ES2940478T3 - Dispositivos de administración de fármacos intravesicales y métodos que incluyen sistemas de matriz de polímero-fármaco elásticos - Google Patents
Dispositivos de administración de fármacos intravesicales y métodos que incluyen sistemas de matriz de polímero-fármaco elásticos Download PDFInfo
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- ES2940478T3 ES2940478T3 ES19158984T ES19158984T ES2940478T3 ES 2940478 T3 ES2940478 T3 ES 2940478T3 ES 19158984 T ES19158984 T ES 19158984T ES 19158984 T ES19158984 T ES 19158984T ES 2940478 T3 ES2940478 T3 ES 2940478T3
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- GOZBHBFUQHMKQB-UHFFFAOYSA-N trimecaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=C(C)C=C1C GOZBHBFUQHMKQB-UHFFFAOYSA-N 0.000 description 1
- 229950002569 trimecaine Drugs 0.000 description 1
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 1
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- 229930004668 tropane alkaloid Natural products 0.000 description 1
- 150000003813 tropane derivatives Chemical class 0.000 description 1
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- 230000036318 urination frequency Effects 0.000 description 1
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- A61K9/0012—Galenical forms characterised by the site of application
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0009—Making of catheters or other medical or surgical tubes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0216—Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1078—Urinary tract
- A61M2210/1085—Bladder
Landscapes
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- Veterinary Medicine (AREA)
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- Dermatology (AREA)
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- Media Introduction/Drainage Providing Device (AREA)
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| ES15734801T Active ES2728504T3 (es) | 2014-06-26 | 2015-06-26 | Dispositivos de administración de fármacos por vía intravesical y métodos que comprenden sistemas matriciales polímero-fármaco elásticos |
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| WO2016176444A1 (en) * | 2015-04-29 | 2016-11-03 | Northwestern University | 3d printing of biomedical implants |
| WO2017132372A1 (en) | 2016-01-26 | 2017-08-03 | Taris Biomedical Llc | Multi-lumen drug delivery devices |
| NZ748252A (en) | 2016-05-06 | 2025-10-31 | Taris Biomedical Llc | Method of treating lower tract urothelial cancer |
| SG10201913998YA (en) | 2017-07-25 | 2020-03-30 | Taris Biomedical Llc | Methods of treating tumor metastasis |
| MX2020004771A (es) | 2017-11-08 | 2020-10-19 | Taris Biomedical Llc | Metodos de tratamiento y terapia de mantenimiento para el cancer de vejiga con gemcitabina. |
| US20190365645A1 (en) | 2018-05-31 | 2019-12-05 | Massachusetts Institute Of Technology | Drug delivery articles for gram-level dosing |
| CN112839653A (zh) | 2018-08-01 | 2021-05-25 | 塔里斯生物医药公司 | 使用曲司氯铵治疗膀胱过度活动症的方法 |
| SG11202103505YA (en) * | 2018-11-09 | 2021-05-28 | Taris Biomedical Llc | Drug delivery devices and systems for local drug delivery to the upper urinary tract |
| US20240016731A1 (en) * | 2020-09-28 | 2024-01-18 | The Regents Of The University Of California | Drug Implants Containing Apalutamide and Methods of Use Thereof |
| TW202339815A (zh) | 2021-12-21 | 2023-10-16 | 美商塔里斯生物醫學有限責任公司 | 用於膀胱內裝置的泌尿置放導管 |
| CN115120854B (zh) * | 2022-07-04 | 2023-10-13 | 奥格生物技术（六安）有限公司 | 前列腺自然直接给药装置 |
| US20240033249A1 (en) * | 2022-07-20 | 2024-02-01 | The Regents Of The University Of California | Drug Implants Containing Darolutamide and Methods of Use Thereof |
| WO2024092159A1 (en) | 2022-10-28 | 2024-05-02 | Taris Biomedical Llc | Methods of treating bladder cancer with gemcitabine |
| AU2024249710A1 (en) | 2023-04-10 | 2025-11-20 | Taris Biomedical Llc | Gemcitabine for use in methods of treating high-risk non-muscle invasive bladder cancer unresponsive to bacillus calmette-guerin therapy |
| WO2025076007A1 (en) | 2023-10-02 | 2025-04-10 | Taris Biomedical Llc | Methods of treating high-risk non-muscle invasive bladder cancer unresponsive to bacillus calmette-guérin therapy |
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| US3854480A (en) * | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| US3967618A (en) * | 1969-04-01 | 1976-07-06 | Alza Corporation | Drug delivery device |
| US4871542A (en) | 1987-04-30 | 1989-10-03 | Ferring Service Center, N.V. | Method and apparatus useful for delivering medicinal compositions into the bladder and urinary tract |
| NZ228382A (en) * | 1989-03-17 | 1992-08-26 | Carter Holt Harvey Plastic Pro | Drug administering coil-like device for insertion in body cavity of animal |
| FI95768C (fi) * | 1993-06-17 | 1996-03-25 | Leiras Oy | Emättimensisäinen antosysteemi |
| US20060025726A1 (en) * | 1996-06-04 | 2006-02-02 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Implantable medical device with pharmacologically active layer |
| US20060052757A1 (en) * | 1996-06-04 | 2006-03-09 | Vance Products Incorporated, D/B/A Cook Urological Incorporated | Implantable medical device with analgesic or anesthetic |
| US20070161968A1 (en) * | 1996-06-04 | 2007-07-12 | Vance Products Inc., Dba Cood Urological Inc. | Implantable medical device with pharmacologically active ingredient |
| KR20010006027A (ko) | 1997-04-03 | 2001-01-15 | 포인트 바이오메디칼 코퍼레이션 | 방광내 약물 송달 시스템 |
| US6183461B1 (en) | 1998-03-11 | 2001-02-06 | Situs Corporation | Method for delivering a medication |
| US7077859B2 (en) | 2000-12-22 | 2006-07-18 | Avantec Vascular Corporation | Apparatus and methods for variably controlled substance delivery from implanted prostheses |
| US6752829B2 (en) | 2001-01-30 | 2004-06-22 | Scimed Life Systems, Inc. | Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same |
| MX2013000002A (es) * | 2001-07-27 | 2013-04-29 | Teva Womens Health Inc | Metodos de tratamiento de condiciones patologicas asociadas con vejiga hiperactiva. |
| US8685427B2 (en) * | 2002-07-31 | 2014-04-01 | Boston Scientific Scimed, Inc. | Controlled drug delivery |
| US7166133B2 (en) * | 2002-06-13 | 2007-01-23 | Kensey Nash Corporation | Devices and methods for treating defects in the tissue of a living being |
| DE10247689A1 (de) | 2002-10-12 | 2004-04-22 | Martin Rahe | Implantat in der Harnblase |
| US6926735B2 (en) | 2002-12-23 | 2005-08-09 | Scimed Life Systems, Inc. | Multi-lumen vascular grafts having improved self-sealing properties |
| US7288084B2 (en) * | 2003-04-28 | 2007-10-30 | Boston Scientific Scimed, Inc. | Drug-loaded medical device |
| DK1933810T3 (da) | 2005-08-11 | 2013-01-28 | Childrens Medical Center | Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde |
| US20080311172A1 (en) * | 2007-04-25 | 2008-12-18 | Schapira Jay N | Programmed-release, nanostructured biological construct |
| DK2231254T3 (da) * | 2007-12-11 | 2014-07-21 | Massachusetts Inst Technology | Implanterbar lægemiddelafgivelsesindretning |
| CA2733468C (en) | 2008-08-09 | 2017-12-05 | Massachusetts Institute Of Technology | Implantable drug delivery device and methods of treating male genitourinary and surrounding tissues |
| FI121000B (fi) * | 2008-11-19 | 2010-06-15 | Bayer Schering Pharma Oy | Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi |
| EA023156B1 (ru) * | 2009-06-26 | 2016-04-29 | ТАРИС Биомедикал ЛЛК | Устройство для доставки лекарств |
| US9017312B2 (en) * | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| DK2512581T3 (da) * | 2009-12-17 | 2021-03-29 | Taris Biomedical Llc | Implanterbar indretning med intravesikal tolerance |
| EP2600800B1 (en) | 2010-08-05 | 2020-09-30 | TARIS Biomedical LLC | Ureteral stent drug delivery device and kit |
| HUE051942T2 (hu) | 2010-08-05 | 2021-03-29 | Taris Biomedical Llc | Implantálható gyógyszerszállító készülékek genitourinális szervekhez |
| JP5945544B2 (ja) * | 2010-10-06 | 2016-07-05 | タリス バイオメディカル エルエルシー | 時間選択的に生体吸収可能または崩壊可能な薬剤送達システムおよび方法 |
| WO2012048104A1 (en) * | 2010-10-06 | 2012-04-12 | Taris Biomedical, Inc. | Implantable drug delivery device with bladden retention feature |
| BR112013019410A2 (pt) | 2011-02-04 | 2019-09-24 | Taris Biomedical Inc | dispositivo implantável para liberação controlada de fármaco de solubilidade baixa |
| EP2734262B1 (en) | 2011-07-20 | 2018-02-28 | Patrick F. Kiser | Intravaginal rings for drug delivery |
| WO2013170069A1 (en) | 2012-05-09 | 2013-11-14 | Massachusetts Institute Of Technology | Medicament, method, and drug delivery device for treatment of ovarian cancer |
| MX370368B (es) * | 2012-05-19 | 2019-12-11 | Taris Biomedical Llc | Dispositivo urologico implantable con caracteristica de extraccion mejorada. |
| PT2968880T (pt) | 2013-03-15 | 2025-07-07 | Taris Biomedical Llc | Dispositivos de aplicação de fármaco com componente permeável a fármaco |
| AU2014227914B2 (en) | 2013-03-15 | 2018-05-10 | Taris Biomedical Llc | Drug delivery devices and methods for drug delivery |
| KR102503010B1 (ko) | 2013-08-19 | 2023-02-24 | 타리스 바이오메디컬 엘엘씨 | 다중 유닛 약물 전달 장치 및 방법 |
| EP3142740B1 (en) | 2014-05-12 | 2020-12-02 | TARIS Biomedical LLC | Drug delivery devices |
| JP7425534B2 (ja) | 2015-04-23 | 2024-01-31 | タリス バイオメディカル エルエルシー | 薬物透過性構成要素を有する薬物送達デバイス及び方法 |
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2015
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