CN106902210A

CN106902210A - It is a kind of to treat medicine of functional uterine bleeding and preparation method thereof

Info

Publication number: CN106902210A
Application number: CN201710175965.8A
Authority: CN
Inventors: 陆燕
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-03-23
Filing date: 2017-03-23
Publication date: 2017-06-30

Abstract

Medicine of functional uterine bleeding and preparation method thereof is treated the invention discloses a kind of, it is mainly by radix bupleuri, keel, oyster, radix rehmanniae recen, the fruit of glossy privet, the bighead atractylodes rhizome, scouring rush, eclipta, cuttlebone, rheum officinale, rhizome of cyrtomium, hairyvein agrimony, pseudo-ginseng, moutan bark, lilac daphne, thizoma curculiginis, Gorgon fruit, deer horn glue, fushen, teasel root, the bark of eucommia, Radix Codonopsis, cape jasmine, palm, yncaria stem with hooks is prepared from according to a certain weight ratio, medicine of the present invention has clearing heat and detoxicating, cooling blood and hemostasis, hemostasis stasis, detumescence ding-tong, the function of tonifying middle-Jiao and Qi, for treating functional uterine bleeding instant effect, good effect, do not recur.

Description

It is a kind of to treat medicine of functional uterine bleeding and preparation method thereof

Technical field

Medicine of functional uterine bleeding and preparation method thereof is treated the present invention relates to a kind of, belongs to the field of Chinese medicines.

Background technology

Functional uterine bleeding is a kind of common gynecological disease, refers to abnormal uterine hemorrhage, is not found after indagation There are whole body and reproductive organs organic disease, but caused by neuroendocrine system functional disturbance.Show as the menstrual cycle It is irregular, through amount it is excessive, menostaxis or irregular bleeding.Because western medicine side effect is big, therefore people are to effectively treatment There is great demand in the Chinese medicine of functional uterine bleeding, up to now, it has not been found that on relevant report of the invention Road.

The content of the invention

The present inventor have found and effectively control treatment functions finally according to the checking repeatedly of research and the clinical test of theory of traditional Chinese medical science The medicine of property uterine hemorrhage, so as to complete the present invention.

It is an object of the invention to provide a kind of Chinese medicine composition of effective treatment functional uterine bleeding.

Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.

Medicine of the present invention be selection radix bupleuri, keel, oyster, radix rehmanniae recen, the fruit of glossy privet, the bighead atractylodes rhizome, scouring rush, eclipta, cuttlebone, Rheum officinale, rhizome of cyrtomium, hairyvein agrimony, pseudo-ginseng, moutan bark, lilac daphne, thizoma curculiginis, Gorgon fruit, deer horn glue, fushen, teasel root, the bark of eucommia, Radix Codonopsis, cape jasmine, Palm, yncaria stem with hooks, garden burnet, the fruit of Cherokee rose, the fleece-flower root, thizoma curculiginis are combined preparation, and these drug regimens are caused into each efficacy of drugs Produce synergy such that it is able to effectively treat functional uterine bleeding.It is cool wherein from radix bupleuri because its is bitter in taste, enter Liver, gallbladder channel, have with inducing diaphoresis, and soothing the liver, the function of rising Yang controls fevers and chills alternate, and fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria Disease, lower sharp prolapse of the anus, irregular menstruation, metroptosis.From keel because its property sweet-puckery flavor, puts down, the heart, liver, kidney, large intestine are included into Through, there is tranquillizing the mind by relieving convulsion, the function of arrest sweating controlling nocturnal emission with astringent drugs, Zhi Jing Epilepsy is demented, and palpitation is forgetful, insomnia and dreamful sleep, spontaneous sweating.It is from oyster Because its nature and flavor is salty and bitter, cool, enter liver and kidney channel, hold back the moon, checking exuberance of yang, hidroschesis, the function of puckery essence controls frightened Epilepsy, and dizziness, spontaneous perspiration is stolen Sweat, seminal emission, stranguria with turbid discharge, uterine bleeding, under band, scrofula, goiter and tumor.From radix rehmanniae recen because its nature and flavor is sweet, tremble with fear, the thoughts of returning home, liver and kidney channel have Clearing heat and cooling blood, yin-nourishing, the function of promoting the production of body fluid controls pyreticosis polydipsia, and yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, Heat Diabetes is spitted blood, and bleeding from five sense organs or subcutaneous tissue sends out spot Dermexanthesis.From the fruit of glossy privet because its nature and flavor bitter sweet, puts down, enter liver and kidney channel, there is filling liver kidney, the function of strong waist and knee is controlled in the deficiency of Yin Heat, dizzy, mesh flower tinnitus, soreness and weakness of waist and knees, poliosis.From the bighead atractylodes rhizome because its nature and flavor bitter sweet, temperature, enter spleen, stomach, there is benefit Spleen, beneficial stomach, eliminating dampness, and in function, control deficient QI of the spleen and stomach, do not feel like eating, the few gas of burnout, empty swollen, diarrhea, phlegm and retained fluid, oedema is yellow Subcutaneous ulcer, arthritis with fixed pain caused by dampness, difficult urination is dizzy, and spontaneous perspiration, nausea is uneasy.From scouring rush because its nature and flavor sweetness and bitterness, puts down, enter lung, liver, gallbladder channel, There is wind-dispelling heat-dissipating, expelling pathogenic factors from muscles and skin moves back the function of screen, control mesh life cloudiness, tearing against wind, discharging fresh blood stool, bloody flux, prolapse of the anus, malaria is had sore throat, Carbuncle swells.From eclipta because its nature and flavor picric acid, cool, enter liver and kidney channel, there is cool blood, stop blooding, kidney tonifying, the cloudy function of benefit is controlled and told Blood, hemoptysis, bleeding from five sense organs or subcutaneous tissue, hematuria is had blood in stool, bloody flux, knife wound bleeding, poliosis, diphtheria, stranguria with turbid discharge, it is stagnant under, private parts is wet to itch.From sea Because its nature and flavor is salty, tepor enters liver and kidney channel to the egg capsule of a mantis, there is a dehumidifying, relieving haperacidity, hemostasis, the function of sore, and treat for stomachache acid regurgitation, tell, Nosebleed, spitting blood, have blood in stool, uterine bleeding under band, amenorrhea due to blood depletion, Fu Tong Disorder lumps in the abdomen, empty malaria rush down dysentery, erosion of vulva rotten sore.From rheum officinale because its property It is bitter, cold, enter stomach, large intestine, liver footpath, there is the poison that purges heat, break stagnant, the function of row hemostasis controls real heat constipation, and delirious speech is gone mad, dyspepsia Feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menopause Bi , lumps in the chest and abdomen, when the hot epidemic disease of row, sudden and violent swelling ophthalmalgia spits blood, bleeding from five sense organs or subcutaneous tissue, yang jaundice, water Swollen, stranguria with turbid discharge is urinated red, large carbuncle pyogenic infections, furunculosis, burn.It is cool from rhizome of cyrtomium because its is bitter in taste, enter liver, stomach, kill ascarid, Silk ribbon, pinworm, heat-clearing, removing toxic substances, cool blood, the function of hemostasis control anemopyretic cold, and damp and hot ecchymosis is spitted blood, bleeding from five sense organs or subcutaneous tissue, hematochezia, blood Dysentery, metrorrhagia, under band.From hairyvein agrimony because its nature and flavor toil, puts down, enter lung, liver, the spleen channel, there is hemostasis, the function of stomach invigorating is controlled Spitting of blood, is spitted blood, and hematuria is had blood in stool, and dysentery, uterine bleeding under band, internal lesion caused by overexertion takes off power, carbuncle swells, bruise, traumatic bleeding.It is from pseudo-ginseng Because its property sweet and slightly bitter taste, temperature, enter liver, stomach, large intestine channel have hemostasis, dissipate the stasis of blood, and detumescence, the function of analgesic therapy controls haematemesis, hemoptysis, nosebleed Blood, has blood in stool, bloody flux, uterine bleeding , Disorder lumps in the abdomen, postpartum anemic fainting, lochia not under, fall and flutter hemostasis, traumatism and bleeding, carbuncle swells pain.From tree peony Skin is cool because its nature and flavor is arduous, enters the heart, liver and kidney channel, there is heat-clearing, cool blood, and blood, and the function of dispersing blood stasis controls heat invading xuefen, hair Spot , Jing Epilepsy, tells, is defeated in battle, has blood in stool, and hectic fever due to yin labor heat, Amenorrhea , Disorder lumps in the abdomen, large carbuncle flutters damage.From lilac daphne because its nature and flavor is arduous, temperature, It is poisonous, enter lung, the spleen channel, relieve oedema or abdominal distension through diuresis or purgation, the function of phlegm is washed, the phlegm and retained fluid hypochondriac lump is controlled, breath with cough, oedema, hypochondriac pain, Xin Fu Disorder knot distending pains, food Poisoning, malaria is female, carbuncle swells.From thizoma curculiginis because its nature and flavor is pungent, temperature is poisonous, enters kidney, Liver Channel, there is warm kidney sun, the work(for strengthening the bone Can, control impotence cold sperm, aconuresis, uterine bleeding, trusted subordinate's crymodynia, cold arthralgia of loins and legs, ulcer, scrofula.From Gorgon fruit because its nature and flavor It is sweet puckery, put down, enter spleen, kidney channel, there is reinforcing the kidney and controlling noctural emission, tonifying spleen stopping leak controls seminal emission, stranguria with turbid discharge, under band, urinary incontinence, stool diarrhea.From Because its property sweet-salty, temperature enters liver and kidney channel to deer horn glue, enriches blood, and the function of strengthening the essence controls deficiency of kidney-QI, and consumptive disease is thin thin, waist Bitterly, cloudy subcutaneous ulcer, impotence in male, involuntary emission, uterus void is cold, uterine bleeding, under band.From fushen because its property slightly sweet flavor, puts down, enter The heart, the spleen channel, there is calming heart, calm the nerves, the function of Li Shui, control palpitation with fear of having a guilty conscience, forgetful, insomnia, shy Epilepsy, difficult urination.It is from teasel root Because its nature and flavor toil, tepor enters liver and kidney channel, there is a filling liver kidney, continuous muscles and bones adjust the function of blood vessels, control aching pain in waist and back, sufficient knee without Power, threatened abortion, uterine bleeding, under band, seminal emission, traumatic injury, metal-inflicted wound, anal fistula, ulcer sore swells.From the bark of eucommia because its nature and flavor is sweet micro- Pungent, temperature enters liver and kidney channel, there is filling liver kidney, and strengthening the bones and muscles, antiabortive function controls spinal column ache, foot and knee flaccidity, dribbling urination, under the moon Wet to itch, threatened abortion is intended to fall, hypertension.From Radix Codonopsis because its nature and flavor is sweet, put down, start with, meridian of Foot-TAI YIN qi leel, there is tonifying middle-Jiao and Qi, The function of promoting the production of body fluid, controls weakness of the spleen and the stomach, and qi-blood deficiency, body is tired powerless, and deficiency of food is thirsty, chronic diarrhea, prolapse of the anus.From cape jasmine because its It is bitter in taste, tremble with fear, enter the heart, liver, lung, stomach, there is heat-clearing, purging intense heat, the function of cool blood controls pyreticosis restlessness of asrhenia type and insomnia, and jaundice, gonorrhoea disappears Yearningly, hot eyes, pharyngalgia is spitted blood, and bleeding from five sense organs or subcutaneous tissue, bloody flux, hematuria, pathopyretic ulcer is sprained and swollen and ache.From palm because its is bitter in taste, puckery, Flat, return lung, liver, large intestine channel, the function of having controlling of bleeding with astringents control haematemesis, and bleeding from five sense organs or subcutaneous tissue is had blood in stool, metrostaxis.From yncaria stem with hooks because its Bitter in taste, cool, enter liver, the heart channel of Hang-Shaoyin have The flat liver of heat-clearing, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and control little Jing Epilepsy Chi Zong, adult's slight Hypertension, head Dizzy, dizzy, married woman's sub- Epilepsy.From garden burnet because its nature and flavor picric acid, trembles with fear, enter liver, large intestine channel have cooling blood and hemostasis, clearing heat and detoxicating Function, control haematemesis, bleeding from five sense organs or subcutaneous tissue, bloody flux, uterine bleeding, intestines wind, anal fistula, carbuncle swells, eczema, metal-inflicted wound, burn.From the fruit of Cherokee rose because its Nature and flavor are sour and astringent, put down, and have reinforcing the kidney and controlling nocturnal emission, and the function of reducing urination and antidiarrheal controls involuntary emission, the enuresis, frequent urination, insufficiency of the spleen rush down dysentery.It is first from what Because its nature and flavor bitter sweet is puckery, tepor enters liver and kidney channel to crow, there is tonifying liver, and kidney-nourishing, blood-nourishing, the function of wind-dispelling controls liver-kidney Yin deficiency, hair Must be early white, the deficiency of blood is dizzy, and waist and knee is weak, and muscles and bones is ached, and passes out semen, and collapses band, chronic malaria, protracted dysentery, chronic hepatitis, carbuncle swells, scrofula, intestines Wind, haemorrhoids.From thizoma curculiginis because its nature and flavor is pungent, temperature is poisonous, enters kidney, Liver Channel, there is warm kidney sun, and the function of strengthening the bone controls impotence Cold sperm, aconuresis, uterine bleeding, trusted subordinate's crymodynia, cold arthralgia of loins and legs, ulcer, scrofula.

Specific embodiment

The drug dose of instant component is also that inventor summarizes what is drawn by largely groping, and the consumption of each component is following heavy All there is preferable curative effect in the range of amount：

4-8 grams of radix bupleuri, 25-35 grams of keel, 25-35 grams of oyster, 25-35 grams of radix rehmanniae recen, 5-15 grams of the fruit of glossy privet, 5-15 grams of the bighead atractylodes rhizome, 5-15 grams of scouring rush, 5-15 grams of eclipta, 5-15 grams of cuttlebone, 5-15 grams of rheum officinale, 10-20 grams of rhizome of cyrtomium, 10-20 grams of hairyvein agrimony, three Seven 5-10 grams, 5-15 grams of moutan bark, 3-5 grams of lilac daphne, 10-20 grams of thizoma curculiginis, 5-15 grams of Gorgon fruit, 4-8 grams of deer horn glue, fushen 5-15 Gram, 5-15 grams of teasel root, 5-15 grams of the bark of eucommia, 15-25 grams of Radix Codonopsis, 5-15 grams of cape jasmine, 5-15 grams of palm, 10-14 grams of yncaria stem with hooks, garden burnet 5- 15 grams, 10-20 grams of the fruit of Cherokee rose, 10-20 grams of the fleece-flower root, 5-15 grams of thizoma curculiginis.

Preferably：

6 grams of radix bupleuri, 30 grams of keel, 30 grams of oyster, 30 grams of radix rehmanniae recen, 10 grams of the fruit of glossy privet, 10 grams of the bighead atractylodes rhizome, 10 grams of scouring rush, eclipta 10 grams, 10 grams of cuttlebone, 10 grams of rheum officinale, 15 grams of rhizome of cyrtomium, 15 grams of hairyvein agrimony, 5 grams of pseudo-ginseng, 10 grams of moutan bark, 5 grams of lilac daphne, thizoma curculiginis 15 grams, 10 grams of Gorgon fruit, 6 grams of deer horn glue, 10 grams of fushen, 10 grams of teasel root, 10 grams of the bark of eucommia, 20 grams of Radix Codonopsis, 10 grams of cape jasmine, palm 10 Gram, 12 grams of yncaria stem with hooks, 10 grams of garden burnet, 15 grams of the fruit of Cherokee rose, 15 grams of the fleece-flower root, 10 grams of thizoma curculiginis.

The preparation method of medicine of the present invention is as follows

First, get the raw materials ready

1st, radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulled out, section in time, dries immediately after running through；

2nd, keel：Outwash soil, smashes；

3rd, oyster：Clean, dry, pulverize use；

4th, radix rehmanniae recen：Crude drug is taken, impurity is removed, cleaned, slightly moistened, cut sheet, dried, weed out chip；

5th, the fruit of glossy privet：Impurity is picked, is cleaned, dried；

6th, the bighead atractylodes rhizome：Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried；

7th, scouring rush：Clean, slightly moisten, cut off root, segment is dried；

8th, eclipta：Net impurity is picked, undesirable root is removed, clean vexed, segment is dried；

9th, cuttlebone：Scrub clean, dry, pound into fritter；

10th, rheum officinale：Take rhubarb tablets to put in pot, it is in burnt brown to fry with high heat to outside, slightly sprays clear water, and taking-up is dried；

11st, rhizome of cyrtomium：Take net rhizome of cyrtomium piece to fry to coke black, spray clear water, cool；

12nd, hairyvein agrimony：Impurity undesirable root is removed, is cleaned, run through, cut off, dried；

13rd, pseudo-ginseng：Net impurity is picked, is smashed to pieces；

14th, moutan bark：Impurity is picked, core is removed, cleaned, run through, cut into slices, dried；

15th, lilac daphne：Net impurity is picked, soil is weeded out；

16th, thizoma curculiginis：Take net thizoma curculiginis to be mixed thoroughly with yellow rice wine, after running through, put micro- stir-fry in pot and, to dry, take out, dry, per 100 jin of thizoma curculiginis, use 10-20 jin of yellow rice wine；

17th, Gorgon fruit：To first be fried to cigarette in wheat bran heat release pot and risen, then net Gorgon fruit is poured into, stirred to slightly yellow, taken out, well sifted bran Skin, cools；

18th, deer horn glue：Crude drug is taken, impurity is removed, the used time smashs to pieces；

19th, fushen：Crude drug is taken, impurity is removed, cleaned, run through, be cut into foursquare sheet or block, dried in the shade；

20th, teasel root：Silt is cleaned, retained root head is removed, section is dried after running through, and weeds out bits；

21st, the bark of eucommia：Tertia is removed, is cleaned, run through, dice or strand are dried；

22nd, Radix Codonopsis：Reed, section or segment are run through after cleaning silt, is dried；

23rd, cape jasmine：Grey bits are weeded out, impurity is picked, sieving is pulverized or is cut off two ends；

24th, palm：Crude drug is taken, impurity is removed, cleaned, stripping and slicing, dried；

25th, yncaria stem with hooks：Old stalk, impurity are picked, is cleaned, dried；

26th, garden burnet：Impurity is picked, is washed, slightly soaked, run through, be cut into sheet, dried；

27th, the fruit of Cherokee rose：Impurity is picked, two valves are cut, is slightly soaked with water, pulled out, residual burr is removed after vexed profit, dig net hair, core, done It is dry；

28th, the fleece-flower root：Impurity is picked, is cleaned, pulled out with bubble to eighty per cant thoroughly, profit is uniform to inside and outside humidity, cuts into slices or the side of being cut into Block, dries；

29th, thizoma curculiginis：Take net thizoma curculiginis to be mixed thoroughly with yellow rice wine, after running through, put micro- stir-fry in pot and, to dry, take out, dry, per 100 jin of thizoma curculiginis, use 10-20 jin of yellow rice wine.

2nd, prepare

1st, by the radix bupleuri of the weight, keel, oyster, radix rehmanniae recen, the fruit of glossy privet, the bighead atractylodes rhizome, scouring rush, eclipta, cuttlebone, rheum officinale, Rhizome of cyrtomium, hairyvein agrimony, pseudo-ginseng, moutan bark, lilac daphne, thizoma curculiginis, Gorgon fruit, deer horn glue, fushen, teasel root, the bark of eucommia, Radix Codonopsis, cape jasmine, palm, Yncaria stem with hooks, garden burnet, the fruit of Cherokee rose, the fleece-flower root, thizoma curculiginis are put into decocting container, are added water 8 times and are measured, and after soaking 100 minutes, are fried by intense fire and are boiled Rise, then with being cooked by slow fire 20 minutes, filter to obtain first time decoction liquor, first time decoction liquor is poured into container；

2nd, the dregs of a decoction of filtering are added water 6 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；

3rd, will decoction liquor mixing and stirring twice, be divided into 4 doses and take.

Cuttlebone has dehumidifying in prescription, and relieving haperacidity is stopped blooding, and the function of sore is monarch drug in a prescription；Rhizome of cyrtomium has heat-clearing, removing toxic substances, cool blood, only The function of blood；Pseudo-ginseng has hemostasis, dissipates the stasis of blood, subsides a swelling, the function of analgesic therapy, and the two is ministerial drug, and three taste medicines play clearing heat and detoxicating jointly, cool Blood stops blooding, hemostasis stasis, the effect of detumescence ding-tong, and treatment functional uterine bleeding effect is comprehensive, and with cooling blood and hemostasis, styptic powder The stasis of blood, can be effected a permanent cure based on detumescence ding-tong, and deer horn glue is enriched blood, and the function of strengthening the essence is adjutant, and Radix Codonopsis has tonifying middle-Jiao and Qi, the function of promoting the production of body fluid To make medicine, all medicines are to take stopgap measures with being left.

Medicine of the present invention has clearing heat and detoxicating, cooling blood and hemostasis, and hemostasis stasis, detumescence ding-tong, the function of tonifying middle-Jiao and Qi is used for Treatment functional uterine bleeding, short treating period, instant effect, non-relapse after healing.

The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include this hair The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.

The animal toxicity test report of [test example 1] medicine of the present invention：

Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, and every group 15, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, takes medicine continuously 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic and side effect.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1st, physical data

Accept functional uterine bleeding out-patient totally 36 for medical treatment.

2nd, diagnostic criteria

Classical symptom is irregular uterine hemorrhage, and the confusion of the menstrual cycle, prolonged bleeding time is more through blood volume, or even measures greatly Blood is dripping more than.It is No-clay weak interbed type and the major class of ovulation type two generally by work(blood system according to whether ovulating, the former is the most common, 80~90% are accounted for, puberty and climacteric is occurred mainly in, the latter is more common in women at fertile age.

3rd, treatment method

From above-mentioned medicament, taken to patient, each take 1 dose, early daily, evening respectively takes 1 time, be within 7 days a course for the treatment of, continuous clothes With 4 courses for the treatment of.

4th, efficacy assessment standard

It is effective：Functional uterine bleeding symptom disappears, and recovers normal, recovery from illness；

Take a turn for the better：Functional uterine bleeding symptom is clearly better, and the menstrual cycle progressively recovers normal；

It is invalid：Improvement standard person is not reached.

5th, treatment results（See the table below）

In above-mentioned treatment, with drug therapy functional uterine bleeding of the present invention 36, as a result effective 28, obvious effective rate is 83.3%, take a turn for the better 4, improvement rate is 11.1%, and invalid 2, total effective rate is 94.4%.

Claims

1. a kind of medicine for treating functional uterine bleeding, it is characterised in that：It is by the bulk drug system in following weight range Into：

2. medicine according to claim 1, wherein the consumption of each bulk drug is：

3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：

（One）Get the raw materials ready

（1）Radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulled out, section in time, dries immediately after running through；

（2）Keel：Outwash soil, smashes；

（3）Oyster：Clean, dry, pulverize use；

（4）Radix rehmanniae recen：Crude drug is taken, impurity is removed, cleaned, slightly moistened, cut sheet, dried, weed out chip；

（5）The fruit of glossy privet：Impurity is picked, is cleaned, dried；

（6）The bighead atractylodes rhizome：Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried；

（7）Scouring rush：Clean, slightly moisten, cut off root, segment is dried；

（8）Eclipta：Net impurity is picked, undesirable root is removed, clean vexed, segment is dried；

（9）Cuttlebone：Scrub clean, dry, pound into fritter；

（10）Rheum officinale：Take rhubarb tablets to put in pot, it is in burnt brown to fry with high heat to outside, slightly sprays clear water, and taking-up is dried；

（11）Rhizome of cyrtomium：Take net rhizome of cyrtomium piece to fry to coke black, spray clear water, cool；

（12）Hairyvein agrimony：Impurity undesirable root is removed, is cleaned, run through, cut off, dried；

（13）Pseudo-ginseng：Net impurity is picked, is smashed to pieces；

（14）Moutan bark：Impurity is picked, core is removed, cleaned, run through, cut into slices, dried；

（15）Lilac daphne：Net impurity is picked, soil is weeded out；

（16）Thizoma curculiginis：Take net thizoma curculiginis to be mixed thoroughly with yellow rice wine, after running through, put micro- stir-fry in pot and, to dry, take out, dry, per 100 jin of thizoma curculiginis, With 10-20 jin of yellow rice wine；

（17）Gorgon fruit：To first be fried to cigarette in wheat bran heat release pot and risen, then net Gorgon fruit is poured into, stirred to slightly yellow, taken out, well sifted bran Skin, cools；

（18）Deer horn glue：Crude drug is taken, impurity is removed, the used time smashs to pieces；

（19）Fushen：Crude drug is taken, impurity is removed, cleaned, run through, be cut into foursquare sheet or block, dried in the shade；

（20）Teasel root：Silt is cleaned, retained root head is removed, section is dried after running through, and weeds out bits；

（21）The bark of eucommia：Tertia is removed, is cleaned, run through, dice or strand are dried；

（22）Radix Codonopsis：Reed, section or segment are run through after cleaning silt, is dried；

（23）Cape jasmine：Grey bits are weeded out, impurity is picked, sieving is pulverized or is cut off two ends；

（24）Palm：Crude drug is taken, impurity is removed, cleaned, stripping and slicing, dried；

（25）Yncaria stem with hooks：Old stalk, impurity are picked, is cleaned, dried；

（26）Garden burnet：Impurity is picked, is washed, slightly soaked, run through, be cut into sheet, dried；

（27）The fruit of Cherokee rose：Impurity is picked, two valves are cut, is slightly soaked with water, pulled out, residual burr is removed after vexed profit, dig net hair, core, Dry；

（28）The fleece-flower root：Impurity is picked, is cleaned, pulled out with bubble to eighty per cant thoroughly, profit is uniform to inside and outside humidity, cuts into slices or is cut into Square, dries；

（29）Thizoma curculiginis：Take net thizoma curculiginis to be mixed thoroughly with yellow rice wine, after running through, put micro- stir-fry in pot and, to dry, take out, dry, per 100 jin of thizoma curculiginis, With 10-20 jin of yellow rice wine；

（Two）Prepare

（1）By the radix bupleuri of the weight, keel, oyster, radix rehmanniae recen, the fruit of glossy privet, the bighead atractylodes rhizome, scouring rush, eclipta, cuttlebone, rheum officinale, Rhizome of cyrtomium, hairyvein agrimony, pseudo-ginseng, moutan bark, lilac daphne, thizoma curculiginis, Gorgon fruit, deer horn glue, fushen, teasel root, the bark of eucommia, Radix Codonopsis, cape jasmine, palm, Yncaria stem with hooks, garden burnet, the fruit of Cherokee rose, the fleece-flower root, thizoma curculiginis are put into decocting container, are added water 8 times and are measured, and after soaking 100 minutes, are fried by intense fire and are boiled Rise, then with being cooked by slow fire 20 minutes, filter to obtain first time decoction liquor, first time decoction liquor is poured into container；

（2）The dregs of a decoction of filtering are added water 6 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；

（3）Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 4 doses and is taken.