CN106459906B - 皮肤源性前体细胞的制造方法 - Google Patents

皮肤源性前体细胞的制造方法 Download PDF

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CN106459906B
CN106459906B CN201580025674.XA CN201580025674A CN106459906B CN 106459906 B CN106459906 B CN 106459906B CN 201580025674 A CN201580025674 A CN 201580025674A CN 106459906 B CN106459906 B CN 106459906B
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cells
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skps
differentiation
derived
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CN106459906A (zh
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中桐赖子
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Kao Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/415—Wnt; Frizzeled
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201580025674.XA 2014-04-21 2015-04-20 皮肤源性前体细胞的制造方法 Expired - Fee Related CN106459906B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2014087247 2014-04-21
JP2014-087247 2014-04-21
JP2014-260434 2014-12-24
JP2014260434A JP6304818B2 (ja) 2014-04-21 2014-12-24 皮膚由来多能性前駆細胞の作製方法
PCT/JP2015/002156 WO2015162908A1 (en) 2014-04-21 2015-04-20 Method of producing skin-derived precursor cells

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CN106459906A CN106459906A (zh) 2017-02-22
CN106459906B true CN106459906B (zh) 2021-10-29

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US (2) US20170044495A1 (enExample)
EP (1) EP3134513B1 (enExample)
JP (1) JP6304818B2 (enExample)
KR (1) KR102316007B1 (enExample)
CN (1) CN106459906B (enExample)
WO (1) WO2015162908A1 (enExample)

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
SG11201700095SA (en) 2014-07-09 2017-02-27 Sanford Burnham Med Res Inst Methods and compositions to modulate hair growth
WO2017136834A1 (en) 2016-02-05 2017-08-10 Memorial Sloan-Ketering Cancer Center Methods of differentiating stem cell-derived ectodermal lineage precursors
WO2019017691A2 (ko) * 2017-07-19 2019-01-24 서울대학교 산학협력단 인간 유래 만능줄기세포에서 모유두전구세포로의 분화방법 및 이의 용도
US11629331B2 (en) 2017-07-19 2023-04-18 Seoul National University R & Db Foundation Method of differentiation of human induced pluripotent stem cell to dermal papilla precursor cell and use thereof
WO2019051248A1 (en) * 2017-09-07 2019-03-14 Memorial Sloan-Kettering Cancer Center METHODS FOR DIFFERENTIATING PRECURSORS OF ECTODERMIC LINES DERIVED FROM STEM CELLS
BR112020010539A2 (pt) 2017-11-30 2020-11-17 Kyoto University métodos para produção e para proliferação de células da crista neural, para produção de células nervosas, células da glia, células estromais mesenquimais, células ósseas, condrócitos, células da córnea ou células pigmentares e para cultivar células da crista neural, meio, estoque congelado, e, uso de um meio
JP7702229B2 (ja) * 2018-11-19 2025-07-03 株式会社 資生堂 毛包を有するヒト皮膚組織を再構成するための組成物、ヒト皮膚組織モデル動物およびその製造方法
CN114207111B (zh) * 2019-08-06 2025-05-30 花王株式会社 皮肤源性多能性前体细胞的制作方法
CN114591894B (zh) * 2022-02-28 2024-01-09 中国人民解放军总医院 一种皮肤多能前体干细胞的制备方法及其应用

Citations (2)

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WO2010011352A2 (en) * 2008-07-25 2010-01-28 The University Of Georgia Research Foundation, Inc. Compositions for mesoderm derived isl1+ multipotent cells (imps), epicardial progenitor cells (epcs) and multipotent cxcr4+cd56+ cells (c56cs) and methods of use
CN103230623A (zh) * 2013-05-10 2013-08-07 南通大学 一种体外构建组织工程化神经的方法

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EP1772514A3 (en) 1999-07-12 2007-06-20 Walter Gehring Manipulation of tissue or organ type using the notch pathway
EP2453010A1 (en) * 2000-03-14 2012-05-16 ES Cell International Pte Ltd. Neural progenitor cells derived from embryonic stem cells
CA2554732C (en) * 2004-01-27 2014-07-15 The Hospital For Sick Children Methods of making and using skin-derived stem cells
WO2007016485A2 (en) * 2005-07-29 2007-02-08 Athersys, Inc. Use of a gsk-3 inhibitor to maintain potency of cultured cells
EP1996013A4 (en) 2005-09-21 2010-03-10 Dask Technologies Llc METHODS AND COMPOSITIONS FOR FUNCTIONALITY OF ORGANS AND TISSUES
US20080213892A1 (en) * 2007-03-02 2008-09-04 The Board Of Trustees Of The Leland Stanford Junior University Self-renewal of neural stem cells is promoted by wnt proteins
EP2042592A1 (en) 2007-09-28 2009-04-01 IMBA-Institut für Molekulare Biotechnologie GmbH Methods for modulating the proliferation and differentiation potential of stem cells and progenitor cells
EP2658966B1 (en) * 2010-12-31 2017-04-05 University of Georgia Research Foundation, Inc. Differentiation of human pluripotent stem cells to multipotent neural crest cells
US9347042B2 (en) * 2011-10-06 2016-05-24 Keio University Method for producing corneal endothelial cell

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2010011352A2 (en) * 2008-07-25 2010-01-28 The University Of Georgia Research Foundation, Inc. Compositions for mesoderm derived isl1+ multipotent cells (imps), epicardial progenitor cells (epcs) and multipotent cxcr4+cd56+ cells (c56cs) and methods of use
CN103230623A (zh) * 2013-05-10 2013-08-07 南通大学 一种体外构建组织工程化神经的方法

Non-Patent Citations (2)

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皮肤源性前体细胞的生物学特性与临床应用;Li Zong-zhe et al.;《中国组织工程研究与临床康复》;20110806;第15卷(第32期);第6056-6059页 *

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Publication number Publication date
CN106459906A (zh) 2017-02-22
EP3134513B1 (en) 2019-03-06
WO2015162908A1 (en) 2015-10-29
US20170044495A1 (en) 2017-02-16
JP6304818B2 (ja) 2018-04-04
KR102316007B1 (ko) 2021-10-21
EP3134513A1 (en) 2017-03-01
JP2015213495A (ja) 2015-12-03
KR20160145170A (ko) 2016-12-19
US20220348868A1 (en) 2022-11-03

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