CN114306899A - 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法 - Google Patents

包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法 Download PDF

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Publication number
CN114306899A
CN114306899A CN202111310044.0A CN202111310044A CN114306899A CN 114306899 A CN114306899 A CN 114306899A CN 202111310044 A CN202111310044 A CN 202111310044A CN 114306899 A CN114306899 A CN 114306899A
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Prior art keywords
drug
lumen
silicone
elongated body
matrix system
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CN202111310044.0A
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English (en)
Chinese (zh)
Inventor
李喜真
卡伦·丹尼尔
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Liris Biomedical Inc
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Taris Biomedical Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0009Making of catheters or other medical or surgical tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00Methods of manufacture, assembly or production
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1078Urinary tract
    • A61M2210/1085Bladder

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
CN202111310044.0A 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法 Pending CN114306899A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462017775P 2014-06-26 2014-06-26
US62/017775 2014-06-26
CN201580033832.6A CN106456951B (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法
PCT/US2015/037887 WO2015200752A1 (en) 2014-06-26 2015-06-26 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201580033832.6A Division CN106456951B (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法

Publications (1)

Publication Number Publication Date
CN114306899A true CN114306899A (zh) 2022-04-12

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Application Number Title Priority Date Filing Date
CN201580033832.6A Active CN106456951B (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法
CN202111310044.0A Pending CN114306899A (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法

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Country Status (9)

Country Link
US (3) US10737078B2 (enExample)
EP (3) EP3160442B1 (enExample)
JP (3) JP6856380B2 (enExample)
KR (4) KR102486216B1 (enExample)
CN (2) CN106456951B (enExample)
AU (4) AU2015279674B2 (enExample)
DK (1) DK3160442T3 (enExample)
ES (2) ES2728504T3 (enExample)
WO (1) WO2015200752A1 (enExample)

Cited By (1)

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CN115120854A (zh) * 2022-07-04 2022-09-30 奥格生物技术(六安)有限公司 前列腺自然直接给药法

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US20180117219A1 (en) * 2015-04-29 2018-05-03 Northwestern University 3d printing of biomedical implants
WO2017132372A1 (en) * 2016-01-26 2017-08-03 Taris Biomedical Llc Multi-lumen drug delivery devices
CN118453872A (zh) 2016-05-06 2024-08-09 塔里斯生物医药公司 治疗下尿路尿道上皮癌的方法
JP7391009B2 (ja) 2017-07-25 2023-12-04 タリス バイオメディカル エルエルシー 腫瘍転移を処置する方法
US10792297B2 (en) 2017-11-08 2020-10-06 Taris Biomedical Llc Methods of treatment and maintenance therapy for bladder cancer using gemcitabine
US20190365645A1 (en) 2018-05-31 2019-12-05 Massachusetts Institute Of Technology Drug delivery articles for gram-level dosing
MX2021001264A (es) 2018-08-01 2021-07-02 Taris Biomedical Llc Métodos para tratar la vejiga hiperactiva con el uso de trospio.
MX2021005486A (es) * 2018-11-09 2021-06-18 Taris Biomedical Llc Dispositivos y sistemas de suministro de farmacos para el suministro local de farmacos al tracto urinario superior.
WO2022067197A1 (en) * 2020-09-28 2022-03-31 The Regents Of The University Of California Drug implants containing apalutamide and methods of use thereof
AU2022418527A1 (en) 2021-12-21 2024-08-08 Taris Biomedical Llc Urinary placement catheter for intravesical devices
WO2024092159A1 (en) 2022-10-28 2024-05-02 Taris Biomedical Llc Methods of treating bladder cancer with gemcitabine
KR20250168664A (ko) 2023-04-10 2025-12-02 타리스 바이오메디컬 엘엘씨 바실루스 칼메트-구에린 요법에 무반응성인 고위험 근육 비침습성 방광암을 치료하는 방법에 사용하기 위한 젬시타빈
TW202532086A (zh) 2023-10-02 2025-08-16 美商塔里斯生物醫學有限責任公司 治療對卡介苗療法無反應之高風險非肌肉侵襲性膀胱癌之方法

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US5062829A (en) * 1989-03-17 1991-11-05 Carter Holt Harvey Plastic Products Group Limited Relates to devices for administering a substance such as a drug or chemical or the like
US20060052757A1 (en) * 1996-06-04 2006-03-09 Vance Products Incorporated, D/B/A Cook Urological Incorporated Implantable medical device with analgesic or anesthetic
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US20040215169A1 (en) * 2003-04-28 2004-10-28 Scimed Life Systems, Inc. Drug-loaded medical device
US20080311172A1 (en) * 2007-04-25 2008-12-18 Schapira Jay N Programmed-release, nanostructured biological construct
US20090149833A1 (en) * 2007-12-11 2009-06-11 Massachusetts Institute Of Technology Implantable Drug Delivery Device and Methods for Treatment of the Bladder and Other Body Vesicles or Lumens
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US20100331770A1 (en) * 2009-06-26 2010-12-30 Taris Biomedical, Inc. Implantable Drug Delivery Devices and Methods of Making the Same
CN102596174A (zh) * 2009-09-10 2012-07-18 塔里斯生物医药公司 用于受控的药物递送的可植入装置
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115120854A (zh) * 2022-07-04 2022-09-30 奥格生物技术(六安)有限公司 前列腺自然直接给药法
CN115120854B (zh) * 2022-07-04 2023-10-13 奥格生物技术(六安)有限公司 前列腺自然直接给药装置

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EP3160442A1 (en) 2017-05-03
KR20170026465A (ko) 2017-03-08
JP7005668B2 (ja) 2022-01-21
KR102391761B1 (ko) 2022-04-27
EP4173615A2 (en) 2023-05-03
WO2015200752A1 (en) 2015-12-30
AU2015279674B2 (en) 2020-07-23
AU2022204523B2 (en) 2024-05-16
KR102486216B1 (ko) 2023-01-09
AU2020250209B2 (en) 2022-07-14
AU2020250209A1 (en) 2020-11-05
EP3517099A1 (en) 2019-07-31
CN106456951B (zh) 2021-11-05
US20200368508A1 (en) 2020-11-26
US12239807B2 (en) 2025-03-04
JP2017524421A (ja) 2017-08-31
EP3160442B1 (en) 2019-03-06
WO2015200752A8 (en) 2016-08-11
AU2024204468A1 (en) 2024-07-18
US20200368509A1 (en) 2020-11-26
EP3517099B1 (en) 2022-12-28
KR20230142816A (ko) 2023-10-11
JP2022022292A (ja) 2022-02-03
AU2015279674A1 (en) 2017-01-12
US20170165460A1 (en) 2017-06-15
US11904123B2 (en) 2024-02-20
JP6856380B2 (ja) 2021-04-07
ES2728504T3 (es) 2019-10-25
KR20220061254A (ko) 2022-05-12
AU2022204523A1 (en) 2022-07-21
DK3160442T3 (da) 2019-06-11
KR20220061253A (ko) 2022-05-12
JP2020110615A (ja) 2020-07-27
US10737078B2 (en) 2020-08-11
ES2940478T3 (es) 2023-05-08
CN106456951A (zh) 2017-02-22
EP4173615A3 (en) 2023-07-19

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