CN1064851C - 微粒，其制造方法以及在诊断中的应用 - Google Patents
微粒，其制造方法以及在诊断中的应用 Download PDFInfo
- Publication number
- CN1064851C CN1064851C CN931070155A CN93107015A CN1064851C CN 1064851 C CN1064851 C CN 1064851C CN 931070155 A CN931070155 A CN 931070155A CN 93107015 A CN93107015 A CN 93107015A CN 1064851 C CN1064851 C CN 1064851C
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- Prior art keywords
- microgranule
- necessity
- contrast agent
- acoustic contrast
- case
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acoustics & Sound (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4219723A DE4219723A1 (de) | 1992-06-13 | 1992-06-13 | Mikropartikel, Verfahren zu deren Herstellung, sowie die Verwendung dieser in der Diagnostik |
| DEP4219723.6 | 1992-06-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1082924A CN1082924A (zh) | 1994-03-02 |
| CN1064851C true CN1064851C (zh) | 2001-04-25 |
Family
ID=6461144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN931070155A Expired - Fee Related CN1064851C (zh) | 1992-06-13 | 1993-06-12 | 微粒，其制造方法以及在诊断中的应用 |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0644777B2 (ko) |
| JP (1) | JPH07507780A (ko) |
| KR (1) | KR100254746B1 (ko) |
| CN (1) | CN1064851C (ko) |
| AT (1) | ATE163134T1 (ko) |
| AU (1) | AU686103B2 (ko) |
| CA (1) | CA2138010A1 (ko) |
| DE (2) | DE4219723A1 (ko) |
| DK (1) | DK0644777T4 (ko) |
| ES (1) | ES2115060T5 (ko) |
| FI (1) | FI945837A0 (ko) |
| GR (1) | GR3026498T3 (ko) |
| HU (1) | HU217121B (ko) |
| IL (1) | IL105891A (ko) |
| NO (1) | NO307646B1 (ko) |
| NZ (1) | NZ253115A (ko) |
| TW (1) | TW239079B (ko) |
| WO (1) | WO1993025242A1 (ko) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5578292A (en) | 1991-11-20 | 1996-11-26 | Bracco International B.V. | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
| USRE39146E1 (en) | 1990-04-02 | 2006-06-27 | Bracco International B.V. | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
| US6989141B2 (en) | 1990-05-18 | 2006-01-24 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| US7083778B2 (en) | 1991-05-03 | 2006-08-01 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| US6613306B1 (en) | 1990-04-02 | 2003-09-02 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| NZ244147A (en) † | 1991-09-03 | 1994-09-27 | Hoechst Ag | Echogenic particles which comprise a gas and at least one shaping substance, and their use as diagnostic agents |
| IL104084A (en) | 1992-01-24 | 1996-09-12 | Bracco Int Bv | Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them |
| PT711179E (pt) * | 1993-07-30 | 2005-03-31 | Imcor Pharmaceutical Company | Composicoes de microbolhas estabilizadas para ultra-som |
| US5798091A (en) * | 1993-07-30 | 1998-08-25 | Alliance Pharmaceutical Corp. | Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement |
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| GB9800813D0 (en) | 1998-01-16 | 1998-03-11 | Andaris Ltd | Improved ultrasound contrast imaging method and apparatus |
| DE19925311B4 (de) | 1999-05-27 | 2004-06-09 | Schering Ag | Mehrstufen-Verfahren zur Herstellung von gasgefüllten Mikrokapseln |
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| CN1035437A (zh) * | 1988-02-05 | 1989-09-13 | 先灵公司 | 超声波造影剂及其制造方法和在诊断治疗中的应用 |
| CN1056634A (zh) * | 1990-05-18 | 1991-12-04 | 辛苔蒂加股份有限公司 | 超声回波记录仪用液载悬浮体之充气聚合物微气球 |
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| US4265251A (en) * | 1979-06-28 | 1981-05-05 | Rasor Associates, Inc. | Method of determining pressure within liquid containing vessel |
| NZ244147A (en) * | 1991-09-03 | 1994-09-27 | Hoechst Ag | Echogenic particles which comprise a gas and at least one shaping substance, and their use as diagnostic agents |
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1992
- 1992-06-13 DE DE4219723A patent/DE4219723A1/de not_active Withdrawn
-
1993
- 1993-06-02 IL IL10589193A patent/IL105891A/en not_active IP Right Cessation
- 1993-06-05 DE DE59308146T patent/DE59308146D1/de not_active Expired - Fee Related
- 1993-06-05 EP EP93912897A patent/EP0644777B2/de not_active Expired - Lifetime
- 1993-06-05 CA CA002138010A patent/CA2138010A1/en not_active Abandoned
- 1993-06-05 NZ NZ253115A patent/NZ253115A/en unknown
- 1993-06-05 KR KR1019940704526A patent/KR100254746B1/ko not_active IP Right Cessation
- 1993-06-05 AT AT93912897T patent/ATE163134T1/de not_active IP Right Cessation
- 1993-06-05 AU AU43232/93A patent/AU686103B2/en not_active Ceased
- 1993-06-05 WO PCT/EP1993/001425 patent/WO1993025242A1/de active IP Right Grant
- 1993-06-05 HU HU9403566A patent/HU217121B/hu not_active IP Right Cessation
- 1993-06-05 DK DK93912897T patent/DK0644777T4/da active
- 1993-06-05 JP JP6501098A patent/JPH07507780A/ja not_active Ceased
- 1993-06-05 ES ES93912897T patent/ES2115060T5/es not_active Expired - Lifetime
- 1993-06-12 CN CN931070155A patent/CN1064851C/zh not_active Expired - Fee Related
- 1993-06-15 TW TW082104757A patent/TW239079B/zh active
-
1994
- 1994-12-12 FI FI945837A patent/FI945837A0/fi not_active Application Discontinuation
- 1994-12-12 NO NO944805A patent/NO307646B1/no unknown
-
1998
- 1998-04-03 GR GR980400681T patent/GR3026498T3/el unknown
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1035437A (zh) * | 1988-02-05 | 1989-09-13 | 先灵公司 | 超声波造影剂及其制造方法和在诊断治疗中的应用 |
| CN1056634A (zh) * | 1990-05-18 | 1991-12-04 | 辛苔蒂加股份有限公司 | 超声回波记录仪用液载悬浮体之充气聚合物微气球 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR100254746B1 (ko) | 2000-08-01 |
| ES2115060T3 (es) | 1998-06-16 |
| WO1993025242A1 (de) | 1993-12-23 |
| FI945837A (fi) | 1994-12-12 |
| HUT69380A (en) | 1995-09-28 |
| DK0644777T4 (da) | 2004-02-23 |
| NO307646B1 (no) | 2000-05-08 |
| DE59308146D1 (de) | 1998-03-19 |
| EP0644777A1 (de) | 1995-03-29 |
| EP0644777B2 (de) | 2003-10-15 |
| EP0644777B1 (de) | 1998-02-11 |
| AU686103B2 (en) | 1998-02-05 |
| HU9403566D0 (en) | 1995-02-28 |
| NO944805D0 (no) | 1994-12-12 |
| ES2115060T5 (es) | 2004-06-16 |
| DK0644777T3 (da) | 1998-09-23 |
| HU217121B (hu) | 1999-11-29 |
| NO944805L (no) | 1994-12-12 |
| CN1082924A (zh) | 1994-03-02 |
| GR3026498T3 (en) | 1998-07-31 |
| TW239079B (ko) | 1995-01-21 |
| JPH07507780A (ja) | 1995-08-31 |
| ATE163134T1 (de) | 1998-02-15 |
| CA2138010A1 (en) | 1993-12-23 |
| FI945837A0 (fi) | 1994-12-12 |
| IL105891A0 (en) | 1993-10-20 |
| NZ253115A (en) | 1996-01-26 |
| IL105891A (en) | 1998-10-30 |
| KR950701823A (ko) | 1995-05-17 |
| AU4323293A (en) | 1994-01-04 |
| DE4219723A1 (de) | 1993-12-16 |
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