CN106456951B - 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法 - Google Patents

包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法 Download PDF

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CN106456951B
CN106456951B CN201580033832.6A CN201580033832A CN106456951B CN 106456951 B CN106456951 B CN 106456951B CN 201580033832 A CN201580033832 A CN 201580033832A CN 106456951 B CN106456951 B CN 106456951B
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drug
matrix system
silicone
lumen
bladder
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CN106456951A (zh
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李喜真
卡伦·丹尼尔
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Liris Biomedical Inc
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Taris Biomedical Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0009—Making of catheters or other medical or surgical tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216—Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1078—Urinary tract
    • A61M2210/1085—Bladder

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
CN201580033832.6A 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法 Active CN106456951B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202111310044.0A CN114306899A (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462017775P 2014-06-26 2014-06-26
US62/017,775 2014-06-26
PCT/US2015/037887 WO2015200752A1 (en) 2014-06-26 2015-06-26 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems

Related Child Applications (1)

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CN202111310044.0A Division CN114306899A (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法

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CN106456951A CN106456951A (zh) 2017-02-22
CN106456951B true CN106456951B (zh) 2021-11-05

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CN201580033832.6A Active CN106456951B (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法
CN202111310044.0A Pending CN114306899A (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法

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US (3) US10737078B2 (enExample)
EP (3) EP3160442B1 (enExample)
JP (3) JP6856380B2 (enExample)
KR (4) KR102391761B1 (enExample)
CN (2) CN106456951B (enExample)
AU (4) AU2015279674B2 (enExample)
DK (1) DK3160442T3 (enExample)
ES (2) ES2940478T3 (enExample)
WO (1) WO2015200752A1 (enExample)

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US20180117219A1 (en) * 2015-04-29 2018-05-03 Northwestern University 3d printing of biomedical implants
WO2017132372A1 (en) 2016-01-26 2017-08-03 Taris Biomedical Llc Multi-lumen drug delivery devices
ES2940227T3 (es) 2016-05-06 2023-05-04 Taris Biomedical Llc Método de tratamiento del cáncer urotelial del tracto inferior
WO2019023388A1 (en) 2017-07-25 2019-01-31 Taris Biomedical Llc METHODS OF TREATING TUMOR METASTASIS
PE20210041A1 (es) 2017-11-08 2021-01-08 Taris Biomedical Llc Metodos de tratamiento y terapia de mantenimiento para el cancer de vejiga con gemcitabina
US20190365645A1 (en) 2018-05-31 2019-12-05 Massachusetts Institute Of Technology Drug delivery articles for gram-level dosing
CA3107461A1 (en) 2018-08-01 2020-02-06 Taris Biomedical Llc Methods of treating overactive bladder using trospium
CN117982783A (zh) * 2018-11-09 2024-05-07 塔里斯生物医药公司 用于将药物局部递送到上尿道的药物递送装置和系统
US20240016731A1 (en) * 2020-09-28 2024-01-18 The Regents Of The University Of California Drug Implants Containing Apalutamide and Methods of Use Thereof
MX2024007818A (es) 2021-12-21 2024-09-06 Taris Biomedical Llc Catéter de colocación urinario para dispositivos intravesicales.
CN115120854B (zh) * 2022-07-04 2023-10-13 奥格生物技术（六安）有限公司 前列腺自然直接给药装置
WO2024092159A1 (en) 2022-10-28 2024-05-02 Taris Biomedical Llc Methods of treating bladder cancer with gemcitabine
WO2024215682A1 (en) 2023-04-10 2024-10-17 Taris Biomedical Llc Gemcitabine for use in methods of treating high-risk non-muscle invasive bladder cancer unresponsive to bacillus calmette-guerin therapy
WO2025076007A1 (en) 2023-10-02 2025-04-10 Taris Biomedical Llc Methods of treating high-risk non-muscle invasive bladder cancer unresponsive to bacillus calmette-guérin therapy

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CN102596174A (zh) * 2009-09-10 2012-07-18 塔里斯生物医药公司 用于受控的药物递送的可植入装置
US8679094B2 (en) * 2009-12-17 2014-03-25 Taris Biomedical, Inc. Implantable device with intravesical tolerability and methods of treatment

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CN102470237A (zh) * 2009-06-26 2012-05-23 塔里斯生物医药公司 用于可植入药物递送装置的固体药物片剂
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US8679094B2 (en) * 2009-12-17 2014-03-25 Taris Biomedical, Inc. Implantable device with intravesical tolerability and methods of treatment

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EP4173615A2 (en) 2023-05-03
JP6856380B2 (ja) 2021-04-07
JP7005668B2 (ja) 2022-01-21
US11904123B2 (en) 2024-02-20
US20200368508A1 (en) 2020-11-26
AU2020250209A1 (en) 2020-11-05
WO2015200752A8 (en) 2016-08-11
EP4173615A3 (en) 2023-07-19
CN106456951A (zh) 2017-02-22
AU2015279674A1 (en) 2017-01-12
AU2015279674B2 (en) 2020-07-23
AU2022204523B2 (en) 2024-05-16
US12239807B2 (en) 2025-03-04
EP3517099B1 (en) 2022-12-28
EP3517099A1 (en) 2019-07-31
WO2015200752A1 (en) 2015-12-30
EP3160442A1 (en) 2017-05-03
US10737078B2 (en) 2020-08-11
AU2020250209B2 (en) 2022-07-14
US20200368509A1 (en) 2020-11-26
JP2020110615A (ja) 2020-07-27
KR102391761B1 (ko) 2022-04-27
EP3160442B1 (en) 2019-03-06
AU2022204523A1 (en) 2022-07-21
JP2017524421A (ja) 2017-08-31
ES2940478T3 (es) 2023-05-08
JP2022022292A (ja) 2022-02-03
KR20170026465A (ko) 2017-03-08
KR20220061253A (ko) 2022-05-12
AU2024204468A1 (en) 2024-07-18
KR20220061254A (ko) 2022-05-12
US20170165460A1 (en) 2017-06-15
CN114306899A (zh) 2022-04-12
KR20230142816A (ko) 2023-10-11
DK3160442T3 (da) 2019-06-11
ES2728504T3 (es) 2019-10-25
KR102486216B1 (ko) 2023-01-09

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