CN106072636A - 以金花茶为原料的解酒含片及其生产方法 - Google Patents
以金花茶为原料的解酒含片及其生产方法 Download PDFInfo
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- CN106072636A CN106072636A CN201610456333.4A CN201610456333A CN106072636A CN 106072636 A CN106072636 A CN 106072636A CN 201610456333 A CN201610456333 A CN 201610456333A CN 106072636 A CN106072636 A CN 106072636A
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- camellia nitidissima
- sobering
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- nitidissima chi
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Abstract
本发明公开了以金花茶为原料的解酒含片及其生产方法，该解酒含片有效成分的原料的重量份如下：金花茶叶或茶花15‑25份，葛根叶或花20‑40份，白茅根10‑20份，菊花15‑30份。本发明的解酒含片含有多种氨基酸、微量元素、植物蛋白、维生素等营养成分，具有消酒、清热解毒、镇静、清肺清脑、护肝护胆护胃的功效。其有效成分会在体内迅速分解代谢酒精，促进肝脏解毒、肾脏排泄的功能，起到醒酒、清脑、防醉的作用，同时具有活血化瘀、软化血管、增强血管血液流量、促进心脑血管血液循环、降低血糖血压血脂、对大脑供血不足及心脏心肌缺血有保护作用。
Description
技术领域
本发明涉及解酒保健品技术领域，具体是一种以金花茶为原料具有解酒功能的保健含片。
背景技术
中国是酒文化王国。自古以来，举凡年节吉日、婚丧嫁娶、庆生奠死、宴亲飨客、洗尘饯行等等，人们生活的方方面面、时时刻刻几乎都离不开酒。饮酒，也是如今人们日常生活的一项重要内容，随着我国市场经济的发展，商业活动日趋频繁，人们在日常应酬中免不了时常饮酒，由于大量饮酒造成的身体不适状况屡见不鲜，饮酒者的身体健康受到威胁。
酒精在体内的代谢过程，主要在肝脏中进行，少量酒精可在进入人体之后，马上随肺部呼吸或经汗腺排出体外，绝大部分酒精在肝脏中先与乙醇脱氢酶作用，生成乙醛，乙醛对人体有害，但它很快会在乙醛脱氢酶的作用下转化成乙酸。乙酸是酒精进入人体后产生的唯一有营养价值的物质，它可以提供人体需要的热量。酒精在人体内的代谢速率是有限度的，如果饮酒过量，酒精就会在体内器官，特别是在肝脏和大脑中积蓄，积蓄至一定程度即出现酒精中毒症状。
对于醉酒人们的传统做法是喝醋或者喝茶，但效果甚微，主要原因是茶叶中的咖啡碱，茶碱，可可碱等有兴奋心脏的作用，饮酒后喝茶会增加对心脏的刺激，喝醋不但不能解酒，而且对消化道黏膜还会产生损伤。临床上通常使用各类口服西药，不但药效不明显且会对患者产生一些副作用。
金花茶是一种古老的植物，极为罕见，分布极其狭窄，全世界90%的野生金花茶仅分布于中国广西壮族自治区防城港市十万大山的兰山支脉一带，生长于海拔700米以下，数量极少，是世界上稀有的珍贵植物。经检验表明，金花茶属无毒级、含有400多种营养物质、无毒副作用。富含茶多糖、茶多酚、总皂甙、总黄酮、茶色素、咖啡因、蛋白质、维生素B1、B2、维生素C、维生素E、叶酸、脂肪酸、B-胡萝卜素等多种天然营养成份；金花茶含有茶氨酸、苏氨酸等几十种氨基酸，以及富含有多种对人体具有重要保健作用的天然有机锗（Ge）、硒（Se）、钼（M）、锌（Zn）、钒（V）等微量元素，和钾（K）、钙（Ca）、镁（Mg）等宏量元素。民间又称金花茶为“神茶”，国外称之为神奇的东方魔茶，被誉为“植物界大熊猫”、“茶族皇后”。金花茶具有明显的降血糖和尿糖作用，能有效的改善糖尿病“三高”症状。金花茶在有效降低血糖、血压的同时，可有效降低血脂，改善因高血压而引起的各种不适应症状，降低血清中胆固醇和B-脂蛋白，促进胰岛素分泌、增强免疫力、调节血流量，防止动脉粥样硬化，抗菌消炎、清热解毒、通便利尿去湿，增进肝脏代谢、防癌抑制肿瘤生长等。此外，我们的研究表明，金花茶对于提高体内的乙醛脱氢酶具有显著的作用，因此将金花茶和其他具有提高乙醇脱氢酶活性的原料搭配，可以起到加快酒精分解，缓解酒后中毒症状的作用。
目前市场上的解酒含片种类繁多，功效单一不明显且含有较大比例的化学成分，带有一定的毒副作用，人们对绿色无副作用的健康解酒含片的需求越来越高。本发明利用金花茶特有的药用价值，结合其他中草药及辅料，制成一种解酒功效强，且具有清凉降火、生津解渴、减脂降压、健胃消食的作用。
发明内容
本发明的目的是开发一种以金花茶为原料的解酒含片，利用了金花茶提高体内乙醛脱氢酶的作用，加入一些常见的能够食用的植物叶或花，结合解酒中药的效力，克服了传统解酒保健品的缺陷，具有清脑提神、清凉降火、生津解渴、减脂降压、健胃消食的作用。
本发明是通过以下技术方案实现的：
以金花茶为原料的解酒含片，由有效成分和辅料制成，所述有效成分的原料的重量份如下：金花茶叶或茶花15-25份，葛根叶或花20-40份，白茅根10-20份，菊花15-30份。
以上所述的以金花茶为原料的解酒含片，所述的辅料的重量份数为：山药粉22份、糙米粉22份、甜味剂5-10份、黄原胶1.5份、卵磷脂1.1份、柠檬酸2.2份和硬脂酸镁1.9份。其中所述甜味剂为不含蔗糖的甜味剂，为果糖、甜蜜素、木糖醇或麦芽糖醇中的一种或一种以上。
其生产方法包括以下工艺步骤：
（1）按原料的重量份取金花茶叶或茶花、葛根叶或花、白茅根和菊花；洗净晾干，研磨粉碎，然后加入20-25倍重量的水，煎煮20-30分钟，过滤取滤液，再加入2-3倍无水乙醇，静置2-3小时，收集醇沉后的上清液，最后向上清液中加入山药粉和糙米粉；
（2）将步骤（1）中含有山药粉和糙米粉的上清液用真空浓缩至膏状，并进行造粒、干燥和整粒处理；
（3）将步骤（2）整粒后的颗粒中加入其它剩余辅料，均匀搅拌混合；最后进行造粒、压片、包装处理得成品。
本解酒含片各组分在传统中医学理论中的作用如下：
金花茶（拉丁学名：Camellia nitidissima C. W. Chi）：金花茶在有效降低血糖、血压的同时，可有效降低血脂，改善因高血压而引起的各种不适应症状，降低血清中胆固醇和B-脂蛋白，促进胰岛素分泌、增强免疫力、调节血流量，防止动脉粥样硬化，抗菌消炎、清热解毒、通便利尿去湿，增进肝脏代谢、防癌抑制肿瘤生长等。金花茶中的总黄酮含量4400mg/kg, 黄酮类化合物具有降血压、降血脂、防止血栓形成、防治心脑血管疾病、增强免疫、降低血管脆性、改善心脑血管血液循环等作用，还可以抗菌及抗病毒，抗氧化、抗衰老，抗辐射，止咳、祛痰，以及抗肝脏毒。硒是人体红细胞中谷胱甘肽酶的成份，他有抗氧化，保护细胞膜，保护心血管的作用。中国科学家还发现，硒是治疗克山病和大骨节病的有效药物，此外，硒还有解毒功能，降低黄曲B1的毒性，对某些化学致癌物质有减毒作用，还能减轻毒素对肝细胞的损害。锗可降低癌细胞的生物电位，改变其生理状态，抑制癌细胞的增值生长，还可诱发人体内抗癌物质的干扰素，能将巨噬细胞诱发变为抗癌细胞，故有人用锗治疗癌症，另外锗对血管硬化，脑血栓，脑出血，肾肝病，胃病，糖尿病，关节炎，慢性神经痛也有明显的疗效。金花茶花的作用，能够收敛止血，主便血；月经过多，对妇女特别有好处。
葛根（拉丁学名：Pueraria omeiensis Wang et Tang ）：别名葛条，甘葛，葛藤，味甘微辛，气清香，性凉，主入脾胃经。有发表解肌，升阳透疹，解热生津之功效。用于治疗脾虚泄泻、热病口渴、主治外感发热，头项痛强，麻疹透发不畅，温病口渴，消渴，酒毒，胸痹心痛等病症。现代研究表明，葛根叶和花含有多种人体必须的氨基酸、维生素及黄酮等，具有治疗心脑血管疾病、预防动脉硬化、抗氧化、促进新陈代谢，加强肝脏解毒功能，防止酒精对肝脏的损伤；强化肝胆细胞自身免疫功能，抵抗病毒入侵。在本发明的组方中主要起以下作用：发表退热、生津止渴、解饮酒后口渴，解酒精、解鱼蟹毒；提高肝细胞的再生能力，恢复正常肝脏机能，促进胆汁分泌，防止脂肪在肝脏堆积，有效预防饮酒造成的酒精肝、脂肪肝等作用。
白茅根（拉丁学名：Imperata cylindrica）：别称丝茅草、茅草、白茅草，为禾本科植物多年生草本白茅的根茎。《神农本草经》曰：“茅根，味甘寒。主劳伤虚赢，补中益气，除瘀血血闭寒热，利小便。其苗，主下水。”《名医别录》曰：“茅根，无毒。主下五淋，除客热在肠胃，止渴，坚筋，妇人崩中。久服利人。”具有凉血止血，清热解毒之功效。现代药理学认为，它含淀粉和多量蔗糖、葡萄糖以及少量果糖、木糖、柠檬酸、草酸、苹果酸；其根茎还含甘露醇、薏苡素和芦竹素等成分。它所含丰富的钾盐有良好的利尿作用，煎液对某些痢疾杆菌有明显的抑菌作用。现代临床研究证实本品具有良好的止血、利尿、抗感染的作用，对病毒性肝炎疗效亦颇佳，众多医家都认为它清热利水而不伤肾。
菊花（拉丁学名：Dendranthema morifolium（Ramat. ）Tzvel.）：别称寿客、金英、黄华、秋菊、陶菊、日精、女华、延年、隐逸花，属菊目菊科多年生草本植物，主要成分为挥发油、黄酮类、三萜类及氨基酸、微量元素等，并富含挥发油、菊酮、龙脑、龙脑己酸酯及水苏碱、刺槐甙、木樨草甙、大波斯菊甙、腺膘呤、胆碱、葡萄糖甙等物质成分，具有养肝明目、散风清热、消咳止痛等多种药理活性，对于降低血压、预防高血脂、抗菌、抗病毒、抗炎、抗衰老、治疗冠心病、头痛眩晕、目赤肿痛、风热感冒、咳嗽等病症效果显著。汉朝《神农本草经》记载：“菊花久服能轻身延年”。菊花具有疏风、清热、明目、解毒之功效，并对葡萄球菌、链球菌及绿脓杆菌有抑制及杀灭作用。本发明可以采用黄菊或白菊。
由于采用了上述技术方案，本发明与现有技术相比具有如下有益效果：
本发明的解酒含片中，金花茶、葛根、白茅根、菊花联合使用可以明显增强金花茶的解酒作用，同时提高肝脏乙醇脱氢酶 （alcoholdehydrogenase,ADH）和乙醛脱氢酶的活性，其解酒作用与增强乙醇的生物转化有关。发挥协同解酒作用，对急、慢性酒精中毒均能发挥一定的解酒作用。此外，还具有抗脂质过氧化作用，对肝损伤、肝纤维化以及肝硬化亦具有一定的防治作用。再加上白茅根的协同作用，使解酒作用增强，发挥健胃消食功能，以缓解饮酒过程中过食肥甘引起的肠胃负担；而葛根又能增强肠胃的上下开阖功能；菊花护肝明目，清热解毒，可解酒后虚火。
本发明的解酒含片含有金花茶皂甙、金花茶黄酮、多种氨基酸、微量元素、植物蛋白、维生素等成分，具有缓解酒后发热烦渴，呕逆吐酸等症状，具有憎寒、壮热、解酒醒脾、酒痢、饮食不思、胸膈饱胀、发呃、呕吐酸痰、酒毒伤胃、消热、清肺等功效。其有效成分会在体内激活酒精代谢通路的相关酶类，使得机体迅速分解代谢酒精，促进肝脏解毒、肾脏排泄的功能，起到醒酒、清脑的作用。本发明的解酒含片充分利用了我国传统中医药理论，完全采用大自然药食两用中药，是真正绿色解酒含片，其中含有黄酮类、甙类及萜类化合物，还具有提高免疫能力、抗脂质过氧化、抗肿瘤、抗衰老等生物功能。
具体实施方式
实施例1
以金花茶为原料的解酒含片，由有效成分和辅料制成，有效成分的重量份数如下：金花茶叶15份、葛根叶40份、白茅根10份，菊花15份。
辅料的重量份数如下：山药粉22份、糙米粉22份、甜味剂5份、黄原胶1.5份、卵磷脂1.1份、柠檬酸2.2份和硬脂酸镁1.9份。其中所述甜味剂为果糖3份、甜蜜素2份。
生产方法的工艺步骤如下：
（1）按原料的重量份取金花茶叶、葛根叶、白茅根和菊花；洗净晾干，研磨粉碎，然后加入20倍重量的水，煎煮20分钟，过滤取滤液，再加入2倍无水乙醇，静置2小时，收集醇沉后的上清液，最后向上清液中加入山药粉和糙米粉；
（2）将步骤（1）中含有山药粉和糙米粉的上清液用真空浓缩至膏状，并进行造粒、干燥和整粒处理；
（3）将步骤（2）整粒后的颗粒中加入其它剩余辅料，均匀搅拌混合；最后进行造粒、压片、包装处理得成品。
实施例2
以金花茶为原料的解酒含片，由有效成分和辅料制成，有效成分的重量份数如下：金花茶花25份、葛根叶20份、白茅根20份，菊花30份。
辅料的重量份数如下：山药粉22份、糙米粉22份、甜味剂10份、黄原胶1.5份、卵磷脂1.1份、柠檬酸2.2份和硬脂酸镁1.9份。其中所述甜味剂为果糖3份、木糖醇7份。
生产方法的工艺步骤如下：
（1）按原料的重量份取金花茶花、葛根叶、白茅根和菊花；洗净晾干，研磨粉碎，然后加入25倍重量的水，煎煮25分钟，过滤取滤液，再加入3倍无水乙醇，静置2.5小时，收集醇沉后的上清液，最后向上清液中加入山药粉和糙米粉；
（2）将步骤（1）中含有山药粉和糙米粉的上清液用真空浓缩至膏状，并进行造粒、干燥和整粒处理；
（3）将步骤（2）整粒后的颗粒中加入其它剩余辅料，均匀搅拌混合；最后进行造粒、压片、包装处理得成品。
实施例3
以金花茶为原料的解酒含片，由有效成分和辅料制成，有效成分的重量份数如下：金花茶叶20份、葛根花25份、白茅根17份，菊花20份。
辅料的重量份数如下：山药粉22份、糙米粉22份、甜味剂8份、黄原胶1.5份、卵磷脂1.1份、柠檬酸2.2份和硬脂酸镁1.9份。其中所述甜味剂为麦芽糖醇3份、麦芽糖醇5份。
生产方法的工艺步骤如下：
（1）按原料的重量份取金花茶叶、葛根花、白茅根和菊花；洗净晾干，研磨粉碎，然后加入22倍重量的水，煎煮30分钟，过滤取滤液，再加入2.5倍无水乙醇，静置3小时，收集醇沉后的上清液，最后向上清液中加入山药粉和糙米粉；
（2）将步骤（1）中含有山药粉和糙米粉的上清液用真空浓缩至膏状，并进行造粒、干燥和整粒处理；
（3）将步骤（2）整粒后的颗粒中加入其它剩余辅料，均匀搅拌混合；最后进行造粒、压片、包装处理得成品。
实验例：解酒效果统计资料
临床急性轻中度酒精中毒病例100例，其中男87人，女13人，年龄在17-68岁之间，饮酒后出现的症状有头晕，口干，恶心呕吐，意识不清，行为激动，狂躁不安等，酒后服用本含片2-3片后，在3小时内，病症完全消除的78例，可有效缓解相关症状的16例，无效者6例，有效率94％。
应用实施例1
张某，男，35岁，南宁市某房地产销售，因业务应酬饮53°白酒650ml，饮后面色潮红，说话不清，头晕呕吐，家人为其服用该解酒含片3片及大量温开水2小时后面色潮红褪去，情况好转，又服用2片，30分钟后，说话清晰，呕吐感消失。
应用实施例2
宋某，男，45岁，玉林市某建材公司经理，同学聚餐饮酒50°白酒450ml至酒醉，头晕、说话不清，出现胡言乱语等症状，在建议下服用了该解酒含片3片并饮下大量温开水，60分钟后恢复清醒，头痛减轻，继续服用1片，20分钟后头痛消失，不适症状有所缓解。
应用实施例3
李某，女，27岁，柳州市某银行职员，因感情不顺喝酒宣泄，饮500ml12°啤酒6瓶，恶心呕吐、头疼头晕、脸色涨红、躁动不安，家人让其服用了该解酒含片2片，90分钟后头晕、呕吐感缓解，继续服用1片，休息30分钟后面色、神志恢复正常。
Claims (3)
1.以金花茶为原料的解酒含片，其特征在于，由有效成分和辅料制成，所述有效成分的原料的重量份如下：金花茶叶或茶花15-25份，葛根叶或花20-40份，白茅根10-20份，菊花15-30份。
2.如权利要求1所述的以金花茶为原料的解酒含片，其特征在于：所述的辅料的重量份数为：山药粉22份、糙米粉22份、甜味剂5-10份、黄原胶1.5份、卵磷脂1.1份、柠檬酸2.2份和硬脂酸镁1.9份，其中所述甜味剂为不含蔗糖的甜味剂，为果糖、甜蜜素、木糖醇或麦芽糖醇中的一种或一种以上。
3.一种以金花茶为原料的解酒含片的生产方法，其特征在于：包括以下工艺步骤：
按原料的重量份取金花茶叶或茶花、葛根叶或花、白茅根和菊花；洗净晾干，研磨粉碎，然后加入20-25倍重量的水，煎煮20-30分钟，过滤取滤液，再加入2-3倍重量的无水乙醇，静置2-3小时，收集醇沉后的上清液，最后向上清液中加入山药粉和糙米粉；
将步骤（1）中含有山药粉和糙米粉的上清液用真空浓缩至膏状，并进行造粒、干燥和整粒处理；
将步骤（2）整粒后的颗粒中加入其它剩余辅料，均匀搅拌混合；最后进行造粒、压片、包装处理得成品。
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