CN106421103A - Chinese medicinal formula for curing chicken colibacillosis - Google Patents
Chinese medicinal formula for curing chicken colibacillosis Download PDFInfo
- Publication number
- CN106421103A CN106421103A CN201611161598.8A CN201611161598A CN106421103A CN 106421103 A CN106421103 A CN 106421103A CN 201611161598 A CN201611161598 A CN 201611161598A CN 106421103 A CN106421103 A CN 106421103A
- Authority
- CN
- China
- Prior art keywords
- radix
- chinese medicinal
- chicken colibacillosis
- chicken
- medicinal formulae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000287828 Gallus gallus Species 0.000 title claims abstract description 57
- 239000002994 raw material Substances 0.000 claims abstract description 15
- 239000003814 drug Substances 0.000 claims description 22
- 239000009806 pulsatillae Substances 0.000 claims description 13
- 241000746375 Andrographis Species 0.000 claims description 9
- 229940079593 drug Drugs 0.000 claims description 9
- 239000007788 liquid Substances 0.000 claims description 6
- 239000003651 drinking water Substances 0.000 claims description 5
- 235000020188 drinking water Nutrition 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims 1
- 240000002853 Nelumbo nucifera Species 0.000 claims 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims 1
- 238000004080 punching Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 14
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 239000003242 anti bacterial agent Substances 0.000 abstract description 2
- 229940088710 antibiotic agent Drugs 0.000 abstract description 2
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 2
- 241000218691 Cupressaceae Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 241000206469 Pulsatilla Species 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 235000013330 chicken meat Nutrition 0.000 description 42
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 14
- 201000010099 disease Diseases 0.000 description 12
- 241000588724 Escherichia coli Species 0.000 description 7
- 208000001848 dysentery Diseases 0.000 description 6
- 230000003115 biocidal effect Effects 0.000 description 5
- 230000012447 hatching Effects 0.000 description 4
- 208000015181 infectious disease Diseases 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- AYIRNRDRBQJXIF-NXEZZACHSA-N (-)-Florfenicol Chemical compound CS(=O)(=O)C1=CC=C([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)C=C1 AYIRNRDRBQJXIF-NXEZZACHSA-N 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 3
- 206010059866 Drug resistance Diseases 0.000 description 3
- 238000009360 aquaculture Methods 0.000 description 3
- 244000144974 aquaculture Species 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 229960003760 florfenicol Drugs 0.000 description 3
- 230000001900 immune effect Effects 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- 229960005486 vaccine Drugs 0.000 description 3
- GSDSWSVVBLHKDQ-UHFFFAOYSA-N 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Chemical compound FC1=CC(C(C(C(O)=O)=C2)=O)=C3N2C(C)COC3=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-UHFFFAOYSA-N 0.000 description 2
- RFLHUYUQCKHUKS-JUODUXDSSA-M Ceftiofur sodium Chemical compound [Na+].S([C@@H]1[C@@H](C(N1C=1C([O-])=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1CSC(=O)C1=CC=CO1 RFLHUYUQCKHUKS-JUODUXDSSA-M 0.000 description 2
- 108010078777 Colistin Proteins 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 244000052616 bacterial pathogen Species 0.000 description 2
- 229960004467 ceftiofur sodium Drugs 0.000 description 2
- 229960003346 colistin Drugs 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 229940031551 inactivated vaccine Drugs 0.000 description 2
- 230000002147 killing effect Effects 0.000 description 2
- 210000001161 mammalian embryo Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- JORAUNFTUVJTNG-BSTBCYLQSA-N n-[(2s)-4-amino-1-[[(2s,3r)-1-[[(2s)-4-amino-1-oxo-1-[[(3s,6s,9s,12s,15r,18s,21s)-6,9,18-tris(2-aminoethyl)-3-[(1r)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-h Chemical compound CC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@H]([C@@H](C)O)CN[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O.CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@H]([C@@H](C)O)CN[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O JORAUNFTUVJTNG-BSTBCYLQSA-N 0.000 description 2
- 229960001699 ofloxacin Drugs 0.000 description 2
- XDJYMJULXQKGMM-UHFFFAOYSA-N polymyxin E1 Natural products CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O XDJYMJULXQKGMM-UHFFFAOYSA-N 0.000 description 2
- KNIWPHSUTGNZST-UHFFFAOYSA-N polymyxin E2 Natural products CC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O KNIWPHSUTGNZST-UHFFFAOYSA-N 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 208000037920 primary disease Diseases 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- FFRBMBIXVSCUFS-UHFFFAOYSA-N 2,4-dinitro-1-naphthol Chemical compound C1=CC=C2C(O)=C([N+]([O-])=O)C=C([N+]([O-])=O)C2=C1 FFRBMBIXVSCUFS-UHFFFAOYSA-N 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010052804 Drug tolerance Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 206010018691 Granuloma Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010022653 Intestinal haemorrhages Diseases 0.000 description 1
- QYZBCWXZSYTIOY-UHFFFAOYSA-N Mercuric oxide Chemical compound [O-2].[Hg+2] QYZBCWXZSYTIOY-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000269799 Perca fluviatilis Species 0.000 description 1
- 241000269800 Percidae Species 0.000 description 1
- 206010034464 Periarthritis Diseases 0.000 description 1
- 206010071301 Perihepatitis Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 208000018569 Respiratory Tract disease Diseases 0.000 description 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 235000009392 Vitis Nutrition 0.000 description 1
- 241000219095 Vitis Species 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000001004 anti-acetylcholinic effect Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 210000001669 bursa of fabricius Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000009351 contact transmission Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 210000002969 egg yolk Anatomy 0.000 description 1
- 206010014599 encephalitis Diseases 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 206010030306 omphalitis Diseases 0.000 description 1
- 208000010403 panophthalmitis Diseases 0.000 description 1
- 230000007918 pathogenicity Effects 0.000 description 1
- 208000008494 pericarditis Diseases 0.000 description 1
- 206010034674 peritonitis Diseases 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 235000013594 poultry meat Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 208000029667 primary bacterial infectious disease Diseases 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 150000007660 quinolones Chemical class 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 208000037921 secondary disease Diseases 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 230000005570 vertical transmission Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a Chinese medicinal formula for curing chicken colibacillosis. The Chinese medicinal formula comprises the following raw materials in percentage by weight: 14-16% of golden cypress, 14-16% of radix scutellariae, 14-16% of Chinese pulsatilla root, 14-16% of radix puerariae, 9.5-10.5% of rhizoma atractylodis, 9.5-10.5% of pericarpium citri reticulatae, 7-8% of herba andrographitis, 7-8% of radix rehmanniae recen, and 4.5-5.5% of liquorice. The pure traditional Chinese medicines are used to cure and prevent chicken colibacillosis, the abuse of antibiotics and the like is effectively avoided, no toxic or side effect is produced, the effect is good, and the cost is low.
Description
Technical field
The present invention relates to technical field of Chinese medicines, treats chicken colibacillosis Chinese medicinal formulae in particular to one kind.
Background technology
Chicken colibacillosis are the abbreviations of Escherichia coli, and the antibacterial is widely present in nature, and animal and bird intestines
Normal perch bacterium, many bacterial strain no pathogenicities, generally from the escherichia coli described in veterinary's angle, refer to pathogenic bacterium
Strain.Nowadays with the intensive manufacture of aquaculture, chicken colibacillosis increasingly become harm poultry husbandry great bacterial diseases it
One.Since the 80's of 20th century, with emergence and the development of China's aquaculture, the disease spreads in China various places and spreads, entirely
All there is the report that the disease occurs state various places, and the disease is often with the disease such as chronic respiratory tract disease, newcastle, infectious bursa of Fabricius simultaneously
Morbidity or secondary disease.As colibacillosiss are also easy to produce drug resistance, very big difficulty is brought to the disease is prevented and treated.Nearly ten years, old institute
Black chicken breed purity and intensive culture level are improved constantly, in order to ensure the black chicken of old institute（Egg）Fragrant in taste is fine and smooth, natural richness
Selenium, nutritious qualitative characteristics, for a long time, raiser is fed black chicken and is herded with daytime and raises scattered, and night enters house perches and wait slightly
The way to manage that puts, but this mode of raising scattered causes the black chicken of old institute easily ehec infection disease, and colibacillosiss are to trouble
One of difficult problem of " raising pattern scattered " maximum, in the black chicken cultivation of old institute, morbidity amount is in rising trend in recent years, it has also become harm is old
The primary bacterial infectious disease of the black chicken aquaculture of institute.
Primary disease can all occur throughout the year, and coop ventilation at the beginning of You Yidong last month of spring is more multiple when bad.The chicken at various ages
Primary disease can be infected, but young chicken most easily occurs.The route of infection have three kinds：One kind is that Disease in Infants hatching egg carries disease germs vertical transmission；Two are
Hatching process hatching egg pollution spread is to embryo；Three is that source of disease is invaded by the door such as digestive tract, Xi Hu road, anus, skin trauma
Contact transmission.Disease caused by it belongs to opportunistic illnesses category, in the chicken house that feeding and management is not good at, sanitary condition is poor, when
When the resistance of chicken reduces, will ehec infection disease.In the good chicken farm of feeding and management and sanitary condition, chicken immunity and
Resistance is stronger, and Colibacillosis rate is relatively low, and caused loss is less.
Colibacillary antigen construct complexity, pathogenic serotype is a lot of, it was reported that the existing pathogenic serotype of China
Existing kind more than 70, principal causative type is O etc..Due to serotype difference, clinical manifestation and epidemiological features are also different, main table
It is now acute sepsis（Perihepatitis, pericarditiss, peritonitis）, chickling omphalitis yolk capsulitis, airsacculitis, enteritis, encephalitis, defeated scorching pipe
Inflammation, granuloma, joint of the lower extremity swollen, panophthalmitis of scorching and foot pad etc., can also cause hatching dead germ and weak embryo.
Escherichia coli inactivated vaccine generally includes O1、O2、O78、O35These four common serotype, cause in a chicken farm
The bacterial strain of disease often has several serotypes, if them and above-mentioned 4 serotype degree of agreements height, immune effect is preferable, instead
The low then immune effect of degree of agreement undesirable, same vaccine is used for different regions, different chicken houses, and effect is variant.At present,
The vaccine of domestic production now is limited due to its protective rate, and bacterial strain degree of agreement is not high, and duration of immunity is short, troublesome poeration, is promoting
In encounter larger resistance, just make the vaccine production of colibacillosiss encounter a larger difficult problem.From the point of view of putting into practice in recent years, the city
Once escherichia coli inactivated vaccine is crossed in immunity for several main Jiu Yuanhei chicken plants, but immune effect effect is poor, and city's model is described
The coli strain for enclosing interior chicken farm is low with above-mentioned four kinds of serotype degree of agreements, so many Jiu Yuanhei chicken plants are so far
Yet colibacillary epidemic prevention is not listed in immune programme for children.
In the medicine for preventing and treating the black chicken colibacillosis of old institute, it is currently mainly used chemicalses and antibiotic is prevented
Control, common antibiotics mainly have：Florfenicol, quinolones, cephalo-type etc., but these medicines are mostly strong, malicious with drug resistance
Property larger, the relatively costly, feature of residual weight, in breeding process not science, blindly the phenomenon of abuse antimicrobial drug more serious, some
Chemicalses and antibiotic have certain toxicity, side effect, can pass to the mankind by meat, egg, bring very to food hygiene
Big problem.Due to a large amount of uses of chemicalses and antibiotic, make colibacillary drug tolerance of strain more and more stronger, Antibiotic Resistance
Also increasingly wider, some coli strains even to not yet for veterinary clinic new antibiotic also show very strong resistance to
The property of medicine.And the increase with drug resistance, some chemical drugss are difficult to control to the state of an illness, not only cause drug waste, but also prolong
The state of an illness, causes very big economic loss to raiser by mistake, and people have to seek damage of the new means of prevention to control the disease
Evil.
Content of the invention
For the problems referred to above, the present invention proposes one kind and treats chicken colibacillosis Chinese medicinal formulae, using Chinese medicine preparation, has
Effect treatment chicken colibacillosis, and have no toxic side effect.
To achieve these goals, the technical solution adopted in the present invention is, one kind treats chicken colibacillosis prescription
Agent, its raw materials by weight is calculated as：Cortex Phellodendri 14～16%, Radix Scutellariae 14～16%, the Radix Pulsatillae 14～16%, Radix Puerariae 14～16%,
Rhizoma Atractylodis 9.5～10.5%, Pericarpium Citri Reticulatae 9.5～10.5%, Herba Andrographis 7～8%, Radix Rehmanniae 7～8%, Radix Glycyrrhizae 4.5～5.5%.
Preferably, one kind treats chicken colibacillosis Chinese medicinal formulae, its raw materials by weight is calculated as：Cortex Phellodendri 15%,
Radix Scutellariae 15%, the Radix Pulsatillae 15%, Radix Puerariae 15%, Rhizoma Atractylodis 10%, Pericarpium Citri Reticulatae 10%, Herba Andrographis 7.5%, Radix Rehmanniae 7.5%, Radix Glycyrrhizae 5%.
Preferably, in raw material, by weight, Cortex Phellodendri:Radix Scutellariae=1:1.
Preferably, in raw material, by weight, the Radix Pulsatillae:Radix Puerariae=1:1.
Further, described one kind treats chicken colibacillosis Chinese medicinal formulae, is 0.5～5g per only chicken consumption.
Preferably, described one kind treats chicken colibacillosis Chinese medicinal formulae, it is 1～2.5g/ days per only chicken consumption.
Further, described one kind treats chicken colibacillosis Chinese medicinal formulae, is used in mixed way in feedstuff by adding.
Further, by proportion compatibility, 100 mesh sieves are crossed after crushing, adds water to cook twice, collecting decoction, after concentrated medicament,
Add in the drinking water of chicken.
Preferably, this prescription proportion compatibility is pressed, 100 mesh sieves are crossed after crushing, add water to cook twice, collecting decoction, dense
Shorten medicinal liquid of every 1mL containing 1g crude drug into, after medicinal liquid dilution, supply whole day drinking-water.
The present invention treats chicken colibacillosis using Chinese herbal medicine compatibility, has no toxic side effect, good drug efficacy, effectively can prevent and
Treatment chicken colibacillosis, while the resistivity of chicken is lifted, and reagent cost is cheap.
In raw material, it is Rhizoma Atractylodis, Radix Puerariae, Pericarpium Citri Reticulatae that monarch drug is Cortex Phellodendri, Radix Scutellariae, the Radix Pulsatillae, ministerial drug, and Herba Andrographis, Radix Rehmanniae are assistant
Medicine, makes medicine for Radix Glycyrrhizae.
Cortex Phellodendri：With broad-spectrum antibacterial action, to escherichia coli, S. aureus L-forms, etc. all have stronger inhibitory or killing effect, for heat clearing away
Dampness, eliminating fire and detoxication, also certain stomach invigorating, function of gallbladder promoting, diuresis, being apt to damp-heat in lower-JIAO is driven, is dysentery to be controlled in key medicine.Though Cortex Phellodendri
So effect is slightly below Rhizoma Coptidis, but its price 12-18 unit/kilogram.
Radix Scutellariae：Containing Radix Scutellariae element, Radix Scutellariae glycoside, have functions that heat clearing away, dampness, only removing toxic substances, intestinal bleeding, to streptococcus, gold
Portugal bacterium, escherichia coli, bacillus pyocyaneus etc. all have inhibitory or killing effect, the work(with Cortex Phellodendri prescription with collaboration, potentiation.
The Radix Pulsatillae：With heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, to dysentery bacterium, Bacillus typhi, bacillus pyocyaneus, golden yellow Fructus Vitis viniferae
Coccus, escherichia coli and influenza virus etc. all have inhibitory action, for hygropyretic dysentery or fulminant dysentery, also have convergence to gastrointestinal mucosa
And anastalsis, especially good to dysentery effect, and price 18-25 unit/kilogram.
Radix Puerariae：Have functions that expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst, Shengyang Zhixie, control the exterior syndrome of affection due to external wind and heat, can with Rhizoma Coptidis,
Radix Scutellariae, Radix Glycyrrhizae equivalent are used.
Rhizoma Atractylodis：With rheumatism, drying damp and strengthening spleen effect, also significantly row's potassium, sodium effect, acts on shield kidney, and
The heat clearing and damp drying effect of Cortex Phellodendri can be strengthened, as the accessory drugss of Cortex Phellodendri.
Pericarpium Citri Reticulatae：Spleen invigorating qi-regulating, the work(of bath humidifying expectorant, Li Shizhen (1518-1593 A.D.) is thought：" Pericarpium Citri tangerinae hardship can rush down can dry pungent energy dissipate, wet energy and, its
All kinds of diseases and ailments are controlled, the work(of qi-regulating dampness are always taken, is then mended with tonic, then rush down with cathartic, then rise with Hydrargyri Oxydum Rubrum, then drop with drop medicine ", it is seen that old
Skin is used to be made with assistant and different, and Pericarpium Citri Reticulatae low price.
Radix Glycyrrhizae：With invigorating middle warmer and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the property of medicine is relaxed, is had to anti-acetylcholine
Effect.This prescription is used as coordinating the actions of various ingredients in a prescription.
Specific embodiment
Below by specific embodiment, the present invention is described in further detail.
Embodiment 1：One kind treats chicken colibacillosis Chinese medicinal formulae, and its raw materials by weight is calculated as：Cortex Phellodendri 15%,
Radix Scutellariae 15%, the Radix Pulsatillae 15%, Radix Puerariae 15%, Rhizoma Atractylodis 10%, Pericarpium Citri Reticulatae 10%, Herba Andrographis 7.5%, Radix Rehmanniae 7.5%, Radix Glycyrrhizae 5%.The Chinese medicine
Used in prescription adds feedstuff, 0.5～5g/ of average whole day dosage is only.
1-8 cage being chosen, 50 50 age in days chickens being grown per cage, 1-4 cage uses Chinese medicinal formulae of the present invention, averagely
Whole day dosage（G/ is only）Respectively 0.5,1,1.5,2,5-8 cage is respectively using ofloxacin, florfenicol, ceftiofur
Sodium, colistin, average whole day dosage is only 0.3g/, after continuously raising 20, obtains following table.（Wherein Chinese medicine formula
44 yuan/kilogram, 300 yuan/kilogram of ofloxacin, 500 yuan/kilogram of florfenicol, 800 yuan/kilogram of ceftiofur sodium, colistin
400 yuan/kilogram；）
Embodiment 2：One kind treats chicken colibacillosis Chinese medicinal formulae, and its raw materials by weight is calculated as：Cortex Phellodendri 14%, Radix Scutellariae
14%th, the Radix Pulsatillae 16%, Radix Puerariae 16%, Rhizoma Atractylodis 10.5%, Pericarpium Citri Reticulatae 9.5%, Herba Andrographis 8%, Radix Rehmanniae 7.5%, Radix Glycyrrhizae 4.5%.The Chinese medicine
Used in prescription adds feedstuff, 1～2.5g/ of average whole day dosage is only.
Embodiment 3：One kind treats chicken colibacillosis Chinese medicinal formulae, and its raw materials by weight is calculated as：Cortex Phellodendri 14%,
Radix Scutellariae 16%, the Radix Pulsatillae 16%, Radix Puerariae 14%, 10 % of Rhizoma Atractylodis, Pericarpium Citri Reticulatae 10%, Herba Andrographis 7.5%, Radix Rehmanniae 7.5%, Radix Glycyrrhizae 5%.In this
Used in prescription agent adds feedstuff, 2.5～5g/ of average whole day dosage is only.
Embodiment 4：, one kind treats chicken colibacillosis Chinese medicinal formulae, and its raw materials by weight is calculated as：Cortex Phellodendri 16%,
Radix Scutellariae 16%, the Radix Pulsatillae 14%, Radix Puerariae 14%, Rhizoma Atractylodis 9.5%, Pericarpium Citri Reticulatae 10.5%, Herba Andrographis 7%, Radix Rehmanniae 8%, Radix Glycyrrhizae 5%.By compatibility
Ratio, crosses 100 mesh sieves after crushing, adds water to cook twice, collecting decoction, after concentrated medicament, adds in the drinking water of chicken.
Embodiment 5：One kind treats chicken colibacillosis Chinese medicinal formulae, and its raw materials by weight is calculated as：Cortex Phellodendri 15%,
Radix Scutellariae 15%, the Radix Pulsatillae 15%, Radix Puerariae 15%, Rhizoma Atractylodis 10%, Pericarpium Citri Reticulatae 10%, Herba Andrographis 7.5%, Radix Rehmanniae 7%, Radix Glycyrrhizae 5.5%.By we
Agent proportion compatibility is combined into 10 kilograms.100 mesh sieves are crossed after crushing, add water to cook twice, collecting decoction, be condensed into every 1mL
Medicinal liquid containing 1g crude drug, supplies whole day drinking-water after medicinal liquid dilution.
The preferred embodiments of the present invention are the foregoing is only, the present invention is not limited to, for the skill of this area
For art personnel, can there are various modifications and variations in the spirit and principles in the present invention, the modification of these equivalents or replacement etc.,
It is all contained within protection scope of the present invention.
Claims (9)
1. one kind treats chicken colibacillosis Chinese medicinal formulae, it is characterised in that its raw materials by weight is calculated as：Cortex Phellodendri 14～
16%th, Radix Scutellariae 14～16%, the Radix Pulsatillae 14～16%, Radix Puerariae 14～16%, Rhizoma Atractylodis 9.5～10.5%, Pericarpium Citri Reticulatae 9.5～10.5%, punching
Lotus 7～8%, Radix Rehmanniae 7～8%, Radix Glycyrrhizae 4.5～5.5%.
2. one kind according to claim 1 treats chicken colibacillosis Chinese medicinal formulae, it is characterised in that its raw material is by weight
Percentages are：Cortex Phellodendri 15%, Radix Scutellariae 15%, the Radix Pulsatillae 15%, Radix Puerariae 15%, Rhizoma Atractylodis 10%, Pericarpium Citri Reticulatae 10%, the Herba Andrographis 7.5%, Radix Rehmanniae
Yellow 7.5%, Radix Glycyrrhizae 5%.
3. one kind according to claim 1 and 2 treats chicken colibacillosis Chinese medicinal formulae, it is characterised in that：In raw material, press
Weight portion meter, Cortex Phellodendri:Radix Scutellariae=1:1.
4. one kind according to claim 1 and 2 treats chicken colibacillosis Chinese medicinal formulae, it is characterised in that：In raw material, press
Weight portion meter, the Radix Pulsatillae:Radix Puerariae=1:1.
5. one kind according to claim 1 treats chicken colibacillosis Chinese medicinal formulae, it is characterised in that：Per only chicken consumption it is
0.5～5g/ days.
6. one kind according to claim 5 treats chicken colibacillosis Chinese medicinal formulae, it is characterised in that：Per only chicken consumption it is
1～2.5g/ days.
7. one kind according to claim 1 treats chicken colibacillosis Chinese medicinal formulae, it is characterised in that：By adding feedstuff
In be used in mixed way.
8. one kind according to claim 1 treats chicken colibacillosis Chinese medicinal formulae, it is characterised in that：By proportion compatibility,
100 mesh sieves are crossed after crushing, add water to cook twice, collecting decoction, after concentrated medicament, add in the drinking water of chicken.
9. one kind according to claim 8 treats chicken colibacillosis Chinese medicinal formulae, it is characterised in that：Described medicinal liquid is dense
Medicinal liquid after contracting, per 1mL containing 1g crude drug.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611161598.8A CN106421103A (en) | 2016-12-15 | 2016-12-15 | Chinese medicinal formula for curing chicken colibacillosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611161598.8A CN106421103A (en) | 2016-12-15 | 2016-12-15 | Chinese medicinal formula for curing chicken colibacillosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106421103A true CN106421103A (en) | 2017-02-22 |
Family
ID=58217704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611161598.8A Pending CN106421103A (en) | 2016-12-15 | 2016-12-15 | Chinese medicinal formula for curing chicken colibacillosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106421103A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111658706A (en) * | 2020-06-24 | 2020-09-15 | 天津九州大地饲料有限公司 | Traditional Chinese medicine additive for feed, preparation method and feed |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN101209305A (en) * | 2006-12-25 | 2008-07-02 | 天津市润拓生物技术有限公司 | Chinese medicinal oral liquid for treating colibacillosis of avian |
| CN104688883A (en) * | 2015-03-27 | 2015-06-10 | 天津市畜牧兽医研究所 | Traditional Chinese medicine composition containing humifuse euphorbia herbs, radix sophorae flavescentis and scutellaria baicalensis and preparation method thereof |
-
2016
- 2016-12-15 CN CN201611161598.8A patent/CN106421103A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN101209305A (en) * | 2006-12-25 | 2008-07-02 | 天津市润拓生物技术有限公司 | Chinese medicinal oral liquid for treating colibacillosis of avian |
| CN104688883A (en) * | 2015-03-27 | 2015-06-10 | 天津市畜牧兽医研究所 | Traditional Chinese medicine composition containing humifuse euphorbia herbs, radix sophorae flavescentis and scutellaria baicalensis and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111658706A (en) * | 2020-06-24 | 2020-09-15 | 天津九州大地饲料有限公司 | Traditional Chinese medicine additive for feed, preparation method and feed |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101543263B (en) | Chinese medicinal herb additive for meat ducks and application | |
| CN102845638A (en) | Duck feed capable of preventing and treating avian influenza and Chinese herbal additive used therein | |
| CN106039248A (en) | Formula for traditional Chinese medicines for treating different types of porcine diarrhea | |
| CN103006758A (en) | Chinese medicament composition for treating infectious bursal disease and preparation method thereof | |
| CN101658579A (en) | Chinese medicinal composition for treating pig colibacillosis and preparation method thereof | |
| CN104739963A (en) | Preparation method of Chinese medicinal micro-ecological oral preparation for preventing chicken colibaciuosis | |
| CN104547997B (en) | A kind of Chinese medicine composition for treating piglet epidemic diarrhea | |
| CN103006820A (en) | Chinese medicinal composition with functions of clearing heat and drying dampness and preparation method thereof | |
| CN103041005A (en) | Traditional Chinese medicine composition with effect of astringing intestine to stop diarrhea, and preparation method thereof | |
| CN102552653A (en) | Traditional Chinese medicinal composition with phlegm reducing and cough relieving functions and preparation method thereof | |
| CN103272091A (en) | Traditional Chinese medicinal oral preparation for treating chicken coccidiosis and preparation method thereof | |
| CN105688157A (en) | Traditional Chinese medicine compound preparation for resisting swine influenza virus and preparing method thereof | |
| CN106421103A (en) | Chinese medicinal formula for curing chicken colibacillosis | |
| CN103636968A (en) | Anti-avian influenza feed additive | |
| CN102028798A (en) | Traditional Chinese medicine composite for treating respiratory disease of livestock and poultry | |
| CN101422539A (en) | Traditional Chinese medicine oral liquid for treating livestock and poultry virus bacteria mixed infection | |
| CN101209293A (en) | Chinese medicinal granule with heat-clearing, detoxication, wind-expelling and cold-expelling efficacy | |
| CN102988548A (en) | Chinese medicinal composition with function of astringing intestine to stop diarrhea, preparation method thereof | |
| CN103083453A (en) | Traditional Chinese medicine for treating respiratory disease | |
| CN101376006A (en) | Chinese medicine oral liquid with heat-clearing and detoxicating, cough-suppressing and asthma-relieving functions as well as application thereof for livestock and poultry | |
| CN110652543A (en) | Preparation method and application of Chinese herbal medicine preparation for treating live pig viral enteritis | |
| CN104644742A (en) | Traditional Chinese medicine composition for treating infectious rhinitis of chicken and preparation method thereof | |
| CN108079104A (en) | A kind of traditional Chinese medicine oral liquid for treating avian staphylocosis and preparation method thereof | |
| CN103263483B (en) | Medicament used for treating livestock virus and bacteria infections and prepared from traditional Chinese medicines and preparation method of medicament | |
| CN101744866B (en) | Traditional Chinese medicine composition for preventing and treating culture diseases of livestock and poultry, preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170222 |