CN106794205B - 益生菌的抗菌裂解物 - Google Patents

益生菌的抗菌裂解物 Download PDF

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Publication number
CN106794205B
CN106794205B CN201580028700.4A CN201580028700A CN106794205B CN 106794205 B CN106794205 B CN 106794205B CN 201580028700 A CN201580028700 A CN 201580028700A CN 106794205 B CN106794205 B CN 106794205B
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China
Prior art keywords
staphylococcus aureus
bacteria
keratinocytes
lactobacillus rhamnosus
lysate
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CN201580028700.4A
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English (en)
Chinese (zh)
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CN106794205A (zh
Inventor
凯瑟琳·奥尼尔
安德鲁·麦克贝恩
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Skin Biotherapy Ltd
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Skin Biotherapy Ltd
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Publication of CN106794205A publication Critical patent/CN106794205A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
CN201580028700.4A 2014-05-29 2015-05-26 益生菌的抗菌裂解物 Active CN106794205B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1409541.8A GB201409541D0 (en) 2014-05-29 2014-05-29 Probiotic Bacteria
GB1409541.8 2014-05-29
PCT/GB2015/051529 WO2015181534A1 (en) 2014-05-29 2015-05-26 Anti-bacterial lysate of probiotic bacteria

Publications (2)

Publication Number Publication Date
CN106794205A CN106794205A (zh) 2017-05-31
CN106794205B true CN106794205B (zh) 2021-10-01

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CN201580028700.4A Active CN106794205B (zh) 2014-05-29 2015-05-26 益生菌的抗菌裂解物

Country Status (9)

Country Link
US (1) US10702562B2 (zh-TW)
EP (1) EP3148558B1 (zh-TW)
JP (1) JP6741595B2 (zh-TW)
CN (1) CN106794205B (zh-TW)
AU (1) AU2015265698B2 (zh-TW)
CA (1) CA2950510C (zh-TW)
ES (1) ES2842215T3 (zh-TW)
GB (1) GB201409541D0 (zh-TW)
WO (1) WO2015181534A1 (zh-TW)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201409541D0 (en) 2014-05-29 2014-07-16 Univ Manchester Probiotic Bacteria
GB2544481B (en) * 2015-11-16 2019-12-11 Century International Enterprises Ltd A wearable article and a method for producing a wearable article
GB201608762D0 (en) * 2016-05-18 2016-06-29 Skinbiotix Ltd Compositions and uses thereof
CL2017001273A1 (es) * 2017-05-17 2018-03-16 Univ San Sebastian Aerosol orofaríngeo compuesto por un hidrolizado derivado de un probiótico que tiene impacto en la inmunidad del tracto genitourinario, método de obtención del hidrolizado, composiciones farmacéuticas que lo contienen y uso de las mismas.
GB201807576D0 (en) 2018-05-09 2018-06-20 Skinbiotherapeutics Plc Compositions and uses thereof
CN112957404A (zh) * 2021-02-08 2021-06-15 广东广汇农牧有限公司 一种用于母猪阴道护理的环保型清洗液组合物及其制备方法
US11633348B2 (en) 2021-03-19 2023-04-25 Eligo Bioscience Cosmetic use of engineered postbiotics comprising bacteriocins and/or endolysins
WO2022195118A1 (en) * 2021-03-19 2022-09-22 Eligo Bioscience Therapeutic use of engineered postbiotics comprising bacteriocins and/or endolysins for treating cutaneous lymphoma
CN114717131B (zh) * 2021-09-07 2023-05-26 青岛蔚蓝生物股份有限公司 一株对皮肤损伤具有保护作用的鼠李糖乳杆菌及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012150269A1 (en) * 2011-05-03 2012-11-08 Dupont Nutrition Biosciences Aps Probiotic bacteria for the topical treatment of skin disorders
WO2013153358A1 (en) * 2012-04-13 2013-10-17 The University Of Manchester Probiotic bacteria

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070070153A (ko) * 2004-06-23 2007-07-03 로레알 민감성 및/또는 건성 피부의 예방 및/또는 치료에 유용한방법 및 조성물
US20110039765A1 (en) * 2008-04-17 2011-02-17 Connor Ruth I Bioactive Molecules Produced by Probiotic Bacteria
CA2765298A1 (en) * 2008-06-27 2009-12-30 University Of Guelph Probiotic bacterial molecules and their use in methods to treat/prevent infection by harmful bacteria and to provide nutritional health
GB201409541D0 (en) 2014-05-29 2014-07-16 Univ Manchester Probiotic Bacteria

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012150269A1 (en) * 2011-05-03 2012-11-08 Dupont Nutrition Biosciences Aps Probiotic bacteria for the topical treatment of skin disorders
WO2013153358A1 (en) * 2012-04-13 2013-10-17 The University Of Manchester Probiotic bacteria

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
"Inhibition of Salmonella typhimurium adhesion to Caco-2 cell cultures by Lactobacillus strain GG spent culture supernate: only a pH effect?";Elina M Lehto等;《FEMS Immunology and Medical Microbiology》;20060117;第18卷(第2期);第125-132页 *
"鼠李糖乳杆菌(ATTC53103)产细菌素的研究",,;吴光伟等;《中国食品添加剂》;20091031(第5期);第136-140、124页 *
"鼠李糖乳杆菌产生抗菌物质的抑菌作用和特性研究";刘冬梅等;《中国乳品工业》;20060131;第34卷(第1期);第13-16页 *
"鼠李糖乳杆菌的培养上清液对几个致病菌和腐败菌的抑菌作用研究";刘冬梅等;《食品研究与开发》;20061031(第10期);第67-72页 *
M1208 Six Small Bioactive Peptides Identified from Lactobacillus GG Cultured Supernatant;Lu R等;《Elsevier》;20080401;第134卷(第1期);第A361页 *
Strong antimicrobial activity of Lactobacillus rhamnosus GG against Salmonella typhimurium is due to accumulation of lactic acid.;De Keersmaecker SC1等;《FEMS Microbiol Lett》;20060421;第259卷(第1期);第89-96页 *
鼠李糖乳杆菌LT22代谢产物抑菌实验研究;刘颖等;《中国乳品工业》;20091031;第37卷(第10期);第27-29页 *

Also Published As

Publication number Publication date
JP2017519730A (ja) 2017-07-20
EP3148558A1 (en) 2017-04-05
JP6741595B2 (ja) 2020-08-19
US20170196919A1 (en) 2017-07-13
ES2842215T3 (es) 2021-07-13
AU2015265698A1 (en) 2016-12-22
GB201409541D0 (en) 2014-07-16
US10702562B2 (en) 2020-07-07
WO2015181534A1 (en) 2015-12-03
EP3148558B1 (en) 2020-10-28
CN106794205A (zh) 2017-05-31
CA2950510C (en) 2023-10-24
CA2950510A1 (en) 2015-12-03
AU2015265698B2 (en) 2020-10-22

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