CN106620515A - Traditional Chinese medicine composition for treating pork sporozoosis - Google Patents

Traditional Chinese medicine composition for treating pork sporozoosis Download PDF

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CN106620515A
CN106620515A CN201611100335.6A CN201611100335A CN106620515A CN 106620515 A CN106620515 A CN 106620515A CN 201611100335 A CN201611100335 A CN 201611100335A CN 106620515 A CN106620515 A CN 106620515A
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张俊清
张明
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Abstract

The invention discloses a traditional Chinese medicine composition for treating pork sporozoosis and belongs to the technical field of traditional Chinese veterinary medicines. The traditional Chinese medicine composition is composed of the following components in parts by weight: 8-25 parts of ferula asafoetida, 6-20 parts of radix sophorae flavescentis, 5-20 parts of embelia laeta, 5-20 parts of Iris qinghainica Y.T.Zhao, 5-25 parts of hematoxylon, 8-25 parts of cleavers, 5-20 parts of radix semiaquilegiae, 9-25 parts of gentianaalgida, 5-20 parts of dracocephalum tanguticum maxim, 8-25 parts of picris japonica, 6-20 parts of roasted radix bupleuri, 9-25 parts of radix curcumae, 8-20 parts of fructus aurantii, 3-15 parts of Chinese gall leaven, 5-25 parts of cotton roots, 5-20 parts of saffron crocus, 8-25 parts of Chinese incarvilla herb and 8-20 parts of glycyrrhiza prepared with honey. The composition disclosed by the invention has the characteristics of being insecticidal and detoxicant, invigorating the circulation of blood to dissipate blood stasis and eliminating swelling and settling pain, and also has insecticidal and beneficial effects. By combining a modern inspection technique to verify, the traditional Chinese medicine composition is exact in curative effect and free of any toxic or side effects in clinical application.

Description

A kind of Chinese medicine composition for treating Sarcocystis miescheriana disease
Technical field
The invention belongs to technical field of Chinese veterinary medicine, in particular, belongs to a kind of Chinese medicine group for treating Sarcocystis miescheriana disease Compound.
Background technology
Sarcocystis miescheriana disease is pork pies worm section in prior art, and sarcocystis subfamily, many hosts of Miescheria post Infested disease.The disease has presence in addition to China in Asia, and sarcocystis can also parasitize human body, to colonize in intramuscular For main feature.
Pathogen:The species of Sarcocystis miescheriana cause of disease host and different from the relation of people and have different polypides, below Several frequently seen sarcocystis kind, people Sarcocystis miescheriana (sarcocystissuihominis), Sarcocystis blanchardi (S.fusifor-mis), Sarcocystis hominis (S.hominis), sarcocystis bertrami (S.bertrami), Sarcocystis tenella , and mouse sporozoite (S.muris) etc. (S.tenella).
Sarcocystis form and the history of life:Sarcocyst is in cylinder or spindle, and size difference is very big;Have in cyst wall Many intervals separate cluster intracapsular polypide-bradyzoite.Ripe egg capsule, oblong, includes 2 sporangiums.Sporangium is in ellipse Circular or oval, wall is double-deck and transparent, includes 4 zygoblasts.
After sporangium or egg capsule in definitive host's excrement is eaten by intermediate host's (herbivore), zygoblast escapes in its little enteral Go out, through intestinal wall blood is entered, formed in endothelial cell and split after row several generations schizogony, merozoite enters muscle groups It is sarcocyst to knit middle development.Trophoblast or title mother cell in sarcocyst, propagation generates bradyzoite.Intermediate host After sarcocyst in muscle is eaten by definitive host, bradyzoite disengages and invades little intestinal lamina propria, directly forms gamete, male and female Gamete is combined into egg capsule, gradually reaches maturity.
Sarcocystis miescheriana primary symptom:There is symptom of digestive tract such as intermittent stomachache, abdominal distension, borborygmus, diarrhoea, appetite not in sick pig Shake, severe patient can occur anaemia, necrotic enteritis.Sarcocyst can destroy invaded myocyte, cause adjacent cells Pressure atrophy, with myalgia, subcutaneous swelling etc..When pig severe infections, every gram of pig diaphram has more than 50 spore polypides, then Sick pig performance is uneasy, and back is powerless, muscle rigidity occurs, and sometimes the hind leg of sick pig can paralyse, and has expiratory dyspnea performance.Firmly meat Sporozoite cyst wall can discharge a kind of pork pies toxin when rupturing, and toxicity is very strong, can act on sick pig nerve, heart, kidney Gland, liver and small intestine, disease serious later stage sporozoite polypide amount reproduction in sick pig body is parasitic, causes when can secrete a large amount of toxin Sick pig miscarriage, even death.After pork with Pathological observation is freezed 26 days below refrigerated environment, 18 degrees below zero, use aobvious Micro mirror microscopy, sarcocystis still survives and can not be freezed to death, and edible freezing is absolutely unsafe with firmly sporozoan meat, Ke Yizao The infected firmly sporidiosis of adult.
Sarcocystis miescheriana diagnoses:This disease generally checks excrement miospore capsule or egg capsule, immunodiagnosis with zinc sulfate floatation method Indirect thrombotest, EUSA can be adopted.
Prior art treatment Sarcocystis miescheriana disease, there is no at present specific medicament, mostly with salinomycin, Amprolium hydrochloride anticoccidial drug Based on thing treatment, sporidiosis is treated using said medicine, stimulate infringement strong sick pig liver kidney organ, drug residue is big, controls Therapeutic effect has much room for improvement.
The content of the invention
The present invention gives a kind of Chinese traditional medicine composition for treating Sarcocystis miescheriana disease to efficiently solve above technical problem Thing.
A kind of Chinese medicine composition for treating Sarcocystis miescheriana disease of the present invention, it is characterised in that constitute by following weight portion: Asafoetide 8-25 parts, kuh-seng 6-20 parts, common embelia fruit 5-20 parts, the sub- 5-20 parts of Qinghai iris, bush 5-25 parts, clearvers 8-25 parts, Radix semiaquilegiae 5-20 parts, alpine gentian 9-25 parts, Tang Gute ultramarine 5-20 parts, hair lotus dish 8-25 parts, process radix bupleuri 6-20 parts, root tuber of aromatic turmeric 9- 25 parts, Fructus Aurantii 8-20 parts, fermented Chinese gall herb and tea leaves 3-15 parts, Levant Cotton Root 5-25 parts, safflower 5-20 parts, Chinese Incarvilla Herb 8-25 parts, Radix Glycyrrhizae (processed with honey) 8- 20 parts.
The Chinese medicine composition for the treatment of Sarcocystis miescheriana disease in accordance with the above, it is preferable that constitute by following weight portion:Asafoetide 8 parts, 6 parts of kuh-seng, 5 parts of common embelia fruit, Qinghai iris 5 parts, 5 parts of bush, 8 parts of clearvers, 5 parts of radix semiaquilegiae, 9 parts of alpine gentian, 8 parts of part, mao lotus dish of Tang Gute ultramarine 5, process 6 parts of radix bupleuri, 9 parts of root tuber of aromatic turmeric, 8 parts of Fructus Aurantii, 3 parts of fermented Chinese gall herb and tea leaves, 5 parts of Levant Cotton Root, safflower 5 Part, 8 parts of Chinese Incarvilla Herb, 8 parts of Radix Glycyrrhizae (processed with honey).
The Chinese medicine composition for the treatment of Sarcocystis miescheriana disease in accordance with the above, it is preferable that constitute by following weight portion:Asafoetide 25 parts, 20 parts of kuh-seng, 20 parts of common embelia fruit, Qinghai iris 20 parts, 25 parts of bush, 25 parts of clearvers, 20 parts of radix semiaquilegiae, high mountain dragon 25 parts of courage, 25 parts of part, mao lotus dish of Tang Gute ultramarine 20, process 20 parts of radix bupleuri, 25 parts of root tuber of aromatic turmeric, 20 parts of Fructus Aurantii, 15 parts of fermented Chinese gall herb and tea leaves, cotton 25 parts of root, 20 parts of safflower, 25 parts of Chinese Incarvilla Herb, 20 parts of Radix Glycyrrhizae (processed with honey).
The Chinese medicine composition for the treatment of Sarcocystis miescheriana disease in accordance with the above, it is preferable that constitute by following weight portion:Asafoetide 9 parts, 7 parts of kuh-seng, 6 parts of common embelia fruit, Qinghai iris 7 parts, 8 parts of bush, 10 parts of clearvers, 7 parts of radix semiaquilegiae, alpine gentian 11 Part, 9 parts of part, mao lotus dish of Tang Gute ultramarine 7, process 8 parts of radix bupleuri, 11 parts of root tuber of aromatic turmeric, 10 parts of Fructus Aurantii, 5 parts of fermented Chinese gall herb and tea leaves, 7 parts of Levant Cotton Root, hide 6 parts of safflower, 10 parts of Chinese Incarvilla Herb, 10 parts of Radix Glycyrrhizae (processed with honey).
The Chinese medicine composition for the treatment of Sarcocystis miescheriana disease in accordance with the above, it is preferable that constitute by following weight portion:Asafoetide 11 parts, 9 parts of kuh-seng, 8 parts of common embelia fruit, Qinghai iris 9 parts, 10 parts of bush, 12 parts of clearvers, 9 parts of radix semiaquilegiae, alpine gentian 13 Part, 11 parts of part, mao lotus dish of Tang Gute ultramarine 9, process 10 parts of radix bupleuri, 13 parts of root tuber of aromatic turmeric, 12 parts of Fructus Aurantii, 7 parts of fermented Chinese gall herb and tea leaves, 9 parts of Levant Cotton Root, 8 parts of safflower, 12 parts of Chinese Incarvilla Herb, 12 parts of Radix Glycyrrhizae (processed with honey).
The Chinese medicine composition for the treatment of Sarcocystis miescheriana disease in accordance with the above, it is preferable that constitute by following weight portion:Asafoetide 13 parts, 11 parts of kuh-seng, 10 parts of common embelia fruit, Qinghai iris 12 parts, 12 parts of bush, 14 parts of clearvers, 11 parts of radix semiaquilegiae, high mountain dragon 15 parts of courage, 13 parts of part, mao lotus dish of Tang Gute ultramarine 14, process 12 parts of radix bupleuri, 15 parts of root tuber of aromatic turmeric, 14 parts of Fructus Aurantii, 9 parts of fermented Chinese gall herb and tea leaves, cotton 12 parts of root, 10 parts of safflower, 14 parts of Chinese Incarvilla Herb, 14 parts of Radix Glycyrrhizae (processed with honey).
The Chinese medicine composition for the treatment of Sarcocystis miescheriana disease in accordance with the above, it is preferable that constitute by following weight portion:Asafoetide 16 parts, 13 parts of kuh-seng, 12 parts of common embelia fruit, Qinghai iris 14 parts, 15 parts of bush, 16 parts of clearvers, 13 parts of radix semiaquilegiae, high mountain dragon 17 parts of courage, 15 parts of part, mao lotus dish of Tang Gute ultramarine 16, process 14 parts of radix bupleuri, 17 parts of root tuber of aromatic turmeric, 16 parts of Fructus Aurantii, 12 parts of fermented Chinese gall herb and tea leaves, cotton 15 parts of root, 12 parts of safflower, 16 parts of Chinese Incarvilla Herb, 16 parts of Radix Glycyrrhizae (processed with honey).
The Chinese medicine composition for the treatment of Sarcocystis miescheriana disease in accordance with the above, it is preferable that constitute by following weight portion:Asafoetide 19 parts, 15 parts of kuh-seng, 14 parts of common embelia fruit, Qinghai iris 14 parts, 18 parts of bush, 18 parts of clearvers, 16 parts of radix semiaquilegiae, high mountain dragon 20 parts of courage, 17 parts of part, mao lotus dish of Tang Gute ultramarine 18, process 16 parts of radix bupleuri, 19 parts of root tuber of aromatic turmeric, 18 parts of Fructus Aurantii, 14 parts of fermented Chinese gall herb and tea leaves, cotton 17 parts of root, 14 parts of safflower, 18 parts of Chinese Incarvilla Herb, 17 parts of Radix Glycyrrhizae (processed with honey).
The Chinese medicine composition for the treatment of Sarcocystis miescheriana disease in accordance with the above, it is preferable that constitute by following weight portion:Asafoetide 22 parts, 17 parts of kuh-seng, 16 parts of common embelia fruit, Qinghai iris 16 parts, 20 parts of bush, 20 parts of clearvers, 19 parts of radix semiaquilegiae, high mountain dragon 22 parts of courage, 20 parts of part, mao lotus dish of Tang Gute ultramarine 19, process 18 parts of radix bupleuri, 21 parts of root tuber of aromatic turmeric, 19 parts of Fructus Aurantii, 11 parts of fermented Chinese gall herb and tea leaves, cotton 20 parts of root, 16 parts of safflower, 20 parts of Chinese Incarvilla Herb, 18 parts of Radix Glycyrrhizae (processed with honey).
The Chinese medicine composition for the treatment of Sarcocystis miescheriana disease in accordance with the above, it is preferable that constitute by following weight portion:Asafoetide 24 parts, 19 parts of kuh-seng, 18 parts of common embelia fruit, Qinghai iris 18 parts, 22 parts of bush, 23 parts of clearvers, 17 parts of radix semiaquilegiae, high mountain dragon 24 parts of courage, 23 parts of part, mao lotus dish of Tang Gute ultramarine 17, process 19 parts of radix bupleuri, 23 parts of root tuber of aromatic turmeric, 16 parts of Fructus Aurantii, 13 parts of fermented Chinese gall herb and tea leaves, cotton 23 parts of root, 18 parts of safflower, 22 parts of Chinese Incarvilla Herb, 19 parts of Radix Glycyrrhizae (processed with honey).
Property of medicine effect of each component in present invention treatment Sarcocystis miescheriana disease Chinese medicine composition:
Asafoetide:Nature and flavor:Bitter, pungent, temperature.Return through:Return liver, spleen, stomach.Effect:Desinsection, change product.Cure mainly:Abdominal pain due to enterositosis, the stasis of blood Mass formed by blood stasis lump in the abdomen, mass in abdomen, anasarca.
Kuh-seng:Nature and flavor:It is bitter, cold.Return through:The thoughts of returning home, liver, large intestine, small intestine, stomach.Effect:Desinsection heat-clearing.Cure mainly:Damp and hot Huang Subcutaneous ulcer, intestines Huang rushes down, the disease such as hygropyretic hematochezia.
Common embelia fruit:Nature and flavor:It is sweet, sour, pungent.It is warm in nature, imitate dry, sharp.Return through:Return liver, spleen, stomach.Effect:Desinsection is subsided a swelling.It is main Control:It is strong enrich blood, gastric anacidity, poor appetite.
Qinghai iris:Nature and flavor:It is hardship, micro-sweet, cool.Return through:Large intestine channel.Effect:Clearing heat and detoxicating, desinsection.Cure mainly:Acute appendicitis, Rush down dysentery.
Bush:Nature and flavor:It is sweet, it is salty, put down.Return through:The thoughts of returning home, liver, stomach, large intestine channel.Effect:Promoting blood circulation, detumescence ding-tong.It is main Control:Amenorrhea due to stagnation of blood, stasis blocking stomachache, bruise dusk are vexed.
Clearvers:Nature and flavor:Fortunately, it is bitter, cool.Return through:Return.Effect:Clearing heat and detoxicating, inducing diuresis to remove edema.Cure mainly:Oedema, external application are controlled Mastitis from the beginning of.
Radix semiaquilegiae:Nature and flavor:Sweet, hardship, it is cold in nature.Return liver, stomach.Effect:It is clearing heat and detoxicating, dispersing swelling and dissipating binds.Cure mainly:Carbuncle swells malignant boil Sore, acute mastitis, scrofula.
Alpine gentian:Nature and flavor:It is bitter, cold.Return through:Return liver, courage, stomach.Effect:For heat-clearing and damp-drying drug, purging the liver of pathogenic fire courage excess fire.Dehumidifying Heat, cough-relieving is coughed, strengthening the spleen and stomach.
Tang Gute ultramarine:Nature and flavor:It is bitter, cold.Effect:Soothing the liver with stomach, clearing liver stomach heat.
Hair lotus dish:Nature and flavor:It is bitter, cold.Return through:Return liver, kidney, stomach, small intestinl channel.Effect:Anti inflammation and heat resolution, liver protection dampness removing.Cure mainly: Anti-inflammatory, diuresis, detumescence.
Process radix bupleuri:Nature and flavor:It is bitter, cold.Return through:Return liver, courage, pericardium, tri-jiao channel.Effect:It is soothing liver-gallbladder, regulating qi-flowing for relieving pain, clear The liver solution stasis of blood, yang invigorating, evacuation are brought down a fever.Cure mainly:Cold, fever, fevers and chills alternate, malaria, stagnation of QI due to depression of the liver, sternal rib pain, prolapse of the anus, Uterus comes off.
Root tuber of aromatic turmeric:Nature and flavor:Cold, pungent, hardship.Return through:Return liver, the heart, lung channel.Effect:Normalizing gallbladder to cure jaundice, regulating qi to disperse stagnation, the solution that the clears away heart-fire stasis of blood. Cure mainly:Jaundice urine is red, chest and abdomen swelling and pain.
Fructus Aurantii:Nature and flavor:Acid, be slightly cold.Return through:Returns spleen, liver, stomach, large intestine channel.Effect:Regulating the flow of QI to ease the stomach, the stagnant detumescence of row.Cure mainly: Chest flatulence is stagnant, stop in turgor pain, accumulation of food in the stomach and intes tine due to indigestion, phlegm and retained fluid.
Fermented Chinese gall herb and tea leaves:Nature and flavor:It is sour, sweet, flat.Return through:Attach to the lung and stomach meridians.Effect:Moistening lung for removing phlegm, relieving diarrhea with astringents.Cure mainly:For Chronic diarrhea caused by chronic cough of deficiency lung, deficiency of spleen-QI, the sinking of qi of middle-jiao.
Levant Cotton Root:Nature and flavor:Sweet, temperature.Return through:Returns spleen Jing.Effect:Invigorate the spleen and benefit qi, expectorant cough suppressant and anti-asthmatic, invigorating the spleen for eliminating dampness.
Safflower:Nature and flavor:Warm, sweet, micro-pungent, slight bitter, it is mild-natured.Return through;The thoughts of returning home, Liver Channel.Effect:Blood-nourishing, invigorate blood circulation, enrich blood, Promoting circulation of blood, regulating blood condition, dissolving stasis, dredging collateral.Cure mainly;Anemia body void, extravasated blood, have aches and pains all over, the symptom tool such as melancholy vexed knot improves significantly Effect.
Chinese Incarvilla Herb:Nature and flavor:It is sweet, bitter, temperature.Return liver, spleen, kidney channel.Effect:Blood-nourishing is enriched blood, and is the medicine of strengthening by means of tonics, is cured mainly:It is lean Blood, weakness due to chronic disease.
Radix Glycyrrhizae (processed with honey):Nature and flavor:It is flat, sweet.Return through:Return 12 warps.Effect:Tonifying Qi and in, relax the property of medicine, emergency analgesic therapy, solution The work(of poison.Cure mainly:Weakness of the spleen and the stomach, expelling phlegm and arresting coughing.Radix Glycyrrhizae (processed with honey) enhancing moistens the lung and relieve the cough, tonifying middle-Jiao and Qi effect, each medicine in mitigation side The property of medicine, lowers toxic and side effect.
The principle of reatment of the present invention:Desinsection removing toxic substances, promoting blood circulation to remove blood stasis, detumescence ding-tong, benefiting qi and nourishing blood.
Fang Xie:In side with asafoetide, kuh-seng, common embelia fruit, Qinghai iris as monarch drug in a prescription, killing insect and eliminating accumulation, clearing heat for detumescence, play because Cloudy distribution heat caused by sarcocystis, it is evil outgoing to draw outward by not hot, strongly fragrant heat in the interior;With bush, clearvers, radix semiaquilegiae, high mountain Rough gentian, tangut dragonhead, hair lotus dish are ministerial drug, promoting blood circulation to remove blood stasis, clearing heat and detoxicating, alleviate what the toxin of polypide release was caused to sick pig Toxic and side effect;To process radix bupleuri, root tuber of aromatic turmeric, Fructus Aurantii, fermented Chinese gall herb and tea leaves, Levant Cotton Root, safflower, Chinese Incarvilla Herb as adjutant, regulating qi-flowing for relieving pain, promoting the circulation of qi The stasis of blood, training fill blood, invigorating the spleen to arrest diarrhea, and drive benefit is simultaneous to be applied, suck sarcocystis carcass water paddy elite, consumption wound to assist the medicine of the monarch and his subjects two to play Qi and blood has benefiting action;With Radix Glycyrrhizae (processed with honey) to make medicine, coordinating the drug actions of a prescription, the gentle property of medicine, priming return through;Above each medicine is closed and used It, desinsection is trained and filled blood simultaneously, and drive benefit is simultaneous to be applied, and is treated both principal and secondary aspect of disease, and cures Sarcocystis miescheriana disease.
The beneficial effect of the present invention and prior art:The middle pharmaceutical composition of the present invention provides a kind of evident in efficacy, safety The Traditional Chinese medicine composition formula of reliable treatment Sarcocystis miescheriana disease.
The Chinese medicine composition and existing western medical treatment Sarcocystis blanchardi disease of the present invention is using the difference of chemicals maximum, Change the outdated ideas of medication on veterinary clinic for many years, due to long-term abuse chemicals treatment animal parasite disease, cause house Poultry non-specific immunity is low, and medicine is in, and carcass is interior to be remained and manure contamination environment, and harm food security is strong to the mankind Health threatens, and to the prevention and control of the disease of domestic animals adverse consequences is brought, and Long-Time Service chemotherapy animal parasite is sick, There is the off-drug period, national standing order is forbidden to butcher edible ill domestic animal meat, dairy products, because chemicals is in domestic animal within the off-drug period Decomposition cannot be fully absorbed by carcass in vivo, easily produce poisoning, the excreta of pig is excreted to and causes secondary to environment in vitro Pollution, is the drawbacks of widely using chemical drug at present.
Chinese medicinal material raw material thoroughly solves problem above, and medicinal material is natural, and drug effect can fully absorb decomposition by ill domestic animal, disease Pig excrements environmental protection, Chinese medicine as Specialty bio active additive, can adjust the new katabolism of body, promote the suction of nutriment Receive, improve domestic animal resistance against diseases.
With treatment by Chinese herbs Sarcocystis miescheriana disease, the desinsection removing toxic substances advantage having, what is taken due to Chinese medicine is personalized Compound preparation, has specific aim to illness, over the course for the treatment of the diversification of effective components of Chinese medicinal, and sarcocystis body is difficult to it Produce drug resistance so that Chinese medicine has remarkable result and clear superiority in terms for the treatment of sarcocystis disease.
Specific embodiment
Preferred embodiment 1
The Chinese medicine composition of the treatment Sarcocystis miescheriana disease of present embodiment, is constituted by following weight portion:8 parts of asafoetide, hardship 6 parts of ginseng, 5 parts of common embelia fruit, 5 parts of Qinghai iris, 5 parts of bush, 8 parts of clearvers, 5 parts of radix semiaquilegiae, 9 parts of alpine gentian, Tang Gute 8 parts of part, mao lotus dish of ultramarine 5, process 6 parts of radix bupleuri, 9 parts of root tuber of aromatic turmeric, 8 parts of Fructus Aurantii, 3 parts of fermented Chinese gall herb and tea leaves, 5 parts of Levant Cotton Root, 5 parts of safflower, angle 8 parts of wormwood artemisia, 8 parts of Radix Glycyrrhizae (processed with honey).
Preparation method one
Step one, by 8 parts of asafoetide, 6 parts of kuh-seng, 5 parts of common embelia fruit, Qinghai iris 5 parts, 5 parts of bush, clearvers 8 part, day 5 parts of certain herbaceous plants with big flowers, 9 parts of alpine gentian, 8 parts of part, mao lotus dish of Tang Gute ultramarine 5, process 6 parts of radix bupleuri, 9 parts of root tuber of aromatic turmeric, 8 parts of Fructus Aurantii, fermented Chinese gall herb and tea leaves 3 Part, 5 parts of Levant Cotton Root, 5 parts of safflower, 8 parts of Chinese Incarvilla Herb, 8 parts of Radix Glycyrrhizae (processed with honey) are well mixed, and every part of active compound quality is one gram, plus Chinese medicine The distilled water immersion that 5 times of gross weight is decocted 3 times after 24 hours, is maintained 0.5 hour after boiling every time, and collecting decoction is simultaneously concentrated into Thick shape concentrate;
Step 2, in concentrate plus concentration is that 95% ethanol is adjusted to determining alcohol for 20%, be sufficiently stirred for mixing, stand and sink Form sediment 24 hours, filter, filtrate recycling ethanol, reclaim the liquid after ethanol and add the ethanol that concentration is 95% to be adjusted to determining alcohol again to be 30%, stir evenly, staticly settle 48 hours, filter, filtrate recycling ethanol is further concentrated to without alcohol taste, the dosing in the liquid after concentration - 4 DEG C of refrigerations of 0 DEG C of amount distilled water of 4 times of liquid, staticly settle 48 hours;
Step 3, filtration obtain filtrate, and filtrate is concentrated into per 1.5 milliliters containing 1 gram of dose, obtains obtained liquid;Circulation Steam sterilizing is obtained final product makes oral liquid formulations.
Preparation method two
Step one, by 8 parts of asafoetide, 6 parts of kuh-seng, 5 parts of common embelia fruit, Qinghai iris 5 parts, 5 parts of bush, clearvers 8 part, day 5 parts of certain herbaceous plants with big flowers, 9 parts of alpine gentian, 8 parts of part, mao lotus dish of Tang Gute ultramarine 5, process 6 parts of radix bupleuri, 9 parts of root tuber of aromatic turmeric, 8 parts of Fructus Aurantii, fermented Chinese gall herb and tea leaves 3 Part, 5 parts of Levant Cotton Root, 5 parts of safflower, 8 parts of Chinese Incarvilla Herb, 8 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, is stirred in input mixer Mix, mix;
Step 2, be re-fed in pulverizer crush, the Chinese medicine composition after crushing is fitted in multi-function extractor, addition Relative to 8 times of water measured of its quality, boil 3 hours, steam pressure is 0.6Mpa process, filters, and obtains the first filtered fluid and filter Slag;
Step 3, the filter residue of acquisition is added again water relative to 6 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, is filtrated to get the second filtered fluid and filter residue;First filtered fluid and the second filtered fluid are merged, concentration removes moisture and obtains Get dry extract;
Step 4, crushed using super-fine powder mill, be crushed to below 30-50 microns acquisition Chinese medicine micropowders preparation, put Enter sealing in vessel standby.
Preparation method three
Step one, by 8 parts of asafoetide, 6 parts of kuh-seng, 5 parts of common embelia fruit, Qinghai iris 5 parts, 5 parts of bush, clearvers 8 part, day 5 parts of certain herbaceous plants with big flowers, 9 parts of alpine gentian, 8 parts of part, mao lotus dish of Tang Gute ultramarine 5, process 6 parts of radix bupleuri, 9 parts of root tuber of aromatic turmeric, 8 parts of Fructus Aurantii, fermented Chinese gall herb and tea leaves 3 Part, 5 parts of Levant Cotton Root, 5 parts of safflower, 8 parts of Chinese Incarvilla Herb, 8 parts of Radix Glycyrrhizae (processed with honey), are well mixed, and every part of active compound quality is one gram, and medicine is total Weight is designated as portion, and add water 8 times of weight, decocts 3 hours, and add water for the second time 6 times of weight, decocts 2 hours;
Step 2, decoction liquor are filtered and obtain filtrate, and filtrate is concentrated into the clear cream that relative density is 1.23-1.33 (65 DEG C);
Mix in step 3, clear cream plus after appropriate amount of starch, be dried, crush, plus appropriate amount of ethanol is made and be dried after particle, it is whole Grain, obtains final product composition grain preparation.
The usage and dosage of Chinese medicine composition of the present invention:1st, pulvis, usage and dosage:It is for oral administration, by pig body weight 2g/kg dosage, often Day 1 time, be used in conjunction 8-10 days.2nd, oral liquid, usage and dosage:For oral administration, by pig body weight 3ml/kg dosage, one time a day, is used in conjunction 8-10 My god.3rd, granule, usage and dosage:For oral administration, by pig body weight 2g/kg dosage, one time a day, is used in conjunction 8-10 days.Or according to this enforcement The Chinese medicine preparation of example directly soaks Chinese medicine composition mixing, then carries out infusion and obtains traditional Chinese herbal decoction, according to the body weight of sick pig Choose appropriate decoction and directly sick pig is gavaged daily one, be used in conjunction 8-10 days.
Preferred embodiment 2
The Chinese medicine composition of the treatment Sarcocystis miescheriana disease of present embodiment, is constituted by following weight portion:25 parts of asafoetide, hardship Ginseng 20 parts, 20 parts of common embelia fruit, Qinghai iris 20 parts, 25 parts of bush, 25 parts of clearvers, 20 parts of radix semiaquilegiae, 25 parts of alpine gentian, 25 parts of part, mao lotus dish of Tang Gute ultramarine 20, process 20 parts of radix bupleuri, 25 parts of root tuber of aromatic turmeric, 20 parts of Fructus Aurantii, 15 parts of fermented Chinese gall herb and tea leaves, 25 parts of Levant Cotton Root, 20 parts of safflower, 25 parts of Chinese Incarvilla Herb, 20 parts of Radix Glycyrrhizae (processed with honey).
Preparation method one
Step one, by 25 parts of asafoetide, 20 parts of kuh-seng, 20 parts of common embelia fruit, Qinghai iris 20 parts, 25 parts of bush, clearvers 25 parts, 20 parts of radix semiaquilegiae, 25 parts of alpine gentian, 25 parts of part, mao lotus dish of Tang Gute ultramarine 20, process 20 parts of radix bupleuri, 25 parts of root tuber of aromatic turmeric, trifoliate orange 20 parts of shell, 15 parts of fermented Chinese gall herb and tea leaves, 25 parts of Levant Cotton Root, 20 parts of safflower, 25 parts of Chinese Incarvilla Herb, 20 parts of Radix Glycyrrhizae (processed with honey) are well mixed, per part of original Medicine quality is one gram, plus the distilled water immersion of 5 times of Chinese medicine gross weight is after 24 hours, is decocted 3 times, and maintenance 0.5 is little after boiling every time When, collecting decoction is simultaneously concentrated into thick shape concentrate;
Step 2, in concentrate plus concentration is that 95% ethanol is adjusted to determining alcohol for 20%, be sufficiently stirred for mixing, stand and sink Form sediment 24 hours, filter, filtrate recycling ethanol, reclaim the liquid after ethanol and add the ethanol that concentration is 95% to be adjusted to determining alcohol again to be 30%, stir evenly, staticly settle 48 hours, filter, filtrate recycling ethanol is further concentrated to without alcohol taste, the dosing in the liquid after concentration - 4 DEG C of refrigerations of 0 DEG C of amount distilled water of 4 times of liquid, staticly settle 48 hours;
Step 3, filtration obtain filtrate, and filtrate is concentrated into per 1.5 milliliters containing 1 gram of dose, obtains obtained liquid;Circulation Steam sterilizing is obtained final product makes oral liquid formulations.
Preparation method two
Step one, by 25 parts of asafoetide, 20 parts of kuh-seng, 20 parts of common embelia fruit, Qinghai iris 20 parts, 25 parts of bush, clearvers 25 parts, 20 parts of radix semiaquilegiae, 25 parts of alpine gentian, 25 parts of part, mao lotus dish of Tang Gute ultramarine 20, process 20 parts of radix bupleuri, 25 parts of root tuber of aromatic turmeric, trifoliate orange 20 parts of shell, 15 parts of fermented Chinese gall herb and tea leaves, 25 parts of Levant Cotton Root, 20 parts of safflower, 25 parts of Chinese Incarvilla Herb, 20 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is One gram, stirring, mixing in input mixer;
Step 2, be re-fed in pulverizer crush, the Chinese medicine composition after crushing is fitted in multi-function extractor, addition Relative to 8 times of water measured of its quality, boil 3 hours, steam pressure is 0.6Mpa process, filters, and obtains the first filtered fluid and filter Slag;
Step 3, the filter residue of acquisition is added again water relative to 6 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, is filtrated to get the second filtered fluid and filter residue;First filtered fluid and the second filtered fluid are merged, concentration removes moisture and obtains Get dry extract;
Step 4, crushed using super-fine powder mill, be crushed to below 30-50 microns acquisition Chinese medicine micropowders preparation, put Enter sealing in vessel standby.
Preparation method three
Step one, by 25 parts of asafoetide, 20 parts of kuh-seng, 20 parts of common embelia fruit, Qinghai iris 20 parts, 25 parts of bush, clearvers 25 parts, 20 parts of radix semiaquilegiae, 25 parts of alpine gentian, 25 parts of part, mao lotus dish of Tang Gute ultramarine 20, process 20 parts of radix bupleuri, 25 parts of root tuber of aromatic turmeric, trifoliate orange 20 parts of shell, 15 parts of fermented Chinese gall herb and tea leaves, 25 parts of Levant Cotton Root, 20 parts of safflower, 25 parts of Chinese Incarvilla Herb, 20 parts of Radix Glycyrrhizae (processed with honey), are well mixed, per part of original Medicine quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, is decocted 3 hours, and add water for the second time 6 times of weight, decocts 2 Hour;
Step 2, decoction liquor are filtered and obtain filtrate, and filtrate is concentrated into the clear cream that relative density is 1.23-1.33 (65 DEG C);
Mix in step 3, clear cream plus after appropriate amount of starch, be dried, crush, plus appropriate amount of ethanol is made and be dried after particle, it is whole Grain, obtains final product composition grain preparation.
The usage and dosage of Chinese medicine composition of the present invention:1st, pulvis, usage and dosage:It is for oral administration, by pig body weight 2g/kg dosage, often Day 1 time, be used in conjunction 8-10 days.2nd, oral liquid, usage and dosage:For oral administration, by pig body weight 3ml/kg dosage, one time a day, is used in conjunction 8-10 My god.3rd, granule, usage and dosage:For oral administration, by pig body weight 2g/kg dosage, one time a day, is used in conjunction 8-10 days.Or according to this enforcement The Chinese medicine preparation of example directly soaks Chinese medicine composition mixing, then carries out infusion and obtains traditional Chinese herbal decoction, according to the body weight of sick pig Choose appropriate decoction and directly sick pig is gavaged daily one, be used in conjunction 8-10 days.
Preferred embodiment 3
The Chinese medicine composition of the treatment Sarcocystis miescheriana disease of present embodiment, is constituted by following weight portion:9 parts of asafoetide, hardship 7 parts of ginseng, 6 parts of common embelia fruit, 7 parts of Qinghai iris, 8 parts of bush, 10 parts of clearvers, 7 parts of radix semiaquilegiae, 11 parts of alpine gentian, Tang are ancient 9 parts of part, mao lotus dish of special ultramarine 7, process 8 parts of radix bupleuri, 11 parts of root tuber of aromatic turmeric, 10 parts of Fructus Aurantii, 5 parts of fermented Chinese gall herb and tea leaves, 7 parts of Levant Cotton Root, safflower 6 Part, 10 parts of Chinese Incarvilla Herb, 10 parts of Radix Glycyrrhizae (processed with honey).
Preparation method one
Step one, by 9 parts of asafoetide, 7 parts of kuh-seng, 6 parts of common embelia fruit, Qinghai iris 7 parts, 8 parts of bush, 10 parts of clearvers, 7 parts of radix semiaquilegiae, 11 parts of alpine gentian, 9 parts of part, mao lotus dish of Tang Gute ultramarine 7, process 8 parts of radix bupleuri, 11 parts of root tuber of aromatic turmeric, 10 parts of Fructus Aurantii, hundred Medicine decoct 5 parts, 7 parts of Levant Cotton Root, 6 parts of safflower, 10 parts of Chinese Incarvilla Herb, 10 parts of Radix Glycyrrhizae (processed with honey) be well mixed, every part of active compound quality is one gram, Plus the distilled water immersion of 5 times of Chinese medicine gross weight is after 24 hours, decoct 3 times, maintain 0.5 hour after boiling every time, collecting decoction is simultaneously It is concentrated into thick shape concentrate;
Step 2, in concentrate plus concentration is that 95% ethanol is adjusted to determining alcohol for 20%, be sufficiently stirred for mixing, stand and sink Form sediment 24 hours, filter, filtrate recycling ethanol, reclaim the liquid after ethanol and add the ethanol that concentration is 95% to be adjusted to determining alcohol again to be 30%, stir evenly, staticly settle 48 hours, filter, filtrate recycling ethanol is further concentrated to without alcohol taste, the dosing in the liquid after concentration - 4 DEG C of refrigerations of 0 DEG C of amount distilled water of 4 times of liquid, staticly settle 48 hours;
Step 3, filtration obtain filtrate, and filtrate is concentrated into per 1.5 milliliters containing 1 gram of dose, obtains obtained liquid;Circulation Steam sterilizing is obtained final product makes oral liquid formulations.
Preparation method two
Step one, by 9 parts of asafoetide, 7 parts of kuh-seng, 6 parts of common embelia fruit, Qinghai iris 7 parts, 8 parts of bush, 10 parts of clearvers, 7 parts of radix semiaquilegiae, 11 parts of alpine gentian, 9 parts of part, mao lotus dish of Tang Gute ultramarine 7, process 8 parts of radix bupleuri, 11 parts of root tuber of aromatic turmeric, 10 parts of Fructus Aurantii, hundred Medicine decoct 5 parts, 7 parts of Levant Cotton Root, 6 parts of safflower, 10 parts of Chinese Incarvilla Herb, 10 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, input stirring Stirring, mixing in machine;
Step 2, be re-fed in pulverizer crush, the Chinese medicine composition after crushing is fitted in multi-function extractor, addition Relative to 8 times of water measured of its quality, boil 3 hours, steam pressure is 0.6Mpa process, filters, and obtains the first filtered fluid and filter Slag;
Step 3, the filter residue of acquisition is added again water relative to 6 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, is filtrated to get the second filtered fluid and filter residue;First filtered fluid and the second filtered fluid are merged, concentration removes moisture and obtains Get dry extract;
Step 4, crushed using super-fine powder mill, be crushed to below 30-50 microns acquisition Chinese medicine micropowders preparation, put Enter sealing in vessel standby.
Preparation method three
Step one, by 9 parts of asafoetide, 7 parts of kuh-seng, 6 parts of common embelia fruit, Qinghai iris 7 parts, 8 parts of bush, 10 parts of clearvers, 7 parts of radix semiaquilegiae, 11 parts of alpine gentian, 9 parts of part, mao lotus dish of Tang Gute ultramarine 7, process 8 parts of radix bupleuri, 11 parts of root tuber of aromatic turmeric, 10 parts of Fructus Aurantii, hundred Medicine decoct 5 parts, 7 parts of Levant Cotton Root, 6 parts of safflower, 10 parts of Chinese Incarvilla Herb, 10 parts of Radix Glycyrrhizae (processed with honey), be well mixed, every part of active compound quality is one Gram, medicine gross weight is designated as portion, and add water 8 times of weight, decocts 3 hours, and add water for the second time 6 times of weight, decocts 2 hours;
Step 2, decoction liquor are filtered and obtain filtrate, and filtrate is concentrated into the clear cream that relative density is 1.23-1.33 (65 DEG C);
Mix in step 3, clear cream plus after appropriate amount of starch, be dried, crush, plus appropriate amount of ethanol is made and be dried after particle, it is whole Grain, obtains final product composition grain preparation.
The usage and dosage of Chinese medicine composition of the present invention:1st, pulvis, usage and dosage:It is for oral administration, by pig body weight 2g/kg dosage, often Day 1 time, be used in conjunction 8-10 days.2nd, oral liquid, usage and dosage:For oral administration, by pig body weight 3ml/kg dosage, one time a day, is used in conjunction 8-10 My god.3rd, granule, usage and dosage:For oral administration, by pig body weight 2g/kg dosage, one time a day, is used in conjunction 8-10 days.Or according to this enforcement The Chinese medicine preparation of example directly soaks Chinese medicine composition mixing, then carries out infusion and obtains traditional Chinese herbal decoction, according to the body weight of sick pig Choose appropriate decoction and directly sick pig is gavaged daily one, be used in conjunction 8-10 days.
Preferred embodiment 4
The Chinese medicine composition of the treatment Sarcocystis miescheriana disease of present embodiment, is constituted by following weight portion:11 parts of asafoetide, hardship 9 parts of ginseng, 8 parts of common embelia fruit, 9 parts of Qinghai iris, 10 parts of bush, 12 parts of clearvers, 9 parts of radix semiaquilegiae, 13 parts of alpine gentian, Tang are ancient 11 parts of part, mao lotus dish of special ultramarine 9, process 10 parts of radix bupleuri, 13 parts of root tuber of aromatic turmeric, 12 parts of Fructus Aurantii, 7 parts of fermented Chinese gall herb and tea leaves, 9 parts of Levant Cotton Root, safflower 8 Part, 12 parts of Chinese Incarvilla Herb, 12 parts of Radix Glycyrrhizae (processed with honey).
Preparation method one
Step one, by 11 parts of asafoetide, 9 parts of kuh-seng, 8 parts of common embelia fruit, Qinghai iris 9 parts, 10 parts of bush, clearvers 12 Part, 9 parts of radix semiaquilegiae, 13 parts of alpine gentian, 11 parts of part, mao lotus dish of Tang Gute ultramarine 9, process 10 parts of radix bupleuri, 13 parts of root tuber of aromatic turmeric, Fructus Aurantii 12 Part, 7 parts of fermented Chinese gall herb and tea leaves, 9 parts of Levant Cotton Root, 8 parts of safflower, 12 parts of Chinese Incarvilla Herb, 12 parts of Radix Glycyrrhizae (processed with honey) are well mixed, and every part of active compound quality is One gram, plus the distilled water immersion of 5 times of Chinese medicine gross weight is after 24 hours, decocts 3 times, maintains 0.5 hour after boiling every time, merges and decocts Liquid is simultaneously concentrated into thick shape concentrate;
Step 2, in concentrate plus concentration is that 95% ethanol is adjusted to determining alcohol for 20%, be sufficiently stirred for mixing, stand and sink Form sediment 24 hours, filter, filtrate recycling ethanol, reclaim the liquid after ethanol and add the ethanol that concentration is 95% to be adjusted to determining alcohol again to be 30%, stir evenly, staticly settle 48 hours, filter, filtrate recycling ethanol is further concentrated to without alcohol taste, the dosing in the liquid after concentration - 4 DEG C of refrigerations of 0 DEG C of amount distilled water of 4 times of liquid, staticly settle 48 hours;
Step 3, filtration obtain filtrate, and filtrate is concentrated into per 1.5 milliliters containing 1 gram of dose, obtains obtained liquid;Circulation Steam sterilizing is obtained final product makes oral liquid formulations.
Preparation method two
Step one, by 11 parts of asafoetide, 9 parts of kuh-seng, 8 parts of common embelia fruit, Qinghai iris 9 parts, 10 parts of bush, clearvers 12 Part, 9 parts of radix semiaquilegiae, 13 parts of alpine gentian, 11 parts of part, mao lotus dish of Tang Gute ultramarine 9, process 10 parts of radix bupleuri, 13 parts of root tuber of aromatic turmeric, Fructus Aurantii 12 Part, 7 parts of fermented Chinese gall herb and tea leaves, 9 parts of Levant Cotton Root, 8 parts of safflower, 12 parts of Chinese Incarvilla Herb, 12 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one gram, is thrown Enter stirring in mixer, mixing;
Step 2, be re-fed in pulverizer crush, the Chinese medicine composition after crushing is fitted in multi-function extractor, addition Relative to 8 times of water measured of its quality, boil 3 hours, steam pressure is 0.6Mpa process, filters, and obtains the first filtered fluid and filter Slag;
Step 3, the filter residue of acquisition is added again water relative to 6 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, is filtrated to get the second filtered fluid and filter residue;First filtered fluid and the second filtered fluid are merged, concentration removes moisture and obtains Get dry extract;
Step 4, crushed using super-fine powder mill, be crushed to below 30-50 microns acquisition Chinese medicine micropowders preparation, put Enter sealing in vessel standby.
Preparation method three
Step one, by 11 parts of asafoetide, 9 parts of kuh-seng, 8 parts of common embelia fruit, Qinghai iris 9 parts, 10 parts of bush, clearvers 12 Part, 9 parts of radix semiaquilegiae, 13 parts of alpine gentian, 11 parts of part, mao lotus dish of Tang Gute ultramarine 9, process 10 parts of radix bupleuri, 13 parts of root tuber of aromatic turmeric, Fructus Aurantii 12 Part, 7 parts of fermented Chinese gall herb and tea leaves, 9 parts of Levant Cotton Root, 8 parts of safflower, 12 parts of Chinese Incarvilla Herb, 12 parts of Radix Glycyrrhizae (processed with honey), are well mixed, every part of active compound quality For one gram, medicine gross weight is designated as portion, and add water 8 times of weight, decocts 3 hours, and add water for the second time 6 times of weight, decocts 2 hours;
Step 2, decoction liquor are filtered and obtain filtrate, and filtrate is concentrated into the clear cream that relative density is 1.23-1.33 (65 DEG C);
Mix in step 3, clear cream plus after appropriate amount of starch, be dried, crush, plus appropriate amount of ethanol is made and be dried after particle, it is whole Grain, obtains final product composition grain preparation.
The usage and dosage of Chinese medicine composition of the present invention:1st, pulvis, usage and dosage:It is for oral administration, by pig body weight 2g/kg dosage, often Day 1 time, be used in conjunction 8-10 days.2nd, oral liquid, usage and dosage:For oral administration, by pig body weight 3ml/kg dosage, one time a day, is used in conjunction 8-10 My god.3rd, granule, usage and dosage:For oral administration, by pig body weight 2g/kg dosage, one time a day, is used in conjunction 8-10 days.Or according to this enforcement The Chinese medicine preparation of example directly soaks Chinese medicine composition mixing, then carries out infusion and obtains traditional Chinese herbal decoction, according to the body weight of sick pig Choose appropriate decoction and directly sick pig is gavaged daily one, be used in conjunction 8-10 days.
Preferred embodiment 5
The Chinese medicine composition of the treatment Sarcocystis miescheriana disease of present embodiment, is constituted by following weight portion:13 parts of asafoetide, hardship Ginseng 11 parts, 10 parts of common embelia fruit, Qinghai iris 12 parts, 12 parts of bush, 14 parts of clearvers, 11 parts of radix semiaquilegiae, 15 parts of alpine gentian, 13 parts of part, mao lotus dish of Tang Gute ultramarine 14, process 12 parts of radix bupleuri, 15 parts of root tuber of aromatic turmeric, 14 parts of Fructus Aurantii, 9 parts of fermented Chinese gall herb and tea leaves, 12 parts of Levant Cotton Root, 10 parts of safflower, 14 parts of Chinese Incarvilla Herb, 14 parts of Radix Glycyrrhizae (processed with honey).
Preparation method one
Step one, by 13 parts of asafoetide, 11 parts of kuh-seng, 10 parts of common embelia fruit, Qinghai iris 12 parts, 12 parts of bush, clearvers 14 parts, 11 parts of radix semiaquilegiae, 15 parts of alpine gentian, 13 parts of part, mao lotus dish of Tang Gute ultramarine 14, process 12 parts of radix bupleuri, 15 parts of root tuber of aromatic turmeric, trifoliate orange 14 parts of shell, 9 parts of fermented Chinese gall herb and tea leaves, 12 parts of Levant Cotton Root, 10 parts of safflower, 14 parts of Chinese Incarvilla Herb, 14 parts of Radix Glycyrrhizae (processed with honey) are well mixed, every part of active compound Quality is one gram, plus the distilled water immersion of 5 times of Chinese medicine gross weight is after 24 hours, is decocted 3 times, is maintained 0.5 hour after boiling every time, Collecting decoction is simultaneously concentrated into thick shape concentrate;
Step 2, in concentrate plus concentration is that 95% ethanol is adjusted to determining alcohol for 20%, be sufficiently stirred for mixing, stand and sink Form sediment 24 hours, filter, filtrate recycling ethanol, reclaim the liquid after ethanol and add the ethanol that concentration is 95% to be adjusted to determining alcohol again to be 30%, stir evenly, staticly settle 48 hours, filter, filtrate recycling ethanol is further concentrated to without alcohol taste, the dosing in the liquid after concentration - 4 DEG C of refrigerations of 0 DEG C of amount distilled water of 4 times of liquid, staticly settle 48 hours;
Step 3, filtration obtain filtrate, and filtrate is concentrated into per 1.5 milliliters containing 1 gram of dose, obtains obtained liquid;Circulation Steam sterilizing is obtained final product makes oral liquid formulations.
Preparation method two
Step one, by 13 parts of asafoetide, 11 parts of kuh-seng, 10 parts of common embelia fruit, Qinghai iris 12 parts, 12 parts of bush, clearvers 14 parts, 11 parts of radix semiaquilegiae, 15 parts of alpine gentian, 13 parts of part, mao lotus dish of Tang Gute ultramarine 14, process 12 parts of radix bupleuri, 15 parts of root tuber of aromatic turmeric, trifoliate orange 14 parts of shell, 9 parts of fermented Chinese gall herb and tea leaves, 12 parts of Levant Cotton Root, 10 parts of safflower, 14 parts of Chinese Incarvilla Herb, 14 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is one Gram, stirring, mixing in input mixer;
Step 2, be re-fed in pulverizer crush, the Chinese medicine composition after crushing is fitted in multi-function extractor, addition Relative to 8 times of water measured of its quality, boil 3 hours, steam pressure is 0.6Mpa process, filters, and obtains the first filtered fluid and filter Slag;
Step 3, the filter residue of acquisition is added again water relative to 6 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, is filtrated to get the second filtered fluid and filter residue;First filtered fluid and the second filtered fluid are merged, concentration removes moisture and obtains Get dry extract;
Step 4, crushed using super-fine powder mill, be crushed to below 30-50 microns acquisition Chinese medicine micropowders preparation, put Enter sealing in vessel standby.
Preparation method three
Step one, by 13 parts of asafoetide, 11 parts of kuh-seng, 10 parts of common embelia fruit, Qinghai iris 12 parts, 12 parts of bush, clearvers 14 parts, 11 parts of radix semiaquilegiae, 15 parts of alpine gentian, 13 parts of part, mao lotus dish of Tang Gute ultramarine 14, process 12 parts of radix bupleuri, 15 parts of root tuber of aromatic turmeric, trifoliate orange 14 parts of shell, 9 parts of fermented Chinese gall herb and tea leaves, 12 parts of Levant Cotton Root, 10 parts of safflower, 14 parts of Chinese Incarvilla Herb, 14 parts of Radix Glycyrrhizae (processed with honey), are well mixed, per part of original Medicine quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, is decocted 3 hours, and add water for the second time 6 times of weight, decocts 2 Hour;
Step 2, decoction liquor are filtered and obtain filtrate, and filtrate is concentrated into the clear cream that relative density is 1.23-1.33 (65 DEG C);
Mix in step 3, clear cream plus after appropriate amount of starch, be dried, crush, plus appropriate amount of ethanol is made and be dried after particle, it is whole Grain, obtains final product composition grain preparation.
The usage and dosage of Chinese medicine composition of the present invention:1st, pulvis, usage and dosage:It is for oral administration, by pig body weight 2g/kg dosage, often Day 1 time, be used in conjunction 8-10 days.2nd, oral liquid, usage and dosage:For oral administration, by pig body weight 3ml/kg dosage, one time a day, is used in conjunction 8-10 My god.3rd, granule, usage and dosage:For oral administration, by pig body weight 2g/kg dosage, one time a day, is used in conjunction 8-10 days.Or according to this enforcement The Chinese medicine preparation of example directly soaks Chinese medicine composition mixing, then carries out infusion and obtains traditional Chinese herbal decoction, according to the body weight of sick pig Choose appropriate decoction and directly sick pig is gavaged daily one, be used in conjunction 8-10 days.
Preferred embodiment 6
The Chinese medicine composition of the treatment Sarcocystis miescheriana disease of present embodiment, is constituted by following weight portion:16 parts of asafoetide, hardship Ginseng 13 parts, 12 parts of common embelia fruit, Qinghai iris 14 parts, 15 parts of bush, 16 parts of clearvers, 13 parts of radix semiaquilegiae, 17 parts of alpine gentian, 15 parts of part, mao lotus dish of Tang Gute ultramarine 16, process 14 parts of radix bupleuri, 17 parts of root tuber of aromatic turmeric, 16 parts of Fructus Aurantii, 12 parts of fermented Chinese gall herb and tea leaves, 15 parts of Levant Cotton Root, 12 parts of safflower, 16 parts of Chinese Incarvilla Herb, 16 parts of Radix Glycyrrhizae (processed with honey).
Preparation method one
Step one, by 16 parts of asafoetide, 13 parts of kuh-seng, 12 parts of common embelia fruit, Qinghai iris 14 parts, 15 parts of bush, clearvers 16 parts, 13 parts of radix semiaquilegiae, 17 parts of alpine gentian, 15 parts of part, mao lotus dish of Tang Gute ultramarine 16, process 14 parts of radix bupleuri, 17 parts of root tuber of aromatic turmeric, trifoliate orange 16 parts of shell, 12 parts of fermented Chinese gall herb and tea leaves, 15 parts of Levant Cotton Root, 12 parts of safflower, 16 parts of Chinese Incarvilla Herb, 16 parts of Radix Glycyrrhizae (processed with honey) are well mixed, per part of original Medicine quality is one gram, plus the distilled water immersion of 5 times of Chinese medicine gross weight is after 24 hours, is decocted 3 times, and maintenance 0.5 is little after boiling every time When, collecting decoction is simultaneously concentrated into thick shape concentrate;
Step 2, in concentrate plus concentration is that 95% ethanol is adjusted to determining alcohol for 20%, be sufficiently stirred for mixing, stand and sink Form sediment 24 hours, filter, filtrate recycling ethanol, reclaim the liquid after ethanol and add the ethanol that concentration is 95% to be adjusted to determining alcohol again to be 30%, stir evenly, staticly settle 48 hours, filter, filtrate recycling ethanol is further concentrated to without alcohol taste, the dosing in the liquid after concentration - 4 DEG C of refrigerations of 0 DEG C of amount distilled water of 4 times of liquid, staticly settle 48 hours;
Step 3, filtration obtain filtrate, and filtrate is concentrated into per 1.5 milliliters containing 1 gram of dose, obtains obtained liquid;Circulation Steam sterilizing is obtained final product makes oral liquid formulations.
Preparation method two
Step one, by 16 parts of asafoetide, 13 parts of kuh-seng, 12 parts of common embelia fruit, Qinghai iris 14 parts, 15 parts of bush, clearvers 16 parts, 13 parts of radix semiaquilegiae, 17 parts of alpine gentian, 15 parts of part, mao lotus dish of Tang Gute ultramarine 16, process 14 parts of radix bupleuri, 17 parts of root tuber of aromatic turmeric, trifoliate orange 16 parts of shell, 12 parts of fermented Chinese gall herb and tea leaves, 15 parts of Levant Cotton Root, 12 parts of safflower, 16 parts of Chinese Incarvilla Herb, 16 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is One gram, stirring, mixing in input mixer;
Step 2, be re-fed in pulverizer crush, the Chinese medicine composition after crushing is fitted in multi-function extractor, addition Relative to 8 times of water measured of its quality, boil 3 hours, steam pressure is 0.6Mpa process, filters, and obtains the first filtered fluid and filter Slag;
Step 3, the filter residue of acquisition is added again water relative to 6 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, is filtrated to get the second filtered fluid and filter residue;First filtered fluid and the second filtered fluid are merged, concentration removes moisture and obtains Get dry extract;
Step 4, crushed using super-fine powder mill, be crushed to below 30-50 microns acquisition Chinese medicine micropowders preparation, put Enter sealing in vessel standby.
Preparation method three
Step one, by 16 parts of asafoetide, 13 parts of kuh-seng, 12 parts of common embelia fruit, Qinghai iris 14 parts, 15 parts of bush, clearvers 16 parts, 13 parts of radix semiaquilegiae, 17 parts of alpine gentian, 15 parts of part, mao lotus dish of Tang Gute ultramarine 16, process 14 parts of radix bupleuri, 17 parts of root tuber of aromatic turmeric, trifoliate orange 16 parts of shell, 12 parts of fermented Chinese gall herb and tea leaves, 15 parts of Levant Cotton Root, 12 parts of safflower, 16 parts of Chinese Incarvilla Herb, 16 parts of Radix Glycyrrhizae (processed with honey), are well mixed, per part of original Medicine quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, is decocted 3 hours, and add water for the second time 6 times of weight, decocts 2 Hour;
Step 2, decoction liquor are filtered and obtain filtrate, and filtrate is concentrated into the clear cream that relative density is 1.23-1.33 (65 DEG C);
Mix in step 3, clear cream plus after appropriate amount of starch, be dried, crush, plus appropriate amount of ethanol is made and be dried after particle, it is whole Grain, obtains final product composition grain preparation.
The usage and dosage of Chinese medicine composition of the present invention:1st, pulvis, usage and dosage:It is for oral administration, by pig body weight 2g/kg dosage, often Day 1 time, be used in conjunction 8-10 days.2nd, oral liquid, usage and dosage:For oral administration, by pig body weight 3ml/kg dosage, one time a day, is used in conjunction 8-10 My god.3rd, granule, usage and dosage:For oral administration, by pig body weight 2g/kg dosage, one time a day, is used in conjunction 8-10 days.Or according to this enforcement The Chinese medicine preparation of example directly soaks Chinese medicine composition mixing, then carries out infusion and obtains traditional Chinese herbal decoction, according to the body weight of sick pig Choose appropriate decoction and directly sick pig is gavaged daily one, be used in conjunction 8-10 days.
Preferred embodiment 7
The Chinese medicine composition of the treatment Sarcocystis miescheriana disease of present embodiment, is constituted by following weight portion:19 parts of asafoetide, hardship Ginseng 15 parts, 14 parts of common embelia fruit, Qinghai iris 14 parts, 18 parts of bush, 18 parts of clearvers, 16 parts of radix semiaquilegiae, 20 parts of alpine gentian, 17 parts of part, mao lotus dish of Tang Gute ultramarine 18, process 16 parts of radix bupleuri, 19 parts of root tuber of aromatic turmeric, 18 parts of Fructus Aurantii, 14 parts of fermented Chinese gall herb and tea leaves, 17 parts of Levant Cotton Root, 14 parts of safflower, 18 parts of Chinese Incarvilla Herb, 17 parts of Radix Glycyrrhizae (processed with honey).
Preparation method one
Step one, by 19 parts of asafoetide, 15 parts of kuh-seng, 14 parts of common embelia fruit, Qinghai iris 14 parts, 18 parts of bush, clearvers 18 parts, 16 parts of radix semiaquilegiae, 20 parts of alpine gentian, 17 parts of part, mao lotus dish of Tang Gute ultramarine 18, process 16 parts of radix bupleuri, 19 parts of root tuber of aromatic turmeric, trifoliate orange 18 parts of shell, 14 parts of fermented Chinese gall herb and tea leaves, 17 parts of Levant Cotton Root, 14 parts of safflower, 18 parts of Chinese Incarvilla Herb, 17 parts of Radix Glycyrrhizae (processed with honey) are well mixed, per part of original Medicine quality is one gram, plus the distilled water immersion of 5 times of Chinese medicine gross weight is after 24 hours, is decocted 3 times, and maintenance 0.5 is little after boiling every time When, collecting decoction is simultaneously concentrated into thick shape concentrate;
Step 2, in concentrate plus concentration is that 95% ethanol is adjusted to determining alcohol for 20%, be sufficiently stirred for mixing, stand and sink Form sediment 24 hours, filter, filtrate recycling ethanol, reclaim the liquid after ethanol and add the ethanol that concentration is 95% to be adjusted to determining alcohol again to be 30%, stir evenly, staticly settle 48 hours, filter, filtrate recycling ethanol is further concentrated to without alcohol taste, the dosing in the liquid after concentration - 4 DEG C of refrigerations of 0 DEG C of amount distilled water of 4 times of liquid, staticly settle 48 hours;
Step 3, filtration obtain filtrate, and filtrate is concentrated into per 1.5 milliliters containing 1 gram of dose, obtains obtained liquid;Circulation Steam sterilizing is obtained final product makes oral liquid formulations.
Preparation method two
Step one, by 19 parts of asafoetide, 15 parts of kuh-seng, 14 parts of common embelia fruit, Qinghai iris 14 parts, 18 parts of bush, clearvers 18 parts, 16 parts of radix semiaquilegiae, 20 parts of alpine gentian, 17 parts of part, mao lotus dish of Tang Gute ultramarine 18, process 16 parts of radix bupleuri, 19 parts of root tuber of aromatic turmeric, trifoliate orange 18 parts of shell, 14 parts of fermented Chinese gall herb and tea leaves, 17 parts of Levant Cotton Root, 14 parts of safflower, 18 parts of Chinese Incarvilla Herb, 17 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is One gram, stirring, mixing in input mixer;
Step 2, be re-fed in pulverizer crush, the Chinese medicine composition after crushing is fitted in multi-function extractor, addition Relative to 8 times of water measured of its quality, boil 3 hours, steam pressure is 0.6Mpa process, filters, and obtains the first filtered fluid and filter Slag;
Step 3, the filter residue of acquisition is added again water relative to 6 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, is filtrated to get the second filtered fluid and filter residue;First filtered fluid and the second filtered fluid are merged, concentration removes moisture and obtains Get dry extract;
Step 4, crushed using super-fine powder mill, be crushed to below 30-50 microns acquisition Chinese medicine micropowders preparation, put Enter sealing in vessel standby.
Preparation method three
Step one, by 19 parts of asafoetide, 15 parts of kuh-seng, 14 parts of common embelia fruit, Qinghai iris 14 parts, 18 parts of bush, clearvers 18 parts, 16 parts of radix semiaquilegiae, 20 parts of alpine gentian, 17 parts of part, mao lotus dish of Tang Gute ultramarine 18, process 16 parts of radix bupleuri, 19 parts of root tuber of aromatic turmeric, trifoliate orange 18 parts of shell, 14 parts of fermented Chinese gall herb and tea leaves, 17 parts of Levant Cotton Root, 14 parts of safflower, 18 parts of Chinese Incarvilla Herb, 17 parts of Radix Glycyrrhizae (processed with honey), are well mixed, per part of original Medicine quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, is decocted 3 hours, and add water for the second time 6 times of weight, decocts 2 Hour;
Step 2, decoction liquor are filtered and obtain filtrate, and filtrate is concentrated into the clear cream that relative density is 1.23-1.33 (65 DEG C);
Mix in step 3, clear cream plus after appropriate amount of starch, be dried, crush, plus appropriate amount of ethanol is made and be dried after particle, it is whole Grain, obtains final product composition grain preparation.
The usage and dosage of Chinese medicine composition of the present invention:1st, pulvis, usage and dosage:It is for oral administration, by pig body weight 2g/kg dosage, often Day 1 time, be used in conjunction 8-10 days.2nd, oral liquid, usage and dosage:For oral administration, by pig body weight 3ml/kg dosage, one time a day, is used in conjunction 8-10 My god.3rd, granule, usage and dosage:For oral administration, by pig body weight 2g/kg dosage, one time a day, is used in conjunction 8-10 days.Or according to this enforcement The Chinese medicine preparation of example directly soaks Chinese medicine composition mixing, then carries out infusion and obtains traditional Chinese herbal decoction, according to the body weight of sick pig Choose appropriate decoction and directly sick pig is gavaged daily one, be used in conjunction 8-10 days.
Preferred embodiment 8
The Chinese medicine composition of the treatment Sarcocystis miescheriana disease of present embodiment, is constituted by following weight portion:22 parts of asafoetide, hardship Ginseng 17 parts, 16 parts of common embelia fruit, Qinghai iris 16 parts, 20 parts of bush, 20 parts of clearvers, 19 parts of radix semiaquilegiae, 22 parts of alpine gentian, 20 parts of part, mao lotus dish of Tang Gute ultramarine 19, process 18 parts of radix bupleuri, 21 parts of root tuber of aromatic turmeric, 19 parts of Fructus Aurantii, 11 parts of fermented Chinese gall herb and tea leaves, 20 parts of Levant Cotton Root, 16 parts of safflower, 20 parts of Chinese Incarvilla Herb, 18 parts of Radix Glycyrrhizae (processed with honey).
Preparation method one
Step one, by 22 parts of asafoetide, 17 parts of kuh-seng, 16 parts of common embelia fruit, Qinghai iris 16 parts, 20 parts of bush, clearvers 20 parts, 19 parts of radix semiaquilegiae, 22 parts of alpine gentian, 20 parts of part, mao lotus dish of Tang Gute ultramarine 19, process 18 parts of radix bupleuri, 21 parts of root tuber of aromatic turmeric, trifoliate orange 19 parts of shell, 11 parts of fermented Chinese gall herb and tea leaves, 20 parts of Levant Cotton Root, 16 parts of safflower, 20 parts of Chinese Incarvilla Herb, 18 parts of Radix Glycyrrhizae (processed with honey) are well mixed, per part of original Medicine quality is one gram, plus the distilled water immersion of 5 times of Chinese medicine gross weight is after 24 hours, is decocted 3 times, and maintenance 0.5 is little after boiling every time When, collecting decoction is simultaneously concentrated into thick shape concentrate;
Step 2, in concentrate plus concentration is that 95% ethanol is adjusted to determining alcohol for 20%, be sufficiently stirred for mixing, stand and sink Form sediment 24 hours, filter, filtrate recycling ethanol, reclaim the liquid after ethanol and add the ethanol that concentration is 95% to be adjusted to determining alcohol again to be 30%, stir evenly, staticly settle 48 hours, filter, filtrate recycling ethanol is further concentrated to without alcohol taste, the dosing in the liquid after concentration - 4 DEG C of refrigerations of 0 DEG C of amount distilled water of 4 times of liquid, staticly settle 48 hours;
Step 3, filtration obtain filtrate, and filtrate is concentrated into per 1.5 milliliters containing 1 gram of dose, obtains obtained liquid;Circulation Steam sterilizing is obtained final product makes oral liquid formulations.
Preparation method two
Step one, by 22 parts of asafoetide, 17 parts of kuh-seng, 16 parts of common embelia fruit, Qinghai iris 16 parts, 20 parts of bush, clearvers 20 parts, 19 parts of radix semiaquilegiae, 22 parts of alpine gentian, 20 parts of part, mao lotus dish of Tang Gute ultramarine 19, process 18 parts of radix bupleuri, 21 parts of root tuber of aromatic turmeric, trifoliate orange 19 parts of shell, 11 parts of fermented Chinese gall herb and tea leaves, 20 parts of Levant Cotton Root, 16 parts of safflower, 20 parts of Chinese Incarvilla Herb, 18 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is One gram, stirring, mixing in input mixer;
Step 2, be re-fed in pulverizer crush, the Chinese medicine composition after crushing is fitted in multi-function extractor, addition Relative to 8 times of water measured of its quality, boil 3 hours, steam pressure is 0.6Mpa process, filters, and obtains the first filtered fluid and filter Slag;
Step 3, the filter residue of acquisition is added again water relative to 6 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, is filtrated to get the second filtered fluid and filter residue;First filtered fluid and the second filtered fluid are merged, concentration removes moisture and obtains Get dry extract;
Step 4, crushed using super-fine powder mill, be crushed to below 30-50 microns acquisition Chinese medicine micropowders preparation, put Enter sealing in vessel standby.
Preparation method three
Step one, by 22 parts of asafoetide, 17 parts of kuh-seng, 16 parts of common embelia fruit, Qinghai iris 16 parts, 20 parts of bush, clearvers 20 parts, 19 parts of radix semiaquilegiae, 22 parts of alpine gentian, 20 parts of part, mao lotus dish of Tang Gute ultramarine 19, process 18 parts of radix bupleuri, 21 parts of root tuber of aromatic turmeric, trifoliate orange 19 parts of shell, 11 parts of fermented Chinese gall herb and tea leaves, 20 parts of Levant Cotton Root, 16 parts of safflower, 20 parts of Chinese Incarvilla Herb, 18 parts of Radix Glycyrrhizae (processed with honey), are well mixed, per part of original Medicine quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, is decocted 3 hours, and add water for the second time 6 times of weight, decocts 2 Hour;
Step 2, decoction liquor are filtered and obtain filtrate, and filtrate is concentrated into the clear cream that relative density is 1.23-1.33 (65 DEG C);
Mix in step 3, clear cream plus after appropriate amount of starch, be dried, crush, plus appropriate amount of ethanol is made and be dried after particle, it is whole Grain, obtains final product composition grain preparation.
The usage and dosage of Chinese medicine composition of the present invention:1st, pulvis, usage and dosage:It is for oral administration, by pig body weight 2g/kg dosage, often Day 1 time, be used in conjunction 8-10 days.2nd, oral liquid, usage and dosage:For oral administration, by pig body weight 3ml/kg dosage, one time a day, is used in conjunction 8-10 My god.3rd, granule, usage and dosage:For oral administration, by pig body weight 2g/kg dosage, one time a day, is used in conjunction 8-10 days.Or according to this enforcement The Chinese medicine preparation of example directly soaks Chinese medicine composition mixing, then carries out infusion and obtains traditional Chinese herbal decoction, according to the body weight of sick pig Choose appropriate decoction and directly sick pig is gavaged daily one, be used in conjunction 8-10 days.
Preferred embodiment 9
The Chinese medicine composition of the treatment Sarcocystis miescheriana disease of present embodiment, is constituted by following weight portion:24 parts of asafoetide, hardship Ginseng 19 parts, 18 parts of common embelia fruit, Qinghai iris 18 parts, 22 parts of bush, 23 parts of clearvers, 17 parts of radix semiaquilegiae, 24 parts of alpine gentian, 23 parts of part, mao lotus dish of Tang Gute ultramarine 17, process 19 parts of radix bupleuri, 23 parts of root tuber of aromatic turmeric, 16 parts of Fructus Aurantii, 13 parts of fermented Chinese gall herb and tea leaves, 23 parts of Levant Cotton Root, 18 parts of safflower, 22 parts of Chinese Incarvilla Herb, 19 parts of Radix Glycyrrhizae (processed with honey).
Preparation method one
Step one, by 24 parts of asafoetide, 19 parts of kuh-seng, 18 parts of common embelia fruit, Qinghai iris 18 parts, 22 parts of bush, clearvers 23 parts, 17 parts of radix semiaquilegiae, 24 parts of alpine gentian, 23 parts of part, mao lotus dish of Tang Gute ultramarine 17, process 19 parts of radix bupleuri, 23 parts of root tuber of aromatic turmeric, trifoliate orange 16 parts of shell, 13 parts of fermented Chinese gall herb and tea leaves, 23 parts of Levant Cotton Root, 18 parts of safflower, 22 parts of Chinese Incarvilla Herb, 19 parts of Radix Glycyrrhizae (processed with honey) are well mixed, per part of original Medicine quality is one gram, plus the distilled water immersion of 5 times of Chinese medicine gross weight is after 24 hours, is decocted 3 times, and maintenance 0.5 is little after boiling every time When, collecting decoction is simultaneously concentrated into thick shape concentrate;
Step 2, in concentrate plus concentration is that 95% ethanol is adjusted to determining alcohol for 20%, be sufficiently stirred for mixing, stand and sink Form sediment 24 hours, filter, filtrate recycling ethanol, reclaim the liquid after ethanol and add the ethanol that concentration is 95% to be adjusted to determining alcohol again to be 30%, stir evenly, staticly settle 48 hours, filter, filtrate recycling ethanol is further concentrated to without alcohol taste, the dosing in the liquid after concentration - 4 DEG C of refrigerations of 0 DEG C of amount distilled water of 4 times of liquid, staticly settle 48 hours;
Step 3, filtration obtain filtrate, and filtrate is concentrated into per 1.5 milliliters containing 1 gram of dose, obtains obtained liquid;Circulation Steam sterilizing is obtained final product makes oral liquid formulations.
Preparation method two
Step one, by 24 parts of asafoetide, 19 parts of kuh-seng, 18 parts of common embelia fruit, Qinghai iris 18 parts, 22 parts of bush, clearvers 23 parts, 17 parts of radix semiaquilegiae, 24 parts of alpine gentian, 23 parts of part, mao lotus dish of Tang Gute ultramarine 17, process 19 parts of radix bupleuri, 23 parts of root tuber of aromatic turmeric, trifoliate orange 16 parts of shell, 13 parts of fermented Chinese gall herb and tea leaves, 23 parts of Levant Cotton Root, 18 parts of safflower, 22 parts of Chinese Incarvilla Herb, 19 parts of Radix Glycyrrhizae (processed with honey), every part of active compound quality is One gram, stirring, mixing in input mixer;
Step 2, be re-fed in pulverizer crush, the Chinese medicine composition after crushing is fitted in multi-function extractor, addition Relative to 8 times of water measured of its quality, boil 3 hours, steam pressure is 0.6Mpa process, filters, and obtains the first filtered fluid and filter Slag;
Step 3, the filter residue of acquisition is added again water relative to 6 times of its quality amount, boil 2 hours, steam pressure be 1Mpa process, is filtrated to get the second filtered fluid and filter residue;First filtered fluid and the second filtered fluid are merged, concentration removes moisture and obtains Get dry extract;
Step 4, crushed using super-fine powder mill, be crushed to below 30-50 microns acquisition Chinese medicine micropowders preparation, put Enter sealing in vessel standby.
Preparation method three
Step one, by 24 parts of asafoetide, 19 parts of kuh-seng, 18 parts of common embelia fruit, Qinghai iris 18 parts, 22 parts of bush, clearvers 23 parts, 17 parts of radix semiaquilegiae, 24 parts of alpine gentian, 23 parts of part, mao lotus dish of Tang Gute ultramarine 17, process 19 parts of radix bupleuri, 23 parts of root tuber of aromatic turmeric, trifoliate orange 16 parts of shell, 13 parts of fermented Chinese gall herb and tea leaves, 23 parts of Levant Cotton Root, 18 parts of safflower, 22 parts of Chinese Incarvilla Herb, 19 parts of Radix Glycyrrhizae (processed with honey), are well mixed, per part of original Medicine quality is one gram, and medicine gross weight is designated as portion, and add water 8 times of weight, is decocted 3 hours, and add water for the second time 6 times of weight, decocts 2 Hour;
Step 2, decoction liquor are filtered and obtain filtrate, and filtrate is concentrated into the clear cream that relative density is 1.23-1.33 (65 DEG C);
Mix in step 3, clear cream plus after appropriate amount of starch, be dried, crush, plus appropriate amount of ethanol is made and be dried after particle, it is whole Grain, obtains final product composition grain preparation.
The usage and dosage of Chinese medicine composition of the present invention:1st, pulvis, usage and dosage:It is for oral administration, by pig body weight 2g/kg dosage, often Day 1 time, be used in conjunction 8-10 days.2nd, oral liquid, usage and dosage:For oral administration, by pig body weight 3ml/kg dosage, one time a day, is used in conjunction 8-10 My god.3rd, granule, usage and dosage:For oral administration, by pig body weight 2g/kg dosage, one time a day, is used in conjunction 8-10 days.Or according to this enforcement The Chinese medicine preparation of example directly soaks Chinese medicine composition mixing, then carries out infusion and obtains traditional Chinese herbal decoction, according to the body weight of sick pig Choose appropriate decoction and directly sick pig is gavaged daily one, be used in conjunction 8-10 days.
Concrete test
Experimental animal:Sarcocystis sick pig a group in clinical data, course of disease 30-45 days, age, body weight, body condition are close, tool There is comparativity, be randomly divided into 6 groups.Antigen indirect hemagglutination test is made with the slow raw bodies of S.cruzi, sick pig is surveyed and is eaten after sporangium When 30-45 days, sick pig serum titer is more than 1:162;Eat 90 days after sporangium, serum titer is up to 1:39000.According to test Sick pig serum titer is slightly larger than 1:162 numerical value, can go out the time of experimental group sick pig infection sarcocystis as 30-45 with budgetary estimate My god;It is divided into 6 test groups as test basis, 6 test group sick pig dye worm time is close, with comparativity;
Trial drug:Present composition test group medicine, the group for being prepared from preferred embodiment 1,2,6,8,9 respectively Compound pulvis, takes orally, and by pig body weight 2g/kg dosage, one time a day, is used in conjunction 8 days;
Control group choice of drug, salinomycin (commercially available prod, salinomycin pre-mixing agent, the salinomycin content of specification 24%) takes orally, By pig body weight 80mg/kg dosage, one time a day, is used in conjunction 8 days;
Test diagnosis method:1st, gather sick pig whole blood to separate after serum, indirect hemagglutination (IHA) detection test in Jing laboratories is surveyed Determine drug effect.2nd, zinc sulfate floatation method is used, sarcocystis egg capsule in sick pig excrement is checked, drug effect is determined;
1 composition test group of table and salinomycin control group contrast experiment
Test group Treatment Cure It is effective It is invalid
Test 1 group 14 12 13 1
Test 2 groups 15 14 14 1
Test 3 groups 13 13 11 2
Test 4 groups 15 12 13 2
Test 5 groups 12 11 12 0
Salinomycin group 13 11 12 1
Curative effect determinate standard:Cure:Body temperature is raised, anorexia recovers normal, and intermittence stomachache, diarrhoea disappear, collection Sick pig whole blood is separated after serum, and Jing indirect hemagglutination tests testing result is in total negative.It is effective:Hypothermia, feed intake increases, Intermittence stomachache, diarrhoea mitigate, and collection sick pig whole blood is separated after serum, and Jing indirect hemagglutination tests testing result is negative in part. It is invalid:Clinical symptoms have no any change, and collection sick pig whole blood is separated after serum, and Jing indirect hemagglutination tests testing result is in all It is positive.
Test case:Certain pig farm poultry raiser reacts, and this has in the recent period 5 mouthfuls of pig spirit depressed, anorexia, arranges athero- excrement Just, there is stomachache performance.
Clinical examination:Sick pig body temperature is increased to more than 40 DEG C, in interval heat type, breathes per minute 22-26/ time, sick pig food It is intended to go down, part sick pig has diarrhoea performance.
Diagnosis:Sick pig excrement zinc sulfate floatation method is combined according to clinical symptoms and check capsule ovum or sporangium, detect a small amount of capsule Ovum or sporangium, using laboratory indirect hemagglutination test, all positives of result of the test sick pig, are diagnosed as Sarcocystis miescheriana disease.
Treatment:From composition pulvis prepared by this preferred embodiment 3, all 5 stomatosis pigs are passed through to gavage administration, often It 1 time, it is used in conjunction 8 days;Sick pig temperature decline after medication 5 days, a small amount of drinking-water and takes food, and part sick pig diarrhoea number of times is reduced, gradually Dilute soft shaping excrement is arranged, sick pig intermittence colic symptoms substantially mitigate;Medication is examined after 15 days with Jing indirect hemagglutination (IHA)s test Result total negative is surveyed, follow-up poultry raiser reaction sick pig fully recovers, has no recurrence after January.

Claims (10)

1. it is a kind of to treat the sick Chinese medicine composition of Sarcocystis miescheriana, it is characterised in that to constitute by following weight portion:Asafoetide 8-25 Part, kuh-seng 6-20 parts, common embelia fruit 5-20 parts, the sub- 5-20 parts of Qinghai iris, bush 5-25 parts, clearvers 8-25 parts, radix semiaquilegiae 5- 20 parts, alpine gentian 9-25 parts, Tang Gute ultramarine 5-20 parts, hair lotus dish 8-25 parts, process radix bupleuri 6-20 parts, root tuber of aromatic turmeric 9-25 parts, trifoliate orange Shell 8-20 parts, fermented Chinese gall herb and tea leaves 3-15 parts, Levant Cotton Root 5-25 parts, safflower 5-20 parts, Chinese Incarvilla Herb 8-25 parts, Radix Glycyrrhizae (processed with honey) 8-20 parts.
2. the sick Chinese medicine composition for the treatment of Sarcocystis miescheriana according to claim 1, it is characterised in that by following weight portion Composition:8 parts of asafoetide, 6 parts of kuh-seng, 5 parts of common embelia fruit, 5 parts of Qinghai iris, 5 parts of bush, 8 parts of clearvers, 5 parts of radix semiaquilegiae, high mountain 9 parts of rough gentian, 8 parts of part, mao lotus dish of Tang Gute ultramarine 5, process 6 parts of radix bupleuri, 9 parts of root tuber of aromatic turmeric, 8 parts of Fructus Aurantii, 3 parts of fermented Chinese gall herb and tea leaves, Levant Cotton Root 5 Part, 5 parts of safflower, 8 parts of Chinese Incarvilla Herb, 8 parts of Radix Glycyrrhizae (processed with honey).
3. the sick Chinese medicine composition for the treatment of Sarcocystis miescheriana according to claim 1, it is characterised in that by following weight portion Composition:25 parts of asafoetide, 20 parts of kuh-seng, 20 parts of common embelia fruit, 20 parts of Qinghai iris, 25 parts of bush, 25 parts of clearvers, radix semiaquilegiae 20 Part, 25 parts of alpine gentian, 25 parts of part, mao lotus dish of Tang Gute ultramarine 20, process 20 parts of radix bupleuri, 25 parts of root tuber of aromatic turmeric, 20 parts of Fructus Aurantii, fermented Chinese gall herb and tea leaves 15 parts, 25 parts of Levant Cotton Root, 20 parts of safflower, 25 parts of Chinese Incarvilla Herb, 20 parts of Radix Glycyrrhizae (processed with honey).
4. the sick Chinese medicine composition for the treatment of Sarcocystis miescheriana according to claim 1, it is characterised in that by following weight portion Composition:9 parts of asafoetide, 7 parts of kuh-seng, 6 parts of common embelia fruit, 7 parts of Qinghai iris, 8 parts of bush, 10 parts of clearvers, 7 parts of radix semiaquilegiae, height 11 parts of mountain rough gentian, 9 parts of part, mao lotus dish of Tang Gute ultramarine 7, process 8 parts of radix bupleuri, 11 parts of root tuber of aromatic turmeric, 10 parts of Fructus Aurantii, 5 parts of fermented Chinese gall herb and tea leaves, cotton 7 parts of root, 6 parts of safflower, 10 parts of Chinese Incarvilla Herb, 10 parts of Radix Glycyrrhizae (processed with honey).
5. the sick Chinese medicine composition for the treatment of Sarcocystis miescheriana according to claim 1, it is characterised in that by following weight portion Composition:11 parts of asafoetide, 9 parts of kuh-seng, 8 parts of common embelia fruit, Qinghai iris 9 parts, 10 parts of bush, 12 parts of clearvers, 9 parts of radix semiaquilegiae, 13 parts of alpine gentian, 11 parts of part, mao lotus dish of Tang Gute ultramarine 9, process 10 parts of radix bupleuri, 13 parts of root tuber of aromatic turmeric, 12 parts of Fructus Aurantii, 7 parts of fermented Chinese gall herb and tea leaves, 9 parts of Levant Cotton Root, 8 parts of safflower, 12 parts of Chinese Incarvilla Herb, 12 parts of Radix Glycyrrhizae (processed with honey).
6. the sick Chinese medicine composition for the treatment of Sarcocystis miescheriana according to claim 1, it is characterised in that by following weight portion Composition:13 parts of asafoetide, 11 parts of kuh-seng, 10 parts of common embelia fruit, 12 parts of Qinghai iris, 12 parts of bush, 14 parts of clearvers, radix semiaquilegiae 11 Part, 15 parts of alpine gentian, 13 parts of part, mao lotus dish of Tang Gute ultramarine 14, process 12 parts of radix bupleuri, 15 parts of root tuber of aromatic turmeric, 14 parts of Fructus Aurantii, fermented Chinese gall herb and tea leaves 9 parts, 12 parts of Levant Cotton Root, 10 parts of safflower, 14 parts of Chinese Incarvilla Herb, 14 parts of Radix Glycyrrhizae (processed with honey).
7. the sick Chinese medicine composition for the treatment of Sarcocystis miescheriana according to claim 1, it is characterised in that by following weight portion Composition:16 parts of asafoetide, 13 parts of kuh-seng, 12 parts of common embelia fruit, 14 parts of Qinghai iris, 15 parts of bush, 16 parts of clearvers, radix semiaquilegiae 13 Part, 17 parts of alpine gentian, 15 parts of part, mao lotus dish of Tang Gute ultramarine 16, process 14 parts of radix bupleuri, 17 parts of root tuber of aromatic turmeric, 16 parts of Fructus Aurantii, fermented Chinese gall herb and tea leaves 12 parts, 15 parts of Levant Cotton Root, 12 parts of safflower, 16 parts of Chinese Incarvilla Herb, 16 parts of Radix Glycyrrhizae (processed with honey).
8. the sick Chinese medicine composition for the treatment of Sarcocystis miescheriana according to claim 1, it is characterised in that by following weight portion Composition:19 parts of asafoetide, 15 parts of kuh-seng, 14 parts of common embelia fruit, 14 parts of Qinghai iris, 18 parts of bush, 18 parts of clearvers, radix semiaquilegiae 16 Part, 20 parts of alpine gentian, 17 parts of part, mao lotus dish of Tang Gute ultramarine 18, process 16 parts of radix bupleuri, 19 parts of root tuber of aromatic turmeric, 18 parts of Fructus Aurantii, fermented Chinese gall herb and tea leaves 14 parts, 17 parts of Levant Cotton Root, 14 parts of safflower, 18 parts of Chinese Incarvilla Herb, 17 parts of Radix Glycyrrhizae (processed with honey).
9. the sick Chinese medicine composition for the treatment of Sarcocystis miescheriana according to claim 1, it is characterised in that by following weight portion Composition:22 parts of asafoetide, 17 parts of kuh-seng, 16 parts of common embelia fruit, 16 parts of Qinghai iris, 20 parts of bush, 20 parts of clearvers, radix semiaquilegiae 19 Part, 22 parts of alpine gentian, 20 parts of part, mao lotus dish of Tang Gute ultramarine 19, process 18 parts of radix bupleuri, 21 parts of root tuber of aromatic turmeric, 19 parts of Fructus Aurantii, fermented Chinese gall herb and tea leaves 11 parts, 20 parts of Levant Cotton Root, 16 parts of safflower, 20 parts of Chinese Incarvilla Herb, 18 parts of Radix Glycyrrhizae (processed with honey).
10. the sick Chinese medicine composition for the treatment of Sarcocystis miescheriana according to claim 1, it is characterised in that by following weight Part composition:24 parts of asafoetide, 19 parts of kuh-seng, 18 parts of common embelia fruit, 18 parts of Qinghai iris, 22 parts of bush, 23 parts of clearvers, radix semiaquilegiae 17 parts, 24 parts of alpine gentian, 23 parts of part, mao lotus dish of Tang Gute ultramarine 17, process 19 parts of radix bupleuri, 23 parts of root tuber of aromatic turmeric, 16 parts of Fructus Aurantii, hundred medicines Pan-fried 13 parts, 23 parts of Levant Cotton Root, 18 parts of safflower, 22 parts of Chinese Incarvilla Herb, 19 parts of Radix Glycyrrhizae (processed with honey).
CN201611100335.6A 2016-12-05 2016-12-05 Traditional Chinese medicine composition for treating pork sporozoosis Pending CN106620515A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102726625A (en) * 2012-06-03 2012-10-17 周剑峰 Traditional Chinese medicine feed additive for controlling pig sarcocystosis

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102726625A (en) * 2012-06-03 2012-10-17 周剑峰 Traditional Chinese medicine feed additive for controlling pig sarcocystosis

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