CN104547676B - It is a kind of to treat stationary phase bronchiectasic Chinese medicine composition and its preparation - Google Patents
It is a kind of to treat stationary phase bronchiectasic Chinese medicine composition and its preparation Download PDFInfo
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Abstract
The present invention is a kind of Chinese medicine composition to stationary phase bronchiectasis with significant curative effect.It is made of ginseng, Radix Astragali, Schisandra chinensis, the fruit of Chinese wolfberry, adenophora tetraphylla, Radix Glehniae, Radix Ophiopogonis, lily, Radix Rehmanniae, the root bark of white mulberry, the root bark of Chinese wolf-berry, Radix Salviae Miltiorrhizae, bulbus fritillariae cirrhosae, bamboo juice；Invention formulation includes：Capsule, granule, tablet, pill, oral liquid.The invention preparation, raw material are easy to get.Nourishing Yin and promoting production of body fluid of the present invention, moistens the lung and relieve the cough, invigorating the spleen expectoration dampness elimination, full side gather altogether invigorating qi for consolidating superficies, tonifying lung yin-nourishing, invigorating the spleen expectoration dampness elimination, anti-inflammatory relieving asthma, work(promoting blood circulation and removing blood stasis, hit the stationary phase bronchiectasis interpretation of the cause, onset and process of an illness.It is mainly used for stationary phase bronchiectasic treatment.
Description
Technical field
The present invention relates to treatment stationary phase bronchiectasic Chinese medicine composition and its preparations, belong to tcm field
Background technology
Bronchiectasis is the disease caused by the chronic abnormal dilatation of bronchus, belong to the respiratory disease that is difficult to effect a radical cure it
One.Due to bronchus and its surrounding tissue chronic inflammation and bronchial obstruction, the pathology for causing bronchial tissue's structure more serious
Property destroy so that bronchus lumen distention and deformation.Main clinical manifestation is chronic cough, vomicas and spit blood repeatedly.Easily simultaneously
Send out pulmonary abscess, pulmonary emphysema, pulmonary heart disease.This disease is very common in China rural area, and disability rate and lethality are high.Therefore it needs to have taken
The control measure of effect is intervened.Clinic groundwork at present focuses on treatment bronchiectasis acute exacerbation, and for steady
How regular patient alleviates clinical symptoms, reduces acute exacerbation, delays disease progression, improves health status, improves existence matter
Amount, means are very limited.Include smoking cessation, preventing cold, the inoculation of multivalence pneumovax at present and relievingd asthma using Western medicine drug, eliminating the phlegm
Remedy measures all obtain certain effect, but the disease does not obtain Satisfactory Control yet, it is especially bronchiectasic in stationary phase
Treatment.How to avoid acute exacerbation is vital in the prevention of the disease.The advantage of the traditional Chinese medical science is played, it can be to stationary phase branch
Tracheaectasy carries out therapeutic intervention, reduces acute exacerbation, improves clinical symptoms.But it is curative for effect, it can effectively treat stationary phase
Bronchiectasic Chinese medicine preparation still lacks very much, and the present invention is to be developed, processed according to local traditional proved recipe, developed and obtain
, raw material is easy to get, and drug is in itself without toxic side effect, and relatively more safe and reliable, drug is with obvious effects, while its production method
Simple and practicable, Conventional processing methods are used in the production of bulk pharmaceutical chemicals provided by the invention, will not lead to the loss of active ingredient.
Invention content
The purpose of the present invention is to provide a kind of therapeutic effect it is good, have no toxic side effect, treatment curative for effect treatment stablize
Phase bronchiectasic Chinese medicine composition and its preparation, with overcome the deficiencies in the prior art.
The technical solution that the present invention solves above-mentioned technical problem is as follows：
It is a kind of to treat stationary phase bronchiectasic Chinese medicine composition, include the raw material of following parts by weight：
By 3-6 parts of ginseng, 10-20 parts of Radix Astragali, 10-20 parts of Schisandra chinensis, 10-20 parts of the fruit of Chinese wolfberry, 10-20 parts of adenophora tetraphylla, north
10-20 parts of the root of straight ladybell, Radix Ophiopogonis 10-20 part, 10-20 parts of lily, 10-20 parts of Radix Rehmanniae, 10-20 parts of the root bark of white mulberry, 10-20 parts of the root bark of Chinese wolf-berry,
10-20 parts of 10-20 parts of Radix Salviae Miltiorrhizae, 10-20 parts of bulbus fritillariae cirrhosae, bamboo juice compositions.
As the further preferred of above-mentioned technical proposal, the composite preparation includes the raw material of following parts by weight：
3 parts of ginseng, 10 parts of Radix Astragali, 10 parts of Schisandra chinensis, 10 parts of the fruit of Chinese wolfberry, 10 parts of adenophora tetraphylla, 10 parts of Radix Glehniae, Radix Ophiopogonis 10
20 parts of part, 10 parts of lily, 10 parts of Radix Rehmanniae, 10 parts of the root bark of white mulberry, 10 parts of the root bark of Chinese wolf-berry, 10 parts of Radix Salviae Miltiorrhizae, 10 parts of bulbus fritillariae cirrhosae, bamboo juice compositions.
Preparation of the present invention is presses any manufactured dosage form of the prior art in Chinese medicine production, including capsule preparations, particle
Electuary, tablet, pill or oral liquid formulations.
In the above-mentioned technical solutions, each taste Chinese medicine in compositing formula has effects that as follows：
The invention is mainly made of 14 kinds of Chinese medicines, wherein ginseng, Radix Astragali, fill temperature sun, invigorating qi for consolidating superficies；Schisandra chinensis, matrimony vine
Son, nourishing Yin and promoting production of body fluid of astringing the lung；Adenophora tetraphylla, Radix Glehniae, Radix Ophiopogonis, lily, Radix Rehmanniae, Yin nourishing and lung moistening；The root bark of white mulberry, the root bark of Chinese wolf-berry, Radix Salviae Miltiorrhizae, eliminating the phlegm
It is active；Bulbus fritillariae cirrhosae, bamboo juice, clearing lung-heat heat, eliminating the phlegm.The invention nourishing Yin and promoting production of body fluid, moistens the lung and relieve the cough, invigorating the spleen expectoration dampness elimination, complete square benefit of gathering altogether
Superficies-consolidating, tonifying lung yin-nourishing, invigorating the spleen expectoration dampness elimination, anti-inflammatory are relievingd asthma, work(promoting blood circulation and removing blood stasis, and hit the stationary phase bronchiectasis interpretation of the cause, onset and process of an illness.
The present invention is obtained from being developed, processed according to local traditional proved recipe, develop, and drug is in itself without the secondary work of poison
With relatively more safe and reliable, drug is with obvious effects, while its production method is simple and practicable, and Conventional processing methods carry for the present invention
In the production of the bulk pharmaceutical chemicals of confession, the loss of active ingredient will not be caused；And in the invention preparation, raw material is easy to get.
Traditional medicine thinks that this disease belongs to the scopes such as " spitting of blood ", " lung carbuncle ", " cough " of traditional Chinese medicine.This disease interpretation of the cause, onset and process of an illness is recognized at present
Know and be intended to asthenia in origin and asthenia in superficiality more.How empty prolonged illness is, and immunity of organisms is low and bronchial obstruction is the important original of repeated infection repeatedly
Cause.So should pay attention to strengthening the body resistance to consolidate the constitution in stationary phase, by help lung spleen kidney, to improve body's immunity, exopathogen is resisted in enhancing
Ability reduces the chance of recurrent exerbation.Lung, spleen, kidney deficiency damage, retention of phlegm and blood stasis in the lung, strongly fragrant longization heat, heat stop up blood stasis, pathogens accumulating to form abscess, for this
The inherent interpretation of the cause, onset and process of an illness pathological change of disease, pathogenic characteristic are asthenia in origin and asthenia in superficiality, and for this void based on lung spleen kidney deficiency, mark is real with lung heat, phlegm wet, blood
Based on the stasis of blood, phlegm, the stasis of blood, hot three be the touching delay of this disease, recurrent exerbation basic reason.The disease stationary phase is more based on this void
It is lung spleen kidney deficiency damage, belongs to lung Pishenqixu syndrome, and have the lung-dryness syndrome due to yin deficiency.It is preferably consolidated with QI invigorating, yin-nourishing invigorating the spleen, promoting blood circulation and removing blood stasis, anti-inflammatory
The method of expectoration, so that inside of human body negative and positive of qi and blood balances, viscera function is restored, and immune function improves, so as to reduce breaking-out time
Number improves Nutritional Status of Patients and quality of life.This is the dialectical basis of the present invention.The present invention is also that the traditional Chinese medical science is " slow then control it
This ", " prevention of diseae ", " i.e. disease is preapred for an unfavorable turn of events " principle fully demonstrate.
By adopting the above-described technical solution, the present invention is consolidated with QI invigorating, yin-nourishing invigorating the spleen is promoting blood circulation and removing blood stasis, anti-inflammatory expectoration
Effect.Inventor started before the several years using technical solutions according to the invention, and treatment hundreds stationary phase bronchiectasis is suffered from
Person obtains the effect of fine.
Specific embodiment：
The first：Take ginseng 3g, Radix Astragali 10g, Schisandra chinensis 10g, fruit of Chinese wolfberry 10g, adenophora tetraphylla 10g, Radix Glehniae 10g, Radix Ophiopogonis
10g, lily 10g, Radix Rehmanniae 10g, root bark of white mulberry 10g, root bark of Chinese wolf-berry 10g, Radix Salviae Miltiorrhizae 10g, bulbus fritillariae cirrhosae 10g, bamboo juice 20g, by above-mentioned raw materials
Medicine is fried into decoction and takes, one dose per day, is divided into and taking twice sooner or later, even served 30 days.
Second：By weight：Ginseng 3, Radix Astragali 10, Schisandra chinensis 10, the fruit of Chinese wolfberry 10, adenophora tetraphylla 10, Radix Glehniae 10, Radix Ophiopogonis
10th, lily 10, Radix Rehmanniae 10, the root bark of white mulberry 10, the root bark of Chinese wolf-berry 10, Radix Salviae Miltiorrhizae 10, bulbus fritillariae cirrhosae 10, bamboo juice 20, by above-mentioned raw materials medicine with kilogram
For the fried concentration of unit of weight, honey is smelt ball.0.5 gram is weighed per ball, 6 balls is respectively taken sooner or later, continuously takes 30 days.
The third：By weight：Ginseng 3, Radix Astragali 10, Schisandra chinensis 10, the fruit of Chinese wolfberry 10, adenophora tetraphylla 10, Radix Glehniae 10, Radix Ophiopogonis
10th, lily 10, Radix Rehmanniae 10, the root bark of white mulberry 10, the root bark of Chinese wolf-berry 10, Radix Salviae Miltiorrhizae 10, bulbus fritillariae cirrhosae 10, bamboo juice 20, by above-mentioned raw materials medicine with kilogram
It is processed into fine powder jointly for unit of weight, crosses more than 100 mesh and sieves, is uniformly mixed, ozone sterilization 20 minutes, routinely technique is made
Capsule, every 0.5 gram of weight respectively take 4-6 sooner or later, and warm water delivery service continuously takes 30 days.
4th kind：By weight ginseng 3, Radix Astragali 10, Schisandra chinensis 10, the fruit of Chinese wolfberry 10, adenophora tetraphylla 10, Radix Glehniae 10, Radix Ophiopogonis
10th, lily 10, Radix Rehmanniae 10, the root bark of white mulberry 10, the root bark of Chinese wolf-berry 10, Radix Salviae Miltiorrhizae 10, bulbus fritillariae cirrhosae 10, bamboo juice 20, above-mentioned raw materials medicine is added in
Liquid after being sufficiently mixed into liquid, is decocted into cream, is condensed into particle by 500ml water, pack, and every bag of 3 grams of weight respectively takes 1 sooner or later
Bag, warm water delivery service continuously take 30 days.
5th kind：By weight：Ginseng 3, Radix Astragali 10, Schisandra chinensis 10, the fruit of Chinese wolfberry 10, adenophora tetraphylla 10, Radix Glehniae 10, Radix Ophiopogonis
10th, lily 10, Radix Rehmanniae 10, the root bark of white mulberry 10, the root bark of Chinese wolf-berry 10, Radix Salviae Miltiorrhizae 10, bulbus fritillariae cirrhosae 10, bamboo juice 20, above-mentioned raw materials medicine is added in
1000ml water, after being sufficiently mixed into liquid, then routinely oral liquid manufacture craft, liquid is decocted and is concentrated into 200ml, you can system
The present invention oral liquid formulations.The instructions of taking of oral liquid：Twice daily, each 10-20ml, warm water delivery service are continuous to take
30 days.
6th kind：By weight：Ginseng 3, Radix Astragali 10, Schisandra chinensis 10, the fruit of Chinese wolfberry 10, adenophora tetraphylla 10, Radix Glehniae 10, Radix Ophiopogonis
10th, lily 10, Radix Rehmanniae 10, the root bark of white mulberry 10, the root bark of Chinese wolf-berry 10, Radix Salviae Miltiorrhizae 10, bulbus fritillariae cirrhosae 10, bamboo juice 20, by above-mentioned raw materials medicine with kilogram
It is processed into fine powder, then routinely tablet manufacture craft jointly for unit of weight, medicinal powder is pressed into 0.3 gram every of tablet, you can
The tablet of the present invention of system.The instructions of taking of tablet：Twice daily, each 3-4 pieces, warm water delivery service continuously take 30 days.
Clinical practice：
1 clinical data
Bronchiectasis diagnosis according to《Clinical practice》7th edition, stationary phase bronchiectasis patient 72 is selected, it is random to divide
It it is 2 groups, invention group group (treatment group) organizes 36, and male 23, women 13 is 47~71 years old age, 57.4 years old average, average disease
Journey 8.7 years；Simple western medical treatment group (control group) 36, male 22, women 14；It is 45~68 years old age, 56.2 years old average；
Average course of disease 9.1 years；Above-mentioned case reached stationary phase to 2 months 20143 from October, 2013 after my section's hospitalization
The patient of discharge completes treatment observation, and informed consent.
2 therapies
Control group gives western medicine routine treatment such as：Posture drainage uses expectorant, bronchodilator, lung reconditioning
Deng treatment.The same control group of the above-mentioned western medicine routine treatment for the treatment of group, separately gives the decoction of present invention side, by system system of boiling medicine during clinical application
One is fried, and every dose of medicine decocts into 200mL, is divided to two bags of packagings, respectively takes 1 bag sooner or later, 30d is 1 course for the treatment of, and effect is observed after continuous 3 courses for the treatment of
Fruit.
3 curative effect judging standards
It is effective：Cough, expectoration, hemoptysis, it is uncomfortable in chest, feel suffocated, the symptoms such as cyanosis disappear substantially, two lung dry and wet rales significantly subtract
Gently；Effectively：Above-mentioned symptom is improved in varying degrees；In vain：Without improvement or deteriorate with symptom before treatment.
4 results
Effect is as follows after two groups of patients, 3 courses for the treatment of：
Two groups of pretherapy and post-treatment effects compare (x ± s)
Note：The P ＜ 0.05 compared with after control group treatment.
In short, treating stationary phase bronchiectasis with the invention, curative for effect directly against the interpretation of the cause, onset and process of an illness of this disease, poison is secondary
It acts on small, is the effective ways being worthy to be popularized.
Claims (3)
1. a kind of treat stationary phase bronchiectasic Chinese medicine composition, it is characterized in that：According to weight proportion：It is by people
Ginseng 3-6 parts, 10-20 parts of Radix Astragali, 10-20 parts of Schisandra chinensis, 10-20 parts of the fruit of Chinese wolfberry, 10-20 parts of adenophora tetraphylla, 10-20 parts of Radix Glehniae,
Radix Ophiopogonis 10-20 part, 10-20 parts of lily, 10-20 parts of Radix Rehmanniae, 10-20 parts of the root bark of white mulberry, 10-20 parts of the root bark of Chinese wolf-berry, 10-20 parts of Radix Salviae Miltiorrhizae,
10-20 parts of bulbus fritillariae cirrhosae, 10-20 parts of bamboo juice are made.
2. treatment stationary phase bronchiectasic Chinese medicine composition as described in claim 1, it is characterized in that：Required bulk pharmaceutical chemicals
Optimum ratio be 3 parts of ginseng, 10 parts of Radix Astragali, 10 parts of Schisandra chinensis, 10 parts of the fruit of Chinese wolfberry, 10 parts of adenophora tetraphylla, 10 parts of Radix Glehniae, Radix Ophiopogonis
10 parts, 10 parts of lily, 10 parts of Radix Rehmanniae, 10 parts of the root bark of white mulberry, 10 parts of the root bark of Chinese wolf-berry, 10 parts of Radix Salviae Miltiorrhizae, 10 parts of bulbus fritillariae cirrhosae, 20 parts of bamboo juice system
Into.
3. treatment stationary phase bronchiectasic Chinese medicine composition as claimed in claim 1 or 2, it is characterized in that：In described
The preparation of drug composition is obtainable preparation in the production of all Chinese medicines.
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| CN105012766A (en) * | 2015-08-20 | 2015-11-04 | 济南邦文医药科技有限公司 | Traditional Chinese medicine for treating bronchiectasis in stable period |
| CN104998066A (en) * | 2015-08-20 | 2015-10-28 | 济南邦文医药科技有限公司 | Traditional Chinese medicine for treating bronchiectasia in acute infection period |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1253810A (en) * | 1999-10-18 | 2000-05-24 | 厉福昌 | Medicine for curing chronic bronchitis and its preparation method |
| CN1569102A (en) * | 2004-04-27 | 2005-01-26 | 孟庆云 | Medicine for treating bronchodilatation |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1253810A (en) * | 1999-10-18 | 2000-05-24 | 厉福昌 | Medicine for curing chronic bronchitis and its preparation method |
| CN1569102A (en) * | 2004-04-27 | 2005-01-26 | 孟庆云 | Medicine for treating bronchodilatation |
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| CB03 | Change of inventor or designer information |
Inventor after: Xu Mei Inventor before: Zou Deqi Inventor before: Liu Huantao Inventor before: Bi Xiumei Inventor before: Sui Yueling Inventor before: Sun Weihua |
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Effective date of registration: 20180517 Address after: 266701 Li Yuan Street office health center, 383 Renmin Road, Pingdu City, Qingdao, Shandong Applicant after: Xu Mei Address before: 265100 Haiyang City Third People's Hospital, 3 Haihua Road, Haiyang, Yantai, Shandong Applicant before: Zou Deqi |
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