CN106421304A - Traditional Chinese medicine for treating exogenous cough during pregnancy - Google Patents

Traditional Chinese medicine for treating exogenous cough during pregnancy Download PDF

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Publication number
CN106421304A
CN106421304A CN201610968316.9A CN201610968316A CN106421304A CN 106421304 A CN106421304 A CN 106421304A CN 201610968316 A CN201610968316 A CN 201610968316A CN 106421304 A CN106421304 A CN 106421304A
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chinese medicine
traditional chinese
cough
medicine composition
herb
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王莹莹
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285Aucklandia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/76Salicaceae (Willow family), e.g. poplar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to the field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for treating an exogenous cough during pregnancy. According to etiology and pathogenesis of the exogenous cough during pregnancy, the active pharmaceutical ingredients such as ternate-leaved rabdosia, herb of laminated sanicle, stems and leaves of slender-spike gouania, radix clematidis, white poplar leaves, fibrous roots of fistular onions, foetid gymnema and myriopteron extensum are carefully selected. The traditional Chinese medicine composition has the effects of expelling wind, removing cold, moistening the lung for removing phlegm, relieving cough and asthma, tonifying qi and preventing miscarriage, by means of clinical verification, the total effective rate is 96.67%, and the traditional Chinese medicine composition is worthy of clinical popularization.

Description

A kind of Chinese medicine composition treating exogenous pregnant cough
Technical field
The invention belongs to the field of Chinese medicines is and in particular to a kind of Chinese medicine composition treating exogenous pregnant cough.
Background technology
Gestation, cough or chronic cough endlessly, referred to as " pregnant cough ".Pregnant woman illness after, often occur the soreness of waist, stomachache, The symptoms such as underbelly falling inflation, if chronic cough is not healed, the easy tired mind of pregnant woman, body is become thin, hectic fever night sweat, blood-stained sputum, severe patient Easily hinder tire, lead to nausea impaired.
Doctor trained in Western medicine thinks that pregnant cough is that the gestation merging infection of the upper respiratory tract, acute/chronic bronchitis, pneumonia etc. cause. The traditional Chinese medical science thinks, the generation of pregnant cough is relevant with gestational period special physiological with development, and main pathogenesis are that lung mistake makes moist, respectful clearly Dereliction of duty.Deficiency of Yin card type, phlegm and retained fluid card type and diseases caused by external factors card type clinically can be divided into.What the present invention mainly studied is clinically relatively common Exogenous pregnant cough.The main clinical manifestation of exogenous pregnant cough is:Gestation, cough phlegm is dilute, runny nose of having a stuffy nose, head Bitterly detest cold, joint is miserable, tongue is thin white, floating-rolling pulse.
At present, this disease of western medical treatment there is no effect is significant and the specific drug having no side effect, how using hormone medicine treatment, And cure the symptoms, not the disease, individual drugs have side effect to fetus.Due to being pregnant in body, patient worries some toxicities of Western medicine, Mostly it is reluctant to accept western medicine, and seek medical advice in traditional Chinese medicine.This sick extensive patients need badly one kind can treat both principal and secondary aspect of disease, no according to Lazyness, pregnant woman and fetal well-being are effectively treated with the Chinese medicine of exogenous pregnant cough.
Content of the invention
It is an object of the invention to carrying a kind of Chinese medicine composition treating exogenous pregnant cough, have treat both principal and secondary aspect of disease, The features such as take effect rapid, effective to pregnant woman and fetal well-being.
Technical program of the present invention lies in:A kind of Chinese medicine composition treating exogenous pregnant cough is joined by following weight parts The bulk drug composition of ratio:Ternateleaf rabdosia herb 25-50, laminated sanicle herb 6-15, blowing rattan 10-15, smelly Wheeling 15-25, white aspen leaf 10-15, Green onion must 10-15, jump eight zhang of 15-25, root of Extensed Wingfruitvine 25-50.
Preferably, a kind of bulk drug group by following weight parts proportioning for the Chinese medicine composition treating exogenous pregnant cough Become:Ternateleaf rabdosia herb 40, laminated sanicle herb 6, blowing rattan 15, smelly Wheeling 20, white aspen leaf 15, green onion palpus 15, jump eight zhang 20, root of Extensed Wingfruitvine 30.
Contained by the present invention, the pharmacological property of each bulk drug is analyzed as follows.
Ternateleaf rabdosia herb:Herb for dicotyledon medicine labiate glaucocalyx rabdosia herb.Nature and flavor:Pungent slight bitter, temperature.Return lung, Liver two warp.Can expelling wind and clearing away cold, resolving sputum reason wet.Cure cold, cough, jaundice, rheumatism swells and ache, dentalgia, knife wound bleeding.《Guangxi medicine is planted Register》:Preventing phlegm from forming and stopping coughing, consumer edema.Control typhoid fever, jaundice, cough, the arthroncus of knee, infantile malnutrition, rheumatism.
Laminated sanicle herb:Herb for samphire thin slice sanicle and sky blue sanicle.There is wind-dispelling deliver, resolving sputum stops Cough, the effect of promoting blood circulation for regulating menstruation.It is usually used in catching a cold, cough, asthma, irregular menstruation, Amenorrhea, dysmenorrhoea, sore swells, treating swelling and pain by traumatic injury, wound Bleeding.
Blowing rattan:Root for Icacinaceae plant lodes vitiginea and stem rattan.Nature and flavor:Pungent;Tepor.Can expelling wind and clearing away cold;Remove Wet dredging collateral.Cure mainly wind-cold-dampness arthralgia;Ephritis;Internal lesion caused by overexertion.
Smelly Wheeling:Root for composite family Genus Saussurea plant cotton wool hieracioides is used as medicine.Nature and flavor:Sweet, acrid, warm.Can moisten the lung and relieve the cough, Removing toxic substances pain relieving.For pulmonary tuberculosis, bronchitis, spitting of blood, antimigraine.
White aspen leaf:Leaf for Salicaceous Plants white poplar.Can eliminating the phlegm, anti-inflammatory, relieving asthma, cough-relieving.Control chronic bronchitis, cough Cough, pant.
Green onion palpus:Fibrous root for liliaceous plant green onion.Cure mainly anemofrigid headache, larynx sore, frostbite.
Jump eight zhang:Root for trailing plants section Gymnema plant Gymnema foetidum Tsiang is used as medicine.Nature and flavor:Pungent, puckery, tepor.Can relax the muscles and stimulate the blood circulation, Antiabortive pain relieving.For traumatic injury, treating rheumatic ostealgia, pain in the back, fetal irritability, ephritis, amenorrhoea, dysmenorrhoea.
Root of Extensed Wingfruitvine:Root for trailing plants section root of Extensed Wingfruitvine is used as medicine.Nature and flavor:Sweet, bitter, pungent.Can tonifying middle-Jiao and Qi, cough-relieving, menstruation regulating.Cure mainly Flu, cough, menorrhalgia, the prolapse of uterus, prolapse of the anus.
Chinese medicine composition of the present invention is decoction.Its preparation method is:Add water appropriate, by traditional Chinese medicine decocting method decocting two Secondary, merging filtrate obtains final product.During medication, avoid clothes sugar.
It has been recognised by the inventors that the principal pathogenetic reason of exogenous pregnant cough is:Chill violate lung, strongly fragrant hold back air flue, lung qi can not A surname freely then coughs, runny nose of having a stuffy nose;In flesh table, cold tending to coagulate and stagnate is inaccessible for chill bundle, and sun is strongly fragrant not to be reached, therefore headache aversion to cold, and joint is miserable.Tongue Bao Bai, floating-rolling pulse, is chill levying in table.
The present invention according to this sick etiology and pathogenesis, with ternateleaf rabdosia herb, blowing rattan, laminated sanicle herb expelling wind and clearing away cold, dispelling phlegm and eliminating dampness, dissipates cold Dredging collateral, with smelly Wheeling, white aspen leaf moistening lung for removing phlegm, relieving cough and asthma, must control anemofrigid headache with green onion, with jumping eight zhang of antiabortive pain relievings, use wing Fruit rattan tonifying middle-Jiao and Qi.Side has functions that expelling wind and clearing away cold, moistening lung for removing phlegm, relieving cough and asthma, tonifying Qi are antiabortive entirely.
Specific embodiment
Embodiment 1:A kind of Chinese medicine composition treating exogenous pregnant cough(Unit:Gram):Ternateleaf rabdosia herb 25, laminated sanicle herb 6th, blowing rattan 10, smelly Wheeling 15, white aspen leaf 10, green onion palpus 10, jump eight zhang 15, root of Extensed Wingfruitvine 25.Add water appropriate, decoct by traditional Chinese medicine Twice, merging filtrate obtains final product method decocting.During medication, avoid clothes sugar.
Embodiment 2:A kind of Chinese medicine composition treating exogenous pregnant cough(Unit:Gram):Ternateleaf rabdosia herb 40, laminated sanicle herb 6th, blowing rattan 15, smelly Wheeling 20, white aspen leaf 15, green onion palpus 15, jump eight zhang 20, root of Extensed Wingfruitvine 30.Add water appropriate, decoct by traditional Chinese medicine Twice, merging filtrate obtains final product method decocting.During medication, avoid clothes sugar.
Embodiment 3:A kind of Chinese medicine composition treating exogenous pregnant cough(Unit:Gram):Ternateleaf rabdosia herb 50, laminated sanicle herb 15th, blowing rattan 15, smelly Wheeling 25, white aspen leaf 15, green onion palpus 15, jump eight zhang 25, root of Extensed Wingfruitvine 50.Add water appropriate, decoct by traditional Chinese medicine Twice, merging filtrate obtains final product the method decocting of boiling.During medication, avoid clothes sugar.
Below, in conjunction with clinical data, beneficial effects of the present invention are described further.
1 data and method
1.1 physical data
In May, 2014 first arrival in May, 2016 is selected to suffer from 120 exogenous gestational period coughs of certain Grade A hospital outpatient clinic Person, the age, at 4 weeks to 35 weeks, the course of disease was at 3 15 days for pregnant week at 23 41 years old.The pregnant front all no chronic cough medical histories of patient, Clinical health check-up prompting intrauterine fetal is developed normally, and pregnant woman's language is deep or hoarse, and pharyngeal cavity is slightly congested, and the double pulmonary respiration sound of auscultation is clear Clear or slightly coarse, but do not hear and significantly wet sound.It is randomly divided into treatment group 60, control group 60.
120 patients all meet the Symptoms of exogenous pregnant cough, and clinical symptoms are how dilute with phlegm of coughing, nasal obstruction stream Tears, aversion to cold of having a headache, joint is miserable, and tongue is thin white, floating-rolling pulse.
1.2 treatment method
Treatment group:Take the Chinese medicine composition that the present invention treats exogenous pregnant cough(Unit:Gram):Ternateleaf rabdosia herb 40, big lung muscle Grass 6, blowing rattan 15, smelly Wheeling 20, white aspen leaf 15, green onion palpus 15, jump eight zhang 20, root of Extensed Wingfruitvine 30.Add water appropriate, decoct by traditional Chinese medicine Twice, merging filtrate obtains final product the method decocting of boiling.When taking, daily 1 dose, decocting takes 400ml, and a point morning and evening warmly takes, and during medication, avoids Clothes sugar.It serve on five days and observe curative effect.
Control group:Take cough due to wind-cold evil's particle(Chinese medicines quasi-word Z53020984, Yunnan Ming Ding pharmaceutcal corporation, Ltd produces, 5g*10 bag/box)Boiling water is taken after mixing it with water, a 5g, 2 times a day.It serve on five days and observe curative effect.
2 results
2.1 efficacy determination
Cure:The clinical symptom disappearance such as cough;
Take a turn for the better:The clinical symptoms such as cough are obviously improved;
Invalid:The clinical symptoms such as cough no mitigate or increase.
2.2 treatment results
Cure Take a turn for the better Invalid Total effective rate
Treatment group 36(60.00%) 22(36.67%) 2(3.33%) 96.67%
Control group 21(35.00%) 25(41.67%) 14(23.33%) 76.67%
Contrast finds, the treatment group's total effective rate taking Chinese medicine composition of the present invention is 96.67%, is significantly higher than and takes chill and cough Cough the control group of particle.During medication, do not find the bad reactions such as heating, fetal irritability.

Claims (2)

1. a kind of Chinese medicine composition treating exogenous pregnant cough is it is characterised in that bulk drug by following weight parts proportioning Composition:Ternateleaf rabdosia herb 25-50, laminated sanicle herb 6-15, blowing rattan 10-15, smelly Wheeling 15-25, white aspen leaf 10-15, green onion must 10-15, Jump eight zhang of 15-25, root of Extensed Wingfruitvine 25-50.
2. as claimed in claim 1 a kind of Chinese medicine composition treating exogenous pregnant cough it is characterised in that by following heavy The bulk drug composition of amount part proportioning:Ternateleaf rabdosia herb 40, laminated sanicle herb 6, blowing rattan 15, smelly Wheeling 20, white aspen leaf 15, green onion palpus 15, jump Eight zhang 20, root of Extensed Wingfruitvine 30.
CN201610968316.9A 2016-11-06 2016-11-06 Traditional Chinese medicine for treating exogenous cough during pregnancy Pending CN106421304A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103877547A (en) * 2014-03-22 2014-06-25 苑丕吉 Traditional Chinese medicine for treating cough in pregnancy
CN105250839A (en) * 2015-10-14 2016-01-20 孙小珂 Traditional Chinese medicine composition for treating coughs during pregnancy

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103877547A (en) * 2014-03-22 2014-06-25 苑丕吉 Traditional Chinese medicine for treating cough in pregnancy
CN105250839A (en) * 2015-10-14 2016-01-20 孙小珂 Traditional Chinese medicine composition for treating coughs during pregnancy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
蔡莉菁,姚美玉, 王欣欣, 吉海荣: "桑菊饮加味治疗外感妊娠期咳嗽", 《黑龙江医药》 *

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Application publication date: 20170222