CN106890121A - A kind of multifunctional gargle and preparation method thereof - Google Patents

A kind of multifunctional gargle and preparation method thereof Download PDF

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Publication number
CN106890121A
CN106890121A CN201710122125.5A CN201710122125A CN106890121A CN 106890121 A CN106890121 A CN 106890121A CN 201710122125 A CN201710122125 A CN 201710122125A CN 106890121 A CN106890121 A CN 106890121A
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China
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parts
chinese medicine
water
solution
multifunctional
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CN201710122125.5A
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CN106890121B (en
Inventor
熊延靖
陈京
蔡天鑫
杨雅倩
刘安
方毓楠
陈从改
臧开林
尚昌懿
朱妮莎
张雅
熊峰
汪大伟
陶枫
陈雨婷
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Jiangsu Chenpai Bangde Pharmaceutical Co ltd
Shenzhen Morning Intellectual Property Operations Co ltd
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Wannan Medical College
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses a kind of multifunctional gargle and preparation method thereof, mouthwash includes the component of following mass percent:75 90% basic material mixed liquors and 10 25% Chinese medicine extracts;The basic material mixed liquor includes each component of following mass percent:2 3% NMFs, 0.4 1.5% sweetener, 0.05 0.1% preservative, 0.08 0.1% spices, 0.2 0.4% freshener, 0.1 0.2% sesame oil, 0.1 0.3% sodium chloride, 0.5 0.7% honey, balance of water;The component of Chinese medicine extract has:Honeysuckle, the capsule of weeping forsythia, lotus nut, Jin Lan, dandelion, Oroxylum indicum, the sterculia seed, matrimony vine.The present invention can effectively administer canker sore, slow down swelling and aching of gum, have reduce internal heat, the effect of fresh breath.

Description

A kind of multifunctional gargle and preparation method thereof
Technical field
The invention belongs to oral care implement technical field, and in particular to a kind of multifunctional gargle and preparation method thereof.
Background technology
With the development of modern society, interpersonal exchange also seems more and more frequently, and canker sore, gum are swollen Bitterly, the oral problem such as halitosis also turns into all the more comfortable exchange and hinders.Brush teeth accordingly, although the solution such as chew gum can reach To certain effect, but not enough facilitate, it is not ideal enough.Mouthwash becomes the object for extensive concern, and it is convenient, fast, takes effect Hurry up.But mouthwash on the market is unable to long-term use now, and bacterium can also produce corresponding drug resistance, and long-term use can Can trigger other oral problems, such as mucous membrane of mouth comes off or even allergic reaction.How active ingredient of Chinese herbs is added, it is and corresponding Chemical agent complements each other, and being combined using Chinese and Western makes the more long-term use of water energy of gargling of gained without producing side effect, is We need the problem for considering and solving.
The content of the invention
It is contemplated that at least solving one of technical problem present in prior art.Therefore, the present invention provides a kind of many Functional mouthwash and preparation method thereof, it is therefore an objective to the effect with treatment canker sore while making mouthwash that there is fresh breath Really.
To achieve these goals, the technical scheme taken of the present invention is:
A kind of multifunctional gargle, including following mass percent component:
75-90% basic materials mixed liquor and 10-25% Chinese medicine extracts;
The basic material mixed liquor includes each component of following mass percent:
2-3% NMFs, 0.4-1.5% sweeteners, 0.05-0.1% preservatives, 0.08-0.1% spices, 0.2-0.4% Freshener, 0.1-0.2% sesame oil, 0.1-0.3% sodium chloride, 0.5-0.7% honey, balance of water;
The Chinese medicine extract includes the raw material of following weight portion:
Honeysuckle 37-45 parts, capsule of weeping forsythia 22-28 parts, lotus nut 10-15 parts, Jin Lan 8-12 parts, dandelion 10-15 parts, wooden butterfly Butterfly 20-25 parts, sterculia seed 10-15 parts, matrimony vine 8-12 parts.
Preferably, the Chinese medicine extract includes the raw material of following weight portion:
40 parts of honeysuckle, 25 parts of the capsule of weeping forsythia, 15 parts of lotus nut, 10 parts of Jin Lan, 15 parts of dandelion, 25 parts of Oroxylum indicum, the sterculia seed 10 parts, 10 parts of matrimony vine.
The NMF includes glycerine and sorbierite, and glycerine is 1.5-2 with the mass ratio of sorbierite:1.
The sweetener includes xylitol and saccharin sodium, and the xylitol is 3-10 with the mass ratio of saccharin sodium:1.
The freshener includes borneol and menthol, and the borneol is 2 with the mass ratio of menthol:1.
The preparation method of the multifunctional gargle, comprises the following steps:
(1) honeysuckle of formula ratio, the capsule of weeping forsythia, lotus nut, Jin Lan, dandelion, Oroxylum indicum, the sterculia seed, matrimony vine are constituted Chinese medicine mixture extracting in water 2-3 times, adds 6-8 times and measures water, merging filtrate, through being concentrated under reduced pressure into Chinese medicine mixture every time 2-4 times of weight, obtains Chinese medicine extract;
(2) NMF of formula ratio is added to the water, sweetener, preservative and the spices of formula ratio is added after stirring, stirred Solution A is obtained after mixing;
(3) freshener of formula ratio, sesame oil, sodium chloride and honey are added to the water, B solution is obtained after stirring;
(4) solution A is mixed into obtain C solution with B solution;
(5) take obtained in step (1) during Chinese medicine extract adds C solution, it is agitated, stand, after the constant volume that adds water, obtain final product and gargle Saliva;The cumulative volume for wherein being added water in step (2) and step (3) is the 5/8 of mouthwash cumulative volume.
The addition of step (5) Chinese medicine extract is the 1/3 of step (1) gained Chinese medicine extract volume.
Step (2) is 10 with the volume ratio of amount of water in step (3):9.
Being concentrated under reduced pressure described in step (1) is concentrated using vacuum decompressioning and concentrating tank.
Herbal nature used of the invention is as follows:
Honeysuckle property sweet cold air fragrance, clear heat with drugs of sweet flavour and cold nature without hindering lung, fragrance thoroughly up to can get rid of evils again, it can dispelling wind-heat, Also it is apt to removing summer-heat blood poison, can be used for various febrile diseases, such as body heat, dermexanthesis, hair spot, carbuncle swells furunculosis, larynx numbness, erysipelas, toxic-heat and blood stasis, wind Thermal sensation emits, warm disease heating etc..
Capsule of weeping forsythia bitter cool in nature, it is light clear to float, all heat of the part of the body cavity above the diaphragm housing the heart and lungs can be controlled, especially can removing toxicity for eliminating carbuncles and dissipating bind, be equipped with honeysuckle flower, thin Lotus, schizonepeta, Radix Glycyrrhizae, then dissipate wind heat-clearing, and honeysuckle has good antipyretic and antidote functions with the capsule of weeping forsythia, can be diathermanous up to table, and energy Heat, solution sore in clear, therefore clinically two medicines are often with use.Honeysuckle can still remove heat from the blood and relieve diarrhea;The capsule of weeping forsythia can clear away heart-fire heat again, and dissipating bind disappears Scrofula.
Matrimony vine property sugariness is put down, with nourishing liver and kidney, effect of benefiting shrewd head.For consumption consumptive loss, soreness of waist and knee joint, dizziness ear Ring, Heat Diabetes, blood deficiency chlorosis, blurred vision.
The sweet cold bitter of dandelion property, with clearing heat and detoxicating, dispersing swelling and dissipating binds, effect of inducing diuresis for treating strangurtia, for furuncle swelling toxin, breast Carbuncle, scrofula, hot eyes, pharyngalgia, lung carbuncle, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.
It is Oroxylum indicum taste micro-sweet, hardship, cool in nature, with removing heat from the lung and relieving sorethroat, effect of soothing liver and harmonizing stomach, for cough with lung heat, larynx numbness, sound It is mute, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.
The sterculia seed is sweet, cold in nature, and with clearing heat and moistening lung, liyan jiedu relaxes bowel.For lung heat celostomia, dry cough without phlegm, Pharyngodynia with dryness, thermojunction is just closed, hot eyes of having a headache.
It is lotus nut bitter, cold in nature, with clearing away heart-fire, reduce phlegm and internal heat, effect of hemostasis,《This leather is new again》Described in lotus nut can clear away heart-fire Fire, soothing the liver fire rushes down spleen fire, drops lung-fire, and relieving restlessness of relieving summer heat, raw rule is quenched the thirst, and controls mesh red and swollen.
Jin Lan:It is sweet, it is cold in nature;Return liver warp.Heat-clearing, purging intense heat, removing toxic substances.Abscess of throat is cured mainly, is had a toothache, venomous snake bite.《Xinhua Herbal outline》Carry:" herb has heat-clearing, the function of purging intense heat.For having sore throat, having a toothache.
Beneficial effects of the present invention:Multifunctional gargle prepared by the present invention, adds active ingredient of Chinese herbs, with corresponding chemical Medicament complements each other, and being combined using Chinese and Western makes the more long-term use of water energy of gargling of gained without producing side effect.The present invention Canker sore can effectively be administered, slow down swelling and aching of gum, have reduce internal heat, the effect of fresh breath.
Specific embodiment
Below by the description to embodiment, specific embodiment of the invention is described in further detail, purpose Be to aid in those skilled in the art has more complete, accurate and deep understanding to design of the invention, technical scheme, and helps In its implementation.
A kind of multifunctional gargle, including following mass percent component:
75-90% basic materials mixed liquor and 10-25% Chinese medicine extracts;
Wherein, basic material mixed liquor includes each component of following mass percent:
2-3% NMFs, 0.4-1.5% sweeteners, 0.05-0.1% preservatives, 0.08-0.1% spices, 0.2-0.4% Freshener, 0.1-0.2% sesame oil, 0.1-0.3% sodium chloride, 0.5-0.7% honey, balance of water;
Chinese medicine extract includes the raw material of following weight portion:
Honeysuckle 37-45 parts, capsule of weeping forsythia 22-28 parts, lotus nut 10-15 parts, Jin Lan 8-12 parts, dandelion 10-15 parts, wooden butterfly Butterfly 20-25 parts, sterculia seed 10-15 parts, matrimony vine 8-12 parts.It is described in detail using preferred embodiment below.
Embodiment 1
A kind of multifunctional gargle, its preparation method comprises the following steps:
1st, the preparation of Chinese medicine extract:
(1) extracting honeysuckle 40g, capsule of weeping forsythia 25g, lotus nut 15g, Jin Lan 10g, dandelion 15g, Oroxylum indicum 25g, the sterculia seed 10g, matrimony vine 10g, refluxing extraction 2 times first soak 1.5h in water before refluxing extraction, add 1000ml water to extract 3h for the first time, Second plus 1000ml water extraction 3h, filter residue is taken out, merge filtrate twice;
(2) filtrate after above-mentioned merging is transferred in vacuum concentration pot and is decompressed to 1150Pa, be concentrated in vacuo to 300ml standby With;
2nd, the preparation of basic material mixed liquor:
(1) 10.6g glycerine, 5.3g sorbierites are dissolved in 263ml deionized waters, after stirring, continuously add 1.59g xyloses Alcohol, 0.53g saccharin sodiums, 1.06g potassium sorbates, 0.27g spearmints material, 0.27g peppermints, are stirred continuously 8min, obtain solution A;
(2) 1.06g borneols, 0.53g menthols, 1.06g sesame oil, 1.06g sodium chloride and 3.18g honey are added into 237ml In deionized water, 8min is stirred continuously, obtains B solution;
(3) solution A is well mixed to obtain C solution with B solution;
(4) take during the above-mentioned Chinese medicine extracts of 100ml add C solution, be stirred continuously 12min, 5min is stood afterwards, spend from Sub- water is settled to 800ml, obtains final product mouthwash.
Embodiment 2
A kind of multifunctional gargle, its preparation method comprises the following steps:
1st, the preparation of Chinese medicine extract:
(1) extracting honeysuckle 37g, capsule of weeping forsythia 22g, lotus nut 10g, Jin Lan 10g, dandelion 8g, Oroxylum indicum 20g, the sterculia seed 11g, matrimony vine 10g, refluxing extraction 2 times first soak 1h in water before refluxing extraction, add 950ml water to extract 3h, second for the first time Secondary plus 950ml water extracts 3h, and filter residue is taken out, and merges filtrate twice;
(2) filtrate after above-mentioned merging is transferred in vacuum concentration pot and is decompressed to 1100Pa, be concentrated in vacuo to 300ml standby With;
2nd, the preparation of basic material mixed liquor:
(1) 7.95g glycerine, 4.24g sorbierites are dissolved in 263ml deionized waters, after stirring, continuously add 5.3g xyloses Alcohol, 0.53g saccharin sodiums, 1.06g potassium sorbates, 0.27g spearmints material, 0.27g peppermints, are stirred continuously 6min, obtain solution A;
(2) 1.06g borneols, 0.53g menthols, 1.06g sesame oil, 1.06g sodium chloride and 3.18g honey are added into 237ml In deionized water, 6min is stirred continuously, obtains B solution;
(3) solution A is well mixed to obtain C solution with B solution;
(4) take during the above-mentioned Chinese medicine extracts of 100ml add C solution, be stirred continuously 10min, 5min is stood afterwards, spend from Sub- water is settled to 800ml, obtains final product mouthwash.
Embodiment 3
A kind of multifunctional gargle, its preparation method comprises the following steps:
1st, the preparation of Chinese medicine extract:
(1) extracting honeysuckle 45g, capsule of weeping forsythia 28g, lotus nut 15g, Jin Lan 12g, dandelion 15g, Oroxylum indicum 25g, the sterculia seed 15g, matrimony vine 12g, refluxing extraction 2 times first soak 1h in water before refluxing extraction, add 1100ml water to extract 3h for the first time, the Secondary plus 1100ml water extracts 3h, and filter residue is taken out, and merges filtrate twice;
(2) filtrate after above-mentioned merging is transferred in vacuum concentration pot and is decompressed to 1200Pa, be concentrated in vacuo to 300ml standby With;
2nd, the preparation of basic material mixed liquor:
(1) 7.95g glycerine, 4.24g sorbierites are dissolved in 263ml deionized waters, after stirring, continuously add 2.65g wood Sugar alcohol, 0.53g saccharin sodiums, 1.06g potassium sorbates, 1.59g spearmints material, 1.59g peppermints, are stirred continuously 6min, obtain A molten Liquid;
(2) 1.06g borneols, 0.53g menthols, 1.06g sesame oil, 1.06g sodium chloride and 3.18g honey are added into 237ml In deionized water, 6min is stirred continuously, obtains B solution;
(3) solution A is well mixed to obtain C solution with B solution;
(4) take during the above-mentioned Chinese medicine extracts of 100ml add C solution, be stirred continuously 10min, 5min is stood afterwards, spend from Sub- water is settled to 800ml, obtains final product mouthwash.
Resultant effect is tested
Following with the mouthwash for evaluating using rear effect embodiment 1-3 preparations.Canker sore is often suffered from 30 With the patient of swelling and aching of gum as on probation to being arbitrarily divided into three groups;The mouthwash for being prepared using embodiment 1-3 respectively, one day 3 Secondary, respectively respectively once using a week, every effect total score is 5 points morning, the morning, evening:5 points is best result, is represented Very well, very satisfied, effect is very good;4 points is preferable;3 points is to receive;Less than 3 points is bad, it is impossible to received.Below It is every average, concrete outcome is as shown in table 1 below.
The resultant effect of table 1 investigates result
In sum, the mouthwash that prepared by the present invention has preferable mouthfeel, is imitated with preferable breath freshening after use Really, can effectively administer canker sore, slow down swelling and aching of gum.
The present invention is exemplarily described above.Obviously, the present invention is implemented and is not subject to the restrictions described above. As long as employ the improvement of the various unsubstantialities that method of the present invention design and technical scheme are carried out;Or it is not improved, will Above-mentioned design of the invention and technical scheme directly apply to other occasions, within protection scope of the present invention.

Claims (9)

1. a kind of component of multifunctional gargle, including following mass percent:
75-90% basic materials mixed liquor and 10-25% Chinese medicine extracts;
The basic material mixed liquor includes each component of following mass percent:
2-3% NMFs, 0.4-1.5% sweeteners, 0.05-0.1% preservatives, 0.08-0.1% spices, 0.2-0.4% are refrigerant Agent, 0.1-0.2% sesame oil, 0.1-0.3% sodium chloride, 0.5-0.7% honey, balance of water;
The Chinese medicine extract includes the raw material of following weight portion:
Honeysuckle 37-45 parts, capsule of weeping forsythia 22-28 parts, lotus nut 10-15 parts, Jin Lan 8-12 parts, dandelion 10-15 parts, Oroxylum indicum 20-25 parts, sterculia seed 10-15 parts, matrimony vine 8-12 parts.
2. multifunctional gargle according to claim 1, it is characterised in that the Chinese medicine extract includes following weight portion Raw material:
40 parts of honeysuckle, 25 parts of the capsule of weeping forsythia, 15 parts of lotus nut, 10 parts of Jin Lan, 15 parts of dandelion, 25 parts of Oroxylum indicum, 10 parts of the sterculia seed, 10 parts of matrimony vine.
3. multifunctional gargle according to claim 1, it is characterised in that the NMF includes glycerine and sorbierite, sweet Oil is 1.5-2 with the mass ratio of sorbierite:1.
4. multifunctional gargle according to claim 1, it is characterised in that the sweetener includes xylitol and saccharin sodium, The xylitol is 3-10 with the mass ratio of saccharin sodium:1.
5. multifunctional gargle according to claim 1, it is characterised in that the freshener includes borneol and menthol, institute It is 2 that borneol is stated with the mass ratio of menthol:1.
6. according to claim any one of 1-5 multifunctional gargle preparation method, it is characterised in that including following step Suddenly:
(1) Chinese medicine for constituting the honeysuckle of formula ratio, the capsule of weeping forsythia, lotus nut, Jin Lan, dandelion, Oroxylum indicum, the sterculia seed, matrimony vine Material mixture extracting in water 2-3 times, adds 6-8 times and measures water, merging filtrate, through being concentrated under reduced pressure into Chinese medicine mixture weight every time 2-4 times, obtain Chinese medicine extract;
(2) NMF of formula ratio is added to the water, sweetener, preservative and the spices of formula ratio is added after stirring, after stirring Obtain solution A;
(3) freshener of formula ratio, sesame oil, sodium chloride and honey are added to the water, B solution is obtained after stirring;
(4) solution A is mixed into obtain C solution with B solution;
(5) take obtained in step (1) during Chinese medicine extract adds C solution, it is agitated, stand, after the constant volume that adds water, obtain final product and gargle Water;The cumulative volume for wherein being added water in step (2) and step (3) is the 5/8 of mouthwash cumulative volume.
7. the preparation method of multifunctional gargle according to claim 6, it is characterised in that step (5) Chinese medicine extract Addition is the 1/3 of step (1) gained Chinese medicine extract volume.
8. the preparation method of multifunctional gargle according to claim 6, it is characterised in that in step (2) and step (3) plus The volume ratio of water is 10:9.
9. the preparation method of multifunctional gargle according to claim 6, it is characterised in that step depressurizes dense described in (1) Contracting is concentrated using vacuum decompressioning and concentrating tank.
CN201710122125.5A 2017-03-03 2017-03-03 Multifunctional mouthwash and preparation method thereof Active CN106890121B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710122125.5A CN106890121B (en) 2017-03-03 2017-03-03 Multifunctional mouthwash and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710122125.5A CN106890121B (en) 2017-03-03 2017-03-03 Multifunctional mouthwash and preparation method thereof

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Publication Number Publication Date
CN106890121A true CN106890121A (en) 2017-06-27
CN106890121B CN106890121B (en) 2020-04-21

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107184496A (en) * 2017-07-30 2017-09-22 何家平 A kind of fig toothwash hydraulic art
CN107811913A (en) * 2017-11-14 2018-03-20 名臣健康用品股份有限公司 A kind of application of Chinese medicine composition in oral care product

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Publication number Priority date Publication date Assignee Title
CN105326742A (en) * 2015-11-12 2016-02-17 厉政轩 Anti-infective and antibacterial mouth wash and preparation method thereof
CN106265423A (en) * 2016-08-23 2017-01-04 广州立白企业集团有限公司 Having relieves inflammation or internal heat disappear pain effect oral care composition
CN106420497A (en) * 2016-11-25 2017-02-22 江苏爱西施科技服务咨询股份有限公司 Fibroin mouth wash and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105326742A (en) * 2015-11-12 2016-02-17 厉政轩 Anti-infective and antibacterial mouth wash and preparation method thereof
CN106265423A (en) * 2016-08-23 2017-01-04 广州立白企业集团有限公司 Having relieves inflammation or internal heat disappear pain effect oral care composition
CN106420497A (en) * 2016-11-25 2017-02-22 江苏爱西施科技服务咨询股份有限公司 Fibroin mouth wash and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107184496A (en) * 2017-07-30 2017-09-22 何家平 A kind of fig toothwash hydraulic art
CN107811913A (en) * 2017-11-14 2018-03-20 名臣健康用品股份有限公司 A kind of application of Chinese medicine composition in oral care product

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