CN106729085A - A kind of Chinese medicine composition for preventing and treating livestock and poultry cough and asthma and preparation method thereof - Google Patents
A kind of Chinese medicine composition for preventing and treating livestock and poultry cough and asthma and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The present invention relates to a kind of Chinese medicine composition for preventing and treating livestock and poultry cough and asthma and preparation method thereof, the Chinese medicine composition is prepared from by the Chinese medicine material medicine of following weight proportion, 150 250 parts of blackberry lily, 100 200 parts of subprostrate sophora, 100 200 parts of Lasiosphaera fenzlii, 50 150 parts of Chinese olive, 50 150 parts of Oroxylum indicum, 50 150 parts of fritillaria thunbergii, 50 150 parts of caulis bambusae in taenian, 20 80 parts of airpotato yam, 20 80 parts of the root bark of white mulberry.Synergy can be produced between its each raw material components, curative effect can be promoted each other, instant effect, without any toxic and side effect, the recurrence after healing can be avoided, and the Chinese medicine composition efficacy stability, not the impact effect because of overlong time.
Description
Technical field
The present invention relates in a kind of field of Chinese medicines for preventing and treating livestock and poultry, more particularly to a kind of preventing and treating livestock and poultry cough and asthma
Drug composition and preparation method thereof.
Background technology
Pig cough illness is a kind of chronic respiratory tract disease of the pig caused by mycoplasma hyopneumoniae, is called pig endemicity lung
Inflammation, is a kind of chronic lung disease of pig, and main clinic symptoms are to cough and pant.The sick initial stage is very brief, dry cough, while outflow is a small amount of
Serosity nose liquid, flows canescence mucus or purulence nose liquid when seriously ill, asthma phenomenon occurs in mid-term.Body temperature normally, appetite without
Significant change.Sick stage asthma is aggravated, and dehisces to breathe, and lassitude, pig body is become thin, and is reluctant to walk about.
Pig cough illness is most commonly seen with autumn and winter, and different cultivars, the pig at age can infect.Sucking pig is to be easiest to infection
, being in chronic process or subclinical infection next to that milking sow, Adult Pig more.The incidence of disease of pig cough and asthma is higher, and weight is expected after morbidity
Than increase, slow-growing, feed consumption rate also showed increased, feeding cost is caused to increase, economic loss is serious.Therefore, it is badly in need of a kind of
The Chinese medical extract of curative effect high, the preventing and treating piglet cough and asthma of low-residual, can effectively reduce cough and asthma, significantly reduce porcine respiratory disease
The incidence of disease.
Chicken is breathed with cough the extensive generation of disease (the dyspneic disease based on symptom of breathing with cough, be temporarily referred to as disease of breathing with cough), provisions
Chicken production causes larger economic loss.This course of disease is different in size, there is several days, Shi Jitian, or even is extended to and delivers for sale, bright
The aobvious economic benefit for reducing colony.Pathogenic factor is more because bacterium, virus, metabolism, raising are not good at causing.The present invention provides a kind of
Traditional Chinese medicine compound composition, it can reduce sucking pig cough and asthma number of times during large scale of pig farm, improve feed intake, enhancing food
It is intended to, can be applicable in large scale of pig farm factory.
The content of the invention
In order to solve the above problems, present invention aim at the Chinese medicine composition and its system that provide a kind of preventing and treating livestock and poultry cough and asthma
Preparation Method, the medical treatment livestock and poultry cough and asthma effect made using said composition is preferable, low cost.
To achieve the above object, the invention discloses a kind of Chinese medicine composition for preventing and treating livestock and poultry cough and asthma, the Chinese traditional medicine composition
Thing is prepared from by the Chinese medicine material medicine of following weight proportion, blackberry lily 150-250 parts, subprostrate sophora 100-200 parts, Lasiosphaera fenzlii 100-
200 parts, Chinese olive 50-150 parts, Oroxylum indicum 50-150 parts, fritillaria thunbergii 50-150 parts, caulis bambusae in taenian 50-150 parts, airpotato yam 20-80 parts,
Root bark of white mulberry 20-80 parts.
Preferably, the Chinese medicine composition is prepared from by the Chinese medicine material medicine of following weight proportion, blackberry lily 180-220
Part, subprostrate sophora 130-170 parts, Lasiosphaera fenzlii 130-170 parts, Chinese olive 80-120 parts, Oroxylum indicum 80-120 parts, fritillaria thunbergii 80-120 parts,
Caulis bambusae in taenian 80-120 parts, airpotato yam 30-70 parts, root bark of white mulberry 30-70 parts.
It is furthermore preferred that the Chinese medicine composition is prepared from by the Chinese medicine material medicine of following weight proportion, 200 parts of blackberry lily,
150 parts of subprostrate sophora, 150 parts of Lasiosphaera fenzlii, 100 parts of Chinese olive, 100 parts of Oroxylum indicum, 100 parts of fritillaria thunbergii, 100 parts of caulis bambusae in taenian, 50 parts of airpotato yam,
50 parts of the root bark of white mulberry.
The Chinese medicine composition of preventing and treating livestock and poultry cough and asthma of the present invention, is powder, capsule, oral liquid, granule, pill
Or tablet.
Present invention also offers the preparation method of described Chinese medicine composition, step is as follows：
1) blackberry lily, subprostrate sophora, Lasiosphaera fenzlii, Chinese olive, Oroxylum indicum, fritillaria thunbergii, caulis bambusae in taenian, airpotato yam, the root bark of white mulberry 9 of recipe quantity are weighed
Taste medicinal material adds 8-12 times to measure decocting to boil 1-3 times, each 1-3 hours, merges decoction liquor, filtration, stands overnight, leaching supernatant,
Relative density 1.21-1.27 (50 DEG C) is concentrated under reduced pressure into, dry cream is dried to.
2) dry cream is ground into fine powder, crosses 100 mesh sieves, add appropriate amount of auxiliary materials, mixed, prepare capsule, powder, granule
Or tablet.
Present invention also offers described Chinese medicine composition in the medicine for treating or preventing livestock and poultry cough and asthma is prepared
Using.
Medicine is constituted and analyzed：
In Chinese medicine composition of the invention, blackberry lily is monarch drug in a prescription, and subprostrate sophora, Lasiosphaera fenzlii are ministerial drug, and remaining is adjutant.
Blackberry lily：Hardship, trembles with fear.Return lung is passed through.Function with cure mainly：It is clearing heat and detoxicating, dissolving phlegm, relieving sore-throat.For heat toxin convulsive seizure due to phlegm-fire pent-up, throat
Swell and ache, accumulation and obstruction of sputum, cough and asthma.It is heat-clearing and detoxifying herb, with removing toxic substances relieving sore-throat, clearing heat and eliminating phlegm, radiating disappears the effect of knot.It is main
It is used for the diseases such as throat lung carbuncle, productive cough asthma.《Detailed outline》：" blackberry lily, energy fall fire, therefore ancient prescription controls larynx numbness pharyngalgia for key medicine.Grandson true man
《Prescriptions worth thousand gold》Controlling larynx numbness has black Wooden-fan cream.Zhang Zhongjing《The deficient beautiful letter of gold》Side controls cough and dyspnea, and water bird sound is made in larynx, there is blackberry lily Chinese ephedra
Soup.Preventing and curing malaria mother biejiajian pills, was also burnt with crow fan again, is all taken it and is dropped cloudy mutually fire of fainting.Then scattered the swelling of blood disappears fire drop, and phlegm knot is certainly
Solution, abdominal mass is removed certainly.
Subprostrate sophora：Hardship, trembles with fear；It is poisonous.Attach to the lung and stomach meridians.Function with cure mainly：It is clearing heat and detoxicating, relieving sore-throat of subsiding a swelling.Accumulate for fiery poison
Knot, tonsillitis and larynx numbness, abscess of throat, gingivitis, aphthae.《Bencao Jingshu》：" subprostrate sophora, it is sweet so and poison, tremble with fear so removing
Heat, all malicious Bi Rebixin obtain poor gas, the taste of sweetness and bitterness, then all poison are self solved, therefore are the medicine-feeding of removing toxic substances heat-clearing.All pains must because in
Heat, malicious antipyretic scattered, then from only, sore swells disappear pain certainly.Acute febrile, is that blood-head pole is sent out, therefore must be generated heat, and then hair cough is smoked on hot gas.It is all
Worm also damp and hotization, therefore master is known, and obtain special effect more.”
Lasiosphaera fenzlii：It is pungent, put down.Return lung is passed through.Function with cure mainly：Removing heat from the lung and relieving sorethroat, hemostasis.For the strongly fragrant lung pharyngalgia of wind-heat, sound is mute, coughs
Cough；Control nosebleed epistaxis, traumatic bleeding outward.Lasiosphaera fenzlii is a kind of medicinal fungi for detoxifying, subsiding a swelling, even more a kind of hemostasis good medicine.Lasiosphaera fenzlii
Containing various amino acid, 8 kinds of amino acid contents needed by human are higher, particularly lysine, methionine content it is very high, also contain
There are gemmatein, inorganic salts and trace element etc..
Chinese olive：It is bitter, pungent, temperature.Return liver, courage, stomach.Function with cure mainly：Soothing the liver relieving stagnant Qi, disperse accumulationsization is stagnant.For distending pain in the chest and hypochondrium,
Hernia pain, newborn addiction, acute mastitis, stagnation of QI due to dyspepsia, abdominal distention.《Collected statements on the herbal foundation》：" lunar, Foot yangming Channel of starting with." for treating
Abscess of throat, polydipsia of coughing.
Oroxylum indicum：It is bitter, sweet, it is cool.Return lung, liver, stomach.Function with cure mainly：Cheongju lung relieving sore-throats, soothing liver and harmonizing stomach.Coughed for lung heat
Cough, larynx numbness, sound is mute, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.Hepatitis is also used for, difficulty and pain in micturition, abscess of throat, eczema, ulcerative carbuncle is festered.Cure mainly and be to cough
The diseases such as the infection of the upper respiratory tract, acute bronchitis, chronic pharyngitis, the pneumonia later stage of primary symptom.Modern medicine study shows, Oroxylum indicum
With multiple pharmacological effects such as analgesia, anti-inflammatory, antibacterial, anti-oxidant, suppression virus and tumour growths.
Fritillaria thunbergii：Hardship, trembles with fear.Return lung, the heart channel of Hang-Shaoyin.Function with cure mainly：Clearing heat, eliminating phlegm, relieving cough, detoxicating and resolving a mass disappears carbuncle.For wind-heat
Cough, phlegm-fire cough, lung carbuncle, acute mastitis, scrofula, sore.《Detailed outline is picked up any lost article from the road》：" the sharp phlegm of removing toxic substances opens facilitaing lung gas, all lung man folder wind fire
The person that has phlegm preferably this.”
Caulis bambusae in taenian：It is sweet, it is slightly cold.Return lung, stomach, the heart, gallbladder channel.Function with cure mainly：Clearing heat and eliminating phlegm, relieving restlessness, preventing or arresting vomiting.Coughed for phlegm heat
Cough, courage fire holds phlegm under the arm, palpitation with fear is not peaceful, vexed insomnia, middle wind phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pernicious vomiting, fetal irritability.
《Compendium of Materia Medica》：Typhoid fever labor is answered, the hot epilepsy of children, married woman's movement of the foetus.《Haigoushen》：Only consumptive lung disease spitting blood, nosebleed epistaxis, control five hemorrhoid.《Book on Chinese herbal medicine
Just》：Consumptive lung disease saliva phlegm, hematuria are controlled, married woman's blood-head collapses pouring, movement of the foetus, and children's wind-heat Dian Epilepsy, and mental disorder is breathed with cough, and small hydro-thermal is puckery.
Airpotato yam：Hardship, it is pungent, it is salty, it is cool in nature, it is slightly poisonous.Indication：Dissipating bind disappears goitre, clearing heat and detoxicating, cooling blood and hemostasis.For
Goiter and tumor, sore swollen toxin, abscess of throat is spitted blood, bleeding from five sense organs or subcutaneous tissue, venomous snake bite, various tumours.Degrading the channel, sharp joint.Sore subcutaneous ulcer is cured mainly to swell
Poison, tonsillitis, sphagitis, snake, dog bite.《Kaibao Bencao》：Master is all to dislike swollen sore fistula, and larynx numbness, snake dog stings poison, takes root and grind clothes
It, also containing also applying.
The root bark of white mulberry：It is sweet, tremble with fear.Return lung is passed through.Function with cure mainly：Removing heat from lung and relieving asthma, inducing diuresis for removing edema.For dyspnea and cough due to lung-heat, oedema is swollen
Full oliguria, appearance skin edema.With purging the lung of pathogenic fire heat, relieving asthma as speciality, energy inducing diuresis to remove edema, regulating fluid apssage, and the respectful drop lung qi of energy, preferably use
In oedema real example, difficult urination, the edema of the face, or water drink stop lung, and turgor breathes heavily the disease such as anxious.There are certain hypotensive, diuresis and town
Quiet effect.
The invention has the advantages that：
Chinese medicine composition of the invention have selected the medicine mutually made with mutual reinforcement between, can produce synergy, each other may be used
Promote curative effect, instant effect, without any toxic and side effect, the recurrence after healing can be avoided, and the Chinese medicine composition efficacy stability, not because of the time
Long and impact effect.
Specific embodiment
Following examples are used to illustrate the present invention, but are not limited to the scope of the present invention.
Embodiment 1
A kind of Chinese medicine composition for preventing and treating livestock and poultry cough and asthma, it is made up of the Chinese medicine material of following weight portion：Blackberry lily 200g,
Subprostrate sophora 150g, Lasiosphaera fenzlii 150g, Chinese olive 100g, Oroxylum indicum 100g, fritillaria thunbergii 100g, caulis bambusae in taenian 100g, airpotato yam 50g, the root bark of white mulberry
50g.Its specific preparation method is as follows：
1) blackberry lily, subprostrate sophora, Lasiosphaera fenzlii, Chinese olive, Oroxylum indicum, fritillaria thunbergii, caulis bambusae in taenian, airpotato yam, the root bark of white mulberry 9 of recipe quantity are weighed
Taste medicinal material adds the decocting of 10 times of amounts to boil 3 times, 2 hours every time, merges decoction liquor, filtration, stands overnight, leaching supernatant, depressurizes dense
Relative density 1.21-1.27 (50 DEG C) is reduced to, dry cream is dried to.
2) dry cream is ground into fine powder, crosses 100 mesh sieves, add appropriate amount of auxiliary materials, mixed, prepare capsule, powder, granule
Or tablet.
Embodiment 2
A kind of Chinese medicine composition for preventing and treating livestock and poultry cough and asthma, it is made up of the Chinese medicine material of following weight portion：Blackberry lily 250g,
Subprostrate sophora 150g, Lasiosphaera fenzlii 120g, Chinese olive 120g, Oroxylum indicum 80g, fritillaria thunbergii 80g, caulis bambusae in taenian 80g, airpotato yam 60g, root bark of white mulberry 60g.
Its specific preparation method is as follows：
1) blackberry lily, subprostrate sophora, Lasiosphaera fenzlii, Chinese olive, Oroxylum indicum, fritillaria thunbergii, caulis bambusae in taenian, airpotato yam, the root bark of white mulberry 9 of recipe quantity are weighed
Taste medicinal material adds the decocting of 10 times of amounts to boil 3 times, 2 hours every time, merges decoction liquor, filtration, stands overnight, leaching supernatant, depressurizes dense
Relative density 1.21-1.27 (50 DEG C) is reduced to, dry cream is dried to.
2) dry cream is ground into fine powder, crosses 100 mesh sieves, add appropriate amount of auxiliary materials, mixed, prepare capsule, powder, granule
Or tablet.
Embodiment 3
A kind of Chinese medicine composition for preventing and treating livestock and poultry cough and asthma, it is made up of the Chinese medicine material of following weight portion：Blackberry lily 220g,
Subprostrate sophora 200g, Lasiosphaera fenzlii 100g, Chinese olive 80g, Oroxylum indicum 100g, fritillaria thunbergii 120g, caulis bambusae in taenian 80g, airpotato yam 70g, the root bark of white mulberry
30g.Its specific preparation method is as follows：
Weigh blackberry lily, subprostrate sophora, Lasiosphaera fenzlii, Chinese olive, Oroxylum indicum, fritillaria thunbergii, caulis bambusae in taenian, airpotato yam, the taste of the root bark of white mulberry 9 of recipe quantity
Medicinal material adds the decocting of 10 times of amounts to boil 3 times, 2 hours every time, merges decoction liquor, filtration, stands overnight, leaching supernatant, is concentrated under reduced pressure
Make alcohol content to 60%~70% to the clear cream of relative density 1.05-1.15 (50 DEG C), plus ethanol, stand 24~48 hours, mistake
Filter, filtrate recycling ethanol to without alcohol taste, plus 1-3 ‰ preservative, add water to 1000ml, be made oral liquid.
Embodiment 4
A kind of Chinese medicine composition for preventing and treating livestock and poultry cough and asthma, it is made up of the Chinese medicine material of following weight portion：Blackberry lily 200g,
Subprostrate sophora 150g, Lasiosphaera fenzlii 150g, Chinese olive 150g, Oroxylum indicum 100g, fritillaria thunbergii 100g, caulis bambusae in taenian 50g, airpotato yam 50g, the root bark of white mulberry
50g。
The flavour of a drug of above-mentioned recipe quantity are weighed, be dry, pulverize, cross 100 mesh sieves, be made powder.
Test example 1
To the therapeutic effect of pig cough illness
Clinical trial animal, in the DLY tri-crossbreeding 300 of 40kg-50kg, is faced from 100-120 ages in days, body weight
Bed symptom occurs breathing for pig, coughs, generates heat, loses the appetite or without appetite.The isolation of ill pig is individually raised, feeding full price is raised
Material, and it is randomly divided into 6 groups, every group 50,6 groups of feeding environments are identical, and experimental period is carried out 7 days altogether；Blank control group is not
Any treatment is done, drug control group is used according to an instruction treatment with institute's control drug " datura flower asthma relieving powder "；1 group is tested to implement
1 group of example, tests 2 groups for embodiment 1 lacks monarch drug in a prescription group, tests 3 groups for embodiment 1 lacks ministerial drug group, and 4 groups of experiment is 2 groups of embodiment, day
Dose is：Per 100g present composition spices 1kg feedings, 2 times a day.Treatment disease is reached by gastrointestinal absorption after oral
The purpose of disease.
Efficacy assessment standard：
Recovery from illness：Through treatment, clinical symptoms are wholly absent, and spirit, appetite recover normal
Effectively：Through treatment, clinical symptom remission, spirit, appetite are gradually recovered.
It is invalid：Through treatment, without alleviation, spirit, appetite are without improvement, or even death for clinical symptoms.
The present invention of table 1 is contrasted with the situation of other medicines treatment porcine respiratory disease
| Group | Number of cases | Recovery from illness | Effectively | It is invalid | Efficient % |
| Blank control group | 50 | 0 | 6 | 44 | 12 |
| Datura flower asthma relieving powder group | 50 | 41 | 4 | 5 | 90 |
| Test 1 group | 50 | 41 | 6 | 3 | 94 |
| Test 2 groups | 50 | 5 | 5 | 40 | 20 |
| Test 3 groups | 50 | 26 | 5 | 19 | 62 |
| Test 4 groups | 50 | 40 | 5 | 5 | 90 |
Conclusion：The effective percentage of blank control group is 12%, and the effective percentage of datura flower asthma relieving group is 90%, 1 group of experiment it is effective
Rate is 94%, and the effective percentage of 2 groups of experiment is 20%, and the effective percentage of 3 groups of experiment is 62%, and the effective percentage of 4 groups of experiment is 90%.Examination
Test result to show, the Chinese medicine composition reasonable recipe in the present invention, the cough illness effect is significant for treating pig.
Test example 2
To the therapeutic effect of chicken cough illness
From the 21 age in days chicken 600 of Beijing chicken house, clinical symptoms are decreased obviously for feed intake clinical trial animal, essence
Refreshing depressed, unilateral or bilateral nasal sinus, eyelid swelled, cough, sneeze, constantly getting rid of head, have difficulty in breathing.The isolation of ill chicken is independent
Raise, feed complete feed, and be randomly divided into 6 groups, every group 100,6 groups of feeding environments are identical, and experimental period carries out 7 altogether
My god；Blank control group is left intact, and drug control group is made with institute's control drug " Maxingshigan oral liquid " by its specification
With treatment；1 group is tested for 1 group of embodiment, 2 groups is tested for embodiment 1 lacks monarch drug in a prescription group, 3 groups is tested for embodiment 1 lacks ministerial drug group,
4 groups are tested for 2 groups of embodiment, day dose be：It is daily 1-2 times per 100g present composition spices 1kg feedings；After oral
The purpose for the treatment of disease is reached by gastrointestinal absorption.
Efficacy assessment standard：
Cure：Spirit, appetite, breathing recover normal, and tracheae does not have mucus, moistening, and lungs, Pathological cut open inspection are without notable
Histopathologic change, is judged to recovery from illness, and recovery from illness chicken number accounts for this group of percentage of chicken number for cure rate.
At the end of have symptom：Clinical symptoms do not improve even exacerbation.
The present invention of table 2 is contrasted with the situation of other medicines treatment chicken respiratory tract disease
Conclusion：The cure rate of blank control group is 0, and the cure rate of datura flower asthma relieving group is 86%, and the cure rate of 1 group of experiment is
91%, the cure rate of 2 groups of experiment is 10%, and the cure rate of 3 groups of experiment is 71%, and the cure rate of 4 groups of experiment is 89%.Experiment knot
Fruit shows that the Chinese medicine composition reasonable recipe in the present invention, the cough illness effect is significant for treating chicken is oral with numb apricot stone glycosides
Liquid group compares indifference in terms of cure rate.
Test example 3
Prevention to chicken cough illness
Clinical trial animal is randomly divided into 5 groups, every group 200,5 groups from the 21 age in days chicken 1000 of Beijing chicken house
Feeding environment is identical, and complete feed is fed in isolation, and experimental period is carried out 7 days altogether；Blank control group is left intact, real
1 group is tested for 1 group of embodiment, 2 groups is tested for embodiment 1 lacks monarch drug in a prescription group, 3 groups is tested for embodiment 1 lacks ministerial drug group, 4 groups of experiment is
2 groups of embodiment, day dose be：It is daily 1-2 times per 10g present composition spices 1kg feedings；Pass through intestines and stomach after oral
Absorption reaches the purpose for the treatment of disease.
Preventive effect of the Chinese medicine composition of the present invention of table 3 to chicken cough illness
| Group | Total (only) | Morbidity number (only) | Do not fall ill number (only) | Effective prevention rate (%) |
| Blank control group | 200 | 85 | 115 | 57.5 |
| Test 1 group | 200 | 21 | 179 | 89.5 |
| Test 2 groups | 200 | 72 | 128 | 64 |
| Test 3 groups | 200 | 35 | 165 | 82.5 |
| Test 4 groups | 200 | 23 | 177 | 88.5 |
Conclusion：Effective prevention rate of blank control group is 57.5%, and effective prevention rate of 1 group of experiment is 89.5%, experiment 2
Effective prevention rate of group is 64%, and effective prevention rate of 3 groups of experiment is 82.5%, and effective prevention rate of 4 groups of experiment is 88.5%,
Result of the test shows that the Chinese medicine composition reasonable recipe in the present invention has preferable preventive effect to the cough illness of chicken.
The present invention is found surprisingly that the collocation of each component of the present invention has synergistic function.
Although the present invention is described in detail above to have used general explanation and specific embodiment, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements, belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (6)
1. it is a kind of prevent and treat livestock and poultry cough and asthma Chinese medicine composition, it is characterised in that：The Chinese medicine composition is by following weight proportion
Chinese medicine material medicine is prepared from, blackberry lily 150-250 parts, subprostrate sophora 100-200 parts, Lasiosphaera fenzlii 100-200 parts, Chinese olive 50-150 parts,
Oroxylum indicum 50-150 parts, fritillaria thunbergii 50-150 parts, caulis bambusae in taenian 50-150 parts, airpotato yam 20-80 parts, root bark of white mulberry 20-80 parts.
2. Chinese medicine composition as claimed in claim 1, it is characterised in that：The Chinese medicine composition is by following raw material group
Divide and be prepared from, blackberry lily 180-220 parts, subprostrate sophora 130-170 parts, Lasiosphaera fenzlii 130-170 parts, Chinese olive 80-120 parts, Oroxylum indicum 80-
120 parts, fritillaria thunbergii 80-120 parts, caulis bambusae in taenian 80-120 parts, airpotato yam 30-70 parts, root bark of white mulberry 30-70 parts.
3. Chinese medicine composition as claimed in claim 1, it is characterised in that：The Chinese medicine composition is by following weight proportion
Medicine bulk drug is prepared from, 200 parts of blackberry lily, 150 parts of subprostrate sophora, 150 parts of Lasiosphaera fenzlii, 100 parts of Chinese olive, 100 parts of Oroxylum indicum, fritillaria thunbergii
100 parts, 100 parts of caulis bambusae in taenian, 50 parts of airpotato yam, 50 parts of the root bark of white mulberry.
4. composition according to claim 1, it is characterised in that：The composition is any pharmaceutically useful formulation.
5. composition according to claim 4, it is characterised in that：The formulation is selected from：Tablet, capsule, granule, ball
Agent, powder, paste, sublimed preparation, pulvis, solution, injection, suppository, spray, drops, patch.
6. the preparation method of the composition described in claim 1, it is characterised in that：The step of preparation method, is as follows：Blackberry lily,
Subprostrate sophora, Lasiosphaera fenzlii, Chinese olive, Oroxylum indicum, fritillaria thunbergii, caulis bambusae in taenian, airpotato yam, the taste medicinal material of the root bark of white mulberry 9 add 8-12 times to measure decocting to boil 1-3
It is secondary, it is each 1-3 hours, merge decoction liquor, filtration stands overnight, leaching supernatant, is concentrated under reduced pressure, and is dried to dry cream.By dry cream
Fine powder is ground into, 100 mesh sieves are crossed, appropriate amount of auxiliary materials is added, mixed, prepare capsule, powder, granule or tablet.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102327457A (en) * | 2011-09-16 | 2012-01-25 | 重庆市南川区瑞丰农业开发有限责任公司 | Chinese herbal medicine for treating yin deficiency lung heat and wind phlegm pharyngalgia |
| CN103656397A (en) * | 2012-09-18 | 2014-03-26 | 青岛医防消毒专业技术中心 | Compound medicine for treating chronic pharyngitis |
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2016
- 2016-12-29 CN CN201611241782.3A patent/CN106729085A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102327457A (en) * | 2011-09-16 | 2012-01-25 | 重庆市南川区瑞丰农业开发有限责任公司 | Chinese herbal medicine for treating yin deficiency lung heat and wind phlegm pharyngalgia |
| CN103656397A (en) * | 2012-09-18 | 2014-03-26 | 青岛医防消毒专业技术中心 | Compound medicine for treating chronic pharyngitis |
Non-Patent Citations (1)
| Title |
|---|
| 穆春雷等: "麻杏石甘定喘汤治疗鸡咳喘症", 《中兽医医药杂志》 * |
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Application publication date: 20170531 |