CN106551797A - Hand cleanser and preparation method thereof - Google Patents
Hand cleanser and preparation method thereof Download PDFInfo
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- CN106551797A CN106551797A CN201611001057.9A CN201611001057A CN106551797A CN 106551797 A CN106551797 A CN 106551797A CN 201611001057 A CN201611001057 A CN 201611001057A CN 106551797 A CN106551797 A CN 106551797A
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- ammonium chloride
- trimethyl ammonium
- hand cleanser
- quercetin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of hand cleanser and preparation method thereof, the hand cleanser is prepared from by following raw materials：13 parts of glycerine, 0.01 0.03 parts of vitamin A, 15 parts of sodium chloride, 0.1 0.5 parts of citric acid, 15 parts of α sodium olefin sulfonates, 5 15 parts of the clean skin factor, 0.02 0.2 parts of bacteriostatic agent, 75 95 parts of water.Hand cleanser of the present invention, rich in various natural components, can effectively kill germ, protection skin.
Description
Technical field
The present invention relates to daily-use chemical industry technical field, and in particular to a kind of hand cleanser and preparation method thereof.
Background technology
Hand cleanser is a kind of hand cleaning product for occurring in recent years.Which is compared with traditional perfumed soap, soap, it is to avoid perfume (or spice)
The solids such as soap, soap become easily infected by the defect of dirt on hand and bacterium, reduce the possibility of cross-infection, and, wash
Hand liquid can water-saving can save time again, foaming abundancy again can moistening hands while cleaning.However, the active component in hand cleanser
It is to use petroleum chemicals mostly, with the worsening shortages of oil, the production cost of hand cleanser certainly will be caused to rise.And, part
Hand cleanser is easily remained on skin as surfactant is using incorrect, it is difficult to rinse well, i.e., usage amount is little still
Feel not appearing to rinse well.Also there is the impact of the viscosity temperature of part hand cleanser very sensitive, the mobility in low temperature
Difference, in g., jelly-like, can not extruded at all.Also part hand cleanser carrys out regulation performance using lauric acid amide of ethanol, easily makes
It is exceeded into bacterium, or formaldehyde is used as preservative bacteria growing inhibiting.
At present as hand cleanser can be prevented effectively from the advantage of cross pollution in use, become public place washing and use
The first-selection of product.Existing hand cleanser generally existing cold washing detergency is not strong, and Disinfection Effect is not good, there is the stimulation to skin
The shortcomings of property.
The content of the invention
One kind is to provide for one of above-mentioned deficiency, the technical problem to be solved present in prior art to wash
Hand liquid.
The two of the technical problem of the solution of the present invention are to provide a kind of preparation method of hand cleanser.
The present invention seeks to be achieved through the following technical solutions：
A kind of hand cleanser, is prepared from by the raw material of following weight parts：Glycerine 1-3 parts, vitamin A 0.01-0.03 parts,
Sodium chloride 1-5 parts, citric acid 0.1-0.5 parts, α-sodium olefin sulfonate 1-5 parts, clean skin factor 5-15 part, bacteriostatic agent 0.02-0.2
Part, water 75-95 parts.
Preferably, the described clean skin factor is behenyl base trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, ten alkyl three
One or more of mixture in ammonio methacrylate.
It is highly preferred that the described clean skin factor is by behenyl base trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, ten alkyl
Trimethyl ammonium chloride is mixed, the behenyl base trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, ten alkyl trimethyl chlorine
The mass ratio for changing ammonium is (1-3)：(1-3)：(1-3).
Preferably, described bacteriostatic agent be Tea Saponin, glycyrrhizin, one or more of mixture in Quercetin.
It is highly preferred that described bacteriostatic agent is mixed by Tea Saponin, glycyrrhizin, Quercetin, the Tea Saponin, Radix Glycyrrhizae
Element, the mass ratio of Quercetin are (1-3)：(1-3)：(1-3).
Present invention also offers the preparation method of above-mentioned hand cleanser, comprises the following steps：
55-75 DEG C is heated water to, glycerine, the clean skin factor is sequentially added under stirring condition and is uniformly mixed, be cooled to
35-45 DEG C, sequentially add bacteriostatic agent, sodium chloride, citric acid, α-sodium olefin sulfonate, vitamin A and be uniformly mixed and obtain final product.
Specifically, in the present invention：
Vitamin A, No. CAS：11103-57-4.
Sodium chloride, No. CAS：7647-14-5.
Citric acid, No. CAS：77-92-9.
α-sodium olefin sulfonate, No. CAS：68439-57-6, the α-thiazolinyl sulphur provided using Sinolight Chemical Co., Ltd.
Sour sodium (powder).
Behenyl base trimethyl ammonium chloride, i.e. INCROQUAT TMC-80, No. CAS：17301-53-0.
Stearyl trimethyl ammonium chloride, No. CAS：112-03-8.
Decyl trimethyl ammonium chloride, No. CAS：10108-87-9.
Glycerine, No. CAS：56-81-5.
Tea Saponin, No. CAS：8047-15-2.
Glycyrrhizin, No. CAS：578-86-9.
Quercetin, No. CAS：117-39-5.
Hand cleanser of the present invention, rich in various natural components, can effectively kill germ, protection skin.
Specific embodiment
With reference to embodiment, the present invention is described further, described below, is only the preferable enforcement to the present invention
Example, not does the restriction of other forms to the present invention, and any those skilled in the art are possibly also with the disclosure above
Technology contents be changed to the Equivalent embodiments of equal change.It is every without departing from the present invention program content, according to the present invention
Technical spirit any simple modification that following examples are made or equivalent variations, all fall within protection scope of the present invention.
Embodiment 1
Hand cleanser raw material (weight portion)：2 parts of glycerine, 0.02 part of vitamin A, 3 parts of sodium chloride, 0.3 part of citric acid, α-alkene
3 parts of base sodium sulfonate, 12 parts of the clean skin factor, 0.03 part of bacteriostatic agent, 80 parts of water.
The described clean skin factor is by behenyl base trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, ten alkyl trimethyl chlorine
It is 1 in mass ratio to change ammonium：1：1 is uniformly mixed and obtains.
Described bacteriostatic agent is 1 by Tea Saponin, glycyrrhizin, Quercetin in mass ratio：1：1 is uniformly mixed and obtains.
The preparation method of above-mentioned hand cleanser, comprises the following steps：
65 DEG C are heated water to, glycerine, the clean skin factor is sequentially added under 500 revs/min of stirring conditions and is stirred mixing in 10 minutes
Uniformly, 40 DEG C are cooled to, bacteriostatic agent, sodium chloride, citric acid, α-sodium olefin sulfonate, vitamin A are sequentially added and is continued stirring 20
Minute is well mixed.Obtain the hand cleanser of embodiment 1.
Embodiment 2
It is substantially the same manner as Example 1, differ only in：Described bacteriostatic agent by glycyrrhizin, Quercetin is in mass ratio
1：1 is uniformly mixed and obtains.Obtain the hand cleanser of embodiment 2.
Embodiment 3
It is substantially the same manner as Example 1, differ only in：Described bacteriostatic agent by Tea Saponin, Quercetin is in mass ratio
1：1 is uniformly mixed and obtains.Obtain the hand cleanser of embodiment 3.
Embodiment 4
It is substantially the same manner as Example 1, differ only in：Described bacteriostatic agent by Tea Saponin, glycyrrhizin is in mass ratio
1：1 is uniformly mixed and obtains.Obtain the hand cleanser of embodiment 4.
Embodiment 5
It is substantially the same manner as Example 1, differ only in：The described clean skin factor by stearyl trimethyl ammonium chloride, ten
Alkyl trimethyl ammonium chloride is 1 in mass ratio：1 is uniformly mixed and obtains.Obtain the hand cleanser of embodiment 5.
Embodiment 6
It is substantially the same manner as Example 1, differ only in：The described clean skin factor by behenyl base trimethyl ammonium chloride, ten
Alkyl trimethyl ammonium chloride is 1 in mass ratio：1 is uniformly mixed and obtains.Obtain the hand cleanser of embodiment 6.
Embodiment 7
It is substantially the same manner as Example 1, differ only in：The described clean skin factor is by behenyl base trimethyl ammonium chloride, hard
Aliphatic radical trimethyl ammonium chloride is 1 in mass ratio：1 is uniformly mixed and obtains.Obtain the hand cleanser of embodiment 7.
Test case 1
According to professional standard QB/T 2850-2007 antibacterial bacteriostatic type detergent, fungistatic effect test, activity are carried out
1wt% is, action time is 20 minutes, and concrete detection data refers to table 1.
Table 1：Hand cleanser fungistatic effect tests table
Comparing embodiment 1 and embodiment 2-4, embodiment 1 (Tea Saponin, glycyrrhizin, Quercetin compounding) fungistatic effect are obvious
Better than embodiment 2-4 (arbitrarily the two compounding in Tea Saponin, glycyrrhizin, Quercetin)；Comparing embodiment 1 and embodiment 5-7, implement
Example 1 (behenyl base trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, decyl trimethyl ammonium chloride compounding) fungistatic effect is obvious
Better than embodiment 5-7 (in behenyl base trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, decyl trimethyl ammonium chloride arbitrarily
The two compounding).
Test case 2
Hand cleanser obtained in embodiment 1-7 gives the evaluation and test group of 45 people, and each embodiment dispenses 5 test specimens
Product, take the mode of random test that test sample is distributed to each member of this group, it is desirable to which group member is according to normal
Handwashing ways foam volume successively to test sample, dirt-removing power, mildness score, point system is made using 5 points, its
Middle evaluation grade takes its mean value calculation from 0～1 (extreme difference), 1～2 (poor), 2～3 (satisfactions), 3～4 (good), 4～5 (fine)
Restraining and sterilizing bacteria rate, gained assessment result see the table below 2.After relatively, each group carries out statistical analysis, as a result shows P ＜ 0.05, difference
With statistical significance.
Table 2：Detergency test result table
Comparing embodiment 1 and embodiment 2-4, embodiment 1 (Tea Saponin, glycyrrhizin, Quercetin compounding) sensory evaluation are obvious
Better than embodiment 2-4 (arbitrarily the two compounding in Tea Saponin, glycyrrhizin, Quercetin)；Comparing embodiment 1 and embodiment 5-7, implement
Example 1 (behenyl base trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, decyl trimethyl ammonium chloride compounding) sensory evaluation is obvious
Better than embodiment 5-7 (in behenyl base trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, decyl trimethyl ammonium chloride arbitrarily
The two compounding).
Claims (6)
1. a kind of hand cleanser, it is characterised in that be prepared from by the raw material of following weight parts：Glycerine 1-3 parts, vitamin A
It is 0.01-0.03 parts, sodium chloride 1-5 parts, citric acid 0.1-0.5 parts, α-sodium olefin sulfonate 1-5 parts, clean skin factor 5-15 part, antibacterial
Agent 0.02-0.2 parts, water 75-95 parts.
2. hand cleanser as claimed in claim 1, it is characterised in that：The described clean skin factor be behenyl base trimethyl ammonium chloride,
One or more of mixture in stearyl trimethyl ammonium chloride, decyl trimethyl ammonium chloride.
3. hand cleanser as claimed in claim 2, it is characterised in that：The described clean skin factor by behenyl base trimethyl ammonium chloride,
Stearyl trimethyl ammonium chloride, decyl trimethyl ammonium chloride are mixed, the behenyl base trimethyl ammonium chloride, stearyl three
Ammonio methacrylate, the mass ratio of decyl trimethyl ammonium chloride are (1-3)：(1-3)：(1-3).
4. the hand cleanser as any one of claim 1-3, it is characterised in that：Described bacteriostatic agent is Tea Saponin, Radix Glycyrrhizae
One or more of mixture in element, Quercetin.
5. hand cleanser as claimed in claim 4, it is characterised in that：Described bacteriostatic agent is mixed by Tea Saponin, glycyrrhizin, Quercetin
Conjunction is formed, and the Tea Saponin, glycyrrhizin, the mass ratio of Quercetin are (1-3)：(1-3)：(1-3).
6. the preparation method of the hand cleanser as any one of claim 1-5, it is characterised in that comprise the following steps：
55-75 DEG C is heated water to, glycerine, the clean skin factor is sequentially added under stirring condition and is uniformly mixed, be cooled to 35-45
DEG C, sequentially add bacteriostatic agent, sodium chloride, citric acid, α-sodium olefin sulfonate, vitamin A and be uniformly mixed and obtain final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611001057.9A CN106551797A (en) | 2016-11-14 | 2016-11-14 | Hand cleanser and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611001057.9A CN106551797A (en) | 2016-11-14 | 2016-11-14 | Hand cleanser and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106551797A true CN106551797A (en) | 2017-04-05 |
Family
ID=58444833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611001057.9A Withdrawn CN106551797A (en) | 2016-11-14 | 2016-11-14 | Hand cleanser and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106551797A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107320358A (en) * | 2017-08-25 | 2017-11-07 | 安庆徽云博冠化妆品科技有限公司 | A kind of Ai Xiang mildy wash and preparation method thereof |
| CN107616960A (en) * | 2017-09-30 | 2018-01-23 | 张建仁 | Biological antibiotic hand cleanser and its production technology |
-
2016
- 2016-11-14 CN CN201611001057.9A patent/CN106551797A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107320358A (en) * | 2017-08-25 | 2017-11-07 | 安庆徽云博冠化妆品科技有限公司 | A kind of Ai Xiang mildy wash and preparation method thereof |
| CN107616960A (en) * | 2017-09-30 | 2018-01-23 | 张建仁 | Biological antibiotic hand cleanser and its production technology |
| CN107616960B (en) * | 2017-09-30 | 2021-01-12 | 广州市雅创化妆品有限公司 | Biological sterilization hand sanitizer and production process thereof |
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| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170405 |