CN106472503B - A kind of composite bactericide and preparation method - Google Patents
A kind of composite bactericide and preparation method Download PDFInfo
- Publication number
- CN106472503B CN106472503B CN201610807377.7A CN201610807377A CN106472503B CN 106472503 B CN106472503 B CN 106472503B CN 201610807377 A CN201610807377 A CN 201610807377A CN 106472503 B CN106472503 B CN 106472503B
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- Prior art keywords
- dimethachlon
- composite bactericide
- hydroximic acid
- dosage
- mixed
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
- A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
- A01N37/32—Cyclic imides of polybasic carboxylic acids or thio analogues thereof
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of composite bactericide and preparation method, a kind of composite bactericide is made of a certain proportion of dimethachlon raw medicine, Salicyl Hydroximic Acid, neopelex, sodium lignin sulfonate, diatomite or bentonite, step:1）By prepared dosage form demand, dosage is calculated, weighs raw medicine, Salicyl Hydroximic Acid, neopelex, water quality element sodium sulfonate and diatomite in container, mixed, crushed in pulverizer；2）The sample of crushing is mixed, is crushed to certain fineness through air-flow powder machine（95% passes through 320 meshes）, it is uniformly mixed so as to obtain dimethachlon wettable powder.Formula is rationally, easy to use, has apparent synergistic effect to dimethachlon on prevention and treatment sclerotinia sclerotiorum, it is remarkably improved the control efficiency of dimethachlon, to crop safety, without phytotoxicity, the dosage of dimethachlon can be reduced, control cost is reduced, and is expected to delay the generation to dimethachlon drug resistance.
Description
Technical field
The invention belongs to disinfectant use in agriculture, are more particularly to a kind of composite bactericide, also relate to a kind of compound sterilizing
The preparation method of agent, it is suitable for the prevention and treatment of sclerotinia sclerotiorum.
Background technique
Sclerotinia sclerotiorum (oilseed rape Sclerotinia stem rot) is by sclerotinite [Sclerotinia
Sclerotiorum (Lib.) de Bary] caused by a kind of worldwide fungal disease, the pathogen main harm rape leaf,
Stalk and pod have generation in Winter-Spring rape cultivation area of China, wherein it is the most serious with the Yangtze river basin and southwestern coastal area,
General time disease incidence is 10%-30%, and popular time serious field disease incidence can be more than 80%, leads to the direct underproduction 73%,
The yield and quality of rape is seriously affected.
Dimethachlon (Dimethachlone) is dicarboximide fungicide.Dimethachlon is protective fungicide, is had certain
Interior suction therapeutic effect.It is mainly used for preventing and treating rice sheath blight disease and sclerotinia sclerotiorum, Alternaria alternate.
Salicyl Hydroximic Acid (Salicylhydroxami acid) is a kind of medicine intermediate, as chemical analysis precipitating reagent,
Analyze the reagent of bismuth, copper, nickel and copper.Salicyl Hydroximic Acid can form stable chelate with metals such as tin, tungsten, rare earth, copper, iron,
And unstable chelate is formed with alkaline-earth metal and alkali metal, so, Salicyl Hydroximic Acid has preferable selectivity.Bigcatkin willow hydroxyl
Oxime acid, which can inhibit, bypasses oxidizing ferment in plant pathogenic fungi body, be used for indoor measurement methoxy acrylic
(Strobilurin) virulence of the fungicide to pathogen.Salicyl Hydroximic Acid toxicity is low, safer to environment.
Summary of the invention
The purpose of the invention is to provide a kind of composite bactericides, and formula is rationally, easy to use, in prevention and treatment Sclerotina Sclerotiorum in Winter Rape
There is apparent synergistic effect to dimethachlon in core disease, be remarkably improved the control efficiency of dimethachlon, the use of dimethachlon can be reduced
Amount, reduces control cost, and be expected to delay the generation to dimethachlon drug resistance.
In order to achieve the above purpose, the present invention uses following technical measures：
A kind of composite bactericide, it is made of the mass fraction of following raw material：
In above-mentioned composite bactericide, the weight ratio of dimethachlon and Salicyl Hydroximic Acid is 15:1-1:4.
A kind of composite bactericide, (preferred scope) is made by the mass fraction of following raw material in it：
A kind of composite bactericide, (preferable range) is made by the mass fraction of following raw material in it：
A kind of composite bactericide, (best range) is made by the mass fraction of following raw material in it：
A kind of composite bactericide, (optimum value) is made by the mass fraction of following raw material in it：
A kind of preparation method of composite bactericide, reference《Pesticide formulation experiment》(Wu Xuemin Xu Yan chief editor, chemical work
Industry publishing house, 2009), step is:
1) prepared dosage form demand is pressed, dosage is calculated, weighs raw medicine, Salicyl Hydroximic Acid, neopelex, water
Quality sodium sulfonate and diatomite are mixed, are tentatively crushed in pulverizer in container；
2) sample tentatively crushed is mixed, is crushed to certain fineness (95% passes through 320 meshes) through air-flow powder machine, mixes
Obtain dimethachlon wettable powder.
Compared with prior art, the present invention having the following advantages that and effect：
With synergistic effect, to crop safety, without phytotoxicity, low toxicity.It can be used for preventing and treating sclerotinia sclerotiorum, be to kill with dimethachlon
Bacterium active ingredient, with Salicyl Hydroximic Acid for main auxiliary agent；Two kinds of ingredient compoundings, have significant synergies, the two is 15：1
To 1：In 4 ratio ranges, the poison factor be 26-53 (altogether poison because of Zi≤20 be synergistic effect) altogether.It is wettable with the dimethachlon in current city
Property pulvis is compared, and is remarkably improved dimethachlon to the control efficiency of sclerotinia sclerotiorum, and reduce the dosage of dimethachlon.With not
Add the dimethachlon single dose of Salicyl Hydroximic Acid to compare, in dimethachlon same concentrations, the preventive effect of sclerotinia sclerotiorum can be improved
34%.Processed compound preparation is in the undiminished situation of control efficiency, it is possible to reduce the dosage of dimethachlon 50%.
Specific embodiment
Embodiment 1：
A kind of composite bactericide (40% dimethachlon (15：1) wettable powder), it by following raw material mass fraction system
At：
A kind of preparation method of composite bactericide, step are:
1) prepared dosage form demand is pressed, dosage is calculated, weighs raw medicine, Salicyl Hydroximic Acid, neopelex, water
Quality sodium sulfonate and diatomite are mixed, are tentatively crushed in pulverizer in container；
2) sample tentatively crushed is mixed, is crushed to certain fineness (95% passes through 320 meshes) through air-flow powder machine, mixes
Obtain 40% dimethachlon wettable powder.
Above-mentioned preparation method reference《Pesticide formulation experiment》(Wu Xuemin Xu Yan chief editor, Chemical Industry Press,
2009)
Embodiment 2：
40% dimethachlon (4：1) wettable powder, it is made of the mass fraction of following raw material：
Its preparation step is same as Example 1.
Embodiment 3：
20% dimethachlon (1：1) wettable powder, it is made of the mass fraction of following raw material：
Its preparation step is same as Example 1.
Embodiment 4：
10% dimethachlon (1：4) wettable powder, it is made of the mass fraction of following raw material：
Its preparation step is same as Example 1.
A kind of composite bactericide, it is made of the mass fraction of following raw material
Its preparation step is same as Example 1.
The wettable powder of above example 1-4 processing carries out the experiment of potting rape control efficiency, chooses the consistent oil of growing way
Dish plant, the wettable powder processed is spraying after diluting 2000 times with tap water, with commercially available 40% dimethachlon wettable powder
For comparison medicament.Clear water is sprayed as blank control.It is inoculated with PDA fungus block (diameter 5mm) after spraying airing, every leaf connects 1 PDA bacterium
Block, 2 fungus blocks of every plant of inoculation.In cultivating in greenhouse after inoculation, temperature is controlled at 23 DEG C or so.Inspection result after 72 hours is surveyed
Lesion size is measured, the lesion diameter that do not fall ill is calculated as 0, calculates control efficiency as follows according to Lesion size.
Control efficiency (%)=(control group lesion diameter-processing group lesion diameter)/control group lesion diameter × 100 are every
Chemicals treatment sets 5 repetitions (rapeseed plants), this test is repeated 2 times.
Control efficiency shows that the control efficiency of comparison medicament is 61%, processed dimethachlon wettable powder (example 1-4)
Control efficiency be respectively 74%, 82%, 78% and 68%, therefore, Salicyl Hydroximic Acid is remarkably improved dimethachlon to Sclerotina Sclerotiorum in Winter Rape
The preventive effect of core disease, and the dosage of dimethachlon can be reduced.
In experiments it is found that individual Salicyl Hydroximic Acid also has certain preventive and therapeutic effect to the sclerotiniose on rape, therefore,
Using Salicyl Hydroximic Acid as a kind of bacteriostatic active ingredients, using total poison therefore method determines Salicyl Hydroximic Acid and dimethachlon difference and matches
The synergistic effect of ratio, calculation formula are as follows：
The total malicious factor (CTF)=(the theoretical control efficiency of practical control efficiency-mixture of mixture)/mixture of mixture
Theoretical control efficiency × 100.
Wherein：The theoretical control efficiency of mixture=(dimethachlon control efficiency+Salicyl Hydroximic Acid control efficiency)-(dimethachlon
Control efficiency × Salicyl Hydroximic Acid control efficiency)
CTF>20 be synergistic effect, CTF<- 20 be antagonism, -20<CTF<20 be summation action.
The total malicious factor of 1 dimethachlon of table and Salicyl Hydroximic Acid different ratio to sclerotinia sclerotiorum
From the above results, it can be seen that dimethachlon and Salicyl Hydroximic Acid are 15：1 to 1：Synergistic effect is shown in the range of 4.
With 4：Synergistic effect is the most significant when 1.
Experiment show dimethachlon and Salicyl Hydroximic Acid compounding have good synergistic effect, above by specific example to
Present invention be described in more detail, but the present invention is only limited to absolutely not the above embodiment.Percentage is weight in formula
Percentage, used raw medicine and auxiliary agent are existing product (purchase of other producers).
Claims (7)
1. a kind of composite bactericide, it is made of the mass fraction of following raw material：
2. a kind of composite bactericide according to claim 1, it is characterised in that：
3. a kind of composite bactericide according to claim 1, it is characterised in that：
4. a kind of composite bactericide according to claim 1, it is characterised in that：
5. a kind of composite bactericide according to claim 1, it is characterised in that：
6. a kind of composite bactericide according to claim 1, it is characterised in that：
7. a kind of composite bactericide according to claim 1, it is characterised in that：
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610807377.7A CN106472503B (en) | 2016-09-07 | 2016-09-07 | A kind of composite bactericide and preparation method |
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| CN201610807377.7A CN106472503B (en) | 2016-09-07 | 2016-09-07 | A kind of composite bactericide and preparation method |
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| Publication Number | Publication Date |
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| CN106472503A CN106472503A (en) | 2017-03-08 |
| CN106472503B true CN106472503B (en) | 2018-11-20 |
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| Application Number | Title | Priority Date | Filing Date |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102197818A (en) * | 2010-03-22 | 2011-09-28 | 中国中化股份有限公司 | Bactericidal composition |
| CN103329915A (en) * | 2013-05-09 | 2013-10-02 | 华中农业大学 | Sterilization composition containing thiram and dimethachlon, and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2656311B2 (en) * | 1988-08-22 | 1997-09-24 | 株式会社渡辺採種場 | Male sterility-inducing agent, method for inducing male sterility using the same, and F method |
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2016
- 2016-09-07 CN CN201610807377.7A patent/CN106472503B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102197818A (en) * | 2010-03-22 | 2011-09-28 | 中国中化股份有限公司 | Bactericidal composition |
| CN103329915A (en) * | 2013-05-09 | 2013-10-02 | 华中农业大学 | Sterilization composition containing thiram and dimethachlon, and preparation method thereof |
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| Publication number | Publication date |
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| CN106472503A (en) | 2017-03-08 |
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