CN106748958B - 一种Rucaparib中间体的制备方法 - Google Patents
一种Rucaparib中间体的制备方法 Download PDFInfo
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- CN106748958B CN106748958B CN201710055940.4A CN201710055940A CN106748958B CN 106748958 B CN106748958 B CN 106748958B CN 201710055940 A CN201710055940 A CN 201710055940A CN 106748958 B CN106748958 B CN 106748958B
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- 0 Cc(cc1)*(**)cc1F Chemical compound Cc(cc1)*(**)cc1F 0.000 description 4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
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CN201710055940.4A CN106748958B (zh) | 2017-01-25 | 2017-01-25 | 一种Rucaparib中间体的制备方法 |
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CN201710055940.4A CN106748958B (zh) | 2017-01-25 | 2017-01-25 | 一种Rucaparib中间体的制备方法 |
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CN106748958A CN106748958A (zh) | 2017-05-31 |
CN106748958B true CN106748958B (zh) | 2018-12-18 |
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Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107954919B (zh) * | 2018-01-08 | 2020-08-14 | 安庆奇创药业有限公司 | 一种Rucaparib关键中间体的制备方法 |
CN110229162B (zh) * | 2018-03-05 | 2020-08-11 | 新发药业有限公司 | 一种瑞卡帕布的简便制备方法 |
CN108752353B (zh) * | 2018-04-28 | 2020-05-08 | 程春晓 | 抗卵巢癌药物Rucaparib关键中间体1408282‐26‐7的制备方法 |
CN109180687A (zh) * | 2018-08-31 | 2019-01-11 | 山东轩德医药科技有限公司 | 一种瑞卡帕步中间体的制备方法 |
CN114133396B (zh) * | 2022-01-04 | 2023-07-21 | 浙江乐普药业股份有限公司 | 8-氟-1,3,4,5-四氢-氮杂卓并[5,4,3-cd]吲哚-6-酮的合成方法 |
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SI20691B (sl) * | 1999-01-11 | 2008-10-31 | Agouron Pharma | Triciklični inhibitorji poli(ADP-riboza) polimeraz |
ATE395393T1 (de) * | 2004-12-16 | 2008-05-15 | Sicpa Holding Sa | Cholestere monoschichten und monoschichtpigmente mit besonderen eigenschaften, deren herstellung und verwendung |
CN106008530B (zh) * | 2016-07-24 | 2018-06-26 | 石家庄久正生物科技有限公司 | 一种抗卵巢癌药物Rucaparib关键中间体的制备方法 |
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CB03 | Change of inventor or designer information |
Inventor after: Lun Junjie Inventor after: Sun Zongli Inventor after: Cao Geliang Inventor after: Chen Linghao Inventor before: Chen Linghao |
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Effective date of registration: 20181101 Address after: 262400 278 Limin street, Changle County, Weifang, Shandong Applicant after: Lun Junjie Address before: 266520 1 residential 1708, Changjiang East Road, Huangdao District, Qingdao, Shandong, 1708 Applicant before: Chen Da bio tech ltd, Qingdao |
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