CN106924426A - A kind of antipruritic effervescent tablet of radix rehmanniae recen ceases wind - Google Patents
A kind of antipruritic effervescent tablet of radix rehmanniae recen ceases wind Download PDFInfo
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Abstract
The invention discloses a kind of antipruritic effervescent tablet of radix rehmanniae recen ceases wind, radix rehmanniae recen traditional Chinese medicine powder is made using radix rehmanniae recen, DUANLONGMU, radix scrophulariae, Radix Angelicae Sinensis, the red sage root, blood puncture vine, the taste Chinese medicine of honey-fried licorice root 7, add the raw materials such as borneol and NaHCO3, it is subject to auxiliary material again to be engaged, is made the antipruritic effervescent tablet of radix rehmanniae recen ceases wind of good water solubility；The present invention is that have the antipruritic effect of enriching the blood to restore normal menstruation, ceases wind and the borneol to have a swelling and pain relieving using radix rehmanniae recen traditional Chinese medicine powder, and heat-clearing dissipates poison dissipates the Chinese medicinal ingredients of fire removing toxic substances；The property of medicine is reasonably combined, can complement each other, promote drug effect；Particularly there is extraordinary therapeutic effect to pruritus scroti and vulval pruritus.
Description
Technical field
The present invention relates to the technical field of effervescent tablet, espespecially a kind of antipruritic effervescent tablet of radix rehmanniae recen ceases wind.
Background technology
Cutaneous pruritus refers to that skin is damaged without originality, only itch and a kind of skin disease of the secondary lesion caused by itch.This disease is apt to occur in the elderly and adult, is more common in winter.According to clinical manifestation, two kinds of general cutaneous pruritus and limitation cutaneous pruritus can be divided to.The former can all itch on the whole body, and position is indefinite, rises one after another, and is often paroxysmal, is attached most importance to night.Patient scratches incessantly because itching, and skin often has scratch, scab, pigmentation etc.；The latter's itch is limited only to a certain position, is common in anus, vulva, head, leg, metacarpus etc..Traditional Chinese medicine belongs to the categories such as pruritus due to wind pathogen, pruritus.
Radix rehmanniae recen is the root tuber of scrophulariaceae rehmannia glutinosa plant.Also known as ground marrow（《This warp》）, Proterozoic（《Herbal justice》）, dry Radix Rehmanniae（《Chinese medicinal herbal》）.Former plant glutinous rehmannia also known as：Benzyl（《It is elegant》）, glutinous rehmannia（《Do not record》）, autumn elaeagnus root leaf and fruit（《Amplification on Materia Medica》）, grandmother's milk（《Herbal for Relief of Famines》）, dog milk（《The Illustrated Book on Plants》）, mountain cigarette, mountain Chinese cabbage, wine pot flower, sweet wine, honey jar.In spindle or cylindrical strip, 8~24cm long.Outer thin skin, the pale red yellow in surface, vertical wrinkle, bud scar, grow crosswise hole skin and the irregular scar for having bending.Beaded is made in meat, easily broken, section skin zone yellowish white, it is seen that Chinese red oil drop, woody part yellow-white, middle contracting of often hanging, and conduit is arranged radially.Gas is micro-, the micro- sweet, slight bitter of taste.Radix rehmanniae recen：It is in the fast shape of irregular group or Long Circle, centre expands, two sections slightly thin, 6~12cm, 3~6cm of diameter long, what is had relatively thin, strip are slightly flat and bend more.Surface is dark brown or taupe, pole shrinkage, has irregular lateral flexure line.Body weight, matter is softer and tough, is not easily broken, and section is dark brown or corvinus, glossy, tool viscosity；With nourishing Yin and clearing heat, effect that cool blood is enriched blood.（Fresh rehmannia root：Clearing heat and cooling blood, fluid dryness.）
At present, although in the market has the products such as sophora flower pharmacy to occur, but also has no report using sophora flower madder traditional Chinese medicine powder making effervescent tablet, if sophora flower traditional Chinese medicine powder is produced into the effervescent tablet of convenient use by deep processing, can't hurt stomach and liver etc.；Can improve plus the economic worth of sophora flower can reach the purpose of medicinal health again, will be a good method killed two birds with one stone.
The content of the invention
A kind of antipruritic effervescent tablet of radix rehmanniae recen ceases wind of the present invention, radix rehmanniae recen traditional Chinese medicine powder is made using radix rehmanniae recen, DUANLONGMU, radix scrophulariae, Radix Angelicae Sinensis, the red sage root, blood puncture vine, the taste Chinese medicine of honey-fried licorice root 7, add the raw materials such as borneol and NaHCO3, it is subject to auxiliary material again to be engaged, the antipruritic effervescent tablet of radix rehmanniae recen ceases wind of good water solubility is made, the antipruritic purpose of quick ceases wind is realized.
To achieve these goals, technical solution of the invention is：A kind of main material component of the antipruritic effervescent tablet of radix rehmanniae recen ceases wind：Radix rehmanniae recen traditional Chinese medicine powder 49%~51%, NaH2CO3 40%~42%, borneol 5%~7%.
Auxiliary material component：The mL/ g dispensings of ethanol solution 0.12, Macrogol 6000 2%~4%.
Preparation process：
(1) extract:Radix rehmanniae recen, DUANLONGMU, radix scrophulariae, Radix Angelicae Sinensis, the red sage root, blood puncture vine, the removal of impurities of honey-fried licorice root difference, cleaning, drying, flour mill milling are obtained into radix rehmanniae recen traditional Chinese medicine powder；
(2) pelletize:Graininess is mixed into using the 70 % ethanol solutions containing 10 % polyvinylpyrrolidones (PVP) and radix rehmanniae recen traditional Chinese medicine powder, borneol, NaHCO3, with 20 and 30 mesh sieve whole grains, particle is in forced air drying at 50 DEG C to water content ＜ 3% between taking two sieves；
(3) compressing tablet:Take above-mentioned dry particle and Macrogol 6000
It is well mixed, enter tabletting machine.
The property of medicine of the various components of the present invention and effect：
Described radix rehmanniae recen：With heat-clearing, enriching yin of promoting the production of body fluid, blood-nourishing；Cure mainly：Fever due to yin deficiency is controlled, is quenched one's thirst, spitted blood, bleeding from five sense organs or subcutaneous tissue, metrorrhagia, irregular menstruation, fetal irritability, effect of the symptom such as impairment of yin constipation；
Described DUANLONGMU：With enhancing astringent or styptic treatment for spontaneous sweating, myogenic the effect of convergence, it is used for night sweat spontaneous perspiration, passes out semen, under band uterine bleeding, leukorrhea, protracted dysentery and diarrhea, the open sore part such as does not hold back at the effect of symptom；
Described radix scrophulariae：With clearing heat and cooling blood, purging intense heat and detonicating, enriching yin；Cure mainly：Effect of the symptoms such as warm heresy is joined the army, the pericardium that caves in, febrile virulent maculae, consumption of YIN caused by febrile disease, the deep red polydipsia of tongue, Tianjin hinder constipation, hectic fever due to yin labor is coughed, hot eyes, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus；
Described Radix Angelicae Sinensis：With benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation；For the deficiency of blood, sallow complexion, dizziness palpitaition, the deficiency of blood or have the stagnant irregular menstruation of the stasis of blood, Amenorrhea, dysmenorrhoea concurrently;The pain such as deficient cold type stomachache, coronary disease and angina pectoris, arthralgia pain due to rheumatism, traumatic injury card, dry constipation of intestines, effect of chronic cough asthma；
The described red sage root：With promoting blood circulation, nourishing blood and tranquilization, effect of cool blood detumescence；Hemostasis head, chest, the side of body, abdomen pain are cured mainly, is gathered, irregular menstruation, dysmenorrhoea Amenorrhea, postpartum stasis of blood, joint pain beats the stasis of blood swell, and warm disease is vexed, palpitation due to deficiency of blood, sore swollen toxin, effect of the symptom such as red rash mange；
Described blood puncture vine：With flat liver solution strongly fragrant, promoting blood circulation by removing wind, improving eyesight is antipruritic.For dizziness of having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, effect of rubella itch symptom；
Described honey-fried licorice root：With with middle emergency, moistening lung, removing toxic substances, coordinating the drug actions of a prescription.It is usually used in weakness of the spleen and the stomach, lassitude hypodynamia, severe palpilation, intermittent pulse can solve effect of monkshood toxication shape；
Described radix rehmanniae recen traditional Chinese medicine powder is that, by the removal of impurities of the 7 taste Chinese medicines such as 30 grams of radix rehmanniae recen, 15 grams of DUANLONGMU, 9 grams of radix scrophulariae, 9 grams of Radix Angelicae Sinensis, 9 grams of the red sage root, 9 grams of blood puncture vine, 6 grams of honey-fried licorice root difference, cleaning, drying, flour mill milling obtains radix rehmanniae recen traditional Chinese medicine powder after mixing；With the antipruritic effect of enriching the blood to restore normal menstruation, ceases wind；
Described borneol has logical all keys, dissipates stagnated fire, goes screen improving eyesight, and swelling and pain relieving, heat-clearing dissipates poison dissipates fire removing toxic substances.Control mammary gland caking, apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm fan, deafness with qi stagnation, larynx numbness, aphtha, tympanitis, carbuncle swells, hemorrhoid, mesh also screen film, effect of pinworm disease symptoms；
Described CO2 contents：NaHCO3
7.5mg/mL amount of water；
Used as adhesive, this solution usage is about 0.12 mL/g dispensings to 75% ethanol solution of the selection of described adhesive containing 10 %PVP.
Described selection has lubricity good, and resistance to bond is good, and the Macrogol 6000 of good water solubility is mixed before compressing tablet as the lubricant of effervescent tablet with particle, and addition is 2%~3%.
Described effervescent tablet monolithic agent weighs about 3. 52g, and after being dissolved in 200mL warm water, CO2 is sufficient, with being easy to the characteristics of transport, long shelf-life, making simple, easy to use；And good water solubility, i.e., punching i.e. wash, it is evident in efficacy, have no toxic side effect, it is cheap.
The antipruritic effervescent tablet of radix rehmanniae recen ceases wind of the present invention, if with the scorching patient of pruitus, effervescent tablet monolithic is dissolved in after 200mL warm water once a day, is washed every time 10 minutes, 51 courses for the treatment of, with a course for the treatment of it is obvious it is sterilized, moisturize, it is antipruritic；The present invention is that using radix rehmanniae recen traditional Chinese medicine powder there is the antipruritic effect of enriching the blood to restore normal menstruation, ceases wind and borneol to have a swelling and pain relieving, and heat-clearing dissipates poison dissipates the Chinese medicinal ingredients of fire removing toxic substances；The property of medicine is reasonably combined, can complement each other, promote drug effect；Particularly there is extraordinary therapeutic effect to pruritus scroti and vulval pruritus.
Specific embodiment
Embodiment 1
（1）Main material component：Radix rehmanniae recen traditional Chinese medicine powder 49%,
NaH2CO3 42%, borneol 7%；
Auxiliary material：The mL/g dispensings of ethanol solution 0.12, Macrogol 6000 2%.
（2）Technique preparation process：
1）Extraction:Radix rehmanniae recen, DUANLONGMU, radix scrophulariae, Radix Angelicae Sinensis, the red sage root, blood puncture vine, the removal of impurities of honey-fried licorice root difference, cleaning, drying, extraction are obtained into radix rehmanniae recen traditional Chinese medicine powder；
2）Granulation:Graininess is mixed into using 70% ethanol solution containing 10% polyvinylpyrrolidone (PVP) and radix rehmanniae recen traditional Chinese medicine powder, borneol, NaHCO3, with 20 and 30 mesh sieve whole grains, particle is in forced air drying at 50 DEG C to water content ＜ 3% between taking two sieves；
3）Compressing tablet:Take above-mentioned dry particle and Macrogol 6000
It is well mixed, enter tabletting machine.
Embodiment 2
（1）Main material component：Radix rehmanniae recen traditional Chinese medicine powder 50%,
NaH2CO3 41%, borneol 6%；
Auxiliary material：The mL/g dispensings of ethanol solution 0.12, Macrogol 6000 3%.
（2）Technique preparation process：
1) extract:Radix rehmanniae recen, DUANLONGMU, radix scrophulariae, Radix Angelicae Sinensis, the red sage root, blood puncture vine, the removal of impurities of honey-fried licorice root difference, cleaning, drying, extraction are obtained into radix rehmanniae recen traditional Chinese medicine powder；
2) pelletize:Graininess is mixed into using 70% ethanol solution containing 10% polyvinylpyrrolidone (PVP) and radix rehmanniae recen traditional Chinese medicine powder, borneol, NaHCO3, with 20 and 30 mesh sieve whole grains, particle is in forced air drying at 50 DEG C to water content ＜ 3% between taking two sieves；
3) compressing tablet:Take above-mentioned dry particle and Macrogol 6000
It is well mixed, enter tabletting machine.
Embodiment 3
（1）Main material component：Radix rehmanniae recen traditional Chinese medicine powder 51%,
NaH2CO3 40%, borneol 5%；
Auxiliary material：The mL/g dispensings of ethanol solution 0.12, Macrogol 6000 4%.
（2）Technique preparation process：
1) extract:Radix rehmanniae recen, DUANLONGMU, radix scrophulariae, Radix Angelicae Sinensis, the red sage root, blood puncture vine, the removal of impurities of honey-fried licorice root difference, cleaning, drying, extraction are obtained into radix rehmanniae recen traditional Chinese medicine powder；
2) pelletize:Graininess is mixed into using 70% ethanol solution containing 10% polyvinylpyrrolidone (PVP) and radix rehmanniae recen traditional Chinese medicine powder, borneol, NaHCO3, with 20 and 30 mesh sieve whole grains, particle is in forced air drying at 50 DEG C to water content ＜ 3% between taking two sieves；
3) compressing tablet:Take above-mentioned dry particle and Macrogol 6000
It is well mixed, enter tabletting machine.
The above; implementation method is only that the preferred embodiment of the present invention is described; not the scope of the present invention is defined; on the premise of the spirit for not departing from the technology of the present invention; various modifications and improvement that this area engineers and technicians make to technical scheme, all should fall into the protection domain of claims of the present invention determination.
Claims (2)
1. a kind of antipruritic effervescent tablet of radix rehmanniae recen ceases wind, it is characterized in that：The main material component of the antipruritic effervescent tablet of radix rehmanniae recen ceases wind：Radix rehmanniae recen traditional Chinese medicine powder 49%~51%, NaH2CO3
40%~42%, borneol 5%~7%；
Auxiliary material component：Ethanol solution 0.12
ML/ g dispensings, Macrogol 6000 2%~4%.
2. a kind of antipruritic effervescent tablet of radix rehmanniae recen ceases wind, it is characterized in that：Described radix rehmanniae recen traditional Chinese medicine powder is that, by the removal of impurities of the 7 taste Chinese medicines such as 30 grams of radix rehmanniae recen, 15 grams of DUANLONGMU, 9 grams of radix scrophulariae, 9 grams of Radix Angelicae Sinensis, 9 grams of the red sage root, 9 grams of blood puncture vine, 6 grams of honey-fried licorice root difference, cleaning, drying, flour mill milling obtains radix rehmanniae recen traditional Chinese medicine powder after mixing.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114129668A (en) * | 2021-11-29 | 2022-03-04 | 安徽省双辉生物科技有限公司 | Production method of radix rehmanniae decoction pieces capable of calming endogenous wind and relieving itching |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114129668A (en) * | 2021-11-29 | 2022-03-04 | 安徽省双辉生物科技有限公司 | Production method of radix rehmanniae decoction pieces capable of calming endogenous wind and relieving itching |
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| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170707 |