the Chinese medicine composition in parts by weight, by
Following bulk drug is made：
31 parts of spina date seed, 31 parts of oyster, 16 parts of lily, 10 parts of lotus seeds, 6 parts of fructus alpiniae oxyphyllae, 6 parts of lophatherum gracile.
The present invention also provides a kind of preparation method of the Chinese medicine composition for improving the health care of sleep, and the method includes：
Step one：Spina date seed, oyster, lily, lotus seeds, fructus alpiniae oxyphyllae and lophatherum gracile are cleaned, is mixed, obtain mixture；
Step 2：The mixture that step one is obtained is extracted twice at 90-95 DEG C, each 2.5h, then with 300 mesh mistakes
Filter, obtains extract solution；
Step 3：Step 2 is obtained into extract solution to be concentrated under reduced pressure at 55-65 DEG C, by concentrate drying and screening, in obtaining
Drug composition.
Pharmacological action of the invention is as follows：
Spina date seed：It is sweet, sour, mild-natured, Return liver, courage, the heart channel of Hang-Shaoyin.With tonifying liver, calming heart, arrest sweating, the effect promoted the production of body fluid, contained master
Composition is wanted for jujuboside, flavonoid glycoside, with tranquilizing soporific, anticonvulsion, analgesia, step-down, antiarrhythmic effect, Yi Jizeng
Effect of strong immunity.
Raw oyster：Nature and flavor：It is salty, cool, transquilization with heavy material, checking exuberance of yang tonifying yin, softening and resolving hard mass；With calm, anticonvulsant action, and have
Obvious analgesic activity.
Lily：Nature and flavor：Sweet, slight bitter, it is slightly cold, with Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing effect, for treating yin chronic cough, phlegm
It is middle with blood, pyreticosis later stage, waste heat be not clear or the disease such as dysphoria palpitates with fear, insomnia and dreamful sleep, absent-minded, wet sore caused by feelings will is unsuccessful.
Lotus seeds：Nature and flavor：It is sweet, puckery, flat, it is insufficiency of the spleen for treating the effect of with tonifying spleen and stopping diarrhea, supplementing the kidney to control the nocturnal, mental-tranquilization
Chronic diarrhea, protracted dysentery, emission due to the kidney deficiency, lingering diarrhea, urinary incontinence, married woman's uterine bleeding under band are rushed down, have no peace of mind, palpitate with fear, the illness such as egersis.
Fructus alpiniae oxyphyllae：There is gentle tonifying kidney and strengthening yang, astringent sperm contracting urine, warming spleen and stopping diarrha, raising memory.
Lophatherum gracile：Allayed excitement effect with clearing heart fire.
A kind of Chinese medicine composition for improving the health care of sleep of the invention, can add conventional pharmaceutic adjuvant and be made and pharmaceutically may be used
The oral formulations of receiving such as decoction, pill, capsule or granule etc., and the decoction, pill, capsule or granule
It is obtained using the customary preparation methods of corresponding species preparation.
Beneficial effects of the present invention
The present invention provides a kind of Chinese medicine composition for improving the health care of sleep, and the Chinese medicine composition is treated both principal and secondary aspect of disease, that is, is conceived to
Calm the nerves and take stopgap measures, calming heart, nourishing and suppressing Yang and taste, regulation hepatic and renal function are puted forth effort again to effect a permanent cure；Can with tonifying heart and spleen, mental-tranquilization,
The effective regulation heart, spleen, the function of liver：By nourishing and suppressing Yang, restoring normal coordination between heart and kidney makes up a deficiency, reducing for the excess syndrome, realizes that negative and positive are adjusted
With；Meanwhile, Chinese medicine composition of the invention is a kind of pure Chinese medicine composition of use integration of drinking and medicinal herbs, and all the components are all integration of drinking and medicinal herbs
Traditional Chinese medicine ingredients, be all usually edible, tonic, the food materials of health, have positive changing to various types of sleep-disorder
Kind effect, can significantly improve due to worrying beyond measure, it is a tax on one's mind caused by wake up after the problem that feels fatigue, the moon of body can be adjusted
Rising tone weighs, so the Chinese medicine composition does not have drug resistance, dependence and withrawal symptom.
Chinese medicine composition of the invention is used in 102 trouble of clinical observation insomnia in 2012 to 2016 and poor sleeping quality
Person, clinical report is as follows：
1st, clinical data
In this group 102, man 44, female 58, the age is minimum 17 years old, and maximum 58 years old, the course of disease was at 3 months to 4 years.
2nd, criterion of therapeutical effect
It is effective：Insomnia disappears, and patient sleeps' mass is good, and brains is clear, hypermnesia, and the insomnia recurrence intermittent phase prolongs
It is long.
Effectively：Insomnia substantially mitigates, patient sleeps' Quality advance, insomnia recurrence intermittent phase extension.
It is invalid：, without substantially mitigation, poor sleeping quality is dizzy, decrease of memory, without bright between insomnia recurrence for insomnia
Aobvious extension.
3rd, treatment method
Routinely technique is made tablet (500mg), three times per day, one time four, surrounding be a course for the treatment of.
4th, treatment results
In 102 patients, 53 (51.96%) in effect is significant ground, effective 48 (47.05%), invalid 1
(0.99%), total effective rate 99.01%.
5th, model case
Case 1：
Chen, female, 49 years old, disease more than a year, dysphoria and insomnia, a nearly month aggravation can not fall asleep all night, irritated many
Anger, spontaneous perspiration, brothers are scorching hot.Through the agent of calmness of being calmed the nerves with Chinese and Western, all do not produce effects.Look into its complexion not allowing, One's spirits are drooping, readme can not
Fall asleep, to night then irritated difficult dormancy.Tongue light HongShaoJin(SIC) is without tongue, wiry and frequent pulse.After taking the present invention one course for the treatment of of treatment, dysphoria and insomnia is received
Effect, the night stable sleep of energy, all diseases disappear and heal.
Case 2:
It is high so-and-so, man, 42 years old.Insomnia 3 years, dizzy all day, memory loss, then dreaminess of sleeping is diverse and confused, very then all night not
Sleep, absent-minded, red tongue with thin fur, the thin string of arteries and veins.Present invention treatment two weeks is taken, sleep is returned to normal.
Specific embodiment
Form, is described in further detail again to the above of the invention by the following examples, but should not be by this
The scope for being interpreted as this bright above-mentioned theme is only limitted to following example, all technologies realized based on the above of the present invention,
Belong to the scope of the present invention.
Embodiment 1
Raw material (gram) is weighed by following weight ratio：
29 grams of spina date seed, 29 grams of oyster, 14 grams of lily, 8 grams of lotus seeds, 4 grams of fructus alpiniae oxyphyllae, 4 grams of lophatherum gracile.
Step one：According to above-mentioned formula, spina date seed, oyster, lily, lotus seeds, fructus alpiniae oxyphyllae and lophatherum gracile are cleaned, mix,
Obtain mixture；
Step 2：The mixture that step one is obtained is extracted twice at 90 DEG C, each 2.5h, is then filtered with 300 mesh,
Obtain extract solution；
Step 3：Step 2 is obtained into extract solution to be concentrated under reduced pressure at 55 DEG C, 80 mesh sieving after concentrate is spray-dried,
Obtain Chinese medicine composition.
Embodiment 2
Raw material (gram) is weighed by following weight ratio：
33 grams of spina date seed, 33 grams of oyster, 18 grams of lily, 12 grams of lotus seeds, 8 grams of fructus alpiniae oxyphyllae, 8 grams of lophatherum gracile.
Step one：According to above-mentioned formula, spina date seed, oyster, lily, lotus seeds, fructus alpiniae oxyphyllae and lophatherum gracile are cleaned, mix,
Obtain mixture；
Step 2：The mixture that step one is obtained is extracted twice at 95 DEG C, each 2.5h, is then filtered with 300 mesh,
Obtain extract solution；
Step 3：Step 2 is obtained into extract solution to be concentrated under reduced pressure at 65 DEG C, 80 mesh sieving after concentrate is spray-dried,
Obtain Chinese medicine composition.
Embodiment 3
Raw material (gram) is weighed by following weight ratio：
31 grams of spina date seed, 31 grams of oyster, 16 grams of lily, 10 grams of lotus seeds, 6 grams of fructus alpiniae oxyphyllae, 6 grams of lophatherum gracile.
Step one：According to above-mentioned formula, spina date seed, oyster, lily, lotus seeds, fructus alpiniae oxyphyllae and lophatherum gracile are cleaned, mix,
Obtain mixture；
Step 2：The mixture that step one is obtained is extracted twice at 92 DEG C, each 2.5h, is then filtered with 300 mesh,
Obtain extract solution；
Step 3：Step 2 is obtained into extract solution to be concentrated under reduced pressure at 60 DEG C, 80 mesh sieving after concentrate is spray-dried,
Obtain Chinese medicine composition.
Claims (3)
1. a kind of Chinese medicine composition for improving the health care of sleep, it is characterised in that the Chinese medicine composition in parts by weight, by with
Lower bulk drug is made：
Spina date seed 29-33 parts, oyster 29-33 parts, lily 14-18 parts, lotus seeds 8-12 parts, fructus alpiniae oxyphyllae 4-8 parts, lophatherum gracile 4-8 parts.
2. a kind of Chinese medicine composition for improving the health care of sleep according to claim 1, it is characterised in that the Chinese medicine composition
In parts by weight, it is made up of following bulk drug：
31 parts of spina date seed, 31 parts of oyster, 16 parts of lily, 10 parts of lotus seeds, 6 parts of fructus alpiniae oxyphyllae, 6 parts of lophatherum gracile.
3. the preparation method of a kind of Chinese medicine composition for improving the health care of sleep according to claim 1-2 any one, its
It is characterised by, the method includes：
Step one：Spina date seed, oyster, lily, lotus seeds, fructus alpiniae oxyphyllae and lophatherum gracile are cleaned, is mixed, obtain mixture；
Step 2：The mixture that step one is obtained is extracted twice at 90-95 DEG C, each 2.5h, is then filtered with 300 mesh,
Obtain extract solution；
Step 3：Step 2 is obtained into extract solution to be concentrated under reduced pressure at 55-65 DEG C, by concentrate drying and screening, Chinese medicine group is obtained
Compound.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710234703.4A CN106924628A (en) | 2017-04-12 | 2017-04-12 | For Chinese medicine composition for improving the health care of sleep and preparation method thereof |
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| CN201710234703.4A CN106924628A (en) | 2017-04-12 | 2017-04-12 | For Chinese medicine composition for improving the health care of sleep and preparation method thereof |
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| CN106924628A true CN106924628A (en) | 2017-07-07 |
Family
ID=59425053
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109463589A (en) * | 2018-12-28 | 2019-03-15 | 凯瑞欧（天津）生物技术有限公司 | A kind of semen ziziphi spinosae formula beverage and preparation method thereof improving sleep quality |
| CN113331415A (en) * | 2021-06-02 | 2021-09-03 | 膳行天下(吉林)科技发展有限公司 | Medicated diet for people with sleep disorder |
| CN114271491A (en) * | 2021-12-15 | 2022-04-05 | 重庆市中药研究院 | Medicinal and edible composition for improving insomnia as well as preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106361964A (en) * | 2016-11-11 | 2017-02-01 | 南方医科大学 | Traditional Chinese medicinal composition for improving sleep quality as well as preparation method and application of traditional Chinese medicinal composition |
-
2017
- 2017-04-12 CN CN201710234703.4A patent/CN106924628A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106361964A (en) * | 2016-11-11 | 2017-02-01 | 南方医科大学 | Traditional Chinese medicinal composition for improving sleep quality as well as preparation method and application of traditional Chinese medicinal composition |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109463589A (en) * | 2018-12-28 | 2019-03-15 | 凯瑞欧（天津）生物技术有限公司 | A kind of semen ziziphi spinosae formula beverage and preparation method thereof improving sleep quality |
| CN113331415A (en) * | 2021-06-02 | 2021-09-03 | 膳行天下(吉林)科技发展有限公司 | Medicated diet for people with sleep disorder |
| CN114271491A (en) * | 2021-12-15 | 2022-04-05 | 重庆市中药研究院 | Medicinal and edible composition for improving insomnia as well as preparation method and application thereof |
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| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170707 |
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| RJ01 | Rejection of invention patent application after publication |