CN105902830A - Oncologic preparation for treating thyroid cancer and preparation method thereof - Google Patents
Oncologic preparation for treating thyroid cancer and preparation method thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses an oncologic preparation for treating thyroid cancer. The oncologic preparation is prepared from the following raw materials in parts by weight: 13-16 parts of celosia cristata, 13-17 parts of disporum cantoniense rhizome, 11-15 parts of dendrobium jenkinsii, 9-14 parts of swertia yunnanensis, 8-12 parts of semiaquilegia adoxoides, 11-16 parts of rose mallow root, 7-12 parts of berchemia lineata, 9-14 parts of Korean raspberry root, 9-13 parts of chamaenerion angustifolium rhizome, 7-12 parts of tangerine pith, 9-15 parts of acorus tatarinowii and 7-13 parts of ainsliaea latifolia. The oncologic preparation, which is prepared by reasonable and scientific compatibility of multiple Chinese medicinal herbs supplementing each other on effects, has the effects of activating blood circulation and stimulating meridians, reducing swelling and resolving mass, and invigorating spleen to remove phlem, is capable of effectively controling transfer and diffusion of thyroid cancer cells, and has a good effect of treating thyroid cancer and quick response.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of oncology for treating preparation and the system of thyroid cancer
Preparation Method.
Background technology
Thyroid cancer is modal thyroid malignancy, is derived from the malignant tumour of Thyroid follicular epithelial cell, absolutely
Major part thyroid cancer originates from follicular epithelial cells, accounts for the 1% of all cancers, popular at region nodular goiter
District, the incidence of disease of thyroid cancer the lowest differentiation thyroid cancer is the highest.By histological type can be divided into papillary carcinoma (60%),
Follicular adenocarcinoma (20%), but prognosis is preferable；Follicular adenocarcinoma tumor growth is very fast, belongs to moderate pernicious, and the operating of easy menses moves；Not
Differentiation cancer prognosis is very poor, mean survival time 3-6 month.In thyroid cancer the most common with papillary carcinoma.Age
Investigate incidence, annual less than 3/,100,000 in the male sex, and women really wants high 2-3 times, various types of thyroid cancer age distributions
The most different, papillary adenocarcinoma distribution is the widest, can betide less than 10 years old children and be more common in 20-100 to centenarian, filter blocking cancer
Year, cephaloma be more common in 40-80 year, undifferentiated carcinoma be more common in 40-90 year.
Thyroid cancer early clinical manifestation is inconspicuous, patient or household and doctor chance on neck thyroid gland have matter hard and
Rugged lump, many no conscious symptons, neck region lump is often asymmetry lump, and thyroid nodule lump can gradually increase
Greatly, up and down with swallowing, and tracheae can be invaded and fix, lump easily earlier generates pressure symptom, as with hoarseness, exhales
Inhale smooth, dysphagia, or the pressure symptom such as local tenderness, during jugular vein pressurized, may occur in which Ipsilateral venous engorgement and face water
, for one of the feature of thyroid cancer, such as Lung metastases and Bone tumour etc., even there is pathologic fracture in the sign such as swollen.Complication bag
Include hoarseness, dysphonia, dysphagia, have difficulty in breathing, cough and hemoptysis, whole body skeleton pain etc..
At present, the medicine for the treatment of thyroid cancer is a lot, publication No. CN 105521255 A(application number
201511004209.6) patent document discloses a kind of Chinese medicine preparation treating thyroid cancer, by following parts by weight
Medicine raw material is formulated: tendril-leaved fritillary bulb 12-15 part, centipede 2-3 part, selfheal 12-15 part, mock-strawberry 12-18 part, bittersweet 10-12 part, flea
Stop 8-12 part, radix ranunculi ternati 10-13 part, radix scrophulariae 12-18 part, subprostrate sophora 8-10 part, thunder godvine 14-17 part, first pearl 13-16 part, liter
Fiber crops 6-8 part, Radix Astragali 7-10 part, oyster 8-12 part, dragon's blood 6-12 part, Qiang roach 3-5 part, leech 2-3 part, Radix Angelicae Sinensis 10-13 part.Announce
Number CN 105327205 A(application number 201510872293.7) patent document disclose a kind of Chinese medicine treating thyroid cancer
Preparation, including the raw material of following weight portion: Poria cocos 10-15 part, Radix Codonopsis 15-20 part, parasitic loranthus 8-12 part, mushroom 10-15 part, red
Beans 8-12 part, root bark of white mulberry 8-12 part, bark of eucommia 10-15 part, akebi 10-15 part, dalbergia wood 8-12 part, bighead atractylodes rhizome 10-15 part, fiveleaf akebia fruit
10-15 part, Rhizoma Arisaematis (processed) 10-15 part, pawpaw 8-12 part, hairyvein agrimony 10-15 part, coix seed 8-12 part, garden burnet 8-12 part, Cynanchum glaucescens
10-15 part, Chinese lobelia 10-15 part, folium cycas 8-12 part, Herba Hedyotidis Diffusae 15-20 part, indigo naturalis 10-15 part, Chinese cassia tree 8-12 part,
Subprostrate sophora 15-20 part, polygala root 10-15 part, rhizoma alismatis 8-12 part, honeysuckle 15-20 part, pseudo-ginseng 8-12 part, peach kernel 8-12 part, centipede
8-12 part, caulis trachelospermi 10-15 part.Publication No. CN 103948576 A(application number 201410199769.0) patent document open
A kind of pharmaceutical composition treating thyroid cancer and application thereof, described pharmaceutical composition prepared by active component and auxiliary material and
Becoming, described active component includes parahydroxyacet-ophenone or derivatives thereof.
The medicine for the treatment of thyroid cancer is many at present is that primary and secondary effect is big with Western medicine, the easy impariment of the liver.More serious employing operation or
Chemotherapy, patient is painful big, deep to actual bodily harm.
Summary of the invention
For the deficiencies in the prior art, an object of the present invention is to provide a kind of oncology for treating thyroid cancer
Preparation, is formed by the reasonable scientific compatibility of Chinese herbal medicines, and drug effect complements each other, and having invigorates blood circulation stimulates the menstrual flow, dispersing swelling and dissipating binds, strengthening the spleen and reducing phlegm
Effect, effectively control transfer and the diffusion of thyroid carcinoma cell, treat thyroid cancer good effect, instant effect.The present invention's is another
One purpose is just to provide the preparation method of above-mentioned preparation.
The above-mentioned purpose of the present invention is achieved through the following technical solutions:
Oncology, for treating the preparation of thyroid cancer, is taken off and is stated the raw material of weight proportion and be prepared from: cockscomb 13-16 part；
Canton fairybells root and rhizome 13-17 part；Jenkine Dendrobium 11-15 part；Redflower gentian herb 9-14 part；Radix semiaquilegiae 8-12 part；Rose Mallow Root 11-16 part；Berchemia lineata
7-12 part；Korean raspberry root 9-14 part；Red chopsticks 9-13 part；Tangerine pith 7-12 part；Grass-leaved sweetflag 9-15 part；Broadleaf ainsliaea herb 7-13 part.
Oncology is for treating the preparation of thyroid cancer, and preferred scheme is, take off state weight proportion raw material preparation and
Become: cockscomb 14-15 part；Canton fairybells root and rhizome 14-16 part；Jenkine Dendrobium 12-14 part；Redflower gentian herb 11-13 part；Radix semiaquilegiae 9-11 part；Ground
Peach blossom 13-15 part；Berchemia lineata 9-11 part；Korean raspberry root 11-13 part；Red chopsticks 10-12 part；Tangerine pith 9-11 part；Grass-leaved sweetflag 11-13
Part；Broadleaf ainsliaea herb 9-11 part.
Oncology is for treating the preparation of thyroid cancer, and scheme more preferably is, takes off the raw material system stating weight proportion
For forming: cockscomb 14.5 parts；Canton fairybells root and rhizome 15 parts；Jenkine Dendrobium 13 parts；Redflower gentian herb 12 parts；Radix semiaquilegiae 10 parts；Rose Mallow Root 14 parts；
Berchemia lineata 10 parts；Korean raspberry root 12 parts；Red chopsticks 11 parts；Tangerine pith 10 parts；Grass-leaved sweetflag 12 parts；Broadleaf ainsliaea herb 10 parts.
Present invention also offers and above-mentioned oncology is used for treating the preparation of thyroid cancer makes pharmaceutically acceptable glue
The preparation method of capsule, decoction, pill, tablet and oral liquid.
Described oncology is for treating the preparation method of the preparation capsule of thyroid cancer, and step is as follows:
(1) being placed in container by radix semiaquilegiae, add the salt solution of 1.8%, soak 2-4 days, drain, moderate heat stir-fries 30-40 minute, dries in the air
Dry in the air, pulverize, cross 100-140 mesh sieve；
(2) being smashed to pieces by cockscomb, add the ethanol of 25%-35%, be heated to 33-36 DEG C, insulation is placed 6-8 hour, filters, and removes
Ethanol, obtains extract；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root are placed in non iron container, add yellow rice wine (the preferably use of yellow rice wine of 45-49
Amount is canton fairybells root and rhizome, berchemia lineata for canton fairybells root and rhizome, berchemia lineata and 3-5 times of korean raspberry root gross mass, the more preferably consumption of yellow rice wine and falls
4 times of gross mass of taking root), vexed profit dipping 4-6 hour；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, adding water, (the preferably consumption of water is red chopsticks, grass-leaved sweetflag and 8-12 times of broadleaf ainsliaea herb quality, more preferably
The consumption of water is 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality) soak 25-35 minute, decoct 40-50 minute, filter,
Liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 30-40 minute, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, being concentrated into relative density is 1.22-1.28
The thick paste of (38 DEG C), adds step (1) products therefrom, dry, pulverize, and crosses 120-160 mesh sieve, by the specification of 0.4-0.6g/ grain
Make capsule.
Above-mentioned oncology is for treating the preparation method of the preparation capsule of thyroid cancer, the consumption of step (1) preferably brine
For 8-10 times of radix semiaquilegiae quality, the more preferably consumption of salt solution is 9 times of radix semiaquilegiae quality.
Instructions of taking: each 2, every day 2 times, 6 days courses for the treatment of.
Described oncology is for treating the preparation method of the preparation decoction of thyroid cancer, and step is as follows:
(1) radix semiaquilegiae is placed in container, add 1.8% salt solution (consumption of preferably brine is 8-10 times of radix semiaquilegiae quality,
The more preferably consumption of salt solution is 9 times of radix semiaquilegiae quality), soak 2-4 days, drain, moderate heat stir-fries 30-40 minute, dries in the air, powder
Broken, cross 100-140 mesh sieve；
(2) being smashed to pieces by cockscomb, add the ethanol of 25%-35%, be heated to 33-36 DEG C, insulation is placed 6-8 hour, filters, and removes
Ethanol, obtains extract；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root being placed in non iron container, add the yellow rice wine of 45-49, dipping 4-6 is little for vexed profit
Time；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, adding water, (the preferably consumption of water is red chopsticks, grass-leaved sweetflag and 8-12 times of broadleaf ainsliaea herb quality, more preferably
The consumption of water is 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality) soak 25-35 minute, decoct 40-50 minute, filter,
Liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 30-40 minute, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 are mixed, add step (2) gained extract, be concentrated into the 1/2 of original volume, add step
Suddenly (1) products therefrom, stirs 8-10 minute, sterile packaged.
Above-mentioned oncology is used for treating the preparation method of the preparation decoction of thyroid cancer, the consumption of step (3) preferably yellow rice wine
It is canton fairybells root and rhizome, berchemia lineata and life of falling for canton fairybells root and rhizome, berchemia lineata and 3-5 times of korean raspberry root gross mass, the more preferably consumption of yellow rice wine
4 times of root gross mass.
Instructions of taking: 30-50ml every time, with the warm water delivery service of about 35 DEG C, every day 2-3 time, 5 days courses for the treatment of.
Described oncology is for treating the preparation method of the preparation pill of thyroid cancer, and step is as follows:
(1) radix semiaquilegiae is placed in container, add 1.8% salt solution (consumption of preferably brine is 8-10 times of radix semiaquilegiae quality,
The more preferably consumption of salt solution is 9 times of radix semiaquilegiae quality), soak 2-4 days, drain, moderate heat stir-fries 30-40 minute, dries in the air, powder
Broken, cross 100-140 mesh sieve；
(2) being smashed to pieces by cockscomb, add the ethanol of 25%-35%, be heated to 33-36 DEG C, insulation is placed 6-8 hour, filters, and removes
Ethanol, obtains extract；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root are placed in non iron container, add yellow rice wine (the preferably use of yellow rice wine of 45-49
Amount is canton fairybells root and rhizome, berchemia lineata for canton fairybells root and rhizome, berchemia lineata and 3-5 times of korean raspberry root gross mass, the more preferably consumption of yellow rice wine and falls
4 times of gross mass of taking root), vexed profit dipping 4-6 hour；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, adding water, (the preferably consumption of water is red chopsticks, grass-leaved sweetflag and 8-12 times of broadleaf ainsliaea herb quality, more preferably
The consumption of water is 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality) soak 25-35 minute, decoct 40-50 minute, filter,
Liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 30-40 minute, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, being concentrated into relative density is 1.22-1.28
The thick paste of (38 DEG C), adds step (1) products therefrom, mixes, and dries, and pulverizes, obtains medicinal powder；
(7) by honey (preferably the consumption of honey be the consumption of the 30%-40% of medicinal powder quality, more preferably honey be medicinal powder quality
35%) be placed in pot, slow fire is tempered to thick, add step (6) gained medicinal powder, fully mix into ointment thoroughly, make pill
(being preferably made the pill of a diameter of 3mm-5mm, more preferably make the pill of a diameter of 4mm).
Instructions of taking: 10-15 ball, every day 2 times, 6 days courses for the treatment of every time.
Described oncology is for treating the preparation method of the formulation tablet of thyroid cancer, and step is as follows:
(1) radix semiaquilegiae is placed in container, add 1.8% salt solution (consumption of preferably brine is 8-10 times of radix semiaquilegiae quality,
The more preferably consumption of salt solution is 9 times of radix semiaquilegiae quality), soak 2-4 days, drain, moderate heat stir-fries 30-40 minute, dries in the air, powder
Broken, cross 100-140 mesh sieve；
(2) being smashed to pieces by cockscomb, add the ethanol of 25%-35%, be heated to 33-36 DEG C, insulation is placed 6-8 hour, filters, and removes
Ethanol, obtains extract；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root are placed in non iron container, add yellow rice wine (the preferably use of yellow rice wine of 45-49
Amount is canton fairybells root and rhizome, berchemia lineata for canton fairybells root and rhizome, berchemia lineata and 3-5 times of korean raspberry root gross mass, the more preferably consumption of yellow rice wine and falls
4 times of gross mass of taking root), vexed profit dipping 4-6 hour；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, adding water, (the preferably consumption of water is red chopsticks, grass-leaved sweetflag and 8-12 times of broadleaf ainsliaea herb quality, more preferably
The consumption of water is 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality) soak 25-35 minute, decoct 40-50 minute, filter,
Liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 30-40 minute, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, being concentrated into relative density is 1.22-1.28
The thick paste of (38 DEG C), adds step (1) products therefrom, mixes, be placed in granulator and make single-size, is dried, compacting
Slabbing, sugar coating.
Instructions of taking: 2-3 sheet, every day 2 times, 6 days courses for the treatment of every time.
Described oncology is for treating the preparation method of the preparation oral liquid of thyroid cancer, and step is as follows:
(1) radix semiaquilegiae is placed in container, add 1.8% salt solution (consumption of preferably brine is 8-10 times of radix semiaquilegiae quality,
The more preferably consumption of salt solution is 9 times of radix semiaquilegiae quality), soak 2-4 days, drain, moderate heat stir-fries 30-40 minute, dries in the air, powder
Broken, cross 100-140 mesh sieve；
(2) being smashed to pieces by cockscomb, add the ethanol of 25%-35%, be heated to 33-36 DEG C, insulation is placed 6-8 hour, filters, and removes
Ethanol, obtains extract；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root are placed in non iron container, add yellow rice wine (the preferably use of yellow rice wine of 45-49
Amount is canton fairybells root and rhizome, berchemia lineata for canton fairybells root and rhizome, berchemia lineata and 3-5 times of korean raspberry root gross mass, the more preferably consumption of yellow rice wine and falls
4 times of gross mass of taking root), vexed profit dipping 4-6 hour；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, adding water, (the preferably consumption of water is red chopsticks, grass-leaved sweetflag and 8-12 times of broadleaf ainsliaea herb quality, more preferably
The consumption of water is 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality) soak 25-35 minute, decoct 40-50 minute, filter,
Liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 30-40 minute, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, concentration relative density is 1.02-1.05
(28 DEG C), add step (1) products therefrom, stir 8-10 minute, add Sodium Benzoate and flavouring, mixing, and sterilization 10-20 divides
Clock, carries out sterile packaged with the dosage of every 6ml.
Instructions of taking: 1-2 props up every time, every day 2 times, 6 days courses for the treatment of.
The technical advantage of the present invention is mainly reflected in:
1, oncology of the present invention is formed by the reasonable scientific compatibility of Chinese herbal medicines for the preparation treating thyroid cancer, and drug effect is mutually auxiliary
Coordinating, having invigorates blood circulation stimulates the menstrual flow, dispersing swelling and dissipating binds, effect of strengthening the spleen and reducing phlegm, effectively controls transfer and the diffusion of thyroid carcinoma cell, controls
Treat thyroid cancer good effect, instant effect.
2, oncology of the present invention effectively suppresses tumor growth for the preparation treating thyroid cancer, shifts, spreads, and shortens
The band knurl time of patient, reach to kill the purpose of tumor suppression cell；It is effectively improved immunocompetence and the organismic internal environment of body simultaneously
Ability of regulation and control.
3, oncology of the present invention can reduce lump in a short time for the preparation treating thyroid cancer, palliates the agonizing sufferings, stable
The state of an illness, extends life cycle, reaches clinical cure, and its late result and long-term survival rate are respectively provided with obvious effect.
4, oncology of the present invention is pure Chinese medicinal preparation for treating the preparation of thyroid cancer, and medicinal material is easy to get, low cost, and
Mild in medicine property and, have no side effect, it is to avoid stomach is damaged, have no side effect.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
Embodiment 1 oncology, for treating the preparation of thyroid cancer, is taken off and is stated the raw material of weight proportion and be prepared from (every part
Take 79g): cockscomb 13 parts；Canton fairybells root and rhizome 13 parts；Jenkine Dendrobium 11 parts；Redflower gentian herb 9 parts；Radix semiaquilegiae 8 parts；Rose Mallow Root 11 parts；Iron bag
Gold 7 parts；Korean raspberry root 9 parts；Red chopsticks 9 parts；Tangerine pith 7 parts；Grass-leaved sweetflag 9 parts；Broadleaf ainsliaea herb 7 parts.
Above-mentioned oncology is for treating the preparation method of the preparation capsule of thyroid cancer, and step is as follows:
(1) radix semiaquilegiae is placed in container, adds the salt solution 9 times of radix semiaquilegiae quality (consumption be) of 1.8%, soak 3 days, drain,
Moderate heat stir-fries 35 minutes, dries in the air, and pulverizes, and crosses 120 mesh sieves；
(2) being smashed to pieces by cockscomb, add the ethanol of 25%-35%, be heated to 34 DEG C, insulation is placed 7 hours, filters, and removes ethanol,
Obtain extract；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root being placed in non iron container, (consumption is canton fairybells root and rhizome, iron to the yellow rice wine of addition 47
Covered with gold leaf and 4 times of korean raspberry root gross mass), vexed profit dipping 5 hours；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, add water 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality (consumption be) soaks 30 minutes, decocts 45 points
Clock, filters, obtains liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 35 minutes, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, being concentrated into relative density is 1.26(38
DEG C) thick paste, add step (1) products therefrom, dry, pulverize, cross 140 mesh sieves, make capsule by the specification of 0.5g/ grain.
Instructions of taking: each 2, every day 2 times, 6 days courses for the treatment of.
Embodiment 2 oncology, for treating the preparation of thyroid cancer, is taken off and is stated the raw material of weight proportion and be prepared from (every part
34g): cockscomb 16 parts；Canton fairybells root and rhizome 17 parts；Jenkine Dendrobium 15 parts；Redflower gentian herb 14 parts；Radix semiaquilegiae 12 parts；Rose Mallow Root 16 parts；Iron bag
Gold 12 parts；Korean raspberry root 14 parts；Red chopsticks 13 parts；Tangerine pith 12 parts；Grass-leaved sweetflag 15 parts；Broadleaf ainsliaea herb 13 parts.
Above-mentioned oncology is for treating the preparation method of the preparation decoction of thyroid cancer, and step is as follows:
(1) radix semiaquilegiae is placed in container, adds the salt solution 9 times of radix semiaquilegiae quality (consumption be) of 1.8%, soaks 2-4 days, drip
Dry, moderate heat stir-fries 35 minutes, dries in the air, and pulverizes, and crosses 120 mesh sieves；
(2) being smashed to pieces by cockscomb, add the ethanol of 30%, be heated to 34 DEG C, insulation is placed 7 hours, filters, and removes ethanol, must carry
Take liquid；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root being placed in non iron container, (consumption is canton fairybells root and rhizome, iron to the yellow rice wine of addition 47
Covered with gold leaf and 4 times of korean raspberry root gross mass), vexed profit dipping 5 hours；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, add water 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality (consumption be) soaks 30 minutes, decocts 45 points
Clock, filters, obtains liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 35 minutes, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 are mixed, add step (2) gained extract, be concentrated into the 1/2 of original volume, add step
Suddenly (1) products therefrom, stirs 9 minutes, sterile packaged.
Instructions of taking: 40ml, every day 2 times, 6 days courses for the treatment of every time.
Model case one poplar XX, female, 49 years old, people from Tai'an, Shandong Province.Originally Mrs Yang realizes that neck swells and ache, and has hard thing,
When swallowing thing, pain becomes apparent from, and then goes to clinic, thinks it is tonsillotome inflammation, takes 1 week nothing of antiphlogistic and alleviates.And go out
Existing lump increases, and physique declines, all-overish phenomenon, then goes examination in hospital, CT display thyroid gland portion tumour.Expectant treatment
After one wheat harvesting period, symptom is not obviously improved, and lump is gradually increased.
Take oncology of the present invention after 2 courses for the treatment of of preparation (embodiment 2) treating thyroid cancer, thyroid nodule matter
Ground deliquescing, swallows smooth and easy, and when swallowing, pain substantially alleviates, and health becomes light.Continuing to take 2 courses for the treatment of, physique strengthens, after
Neck is subsided a swelling, and throat discomfort of neck area is substantially alleviated, and CT display thyroid gland region tumors knurl body reduces, and other position does not finds new life
Tumour.Following up a case by regular visits to 2 years have no recurrence, health is good.
Embodiment 3 oncology, for treating the preparation of thyroid cancer, is taken off and is stated the raw material of weight proportion and be prepared from (every part
Take 57g): cockscomb 14 parts；Canton fairybells root and rhizome 14 parts；Jenkine Dendrobium 12 parts；Redflower gentian herb 11 parts；Radix semiaquilegiae 9 parts；Rose Mallow Root 13 parts；Iron
9 parts covered with gold leaf；Korean raspberry root 11 parts；Red chopsticks 10 parts；Tangerine pith 9 parts；Grass-leaved sweetflag 11 parts；Broadleaf ainsliaea herb 9 parts.
Above-mentioned oncology is for treating the preparation method of the preparation pill of thyroid cancer, and step is as follows:
(1) radix semiaquilegiae is placed in container, adds the salt solution 9 times of radix semiaquilegiae quality (consumption be) of 1.8%, soak 3 days, drain,
Moderate heat stir-fries 35 minutes, dries in the air, and pulverizes, and crosses 120 mesh sieves；
(2) being smashed to pieces by cockscomb, add the ethanol of 30%, be heated to 34 DEG C, insulation is placed 7 hours, filters, and removes ethanol, must carry
Take liquid；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root being placed in non iron container, (consumption is canton fairybells root and rhizome, iron to the yellow rice wine of addition 47
Covered with gold leaf and 4 times of korean raspberry root gross mass), vexed profit dipping 5 hours；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, add water 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality (consumption be) soaks 30 minutes, decocts 45 points
Clock, filters, obtains liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 35 minutes, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, being concentrated into relative density is 1.26(38
DEG C) thick paste, add step (1) products therefrom, mix, dry, pulverize, obtain medicinal powder；
(7) being placed in pot by honey (consumption is the 35% of medicinal powder quality), slow fire is tempered to thick, adds step (6) gained medicine
Powder, fully mixes into ointment thoroughly, makes the pill of a diameter of 4mm.
Instructions of taking: each 10 balls, every day 2 times, 6 days courses for the treatment of.
Embodiment 4 oncology, for treating the preparation of thyroid cancer, is taken off and is stated the raw material of weight proportion and be prepared from (every part
Take 35g): cockscomb 15 parts；Canton fairybells root and rhizome 16 parts；Jenkine Dendrobium 14 parts；Redflower gentian herb 13 parts；Radix semiaquilegiae 11 parts；Rose Mallow Root 15 parts；Iron
11 parts covered with gold leaf；Korean raspberry root 13 parts；Red chopsticks 12 parts；Tangerine pith 11 parts；Grass-leaved sweetflag 13 parts；Broadleaf ainsliaea herb 11 parts.
Above-mentioned oncology is for treating the preparation method of the formulation tablet of thyroid cancer, and step is as follows:
(1) radix semiaquilegiae is placed in container, adds the salt solution 9 times of radix semiaquilegiae quality (consumption be) of 1.8%, soak 3 days, drain,
Moderate heat stir-fries 35 minutes, dries in the air, and pulverizes, and crosses 120 mesh sieves；
(2) being smashed to pieces by cockscomb, add the ethanol of 30%, be heated to 34 DEG C, insulation is placed 7 hours, filters, and removes ethanol, must carry
Take liquid；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root being placed in non iron container, (consumption is canton fairybells root and rhizome, iron to the yellow rice wine of addition 47
Covered with gold leaf and 4 times of korean raspberry root gross mass), vexed profit dipping 5 hours；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, add water 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality (consumption be) soaks 30 minutes, decocts 45 points
Clock, filters, obtains liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 35 minutes, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, being concentrated into relative density is 1.26(38
DEG C) thick paste, add step (1) products therefrom, mix, be placed in granulator and make single-size, be dried, tabletted
Shape, sugar coating.
Instructions of taking: 2-3 sheet, every day 2 times, 6 days courses for the treatment of every time.
Model case two Xue XX, man, 29 years old, people from Ganzhou City of Jiangxi Province.Lump, lump surface is had without throat under obvious inducement
Uneven, sound is more hoarse, and up and down along with swallowing, and has pain when swallowing, and then removes examination in hospital, and CT shows first
Shape gland portion tumour.Hospitalization, continuous transfusion 1 month, without remarkable result, lump is gradually increased, and physique declines, weak all over.
Taking oncology of the present invention after 2 courses for the treatment of of preparation (embodiment 4) treating thyroid cancer, lump quality becomes
Soft, the state of mind is clearly better.After continuing to take 2 courses for the treatment of, lump is subsided a swelling, and throat discomfort of neck area is substantially alleviated, and CT shows first
Shape gland region tumors diameter reduces, and does not finds nascent tumor, and physique strengthens.Following up a case by regular visits to 1 year have no recurrence, health is good.
Embodiment 5 oncology, for treating the preparation of thyroid cancer, is taken off and is stated the primary raw material of weight proportion and be prepared from
(every part takes 40g): cockscomb 14.5 parts；Canton fairybells root and rhizome 15 parts；Jenkine Dendrobium 13 parts；Redflower gentian herb 12 parts；Radix semiaquilegiae 10 parts；Rose Mallow Root
14 parts；Berchemia lineata 10 parts；Korean raspberry root 12 parts；Red chopsticks 11 parts；Tangerine pith 10 parts；Grass-leaved sweetflag 12 parts；Broadleaf ainsliaea herb 10 parts.
Above-mentioned oncology is for treating the preparation method of the preparation oral liquid of thyroid cancer, and step is as follows:
(1) radix semiaquilegiae is placed in container, adds the salt solution 9 times of radix semiaquilegiae quality (consumption be) of 1.8%, soak 3 days, drain,
Moderate heat stir-fries 35 minutes, dries in the air, and pulverizes, and crosses 120 mesh sieves；
(2) being smashed to pieces by cockscomb, add the ethanol of 30%, be heated to 34 DEG C, insulation is placed 7 hours, filters, and removes ethanol, must carry
Take liquid；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root being placed in non iron container, (consumption is canton fairybells root and rhizome, iron to the yellow rice wine of addition 47
Covered with gold leaf and 4 times of korean raspberry root gross mass), vexed profit dipping 7 hours；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, add water 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality (consumption be) soaks 30 minutes, decocts 45 points
Clock, filters, obtains liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 35 minutes, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, concentration relative density is 1.02-1.05
(28 DEG C), add step (1) products therefrom, stir 9 minutes, add Sodium Benzoate and flavouring, mixing, are sterilized 15 minutes, with
The dosage of every 6ml carries out sterile packaged.
Instructions of taking: 1-2 props up every time, every day 2 times, 6 days courses for the treatment of.
Used by the present invention, the pharmacology of main Chinese medicine material is as follows:
Cockscomb: taste is sweet, cool in nature.Return liver, kidney channel.For the inflorescence of amaranthaceous plant cockscomb, containing Kaempferitrin, amaranth glucoside, pine camphor
And a large amount of potassium nitrate.There is cool blood, effect of hemostasis.Blood under anal fistula, red white diarrhea, to spit blood, hemoptysis, blood drenches, and women is collapsed
In, leukorrhea with reddish discharge.
Canton fairybells root and rhizome: bitter, pungent, cool in nature.Root and rhizome for liliaceous plant cantonese fairy bells.There is wines used as antirheumatic, relax the muscles and stimulate the blood circulation,
Effect of heat-clearing expelling phlegm and arresting coughing.For rheumatism bi Zheng, joint lumbocrural pain, traumatic injury, fracture, consumptive disease, osteopyrexia and fever, tuberculosis
Spitting of blood, cough with lung heat, burn and scald.
Jenkine Dendrobium: taste is sweet, light, cool in nature.Attach to the lung and stomach meridians.Herb for the poly-stem of noble dendrobium of orchid.Have and moisten the lung and relieve the cough, grow
Effect of cloudy nourishing the stomach.For cough with lung heat, pulmonary tuberculosis, asthma, dysentery, stomatitis, stomachache, infant malnutrition.
Redflower gentian herb: bitter, cold in nature.The thoughts of returning home, lung, stomach, large intestine channel.Root and herb for gentianaceae plant red gentian.
There is clearing heat and promoting diuresis, effect of removing pattogenic heat from the blood and toxic material from the body.Coughing for lung heat and breathe heavily, consumptive disease is coughed phlegm blood, jaundice, and dysentery is had blood in stool, difficult urination, produces
Cotton-padded mattress heat, child convulsion, infantile malnutrition due to digestive disturbances or intestinalparasites, sore swollen toxin, burn and scald, snake bite.
Radix semiaquilegiae: bitter, micro-hardship, micro-pungent, cold in nature.Return liver, spleen, bladder warp.Block root for ranunculaceae plant semiaquilegia adoxoides.Have
Clearing heat and detoxicating, dispersing swelling and dissipating binds, effect of promoting diuresis for stranguria.Shying for children's's heat, epilepsy, carbuncle swells, and furunculosis, acute mastitis, scrofula, skin is itched
Sore, red eye, swell pain, pharyngalgia, snake bite and insect sting, heat pouring, sand drenches.
Rose Mallow Root: taste is sweet, pungent, cool in nature.Return lung, the spleen channel.For Malvaceae plant Rose Mallow Root or the root of thick leaf Rose Mallow Root or complete
Grass.There is expelling wind and removing dampness, the kind that disappears of invigorating blood circulation, effect of heat reliving and toxin-eliminating.For catching a cold, arthralgia due to wind-dampness, dysentery, have loose bowels, stranguria, band
Under, irregular menstruation, treating swelling and pain by traumatic injury, larynx numbness, acute mastitis, sore furuncle, venomous snake bite.
Berchemia lineata: bitter, micro-puckery, property is put down.The thoughts of returning home, lung channel.Covered with gold leaf and the stem rattan of littleleaf supplejackherba for Rhamnaceae plant iron
Or root.There is subdhing swelling and detoxicating, hemostatic analgesia, the effect dispelled rheumatism.For ulcer serious case of furuncle, cough spitting of blood, hemorrhage of digestive tract, fall
Play damage, scald, treating rheumatic ostealgia, acute toothache.
Korean raspberry root: taste is sour, salty, property is put down.Root for rosaceous plant rubus coreanus.Have and invigorate blood circulation, effect of hemostasis.For labor
Wound is spitted blood, nosebleed epistaxis, irregular menstruation, traumatic injury, fracture, infertility, irregular menstruation, nosebleed epistaxis.
Red chopsticks: taste is pungent, bitter, property is put down.Root-like stock or herb for Oenotheraceae willow herb platymiscium willow herb.Containing positive 29
Alkane, ceryl alcohol, Β-sitosterol, ursolic acid, sitosterol-Β d-glycoside, sitosterol palmitate ester, sitosterol decylate, paddy steroid
Alcohol caprylate, sitosterol caproate, the existing acid esters of sitosterol.There is clearing damp and promoting diuresis, dissipate-swelling of regulating the flow of vital energy, effect of promoting blood circulation for regulating menstruation.For
Oedema, has loose bowels, dyspepsia turgor, irregular menstruation, alactation, scrotum enlargement, and sore rash is itched bitterly.
Tangerine pith: taste is sweet, bitter, property is put down.Return liver, the spleen channel.Pericarp internal layer grain for rutaceae orange and variety thereof.
There is dredging collateral, regulate the flow of vital energy, the effect reduced phlegm.For blockage of meridian-QI,stagnation of QI in meridian, chronic cough pectoralgia, blood-stained sputum, get sick from drinking too much wine thirsty.
Grass-leaved sweetflag: taste is pungent, bitter, slightly warm in nature.The thoughts of returning home, liver, the spleen channel.Rhizome for acorus gramineus araceae plant.Having
Phlegm is had one's ideas straightened out, dampness elimination promoting the circulation of qi, profit of dispeling the wind numbness, effect of swelling and pain relieving.For pyreticosis coma, coma due to blocking of the respiratory system, forgetful, tinnitus, deaf, gastral cavity abdomen
Distending pain, dysentery with vomiting, arthralgia due to wind-dampness, traumatic injury, ulcer mange.
Broadleaf ainsliaea herb: taste hardship pungent, micro-, warm in nature.Herb for composite family Ainsliaea platymiscium width fringe Ainsliaea.Have dispel the wind scattered
Cold, effect of activating blood circulation and reducing swelling.For anemofrigid cold, headache, pain in the back, intestines fire, dysentery, fall dozen stasis of blood and swell, traumatism and bleeding, tympanitis,
Mastitis.
Test example in order to verify oncology of the present invention for treating the curative effect of the preparation (embodiment 5) of thyroid cancer, in
Do contrast test in May ,-2013 in August, 2011:
General data: screen 260 example thyroid cancer patients, wherein male patient 94 people, female patient 166 people.It is randomly divided into
Experimental group and two groups of control group (wherein experimental group 160 people, control group 100 people), comment in sex, age, the course of disease, the state of an illness for two groups
Aspect of grading compares that there was no significant difference (P ＞ 0.05), has comparativity.
Usage and dosage: experimental group takes oncology of the present invention for treating the preparation oral liquid of thyroid cancer, each 2,
Every day 2 times, 6 days courses for the treatment of.Control group uses other medicine (such as XIAOAIPING PIAN, cantharides capsule etc.), and wherein, the cancer that disappears is put down
Sheet, oral, a 8-10 sheet, 3 times on the one.Cantharides capsule, oral, one time 3,2 times on the one.
Criterion of therapeutical effect: cure: physique strengthens, throat discomfort of neck area is substantially alleviated, and CT shows thyroid gland region tumors knurl body
Reducing, other position does not finds nascent tumor.Effective: throat discomfort of neck area is alleviated, CT display thyroid gland portion tumour knurl body has no
Increasing, other position does not finds nascent tumor.Invalid: all diseases are without improving, and thyroid gland region tumors knurl body increases, or other positions
Find nascent tumor.
Use the control group of other drug and take oncology of the present invention for treating the experimental group of the preparation of thyroid cancer
Comparison of therapeutic, result is as shown in table 1:
Table 1
As it can be seen from table 1 take oncology of the present invention to be up to 68.13% for the cure rate treating the preparation of thyroid cancer, have
Efficiency is up to 95.63%；And take the cure rate only 31% of other drug, efficient also only have 74%, and inefficiency is up to 26%.
So the effect of the preparation that oncology of the present invention is for treating thyroid cancer is substantially better than the effect of other drug, treat thyroid gland
Cancer curative effect is more significantly, and clinic is promoted.
It should be pointed out that, the detailed description of the invention more representational example that is the present invention, it is clear that the skill of the present invention
Art scheme is not limited to above-described embodiment, it is also possible to have many variations.Those of ordinary skill in the art, the most public with present invention institute
That open or according to file written description obtains undoubtedly, is all considered as this patent scope of the claimed.
Claims (10)
1. oncology is for treating the preparation of thyroid cancer, it is characterized in that, takes off and states the raw material of weight proportion and be prepared from: cockscomb
Flower 13-16 part；Canton fairybells root and rhizome 13-17 part；Jenkine Dendrobium 11-15 part；Redflower gentian herb 9-14 part；Radix semiaquilegiae 8-12 part；Rose Mallow Root 11-16
Part；Berchemia lineata 7-12 part；Korean raspberry root 9-14 part；Red chopsticks 9-13 part；Tangerine pith 7-12 part；Grass-leaved sweetflag 9-15 part；Broadleaf ainsliaea herb 7-13
Part.
Preparation the most according to claim 1, is characterized in that, takes off and states the raw material of weight proportion and be prepared from: cockscomb 14-
15 parts；Canton fairybells root and rhizome 14-16 part；Jenkine Dendrobium 12-14 part；Redflower gentian herb 11-13 part；Radix semiaquilegiae 9-11 part；Rose Mallow Root 13-15 part；
Berchemia lineata 9-11 part；Korean raspberry root 11-13 part；Red chopsticks 10-12 part；Tangerine pith 9-11 part；Grass-leaved sweetflag 11-13 part；Broadleaf ainsliaea herb 9-11
Part.
Preparation the most according to claim 1, is characterized in that, takes off and states the raw material of weight proportion and be prepared from: cockscomb
14.5 parts；Canton fairybells root and rhizome 15 parts；Jenkine Dendrobium 13 parts；Redflower gentian herb 12 parts；Radix semiaquilegiae 10 parts；Rose Mallow Root 14 parts；Berchemia lineata 10 parts；Fall
Take root 12 parts；Red chopsticks 11 parts；Tangerine pith 10 parts；Grass-leaved sweetflag 12 parts；Broadleaf ainsliaea herb 10 parts.
4. according to the preparation method of the arbitrary described preparation capsule of claim 1-3, it is characterized in that, step is as follows:
(1) being placed in container by radix semiaquilegiae, add the salt solution of 1.8%, soak 2-4 days, drain, moderate heat stir-fries 30-40 minute, dries in the air
Dry in the air, pulverize, cross 100-140 mesh sieve；
(2) being smashed to pieces by cockscomb, add the ethanol of 25%-35%, be heated to 33-36 DEG C, insulation is placed 6-8 hour, filters, and removes
Ethanol, obtains extract；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root are placed in non iron container, add yellow rice wine (the preferably use of yellow rice wine of 45-49
Amount is canton fairybells root and rhizome, berchemia lineata for canton fairybells root and rhizome, berchemia lineata and 3-5 times of korean raspberry root gross mass, the more preferably consumption of yellow rice wine and falls
4 times of gross mass of taking root), vexed profit dipping 4-6 hour；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, adding water, (the preferably consumption of water is red chopsticks, grass-leaved sweetflag and 8-12 times of broadleaf ainsliaea herb quality, more preferably
The consumption of water is 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality) soak 25-35 minute, decoct 40-50 minute, filter,
Liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 30-40 minute, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, being concentrated into relative density is 1.22-1.28
Thick paste, add step (1) products therefrom, dry, pulverize, cross 120-160 mesh sieve, make glue by the specification of 0.4-0.6g/ grain
Capsule.
The preparation method of preparation capsule the most according to claim 4, is characterized in that: the consumption of step (1) preferably brine is
The consumption of 8-10 times of radix semiaquilegiae quality, more preferably salt solution is 9 times of radix semiaquilegiae quality.
6. according to the preparation method of the arbitrary described preparation decoction of claim 1-3, it is characterized in that, step is as follows:
(1) radix semiaquilegiae is placed in container, add 1.8% salt solution (consumption of preferably brine is 8-10 times of radix semiaquilegiae quality,
The more preferably consumption of salt solution is 9 times of radix semiaquilegiae quality), soak 2-4 days, drain, moderate heat stir-fries 30-40 minute, dries in the air, powder
Broken, cross 100-140 mesh sieve；
(2) being smashed to pieces by cockscomb, add the ethanol of 25%-35%, be heated to 33-36 DEG C, insulation is placed 6-8 hour, filters, and removes
Ethanol, obtains extract；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root being placed in non iron container, add the yellow rice wine of 45-49, dipping 4-6 is little for vexed profit
Time；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, adding water, (the preferably consumption of water is red chopsticks, grass-leaved sweetflag and 8-12 times of broadleaf ainsliaea herb quality, more preferably
The consumption of water is 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality) soak 25-35 minute, decoct 40-50 minute, filter,
Liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 30-40 minute, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 are mixed, add step (2) gained extract, be concentrated into the 1/2 of original volume, add step
Suddenly (1) products therefrom, stirs 8-10 minute, sterile packaged.
The preparation method of preparation decoction the most according to claim 6, is characterized in that: the consumption of step (3) preferably yellow rice wine is
Canton fairybells root and rhizome, berchemia lineata and 3-5 times of korean raspberry root gross mass, the more preferably consumption of yellow rice wine are canton fairybells root and rhizome, berchemia lineata and korean raspberry root
4 times of gross mass.
8. according to the preparation method of the arbitrary described preparation pill of claim 1-3, it is characterized in that, step is as follows:
(1) radix semiaquilegiae is placed in container, add 1.8% salt solution (consumption of preferably brine is 8-10 times of radix semiaquilegiae quality,
The more preferably consumption of salt solution is 9 times of radix semiaquilegiae quality), soak 2-4 days, drain, moderate heat stir-fries 30-40 minute, dries in the air, powder
Broken, cross 100-140 mesh sieve；
(2) being smashed to pieces by cockscomb, add the ethanol of 25%-35%, be heated to 33-36 DEG C, insulation is placed 6-8 hour, filters, and removes
Ethanol, obtains extract；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root are placed in non iron container, add yellow rice wine (the preferably use of yellow rice wine of 45-49
Amount is canton fairybells root and rhizome, berchemia lineata for canton fairybells root and rhizome, berchemia lineata and 3-5 times of korean raspberry root gross mass, the more preferably consumption of yellow rice wine and falls
4 times of gross mass of taking root), vexed profit dipping 4-6 hour；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, adding water, (the preferably consumption of water is red chopsticks, grass-leaved sweetflag and 8-12 times of broadleaf ainsliaea herb quality, more preferably
The consumption of water is 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality) soak 25-35 minute, decoct 40-50 minute, filter,
Liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 30-40 minute, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, being concentrated into relative density is 1.22-1.28
Thick paste, add step (1) products therefrom, mix, dry, pulverize, obtain medicinal powder；
(7) by honey (preferably the consumption of honey be the consumption of the 30%-40% of medicinal powder quality, more preferably honey be medicinal powder quality
35%) be placed in pot, slow fire is tempered to thick, add step (6) gained medicinal powder, fully mix into ointment thoroughly, make pill
(being preferably made the pill of a diameter of 3mm-5mm, more preferably make the pill of a diameter of 4mm).
9. according to the preparation method of the arbitrary described formulation tablet of claim 1-3, it is characterized in that, step is as follows:
(1) radix semiaquilegiae is placed in container, add 1.8% salt solution (consumption of preferably brine is 8-10 times of radix semiaquilegiae quality,
The more preferably consumption of salt solution is 9 times of radix semiaquilegiae quality), soak 2-4 days, drain, moderate heat stir-fries 30-40 minute, dries in the air, powder
Broken, cross 100-140 mesh sieve；
(2) being smashed to pieces by cockscomb, add the ethanol of 25%-35%, be heated to 33-36 DEG C, insulation is placed 6-8 hour, filters, and removes
Ethanol, obtains extract；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root are placed in non iron container, add yellow rice wine (the preferably use of yellow rice wine of 45-49
Amount is canton fairybells root and rhizome, berchemia lineata for canton fairybells root and rhizome, berchemia lineata and 3-5 times of korean raspberry root gross mass, the more preferably consumption of yellow rice wine and falls
4 times of gross mass of taking root), vexed profit dipping 4-6 hour；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, adding water, (the preferably consumption of water is red chopsticks, grass-leaved sweetflag and 8-12 times of broadleaf ainsliaea herb quality, more preferably
The consumption of water is 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality) soak 25-35 minute, decoct 40-50 minute, filter,
Liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 30-40 minute, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, being concentrated into relative density is 1.22-1.28
Thick paste, add step (1) products therefrom, mix, be placed in granulator and make single-size, be dried, be compressed into tablet form,
Sugar coating.
10. according to the preparation method of the arbitrary described preparation oral liquid of claim 1-3, it is characterized in that, step is as follows:
(1) radix semiaquilegiae is placed in container, add 1.8% salt solution (consumption of preferably brine is 8-10 times of radix semiaquilegiae quality,
The more preferably consumption of salt solution is 9 times of radix semiaquilegiae quality), soak 2-4 days, drain, moderate heat stir-fries 30-40 minute, dries in the air, powder
Broken, cross 100-140 mesh sieve；
(2) being smashed to pieces by cockscomb, add the ethanol of 25%-35%, be heated to 33-36 DEG C, insulation is placed 6-8 hour, filters, and removes
Ethanol, obtains extract；
(3) canton fairybells root and rhizome, berchemia lineata and korean raspberry root are placed in non iron container, add yellow rice wine (the preferably use of yellow rice wine of 45-49
Amount is canton fairybells root and rhizome, berchemia lineata for canton fairybells root and rhizome, berchemia lineata and 3-5 times of korean raspberry root gross mass, the more preferably consumption of yellow rice wine and falls
4 times of gross mass of taking root), vexed profit dipping 4-6 hour；
(4) Jenkine Dendrobium, redflower gentian herb, Rose Mallow Root and tangerine pith are placed in gauze bag, sealing, be placed in marmite, add red chopsticks,
Grass-leaved sweetflag and broadleaf ainsliaea herb, adding water, (the preferably consumption of water is red chopsticks, grass-leaved sweetflag and 8-12 times of broadleaf ainsliaea herb quality, more preferably
The consumption of water is 10 times of red chopsticks, grass-leaved sweetflag and broadleaf ainsliaea herb quality) soak 25-35 minute, decoct 40-50 minute, filter,
Liquid 1 and the dregs of a decoction；
(5) step (4) the gained dregs of a decoction are replaced in marmite, add step (3) gains, boiling twice, decoct every time
Boil 30-40 minute, filter, merging filtrate, obtain liquid 2；
(6) liquid 1 and liquid 2 being mixed, add step (2) gained extract, concentration relative density is 1.02-1.05,
Add step (1) products therefrom, stir 8-10 minute, add Sodium Benzoate and flavouring, mixing, be sterilized 10-20 minute, with often
The dosage propping up 6ml carries out sterile packaged.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610334051.7A CN105902830A (en) | 2016-05-19 | 2016-05-19 | Oncologic preparation for treating thyroid cancer and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201610334051.7A CN105902830A (en) | 2016-05-19 | 2016-05-19 | Oncologic preparation for treating thyroid cancer and preparation method thereof |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1265901A (en) * | 2000-01-26 | 2000-09-13 | 徐忠廷 | Traditional Chinese medicinal pill for anti-cancer |
| CN1745641A (en) * | 2005-09-26 | 2006-03-15 | 全英滨 | Vegetative for tified anticancer flour |
-
2016
- 2016-05-19 CN CN201610334051.7A patent/CN105902830A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1265901A (en) * | 2000-01-26 | 2000-09-13 | 徐忠廷 | Traditional Chinese medicinal pill for anti-cancer |
| CN1745641A (en) * | 2005-09-26 | 2006-03-15 | 全英滨 | Vegetative for tified anticancer flour |
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