AU2015279674B2 - Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems - Google Patents

Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems Download PDF

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Publication number
AU2015279674B2
AU2015279674B2 AU2015279674A AU2015279674A AU2015279674B2 AU 2015279674 B2 AU2015279674 B2 AU 2015279674B2 AU 2015279674 A AU2015279674 A AU 2015279674A AU 2015279674 A AU2015279674 A AU 2015279674A AU 2015279674 B2 AU2015279674 B2 AU 2015279674B2
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AU
Australia
Prior art keywords
drug
silicone
matrix system
lumen
elastic
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AU2015279674A
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English (en)
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AU2015279674A1 (en
Inventor
Karen Daniel
Heejin Lee
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Taris Biomedical LLC
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Taris Biomedical LLC
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Publication of AU2015279674A1 publication Critical patent/AU2015279674A1/en
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Publication of AU2015279674B2 publication Critical patent/AU2015279674B2/en
Priority to AU2020250209A priority Critical patent/AU2020250209B2/en
Priority to AU2022204523A priority patent/AU2022204523B2/en
Priority to AU2024204468A priority patent/AU2024204468A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0009—Making of catheters or other medical or surgical tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216—Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1078—Urinary tract
    • A61M2210/1085—Bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
AU2015279674A 2014-06-26 2015-06-26 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems Active AU2015279674B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2020250209A AU2020250209B2 (en) 2014-06-26 2020-10-07 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems
AU2022204523A AU2022204523B2 (en) 2014-06-26 2022-06-27 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems
AU2024204468A AU2024204468A1 (en) 2014-06-26 2024-06-28 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462017775P 2014-06-26 2014-06-26
US62/017,775 2014-06-26
PCT/US2015/037887 WO2015200752A1 (en) 2014-06-26 2015-06-26 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2020250209A Division AU2020250209B2 (en) 2014-06-26 2020-10-07 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems

Publications (2)

Publication Number Publication Date
AU2015279674A1 AU2015279674A1 (en) 2017-01-12
AU2015279674B2 true AU2015279674B2 (en) 2020-07-23

Family

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Family Applications (4)

Application Number Title Priority Date Filing Date
AU2015279674A Active AU2015279674B2 (en) 2014-06-26 2015-06-26 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems
AU2020250209A Active AU2020250209B2 (en) 2014-06-26 2020-10-07 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems
AU2022204523A Active AU2022204523B2 (en) 2014-06-26 2022-06-27 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems
AU2024204468A Pending AU2024204468A1 (en) 2014-06-26 2024-06-28 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU2020250209A Active AU2020250209B2 (en) 2014-06-26 2020-10-07 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems
AU2022204523A Active AU2022204523B2 (en) 2014-06-26 2022-06-27 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems
AU2024204468A Pending AU2024204468A1 (en) 2014-06-26 2024-06-28 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems

Country Status (9)

Country Link
US (3) US10737078B2 (enExample)
EP (3) EP3160442B1 (enExample)
JP (3) JP6856380B2 (enExample)
KR (4) KR102391761B1 (enExample)
CN (2) CN106456951B (enExample)
AU (4) AU2015279674B2 (enExample)
DK (1) DK3160442T3 (enExample)
ES (2) ES2940478T3 (enExample)
WO (1) WO2015200752A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180117219A1 (en) * 2015-04-29 2018-05-03 Northwestern University 3d printing of biomedical implants
WO2017132372A1 (en) 2016-01-26 2017-08-03 Taris Biomedical Llc Multi-lumen drug delivery devices
ES2940227T3 (es) 2016-05-06 2023-05-04 Taris Biomedical Llc Método de tratamiento del cáncer urotelial del tracto inferior
WO2019023388A1 (en) 2017-07-25 2019-01-31 Taris Biomedical Llc METHODS OF TREATING TUMOR METASTASIS
PE20210041A1 (es) 2017-11-08 2021-01-08 Taris Biomedical Llc Metodos de tratamiento y terapia de mantenimiento para el cancer de vejiga con gemcitabina
US20190365645A1 (en) 2018-05-31 2019-12-05 Massachusetts Institute Of Technology Drug delivery articles for gram-level dosing
CA3107461A1 (en) 2018-08-01 2020-02-06 Taris Biomedical Llc Methods of treating overactive bladder using trospium
CN117982783A (zh) * 2018-11-09 2024-05-07 塔里斯生物医药公司 用于将药物局部递送到上尿道的药物递送装置和系统
US20240016731A1 (en) * 2020-09-28 2024-01-18 The Regents Of The University Of California Drug Implants Containing Apalutamide and Methods of Use Thereof
MX2024007818A (es) 2021-12-21 2024-09-06 Taris Biomedical Llc Catéter de colocación urinario para dispositivos intravesicales.
CN115120854B (zh) * 2022-07-04 2023-10-13 奥格生物技术（六安）有限公司 前列腺自然直接给药装置
WO2024092159A1 (en) 2022-10-28 2024-05-02 Taris Biomedical Llc Methods of treating bladder cancer with gemcitabine
WO2024215682A1 (en) 2023-04-10 2024-10-17 Taris Biomedical Llc Gemcitabine for use in methods of treating high-risk non-muscle invasive bladder cancer unresponsive to bacillus calmette-guerin therapy
WO2025076007A1 (en) 2023-10-02 2025-04-10 Taris Biomedical Llc Methods of treating high-risk non-muscle invasive bladder cancer unresponsive to bacillus calmette-guérin therapy

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100330149A1 (en) * 2009-06-26 2010-12-30 Taris Biomedical, Inc. Solid Drug Tablets for Implantable Drug Delivery Devices
WO2012048104A1 (en) * 2010-10-06 2012-04-12 Taris Biomedical, Inc. Implantable drug delivery device with bladden retention feature
US8679094B2 (en) * 2009-12-17 2014-03-25 Taris Biomedical, Inc. Implantable device with intravesical tolerability and methods of treatment

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3967618A (en) * 1969-04-01 1976-07-06 Alza Corporation Drug delivery device
US4871542A (en) 1987-04-30 1989-10-03 Ferring Service Center, N.V. Method and apparatus useful for delivering medicinal compositions into the bladder and urinary tract
NZ228382A (en) * 1989-03-17 1992-08-26 Carter Holt Harvey Plastic Pro Drug administering coil-like device for insertion in body cavity of animal
FI95768C (fi) * 1993-06-17 1996-03-25 Leiras Oy Emättimensisäinen antosysteemi
US20060025726A1 (en) * 1996-06-04 2006-02-02 Vance Products Incorporated, D/B/A Cook Urological Incorporated Implantable medical device with pharmacologically active layer
US20060052757A1 (en) * 1996-06-04 2006-03-09 Vance Products Incorporated, D/B/A Cook Urological Incorporated Implantable medical device with analgesic or anesthetic
US20070161968A1 (en) * 1996-06-04 2007-07-12 Vance Products Inc., Dba Cood Urological Inc. Implantable medical device with pharmacologically active ingredient
WO1998043555A1 (en) 1997-04-03 1998-10-08 Point Biomedical Corporation Intravesical drug delivery system
US6183461B1 (en) 1998-03-11 2001-02-06 Situs Corporation Method for delivering a medication
US7077859B2 (en) 2000-12-22 2006-07-18 Avantec Vascular Corporation Apparatus and methods for variably controlled substance delivery from implanted prostheses
US6752829B2 (en) 2001-01-30 2004-06-22 Scimed Life Systems, Inc. Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same
MX2013000002A (es) * 2001-07-27 2013-04-29 Teva Womens Health Inc Metodos de tratamiento de condiciones patologicas asociadas con vejiga hiperactiva.
US8685427B2 (en) * 2002-07-31 2014-04-01 Boston Scientific Scimed, Inc. Controlled drug delivery
US7166133B2 (en) * 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
DE10247689A1 (de) 2002-10-12 2004-04-22 Martin Rahe Implantat in der Harnblase
US6926735B2 (en) 2002-12-23 2005-08-09 Scimed Life Systems, Inc. Multi-lumen vascular grafts having improved self-sealing properties
US7288084B2 (en) * 2003-04-28 2007-10-30 Boston Scientific Scimed, Inc. Drug-loaded medical device
DK1933810T3 (da) 2005-08-11 2013-01-28 Childrens Medical Center Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde
US20100003297A1 (en) 2005-08-11 2010-01-07 Massachusetts Institute Of Technology Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues
US20080311172A1 (en) * 2007-04-25 2008-12-18 Schapira Jay N Programmed-release, nanostructured biological construct
DK2231254T3 (da) 2007-12-11 2014-07-21 Massachusetts Inst Technology Implanterbar lægemiddelafgivelsesindretning
FI121000B (fi) * 2008-11-19 2010-06-15 Bayer Schering Pharma Oy Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi
US9017312B2 (en) * 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
PT2600800T (pt) 2010-08-05 2020-11-05 Taris Biomedical Llc Dispositivo de administração de drogas por stent ureteral, kit e método
PL3517101T3 (pl) 2010-08-05 2021-02-22 Taris Biomedical Llc Wszczepiane urządzenia do podawania leków w miejscach moczowo-płciowych
US8690840B2 (en) 2010-10-06 2014-04-08 Taris Biomedical, Inc. Time-selective bioresorbable or collapsible drug delivery systems and methods
WO2012106714A1 (en) 2011-02-04 2012-08-09 Taris Biomedical, Inc. Implantable device for controlled release of low solubility drug
MX357598B (es) 2011-07-20 2018-07-16 F Kiser Patrick Dispositivos intravaginales para administración de fármaco.
US10058688B2 (en) 2012-05-09 2018-08-28 Massachusetts Institute Of Technology Medicament, method, and drug delivery device for treatment of ovarian cancer
RU2651128C2 (ru) * 2012-05-19 2018-04-18 ТАРИС Биомедикал ЛЛК Имплантируемое урологическое устройство с улучшенной характеристикой извлечения
SG11201507294WA (en) 2013-03-15 2015-10-29 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
EP2968120A1 (en) 2013-03-15 2016-01-20 TARIS Biomedical LLC Drug delivery devices and methods for drug delivery
WO2015026813A1 (en) 2013-08-19 2015-02-26 Taris Biomedical Llc Multi-unit drug delivery devices and methods
WO2015175538A1 (en) 2014-05-12 2015-11-19 Taris Biomedical Llc Drug delivery devices and methods
WO2016172704A1 (en) 2015-04-23 2016-10-27 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100330149A1 (en) * 2009-06-26 2010-12-30 Taris Biomedical, Inc. Solid Drug Tablets for Implantable Drug Delivery Devices
US8679094B2 (en) * 2009-12-17 2014-03-25 Taris Biomedical, Inc. Implantable device with intravesical tolerability and methods of treatment
WO2012048104A1 (en) * 2010-10-06 2012-04-12 Taris Biomedical, Inc. Implantable drug delivery device with bladden retention feature

Also Published As

Publication number Publication date
EP4173615A2 (en) 2023-05-03
JP6856380B2 (ja) 2021-04-07
JP7005668B2 (ja) 2022-01-21
US11904123B2 (en) 2024-02-20
US20200368508A1 (en) 2020-11-26
AU2020250209A1 (en) 2020-11-05
WO2015200752A8 (en) 2016-08-11
EP4173615A3 (en) 2023-07-19
CN106456951A (zh) 2017-02-22
AU2015279674A1 (en) 2017-01-12
AU2022204523B2 (en) 2024-05-16
US12239807B2 (en) 2025-03-04
EP3517099B1 (en) 2022-12-28
CN106456951B (zh) 2021-11-05
EP3517099A1 (en) 2019-07-31
WO2015200752A1 (en) 2015-12-30
EP3160442A1 (en) 2017-05-03
US10737078B2 (en) 2020-08-11
AU2020250209B2 (en) 2022-07-14
US20200368509A1 (en) 2020-11-26
JP2020110615A (ja) 2020-07-27
KR102391761B1 (ko) 2022-04-27
EP3160442B1 (en) 2019-03-06
AU2022204523A1 (en) 2022-07-21
JP2017524421A (ja) 2017-08-31
ES2940478T3 (es) 2023-05-08
JP2022022292A (ja) 2022-02-03
KR20170026465A (ko) 2017-03-08
KR20220061253A (ko) 2022-05-12
AU2024204468A1 (en) 2024-07-18
KR20220061254A (ko) 2022-05-12
US20170165460A1 (en) 2017-06-15
CN114306899A (zh) 2022-04-12
KR20230142816A (ko) 2023-10-11
DK3160442T3 (da) 2019-06-11
ES2728504T3 (es) 2019-10-25
KR102486216B1 (ko) 2023-01-09

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