CN106421543B - A kind of Chinese medicine composition and preparation method thereof for treating cough - Google Patents

Abstract

The present invention relates to a kind of Chinese medicine compositions and preparation method thereof for treating cough.The Chinese medicine composition is prepared by following Chinese medicine material: radix scutellariae, almond, campanulaceae, Chinese yam, perilla seed, terminalia flesh, radish seed, viola mandshurica, charred FRUCTUS CRATAEGI, malt, rice sprout, Divine Comedy.The Chinese medicine composition has clearing heat and detoxicating, relieving cough and reducing sputum effect, cures mainly phlegm-heat cough, deficiency of food.

Description

A kind of Chinese medicine composition and preparation method thereof for treating cough

Technical field

The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition and preparation method thereof for treating cough.

Background technique

Cough refers to the factors such as exogenous disease or internal injury, causes lung to lose and declares respectful, Lung Qi upward reversal, impact air flue, issues cough sound or companion It coughs up phlegm as a kind of disease of Clinical symptoms.Sound no phlegm is known as cough by the successive dynasties, has phlegm is noiseless to be known as coughing, there is the cough of the sound meaning of phlegm It coughs.Clinically be mostly phlegm sound and to see, be difficult it is well-separated, therefore to cough and claim.Cough is both disease and the lung system of independence One symptom of a variety of diseases.

Cough is one of disease most commonly seen in internal medicine, and disease incidence is very high, and the disease incidence of chronic cough is according to statistics 3%-5%, the disease incidence in the elderly are especially higher with cold district disease incidence up to 10% -15%.Traditional Chinese medical herbal treatment Cough has greater advantage, has accumulated Couple herbs abundant.

The problems such as "Nei Jing" is lapsed to and treated to the origin cause of formation of cough, symptom and syndrome-classification, syndrome has been made compared with system It discusses, elaborates that climate change, six gas influence and lung can be so that cough, such as " Plain Questions declares five gas " be said: " five kinds of diseases caused by disorders of ZANG-QI ... Disorder of the lung giving rise to cough." " Plain Questions cough opinion " be even more one discuss cough a special piece, it is indicated that " vital organs of the human body all make us cough, non-only lung." strong Adjust lungs that can be led to the generation of cough by evil and visceral dysfunction.Classify to the symptom of cough by internal organs, point For lung cough, heart cough, stomach cough, cough with incontirence of urine etc., and indicate that syndrome lapses to and principle of reatment.The Chinese, " gold of treatise on Febrile Diseases written by Zhang Zhongjing Deficient outline " the effective prescription of many treatments coughs has not only been drawn up, the thought that diagnosis and treatment is carried out to cough is also presented.

Cough divides exogenous cough and endogenous cough, and exogenous cough's cause of disease is the heresy of the exogenous disease six external factors which cause diseases；Endogenous cough's cause of disease is drink The internal injuries factors such as food, feelings will cause visceral dysfunction, interior sick heresy.Exogenous cough and endogenous cough are that disease and evil causes lung qi Unclear mistake Yu Xuansu compels gas superinverse and makees cough.The sick position of cough, it is main dirty in lung, no matter the disease and evil that the exogenous disease six external factors which cause diseases or internal injury are given birth to, It all invades and causes to cough in lung.

The treatment of cough should distinguish evil positive actual situation.Exogenous cough stops up lung, mostly real example for perverse trend, therefore is with eliminating evil benefit lung Dispelling wind, cold dispelling, heat-clearing, dryness-moistruizing and treating should be respectively adopted according to perverse trend chill, wind-heat, the difference of wind-dryness in principle of reatment.Internal injury Cough, more category dominations of pathogen are weakened body resistance, therefore with eliminating pathogen to support vital qi, giving consideration to both the incidental and fundamental is principle of reatment, is " phlegm " and " fire ", eliminating evil point according to disease and evil Weight phlegm is not used, is relieved inflammation or internal heat to control, and weakened body resistance, yin-nourishing or QI invigorating are advisable, and should distinguish the processing of actual situation primary and secondary.

The treatment of cough, in addition to directly controlling lung, spleen should be also controlled from entirety attention, liver is controlled, controls kidney etc..Exogenous cough one As avoid hold back it is puckery stay heresy, when making the best use of the situation, the smooth then cough of lung qi of waiting a surname is from only；Endogenous cough should anti-surname dissipate wound just, pays attention to improving Internal organs care for shield healthy tendency.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine compositions for treating cough；

It is a further object of the present invention to provide a kind of Chinese medicine composition preparation methods for treating cough.

The object of the present invention is achieved by the following technical solutions:

The Chinese medicine composition for the treatment of cough of the present invention, it is by including that the raw material of following parts by weight is prepared :

2-30 parts of radix scutellariae, 2-30 parts of almond, 2-30 parts of campanulaceae, 2-30 parts of Chinese yam, 2-30 parts of perilla seed, terminalia flesh 2-30 Part, 2-30 parts of radish seed, 10-50 parts of viola mandshurica, 1-15 parts of charred FRUCTUS CRATAEGI, 1-15 parts of malt, 1-15 parts of rice sprout, Divine Comedy 1-15 Part.

Preferably, it is by including that the raw material of following parts by weight is prepared:

4-20 parts of radix scutellariae, 4-20 parts of almond, 4-20 parts of campanulaceae, 4-20 parts of Chinese yam, 4-20 parts of perilla seed, terminalia flesh 4-20 Part, 4-20 parts of radish seed, 15-40 parts of viola mandshurica；1-10 parts of charred FRUCTUS CRATAEGI, 1-10 parts of malt, 1-10 parts of rice sprout, Divine Comedy 1-10 Part.

It is the crude drug source of the traditional chinese medicine composition of the invention below:

Radix scutellariae is the dry root of Lamiaceae plant radix scutellariae Scutellaria baicalensis Georgi.[nature and flavor] Hardship is trembled with fear.[channel tropism] return lung, gallbladder, spleen, large intestine, small intestinl channel.[major function] heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention.With In damp-warm syndrome, heat temperature chest tightness and emesis, damp and hot feeling of fullness, dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, tire Dynamic uneasiness.

Almond is the dry seed of the bitters such as rosaceous plant apricot or ansu apricot.[nature and flavor] are bitter, temperature, toxic.[channel tropism] enters Lung, large intestine channel.[major function] expelling phlegm and arresting coughing, relievings asthma, ease constipation.Exogenous cough is controlled, asthma is full, sore throat, dry constipation of intestines.

Campanulaceae, for the dry root of Campanulaceae campanulaceae Platycodon grandiflorum(Jacq.) A.DC..[property Taste] it is bitter, pungent, it puts down.[channel tropism] is distributed in lung channel.[major function] promoting the dispersing function of the lung, relieving sore-throat, eliminating the phlegm, apocenosis.For coughing with a lot of sputum, it is uncomfortable in chest not Freely, pharyngalgia, hoarse voice, lung carbuncle pyemesis, sore purulence is not at bursting.

Chinese yam is the dry rhizome of Dioscoreaceae plant Chinese yam Dioscorea opposita Thunb..[nature and flavor] are sweet, It is flat.[channel tropism] returns spleen, lung, kidney channel.[major function] tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying arresting seminal emission.For spleen eating less, long It rushes down incessantly, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, leukorrhagia, frequent micturition, and abnormal heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) good efficacy to suffering from a deficiency of the kidney.For spleen eating less, let out Rush down loose stool, leukorrhea.

Perilla seed is the dry mature fruit of Lamiaceae plant purple perilla Perilla frutescens (L.) Britt.. [nature and flavor] are acrid in flavour and warm in nature.[channel tropism] is distributed in lung channel.[major function] sending down abnormally ascending dissolving phlegm, relievings asthma, ease constipation.For phlegm stops up the circulation of vital energy in the wrong direction, gas of coughing Asthma, dry constipation of intestines.

Terminalia flesh, combretaceae plant myrobalan Terminalia chebula Retz. or villus myrobalan The dry mature fruit of Terminalia chebula Retz. var. tomentella Kurt. is cleaned, is slightly soaked, bored profit, Stoning, it is dry to be made.[nature and flavor] are bitter, sour, puckery, put down.[channel tropism] return lung, large intestine channel.[major function] puckery intestines astringing lung-QI, fall fire Relieving sore-throat.For protracted dysentery and diarrhea, hematochezia rectal prolapse, the deficiency syndrome of the lung is breathed with cough, and is coughed long more than, pharyngalgia hoarse voice.

Radish seed is the dry mature seed of crucifer radish Raphanus sativus L..[nature and flavor] pungent, Sweet and neutral.[channel tropism] return lung, spleen, stomach meridian.[major function] help digestion and eliminate flatulence, lowering the adverse-rising QI to resolve phlegm.For retention of food and drink, abdominal distention, Constipation, stagnation and diarrhea, phlegm choking, dyspnea and cough.

Viola mandshurica is the drying herb of violaceae plant viola mandshurica Viola yedoensis Makino.[nature and flavor] Bitter, acrid, cold.[channel tropism] converge to heart and liver channels.[major function] is clearing heat and detoxicating, cool blood detumescence.For furuncle swelling toxin, ulcer carbuncle on the back, Erysipelas, venomous snake bite.

Charred FRUCTUS CRATAEGI is rosaceous plant large-fruited Chinese hawthorn Crataegus pinnatifida Bge.var.major N.E.Br. Or the dry mature fruit of hawthorn Crataegus pinnatifida Bge., slice is cleaned, is put in pot, is fried brown to surface coke Color, internal yellowish-brown.[nature and flavor] sour, sweet, tepor.[channel tropism] returns spleen, stomach, Liver Channel.[major function] promoting digestion effect increases By force.For meat stagnation, dysentery is not well.

Malt, the ripening fruits for gramineae plant barley Hordeum vulgare L. is dry through germination and obtains.[property Taste] sweet and neutral.[channel tropism] returns spleen, stomach meridian.[major function] promoting the circulation of qi helps digestion, spleen benefiting and stimulating the appetite, moves back newborn dissipate-swelling.Not for dyspepsia Disappear, abdominal distention, spleen eating less, milk smoulders, swollen breasts, weaning women.

Rice sprout, the ripening fruits for being gramineae plant grain Setaria italica (L.) Beauv. it is dry through germination and ?.[nature and flavor] sweet, warm.[channel tropism] returns spleen, stomach meridian.[major function] helps digestion in, spleen benefiting and stimulating the appetite.For dyspepsia, abdomen Swollen halitosis, weakness of the spleen and the stomach, not hungry deficiency of food.

Divine Comedy is after the medicines such as polygonum flaccidum, sweet wormwood, almond are added flour or wheat bran mixes, it is fermented made of herbal leaven.[nature and flavor] Sweet, acrid, warm.[channel tropism] enters spleen, stomach meridian.[major function] strengthening the spleen and stomach, in the tune that helps digestion.Retention of food and drink is controlled, feeling of stuffiness in chest abdominal distension is vomitted Vomiting and diarrhoea dysentery, postpartum blood stasis abdominal pain, the big hard product of children's abdomen.

There is provided the preparation method of the active constituent of the traditional chinese medicine composition of the invention, this method to be for another aspect of the present invention It is mentioned using use water or the extraction of the ethyl alcohol of 40-80% concentration expressed in percentage by volume is prepared.It is specific the preparation method is as follows:

Scheme one: taking 12 taste medicinal materials, and extracting in water 2-3 times after mixing, each amount of water is equivalent to the 6- of medicinal material total weight 12 times, each extraction time is 1-3 hours, and combined extract, filtration, relative density is when filtrate is concentrated into 70-80 DEG C 1.15-1.20 clear cream to get active constituent.

Scheme two: taking 12 taste medicinal materials, is extracted 2-3 times after mixing with 40-80% alcohol reflux, and each ethanol consumption is medicinal material 4-10 times of total amount, extraction time are 1-4 hours, and combined extract, filtering, relative density is when filtrate is concentrated into 70-80 DEG C 1.15-1.20 clear cream to get active constituent.

Scheme three: taking 12 taste medicinal materials, and extracting in water 2-3 times after mixing, each amount of water is equivalent to the 6- of medicinal material total weight 12 times, each extraction time is 1-3 hours, combined extract, filtration, and relative density is 1.15- when filtrate is concentrated into 70-80 DEG C Ethyl alcohol is added in 1.20 clear cream, makes alcohol content 40-70%, stands 12-24 hours, and filtration, filtrate is concentrated into 70-80 DEG C of phase To the medicinal extract that density is 1.10-1.25 to get active constituent.

The Chinese medicine composition for the treatment of cough of the present invention can also be made with pharmaceutically acceptable carrier combination At various oral preparations, such as tablet, capsule, oral solution, syrup, mixture.

Pharmaceutically acceptable carrier of the invention includes but is not limited to following:

Oral preparation:

Diluent: starch, Icing Sugar, lactose, dextrin, microcrystalline cellulose, inorganic salts, glycitols etc..

Wetting agent and adhesive: purified water, ethyl alcohol, gelatin, polyethylene glycol, cellulose derivative etc..

Disintegrating agent: starch, sodium carboxymethyl starch, cellulose derivative, crospovidone etc..

Lubricant: magnesium stearate, superfine silica gel powder, talcum powder, polyethylene glycol etc..

Cosolvent: water, ethyl alcohol, glycerol, propylene glycol, liquid paraffin, vegetable oil etc..

Corrigent: sucrose, monosaccharide, aromatic etc..

Preservative: benzoic acid, sorbic acid, methyl esters, ethyl ester, propyl ester etc..

Method 1: tablet

It takes scheme one one of to three gained active constituent of scheme, tablet is added and often uses auxiliary material, routinely prepared by production method Obtain Tablets.

Above-mentioned tablet often includes one of diluent, wetting agent, adhesive, disintegrating agent, lubricant or whole with auxiliary material.

Method 1: capsule

It takes scheme one one of to three gained active constituent of scheme, capsule is added and often uses auxiliary material, routinely producer legal system It is standby to obtain capsule of the present invention.

Above-mentioned capsule often includes one of diluent, wetting agent, adhesive, disintegrating agent, lubricant or whole with auxiliary material.

Method 3: syrup

It takes scheme one one of to three gained active constituent of scheme, syrup is added and often uses auxiliary material, routinely producer legal system It is standby to obtain syrup of the present invention.

Above-mentioned syrup often includes one of corrigent, preservative, cosolvent or whole with auxiliary material.

Method 4: mixture

It takes scheme one one of to three gained active constituent of scheme, mixture is added and often uses auxiliary material, routinely prepared by production method Obtain mixture of the present invention.

Above-mentioned mixture often includes one of corrigent, preservative or whole with auxiliary material.

Method 5: oral solution

Take scheme one one of to three gained active constituent of scheme, dissolution after-purification, concentration are added oral solution and often use auxiliary material, Routinely production method is prepared into oral solution of the present invention.

Above-mentioned oral solution often includes one of corrigent, preservative, cosolvent or whole with auxiliary material.

The applicant refers to modern pharmacological research achievement on the basis of studying Traditional Chinese Medicine Coryza Treated by Syndrome Differentiation, by many years Test, multiple formulations are screened, the Chinese medicine preparation that can effectively treat cough is had found, radix scutellariae clearing heat-fire in side controls lung Heat cough；Almond expelling phlegm and arresting coughing, controls exogenous cough；Campanulaceae promoting the dispersing function of the lung relieving sore-throat eliminating the phlegm is used for coughing with a lot of sputum；Chinese yam benefit lung fluid is used In deficiency syndrome of the lung cough and asthma；Perilla seed sending down abnormally ascending dispelling phlegm to stop asthma is used for phlegm stops up the circulation of vital energy in the wrong direction, cough and asthma；Terminalia flesh astringing lung-QI fall fire is breathed heavily for the deficiency syndrome of the lung Cough is coughed more than long；Radish seed lowering the adverse-rising QI to resolve phlegm is used for phlegm choking, dyspnea and cough；It is clearing heat and detoxicating to be aided with viola mandshurica, charred FRUCTUS CRATAEGI, malt, paddy Bud, Divine Comedy strengthening the spleen and stomach, for stomach Qi rising, transmitting and distributing the fluids function reduction leads to coughing with a lot of sputum caused by unsmoothness of pulmonary qi.Quan Fang Mutually collaboration has clearing heat and detoxicating, relieving cough and reducing sputum effect, cures mainly phlegm-heat cough, deficiency of food.

A kind of Chinese medicine composition for treating cough provided by the invention has the advantage that

1, composite preparation provided by the invention is safe and effective, has clearing heat and detoxicating, relieving cough and reducing sputum effect, cures mainly phlegm heat Cough, deficiency of food.

2, clinical tests prove that, healing of the patient after traditional Chinese medicine composition for treating of the present invention, to branch phlegm-heat cough Rate is 48.8%, total effective rate 90.7%.

3, Chinese medicinal composition preparation provided by the invention, formula is scientific and reasonable, simple process, in good taste, at low cost.

Specific embodiment

The present invention is further illustrated below by embodiment.It should be understood that the embodiment of the present invention is for illustrating The present invention is rather than limiting the invention.The simple modifications that essence according to the present invention carries out the present invention belong to the present invention Claimed range.Unless otherwise indicated, the percentage of the amount of alcohol in the present invention is percentage by volume, and v/v indicates solution Volume ratio.

1 tablet of embodiment

Weigh radix scutellariae 0.2kg, almond 0.2kg, campanulaceae 0.2kg, Chinese yam 0.2kg, perilla seed 0.2kg, terminalia flesh 0.2kg, Radish seed 0.2kg, viola mandshurica 1kg, charred FRUCTUS CRATAEGI 0.1kg, malt 0.1kg, rice sprout 0.1kg, Divine Comedy 0.1kg.Extracting in water 3 Secondary, amount of water is respectively 12 times of medicinal material total weight, 8 times, 6 times three times, three times extraction time be respectively 3 hours, 2 hours, it is 1 small When, combined extract, filtration, the clear cream that relative density is 1.25 when filtrate is concentrated into 70 DEG C, addition supplementary product starch, ethyl alcohol, cunning Tablet is made in mountain flour.

2 tablet of embodiment

Radix scutellariae 3kg, almond 3kg, campanulaceae 3kg, Chinese yam 3kg, perilla seed 3kg, terminalia flesh 3kg, radish seed 3kg are weighed, it is purple Flower Chinese violet 5kg, charred FRUCTUS CRATAEGI 1.5kg, malt 1.5kg, rice sprout 1.5kg, Divine Comedy 1.5kg.With 40% alcohol reflux extract 3 times, every time Ethanol consumption is respectively 10 times of medicinal material total amount, 8 times, 4 times, and extraction time distinguishes 3 hours, 2 hours, 1 hour, merges and extracts Supplementary product starch, ethyl alcohol, talcum powder is added in liquid, filtering, the medicinal extract that relative density is 1.25 when filtrate is concentrated 60 DEG C, and tablet is made.

3 granule of embodiment

Weigh radix scutellariae 1kg, almond 1.2kg, campanulaceae 0.8kg, Chinese yam 0.5kg, perilla seed 2kg, terminalia flesh 1.5kg, radish Sub- 0.8kg, viola mandshurica 1.2kg, charred FRUCTUS CRATAEGI 0.5kg, malt 0.5kg, rice sprout 0.5kg, Divine Comedy 0.5kg.Extracting in water 3 times, Amount of water is respectively equivalent to 12 times of medicinal material total weight, 8 times, 6 times three times, each extraction time distinguish 3 hours, 2 hours, it is 1 small When, combined extract, filtration, relative density is 1.20 clear cream when filtrate is concentrated into 70 DEG C, and ethyl alcohol is added, makes alcohol content 40%, stand 24 hours, filtration, filtrate is concentrated into the medicinal extract that relative density when filtrate is concentrated into 70 DEG C is 1.10, be added starch, Dextrin, granulation, dry, whole grain to obtain the final product.

4 capsule of embodiment

Radix scutellariae 2kg, almond 2kg, campanulaceae 2kg, Chinese yam 2kg, perilla seed 2kg, terminalia flesh 2kg, radish seed 2kg are weighed, it is purple Flower Chinese violet 4kg, charred FRUCTUS CRATAEGI 1kg, malt 1kg, rice sprout 1kg, Divine Comedy 1kg.It is extracted 2 times with alcohol reflux, each concentration of alcohol point Not Wei 80%, 60%, each ethanol consumption is respectively 10 times of medicinal material total amount, 8 times, and extraction time is respectively 4 hours, 3 hours, is closed And extracting solution, filtering, when filtrate is concentrated into 80 DEG C relative density be 1.10 medicinal extract, in medicinal extract be added supplementary product starch, ethyl alcohol, Dextrin, magnesium stearate, are made capsule according to a conventional method.

5 oral solution of embodiment

Weigh radix scutellariae 0.4kg, almond 0.4kg, campanulaceae 0.4kg, Chinese yam 0.4kg, perilla seed 0.4kg, terminalia flesh 0.4kg, Radish seed 0.4kg, viola mandshurica 1.5kg, charred FRUCTUS CRATAEGI 0.1kg, malt 0.1kg, rice sprout 0.1kg, Divine Comedy 0.1kg.Extracting in water 2 Secondary, amount of water is respectively 10 times of medicinal material total weight, 8 times twice, and extraction time is respectively 2 hours, 1 hour twice, and merging mentions Take liquid, filter, when filtrate is concentrated into 80 DEG C relative density be 1.10 medicinal extract, in medicinal extract be added auxiliary material mannitol, sorbic acid, Water stirs evenly, and oral solution is made in packing.

6 granule of embodiment

Weigh radix scutellariae 2.5kg, almond 1.5kg, campanulaceae 2kg, Chinese yam 1.8kg, perilla seed 2.5kg, terminalia flesh 0.8kg, Lay Fu 0.5kg, viola mandshurica 3kg, charred FRUCTUS CRATAEGI 1.2kg, malt 0.5kg, rice sprout 1kg, Divine Comedy 0.8kg.Extracting in water 2 times, often Secondary amount of water is respectively equivalent to 12 times of medicinal material total weight, 10 times, and each extraction time is respectively 3 hours, 2 hours, and merging mentions Liquid is taken, is filtered, filtrate is concentrated into the clear cream that relative density is 1.05 at 80 DEG C, and ethyl alcohol is added, and makes alcohol content 70%, stands 12 Hour, starch, dextrin is added in filtration, the medicinal extract that relative density is 1.25 when filtrate is concentrated into 70 DEG C, and granulation, dry, whole grain are ?.

7 syrup of embodiment

Weigh radix scutellariae 1.5kg, almond 1.2kg, campanulaceae 2.8kg, Chinese yam 0.5kg, perilla seed 1.2kg, terminalia flesh 1.5kg, Radish seed 2kg, viola mandshurica 2.5kg, charred FRUCTUS CRATAEGI 0.3kg, malt 0.5kg, rice sprout 0.5kg, Divine Comedy 0.3kg.Extracting in water 2 Secondary, amount of water is respectively 10 times of medicinal material total weight, 8 times twice, and extraction time is respectively 2 hours, 1 hour twice, and merging mentions Liquid is taken, is filtered, the medicinal extract that relative density is 1.10 when filtrate is concentrated into 80 DEG C.Syrup auxiliary material sucrose, mountain are added in medicinal extract Pears acid, water stir evenly, and syrup is made.

8 mixture of embodiment

Radix scutellariae 2kg, almond 2kg, campanulaceae 2kg, Chinese yam 2kg, perilla seed 2kg, terminalia flesh 2kg, radish seed 2kg are weighed, it is purple Flower Chinese violet 3.5kg, charred FRUCTUS CRATAEGI 0.5kg, malt 0.5kg, rice sprout 0.5kg, Divine Comedy 0.5kg.Extracting in water 3 times, amount of water three times 12 times, 8 times, 6 times of medicinal material total weight are respectively equivalent to, each extraction time distinguishes 3 hours, 2 hours, 1 hour, merges and extracts Liquid, filtration, 3 times that ad pond om is medicinal material total weight are concentrated in filtrate, filling, and mixture auxiliary material sucrose, ethyl ester, water, sorb is added Acid stirs evenly, and mixture is made.

9 pulvis of embodiment

Weigh radix scutellariae 2.5kg, almond 2kg, campanulaceae 2kg, Chinese yam 1.8kg, perilla seed 1.2kg, terminalia flesh 1.5kg, radish Sub- 2kg, viola mandshurica 3kg, charred FRUCTUS CRATAEGI 1kg, malt 1kg, rice sprout 1kg, Divine Comedy 1kg.Crush, sieving to get.

Clinical test

One, to the clinical observation of phlegm-heat cough patient

1 general information

Observe 86 cough patients.Women 38 in 86 patients, male 48, the range of age: 18~55 years old.

2 diagnostic criteria

Primary symptom: 1, it coughs not well；2, phlegm is turbid sticky or yellow；3, red tongue body, yellow tongue fur or yellow greasy；4, wiry and frequent pulse or sliding number.

Minor symptom: fever, pharyngalgia is thirsty, and uncomfortable in chest, general fatigue is hard and dry or half congealed and not well, scanty drak urine.

Primary symptom 1 is indispensable, and has 2 in 2,3,4 primary symptoms, or primary symptom 1 is indispensable, and has wantonly 1 and minor symptom in primary symptom 2,3,4 In wantonly 2 persons, that is, diagnosable.

3 are included in standard

Cough belongs to the hot patient of phlegm, and course of disease person within 1 week, the age is between 18~55 years old.

4 evaluation criteria

Recovery from illness: cough, expectoration, fever disappear, and other simultaneous phenomenons are clearly better.

Effective: cough, expectoration, fever are clearly better, and other simultaneous phenomenons are improved.

Effective: cough, expectoration, fever are improved, and other simultaneous phenomenon variations are little.

Invalid: clinical symptoms are without improvement or aggravate.

5 treatment methods

Give 5 oral liquid treatment of the embodiment of the present invention, 2 every time, every 10ml, 3 times a day.

6 results

By treatment in 5-7 days, clinical efficacy was shown in Table 1.

The clinical efficacy of 1 present invention treatment cough of table

	n	Recovery from illness	It is effective	Effectively	In vain	Cure rate (%)	Total effective rate (%)
								Curative effect	86	42	18	18	8	48.8	90.7

As shown in Table 1, after treatment in 5-7 days, the present invention is 48.8% to the cure rate of phlegm-heat cough, total effective rate It is 90.7%.As the result is shown: the traditional chinese medicine composition of the invention phlegm-heat cough has preferable therapeutic effect.

Typical case

Wei, female, medical Shi Jianqi expression is wan and sallow, lustreless complexion, receives that food is tasteless, tongue is yellow, wiry and frequent pulse, readme cough two Week half, sticky sputum.X-ray checks that increased bronchovascular shadows, the double pulmonary respiration sounds of physical examination are thick.It is diagnosed as phlegm-heat cough.Give the embodiment of the present invention The treatment of 4 capsules, cough symptom almost disappears after 5 days, and following the service 3 days, all cards removed to the greatest extent, and follow-up is without recurrence after 1 week.

Although above having used general explanation, specific embodiment and test, the present invention is made to retouch in detail It states, but on the basis of the present invention, it can be made some modifications or improvements, this is apparent to those skilled in the art 's.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to claimed Range.

Claims (7)

1. a kind of Chinese medicine composition for treating cough, it is characterised in that it is by including that the Chinese medicine material of following parts by weight is made :

2-30 parts of radix scutellariae, 2-30 parts of almond, 2-30 parts of campanulaceae, 2-30 parts of Chinese yam, 2-30 parts of perilla seed, 2-30 parts of terminalia flesh, Lay 2-30 parts of Fu, 10-50 parts of viola mandshurica, 1-15 parts of charred FRUCTUS CRATAEGI, 1-15 parts of malt, 1-15 parts of rice sprout, 1-15 parts of Divine Comedy.

2. the Chinese medicine composition for the treatment of cough as described in claim 1, it is characterised in that it is by including following parts by weight Made of Chinese medicine material:

4-20 parts of radix scutellariae, 4-20 parts of almond, 4-20 parts of campanulaceae, 4-20 parts of Chinese yam, 4-20 parts of perilla seed, 4-20 parts of terminalia flesh, Lay 4-20 parts of Fu, 15-40 parts of viola mandshurica；1-10 parts of charred FRUCTUS CRATAEGI, 1-10 parts of malt, 1-10 parts of rice sprout, 1-10 parts of Divine Comedy.

3. the Chinese medicine composition for the treatment of cough as claimed in claim 1 or 2, it is characterised in that its active constituent is using water It mentions or the extraction of the ethyl alcohol of 40-80% concentration expressed in percentage by volume is prepared.

4. the Chinese medicine composition for the treatment of cough as claimed in claim 3, it is characterised in that its active constituent is by following What method was prepared: taking 12 taste medicinal materials, extracting in water 2-3 times after mixing, each amount of water is equivalent to the 6- of medicinal material total weight 12 times, each extraction time is 1-3 hours, and combined extract, filtration, relative density is when filtrate is concentrated into 70-80 DEG C 1.15-1.20 clear cream to get active constituent.

5. the Chinese medicine composition for the treatment of cough as claimed in claim 3, it is characterised in that its active constituent is by following What method was prepared: taking 12 taste medicinal materials, extracted 2-3 times after mixing with 40-80% alcohol reflux, each ethanol consumption is medicinal material 4-10 times of total amount, extraction time are 1-4 hours, and combined extract, filtering, relative density is when filtrate is concentrated into 70-80 DEG C 1.15-1.20 clear cream to get active constituent.

6. the Chinese medicine composition for the treatment of cough as claimed in claim 3, it is characterised in that its active constituent is by following What method was prepared: taking 12 taste medicinal materials, extracting in water 2-3 times after mixing, each amount of water is equivalent to the 6- of medicinal material total weight 12 times, each extraction time is 1-3 hours, combined extract, filtration, and relative density is 1.15- when filtrate is concentrated into 70-80 DEG C Ethyl alcohol is added in 1.20 clear cream, makes alcohol content 40-70%, stands 12-24 hours, and filtration, filtrate is concentrated into 70-80 DEG C of phase To the medicinal extract that density is 1.10-1.25 to get active constituent.

7. a kind of Chinese medicine composition for treating cough, by the Chinese medicine composition and medicine for the treatment of cough of any of claims 1 or 2 Acceptable carrier combination is prepared on.