CN105326742A - Anti-infective and antibacterial mouth wash and preparation method thereof - Google Patents
Anti-infective and antibacterial mouth wash and preparation method thereof Download PDFInfo
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- CN105326742A CN105326742A CN201510768649.2A CN201510768649A CN105326742A CN 105326742 A CN105326742 A CN 105326742A CN 201510768649 A CN201510768649 A CN 201510768649A CN 105326742 A CN105326742 A CN 105326742A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Abstract
The invention discloses anti-infective and antibacterial mouth wash and a preparation method thereof. The anti-infective and antibacterial mouth wash is mainly prepared from honeysuckle, centella, sodium chloride, wasabi oil, grape procyanidins, sorbitol, stevioside, glycerol, ethyl parahydroxybenzoate, sodium carboxymethylcellulose, borneol, vinegar, vitamin C, edible grade ethyl alcohol, anti-infective and antibacterial auxiliaries and purified water. According to the mouth wash, the honeysuckle, the centella and the other various traditional Chinese medicine components are adopted, the tooth cleaning effect is good, the anti-infective and anti-blooding can be achieved, the vinegar and the anti-infective and antibacterial auxiliaries are used in a cooperative mode, the antibacterial effect is good, and no irritability reaction is caused, and the mouth is kept clean and sanitary.
Description
Technical field
The present invention relates to daily chemical product technical field, is more particularly a kind of antiphlogistic antibacterial collutory and preparation method thereof.
Background technology
Collutory key component is essence, surfactant, fluoride, strontium chloride, ethanol and water etc., energy cleaning oral cavity, caries prevention and periodontitis etc.Collutory has deep or light two kinds, and dense dilutes rear use with water, and light can directly gargle.
It is believed that brushes teeth in the past sooner or later just can reach sanitary standard, but can be nowhere near with regard to oral hygiene new concept.Expert proposes: cleaning oral cavity is required as washing one's hands.But take out toothpaste whenever and wherever possible, but toothbrush is unrealistic, at this moment collutory just can stand up and volunteer to help, and takes on heavy burden, and anytime anywhere it can be your cleaning oral cavity, refusal residue on teeth erosion; Moreover have meal in some occasions, containing the cuisines that Herba Alii fistulosi, Bulbus Allii etc. are highly seasoned, make you " try to stop but cannot ", but do not have no idea, a standby small vial of mouthwash, only need go to time toilet, ability to speak is pure and fresh at once, without vestige, you can be glutted oneself with delicacies to the greatest extent; Secondly, in travelling way, water tank lacks water or all often have with water is crowded, for bottle collutory, all worries one have gargled it; In addition, collutory will be also the old man of loss of tooth, the child that can not brush teeth and the optimum selection being impatient at dental patient's oral hygiene guarantee of brushing teeth.
Traditional collutory contains more ethanol, has certain harm to oral cavity, and portioned product, for reaching ideal effect, is not stinted and added chemosynthesis reagent, to improve the effect of collutory, and this way, concerning user, there is very large potential safety hazard.
Summary of the invention
The object of the invention is to make up the deficiencies in the prior art, a kind of antiphlogistic antibacterial collutory and preparation method thereof is provided.
The object of the invention is to be achieved through the following technical solutions:
A kind of antiphlogistic antibacterial collutory, is made up of following raw material: Flos Lonicerae 2-4, Herba Centellae 2-3, sodium chloride 1-2, Wasabia japonic (Euterma Wasabi) quintessence oil 0.5-1, grape polyphenols 2-3, Sorbitol 1-2, stevioside 1-2, glycerol 1-3, Buddhist nun moor second gold ester 1-2, sodium carboxymethyl cellulose 0.5-1, Borneolum Syntheticum 2-3, vinegar 1-2, vitamin c 0.4-0.6, food grade ethanol 4-6, antiphlogistic antibacterial auxiliary agent 3-4, pure water 80-100; Wherein antiphlogistic antibacterial auxiliary agent is made up of following raw material: Rhizoma Coptidis 2-4, Bulbus Allii juice 1-2, Mel 0.5-1, red wine 0.6-0.8, carase 0.5-0.7, Folium Perillae 1-2, pollen 0.2-0.4, sodium fluoride 1-2, erythromycin 0.5-1, Herba Lophatheri 3-5; Preparation method is: take the Rhizoma Coptidis of described parts by weight, Herba Lophatheri, Folium Perillae, decoct with water twice, and each amount of water was advisable not have powder; First time decocts continues to decoct 15-25 minute after seething with excitement, and second time decocts and continues to decoct 10-20 minute after seething with excitement, and considers and add water and stir 2-3 time during decoction; After decoction completes, merging decoction liquor obtains Chinese herbal medicine fluid; In Chinese herbal medicine fluid, add Bulbus Allii juice, Mel, red wine, carase, pollen, sodium fluoride, erythromycin at 40-50 DEG C, be incubated 20-30 minute after stirring and get final product.
A preparation method for antiphlogistic antibacterial collutory, be made up of following steps:
(1) Sorbitol, stevioside are stirred to dissolving in water, then add Buddhist nun and moor second gold ester, vinegar and stir to clarify transparent finely dispersed aqueous solution;
(2) add pure water by after Wasabia japonic (Euterma Wasabi) quintessence oil, grape polyphenols mixing, be heated to 30-50 DEG C, then stirring and dissolving is to clarification;
(3) Flos Lonicerae, Herba Centellae are put into pot after cleaning, add appropriate water, slow fire boiling, filter to obtain Chinese herbal medicine fluid;
(4) raw material of step (1), step (2) and step (3) gained is mixed, the raw materials such as sodium chloride, glycerol, sodium carboxymethyl cellulose, Borneolum Syntheticum, vitamin c, food grade ethanol, antiphlogistic antibacterial auxiliary agent are added in stirring, to continue to be stirred to evenly isothermal holding 30-40 minute at 35-40 DEG C, then leave standstill, filter, aseptic process and get final product.
The invention has the advantages that:
Collutory of the present invention adopts the plurality of Chinese such as Flos Lonicerae, Herba Centellae composition, and cleaning benefits is good, and can play the effect of anti-inflammation hemostasia, collocation vinegar, antiphlogistic antibacterial auxiliary agent use together, bactericidal effect is good, and can not cause allergic reaction, and contributes to the clean health keeping oral cavity.
Detailed description of the invention
Embodiment 1, a kind of antiphlogistic antibacterial collutory, is made up of following weight (kg) raw material: Flos Lonicerae 2, Herba Centellae 2, sodium chloride 1, Wasabia japonic (Euterma Wasabi) quintessence oil 0.5, grape polyphenols 2, Sorbitol 1, stevioside 1, glycerol 1, Buddhist nun moor second gold ester 1, sodium carboxymethyl cellulose 0.5, Borneolum Syntheticum 2, vinegar 1, vitamin c 0.4, food grade ethanol 4, antiphlogistic antibacterial auxiliary agent 3, pure water 80; Wherein antiphlogistic antibacterial auxiliary agent is made up of following raw material: Rhizoma Coptidis 2, Bulbus Allii juice 1, Mel 0.5, red wine 0.6, carase 0.5, Folium Perillae 1, pollen 0.2, sodium fluoride 1, erythromycin 0.5, Herba Lophatheri 3; Preparation method is: take the Rhizoma Coptidis of described parts by weight, Herba Lophatheri, Folium Perillae, decoct with water twice, and each amount of water was advisable not have powder; First time decocts continues decoction 15 minutes after seething with excitement, and second time decocts and continue decoction 10 minutes after seething with excitement, and considers and add water and stir 2 times during decoction; After decoction completes, merging decoction liquor obtains Chinese herbal medicine fluid; In Chinese herbal medicine fluid, add Bulbus Allii juice, Mel, red wine, carase, pollen, sodium fluoride, erythromycin at 40 DEG C, be incubated 20 minutes after stirring and get final product.
A preparation method for antiphlogistic antibacterial collutory, be made up of following steps:
(1) Sorbitol, stevioside are stirred to dissolving in water, then add Buddhist nun and moor second gold ester, vinegar and stir to clarify transparent finely dispersed aqueous solution;
(2) add pure water by after Wasabia japonic (Euterma Wasabi) quintessence oil, grape polyphenols mixing, be heated to 30 DEG C, then stirring and dissolving is to clarification;
(3) Flos Lonicerae, Herba Centellae are put into pot after cleaning, add appropriate water, slow fire boiling, filter to obtain Chinese herbal medicine fluid;
(4) raw material of step (1), step (2) and step (3) gained is mixed, the raw materials such as sodium chloride, glycerol, sodium carboxymethyl cellulose, Borneolum Syntheticum, vitamin c, food grade ethanol, antiphlogistic antibacterial auxiliary agent are added in stirring, to continue to be stirred to evenly at 35 DEG C isothermal holding 30 minutes, then leave standstill, filter, aseptic process and get final product.
Embodiment 2, a kind of antiphlogistic antibacterial collutory, is made up of following weight (kg) raw material: Flos Lonicerae 3, Herba Centellae 2, sodium chloride 1, Wasabia japonic (Euterma Wasabi) quintessence oil 0.8, grape polyphenols 2, Sorbitol 2, stevioside 1, glycerol 2, Buddhist nun moor second gold ester 1, sodium carboxymethyl cellulose 0.7, Borneolum Syntheticum 3, vinegar 1, vitamin c 0.5, food grade ethanol 5, antiphlogistic antibacterial auxiliary agent 3, pure water 90; Wherein antiphlogistic antibacterial auxiliary agent is made up of following raw material: Rhizoma Coptidis 3, Bulbus Allii juice 2, Mel 0.8, red wine 0.7, carase 0.6, Folium Perillae 2, pollen 0.3, sodium fluoride 1, erythromycin 0.8, Herba Lophatheri 4; Preparation method is: take the Rhizoma Coptidis of described parts by weight, Herba Lophatheri, Folium Perillae, decoct with water twice, and each amount of water was advisable not have powder; First time decocts continues decoction 20 minutes after seething with excitement, and second time decocts and continue decoction 15 minutes after seething with excitement, and considers and add water and stir 2 times during decoction; After decoction completes, merging decoction liquor obtains Chinese herbal medicine fluid; In Chinese herbal medicine fluid, add Bulbus Allii juice, Mel, red wine, carase, pollen, sodium fluoride, erythromycin at 45 DEG C, be incubated 25 minutes after stirring and get final product.
A preparation method for antiphlogistic antibacterial collutory, be made up of following steps:
(1) Sorbitol, stevioside are stirred to dissolving in water, then add Buddhist nun and moor second gold ester, vinegar and stir to clarify transparent finely dispersed aqueous solution;
(2) add pure water by after Wasabia japonic (Euterma Wasabi) quintessence oil, grape polyphenols mixing, be heated to 40 DEG C, then stirring and dissolving is to clarification;
(3) Flos Lonicerae, Herba Centellae are put into pot after cleaning, add appropriate water, slow fire boiling, filter to obtain Chinese herbal medicine fluid;
(4) raw material of step (1), step (2) and step (3) gained is mixed, the raw materials such as sodium chloride, glycerol, sodium carboxymethyl cellulose, Borneolum Syntheticum, vitamin c, food grade ethanol, antiphlogistic antibacterial auxiliary agent are added in stirring, to continue to be stirred to evenly at 38 DEG C isothermal holding 35 minutes, then leave standstill, filter, aseptic process and get final product.
Embodiment 3, a kind of antiphlogistic antibacterial collutory, is made up of following weight (kg) raw material: Flos Lonicerae 4, Herba Centellae 3, sodium chloride 2, Wasabia japonic (Euterma Wasabi) quintessence oil 1, grape polyphenols 3, Sorbitol 2, stevioside 2, glycerol 3, Buddhist nun moor second gold ester 2, sodium carboxymethyl cellulose 1, Borneolum Syntheticum 3, vinegar 2, vitamin c 0.6, food grade ethanol 6, antiphlogistic antibacterial auxiliary agent 4, pure water 100; Wherein antiphlogistic antibacterial auxiliary agent is made up of following raw material: Rhizoma Coptidis 4, Bulbus Allii juice 2, Mel 1, red wine 0.8, carase 0.7, Folium Perillae 2, pollen 0.4, sodium fluoride 2, erythromycin 1, Herba Lophatheri 5; Preparation method is: take the Rhizoma Coptidis of described parts by weight, Herba Lophatheri, Folium Perillae, decoct with water twice, and each amount of water was advisable not have powder; First time decocts continues decoction 25 minutes after seething with excitement, and second time decocts and continue decoction 20 minutes after seething with excitement, and considers and add water and stir 3 times during decoction; After decoction completes, merging decoction liquor obtains Chinese herbal medicine fluid; In Chinese herbal medicine fluid, add Bulbus Allii juice, Mel, red wine, carase, pollen, sodium fluoride, erythromycin at 50 DEG C, be incubated 30 minutes after stirring and get final product.
A preparation method for antiphlogistic antibacterial collutory, be made up of following steps:
(1) Sorbitol, stevioside are stirred to dissolving in water, then add Buddhist nun and moor second gold ester, vinegar and stir to clarify transparent finely dispersed aqueous solution;
(2) add pure water by after Wasabia japonic (Euterma Wasabi) quintessence oil, grape polyphenols mixing, be heated to 50 DEG C, then stirring and dissolving is to clarification;
(3) Flos Lonicerae, Herba Centellae are put into pot after cleaning, add appropriate water, slow fire boiling, filter to obtain Chinese herbal medicine fluid;
(4) raw material of step (1), step (2) and step (3) gained is mixed, the raw materials such as sodium chloride, glycerol, sodium carboxymethyl cellulose, Borneolum Syntheticum, vitamin c, food grade ethanol, antiphlogistic antibacterial auxiliary agent are added in stirring, to continue to be stirred to evenly at 40 DEG C isothermal holding 40 minutes, then leave standstill, filter, aseptic process and get final product.
The main performance testing result of the antiphlogistic antibacterial collutory that above-described embodiment 1-3 obtains is as shown in the table:
The main performance testing result of the antiphlogistic antibacterial collutory that table 1 embodiment 1-3 obtains
To tooth yellowing person effective percentage % | To tooth yellowing person effective percentage % | To red and swollen bleeder's effective percentage | |
Embodiment 1 | 76 | 72 | 66 |
Embodiment 2 | 80 | 76 | 64 |
Embodiment 3 | 78 | 75 | 65 |
Claims (2)
1. an antiphlogistic antibacterial collutory, is characterized in that: be made up of following raw material: Flos Lonicerae 2-4, Herba Centellae 2-3, sodium chloride 1-2, Wasabia japonic (Euterma Wasabi) quintessence oil 0.5-1, grape polyphenols 2-3, Sorbitol 1-2, stevioside 1-2, glycerol 1-3, Buddhist nun moor second gold ester 1-2, sodium carboxymethyl cellulose 0.5-1, Borneolum Syntheticum 2-3, vinegar 1-2, vitamin c 0.4-0.6, food grade ethanol 4-6, antiphlogistic antibacterial auxiliary agent 3-4, pure water 80-100; Wherein antiphlogistic antibacterial auxiliary agent is made up of following raw material: Rhizoma Coptidis 2-4, Bulbus Allii juice 1-2, Mel 0.5-1, red wine 0.6-0.8, carase 0.5-0.7, Folium Perillae 1-2, pollen 0.2-0.4, sodium fluoride 1-2, erythromycin 0.5-1, Herba Lophatheri 3-5; Preparation method is: take the Rhizoma Coptidis of described parts by weight, Herba Lophatheri, Folium Perillae, decoct with water twice, and each amount of water was advisable not have powder; First time decocts continues to decoct 15-25 minute after seething with excitement, and second time decocts and continues to decoct 10-20 minute after seething with excitement, and considers and add water and stir 2-3 time during decoction; After decoction completes, merging decoction liquor obtains Chinese herbal medicine fluid; In Chinese herbal medicine fluid, add Bulbus Allii juice, Mel, red wine, carase, pollen, sodium fluoride, erythromycin at 40-50 DEG C, be incubated 20-30 minute after stirring and get final product.
2. the preparation method of a kind of antiphlogistic antibacterial collutory according to claim 1, is characterized in that: be made up of following steps:
(1) Sorbitol, stevioside are stirred to dissolving in water, then add Buddhist nun and moor second gold ester, vinegar and stir to clarify transparent finely dispersed aqueous solution;
(2) add pure water by after Wasabia japonic (Euterma Wasabi) quintessence oil, grape polyphenols mixing, be heated to 30-50 DEG C, then stirring and dissolving is to clarification;
(3) Flos Lonicerae, Herba Centellae are put into pot after cleaning, add appropriate water, slow fire boiling, filter to obtain Chinese herbal medicine fluid;
(4) raw material of step (1), step (2) and step (3) gained is mixed, the raw materials such as sodium chloride, glycerol, sodium carboxymethyl cellulose, Borneolum Syntheticum, vitamin c, food grade ethanol, antiphlogistic antibacterial auxiliary agent are added in stirring, to continue to be stirred to evenly isothermal holding 30-40 minute at 35-40 DEG C, then leave standstill, filter, aseptic process and get final product.
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105919892A (en) * | 2016-06-21 | 2016-09-07 | 广西大学 | Hazelnut flavor mouth wash and preparation method thereof |
CN106074693A (en) * | 2016-07-29 | 2016-11-09 | 许备占 | Wild Hibisci Mutabilis mouth sprays |
CN106176315A (en) * | 2016-08-27 | 2016-12-07 | 广东罗浮山国药股份有限公司 | A kind of collutory and preparation method thereof |
CN106619284A (en) * | 2016-12-08 | 2017-05-10 | 西安中天生物医药有限公司 | Traditional Chinese medicine mouthwash for inhibiting bacteria in oral cavity and refreshing breath and preparation method thereof |
CN106890121A (en) * | 2017-03-03 | 2017-06-27 | 皖南医学院 | A kind of multifunctional gargle and preparation method thereof |
CN107320408A (en) * | 2017-06-30 | 2017-11-07 | 广西顺帆投资有限公司 | Mouthwash prepared by a kind of utilization banana skin and preparation method thereof |
CN113350239A (en) * | 2021-06-25 | 2021-09-07 | 山西工商学院 | Multifunctional mouthwash containing mature vinegar and preparation method of multifunctional mouthwash |
CN114376956A (en) * | 2022-02-24 | 2022-04-22 | 四川天福精细化工有限公司 | Spray mouth wash and preparation method thereof |
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Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105919892A (en) * | 2016-06-21 | 2016-09-07 | 广西大学 | Hazelnut flavor mouth wash and preparation method thereof |
CN106074693A (en) * | 2016-07-29 | 2016-11-09 | 许备占 | Wild Hibisci Mutabilis mouth sprays |
CN106176315A (en) * | 2016-08-27 | 2016-12-07 | 广东罗浮山国药股份有限公司 | A kind of collutory and preparation method thereof |
CN106176315B (en) * | 2016-08-27 | 2019-03-12 | 广东罗浮山国药股份有限公司 | A kind of mouthwash and preparation method thereof |
CN106619284A (en) * | 2016-12-08 | 2017-05-10 | 西安中天生物医药有限公司 | Traditional Chinese medicine mouthwash for inhibiting bacteria in oral cavity and refreshing breath and preparation method thereof |
CN106890121A (en) * | 2017-03-03 | 2017-06-27 | 皖南医学院 | A kind of multifunctional gargle and preparation method thereof |
CN107320408A (en) * | 2017-06-30 | 2017-11-07 | 广西顺帆投资有限公司 | Mouthwash prepared by a kind of utilization banana skin and preparation method thereof |
CN113350239A (en) * | 2021-06-25 | 2021-09-07 | 山西工商学院 | Multifunctional mouthwash containing mature vinegar and preparation method of multifunctional mouthwash |
CN114376956A (en) * | 2022-02-24 | 2022-04-22 | 四川天福精细化工有限公司 | Spray mouth wash and preparation method thereof |
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