CN108837090A - A kind of Chinese medicine composition and preparation method for Intensive Care Therapy infection in respiratory system - Google Patents

A kind of Chinese medicine composition and preparation method for Intensive Care Therapy infection in respiratory system Download PDF

Info

Publication number
CN108837090A
CN108837090A CN201811020489.3A CN201811020489A CN108837090A CN 108837090 A CN108837090 A CN 108837090A CN 201811020489 A CN201811020489 A CN 201811020489A CN 108837090 A CN108837090 A CN 108837090A
Authority
CN
China
Prior art keywords
parts
chinese medicine
radix
respiratory system
intensive care
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811020489.3A
Other languages
Chinese (zh)
Inventor
刘征远
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Ruihua Department Of Orthopedics Hospital Co Ltd
Original Assignee
Suzhou Ruihua Department Of Orthopedics Hospital Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Ruihua Department Of Orthopedics Hospital Co Ltd filed Critical Suzhou Ruihua Department Of Orthopedics Hospital Co Ltd
Priority to CN201811020489.3A priority Critical patent/CN108837090A/en
Publication of CN108837090A publication Critical patent/CN108837090A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a kind of Chinese medicine composition and preparation method for Intensive Care Therapy infection in respiratory system, which is made of the raw material components of following parts by weight:15-28 parts of asarum, Radix Ophiopogonis 13-21 part, 8-19 parts of reed root, 7-15 parts of gypsum, 15-23 parts of perilla leaf, 11-20 parts of Lasiosphaera fenzlii, 9-20 parts of indigo naturalis, 12-22 parts of Radix Isatidis, 11-21 parts of the root bark of Chinese wolf-berry, 7-11 parts of Radix Glycyrrhizae, 5-9 parts of honey.The present invention utilizes drug matching principle, and a variety of medicinal materials are used cooperatively, and has developed a kind of Chinese medicine preparation that can treat Intensive Care Therapy infection in respiratory system, drug effective percentage is up to 98.7%, and quick, pharmacological property mitigates, and toxic side effect is small, no dependence is conducive to patient and mitigates symptom in time.

Description

A kind of Chinese medicine composition and preparation method for Intensive Care Therapy infection in respiratory system
Technical field
The invention belongs to pharmaceutical technology field, be related to a kind of Chinese medicine composition for Intensive Care Therapy infection in respiratory system and Preparation method.
Background technique
Respiratory system is the general name for executing body and the extraneous organ for carrying out gas exchanges.The function of respiratory system is mainly Gas exchanges are carried out with the external world, are given off carbon dioxide, inspiration oxygen carries out metabolism.Respiratory system includes respiratory tract (nose Chamber, pharynx, larynx, trachea-bronchial epithelial cell) and lung.
Respiratory disease is a kind of common disease, frequently-occurring disease, and major lesions are in trachea-bronchial epithelial cell, lung and thoracic cavity, lesion Less serious case's mostly cough, pectoralgia, breathing is impacted, severe one has difficulty in breathing, anoxic or even respiratory failure and it is lethal.Death in city Rate accounts for the 3rd, and in rural area then account for the first.Infection in respiratory system is maximum, most common class in respiratory disease, past Toward with fever, inflammation, the pain of cough and respiratory system.
Doctor trained in Western medicine mostly uses antibiotic, antiviral and hormonotherapy at present, and therapeutic effect is barely satisfactory, and side effect is big, Easily cause the abuse of antibiotic.Chinese medicine thinks, the scopes such as " cough " of infection in respiratory system category traditional Chinese medicine, " phlegm retention ", " cough and asthma ". Think exopathogen invasion and lung, spleen, the dirty malfunction of kidney three, is the main reason for causing this disease.Human righteousness is insufficient, defends outer mistake Duty, being invaded by exogenous pathogen,invasion of exogenous pathogen, exopathogen either chill heresy, can also be the heresy of wind-heat, can also chill heresyization heat, invade lungs, make It is respectful that lung loses a surname;Or insufficiency of lung-QI, weakened defensive QI feel exopathogen again;Or weak with age, spleen-lung Qi deficiency, the dysfunction of the spleen in transport, it is wet to be polymerized to Phlegm stops storing in lung;Or lung has chronic ill, feels exopathogen again;Or after prolonged illness, kidney is undermined by spleen and lung, leads to deficiency of kidney-QI, gas of receiving is had no right Deng.Mainly there is following parting:1, chill beam table.Card is shown in:Aversion to wind and cold is heavier, and with fever, lossless or hypohidrosis is had a stuffy nose, stream Clear nasal discharge is sneezed, headache, limb aching pain, and not thirsty or cough spits dilute white phlegm, hoarseness, thin white fur of tongue and moisten, floating and tense pulse.It controls Then:Relieving the exterior syndrome with drugs pungent in flavor and warm in property, fever chill.2, wind-heat violates table.Card is shown in:Fever is obvious, micro- aversion to wind and cold, hypohidrosis, distending pain in the head, nasal obstruction, or stream Yellow tears, it is thirsty, red and pain is swallowed, yellow phlegm or white viscous phlegm are spat in cough, and tongue side point is red, and tongue fur is thin white and dry or micro- Huang, superficial and rapid pulse.The rules for the treatment of: Relieving the exterior syndrome with drugs pungent in flavor and cool in property, evacuation fever.3, summer-heat and damp attacks table.Card is shown in:Disease hair rises in summer symptoms include fever with aversion to cold, lossless or hypohidrosis, giddy Bitterly, nasal congestion, uncomfortable in chest, evil of vomitting is intended to spit, and tire is white greasy or yellow greasy, soft and moderate pulse or moistens number.The rules for the treatment of:Driving away summer heat inducing diaphoresis, dampness elimination is in.4, Heat attacks table.Card is shown in:Disease is mainly in autumn, symptoms include fever, slight chill, headache, hypohidrosis, and few phlegm of coughing, thirsty, dry throat lip is dry, skin Skin is dry, and tongue side point is red, and tongue fur is thin white and dry, floating pulse.The rules for the treatment of:Relieving the exterior syndrome with drugs pungent in flavor and cool in property, sweet tremble with fear are moisturized.
The present invention selects plurality of Chinese to carry out compatibility, this fundamentally treats Intensive Care Therapy infectious disease of respiratory system, reaches Treating both manifestation and root cause of disease.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition and preparation method for Intensive Care Therapy infection in respiratory system, Preparation gained Chinese medicine has that good curative effect, quick, medication time is short, treatment is complete for treatment Intensive Care Therapy infection in respiratory system Face, toxic side effect are small, drug goes directly lesion, treating both manifestation and root cause of disease.
The technical scheme adopted by the invention is that a kind of Chinese medicine composition for Intensive Care Therapy infection in respiratory system, by The raw material components of following parts by weight are made:15-28 parts of asarum, Radix Ophiopogonis 13-21 part, 8-19 parts of reed root, 7-15 parts of gypsum, perilla leaf 15-23 parts, 11-20 parts of Lasiosphaera fenzlii, 9-20 parts of indigo naturalis, 12-22 parts of Radix Isatidis, 11-21 parts of the root bark of Chinese wolf-berry, 7-11 parts of Radix Glycyrrhizae, honey 5-9 Part.
Further, a kind of Chinese medicine composition for Intensive Care Therapy infection in respiratory system, by the raw material of following parts by weight Component is made:20-25 parts of asarum, Radix Ophiopogonis 15-19 part, 12-16 parts of reed root, 12-15 parts of gypsum, 18-21 parts of perilla leaf, Lasiosphaera fenzlii 15-20 parts, 13-17 parts of indigo naturalis, 14-19 parts of Radix Isatidis, 17-20 parts of the root bark of Chinese wolf-berry, 8-11 parts of Radix Glycyrrhizae, 5-7 parts of honey.
Further, a kind of Chinese medicine composition for Intensive Care Therapy infection in respiratory system, by the raw material of following parts by weight Component is made:22 parts of asarum, 17 parts of Radix Ophiopogonis, 15 parts of reed root, 14 parts of gypsum, 20 parts of perilla leaf, 18 parts of Lasiosphaera fenzlii, 15 parts of indigo naturalis, plate 17 parts of blue root, 19 parts of the root bark of Chinese wolf-berry, 10 parts of Radix Glycyrrhizae, 6 parts of honey.
A kind of preparation method of the Chinese medicine composition for Intensive Care Therapy infection in respiratory system, prepares as follows:
(1) 15-28 parts of asarum, Radix Ophiopogonis 13-21 part, 8-19 parts of reed root, 7-15 parts of gypsum, purple are weighed respectively in parts by weight 15-23 parts of perilla leaf, 11-20 parts of Lasiosphaera fenzlii, 9-20 parts of indigo naturalis, 12-22 parts of Radix Isatidis, 11-21 parts of the root bark of Chinese wolf-berry, 7-11 parts of Radix Glycyrrhizae, bee It is 5-9 parts sweet;
(2) add water slightly boiled asarum, Radix Ophiopogonis, reed root, gypsum, perilla leaf, Lasiosphaera fenzlii, indigo naturalis, Radix Isatidis, the root bark of Chinese wolf-berry, Radix Glycyrrhizae It decocts three times, for the first time plus is equivalent to 10-13 times of above-mentioned raw materials gross mass and measures water, decoct 75-90min, second plus be equivalent to 8-10 times of above-mentioned raw materials gross mass measures water, decocts 45-60min, third time plus is equivalent to 6-8 times of above-mentioned raw materials gross mass and measures water, 25-45min is decocted, collecting decoction cools filtering, is concentrated under reduced pressure, and vacuum drying obtains dry extract, spare;
(3) the resulting Chinese medicine dry extract of step (2) is added into honey, auxiliary material, the finished dosage forms of clinical needs is made.
Tablet, pill, granule, oral can be made in a kind of Chinese medicine composition for Intensive Care Therapy infection in respiratory system Liquid, powder, tincture, capsule or syrup.
The effect of forming each bulk pharmaceutical chemicals of the invention activity is as follows:
The present invention is using asarum, Radix Ophiopogonis as monarch drug in a prescription.Asarum:Warm-natured acrid flavour;Return heart, lung, kidney channel;Expelling wind and clearing away cold, wind-expelling pain-stopping, It is sensible, warming lung and resolving fluid;For anemofrigid cold, have a headache, toothache, nasal congestion, allergic rhinitis, nasosinusitis, rheumatic arthralgia, sputum cough.Wheat Winter:This product is the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf);It is sweet in flavor, slight bitter, cold nature;Return heart, lung, stomach meridian;Yin-nourishing It promotes the production of body fluid, moistening lung and clearing away the heart-fire.
Reed root, gypsum, perilla leaf are ministerial drug of the invention.Reed root:It is cold in nature sweet in flavor;Distributed in lung channel, stomach meridian;Clearing heat and promoting fluid is removed It is tired, preventing or arresting vomiting, diuresis;For pyreticosis and polydipsia, gastropyretic vomiting, cough with lung heat, lung carbuncle pyemesis, puckery pain of heat gonorrhea.Gypsum:This product is sulfuric acid Saline minerals anhydrite race gypsum, the main (CaSO containing hydrous calcium sulfate4·2H2O), after excavation, silt and miscellaneous stone are removed;Sweet in flavor, It is pungent, property Great Cold;It attaches to the lung and stomach meridians;Clearing heat-fire, relieving restlessness are quenched the thirst.Perilla leaf:Warm-natured acrid flavour;Return lung, the spleen channel;Relieving exterior syndrome and dispelling cold, promoting the circulation of qi Stomach function regulating, for anemofrigid cold, cough vomiting.
Lasiosphaera fenzlii, indigo naturalis, Radix Isatidis, the root bark of Chinese wolf-berry are adjutant of the invention.Lasiosphaera fenzlii:Acrid flavour is mild-natured;It is clearing heat and detoxicating, promoting the dispersing function of the lung is sharp Pharynx, function arrogate to oneself surname dissipate.Indigo naturalis:Bitter is cold in nature;Clearing heat and detoxicating, cooling blood and hemostasis, is longer than heat-clearing.Lasiosphaera fenzlii and indigo naturalis Papillary, are played altogether The effect of clearing heat and detoxicating, reducing pharyngeal swelling analgesic, for treating abscess of throat because of person caused by heat evil fire toxin.Radix Isatidis:Cold in nature, taste is first It is bitter after slightly sweet;There is the effect of clearing heat and detoxicating, preventing cold, relieving sore-throat;It is dark reddish purple dark, rotten to be mainly used for treatment febrile virulent maculae, tongue The diseases such as larynx scarlet fever.Removing toxic substances relieving sore-throat.The root bark of Chinese wolf-berry:It is sweet natured;It is distributed in lung channel;Cool blood is used for chronic cough and dyspnea of deficiency type except precious, clearing lung-heat fall fire.
Radix Glycyrrhizae, honey make medicine for of the invention.Radix Glycyrrhizae:It is sweet in flavor, it is mild-natured;It invigorates the spleen and benefits qi, is clearing heat and detoxicating, expelling phlegm and arresting coughing, delaying Anxious analgesic, coordinating the drug actions of a prescription;For weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, wrist abdomen, four limbs contraction, swelling Swollen sore alleviates drug toxicity, is strong.Honey:《Compendium of Materia Medica》Carry " function being used as medicine has five, heat-clearing also, bowl spares also, removing toxic substances also, Moisturize also, analgesic.It is raw then cool in nature, therefore can heat-clearing;It is ripe then warm-natured, therefore can bowl spares;It is sweet and gentle, therefore can detoxify;Soft and Ru Ze, Therefore it can moisturize;It is slow to go urgency, therefore trusted subordinate's muscle sore pain can be stopped;With it can cause in, therefore hundred medicines can be reconciled, and with the same function of Radix Glycyrrhizae ".
The beneficial effects of the invention are as follows:The present invention utilizes drug matching principle, and a variety of medicinal materials are used cooperatively, are had developed A kind of Chinese medicine preparation that can treat Intensive Care Therapy infection in respiratory system, drug effective percentage are up to 98.7%, and quick, pharmacological property is delayed With toxic side effect is small, no dependence, is conducive to patient and mitigates symptom in time.The all medicine compatibility of the present invention is made a general survey of, is played altogether and inducing diaphoresis In, soothing the liver rising Yang, clearing heat-fire, nourishing Yin and promoting production of body fluid, eliminating dampness dissolving phlegm, sweating expelling pathogenic factors from muscles and skin, clearing heat and cooling blood, removing blood stasis and acesodyne, tonifying middle-Jiao and Qi, dispel Phlegm and relieving cough, diuresis of promoting the production of body fluid, the effect of reinforcing the spleen to benefit the lung are suitable for treatment Intensive Care Therapy infectious disease of respiratory system.
Specific embodiment
In order to enable those skilled in the art to more fully understand, technical solution of the present invention is practiced, below with reference to specific The invention will be further described for embodiment, but illustrated embodiment is not as a limitation of the invention.
Embodiment 1
A kind of Chinese medicine composition for Intensive Care Therapy infection in respiratory system of the present embodiment, by the raw material group of following parts by weight Divide and is made:22 parts of asarum, 17 parts of Radix Ophiopogonis, 15 parts of reed root, 14 parts of gypsum, 20 parts of perilla leaf, 18 parts of Lasiosphaera fenzlii, 15 parts of indigo naturalis, plate are blue 17 parts of root, 19 parts of the root bark of Chinese wolf-berry, 10 parts of Radix Glycyrrhizae, 6 parts of honey.
Preparation method:(1) it is grouped as by above-mentioned raw materials group and weighs asarum, Radix Ophiopogonis, reed root, gypsum, perilla leaf, horse respectively Suddenly, indigo naturalis, Radix Isatidis, the root bark of Chinese wolf-berry, Radix Glycyrrhizae, honey;
(2) add water slightly boiled asarum, Radix Ophiopogonis, reed root, gypsum, perilla leaf, Lasiosphaera fenzlii, indigo naturalis, Radix Isatidis, the root bark of Chinese wolf-berry, Radix Glycyrrhizae It decocts three times, for the first time plus is equivalent to 12 times of amount water of above-mentioned raw materials gross mass, decocts 80min, for the second time plus be equivalent to above-mentioned original Expect 9 times of amount water of gross mass, decoct 50min, third time, which adds, is equivalent to 7 times of amount water of above-mentioned raw materials gross mass, decocts 40min, merges Decocting liquid cools filtering, is concentrated under reduced pressure, and vacuum drying obtains dry extract, spare;
(3) the resulting Chinese medicine dry extract of step (2) is added into honey, auxiliary material, utilizes modern general Chinese materia medica preparation skill Oral solution is made in art.
Embodiment 2
A kind of Chinese medicine composition for Intensive Care Therapy infection in respiratory system of the present embodiment, by the raw material group of following parts by weight Divide and is made:20 parts of asarum, 15 parts of Radix Ophiopogonis, 12 parts of reed root, 12 parts of gypsum, 18 parts of perilla leaf, 15 parts of Lasiosphaera fenzlii, 13 parts of indigo naturalis, plate are blue 14 parts of root, 17 parts of the root bark of Chinese wolf-berry, 8 parts of Radix Glycyrrhizae, 5 parts of honey.
Preparation method:(1) it is grouped as by above-mentioned raw materials group and weighs asarum, Radix Ophiopogonis, reed root, gypsum, perilla leaf, horse respectively Suddenly, indigo naturalis, Radix Isatidis, the root bark of Chinese wolf-berry, Radix Glycyrrhizae, honey;
(2) add water slightly boiled asarum, Radix Ophiopogonis, reed root, gypsum, perilla leaf, Lasiosphaera fenzlii, indigo naturalis, Radix Isatidis, the root bark of Chinese wolf-berry, Radix Glycyrrhizae It decocts three times, for the first time plus is equivalent to 10 times of amount water of above-mentioned raw materials gross mass, decocts 75min, for the second time plus be equivalent to above-mentioned original Expect 8 times of amount water of gross mass, decoct 45min, third time, which adds, is equivalent to 6 times of amount water of above-mentioned raw materials gross mass, decocts 30min, merges Decocting liquid cools filtering, is concentrated under reduced pressure, and vacuum drying obtains dry extract, spare;
(3) the resulting Chinese medicine dry extract of step (2) is added into honey, auxiliary material, utilizes modern general Chinese materia medica preparation skill Syrup is made in art.
Embodiment 3
A kind of Chinese medicine composition for Intensive Care Therapy infection in respiratory system of the present embodiment, by the raw material group of following parts by weight Divide and is made:25 parts of asarum, 19 parts of Radix Ophiopogonis, 16 parts of reed root, 15 parts of gypsum, 21 parts of perilla leaf, 20 parts of Lasiosphaera fenzlii, 17 parts of indigo naturalis, plate are blue 19 parts of root, 20 parts of the root bark of Chinese wolf-berry, 11 parts of Radix Glycyrrhizae, 7 parts of honey.
Preparation method:(1) it is grouped as by above-mentioned raw materials group and weighs asarum, Radix Ophiopogonis, reed root, gypsum, perilla leaf, horse respectively Suddenly, indigo naturalis, Radix Isatidis, the root bark of Chinese wolf-berry, Radix Glycyrrhizae, honey;
(2) add water slightly boiled asarum, Radix Ophiopogonis, reed root, gypsum, perilla leaf, Lasiosphaera fenzlii, indigo naturalis, Radix Isatidis, the root bark of Chinese wolf-berry, Radix Glycyrrhizae It decocts three times, for the first time plus is equivalent to 13 times of amount water of above-mentioned raw materials gross mass, decocts 90min, for the second time plus be equivalent to above-mentioned original Expect 10 times of amount water of gross mass, decoct 60min, third time, which adds, is equivalent to 8 times of amount water of above-mentioned raw materials gross mass, decocts 45min, merges Decocting liquid cools filtering, is concentrated under reduced pressure, and vacuum drying obtains dry extract, spare;
(3) the resulting Chinese medicine dry extract of step (2) is added into honey, auxiliary material, utilizes modern general Chinese materia medica preparation skill Pill is made in art.
Embodiment 1-3 is the significant Chinese medicine composition of therapeutic effect, wherein 1 gained Intensive Care Therapy of embodiment breathing system The clinical application of togetherness dye disease treatment Chinese medicine:In 300 patients of 3 hospital's screening ages between 18-70 years old, wherein Women 150, male 150, wherein 100 patients are due to pulmonary infection;100 patients are due to tracheae or bronchus sense Dye;100 patients are throat, tonsillotome, nasal cavity infection.
The crowd is observed continuously in the last week of experiment, records symptom and variation, is randomly divided into two groups, experimental group And control group, experimental group use the made Chinese medicine of the embodiment of the present invention 1, control group uses commonly treatment respiratory system sense in the market The drug of dye.
Curative effect situation criterion:It is effective:Complications shape disappears substantially after medication seven days;Effectively:Disease hair after medication seven days Symptom is reduced;In vain:There is no any variation after taking seven days or once improves, the rear symptom restored to before treating again.
Instructions of taking:The oral solution that the embodiment of the present invention 1 is prepared is taken during treating, a 15mL is sooner or later each daily It takes once, continuously takes seven days, the results are shown in Table 1.
Table 1 takes the verifying of 1 products obtained therefrom therapeutic effect of embodiment
Experimental group Control group
Number of cases 150 150
Male's number of cases 75 75
Women number of cases 75 75
Pulmonary infection 50 50
Tracheae or bronchial infection 50 50
Throat, tonsillotome, nasal cavity infection 50 50
Effective number of cases 132 89
Effective number of cases 16 49
Invalid number of cases 2 12
It is efficient 98.7% 92%
Therapeutic effect:From table 1, it is apparent that taking treatment Intensive Care Therapy respiratory system obtained by the embodiment of the present invention 1 Effective and effective totally 148 (98.7%) of the experimental group of infection tcm product is invalid 2 (1%).And control group is effective Rate only reaches 92%, and the experimental group for taking treatment Intensive Care Therapy infection in respiratory system tcm product obtained by the present invention is substantially better than Take the control group of other drugs.
Disclosed above is only specific embodiments of the present invention, and still, the embodiment of the present invention is not limited to this, Ren Heben What the technical staff in field can think variation should all fall into protection scope of the present invention.

Claims (5)

1. a kind of Chinese medicine composition for Intensive Care Therapy infection in respiratory system, which is characterized in that by the raw material of following parts by weight Component is made:
15-28 parts of asarum, Radix Ophiopogonis 13-21 part, 8-19 parts of reed root, 7-15 parts of gypsum, 15-23 parts of perilla leaf, 11-20 parts of Lasiosphaera fenzlii, 9-20 parts of indigo naturalis, 12-22 parts of Radix Isatidis, 11-21 parts of the root bark of Chinese wolf-berry, 7-11 parts of Radix Glycyrrhizae, 5-9 parts of honey.
2. being used for the Chinese medicine composition of Intensive Care Therapy infection in respiratory system as described in claim 1, which is characterized in that by following The raw material components of parts by weight are made:
20-25 parts of asarum, Radix Ophiopogonis 15-19 part, 12-16 parts of reed root, 12-15 parts of gypsum, 18-21 parts of perilla leaf, Lasiosphaera fenzlii 15-20 Part, 13-17 parts of indigo naturalis, 14-19 parts of Radix Isatidis, 17-20 parts of the root bark of Chinese wolf-berry, 8-11 parts of Radix Glycyrrhizae, 5-7 parts of honey.
3. being used for the Chinese medicine composition of Intensive Care Therapy infection in respiratory system as claimed in claim 2, which is characterized in that by following The raw material components of parts by weight are made:
22 parts of asarum, 17 parts of Radix Ophiopogonis, 15 parts of reed root, 14 parts of gypsum, 20 parts of perilla leaf, 18 parts of Lasiosphaera fenzlii, 15 parts of indigo naturalis, Radix Isatidis 17 Part, 19 parts of the root bark of Chinese wolf-berry, 10 parts of Radix Glycyrrhizae, 6 parts of honey.
4. the preparation method of the Chinese medicine composition a method according to any one of claims 1-3 for Intensive Care Therapy infection in respiratory system, It is characterized in that, preparing as follows:
(1) 15-28 parts of asarum, Radix Ophiopogonis 13-21 part, 8-19 parts of reed root, 7-15 parts of gypsum, perilla leaf are weighed respectively in parts by weight 15-23 parts, 11-20 parts of Lasiosphaera fenzlii, 9-20 parts of indigo naturalis, 12-22 parts of Radix Isatidis, 11-21 parts of the root bark of Chinese wolf-berry, 7-11 parts of Radix Glycyrrhizae, honey 5-9 Part;
(2) asarum, Radix Ophiopogonis, reed root, gypsum, perilla leaf, Lasiosphaera fenzlii, indigo naturalis, Radix Isatidis, the root bark of Chinese wolf-berry, Radix Glycyrrhizae are added into the slightly boiled decoction of water Three times, it for the first time plus is equivalent to 10-13 times of above-mentioned raw materials gross mass and measures water, decoct 75-90min, second plus be equivalent to above-mentioned 8-10 times of total mass of raw material is measured water, decocts 45-60min, third time plus is equivalent to 6-8 times of above-mentioned raw materials gross mass and is measured water, is decocted 25-45min, collecting decoction cool filtering, are concentrated under reduced pressure, and vacuum drying obtains dry extract, spare;
(3) Chinese medicine dry extract obtained in step (2) is added into honey, auxiliary material, the finished dosage forms of clinical needs is made.
5. being used for the Chinese medicine composition of Intensive Care Therapy infection in respiratory system as claimed in claim 4, which is characterized in that in described Tablet, pill, granule, oral solution, powder, tincture, capsule or syrup can be made in drug composition.
CN201811020489.3A 2018-09-03 2018-09-03 A kind of Chinese medicine composition and preparation method for Intensive Care Therapy infection in respiratory system Pending CN108837090A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811020489.3A CN108837090A (en) 2018-09-03 2018-09-03 A kind of Chinese medicine composition and preparation method for Intensive Care Therapy infection in respiratory system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811020489.3A CN108837090A (en) 2018-09-03 2018-09-03 A kind of Chinese medicine composition and preparation method for Intensive Care Therapy infection in respiratory system

Publications (1)

Publication Number Publication Date
CN108837090A true CN108837090A (en) 2018-11-20

Family

ID=64189513

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811020489.3A Pending CN108837090A (en) 2018-09-03 2018-09-03 A kind of Chinese medicine composition and preparation method for Intensive Care Therapy infection in respiratory system

Country Status (1)

Country Link
CN (1) CN108837090A (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2431852A1 (en) * 2000-12-14 2002-06-20 Globoasia Llc. Herbal pharmaceutical compositions for treating immunological disorders
CN102475846A (en) * 2010-11-27 2012-05-30 冯文明 Pneumonia preventing and treating tablet
CN105572262A (en) * 2016-02-10 2016-05-11 李兴惠 Method for detecting traditional Chinese medicine composition heat clearing and dredging granules
CN106620234A (en) * 2017-03-11 2017-05-10 王艳萍 Cough-relieving traditional Chinese medicine composition and preparation method and application thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2431852A1 (en) * 2000-12-14 2002-06-20 Globoasia Llc. Herbal pharmaceutical compositions for treating immunological disorders
CN102475846A (en) * 2010-11-27 2012-05-30 冯文明 Pneumonia preventing and treating tablet
CN105572262A (en) * 2016-02-10 2016-05-11 李兴惠 Method for detecting traditional Chinese medicine composition heat clearing and dredging granules
CN106620234A (en) * 2017-03-11 2017-05-10 王艳萍 Cough-relieving traditional Chinese medicine composition and preparation method and application thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
王新陆: "《王新陆医论医案集》", 31 March 2016, 中国医药科技出版社 *
胡志坚: "《中药临证应用》", 31 August 1981, 内蒙古人民出版社 *
苗明三、孙玉信、王晓田: "《中药大辞典》", 30 June 2017, 山西科学技术出版社 *

Similar Documents

Publication Publication Date Title
CN104352587A (en) Ointment for treating rhinitis
CN104069474B (en) Traditional Chinese medicine composition for treating seborrheic alopecia and preparation method thereof
CN102755593A (en) Traditional Chinese medicine composition for treating qi goiter and preparation method thereof
CN106620097A (en) Cough-relieving plaster prepared from traditional Chinese medicine composition, and preparation method of cough-relieving plaster
CN101129755A (en) Orally taken traditional Chinese medicine composition for treating asthma
CN1931262B (en) Common cold treating Chinese medicine preparation
CN108837090A (en) A kind of Chinese medicine composition and preparation method for Intensive Care Therapy infection in respiratory system
CN105343274A (en) Drug combination having inflammation diminishing and cough relieving functions
CN110721303A (en) Traditional Chinese medicine composition for treating allergic rhinitis and application thereof
CN101317946B (en) Medicament for treating chronic bronchitis, pneumonectasis and preparation method thereof
CN110478416A (en) The composition and its preparation method and application for treating rheumatic rheumatoid arthritis
CN104173737A (en) Traditional Chinese medicine formula for treating pulmonary interstitial fibrosis
CN104147334A (en) Traditional Chinese medicine formula capable of eliminating phlegm
CN115531503B (en) External traditional Chinese medicine composition for novel coronavirus pneumonia recovery period, acupoint patch, preparation method and application
CN115300544B (en) Traditional Chinese medicine composition and patch for dispelling wind, relieving exterior syndrome, detumescence and inducing resuscitation and preparation method thereof
CN103920056B (en) Aerosol inhalation liquid for preventing postoperative tracheospasm and preparation method thereof
CN108126008A (en) Rosemary cordyceps sinensis ball
CN101327281A (en) Traditional Chinese medicine for treating facial paralysis caused by apoplexy
CN105381351A (en) Traditional Chinese medicine for treating infantile asthma caused by lung qi obstruction
CN105106814A (en) Traditional Chinese medicine combination for treating viral rhinitis
CN104826072A (en) Traditional Chinese medicine preparation for treating respiratory system infection and preparation method of traditional Chinese medicine preparation
CN108159219A (en) A kind of Chinese medicine for treating asthma in children
CN103948682A (en) Traditional Chinese medicine for treating arrhythmia caused by insufficiency of heart blood
CN108042676A (en) Chinese medicine preparation for allergic rhinitis and preparation method thereof
CN107496626A (en) It is a kind of to be used to treat pill medicine of nasal obstruction and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20181120

RJ01 Rejection of invention patent application after publication