CN106420756A - 抑制jak途径的组合物和方法 - Google Patents
抑制jak途径的组合物和方法 Download PDFInfo
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- CN106420756A CN106420756A CN201610848344.7A CN201610848344A CN106420756A CN 106420756 A CN106420756 A CN 106420756A CN 201610848344 A CN201610848344 A CN 201610848344A CN 106420756 A CN106420756 A CN 106420756A
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K9/0012—Galenical forms characterised by the site of application
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P27/04—Artificial tears; Irrigation solutions
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Urology & Nephrology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US22919109P | 2009-07-28 | 2009-07-28 | |
| US61/229,191 | 2009-07-28 | ||
| CN2010800344786A CN102470135A (zh) | 2009-07-28 | 2010-07-28 | 抑制jak途径的组合物和方法 |
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| CN106420756A true CN106420756A (zh) | 2017-02-22 |
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| US (1) | US20110028503A1 (https=) |
| EP (1) | EP2459195A1 (https=) |
| JP (1) | JP5738292B2 (https=) |
| KR (1) | KR101740076B1 (https=) |
| CN (2) | CN106420756A (https=) |
| AU (3) | AU2010281404A1 (https=) |
| BR (1) | BR112012002001A2 (https=) |
| CA (1) | CA2768543C (https=) |
| MX (1) | MX337849B (https=) |
| RU (1) | RU2557982C2 (https=) |
| WO (1) | WO2011017178A1 (https=) |
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| CA2857189A1 (en) * | 2011-12-08 | 2013-06-13 | Rigel Pharmaceuticals, Inc. | Topical formulation for administering a compound |
| CN104902892A (zh) * | 2012-02-02 | 2015-09-09 | 悉尼大学 | 泪液膜稳定性的改进 |
| JP2015528501A (ja) * | 2012-09-12 | 2015-09-28 | ライジェル ファーマシューティカルズ， インコーポレイテッド | 白斑の治療法 |
| CA2898644A1 (en) * | 2013-01-24 | 2014-07-31 | Rigel Pharmaceuticals, Inc. | Composition for ophthalmic administration |
| CN105073112B (zh) * | 2013-03-13 | 2017-12-29 | 参天制药株式会社 | 睑板腺功能障碍的治疗剂 |
| WO2015019365A1 (en) | 2013-08-07 | 2015-02-12 | Cadila Healthcare Limited | N-cyanomethylamides as inhibitors of janus kinase |
| JP6427497B2 (ja) * | 2013-10-21 | 2018-11-21 | 日本たばこ産業株式会社 | 眼疾患の治療剤又は予防剤 |
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- 2010-07-28 RU RU2012103538/15A patent/RU2557982C2/ru active
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| CA2768543C (en) | 2017-06-20 |
| AU2018217196A1 (en) | 2018-08-30 |
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| MX337849B (es) | 2016-03-09 |
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| AU2016225851A1 (en) | 2016-09-29 |
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| JP5738292B2 (ja) | 2015-06-24 |
| US20110028503A1 (en) | 2011-02-03 |
| WO2011017178A1 (en) | 2011-02-10 |
| BR112012002001A2 (pt) | 2016-05-10 |
| MX2012001134A (es) | 2012-02-28 |
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