CN106687582A - 哺乳动物多能干细胞、其产生方法及其用途 - Google Patents

哺乳动物多能干细胞、其产生方法及其用途 Download PDF

Info

Publication number
CN106687582A
CN106687582A CN201580050219.5A CN201580050219A CN106687582A CN 106687582 A CN106687582 A CN 106687582A CN 201580050219 A CN201580050219 A CN 201580050219A CN 106687582 A CN106687582 A CN 106687582A
Authority
CN
China
Prior art keywords
cells
cell
nedaps
nerve
differentiation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580050219.5A
Other languages
English (en)
Chinese (zh)
Inventor
M·H·黑格内斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Kansas
Original Assignee
University of Kansas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Kansas filed Critical University of Kansas
Publication of CN106687582A publication Critical patent/CN106687582A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/08—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cells of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Materials For Medical Uses (AREA)
CN201580050219.5A 2014-08-04 2015-08-03 哺乳动物多能干细胞、其产生方法及其用途 Pending CN106687582A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462032911P 2014-08-04 2014-08-04
US62/032,911 2014-08-04
PCT/US2015/043424 WO2016022472A1 (en) 2014-08-04 2015-08-03 Mammalian pluripotent stem cells, methods for their production, and uses thereof

Publications (1)

Publication Number Publication Date
CN106687582A true CN106687582A (zh) 2017-05-17

Family

ID=55178918

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580050219.5A Pending CN106687582A (zh) 2014-08-04 2015-08-03 哺乳动物多能干细胞、其产生方法及其用途

Country Status (7)

Country Link
US (2) US20160030484A1 (enExample)
EP (1) EP3194573A4 (enExample)
JP (1) JP6698626B2 (enExample)
CN (1) CN106687582A (enExample)
AU (1) AU2015301342A1 (enExample)
CA (1) CA2957071A1 (enExample)
WO (1) WO2016022472A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109280682A (zh) * 2018-08-31 2019-01-29 华子昂 增强血管内皮细胞表达p选择素的方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6698626B2 (ja) * 2014-08-04 2020-05-27 ユニバーシティ・オブ・カンザス 哺乳動物多能性幹細胞、それらの調製のための方法、およびその使用
CN106222133A (zh) * 2016-06-29 2016-12-14 湛江经济技术开发区海滨医疗器械有限公司 一种利用冲击波使人体间充质干细胞增殖的方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030003572A1 (en) * 1999-03-05 2003-01-02 David J. Anderson Isolation and enrichment of neural stem cells from uncultured tissue based on cell-surface marker expression
CN101492676A (zh) * 2008-09-16 2009-07-29 中国科学院广州生物医药与健康研究院 用脑膜细胞生成诱导的多能性干细胞的方法及其用途
WO2011013806A1 (ja) * 2009-07-30 2011-02-03 学校法人慶應義塾 シュワン前駆細胞の製造方法及び増殖方法
CN102027105A (zh) * 2008-03-17 2011-04-20 斯克里普斯研究所 用于产生诱导的多能干细胞的组合化学遗传方法
CN102066556A (zh) * 2008-05-27 2011-05-18 马克斯-普朗克科学促进协会 诱导性多能干(iPS)细胞的产生
CN102191221A (zh) * 2010-03-17 2011-09-21 中国人民解放军第二军医大学东方肝胆外科医院 一种能无限自我更新的神经干细胞、其制备方法及其用途
WO2013188744A1 (en) * 2012-06-15 2013-12-19 Baylor College Of Medicine Perineurium derived adult stem cells and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110134939A (ko) * 2009-04-03 2011-12-15 더 맥클린 하스피털 코퍼레이션 유도된 다능성 줄기 세포
US8193235B2 (en) * 2009-06-12 2012-06-05 University Of Kansas Compositions and methods for establishing and maintaining stem cells in an undifferentiated state
CN102725399B (zh) 2009-12-18 2015-03-11 上海赛傲生物技术有限公司 制备多能干细胞的材料和方法
EP2537922B1 (en) * 2010-02-18 2021-04-21 Kang Stem Biotech Co., Ltd. Cd49f promoting proliferation, multipotency and reprogramming of adult stem cells through pi3k/akt/gsk3 pathway
WO2011108766A1 (en) * 2010-03-03 2011-09-09 Kyoto University METHOD FOR DIAGNOSING A PROTEIN MISFOLDING DISEASE USING NERVE CELLS DERIVED FROM iPS CELLS
US20120069782A1 (en) * 2010-09-22 2012-03-22 Richard Lee-Chee Kuo Method and apparatus for improving drx in a wireless communication system
JP6698626B2 (ja) * 2014-08-04 2020-05-27 ユニバーシティ・オブ・カンザス 哺乳動物多能性幹細胞、それらの調製のための方法、およびその使用

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030003572A1 (en) * 1999-03-05 2003-01-02 David J. Anderson Isolation and enrichment of neural stem cells from uncultured tissue based on cell-surface marker expression
CN102027105A (zh) * 2008-03-17 2011-04-20 斯克里普斯研究所 用于产生诱导的多能干细胞的组合化学遗传方法
CN102066556A (zh) * 2008-05-27 2011-05-18 马克斯-普朗克科学促进协会 诱导性多能干(iPS)细胞的产生
CN101492676A (zh) * 2008-09-16 2009-07-29 中国科学院广州生物医药与健康研究院 用脑膜细胞生成诱导的多能性干细胞的方法及其用途
WO2011013806A1 (ja) * 2009-07-30 2011-02-03 学校法人慶應義塾 シュワン前駆細胞の製造方法及び増殖方法
CN102191221A (zh) * 2010-03-17 2011-09-21 中国人民解放军第二军医大学东方肝胆外科医院 一种能无限自我更新的神经干细胞、其制备方法及其用途
WO2013188744A1 (en) * 2012-06-15 2013-12-19 Baylor College Of Medicine Perineurium derived adult stem cells and methods of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
YANG SY等: "Differentiation of nerve-derived adult pluripotent stem cells into osteoblastic and endothelial cells", 《SPINE J》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109280682A (zh) * 2018-08-31 2019-01-29 华子昂 增强血管内皮细胞表达p选择素的方法

Also Published As

Publication number Publication date
WO2016022472A1 (en) 2016-02-11
US20160030484A1 (en) 2016-02-04
AU2015301342A1 (en) 2017-03-02
CA2957071A1 (en) 2016-02-11
EP3194573A4 (en) 2018-01-17
US20190218543A1 (en) 2019-07-18
EP3194573A1 (en) 2017-07-26
JP6698626B2 (ja) 2020-05-27
JP2017529066A (ja) 2017-10-05
US10787658B2 (en) 2020-09-29

Similar Documents

Publication Publication Date Title
KR100973453B1 (ko) 인간 배아 줄기 세포에서 유래되는 연골세포 전구체
KR101874463B1 (ko) 세포의 재프로그램화 방법 및 이의 용도
RU2306335C2 (ru) Стволовые клетки и решетки, полученные из жировой ткани
Mantovani et al. Isolation of adult stem cells and their differentiation to Schwann cells
KR101669038B1 (ko) 영양막 기저층으로부터 유래된 줄기세포 및 이를 포함하는 세포치료제
JP2021534813A (ja) 非免疫原性の操作された組織ならびにそれを製造および使用する方法
CN109689858A (zh) 用于产生具有体内血管形成能力的中胚层和/或内皮集落形成细胞样细胞的方法
US10787658B2 (en) Mammalian pluripotent stem cells, methods for their production, and uses thereof
EP1819809A2 (en) Compositions and methods for stem cell expansion and differentiation
US20140193377A1 (en) Preparation of parental cell bank from foetal tissue
Saxena et al. Role of stem cell research in therapeutic purpose--a hope for new horizon in medical biotechnology.
Liu et al. Construction of tissue-engineered nerve conduits seeded with neurons derived from hair-follicle neural crest stem cells
KR102121417B1 (ko) Stat3 활성화제를 이용한 골격근세포 분화 유도용 조성물 및 이를 이용한 골격근세포 분화 유도 방법
Caglayan et al. Modern ways of obtaining stem cells
KR20160144780A (ko) 편도 유래 중간엽 줄기세포로부터 건 세포의 분화방법
Kraus et al. Non-viral genetic transfection of rat Schwann cells with FuGENE HD© lipofection and AMAXA© nucleofection is feasible but impairs cell viability
KR102182646B1 (ko) 줄기세포 치료제의 치료효과를 향상시키기 위한 방법 및 조성물
Edaso et al. Review on applications of stem cells in veterinary therapeutic practices
Deng et al. Novel 3D bioprinting approach for spinal cord injury repair using neural stem cells and TGF-β1 monoclonal antibody
JP6654323B2 (ja) 重層上皮組織形成能を有する細胞、及びその製造方法
Wakao et al. Induction of Schwann Cells from Rat Bone Marrow Mesenchymal Stem Cells
Sun et al. Pluripotent Stem Cells Can Be Isolated from Human Peripheral Nerves after in vitro BMP-2 Stimulation
WO2019093047A1 (ja) インビトロでの機能的な外分泌腺の製造方法、および、当該方法によって製造される外分泌腺
Shawcross et al. Isolation and differentiation of Schwann progenitor cells: Isolation and differentiation of Schwann progenitor cells

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20170517

WD01 Invention patent application deemed withdrawn after publication