CN106723016A - 一种金花茶含片的制作方法 - Google Patents
一种金花茶含片的制作方法 Download PDFInfo
- Publication number
- CN106723016A CN106723016A CN201611036469.6A CN201611036469A CN106723016A CN 106723016 A CN106723016 A CN 106723016A CN 201611036469 A CN201611036469 A CN 201611036469A CN 106723016 A CN106723016 A CN 106723016A
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- weight
- extract solution
- weight portion
- buccal tablets
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Classifications
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Abstract
本发明公开了一种金花茶含片的制作方法，所述金花茶含片的制作方法包括以下步骤：1)将牛蒡、罗汉果、甜菜菊、芹菜、酸浆草、竹蔗、茅根、胖大海、去离子水采用超声波进行水提和醇提得到第一提取液和第二提取液；2)将金花茶花朵、金花茶叶冷冻干燥粉碎，加入冰醋酸、乙醇和去离子水，放置高压脉冲波电场中20‑30分钟后，采用超声波提取得到所述第三提取液；3)将第一提取液、第二提取液和第三提取液合并减压喷雾干燥后得到粉末，按重量比1∶1∶5加入硬脂酸镁、羟丙甲纤维素、环糊精混合进行压片，压片后，得到所述含片；本发明制成的金花茶含片具有显著的抗氧化、提高身体机能、调节血糖、提高身体免疫力，并且适合各种人群使用。
Description
技术领域
本发明涉及金花茶保健品技术领域，具体涉及一种金花茶含片的制作方法。
背景技术
据中国疾病预防控制中心营养与食品安全所、广西壮族自治区疾病预防控制中心、广西壮族自治区卫生监督检验中心、北京疾病预防控制中心中心营养与食品安全所、广西壮族自治区分析测试研究中心、广西中医学院、广西农学院实验中心等权威机构检验表明：金花茶属无毒级、含有400多种营养物质、无毒副作用。富含茶多糖、茶多酚、总皂甙、总黄酮、茶色素、咖啡因、蛋白质、维生素B1、B2、维生素C、维生素E、叶酸、脂肪酸、B-胡萝卜素等多种天然营养成份；金花茶含有茶氨酸、苏氨酸等几十种氨基酸，以及富含有多种对人体具有重要保健作用的天然有机锗(Ge)、硒(Se)、钼(Mo)、锌(Zn)、钒(V)等微量元素，和钾(K)、钙(Ca)、镁(Mg)等宏量元素。目前的金花茶多为纯花朵茶，味道单一，制作工艺复杂，或是制成口服液等。
发明内容
本发明的一个目的提供一种金花茶含片的制作方法。
本发明提供的技术方案为：
一种金花茶含片的制作方法，所述金花茶含片的制作方法包括以下步骤：
1)将70重量份牛蒡、150重量份罗汉果、30重量份甜菜菊、40重量份芹菜、100重量份酸浆草、45重量份竹蔗、30重量份茅根、100重量份胖大海、1000重量份去离子水采用高速搅拌机搅拌1-2小时后，加入10重量份纤维素酶和15重量份果胶酶，调节pH值至4-5，温度为45℃，静置1-2小时后，超声波提取0.5-1小时后，进行灭酶，过滤得到第一提取液和滤渣，往滤渣中加入500重量份质量分数70％的乙醇回流提取1-2次，过滤得到第二提取液；
2)将800份重量份金花茶花朵、150份重量份金花茶叶冷冻干燥至水分含量小于10％，机械粉碎后过100目筛子，加入50份冰醋酸、700份乙醇和500份去离子水，放置高压脉冲波电场中20-30分钟后，采用超声波提取1-2小时，过滤、通过减压浓缩装置回收乙醇和冰醋酸后得到所述第三提取液；
3)将第一提取液、第二提取液和第三提取液合并减压喷雾干燥后得到粉末，按重量比1∶1∶5加入硬脂酸镁、羟丙甲纤维素、环糊精混合后高速搅拌均匀最后进行压片，压片后，进行冷冻干燥至含片的水分含量小于8％，得到所述含片；其中减压喷雾干燥能降低干燥温度，减少有效物质的氧化和损失；
其中硬脂酸镁、羟丙甲纤维素、环糊精的总重为粉末的10-30倍。
优选的是，步骤2)中还包括在放置高压脉冲波电场前，加入10重量份纤维素酶，静置30分钟。
优选的是，步骤3)中加入所述粉末重量1％的螺旋藻粉与硬脂酸镁、羟丙甲纤维素、环糊精混合后高速搅拌均匀最后进行压片，添加螺旋藻粉能使含片具有润肠通便调节肠胃的作用。
优选的是，步骤3)中加入所述粉末重量1-5％的珍珠粉与硬脂酸镁、羟丙甲纤维素、环糊精混合后高速搅拌均匀最后进行压片，珍珠粉不仅能作为附型剂，还对肠胃粘膜具有修复作用。
优选的是，步骤1)中所述超声波的工作频率为50-100赫兹，步骤2)中所述超声波的工作频率为50-100赫兹，在超声波的作用下，有效物质易于析出和提取。
优选的是，步骤3)中所述减压喷雾干燥，其中压力为0.2个大气压，干燥的温度为50-70℃；所述高压脉冲电场，电压为30-40kv，脉冲数为20。
本发明的有益效果如下：
1)本发明制作方法的制成的金花茶含片不仅具有金花茶的抗氧化、提高身体机能、调节血糖的作用，其中牛蒡、芹菜、苦瓜具有显著降血压血脂的作用，竹蔗和茅根具有利尿键肾的作用，采用罗汉果、甜菜菊调节金花茶含片的甜味和掩盖其他药物的苦涩味道，并且适合糖尿病或是高血糖患者使用，添加的胖大海和酸浆草对于对于牙龈肿痛、口腔溃疡及咽炎有显著的效果；本发明方法制备的金花茶、竹蔗、螺旋藻和珍珠粉协同作用能调节内分泌失调和稳定情绪，减少失眠多梦，有效治疗黄褐斑和痤疮。
2)本发明的制作方法采用酶解后通过超声波水提取和醇提取牛蒡、罗汉果、甜菜菊、芹菜、酸浆草、竹蔗、茅根、胖大海中的有效成分，二次提取提高有效成分的提取率，金花茶花朵、金花茶叶采用冷冻干燥能保留金花茶花朵、金花茶叶中茶多酚、茶多糖及总黄酮和多种微量元素，经过酶解能将植物细胞的纤维素膜酶解有利于有效物质提取，再经过高压脉冲电场有利于植物细胞的破裂有效物质的析出，总体提高的金花茶和茶叶中的有效物质的提取率，提高金花茶和茶叶的利用率，使得本发明制成的金花茶含片具有显著的抗氧化、提高身体机能、调节血糖、提高身体免疫力，并且适合各种人群使用。
具体实施方式
下面结合具体实施例对本发明做进一步的详细说明，以令本领域技术人员参照说明书文字能够据以实施。
实施例1：
一种金花茶含片的制作方法包括以下步骤：
1)将70重量份牛蒡、150重量份罗汉果、30重量份甜菜菊、40重量份芹菜、100重量份酸浆草、45重量份竹蔗、30重量份茅根、100重量份胖大海、1000重量份去离子水采用高速搅拌机搅拌1小时后，加入10重量份纤维素酶和15重量份果胶酶，调节pH值至4，温度为45℃，静置1小时后，超声波提取0.5小时后，进行灭酶，过滤得到第一提取液和滤渣，往滤渣中加入500重量份质量分数70％的乙醇回流提取1次，过滤得到第二提取液；
2)将800份重量份金花茶花朵、150份重量份金花茶叶冷冻干燥至水分含量小于10％，机械粉碎后过100目筛子，加入50份冰醋酸、700份乙醇和500份去离子水，放置高压脉冲波电场中20分钟后，采用超声波提取1小时，过滤、通过减压浓缩装置回收乙醇和冰醋酸后得到所述第三提取液；
3)将第一提取液、第二提取液和第三提取液合并减压喷雾干燥后得到粉末，按重量比1∶1∶5加入硬脂酸镁、羟丙甲纤维素、环糊精混合后高速搅拌均匀最后进行压片，每片1-2克重，压片后，进行冷冻干燥至含片的水分含量小于8％，得到所述含片；
其中硬脂酸镁、羟丙甲纤维素、环糊精的总重为粉末的10倍。
实施例2
一种金花茶含片的制作方法，所述金花茶含片的制作方法包括以下步骤：
1)将70重量份牛蒡、150重量份罗汉果、30重量份甜菜菊、40重量份芹菜、100重量份酸浆草、45重量份竹蔗、30重量份茅根、100重量份胖大海、1000重量份去离子水采用高速搅拌机搅拌2小时后，加入10重量份纤维素酶和15重量份果胶酶，调节pH值至5，温度为45℃，静置2小时后，超声波提取1小时后，进行灭酶，过滤得到第一提取液和滤渣，往滤渣中加入500重量份质量分数70％的乙醇回流提取1-2次，过滤得到第二提取液；
2)将800份重量份金花茶花朵、150份重量份金花茶叶冷冻干燥至水分含量小于10％，机械粉碎后过100目筛子，加入50份冰醋酸、700份乙醇、500份去离子水及10重量份纤维素酶，静置30分钟后，放置高压脉冲波电场中30分钟后，采用超声波提取2小时，过滤、通过减压浓缩装置回收乙醇和冰醋酸后得到所述第三提取液；
3)将第一提取液、第二提取液和第三提取液合并减压喷雾干燥后得到粉末，按重量比1∶1∶5加入硬脂酸镁、羟丙甲纤维素、环糊精混合后高速搅拌均匀最后进行压片，压片后，进行冷冻干燥至含片的水分含量小于8％，得到所述含片；
其中硬脂酸镁、羟丙甲纤维素、环糊精的总重为粉末的10-30倍。
实施例3
一种金花茶含片的制作方法包括以下步骤：
1)将70重量份牛蒡、150重量份罗汉果、30重量份甜菜菊、40重量份芹菜、100重量份酸浆草、45重量份竹蔗、30重量份茅根、100重量份胖大海、1000重量份去离子水采用高速搅拌机搅拌2小时后，加入10重量份纤维素酶和15重量份果胶酶，调节pH值至5，温度为45℃，静置2小时后，超声波提取1小时后，进行灭酶，过滤得到第一提取液和滤渣，往滤渣中加入500重量份质量分数70％的乙醇回流提取1-2次，过滤得到第二提取液；
2)将800份重量份金花茶花朵、150份重量份金花茶叶冷冻干燥至水分含量小于10％，机械粉碎后过100目筛子，加入50份冰醋酸、700份乙醇和500份去离子水，放置高压脉冲波电场中25分钟后，采用超声波提取1.5小时，过滤、通过减压浓缩装置回收乙醇和冰醋酸后得到所述第三提取液；
3)将第一提取液、第二提取液和第三提取液合并减压喷雾干燥后得到粉末，加入所述粉末重量1％的螺旋藻粉，再按重量比1∶1∶5加入硬脂酸镁、羟丙甲纤维素、环糊精混合后高速搅拌均匀最后进行压片，压片后，进行冷冻干燥至含片的水分含量小于8％，得到所述含片；
其中硬脂酸镁、羟丙甲纤维素、环糊精的总重为粉末的20倍。
实施例4
一种金花茶含片的制作方法包括以下步骤：
1)将70重量份牛蒡、150重量份罗汉果、30重量份甜菜菊、40重量份芹菜、100重量份酸浆草、45重量份竹蔗、30重量份茅根、100重量份胖大海、1000重量份去离子水采用高速搅拌机搅拌1.5小时后，加入10重量份纤维素酶和15重量份果胶酶，调节pH值至4，温度为45℃，静置2小时后，超声波提取0.5小时后，进行灭酶，过滤得到第一提取液和滤渣，往滤渣中加入500重量份质量分数70％的乙醇回流提取1次，过滤得到第二提取液；所述超声波的工作频率为80赫兹；
2)将800份重量份金花茶花朵、150份重量份金花茶叶冷冻干燥至水分含量小于10％，机械粉碎后过100目筛子，加入50份冰醋酸、700份乙醇、500份去离子水和10重量份纤维素酶，静置30分钟后，放置高压脉冲波电场中25分钟，再采用超声波提取2小时，过滤、通过减压浓缩装置回收乙醇和冰醋酸后得到所述第三提取液；所述超声波的工作频率为50-100赫兹；
3)将第一提取液、第二提取液和第三提取液合并减压喷雾干燥后得到粉末，加入所述粉末重量1％的螺旋藻粉和所述粉末重量5％的珍珠粉，再按重量比1∶1∶5加入硬脂酸镁、羟丙甲纤维素、环糊精混合后高速搅拌均匀最后进行压片，压片后，进行冷冻干燥至含片的水分含量小于8％，得到所述含片；
其中硬脂酸镁、羟丙甲纤维素、环糊精的总重为粉末的25倍；
所述减压喷雾干燥，其中压力为0.2个大气压，干燥的温度为60℃；所述高压脉冲电场，电压为30kv，脉冲数为20。
毒性试验：
对小鼠进行急性毒性测试，采用健康的大鼠喂食染毒，染毒后大鼠未见异常，观察期无死亡。
临床试验
本发明使用方法可吞服或口含，一天1-2片
黄某，女，40岁，经常口腔溃疡，高血脂，每天1片服用本发明1月后，血脂下降至正常值，服用过程中未见口腔溃疡，继续服用本发明2个月，血脂在正常值，无口腔溃疡，后续不服用本发明观察2个月，血脂平稳在正常值，并且无口腔溃疡。
李某，男，15岁，牙痛1个月，服用本发明每天2片，服用一天后牙痛明显减缓，一星期后，牙痛治愈。
廖某，男，60岁，高血糖高血压5年，服用本发明，每天2片，1个月后血糖血压有所下降，继续服用2个月后，血糖血压测试在正常值，不服用本发明继续观察半年，患者血糖血压均无升高，在正常值范围内。
林某，女，30岁，内分泌失调，常有失眠脸上黄褐斑痤疮明显，服用本发明，每天2片，1星期后痤疮渐渐消失，失眠现象有所缓解，服用1个月后黄褐斑渐渐消除，无失眠症状，痤疮完全治好，继续服用2个月后黄褐斑清除，停止服用继续观察3个月，黄褐斑痤疮都无复发，并且无失眠症状。
尽管本发明的实施方案已公开如上，但其并不仅仅限于说明书和实施方式中所列运用，它完全可以被适用于各种适合本发明的领域，对于熟悉本领域的人员而言，可容易地实现另外的修改，因此在不背离权利要求及等同范围所限定的一般概念下，本发明并不限于特定的细节和这里示出与描述的实施例。
Claims (6)
1.一种金花茶含片的制作方法，其特征在于，所述金花茶含片的制作方法包括以下步骤：
1)将70重量份牛蒡、150重量份罗汉果、30重量份甜菜菊、40重量份芹菜、100重量份酸浆草、45重量份竹蔗、30重量份茅根、100重量份胖大海、1000重量份去离子水采用高速搅拌机搅拌1-2小时后，加入10重量份纤维素酶和15重量份果胶酶，调节pH值至4-5，温度为45℃，静置1-2小时后，超声波提取0.5-1小时后，进行灭酶，过滤得到第一提取液和滤渣，往滤渣中加入500重量份质量分数70％的乙醇回流提取1-2次，过滤得到第二提取液；
2)将800份重量份金花茶花朵、150份重量份金花茶叶冷冻干燥至水分含量小于10％，机械粉碎后过100目筛子，加入50份冰醋酸、700份乙醇和500份去离子水，放置高压脉冲波电场中20-30分钟后，采用超声波提取1-2小时，过滤、通过减压浓缩装置回收乙醇和冰醋酸后得到所述第三提取液；
3)将第一提取液、第二提取液和第三提取液合并减压喷雾干燥后得到粉末，按重量比1∶1∶5加入硬脂酸镁、羟丙甲纤维素、环糊精混合后高速搅拌均匀最后进行压片，压片后，进行冷冻干燥至含片的水分含量小于8％，得到所述含片；
其中硬脂酸镁、羟丙甲纤维素、环糊精的总重为粉末的10-30倍。
2.如权利要求1所述的金花茶含片的制作方法，其特征在于，步骤2)中还包括在放置高压脉冲波电场前，加入10重量份纤维素酶，静置30分钟。
3.如权利要求1所述的金花茶含片的制作方法，其特征在于，步骤3)中加入所述粉末重量1％的螺旋藻粉与硬脂酸镁、羟丙甲纤维素、环糊精混合后高速搅拌均匀最后进行压片。
4.如权利要求1所述的金花茶含片的制作方法，其特征在于，步骤3)中加入所述粉末重量1-5％的珍珠粉与硬脂酸镁、羟丙甲纤维素、环糊精混合后高速搅拌均匀最后进行压片。
5.如权利要求1所述的金花茶含片的制作方法，其特征在于，步骤1)中所述超声波的工作频率为50-100赫兹，步骤2)中所述超声波的工作频率为50-100赫兹。
6.如权利要求1所述的金花茶含片的制作方法，其特征在于，步骤3)中所述减压喷雾干燥，其中压力为0.2个大气压，干燥的温度为50-70℃；所述高压脉冲电场，电压为30-40kv，脉冲数为20。
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| CN106072636A (zh) * | 2016-06-22 | 2016-11-09 | 广西防城金花茶国家级自然保护区管理处 | 以金花茶为原料的解酒含片及其生产方法 |
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